Publications

restriction of gut-derived endotoxin impairs dna synthesis for liver regeneration.	the influence of restricting gut-derived endotoxin availability on liver regeneration after partial hepatectomy was evaluated. partial hepatectomy was performed by 67% liver resection of ether-anesthetized rats. liver regeneration was quantified after partial hepatectomy by [3h]thymidine incorporation into hepatic dna; endotoxemia due to absorption of endogenous endotoxin from the gut into the portal circulation was determined by qualitative lysate assay of perchloric acid-extracted plasma sampl ...	1985	3904484
salmonella bacteremia associated with the acquired immunodeficiency syndrome (aids).	six cases of bacteremia due to serotypes of salmonella enteritidis are described in patients with the acquired immunodeficiency syndrome (aids). in four instances the bacteremia was recurrent despite appropriate antimicrobial treatment. neither a gastrointestinal tract source nor any other focus of infection could be identified in four of the six patients. in one patient an unusual salmonella infection, ie, pyelonephritis, was noted. the discovery of salmonella sepsis led in four cases to the in ...	1985	3904653
increase in the susceptibility of salmonella strains to bactericidal activity of cord serum following treatment with agents disturbing surface structures.	salmonella strains resistant to normal cord serum were found to become susceptible to it when the outer membrane was damaged by colistin, adult normal serum or tris-hcl buffer. the present results indicate that after such treatment cord sera exert bactericidal effect, despite significant deficiencies in factors playing an essential role in this process.	1985	3904666
endogenous gut-derived bacterial endotoxin tonically primes pancreatic secretion of insulin in normal rats.	this laboratory has proposed that endogenous gut-derived bacterial endotoxin primes the pancreatic secretion of insulin in normal rats. endogenous lipopolysaccharide (lps) is continually absorbed from the gut into intestinal capillaries, and low-grade portal venous endotoxemia is the status quo. under physiologic conditions, kupffer cells of the liver totally phagocytize and degrade endotoxin from the portal circulation. evidence from this and other laboratories indicates that administration of ...	1985	3905458
leads from the mmwr. turkey-associated salmonellosis at an elementary school--georgia.		1985	3906156
gallium-67 localization in a mycotic aneurysm of the thoracic aorta.	localization of ga-67 in a mycotic aneurysm of the thoracic aorta in a renal transplant recipient is reported. this procedure complements other imaging methods in the diagnosis of this serious condition and may be preferable to in-111 leukocytes because of its ready availability.	1985	3907924
in vitro blastogenic response and immunoglobulin synthesis in murine spleen cells stimulated with lipopolysaccharides from campylobacter jejuni and campylobacter coli.	lipopolysaccharides isolated from strains of campylobacter jejuni and campylobacter coli were mitogenic for spleen cells as measured by 3h-thymidine incorporation. the incorporation was dose dependent with an increase with increased concentration of lps. addition of lps beyond 500 micrograms/ml gave inhibition of incorporation. stimulation of the spleen cells for 3 days with lps led to a polyclonal activation of immunoglobulin synthesis. the amount of immunoglobulins synthesised showed a maximum ...	1985	3909739
in vitro lymphokine release by lymphocytes from mice infected with salmonella.	lymphocytes generated in mice by infection with salmonella enteritidis 11rx release interleukin 2 and macrophage activation factor upon subsequent in vitro culture with bacterial antigens. lymphokine release requires the co-culture of non-adherent sensitized lyt 1+2- t cells and adherent metabolically active accessory cells; the interaction between these two populations is restricted by the h-2 i-a locus. following systemic immunization with the 11rx strain, the two lymphokines are produced in p ...	1985	3911930
[rhabdomyolysis and salmonella enteritidis infection].		1985	3912628
spectrofluorometric and microfluorometric quantitation of antibacterial antibodies, using indirect immune fluorescence. preliminary report.	the igg-fraction of rabbit hyperimune serum raised towards smooth salmonella typhimurium 395 ms (parent strain) and rough 395 mr10 (rd-mutant) was used in indirect immunofluorescence with bacteria in suspension or adsorbed to glass microscope slides. in the first case, igg-mediated fluorescence was determined with a standard cuvette-type spectrofluorometer; in the second case, in epifluorescence mode with a microscope fluorometer. in both assays the igg solution could be diluted to about 0.1 mic ...	1985	3914822
phage types and epidemiological significance of salmonella enteritidis strains in hungary between 1976 and 1983.	in hungary, 14 819 human salmonella enteritidis strains were isolated between 1976 and 1983. phage type was determined of 10 132 human strains originating from 6852 foci, and of 711 strains isolated from animals and water in this period. the human strains were typable in 99.4% and they belonged into 21 phage types. five phage types (1, 4, 7, 16 and 17) were more frequent than 1%. phage type 7 predominated among the strains isolated between 1976 and 1980, including 65.6%-89.3% of the strains. the ...	1985	3915176
reactive hyperemic responses of single arterioles are attenuated markedly after intestinal ischemia, endotoxemia and traumatic shock: possible role of endothelial cells.	there is at present no agreement as to why several organs in the body are often compromised very early after either blood and fluid loss or sepsis. close inspection (utilizing electron microscopy) usually reveals that a great many of the endothelial cells (ec) are either destroyed, transformed, or have undergone morphological changes. since: the intimal lining of blood vessels, i.e., ec, may be important in mediating vasodilator substances and mechanisms; and early in shock and trauma, the perip ...	1985	3915339
salmonella vertebral osteomyelitis and epidural abscess in a child with sickle cell anemia.	a case of salmonella vertebral osteomyelitis with epidural abscess in a child with sickle cell anemia is presented. spinal osteomyelitis is a rare event in children. although osteomyelitis in sickle cell anemia may occur in any bone, it has most often been documented as beginning in the medullary cavity of the long and tubular bones. this is in contrast to the clinical presentation of osteomyelitis in the normal individual, who is likely to have infection beginning in and restricted to the metap ...	1985	3916460
the bacteriolytic action of mt-141, a new cephamycin antibiotic, on gram-negative bacteria.	mt-141, a new cephamycin (7 alpha-methoxy-cephalosporin) antibiotic with a d-cysteine moiety in its 7 beta-side chain, has binding affinities to penicillin-binding proteins of escherichia coli and an inhibitory action on their transpeptidase activity similar to those of other structurally related cephamycins. yet this antibiotic was found to exert an exceedingly strong and rapid lytic action on sensitive gram-negative bacteria such as e. coli, klebsiella pneumoniae, serratia marcescens and salmo ...	1985	3920178
properties of human anti-lipopolysaccharide gamma globulin: specificity and protective effects.	blood donated to the natal blood transfusion service was screened by an enzyme-linked immunosorbent assay (elisa) for anti-lipopolysaccharide (anti-lps) antibodies. plasma units with high concentrations (greater than 40 micrograms/ml) of anti-lps igg were pooled and fractionated to obtain a gamma globulin (lot lg-1). the binding of lg-1 antibodies to lps prepared from 14 bacterial species and strains was found to be the highest to lps from shigella flexneri, salmonella abortus equi and salmonell ...	1985	3922117
the diagnostic utility of the febrile agglutinin tests.	the purpose of our study was to analyze the use of febrile agglutinin (fa) serologic tests in the diagnosis of salmonella (typhi and paratyphi), rickettsia, brucella, and francisella infections. data were collected in a retrospective chart study of 202 titer requests covering a 42-month period at our teaching hospital. we found that no diagnoses were made by utilizing complete six-antigen fa panels. three cases of infection were diagnosed serologically, all three with more discriminately selecte ...	1985	3927019
release of galactosyltransferase from peritoneal macrophages during acute inflammation.	peritoneal cells harvested from mice injected with salmonella enteritidis or thioglycollate released large amounts of galactosyltransferase (gt), but not sialyltransferase, into their culture supernatants. maximum release of gt (using ovalbumin as acceptor) occurred from cells harvested 2-4 days after primary injection, but little gt was released from cells elicited by a secondary injection of salmonella or ovalbumin in sensitised mice or during intraperitoneal allogeneic reactions. enzyme relea ...	1985	3930517
relapse following cessation of antibiotic therapy for mouse typhoid in resistant and susceptible mice infected with salmonellae of differing virulence.	relapse after cessation of ampicillin therapy in inbred mice infected with salmonellae was studied. the incidence of relapse was influenced by the following. (a) the mouse strain, with gentically susceptible animals more likely to relapse than genetically resistant animals; a possible role for the ity gene was observed. (b) the virulence of the infecting organism, with a more virulent strain causing relapse in both resistant and susceptible mice, a less virulent strain causing relapse in neither ...	1985	3930625
turkey-associated salmonellosis at an elementary school--georgia.		1985	3932836
modulation of in vitro natural cell-mediated activity against enteropathogenic bacteria by simple sugars.	lymphoid cells from mouse peyer's patches and spleens were tested in a 2-h in vitro assay for their natural activity against the enteropathogenic bacteria salmonella typhimurium, salmonella enteritidis, salmonella tel aviv, and shigella sp. x16. the antibacterial activity expressed by normal cells was detected against all the bacterial strains tested with the exception of peyer's patch lymphocytes against s. tel aviv and splenocytes against shigella sp. x16. to determine whether the different ex ...	1985	3967926
exchange transfusions in rats with a perfluorated blood substitute: effect on thromboxane b2 levels during endotoxemia.	the effect of exchange transfusion with the perfluorated blood substitute (fluosol-43) on endotoxin-induced synthesis of immunoreactive (i) thromboxane (tx)b2, the stable metabolite of txa2, was investigated in rats. fluosol-43 was infused via the femoral vein with matched, incremental blood withdrawal from the carotid artery. blood was replaced with fluosol-43 to a final hematocrit of less than 3% in anesthetized rats maintained on 95% o2 and 5% co2. circulating platelet counts were reduced fro ...	1985	3978769
a role for the spleen in the appearance of igm in the bile of rats injected intravenously with horse erythrocytes.	the i.v. injection of the particulate antigens horse red blood cells (hrbc) and salmonella enteritidis into rats results in the appearance of high levels of igm agglutinating antibody in the serum and bile. this is in contrast to the appearance of specific iga antibodies in bile after the injection of antigen into the peyer's patches. at the height of the response, a fivefold to 10-fold increase in total igm was found in bile, whereas there was no increase in iga or in total protein levels. the ...	1985	3998463
the frequency of salmonellae on duck eggs.	total plate counts on washed duck eggs from a breeder farm on long island were less than 30/shell during the winter (january to february) of 1982. clean unwashed eggs had counts less than 9 x 10(1)/shell, whereas dirty unwashed eggs had counts as high as 9 x 10(5)/shell. our results showed that washing with a chlorine sanitizer (under commercial conditions) was highly effective in reducing surface bacterial counts on egg shells. prolonged storage reduced bacterial counts on clean eggs, but it di ...	1985	4001051
immunoglobulin m and immunoglobulin g responses in balb/c mice to conjugated outer membrane extracts of four salmonella serotypes.	outer membranes (oms) of salmonella enteritidis, s. anatum, s. typhimurium, and s. infantis were extracted and cross-linked with glutaraldehyde to form a large macromolecular antigen. the antigen consisted of om proteins and lipopolysaccharide and was designated 4-omp-lps. polyacrylamide gel electrophoresis of extracted oms from each serotype revealed differences in protein profiles. s. enteritidis and s. infantis possessed a greater variety of proteins than did s. anatum and s. typhimurium. imm ...	1985	4030094
increased myocardial contractility during endotoxin shock in dogs.	the slope of the left ventricular (lv) end-systolic pressure-diameter relationship (ees) was analyzed in open-chest, pentobarbital-anesthetized dogs before and after endotoxin administration. a lead ii electrocardiogram, systemic arterial pressure, lv pressure, lv dp/dt, and lv minor axis diameter were measured. after control measurements were taken, dogs were given either 1 mg/kg salmonella enteritidis endotoxin (n = 5) or an equivalent volume of saline (n = 4). control dogs were followed for 2 ...	1985	4051010
local transfer of delayed-type hypersensitivity after salmonella infection in mice.	an adoptive local transfer system has been used to study the mediators of delayed-type hypersensitivity induced in mice by infection with salmonella enteritidis 11rx. the cells which transfer this state of hypersensitivity to untreated recipients are nonadherent t lymphocytes with the surface phenotype lyt 1+2-, and successful transfer requires compatibility at the i-a subregion of the h-2 complex. in these and other respects these cells are indistinguishable from those previously found to be re ...	1985	4066031
bacterial isolates from nsukka meat market: a zoonotic appraisal.	swabs collected from butchers hands, knives, tables and meat displayed for sale at nsukka meat market showed that every item screened was contaminated. bacteria isolated include streptococcus faecalis, coagulase positive staphylococcus, clostridium perfringens, brucella species, corynebacterium haemolyticum, proteus mirabilis, p. vulgaris, escherichia coli, salmonella enteritidis, enterobacter aerogenes, pseudomonas multophilia, p. rubescens and beta-haemolytic streptococci. the zoonotic or publ ...	1985	4077409
experimental endotoxemia in the rat: efficacy of prostacyclin or the prostacyclin analog iloprost.	the purpose of this study was to examine the effects of pgi2 and iloprost, a prostacyclin analog, on the sequelae of experimental endotoxic shock. endotoxemia was produced in rats by iv injection of 20 mg/kg salmonella enteritidis (lps). mean arterial blood pressure fell from 117 +/- 5 mmhg (n = 22) to 92 +/- 5 mmhg and 71 +/- 10 mmhg at 30 and 180 min post-lps, respectively. in lps vehicle-treated rats, blood glucose levels fell from 100 +/- 10 mg/dl to 36 +/- 8 mg/dl at 180 min. plasma glutama ...	1985	2414027
enhancement of antigonadotropin response to the beta-subunit of ovine luteinizing hormone by carrier conjugation and combination with the beta-subunit of human chorionic gonadotropin.	previous studies have demonstrated the control of fertility in monkeys on immunization with the beta subunit of ovine luteinizing hormone (beta-olh) along with freund's complete adjuvant (cfa). an eventual birth control vaccine would demand immunization without cfa. beta-olh linked to tetanus toxoid (tt) adsorbed on alum-induced antibody response in bonnet monkeys with detoxified sodium phthalyl derivative of salmonella enteritidis lipopolysaccharide added only in the first injection. the antibo ...	1986	2424791
improvement in organ blood flow by inhibition of thromboxane synthetase during experimental endotoxic shock in the rat.	endotoxic shock is associated with increased metabolism of arachidonic acid to thromboxane (tx) and prostaglandins. this investigation examined the effects of two structurally dissimilar inhibitors of (tx) synthetase on salmonella enteritidis endotoxin (lps) (15 mg/kg)-induced alterations in cardiac output and organ blood flow in long-evans rats. an imidazole derivative, 7(1-imidazolyl) heptanoic acid (7-iha), and sodium -(e)-3-[4-(3-pyridyl-methyl)phenyl]-2-methacrylate (oky-1581) were injected ...	1986	2425166
[effect of the cultivation temperature on the production of biomass and lipopolysaccharide as well as the chemical composition and antigenicity of the lipopolysaccharide of s-forms and r-mutants of the genus salmonella].	the effect of different temperatures (30 to 43 degrees c) on salmonella s forms and r mutants in fermentor mass cultures was studied. it was found that for the velocity of substrate utilization, for maximum lps biosynthesis as well as for maximum biosynthesis of bacterial cell-mass the respective optimum temperature was different. in the case of s-form strains and of one sr mutant a cultivation temperature of 34 degrees c proved optimum for maximum yield of lps. at this temperature the yield of ...	1986	2426871
alterations in cellular ca2+ regulation in the liver in endotoxic shock.	effects of salmonella enteritidis endotoxin on cellular ca2+ regulation were studied in the liver. rats were given intravenous injections of saline (control) or endotoxin (15 mg/kg). they were killed 5 h later, at which time endotoxin-injected rats showed signs of shock. liver slices were used to measure ca2+ efflux from the intracellular ca2+ pool and the size of that pool. 45ca uptake was measured in isolated endoplasmic reticulum (er) from livers. 45ca efflux and uptake were also measured in ...	1986	3706573
thermoregulatory and acute-phase responses to endotoxin of full- term-pregnant rabbits.	fever, a fall in the plasma level of iron (fe), and rises in the levels of certain plasma glycoproteins (indexed by protein-bound-n-acetylneuraminic acid [nana]) normally occur during infection; they are thought to be mutually enhancing in host defense. it has been reported that fever is suppressed at full term of pregnancy; however, it is not known whether the blood chemical changes are similarly affected. also, the mechanism for the suppression of fever is controversial. since uteroplacental b ...	1986	3710977
effect of endotoxic shock on kinetics of system a amino acid transport in rat soleus muscle.	this study evaluated the kinetics of system a amino acid transport in soleus muscle during endotoxic shock. fasted male rats (80-100 g) were killed by decapitation 5 h after the intravenous injection of saline (control) or 20 mg/kg salmonella enteritidis endotoxin. soleus muscles (40 mg) from control or endotoxic rats were incubated in oxygenated krebs-ringer-bicarbonate buffer (ph 7.4) at 37 degrees c for 20, 40, or 60 min. initial rates of entry of alpha-aminoisobutyric acid (aib) into the inu ...	1986	3728705
meningitis and septicaemia in adults splenectomized for hodgkin's disease.	splenectomized and asplenic persons are at risk of developing sudden episodes of meningitis and/or septicaemia, frequently due to streptococcus pneumoniae (overwhelming postsplenectomy infection, or opsi). the application of staging splenectomy to patients with hodgkin's disease (hd) generated a new population at risk for opsi. we reviewed the cases of sudden meningitis and/or septicaemia in a series of 491 consecutive adults with hd. no case was recorded among 149 non-splenectomized patients. 6 ...	1986	3738430
the relative role of paf-acether and icosanoids in septic shock.	endotoxemia and gram negative sepsis remain a clinically important problem since mortality rate is still high in these diseases. recently, the participation of some new potential mediators in this pathology is beginning to be demonstrated but the results obtained on animal models with specific inhibitors are contradictory. in order to clarify the pathological importance of icosanoids and paf-acether in the septicemic process, we investigated the effects of indomethacin (ind) a cyclooxygenase inh ...	1986	3774851
evaluation of imipenem/cilastatin against nosocomial infections and multiresistant pathogens.	thirty-five patients suffering from soft tissue infections (12), upper utis (6), bronchopneumonia (6), septicaemia (2), chronic osteomyelitis (2), intra-abdominal abscess (2), liver abscess (1), lung abscess (1), acute cholangitis (1), thoracic empyema (1) and chronic prostatitis (1) were given imipenem/cilastatin for 6-21 days. in 22 patients several aggravating factors coexisted, while infection in 16 patients was polymicrobial. the following pathogens were implicated: pseudomonas aeruginosa ( ...	1986	3469191
oral ciprofloxacin therapy of infection caused by multiply resistant bacteria other than pseudomonas aeruginosa.	of 125 patients treated with ciprofloxacin at the columbia-presbyterian medical center, new york, 34 had infections due to bacteria other than pseudomonas aeruginosa. the mean age of the patients was 50 years (19-88 years) and most had significant underlying disease. there were nine lower respiratory infections, eight urinary tract infections, eight soft tissue infections, three osteomyelitis, and three intra-abdominal infections. the pathogens were: escherichia coli, 7 (mean mic 0.07 mg/l); ser ...	1986	3804906
evaluation of a commercial beta-glucuronidase test for the rapid and economical identification of escherichia coli.	a commercial beta-glucuronidase (beta-gur) test for the rapid and economical identification of escherichia coli was evaluated. a total of 762 clinical strains and 228 environmental isolates were studied. more than 95% of the e. coli strains were found to be beta-gur positive. thirty-one clinical isolates of shigella sonnei, 10 of enterobacter cloacae, eight of enterobacter aerogenes, nine of citrobacter freundii and one of salmonella enteritidis also gave positive results. the enzyme beta-gur wa ...	1986	3549665
analysis of 6-keto pgf1 alpha, 5-hete, and ltc4 in rat lung: comparison of gm/ms, ria, and eia.	the recent availability of fast and sensitive radioimmunoassay (ria) and enzyme immunoassay (eia) procedures to measure icosanoids has led to utilization of these techniques by many investigators. a major concern has been that techniques based on immunoreactivity may lack specificity, in particular if complex biologic fluids or tissue extracts are evaluated. the purpose of this investigation was the comparison of icosanoid measurements obtained either with eia or ria with those obtained by gas c ...	1986	3550900
[microcalorimetric study of salmonella].	we investigated the heat production of 42 different salmonella strains belonging to the serogroups a, b, c, d and e. using columbia- and brain heart infusion broth as growth media, we found 3 different types of heat profiles. salmonella typhi and salmonella choleraesuis showed thermograms which differed in shape from the remaining serotypes. the thermograms of one salmonella dublin isolate which showed an atypical biochemical behaviour could not be put into proper relation to one of these 3 micr ...	1986	3541456
[effect of dexamethasone-a synthetic glucocorticoid hormone on the immune response in pigs].	these experiments were designed to study the effects of a synthetic drug--dexamethasone (dex) on the immune response of weaned pigs against viral antigen (hog cholera vaccine) and bacterial antigen (formalin inactivated salmonella enteritis vaccine). twenty-three five-week-old pigs were divided into eight groups, six of which were injected twice daily with dex at 1.0 mg or 0.1 mg per kg of body weight for either four or five days. the other two groups served as controls. during this period, the ...	1986	3545702
[appendicitis in salmonella enteritidis food poisoning].		1986	3547360
[evaluation of bacteriologic cure of s. enteritidis infection in children based on 3- and 7-culture methods of feces control].		1986	3554373
salmonella serotypes from animals in new york state, 1978-1983.	the salmonella serotypes isolated during 1978 to 1983 at the diagnostic and clinical laboratories of the new york state college of veterinary medicine from animal sources in new york state were reviewed and compared to earlier data from new york state animals and to national data for both human and animal sources. a total of 255 salmonella strains were studied from the six year period and included 33 serotypes. salmonella enteritidis ser typhimurium continued to be the most commonly reported ser ...	1986	3940747
conservation of dna sequences for plasmid-mediated citrate utilization within the enterobacteria.	southern blot dna-dna hybridization experiments with a cloned cit+ dna fragment as a probe showed that the plasmid-mediated cit+ determinants from four cit plasmids (r726, poh3001, poh3035, and poh30221) were all homologous. sequences homologous to the plasmid-borne cit+ gene were also found in total bacterial dna isolated from salmonella paratyphi b, salmonella enteritidis, salmonella typhimurium lt-2, citrobacter freundii, atcc 8090, citrobacter amalonaticus atcc 25405, klebsiella pneumoniae i ...	1986	3941048
[report of an outbreak of invasive amebiasis in children at a camp for victims of the chichonal volcano].		1986	3296985
salmonella osteomyelitis after internal fixation of fracture.	a patient with salmonella group d (salmonella enteritidis) acute osteomyelitis of an operated femur is described. the patient failed to respond to chloramphenicol therapy and aztreonam therapy. the local infection that complicated the presence of a foreign body was eradicated only with the removal of the foreign body, an internal fixation plate.	1986	3331005
a survey of free-living falconiform birds for salmonella.	of 105 migrating falconiform birds of 7 species examined for salmonella shedding in new jersey, 2 (1.9%) were positive for salmonella spp. both positive birds were immature red-tailed hawks (buteo jamaicensis). salmonella enteritidis and s newport were the serotypes isolated. neither serotype expressed multiple resistance when tested against a panel of 12 antimicrobial drugs.	1986	3506002
human myeloid precursor cells do not possess or produce procoagulant activity (pca).	the procoagulant cellular activity (pca) of human myeloid precursor cells was evaluated after fractionation of normal bone marrow cells over a discontinuous albumin density gradient. no pca was documented in any of the six freshly isolated fractions (f1-f6); significant amounts of pca were instead produced, after a 4-h endotoxin preincubation, in fractions f1 and f2, which, unlike the other fractions, contained up to 5% monocyte-macrophages. after removal of the latter by plastic adherence, the ...	1986	3510892
kinin generation in the gingival inflammatory response to topically applied bacterial lipopolysaccharides.	a water-soluble lipopolysaccharide from salmonella enteritidis and a phenol-soluble lipopolysaccharide from leptotrichia buccalis were applied topically to the healthy marginal gingivae of beagle dogs. saline was applied to contralateral areas as an internal control. increases in vascular permeability were monitored by measurement of gingival fluid, and the collected gingival fluid samples were assayed for kininogenase and kinin activities. both lipopolysaccharides induced an inflammatory respon ...	1986	3511110
kinetics of macrophage recruitment and turnover in peritoneal inflammatory exudates induced by salmonella or thioglycollate broth.	kinetics of peritoneal macrophage turnover during infection of mice with salmonella enteritidis or following injection with thioglycollate broth or other peritoneal stimulants has been studied. single intravenous injections of tritiated thymidine were given and the cells were examined by autoradiography. maximum labelling of small adherent peritoneal macrophages occurred when 3h-thymidine was given 1 d after salmonella and the cells were harvested 1 d later. labelled cells decreased at later tim ...	1986	3512751
salmonella focal intracranial infections: review of the world literature (1884-1984) and report of an unusual case.	focal intracranial infections are unusual manifestations of salmonellosis. forty-three such infections have been reported in the world literature. the clinical data for 34 well-documented cases are reviewed. eleven patients had brain abscess, 19 had subdural empyema, three had epidural abscess, and one had both subdural empyema and brain abscess. brain abscess occurred more often in adults; in contrast, subdural empyema presented more often in children. fever, signs and symptoms of increased int ...	1986	3513285
in vivo inhibition of plasma protein leakage and salmonella enteritidis-induced mortality in the rat by a specific paf-acether antagonist: bn 52021.	the effects of bn 52021, a new specific paf-acether receptor antagonist and the total ginkgo biloba extract (gbe 761) from which this product was isolated, were studied in the rat on paf-acether-induced permeability and cell number changes and on endotoxin-induced lethality. their activities were compared to those of cyclooxygenase, 5-lipoxygenase and phospholipase a2 inhibitors. bn 52021 given s.c. or orally exerted a dose-related inhibition of paf-acether deleterious effects as well as of endo ...	1986	3515870
salmonella enteritidis. a rare cause of pyelonephritis in children.	a previously healthy 2.5-year-old boy developed symptoms of acute pyelonephritis following an acute gastroenteritis. the patient received parenteral ampicillin and gentamicin for 72 hours and then ampicillin for an additional 11 days when the original urine and stool cultures grew salmonella enteritidis, sensitive to ampicillin. the patient responded very well to treatment, but b-mode renal ultrasonogram revealed a left hydronephrosis and megaureter suggestive of longstanding obstruction of the ...	1986	3516508
[erythema nodosum associated with salmonella enteritidis gastroenteritis].		1986	3517982
prevention of traveler's diarrhea by the tablet form of bismuth subsalicylate.	in a randomized double-blind study, swiss adults traveling to tropical countries for 12 to 28 days took a solid formulation of bismuth subsalicylate (1.05 or 2.1 g/day on a twice-daily regimen) or placebo. efficacy was evaluated in 231 volunteers. diarrheal incidence was reduced by 41% in persons taking the high dose (p = 0.007) and by 35% in those taking the low dose (p = 0.03) with excellent compliance. no serious adverse reactions occurred, but objectionable taste, constipation, and nausea we ...	1986	3518624
effects of splenectomy on the retention of salmonella enteritidis and on the hemopoietic response to salmonella infection.	salmonella infection induces a marked increase in the splenic granulopoiesis, but causes a reduction in hemopoiesis in the bone marrow. in this study, effects of salmonella enteritidis infection on hemopoietic stem cells were examined in splenectomized (sx-) mice. splenectomy emphasized hemopoietic damage in the bone marrow caused by salmonella infection. total nucleated cells, pluripotent stem cells (cfus) and granulocyte-macrophage progenitor cells (gm-cfc) in the bone marrow of sx-mice all de ...	1986	3518829
autonomic thermoregulation after separation of the preoptic area from the hypothalamus in rats.	to clarify the role of the hypothalamic preoptic area in autonomic thermoregulation, the preoptic area (poa) of rats was disconnected from the rest of the brain-stem by bilateral microknife cuts which spared or included the medial forebrain bundle. the animals' metabolic responses to exogenous norepinephrine (0.5 mg/kg, im) were then measured at ambient temperatures of 25 degrees and 15 degrees c. oxygen uptake and colonic and tail skin temperatures were also measured at ambient temperatures of ...	1986	3520477
trimethoprim-sulfamethoxazole treatment of cholangitis complicating congenital hepatic fibrosis.		1986	3523453
synergistic toxicity of endotoxin and hemoglobin.	stroma-free hemoglobin (sfh) is advocated as an oxygen-transporting resuscitation solution. hemoglobin has been shown to enhance endotoxin lethality when given intraperitoneally. it is possible that sfh could interact with endotoxin when used as an oxygen-transporting resuscitation system for trauma victims with contaminating wounds. to assess the effects of these two agents when given intravascularly, rabbits were infused with sfh (1.75 gm/kg) or albumin (controls; 1.75 gm/kg) with and without ...	1986	3525717
[salmonella enteritidis arteritis].		1986	3526009
[rapid positive bacteriological diagnosis in toxic food poisoning].		1986	3526515
left ventricular function during lethal and sublethal endotoxemia in swine.	our previous studies suggested that after a median lethal dose (ld50) of endotoxin, cardiac contractility was depressed in nonsurviving dogs. the canine cardiovascular system is unlike humans in that dogs have a hepatic vein sphincter that is susceptible to adrenergic stimulation capable of raising hepatic and splanchnic venous pressures. we retested the hypothesis that lethality after endotoxin administration is associated with cardiac contractile depression in pigs, because the hepatic circula ...	1986	3526928
oral immunization of mice with attenuated salmonella enteritidis containing a recombinant plasmid which codes for production of the b subunit of heat-labile escherichia coli enterotoxin.	we used salmonella enteritidis serotype dublin strain sl1438, a nonreverting, aromatic-dependent, histidine-requiring mutant, as a recipient for a recombinant plasmid coding for production of the nontoxic b subunit of the heat-labile escherichia coli enterotoxin. the s. enteritidis derivative el23 produced heat-labile enterotoxin subunit b that was indistinguishable from heat-labile enterotoxin subunit b produced by strains of e. coli or salmonella typhi harboring the same plasmid. mice immunize ...	1986	3527989
[method for quantifying live bacteria in murine peritoneal macrophages by solubilizing with triton x-100].		1986	3528557
[a case of salmonella enteritidis hemopyrothorax].		1986	3528600
changing etiology and outcome of neonatal septicemia in riyadh, saudi arabia.	to study the etiology of neonatal septicemia and factors associated with outcome, all charts of neonates with bacteremia and clinical sepsis admitted to a neonatal unit in saudi arabia, from 1 november 1980 to 31 october 1984 were reviewed. the results were compared to a previous study period in the unit (1 november 1976-31 october 1980). septicemia was diagnosed on 50 occasions in 49 neonates. the incidence of neonatal sepsis among patients born in the hospital was 2.5/1,000 live births. mortal ...	1986	3529808
reactive arthropathy (reiter's syndrome) after salmonellosis: report of two cases and review of the literature.		1986	3531109
characterization of se1, a new general transducing phage of salmonella typhimurium.	a transducing phage, se1, which is able to infect salmonella typhimurium was isolated from a salmonella enteritidis strain. se1 is a temperate phage which is heteroimmune with respect to phages p22, l, kb1 and es18. it is similar in morphology and size to phages p22, l and kb1 and is serologically related to phages p22 and l but not to kb1. efficiencies of generalized transduction effected by phage se1 are similar to those for p22ht (int7), a mutant which mediates a high frequency of chromosomal ...	1986	3531393
salmonella in sewage effluent and the relationship to animal and human disease in the north of scotland.	during the period july 1982 to december 1984, the presence of salmonella organisms was investigated at weekly intervals in the sewage system and abattoir effluent of a town in the north of scotland. three hundred and fifteen isolations, representing 37 different serotypes, were made which included 20 different salmonella typhimurium phage types and four different s enteritidis phage types. ten of the serotypes were isolated from livestock in the district during the survey as well as in the perio ...	1986	3532507
salmonella perinephric abscess.		1986	3533198
the in vitro effects of salmonella enteriditis on urinary stone formation.	salmonella enteriditis has been previously found to have both unique inhibiting and augmenting properties on urinary stone formation. a series of in vitro experiments were performed in order to determine if the in vivo results could be explained in an in vitro model. urinary phosphorus was measured before and after incubation with various bacteria, and was found to increase significantly when incubated with s. enteriditis (p less than 0.05). urinary citrate was measured in a similar fashion foll ...	1986	3534306
endotoxin increases pulmonary vascular protein permeability in the dog.	endotoxin increases pulmonary vascular permeability consistently in some species but fails to reliably cause injury in the dog. we wondered whether this phenomenon depended on the method of injury assessment, as others have relied on edema measurement; we quantified injury by monitoring the rate of extravascular protein accumulation. 113min-labeled protein and 99mtc-labeled erythrocytes were injected into anesthetized dogs and monitored by an externally placed lung probe. a protein leak index, t ...	1986	3536835
[reactive pericarditis associated with salmonella gastroenteritis].		1986	3537566
[ acute non-calculous salmonella enteriditis cholecystitis, diagnosis by percutaneous puncture].		1986	3537571
the serum bactericidal and opsonizing defect in sickle cell anaemia: restoration of activity by control serum.	thirty-eight homozygous sickler sera were compared with a large pool of serum from healthy african non-sicklers with regard to bactericidal and phagocytic indices. one third of the sera showed reduced bactericidal activity against salmonella enteritidis which was restored by the addition of 4% control serum; control serum provided both heat-labile (hl) and absorbable (abs) serum factors. 76% of test sera showed greatly defective opsonization as indicated by ingestion by normal human neutrophils. ...	1986	3538524
curative properties of muramyl dipeptide in experimental naegleria meningoencephalitis.	naegleria fowleri is a free-living amoeba which causes a fatal meningoencephalitis in man. mice injected with the immunostimulant mdp or an attenuated 11rx strain of salmonella enteritidis showed some resistance to an intranasal challenge with n. fowleri. in addition it was observed that some of the mice infected with n. fowleri and showing symptoms of naegleria meningoencephalitis, given a single injection of mdp were cured of this disease. our findings suggest that the use of immunostimulants ...	1986	3538525
purification and characterization of fimbriae from salmonella enteritidis.	a human isolate of salmonella enteritidis which displayed strong pellicle formation during static broth culture and mannose-sensitive hemagglutination produced fimbriae which were morphologically indistinguishable from type 1 fimbriae of members of the family enterobacteriaceae. fimbrin was purified to homogeneity, and the apparent molecular weight (mr, 14,400) was markedly lower than that reported for the type 1 fimbrin of salmonella typhimurium (mr, 22,100). this fimbrin contained 40% hydropho ...	1986	2875990
differential regulation of effector responses of cell mediated immunity in experimental salmonellosis.	delayed type hypersensitivity (dth) and protective cell mediated immunity showed different profiles with respect to time following intraperitoneal immunization with live salmonella enteritidis. whereas the dth response decreased with time the protection index increased. the decline in dth response was found to be associated with suppressor cells generated by intraperitoneal immunization and could be prevented by cyclophosphamide treatment prior to immunization. it was concluded that the two effe ...	1986	2938854
augmented induction of interferons during listeria monocytogenes infection.	mice infected iv with an immunizing dose of the gram-positive bacterium, listeria monocytogenes, produced circulating interferon (ifn) during the inductive phase of the immune response to listeria. listeria infection also dramatically altered the host's responsiveness to ifn-inducing agents. within 24 hr of infection, mice acquired a 50-fold greater than normal capacity to produce the ifn alpha and/or ifn beta classes (ifn alpha/beta) following iv injection of endotoxin. serum levels of ifn alph ...	1986	3084667
cross-reactions in cell-mediated immunity to salmonella causing enteric fever.	cross-reactivity in a delayed-type hypersensitivity (dh) response was studied in mice immunised with live salmonella typhi, s. paratyphi a and s. paratyphi b. extensive cross-reactions outside the serogroup limits were observed. the ability of dh cross-reacting and non-cross-reacting sonicates to generate activated macrophages was studied in mice immunised 3 months earlier with s. paratyphi b. whereas dh cross-reacting s. poona sonicate generated activated macrophages the non-cross-reacting s. t ...	1986	3084790
influence of salmonella and other gram-negative bacteria on the survival of mice infected with schistosoma japonicum.		1986	3086463
[various salmonella serotypes isolated at a sewage purification plant in a large city over a one-year period].	the paper offers the results of a one-year-survey of salmonella-serotypes in a municipal sewage-purification plant with a capacity of roughly 70,000 m3 per day. findings of a quantitative study had shown salmonella-maxima in the activated-sludge-basin. this suggested specialized salmonella-serotypes, resident in this part of the plant as a possible explanation which was to be verified by this study. on ten days samples were taken from the inlet, and the outlet of the primary-sedimentation-tank, ...	1986	3087096
[effect against macrophages of purified spa of s. enteritidis].		1986	3093604
salmonellosis at a resort hotel--puerto rico.		1986	3099150
[interference of the intestinal ecosystem of mice in the oral administration of lyophilized live bacteria].	oral vaccines mode by living or killed bacteria are commonly used to restore normal intestinal flora; it's not well know, however, which bacteria play the leading part in this ecosystem. in the present paper authors have intended to compare the effectiveness of an oral vaccine, made by bifidobacterium bifidus and lactobacillus acidofilus, with another of similar use, made by enterococci, to increase the mouse resistance to lethal salmonella enteritidis infections. according to collected microbio ...	1986	3119409
cloned, random chromosomal sequences as probes to identify salmonella species.	we have developed and evaluated a new technique--chromosomal probe fingerprinting--to differentiate between strains of salmonella species by using sequences of cloned chromosomal dna as probes to highlight restriction site heterogeneity. chromosomal probe fingerprint patterns were compared with other strain-typing methods and epidemiological data. seventeen isolates of salmonella typhimurium recovered from 11 outbreaks had six unique chromosomal probe fingerprint patterns. most strains of salmon ...	1986	3011919
characteristics of myocardial beta-adrenergic receptors during endotoxicosis in the rat.	the effects of in vivo endotoxin administration on beta-adrenergic receptors in rat ventricle membranes were studied using [3h]dihydroalprenolol as a radioligand. nonlinear regression analysis of saturation binding indicated one-site binding of antagonist in both control and endotoxic tissues. there was no change in maximum binding or dissociation constant of [3h]dihydroalprenolol at 0.5 or 3 h after endotoxin administration or when the rats were in the agonal stage of shock. isoproterenol compe ...	1986	3017135
polymyxin-b inhibition of lps-induced interleukin-1 secretion by human monocytes is dependent upon the lps origin.	polymyxin-b (pmb) is an antibiotic known to inhibit various biological activities induced by lipopolysaccharides (lps). we have investigated the ability of pmb to inhibit lps-induced interleukin-1 (il-1) secretion by human monocytes in vitro. interleukin-1 was assayed by the conventional comitogenic assay using mice thymocytes. our data demonstrate that pmb (1-2 micrograms/assay)-mediated inhibition of lps-induced il-1 secretion depends on the origin of the lps. interleukin-1 secretions induced ...	1986	3023974
beneficial effects of a leukotriene antagonist on endotoxin-induced acute hemodynamic alterations.	the role of lipoxygenase metabolites of arachidonic acid as inflammatory mediators of endotoxin shock remains uncertain. in this study the effect of ly171883, a selective leukotriene d4/e4 antagonist, on the hemodynamic alterations of endotoxin shock was assessed. adult male rats were given an intraperitoneal injection of ly171883 (30 mg/kg) or vehicle 10 minutes prior to intravenous injection of endotoxin (15 mg/kg) or vehicle. cardiac output, mean arterial pressure, and multiple organ blood fl ...	1987	3038364
modulation of arachidonic acid metabolism in experimental arthritis induced by salmonella enteritidis. i. effect of ibuprofen and flurbiprofen on experimental arthritis induced by salmonella enteritidis.	oral administration of two nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, can suppress the salmonella-induced arthritis in rats. the joint swelling index of arthritic paws showed suppression of arthritis in animals treated with the drugs, this effect being greater with flurbiprofen. measurement of 5 eicosanoids in femoral vein plasma showed increase of arachidonic acid products in salmonella-treated rats. inhibition of joint inflammation resulting from treatment with ibuprofen ...	1987	3124133
survival of pathogenic bacteria in environmental microcosms.	the survival times of salmonella enteritidis, pseudomonas aeruginosa, staphylococcus aureus, and vibrio cholerae in natural soil and river water samples were monitored by using various differential media. s. aureus and v. cholerae failed to survive in samples of soil, groundwater, and river water with various degrees of eutrophication. the population of the introduced s. enteritidis remained fairly constant in all three samples of soils tested. in water samples, numbers of s. enteritidis and p. ...	1987	3130237
increasing rate of salmonella enteritidis infections in the northeastern united states.		1987	3099158
update: salmonella enteritidis infections in the northeastern united states.		1987	3104756
[plasmid profiles and antimicrobial resistance in salmonella typhimurium, s. enteritidis, and s. braenderup isolates from human sources].		1987	3112277
effect of diltiazem on intracellular ca2+ mobilization in hepatocytes during endotoxic shock.	effects of salmonella enteritidis endotoxin on intracellular ca2+ mobilization were studied in hepatocytes. rats were given intravenous injections of saline (control), endotoxin (20 mg/kg), or endotoxin (20 mg/kg) plus diltiazem (1.2 mg/kg). they were killed 5 h later, at which time endotoxin-injected rats showed signs of shock. the involvement of myoinositol 1,4,5-trisphosphate (ip3) and arachidonic acid (aa) in intracellular ca2+ mobilization was tested using saponin-permeabilized hepatocytes. ...	1987	3116862
the diagnostic value of fever patterns.		1987	3117810
[use of phage typing of salmonellae in the control of an epidemic in the south moravian region].		1987	2954662
effect of the thromboxane a2-receptor antagonists, sq 29,548 and sq 28,668, on the pulmonary hypertensive response to endotoxemia in swine.	the effects of two selective thromboxane (tx) a2 antagonists (sq 29,548 and sq 28,668) on endotoxin-induced pulmonary hypertension were determined in anesthetized pigs. sq 29,548 (10 micrograms/kg/min, i.v., n = 6) or vehicle (n = 7) was infused from 15 min before until 60 min after an intravenous infusion of salmonella enteritidis endotoxin (1.0 microgram/kg). within 20 min, vehicle-treated animals developed an acute 350 +/- 25% increase in pulmonary vascular resistance (pvr) with a 43% surviva ...	1987	2958886