Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| thymus transplantation. reconstitution of cellular immunity in a four-year-old patient with t-cell deficiency. | the case is reported of a 4-year-old girl affected with recurrent infections; anaemia, thrombocytopenia, haemorrhages and hepatosplenomegaly. immunological investigations revealed a defect in cellular immunity related to the thymus-dependent system, hypergammaglobulinaemia (especially of class ige), and very high titres of antibodies against epstein-barr virus (ebv). after foetal thymus transplantation, correction of the immunological defect and significant clinical improvement were noted, as we ... | 1975 | 171111 |
| nasopharyngeal carcinoma. ix. antibodies to ebna and correlation with response to other ebv antigens in chinese patients. | ninety-five sera from chinese npc patients in different stages of the disease, 38 sera from chinese patients with other cancers, and 50 normal chinese sera, were titrated for ebna, vca, ea and complement-fixing (cf/s) ebv-specific antibodies. the geometric mean (gmt) ebna antibody titre of patients with npc at stage i was found to be four times higher than that of normal individuals and increased in parallel with clinical deterioration. antibody titres against ebna did not correlate with either ... | 1975 | 171226 |
| human leukemia-associated antigens: detection on cells of established lymphoblastoid lines. | primate and rabbit antisera to different morphologic classes of human leukemia cells, after appropriate absorptions, detected leukemia-associated antigens present on cultured lymphoblastoid cell lines derived from leukemia patients. the primate antisera distinguished antigens on cells derived from myeloid leukemia patients from those on cells derived from lymphocytic leukemia patients. of particular interest was the fact that antigens of myeloid leukemia, but not of lymphatic leukemia, were dete ... | 1975 | 171308 |
| epidemiology of cytomegalovirus infection after transplantation and immunosuppression. | viral infections and clinical complications were studied during hemodialysis and after renal transplantation. active cytomegalovirus infection developed in 96% of patients after renal transplantation; reactivation of herpes simplex, varicella-zoster, and epstein-barr viruses was found in 35%, 24%, and 0% of patients, respectively. cytomegalovirus viremia developed in 42% of patients an average of two months after renal transplantation, lasted 1.75 (+/- 1.5) months (except in one patient with chr ... | 1975 | 171315 |
| direct visualization of enveloped epstein-barr herpesvirus in throat washing with leukocyte-transforming activity. | mature enveloped virions belonging to the herpes class were found in a concentrated, partially purified specimen of throat washings from a patient undergoing immunosuppressive therapy for prevention of renal homograft rejection. this throat washing contained a high titer of biologically active epstein-barr virus and no other human herpesviruses. epstein-barr virions were not detected in throat washings from patients with mononucleosis that had only low titers of transforming activity. | 1975 | 171319 |
| a prospective evaluation of heterophile and epstein-barr virus-specific igm antibody tests in clinical and subclinical infectious mononucleosis: specificity and sensitivity of the tests and persistence of antibody. | three heterophile antibody tests and a test specific for igm antibody to epstein-barr virus were evaluated during prospective studies of infectious mononucleosis. specificity was judged by the frequency of false-positive results in sera of known qualities taken before illness; except for two patients bled during early, unrecognized illnes,, titers of greater than or equal to 1:40 were detected in 12% by the absorbed sheep red cell test, in 6.7% by the absorbed horse red cell test, and in none by ... | 1975 | 171321 |
| suppression of spontaneous in vitro transformation of autologous leukocytes by plasma from convalescent and postconvalescent infectious mononucleosis patients. | all 14 plasma samples from 13 convalescent and postconvalescent infectious mononucleosis (im) patients suppressed the spontaneous in vitro transformation of autologous leukocytes. in contrast, only 2 of 8 plasma samples from patients with acute im suppressed this transformation. all 7 patients whose blood was tested both in the acute and convalescent or postconvalescent phases of im showed either a conversion in transformation suppression status from negative to positive or an increase in the st ... | 1975 | 171425 |
| amounts of epstein-barr virus dna in somatic cell hybrids between burkitt lymphoma-derived cell lines. | the amounts of epstein-barr virus dna in somatic cell hybrids between human lymphoid cell lines were found to be higher than in the parental cell lines, although the hybrids were not induced to spontaneous virus production. | 1975 | 171457 |
| cell-mediated immunity to epstein-barr-virus-transformed lymphoblastoid cells in acute infectious mononucleosis. | mononuclear peripheral blood leukocytes from 21 patients with infectious mononucleosis and 16 healthy controls were tested in a 51cr-release assay for cytotoxicity against two human lymphoblastoid cell lines derived from the same donor. one line contained the epstein-barr virus (ebv); the other did not. acute-phase leukocytes were significantly more cytotoxic against the ebv-infected cell line than were control leukocytes. mean (+/- s.e.) lysis at a leukocyte-target-cell ratio of 100:1 was 10.6 ... | 1975 | 171568 |
| hbs-ag-negative hepatitis in a hemodialysis unit: relation to epstein-barr virus. | eleven of 40 patients in a hemodialysis unit had clinical or biochemical evidence of hepatitis during a five-week period. the clinical disease was mild, being limited solely to dialysis patients. epidemiologic investigation indicated that the incubation period was between 17 and 35 days and that 10 of 11 patients had been exposed to a single venous-pressure monitor before onset. dried blood and evidence of blood reflux up the venous-pressure gauge suggested that cross-contamination of the blood ... | 1975 | 171573 |
| the epstein-barr virus and neoplasia. | 1975 | 171578 | |
| enhanced representation of hl-a antigens on human lymphocytes after mitogenesis induced by phytohemagglutinin or epstein-barr virus. | the amount of hl-a antigens present on the peripheral blood lymphocytes of a single human donor was increased about 11-fold after stimulation with phytohemagglutinin and 36-fold after transformation with epstein-barr virus. this increase applied to all four hl-a specificities of these cells. the response to phytohemagglutinin was dependent on dose and was first observed at 12 hr of incubation. measurements of the amount of surface membranes by geometry, by radioiodinatable surface proteins, and ... | 1975 | 171657 |
| comparison between growth characteristics of an epstein--barr virus (ebv)-genome-negative lymphoma line and its ebv-converted subline in vitro. | the gc-bjab cell line, which carries the epstein--barr virus (ebv), was derived from an ebv-genome-negative lymphoma line (bjab) by ebv infection in vitro [g. b. clements, g. klein, and s. povey (1975) int. j. cancer, in press]. both lines grow at a similar rate at 37 degrees but they differ at other temperatures. bjab grows well at 34 degrees, 37 degrees, and 39 degrees. gc-bjab grows at 37 degrees and 39 degrees, but grows poorly at 34 degrees. at 37 degrees, gc-bjab cultures can be maintained ... | 1975 | 171663 |
| growth of permanent lymphoid cell cultures from human source: tenth anniversary. | the authors developed 52 permanent lymphoid cell cultures from various human sources, mainly from neoplastic lymphoproliferative disease. these cultures are reviewed against the background of similar cultures obtained in several other laboratories. the peculiar features of these cultures are: 1) the phenomenon of lymphoblastoid transformation; 2) the production of both globulins and mediators of delayed hypersensitivity; 3) the presence of herpes type virus as related to etiology or autoimmunity ... | 1975 | 171791 |
| [genetic manipulation of eukaryotic cells]. | 1975 | 171811 | |
| [immunovirological factors in epitheliomas of the rhinopharynx]. | the epidemiology of nasopharyngeal carcinoma (npc) suggests the intervention of genetic factors. these factors may be represented by a specific hl-a pattern (leucocyte antigens) as found in chinese npc patients (deficit of antigens corresponding to the second sublocus and discovery of a new antigen, named sin-2). the association between npc and a herpesvirus (the ebv) is based on elevated antibodies against a variety of ebv coded antigens, on cell mediated immune reactions, and on the regular pr ... | 1975 | 172172 |
| antibodies to epstein-barr virus in patients with hodgkin's disease and leukemia. | sera from 67 hodgkin's disease patients, 71 leukemia patients, and 186 healthy subjects were tested for antibodies to epstein-barr (eb) viral antigens by immunofluorescence methods. in both disease categories, in particular hodgkin's disease patients, levels of antibodies to the viral capsid antigen (ebv-vca) and mgt were higher than in the healthy controls. significantly higher titers were found in jewish patients of asian-african origin, as compared to jews of european origin, with arab patien ... | 1975 | 172216 |
| [occult nasopharyngeal carcinoma (author's transl)]. | clinical and histological examination of a cervical lymph node, removed from a 15-year-old boy, revealed nasopharyngeal carcinoma as the probable diagnosis. but the decisive diagnostic pointer was a markedly raised epstein-barr virus antibody titre, which gives the diagnosis at a time when there may not as yet be clinical evidence of carcinoma. serial serum titre determinations are of prognostic value: with increasing spread of the tumour there is a rise in antibody titre. autopsy confirmed that ... | 1975 | 172307 |
| etiological spectrum of post-transfusion hepatitis. | frequent occurrence of post-transfusion hepatitis continues despite screening for australia antigen in blood before transfusion and elimination of commercial donor sources. the majority of these cases appears unrelated to hepatitis b virus. preoperative, acute, and convalescent serra were screened for evidence of hepatitis b, hepatitis a, epstein-barr, and cytomegalovirus exposure in 34 cardiac surgery patients developing post-transfusion hepatitis postoperatively. four patients showed evidence ... | 1975 | 172400 |
| origin of lymphoid lines established from mixed cultures of cord-blood lymphocytes and explants from infectious mononucleosis, burkitt lymphoma and healthy donors. | lymphocytes were explanted from ebv-seropositive donors including peripheral blood of infectious mononucleosis patients, healthy donors and ebv-genome-carrying cells from burkitt lymphoma (bl) biopsies or nude mouse-passaged, bl-biopsy-derived lines. the explanted cells were mixed with fresh cord-blood lymphocytes from mice of the opposite sex. in all categories of derived lines, cord-blood cell progeny was predominant, as judged by the sex marker and other associated markers. only one bl biopsy ... | 1975 | 172457 |
| sensitive method to detect non-complement-fixing antibodies to epstein-barr virus nuclear antigne. | the anti-complement immunofluorescence (acif) test was modified to detect non-complement-fixing antibodies to epstein-barr (eb) virus nuclear antigen (ibna). these ebna antibodies belong to the immunoglobulin classes iga and igg. in our method anti-human gamma-globulin (ahg) was bound to the ebna antibodies before the complement was added. if only non-complement-fixing antibodies are present the complement can be fixed to the ahg. within only a few weeks of the onset of infectious mononucleosis ... | 1975 | 172458 |
| spontaneous interferon production and epstein-barr virus antigen expression in two human lymphoid cell lines and their somatic cell hybrids. | two human lymphoid cell lines, raji and namalwa, and seven somatic cell hybrids between these two cells were tested for spontaneous interferon production. namalwa and three of the hybrids produce interferon while the four other hybrids, like raji, do not. though the namalwa line is relatively resistant to superinfection with the epstein-barr virus (ebv), all hybrids are as susceptible to ebv as the raji parent. high extracellular concentrations of interferon likewise had little effect on ebv sup ... | 1975 | 172473 |
| [clinical examination of eb virus infection (author's transl)]. | 1975 | 172670 | |
| absence of infectious epstein-barr virus in blood in acute infectious mononucleosis. | 1975 | 172793 | |
| persistence of cmv genome in lymphoid cells after congenital infection. | 1975 | 172796 | |
| growth and differentiation in culture of leukemic leukocytes from a patient with acute myelogenous leukemia and re-identification of type-c virus. | conditioned medium from a culture of whole human embryo cells stimulated prolonged exponential growth in suspension culture of leukocytes from a patient with acute myelogenous leukemia. ten to 20% of the cultured cells consistently differentiated into mature granulocytes including neutrophils, eosinophils, and basophils. the proportion of lymphocytes declined after culturing, and tests for epstein-barr virus antigens were negative. an abnormality of a g group chromosome was observed in some meta ... | 1975 | 172897 |
| epstein-barr herpesvirus and infectious mononucleosis. | 1975 | 172973 | |
| virologic studies in rheumatoid arthritis. | comparison of virus antibody titers in jra and matched controls failed to implicate rubella, measles, parainfluenza type 1 or epstein-barr viruses. neither rna viruses or mycoplasma were detected in rheumatoid synovial cell cultures by 3h-uridine incorporation. mycoplasma were not isolated from rheumatoid synovial membranes or cell cultures using the large specimen-broth culture procedure. the balance of available evidence, including our own, suggests that mycoplasma are not involved in ra. viru ... | 1975 | 173010 |
| stimulation of normal lymphocytes with autologous lymphoid cell lines: properties of derived killer cells. | lymphocytes from normal adults, with or without serological signs of previous epstein-barr virus (ebv) infection, could be stimulated to proliferate and produce killer cells by incubation with autologous ebv-genome-positive lymphoid cell lines (lcls). the stimulated cells were most probably of t-cell origin, although at the peak of stimulation many of them lacked the sheep erythrocyte marker. direct effector-target cell contact was necessary for lysis to occur. the cytotoxicity of autologously s ... | 1975 | 173017 |
| carcinoma of the nasopharynx in children. | seven children with carcinoma of the nasopharynx have been treated and followed for five years. in this group of patients there were no cranial nerve palsies or radiographic evidence of destruction of the base of the skull. four of the seven patients are living and well. the development of lymphoepithelioma in two siblings is of great interest from an environmental and genetic point of view. the older sibling developed the clinical manifestations of the tumor at 12 years of age and four years la ... | 1975 | 173235 |
| tubuloreticular structures in human lymphoid cell lines. a cell biological study. | human lymphoid cell lines were studied as an experimental model for the spontaneous or induced occurrence of tuburloreticular structures (trs). it was possible to induce trs after culturing the eb-3 cell line with 20 mug/ml bromodeoxyuridine (brudr) during 96 h. starvation, culturing at lower temperature (32 degrees) or inhibition of dna synthesis did not give rise to the production of trs. the response to brudr could be blocked with 60 mug/ml thymidine but not with 60 mug/ml deoxycytidine. the ... | 1975 | 173383 |
| letter: acute leukemia with burkitt's tumor cells. | 1975 | 173442 | |
| childhood hodgkin's disease in israel. a study of 17 cases. | a study of 17 children suffering from hodgkin's disease (h.d.) is presented. the special ethnic distribution with predominance in arab and oriental jewish children is noted. a high incidence of mixed cellularity histology in arab children is emphasized. a conservative approach to therapy, i.e. extended field regional radiotherapy only, resulted in a long first complete remission period in lymphocyte predominance and nodular sclerosis h.d. stages ia and iia. all children in stage iiib and iv were ... | 1975 | 173461 |
| anti-epstein-barr virus antibody in patients with cancer of various sites and control groups. | sera collected from patients with nasopharyngeal carcinoma (npc, 321 cases), cancer of the other sites (297 cases), diseases of the ear, nose and throat (64 cases) and neighborhood controls matched for age and sex (817 cases) were titrated for antibodies to epstein-barr virus (ebv) by the indirect immunofluorescence antibody technique. high anti-ebv antibody titers (greater than or equal to 1:640) were noted in 55% in patients with npc but only less than 31% were noted for the other 3 groups. th ... | 1975 | 173499 |
| an improved specific igm antibody assay for epstein-barr virus. | a new method for detecting specific igm antibodies to the epstein-barr virus using indirect fluorescence is presented. the procedure is simple and reproducible, and of great value for the diagnosis of an acute infection. the number of positive cells is higher than in the epstein-barr igg test. it would seem that it is possible to detect a positive igm-specific antigen with this new test. | 1975 | 173658 |
| epidemiologic study of a leukocyte-transforming agent in a general population. | studies by others have demonstrated a leukocyte-transforming agent(s) (lta) in the oropharyngeal secretions of a significant number of individuals with epstein-barr virus-associated infectious mononucleosis, cancer, and, to a lesser extent, an outpatient population. this present study determines by systematic sampling the prevalence of lta in 27 families of a semirural community. throat swab inoculums from three of 54 adults and none of 44 children induced transformation of umbilical cord lympho ... | 1975 | 173738 |
| [antibody to epstein-barr virus in head and neck tumors (author's transl)]. | 1975 | 173824 | |
| in vitro evaluation of cell-mediated immunity to epstein-barr herpesvirus by cell migration inhibition tests. | migration of peripheral leukocytes in samples from sensitized [epstein-barr virus (ebv) antibody-positive] humans was greatly inhibited when challenged by antigen prepared from ebv-producing p3hr-1 cells but not by antigen prepared from ebv-nonproducing raji cells, ebv-negative human fibroblasts, or epithelial cells. such inhibition was not observed when peripheral leuocytes from subjects or neonates not sensitized to ebv were challenged. similar results were obtained in a two-stage test when th ... | 1975 | 173867 |
| [juvenile tonsillectomy and leukemia]. | among 305 children with leukemia, between one and fourteen years old, authors found 8 and in a comparative group ("individual matched pairs") 40 children with removed tonsils. the difference (2.62% tonsillectomized children in the leukemia-group, 13.11% in the comparative group) is highly significant. the frequency of tonsillectomy in childhood in germany corresponds to the percentage of 13.11%. it has to be discussed, if there exists a causality between the state of the tonsils and the frequenc ... | 1975 | 173947 |
| letter: infectious mononucleosis, academic performance, and emotional stability. | 1975 | 46553 | |
| epstein-barr virus-induced transformation of human leukocytes after cell fractionation. | the efficiency of transformation of human lymphocytes after infection with epstein-barr virus (ebv) was determined in fractionated and non-fractionated preparations derived from 16 human cord blood samples and two blood samples from adult donors. the transformation efficiency of macrophage-depleted leukocytes was consistently lower as compared to non-fractionated leukocytes. additional depletion of b-cells resulted in a further decrease. reduction of t-cells, however, did not influence significa ... | 1975 | 47842 |
| infectious mononucleosis: model for self-limiting lymphoproliferation. | evidence for the extensive lymphoproliferation which characterises infectious mononucleosis (i.m.) is summarised, and some of the mechanisms which are though to control lymphoproliferative activity in this disease are discussed. the main host responses which appear to limit lymphoproliferation in i.m. include the development of humoral antibodies against the epstein-barr (e.b.) virus-associated membrane antigen (present on the e.b. viral envelope and on e.b.-virus-infected cells) and cellular im ... | 1975 | 48066 |
| x-linked recessive progressive combined variable immunodeficiency (duncan's disease). | of 18 boys in duncan kindred, 6 died of a lymphoproliferative disease. they exhibited a subtle, progressive combined variable immunodeficiency disease characterised by benign or malignant proliferation of lymphocytes, histiocytosis, and alterations in concentrations of serum-immunoglobulins. infectious mononucleosis occurred during or preceding terminal events in at least 3 of the cousins. fever, pharyngitis, lymphadenomegaly, hepatosplenomegaly, atypical lymphocytosis, and a spectrum ranging fr ... | 1975 | 48119 |
| lymphoblastoid transformation and kinetics of appearance of viral nuclear antigen (ebna) in cord-blood lymphocytes infected by epstein-barr virus (ebv). | human cord-blood lymphocytes were infected with b95.8 epstein-barr virus (ebv) before and after separation into b- and t-cell populations. lymphoblastoid cells exhibiting b-cell characteristics appeared after 2 to 3 days of culture in the total population and in the separated b-cell subpopulation but not in the t-cell subpopulation. ebv nuclear antigen (ebna) was detected concurrently with the appearance of lymphoblastoid cells. the proportion of ebna-positive cells corresponded to that of lymph ... | 1975 | 49325 |
| tumor viruses: 1974. | 1975 | 50896 | |
| the epstein-barr virus and malignancy: molecular evidence. | 1975 | 50897 | |
| hodgkin's disease. | 1975 | 51322 | |
| mononucleosis-associated subacute sclerosing panencephalitis. | three cases of coincidental infectious mononucleosis (i.m.) and subacute sclerosing panencephalitis (s.s.p.e.) in children are reported. in two of the cases, i.m. preceded the appearance of s.s.p.e. symptoms. the other case of s.s.p.e. was associated with apparent mononucleosis encephalitis. all three patients died within 3 months of s.s.p.e. being diagnosed and had pathological changes characteristic of that disease and raised levels of measles antibody. two of the patients had apparent t-cell- ... | 1975 | 51346 |
| clinical and serological analysis of transfusion-associated hepatitis. | of 108 prospectively followed, multiply transfused, open-heart-surgery patients, 12 (11%) developed hepatitis. patients received only volunteer donor blood tested for hepatitis-b surface antigen (hbsag) prior to transfusion by counterelectrophoresis (c.e.p.). 4 of the 12 patients developed hepatitis-b-virus infection. subsequent testing of donor serums by solid-phase radioimmunoassay (r.i.a.) revealed that an r.i.a.-positive, c.e.p.-negative blood unit was transfused to 3 of the 4 type-b hepatit ... | 1975 | 53329 |
| critical evaluation of b and t cell markers in man. | 1975 | 53874 | |
| comparison of dna polymerase activities from an american burkitt's lymphoma cell line and ebv producer and nonproducer cells. | 1975 | 65315 | |
| recent studies with eb virus. | 1975 | 174330 | |
| [use of demographic method for the study of adenoviruses and herpesviruses in a closed infants' community]. | 1975 | 174823 | |
| [different types of oncogenic viruses associated with hemoblastosis in monkeys]. | 1975 | 174875 | |
| viral-induced thymidine kinase isozymes. | 1975 | 174152 | |
| concanavalin a receptors and other cell surface and antigenic characteristics of continuous lymphoblastoid cell lines derived from patients with hodgkin's disease and other malignant lymphomas. | 1975 | 174153 | |
| biological properties of the epstein-barr virus and its possible role in human malignancy. | 1975 | 174156 | |
| consideration of the role of viruses in human cancer. | 1975 | 174158 | |
| [oncogenic viruses and carcinogenesis in man]. | 1975 | 174160 | |
| false positive infectious mononucleosis serology in epilepsy. | positive serum tests for infectious mononucleosis (im) unaccompanied by the clinical syndrome or blood changes characteristic of the disease were detected in 39/177 (22%) mentally subnormal patients investigated with three different commercially available im slide tests. slide positively was still detectable six months later in 27/35 (77%) positive reactors. positive im slide tests were significantly associated with anticonvulsant, primarily phenobarbitone therapy and with concomitant elevations ... | 1975 | 175096 |
| [letters to the editor: bone marrow transplantation and leukemic transformation of transplanted cells]. | 1975 | 175191 | |
| burkitt's lymphoma - a human tumor model system for immunological studies. | burkitt's lymphoma occurs mainly in parts of tropical africa and has attracted the attention of experimental workers due to its epidemiological and clinical features, which indicate a viral etiology and a host immune response to the tumor. as a result of virological studies, epstein-barr virus (ebv) dna has been demonstrated in almost all tested biopsies of african bl. this contrasts to the absence of ebv in all, or almost all, of the non-african burkitt's lymphoma-like tumors, even though the n ... | 1975 | 175835 |
| [epidemiology in the study of the role of viruses in human cancers]. | an epidemiological approach is very useful in the study of the role of viruses in the development of human tumors, if properly integrated with the experimental approach and laboratory studies. certain epidemiological characteristics of human tumours favour a viral etiology, e.g. space and time clustering, vertical and horizontal transmission of a tumour risk, succession in space or in time of viral induced benign lesions and of malignant tumours. in the framework of the association between the e ... | 1975 | 175869 |
| [studies on the relationship between clinical course and antibody titer to epstein-barr virus in nasopharyngeal carcinoma (author's transl)]. | 1975 | 176338 | |
| characterization of epstein-barr virus (ebv) antigens ii. detection of early antigen (s) using anticomplement immunofluorescence (acif) et complement fixation (cf) tests. | using human sera having antibodies against epstein-barr virus (ebv) early antigens (ea) but lacking antibodies directed against the eb nuclear antigen (ebna), the detection of ebv/ea was possible both by the anticomplement immunofluorescent test (acif) and by the classical complement fixation test (cf). the latter is particularly suitable for biochemical studies on ea. | 1975 | 177116 |
| letter: in vitro induction of ebv early antigens in npc epithelial tumour cells by iudr or superinfection. | induction of early antigens in the epithelial tumour cells of npc was achieved both by iudr treatment and ebv superinfection. | 1975 | 177117 |
| clinical applications of cell surface markers. | 1975 | 175398 | |
| [production of interferon or interferon-like susbstances in eb3 cultures after inoculation with human serum containing australia antigen]. | 1975 | 175431 | |
| [new views in medical virology]. | 1975 | 176701 | |
| [infectious mononucleosis. 1. etiology, pathology, pathophysiology and epidemiology]. | 1975 | 176832 | |
| [application of a demographic method for the study of adenoviruses and herpesviruses in a closed infantile community (author's transl)]. | rate of seroconversions to adenoviruses, cytomegaloviruses (cmv) and epstein-barr virus (ebv) was studied from 1965-1973 in 200 infants living in a closed infantile community. the transversal demographic table method was used to evaluate the results of sera examined. seroconversion occurs earlier in the case of adenoviruses with also possess in higher intensity of infection. the intensity of seroconversions to ebv capsid antigen is a little lower, but of all three viruses examined, the spreading ... | 1975 | 176843 |
| establishment and characterization of an epstein-barr virus (ebc)-negative lymphoblastoid b cell line (bja-b) from an exceptional, ebv-genome-negative african burkitt's lymphoma. | an epstein-barr virus (ebv)-negative lymphoblastoid cell line (lcl), bja-b, was established from an african burkitt's lymphoma (bl) which contained no detectable ebv dna and did not express the ebv specified antigen ebna, bja-b cells grow in typically large, flat clumps. all carry surface-bound immunoglobulins, a b lymphocyte marker, and do not form rosettes with sheep erythrocytes. after infection of bja-b cells by ebv the infected cells may produce either ebv-determined nuclear antigen (ebna) ... | 1975 | 179629 |
| appearance of epstein-barr virus-determined nuclear antigen in human epithelial cells following fusion with lymphoid cells. | when human epithelial fl cells were fused with lymphoid cells harboring epstein-barr virus (ebv) genome, ebv-determined nuclear antigen (ebna) immunofluorescence became evident in high frequency in fl nuclei of heterokaryons several days after fusion. the implications of the findings are discussed in relation to the presence of ebv genome in nasopharyngeal carcinoma cells. | 1975 | 179963 |
| an ebv-genome-negative cell line established from an american burkitt lymphoma; receptor characteristics. ebv infectibility and permanent conversion into ebv-positive sublines by in vitro infection. | an in vitro line was derived from an american burkitt lymphoma, designated ra no. 1, which produced malignant tumors when inoculated into thymus-deficient nude mice. the cells have b-lymphocyte characteristics, with surface-associated mu and kappa chains and epstein-barr virus (ebv) receptors, and can be readily infected with ebv in vitro. b95-8 virus induced ebv-determined nuclear antigen (ebna) but not early antigen (ea) in ra no. 1 cells, whereas p3hr-1 virus induced both ebna and ea, but the ... | 1975 | 181343 |
| herpesvirus infections in renal allograft recipients. | 17 of 37 immunosuppressed renal allograft recipients developed clinical and/or serological evidence of herpes simplex virus infections, 7 of 83 developed a zoster rash, 85 of loo had evidence of cytomegalovirus infection and in 3 of 30 an active epstein-barr virus was seen. | 1975 | 181840 |
| epstein-barr virus (ebv)-determined characteristics in lymphoid cells. | 1975 | 183660 | |
| epidemiology of leukemia among baboons of sukhumi monkey colony. | 1975 | 183673 | |
| epidemiology of the epstein-barr virus infection and associated tumors in man. | 1975 | 183674 | |
| multiple cases of lymphoepithelioma and burkitt's lymphoma in a canadian family. | 1975 | 183675 | |
| epstein-barr virus (ebv) specific t and k cell cytotoxicity in vitro. | 1975 | 183683 | |
| cell-mediated immunity in acute infectious mononucleosis. | 1975 | 183684 | |
| replication and latency of epstein-barr virus. | 1975 | 183686 | |
| epstein-barr virus latency and bacteriophage p1 lysogeny-possible analogies. | 1975 | 183687 | |
| indefinite and temporary growths of human cord lymphocytes in vitro by epstein-barr virus. | 1975 | 183688 | |
| human putative oncogenic herpesviruses. | 1975 | 183691 | |
| serum iga antibodies of epstein-barr virus (ebv)-related antigens. a new feature of nasopharyngeal carcinoma. | 1975 | 183692 | |
| comparative studies with different strains of epstein-barr virus in owl monkeys and marmosets. | 1975 | 183693 | |
| transformation of leukocytes from seropositive individuals by epstein-barr virus. | 1975 | 183708 | |
| epstein-barr virus (ebv) expression in transformed human lymphoblastoid cell lines from different sources. | 1975 | 183709 | |
| soluble complement fixing antigens in epstein-barr virus cell systems. | 1975 | 183710 | |
| persistence of herpesvirus nucleic acid in normal and transformed human cells - a review. | 1975 | 190112 | |
| intracellular forms of epstein-barr virus dna in raji cells. | 1975 | 190113 | |
| latent genomes of epstein-barr virus. | of the ebv dnas in raji cells that contained 50 to 60 viral genomes per cell, 90% were separated from high molecular weight cellular dna by centrifugation in a neutral glycerol gradient after lysis of the cells by treatment with pronase and sarkosyl, indicating that the major portion of the ebv dna in raji cells was not integrated linearly into cellular dna. | 1975 | 190114 |
| viral rna in cells carring epstein-barr virus. | 1975 | 190121 | |
| analysis of the dna of epstein-barr viruses and transcriptional products in transformed cells. | 1975 | 190122 | |
| nucleic acid biosynthesis in nuclei of cell infected with herpesviruses (hsv and ebv). | analysis of nuclei isolated from herpes simplex virus (hsv)-infected cells by electrophoresis in polyacrylamide gels showed that only virion-associated dna molecules migrated into the gels. the viral dna molecules, which do not migrate in the gels, are the precursors for the mature viral dna. centrifugation of deoxycholate-treated infected nuclei in sucrose gradients revealed that most of the viral dna co-sedimented with the cellular dna. the dna-dependent rna polymerase activity also co-sedimen ... | 1975 | 190126 |
| dna synthesis in nuclei isolated from cultured lymphoblastoid cells. | 1975 | 190127 | |
| studies on the isolation of cell-associated epstein-barr virus antigens by affinity chromatography. | 1975 | 190129 | |
| virus-induced antigens - a review. | 1975 | 190131 | |
| the epstein-barr virus (ebv): evidence for ebv strains. | 1975 | 190135 |