Publications

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post-treatment 18f-fdg-pet/ct versus contrast-enhanced ct in patients with oropharyngeal squamous cell carcinoma: comparative effectiveness study.to compare the accuracy of same-day therapy-assessment pet/computed tomography (pet/ct) and conventional contrast-enhanced computed tomography (cect) in patients with oropharyngeal squamous cell carcinoma (opscc).201728099264
evaluation of the point-of-care becton dickinson veritorâ„¢ rapid influenza diagnostic test in kenya, 2013-2014.we evaluated the performance of the becton dickinson veritorâ„¢ system flu a + b rapid influenza diagnostic test (ridt) to detect influenza viruses in respiratory specimens from patients enrolled at five surveillance sites in kenya, a tropical country where influenza seasonality is variable.201728077093
periodic screening pelvic examination: evidence report and systematic review for the us preventive services task force.recent changes in the periodicity of cervical cancer screening have led to questions about the role of screening pelvic examinations among asymptomatic women.201728267861
an evidence synthesis approach to estimating the proportion of influenza among influenza-like illness patients.estimation of the national-level incidence of seasonal influenza is notoriously challenging. surveillance of influenza-like illness is carried out in many countries using a variety of data sources, and several methods have been developed to estimate influenza incidence. our aim was to obtain maximally informed estimates of the proportion of influenza-like illness that is true influenza using all available data.201728252453
experimental and computational surface hydrophobicity analysis of a non-enveloped virus and proteins.the physical characteristics of viruses needs to be understood in order to manipulate the interaction of viruses with host cells, as well as to create specific molecular recognition techniques to detect, purify, and remove viruses. viruses are generally believed to be positively charged at physiological ph, but there are few other defining characteristics. here, we have experimentally and computationally demonstrated that a non-enveloped virus is more hydrophobic than a panel of model proteins. ...201728219841
antiviral activity of a novel composition of peracetic acid disinfectant on parvoviruses.porcine parvoviruses (ppv) are known to be particularly resistant to many disinfectants used to control other non-enveloped viruses. however, effective disinfectants used against ppv are harsh and corrosive to animal health facilities and the environment. we propose a noncorrosive "green" disinfectant that generates peracetic acid in-situ and is capable of inactivating ppv completely at a 1% concentration for a 10-minute contact time.201728154460
new highly divergent plum pox virus isolates infecting sour cherry in russia.unusual plum pox virus (ppv) isolates (named tat isolates) were discovered on sour cherry (prunus cerasus) in russia. they failed to be recognized by rt-pcr using commonly employed primers specific to the strains c or cr (the only ones that proved able to infect sour cherry) as well as to the strains m and w. some of them can be detected by rt-pcr using the ppv-d-specific primers p1/pd or by tas-elisa with the ppv-c-specific monoclonal antibody ac. phylogenetic analysis of the 3'-terminal genomi ...201728006670
diagnosis and treatment of acute retinal necrosis: a report by the american academy of ophthalmology.to evaluate the available evidence in peer-reviewed publications about the diagnosis and treatment of acute retinal necrosis (arn).201728094044
non-invasive fibrosis score for hepatitis delta.identifying advanced fibrosis in chronic hepatitis delta patients and thus in need of urgent treatment is crucial. to avoid liver biopsy, non-invasive fibrosis scores may be helpful but have not been evaluated for chronic hepatitis delta yet.201727428078
neurosurgery and human immunodeficiency virus in the era of combination antiretroviral therapy: a review.human immunodeficiency virus (hiv) is a global health problem. it renders the central nervous system susceptible to infectious and noninfectious diseases. hiv-positive individuals may present to neurosurgical services with brain lesions of unknown etiology. the differential diagnosis in these cases is broad, including opportunistic infections and malignancies, and investigation should be tailored accordingly. opportunistic infections of the central nervous system can be complicated by hydrocepha ...201727081898
performance of point-of-care urine test in diagnosing tuberculosis suspects with and without hiv infection in selected peripheral health settings of addis ababa, ethiopia.there are few rapid point-of-care tests (poct) for tuberculosis (tb) for use in resource-constrained settings with high levels of human immunodeficiency virus (hiv). this hinders early tuberculosis (tb) treatment. this cross-sectional study evaluates the recently developed urine determine tuberculosis lipoarabinomannan (tb lam) antigen test. a total of 122 participants with signs and symptoms of tb, including 21 (17.1%) participants positive for hiv, were enrolled from september 2011 to march 20 ...201728137314
pathogen safety of a new intravenous immune globulin 10% liquid.the manufacturing process of a new intravenous immune globulin (ivig) 10% liquid product incorporates two dedicated pathogen safety steps: solvent/detergent (s/d) treatment and nanofiltration (20 nm). ion-exchange chromatography (iec) during protein purification also contributes to pathogen safety. the ability of these three process steps to inactivate/remove viruses and prions was evaluated.201728236170
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