Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [sequence polymorphism of major house dust mite allergens]. | to determine the sequence variation of the groups 1 and 2 allergens from dermatophagoides pteronyssinus and dermatophagoides farinae in different geographical regions. | 2008 | 18637583 |
| house dust mites on skin, clothes, and bedding of atopic dermatitis patients. | atopic dermatitis is a common allergic condition in children, often associated with a positive skin reaction to house dust mite allergens. | 2008 | 18717857 |
| oral administration of allergen extracts from dermatophagoides farinae desensitizes specific allergen-induced inflammation and airway hyperresponsiveness in rats. | clinically sublingual immunotherapy (slit) by using allergen extracts effectively alleviates the symptoms of allergic rhinitis and asthma. supposed that oral administration of high-dose of allergen extracts imitates slit and may prevent ige-related responses in allergic diseases, we investigated the effects of oral administration of allergen extracts from dermatophagoides farinae (derf) on allergen-induced inflammation and airway hyperresponsiveness (ahr) in a model of asthmatic rat. after admin ... | 2008 | 18721904 |
| bcg-induced dendritic cell responses and suppression of interleukin-5 production from t cells in atopic asthmatics. | bacille calmette-guérin (bcg) induces potent th1 responses with the help of interleukin (il)-10 and il-12 released from dendritic cells (dcs), and suppresses th2- associated allergic reactions. however, there are still some controversies on therapeutic effects of bcg in asthmatics. this study investigated whether bcg administration to dcs suppresses il-5 production from t cells in atopic asthmatics. dcs derived from peripheral blood of subjects were cultured with or without bcg and dermatophagoi ... | 2008 | 18756049 |
| the prevalence of positive intradermal allergy tests in 114 dogs with atopic dermatitis in the bangkok metropolis, thailand. | intradermal allergy tests using 47 selected local aero-allergens were performed on 114 dogs with atopic dermatitis. the subject animals visited the dermatology unit at the veterinary teaching hospital of kasetsart university or the slv pet hospital with chronic pruritus and various skin lesions. allergen extracts were composed of: 4 house dust and house dust mites, 7 household insects, 24 pollens, 11 mold spores, and kapok. the prevalence of sensitization to various allergens were as follows: de ... | 2008 | 18783836 |
| inhibition of skin inflammation and atopic dermatitis by topical application of a novel ceramide derivative, k112pc-5, in mice. | pc-9s (n-ethanol-2-mirystyl-3-oxo-stearamide) is a synthetic ceramide and has been known to be effective in atopic and psoriatic patients. k112pc-5 (2-acetyl-n-(1,3-dihydroxyisopropyl)-tetradecanamide) is a novel ceramide derivative of pc-9s. in the present study, we examined the effect of k112pc-5 on macrophage and t lymphocyte function in primary macrophages and splenocytes, respectively, as well as the effect of topical application of k112pc-5 on skin inflammation and atopic dermatitis (ad) i ... | 2008 | 18787789 |
| determination of threshold concentrations of multiple allergenic extracts for equine intradermal testing using normal horses in three seasons. | forty-one normal horses were evaluated for reactivity to intradermally injected aqueous allergens to determine allergen threshold concentrations (tc), with potential relevance to equine intradermal testing (idt). horses were tested three times over 1 year to assess seasonal variation in reactivity, using three to five serial dilutions of 27 allergens each time. injection sites were evaluated after 15 min, 1 h, 4 h and 24 h. the highest allergen concentration at which < 10% of horses demonstrated ... | 2008 | 18803619 |
| frequency of acute systemic reactions in patients with allergic rhinitis and asthma treated with sublingual immunotherapy. | several studies have demonstrated the efficacy and safety of sublingual immunotherapy in the treatment of respiratory allergy. | 2008 | 18814454 |
| clinical analyses of atopic dermatitis in the aged. | the aim of the present study was to analyze the characteristics of atopic dermatitis (ad) in the senile phase. subjects were comprised of 16 patients investigated for clinical features, serum immunoglobulin (ig)e levels and skin manifestations. mean age was 76.9 +/- 6.2 years (range, 68-87), with a man : woman ratio of 3:1. mean age at onset was 67.7 +/- 15.7 years. eight patients (50%) had personal histories of chronic eczema until the young adult phase and three patients (18.8%) showed the cla ... | 2008 | 18837700 |
| dermatophagoides farinae-specific igg responses in atopic dogs undergoing allergen-specific immunotherapy with aqueous vaccines. | the molecular and immunologic mechanisms associated with successful allergen-specific immunotherapy (asit) have not been completely elucidated. the aim of this study was to characterize the changes in dermatophagoides farinae-specific igg in atopic dogs undergoing asit using aqueous vaccines. fifteen atopic dogs with a positive skin test reaction to d. farinae were treated with aqueous vaccines for a minimum of 2 months following a standard protocol. serum samples were collected before and durin ... | 2008 | 19086120 |
| [aeroallergen spectrum of 387 patients with allergic rhinitis in changsha area]. | to investigate aeroallergen spectrum of patients with allergic rhinitis in changsha area and analyze its related factors. | 2008 | 19086661 |
| effect of bakumijiogan, an herbal formula in traditional chinese medicine, on atopic dermatitis-like skin lesions induced by mite antigen in nc/jic mice. | we evaluated the effectiveness of bakumijiogan (bjg), an herbal formula in traditional chinese medicine used to treat atopic dermatitis (ad), using a nc/jic mouse model of ad. ad symptoms were induced by repeated injections of dermatophagoides farinae antigen (df-antigen) into the ear auricle at 2- to 3-d intervals for 16 d. ear thickness dramatically increased up to 16 d after the first injection of df-antigen. daily oral administration of bjg from 7 d before to 16 d after the first injection s ... | 2008 | 18981582 |
| serum allergen specific immunoglobulin e levels in patients with allergic conjunctivitis. | to evaluate serum allergen specific immunoglobulin e (ige) levels in patients with various types of allergic conjunctivitis. | 2008 | 18850541 |
| [age features of the allergens in allergic rhinitis patients of different age in hubei area]. | to investigate the distribution of positive allergens in patients with allergic rhinitis and the discrepancy among different age group. | 2008 | 18950005 |
| importance of house dust and storage mites in canine atopic dermatitis in the geographic region of galicia, spain. | sensitisation to mites is frequent in atopic dogs. the main mite genus involved in canine atopic dermatitis is dermatophagoides. the importance of storage mite allergens in dogs has been controversial. the aim of this study was to evaluate the sensitisation rates against storage mites (lepidoglyphus destructor and tyrophagus putrescentiae) and house dust mites (dermatophagoides farinae and d. pteronyssinus) in atopic dogs from galicia, a highly humid and temperate region of spain, using a fcepsi ... | 2008 | 18669243 |
| contact and aeroallergens in adulthood atopic dermatitis. | atopic dermatitis (ad) is a clinically well-defined, chronic-intermittant, genetically predisposed skin disease. the increasing number of adult cases observed in the last years has turned the attention to ascertaining factors eliciting skin symptoms. studies have revealed numerous environmental components (e.g. contact and aeroallergens) that may play an important role in sustaining the symptoms. the aim of the study was to search for contact allergens and aeroallergens triggering the skin disea ... | 2008 | 18680530 |
| carry-over effect on ifn-gamma production induced by allergen-specific immunotherapy. | allergic rhinitis is characterized by th2 polarization and defective ifn-gamma production. specific immunotherapy determines an allergen-specific clinical improvement. | 2008 | 18691675 |
| comparative mites and cockroaches sensitization study in three cities of mexico. | in mexico there are few research papers dealing with mites and cockroaches sensibilizing in patients suffering from respiratory allergies and even less susceptibility comparative studies to the same between cities having different climatic and geographic characteristics. | 2008 | 19157220 |
| [preliminary investigation on phylogenetic relationship among three common species of house dust mites]. | dermatophagoides farinae, d. pteronyssinus and euroglyphus maynei were used for the investigation. the cdna fragment coding for der f1 and der f2 were amplified by pcr, cloned and sequenced. by bioinformatics softwares, the amino acid sequences for der f1 and der f2 were deduced and compared with those for the groups 1 and 2 allergens of d. pteronyssinus and e. maynei available in genbank. amino acid sequence similarity analysis showed that der p1 shared 84% identical residues with eur m1 and 83 ... | 2008 | 19157310 |
| morphology and three-dimensional reconstruction of the digestive system of dermatophagoides farinae. | the digestive system of dermatophagoides farinae remains poorly documented. | 2008 | 18268390 |
| acaricidal activity and function of mite indicator using plumbagin and its derivatives isolated from diospyros kaki thunb. roots (ebenaceae). | acaricidal effects of materials derived from diospyros kaki roots against dermatophagoides farinae and d. pteronyssinus were assessed using impregnated fabric disk bioassay and compared with that of the commercial benzyl benzoate. the observed responses varied according to dosage and mite species. the ld50 values of the chloroform extract of diospyros kaki roots were 1.66 and 0.96 microg/cm2 against d. farinae and d. pteronyssinus. the chloroform extract of diospyros kaki roots was approximately ... | 2008 | 18309277 |
| assessment of cross-reactivity among five species of house dust and storage mites. | in vitro cross-reactivity among two house dust (dermatophagoides farinae, d. pteronyssinus) and three storage (acarus siro, tyrophagus putrescentiae, lepidoglyphus destructor) mites was examined in 20 mite-sensitive dogs with natural occurring atopic dermatitis (group a), 13 high-ige beagles experimentally sensitized to d. farinae (group b), and five healthy beagles (group c). intradermal testing (idt) and serology for allergen-specific ige demonstrated that co-sensitization for all possible pai ... | 2008 | 18336423 |
| comparison between an intradermal skin test and allergen-specific ige-elisa for canine atopic dermatitis. | the aim of this study was to compare the results of an intradermal skin test (idst) with those of an allergen-specific ige-elisa in 210 dogs with atopic dermatitis. all the dogs had a clinical diagnosis of atopic dermatitis and underwent an idst. the sera of all dogs were analysed for allergen-specific ige by elisa using the monoclonal antibody d9 against dog ige. idst was used as the standard assay. in both methods, the following antigens provided a positive test result: dermatophagoides farina ... | 2008 | 18429502 |
| korean ginseng-induced occupational asthma and determination of ige binding components. | a number of case reports on occupational asthma caused by herbal medicines have been issued, for example, on sanyak, chunkung, banha, and brazilian ginseng. recently, cases of occupational asthma induced by sanyak and korean ginseng have been reported, but the pathogenic mechanisms involved are unknown. this study was carried out to evaluate the immunologic mechanism underlying korean ginseng-induced occupational asthma. a patient engaged in korean ginseng wholesale was referred for recurrent dy ... | 2008 | 18437005 |
| immunomodulatory effects of cpg oligodeoxynucleotides on house dust mite-induced airway inflammation in mice. | cpg oligodeoxynucleotides (cpg odns) are reported to protect against airway eosinophilia and hyperresponsiveness in animal models of asthma. however, little is known about the effects of cpg odns on house dust mites, one of the most common environmental allergens, causing allergic asthma. in the present study, we evaluated the immunomodulatory effects of cpg odns on the development of house dust mite-induced airway inflammation and remodeling in mice. | 2008 | 18446048 |
| cloning, sequence analysis, and expression of cdna coding for the major house dust mite allergen, der f 1, in escherichia coli. | our objective was to clone, express and characterize adult dermatophagoides farinae group 1 (der f 1) allergens to further produce recombinant allergens for future clinical applications in order to eliminate side reactions from crude extracts of mites. based on genbank data, we designed primers and amplified the cdna fragment coding for der f 1 by nested-pcr. after purification and recovery, the cdna fragment was cloned into the pmd19-t vector. the fragment was then sequenced, subcloned into the ... | 2008 | 18545812 |
| [urticaria in relation to mite sensitivity and immunotherapy with injection dermatophagoidei farinae]. | to investigate the prevalence of mite sensitivity in patients with urticaria or other skin rashes, and to observe the clinical efficacy of a specific immunotherapy (sit) by the injection dermatophagoides farinae for the patients. | 2008 | 19288915 |
| acaricidal constituents isolated from sinapis alba l. seeds and structure-activity relationships. | allyl isothiocyanate (aitc) and phenethyl isothiocyanate (peitc) were isolated from sinapis alba l. seeds and their effects against dermatophagoides farinae and d. pteronyssinus were evaluated using the impregnated fabric disk method. the ld 50 values of their compounds and derivatives were then compared with those of a commercial acaricide, benzyl benzoate. on the basis of the ld 50 values against d. farinae, peitc (0.21 microg/cm(2)) was the most toxic, followed by benzyl isothiocyanate (0.55 ... | 2008 | 18844359 |
| mite-control activities of active constituents isolated from pelargonium graveolens against house dust mites. | the mite-control activities of materials obtained from pelargonium graveolens oil against dermatophagoides farinae and d. pteronyssinus were examined using an impregnated fabric disk bioassay and were compared with those shown by commercial benzyl benzoate and n,n-diethylm- toluamide (deet). purification of the biologically active constituents from p. graveolens oil was done by silica gel chromatography and high performance liquid chromatography. the structures of the active components were anal ... | 2008 | 18955817 |
| anaphylaxis following the ingestion of flour contaminated by house dust mites--a report of two cases from singapore. | this study presents two patients who developed anaphylaxis after eating mite-contaminated food, and also contains a survey of dust-mites contamination in flour samples from singapore households. the clinical records of each patient was studied. patient a developed anaphylaxis twenty minutes following the ingestion of home-made fried fish coated with japanese flour, while patient b developed similar life-threatening symptoms one hour after the ingestion of home baked scones. both patients were ns ... | 2008 | 19054935 |
| long-term immunotherapy for perennial allergic rhinitis: relationship of specific igg levels to skin-prick test results and clinical symptoms and signs. | we studied 63 adults with perennial allergic rhinitis and positive skin-prick tests for dermatophagoides pteronyssinus (dp) and dermatophagoides farinae (df) who had not previously received any type of immunotherapy or pharmacotherapy for their condition. we injected these patients with a 50% dp/50% df modified allergen intradermally in accordance with the classic immunotherapy scheme once a week for 30 months. specific immunotherapy (sit) was administered until the specific igg (sigg) concentra ... | 2008 | 19105132 |
| the pattern of sensitisation to inhalant allergens in omani patients with asthma, allergic rhinitis and rhinoconjunctivitis. | identification of relevant allergens that are prevalent in each environment which may have diagnostic and therapeutic implications in allergic diseases. this study aimed to identify the pattern of sensitisation to inhalant allergens in omani patients with asthma, allergic rhinitis and rhinoconjunctivitis. | 2008 | 21748078 |
| chitosan microparticles loaded with mite group 2 allergen der f 2 alleviate asthma in mice. | in recent years, nanoparticle materials have found wide applications in drug transport and release systems. chitosan is a good carrier for proteins, peptides, and nucleic acids because of its favorable release properties and ability to increase membrane permeability. | 2008 | 19123437 |
| an analysis of skin prick test reactions in allergic rhinitis patients in istanbul, turkey. | this retrospective, population-based study reviewed skin prick test (spt) results against various allergens of 1,552 patients with allergic rhinitis (ar) in the district of kartal, istanbul, turkey. the skin prick tests yielded a positive result in 946 patients (60.9%). seven hundred and forty-give (48%) patients had perennial ar, 558 (36%) perennial ar with seasonal exacerbations and 249 (16%) had seasonal ar. the prevalence of ar was highest in the age of 21-40 years with 48.7%. the allergen g ... | 2009 | 19548626 |
| the importance of starch and sucrose digestion in nutritive biology of synanthropic acaridid mites: alpha-amylases and alpha-glucosidases are suitable targets for inhibitor-based strategies of mite control. | the adaptation of nine species of mites that infest stored products for starch utilization was tested by (1) enzymatic analysis using feces and whole mite extracts, (2) biotests, and (3) inhibition experiments. acarus siro, aleuroglyphus ovatus, and tyroborus lini were associated with the starch-type substrates and maltose, with higher enzymatic activities observed in whole mite extracts. lepidoglyphus destructor was associated with the same substrates but had higher activities in feces. dermato ... | 2009 | 19480003 |
| acaricidal activities of major constituents of essential oil of juniperus chinensis leaves against house dust and stored food mites. | the acaricidal activities of major constituents from the oil of juniperus chinensis (var. globosa) leaves were compared with those of deet (n,n-diethyl-m-toluamide) by using impregnated fabric disk bioassay against dermatophagoides spp. and tyrophagus putrescentiae. toxicity varied with doses as well as chemical composition. the 50% lethal doses (ld50) of j. chinensis oil against dermatophagoides farinae, dermatophagoides pteronyssinus, and t. putrescentiae were 21.60, 19.89, and 38.10 microg/cm ... | 2009 | 19722401 |
| sensitization of children to storage mites in kutahya, turkey. | specific ige against acarus siro, glycphagus domesticus, tyrophagus putrescentiae, and lepidoglyphus destructor have been investigated by elisa in sera of 92 children. of them, 41 were found to be specific ige positive (> or = 0.35 iu/ml) against at least one of house dust mite species, dermatophagoides pteronyssinus and dermatophagoides farinae, by an immunoblot. in 65.9% of the dust mite-sensitized children, specific ige against at least one of these mite species was found. sensitization level ... | 2009 | 19967087 |
| seasonal dynamics and distribution of house dust mites in china. | house dust mites are widely distributed in the human habitat and work environment and produce very powerful allergens. the most important allergy-causing mites found in homes worldwide are the house dust mites dermatophagoides farinae and d. pteronyssinus and the storage mite blomia tropicalis. it is important to know which mite species are present in a geographical area when performing diagnostic testing and prescribing immunotherapy. we classified the breeding situations of house dust mites in ... | 2009 | 20103849 |
| influence of environmental characteristics and climatic factors on mites in the dust of air-conditioner filters. | to investigate mites in the dust of air-conditioner filters (macf) in china, a total of 652 dust samples were collected from six cities: guangzhou (n = 129), nanchang (n = 127), shanghai (n = 113), xian (n = 93), beijing (n = 93), and shenyang (n = 79). tarsonemus granarius was the most dominant species (87.2%). dermatophagoides pteronyssinus and dermatophagoides farinae only represented 7.0 and 3.0% of total mites, respectively. with latitude increasing, both mite occurrence rate (p < 0.001) an ... | 2009 | 19840146 |
| selective allergy to lobster in a case of primary sensitization to house dust mites. | allergy to only 1 kind of seafood is uncommon. we report a case of selective allergy to lobster. we studied a 30-year-old man who suffered generalized urticaria, facial erythema, and pharyngeal pruritus after eating lobster. he had a more than 10-year history of mild persistent asthma and sensitization to house dust mites. the study was performed by skin prick test, and prick-prick test, oral food challenge, specific immunoglobulin (ig) e determinations by cap (phadia, uppsala, sweden) and advia ... | 2009 | 19862942 |
| house dust mite major allergen der f 1 enhances proinflammatory cytokine and chemokine gene expression in a cell line of canine epidermal keratinocytes. | house dust mite (hdm) allergens are the most common allergens involved in the induction of ige-mediated hypersensitivity. recently, epicutaneous sensitization with hdm allergens has been emphasized in the development of atopic dermatitis (ad); however, direct stimulation of canine keratinocytes by mite allergens has not been well investigated. in the present study, we investigated the effects of der f 1, a major allergen of dermatophagoides farinae, on cytokine and chemokine gene expression in a ... | 2009 | 19446888 |
| dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells. | house dust mites are a significant source of airborne allergen worldwide, but there is little understanding of how they so potently generate allergic inflammation. we found that extracts from the house dust mites dermatophagoides farinae (df) and dermatophagoides pteronyssinus and from the mold aspergillus fumigatus stimulated a rapid and robust production of cysteinyl leukotrienes (cys-lts), proinflammatory lipid mediators, from mouse bone marrow-derived dendritic cells (bmdcs). con a affinity ... | 2009 | 19124755 |
| [acaricidal activity of clove bud oil against dermatophagoides farinae (acari: pyroglyphidae)]. | volatile oil from the clove bud was extracted by petroleum ether using soxhlet extractor. the acaricidal activity was examined using direct contact and vapour phase toxicity bioassays. in a filter paper contact toxicity bio-assay, at 2.5 h after treatment, clove bud oil at a dose of 12.20 microg/cm2 killed all dust mites. as judged by 24-h ld50 values, potent fumigant action was observed with clove bud oil (12.20 microg/cm2), showing an adequate acaricidal activity against indoor dermatophagoide ... | 2009 | 20232631 |
| ebastine increases ifn-gamma production in patients with persistent allergic rhinitis. | nasal obstruction is a leading symptom in patients with allergic rhinitis and depends on inflammation characterized by th2 polarization. thus, ifn-gamma is typically deficient in allergic patients. it has been previously reported that ebastine is able to reduce th2-dependent cytokines. the aim of this study is to preliminarily evaluate ifn-gamma production by peripheral blood mononuclear cells (pbmnc) and clinical changes after a treatment with lyophilized ebastine in patients with persistent al ... | 2009 | 19321044 |
| allergic rhinitis and co-morbid asthma: perspective from india -- aria asia-pacific workshop report. | in india, allergic rhinitis (ar) is considered to be a trivial disease, despite the fact that symptoms of rhinitis were present in 75% of children and 80% of asthmatic adults. traditionally, ar was also divided into seasonal or perennial, based on the time of occurrence of symptoms during the year. the aria workshop report proposed that patients be categorized as "intermittent" and "persistent" while severity was classified as "mild" and "moderate-severe". patients with ar, depending on their pr ... | 2009 | 19548632 |
| different phenotypes of intermittent and persistent respiratory allergy in zagreb, croatia. | allergic rhinitis (ar) is a major chronic respiratory disease because of its prevalence, its impacts on the quality of life, economic burden and links with asthma. a significant relationship between the severity of rhinitis and prevalence of asthma in allergic patients was found both in patients suffering from seasonal rhinitis and in those suffering from perennial-allergic rhinitis (par) and asthma. the aim of the study was to investigate allergy phenotypes in patients with intermittent allergi ... | 2009 | 19572486 |
| interference of dermatophagoides' specific immunoglobulins g in the quantification of mite's specific immunoglobulins e. | in order to investigate the interference of specific igg in the quantification of specific ige, using the immunocap 250 system, we studied, in parallel, the interference by total adsorption of interferent and the classical method of adding interferent increasingly. furthermore, to evaluate if the interference is affected by different solid phases, total extract of dermatophagoides pteronyssinus and recombinant allergens of dermatophagoides farinae were used. the results showed a statistical sign ... | 2009 | 19591046 |
| relationship between pretreatment specific ige and the response to omalizumab therapy. | omalizumab, an anti-ige antibody, has proven efficacy in patients with moderate-to-severe and severe persistent allergic (ige-mediated) asthma. while previous analyses have had some limited success in predicting which patients will gain greatest benefit based on pretreatment baseline characteristics, it remains important to try to improve this predictability. | 2009 | 19627273 |
| dermatophagoides farinae mite allergen and specific immunotherapy in shanghai. | studies on mite allergy had been launched by the shanghai first medical college since 1970's in this country. the preparations of smu-df from the local specimens of dermatophagoides farinae (df) in shanghai have been shown the highest allergenic potency in comparison with that of the foreign ones, including the df preparations from usfda, vus and alk. similar patterns of the protein curves were yielded by gel filtration, indicating almost similar allergenicities with both df pure mite body and i ... | 2009 | 20066974 |
| an association between floor vacuuming and dust-mite and serum eosinophil cationic protein in young asthmatics. | although vacuum cleaning is recommended to reduce allergen levels and improve asthma and allergic rhinitis symptoms, some studies suggest it may increase allergen load in homes. we conducted a cross-sectional study to determine if home floor vacuuming was associated with sensitization to dust-mites and cockroaches, and serum eosinophil cationic protein (ecp), a biomarker for atopy, in 102 physician-diagnosed spirometry-confirmed asthmatics. we collected data on floor type, floor cleaning method ... | 2009 | 19682104 |
| levels of house dust mite-specific serum immunoglobulin e (ige) in different cat populations using a monoclonal based anti-ige enzyme-linked immunosorbent assay. | levels of serum immunoglobulin e (ige) specific for the house dust mites (hdms) dermatophagoides farinae (df) and dermatophagoides pteronyssinus (dp) in 58 cats with clinical signs suggestive of atopic dermatitis (allergic dermatitis cats), 52 cats with no history of allergic or immunological disease (nonallergic cats) and 26 specific pathogen-free (spf) cats were measured using a monoclonal anti-ige enzyme-linked immunosorbent assay. reactivity to both native and reduced hdm allergens was compa ... | 2009 | 20178495 |
| improved trna prediction in the american house dust mite reveals widespread occurrence of extremely short minimal trnas in acariform mites. | atypical trnas are functional minimal trnas, lacking either the d- or t-arm. they are significantly shorter than typical cloverleaf trnas. widespread occurrence of atypical trnas was first demonstrated for secernentean nematodes and later in various arachnids. evidence started to accumulate that trnas of certain acariform mites are even shorter than the minimal trnas of nematodes, raising the possibility that trnas lacking both d- and t-arms might exist in these organisms. the presence of clover ... | 2009 | 20003349 |
| cloning, sequence analysis and expression in e. coli of the group 3 allergen of dermatophagoides farinae. | the dust mites, which are mostly represented by dermatophagoides spp. (acari: pyroglyphidae), are the major sources of indoor allergens. identification and characterization of these mite allergen molecules are an important step in the development of new effective diagnostic procedures and possible therapeutic strategies for allergic disorders associated with dust mites. | 2009 | 19951588 |
| skin sensitization and classroom exposure to dermatophagoides pteronyssinus and dermatophagoides farinae allergens in andean ecuadorian students. | 2009 | 19880444 | |
| [otorhinolaryngology]. | house dust, as well as cedar pollen, is an important antigen that causes nasal allergy. various materials and species of mites are included in house dust; in particular, dermatophagoides pteronyssinus and dermatophagoides farinae are important causative antigens of asthma and nasal allergy. these mites proliferate in house dust when certain conditions such as temperature and humidity are satisfied and cause allergies in people. for the treatment of allergic rhinitis caused by house dust, it is i ... | 2009 | 19899535 |
| early compliance and efficacy of sublingual immunotherapy in patients with allergic rhinitis for house dust mites. | sublingual immunotherapy (slit) has recently received much attention around the world as a treatment for allergic rhinitis. this study aimed to investigate the efficacy and adverse effects of slit in korean patients with allergic rhinitis caused by house dust mites. the treatment compliance and the patient satisfaction with slit were also assessed. | 2009 | 19784406 |
| indoor mites and forensic acarology. | house dust mites (hdm) have been shown to produce allergens causing atopic allergies in human beings, known in medicine as house-dust-mite allergy or atopy. over the past 25 years (1981-2006) a survey of dust samples from different places was made in the southern part of poland, to determine the diversity of indoor acarofauna. in total, 1,532 samples were taken from dwellings, hospitals, libraries, research laboratories, drug-stores, and offices and other workplaces. more than 30 mite species we ... | 2009 | 19636803 |
| sex-specific differences in allergic sensitization to house dust mites: a meta-analysis. | the prevalence of allergic airway diseases in childhood is higher in boys than in girls but switches toward a female predominance in adolescents and adults. the sex-specific prevalence of allergic sensitization to 1 of the most common allergens worldwide, house dust mite (hdm), has not been examined systematically by age group and species. | 2009 | 19558007 |
| comparison and evaluation of several dermatophagoides pteronyssinus allergen extracts for skin prick test. | to evaluate the significance of several dermatophagoides pteronyssinus allergen extracts for skin prick test (spt) in patients allergic to dermatophagoides pteronyssinus. | 2009 | 19618604 |
| [prevalence of house dust mite allergy in cases with atopic disease symptoms in kocaeli province, turkey]. | the aim of this study was to investigate the prevalence of house dust mite sensitization and to detect the ige and eosinophilic cationic protein (ecp) levels in the positive cases living in kocaeli province (located in northwest region of turkey). the results of mixed house dust mite skin tests of 1279 patients (620 male, 659 female) of which 670 were children (3-14 years), 68 were adolescents (15-19 years) and 541 were adults (20-86 years) who were admitted to kocaeli university medical faculty ... | 2009 | 19621618 |
| dermatophagoides farinae extract induces severe atopic dermatitis in nc/nga mice, which is effectively suppressed by the administration of tacrolimus ointment. | atopic dermatitis (ad) is a chronic inflammatory skin disease, which is accompanied by marked increases in the levels of inflammatory cells, including mast cells and eosinophils as well as t cells and macrophages. to investigate the expression pattern of chemokines in ad, a house dust mite, dermatophagoides farinae extracts (dfe)-induced nc/nga ad model was developed in mice, and this model was used to determine the expression levels of chemokines in atopic lesions using dna microarrays and rt-p ... | 2009 | 19162238 |
| a multicentre study assessing the prevalence of sensitizations in patients with asthma and/or rhinitis in china. | the prevalence of sensitization in patients with asthma and rhinitis in mainland china remains unclear. | 2009 | 19210346 |
| mite sensitization among latina women in new york, where dust-mite allergen levels are typically low. | in new york (ny), latinos often have greater asthma morbidity than other ethnicities, and dust-mite sensitization is common despite low allergen levels. we investigated mite allergen exposure and sensitization in atopic and/or asthmatic women, the majority being puerto rican. women (n = 274) recruited for a birth cohort study were visited postnatally. dust from their homes was analyzed for mite allergens (der f 1, der p 1, and blo t 5). serum was analyzed for total and allergen-specific ige. thi ... | 2009 | 19220508 |
| augmentation of regulatory t cells in allergic individuals by recombinant der f 2 peptide with fungal immunomodulatory peptide fve. | the suppressive function of regulatory t (treg) cells is compromised in allergic individuals, and the augmentation of treg cells has been demonstrated after successful allergen immunotherapy. | 2009 | 19354068 |
| influence of epinastine hydrochloride, an h1-receptor antagonist, on the function of mite allergen-pulsed murine bone marrow-derived dendritic cells in vitro and in vivo. | there is established concept that dendritic cells (dcs) play essential roles in the development of allergic immune responses. however, the influence of h(1) receptor antagonists on dc functions is not well defined. the aim of the present study was to examine the effect of epinastine hydrochloride (ep), the most notable histamine h(1) receptor antagonists in japan, on dermatophagoides farinae (der f)-pulsed mouse bone marrow-derived dcs in vitro and in vivo. ep at more than 25 ng/ml could signifi ... | 2009 | 19381339 |
| bacillus thuringiensis var. tenebrionis control of synanthropic mites (acari: acaridida) under laboratory conditions. | bacillus thuringiensis (bt) toxins present a potential for control of pest mites. information concerning the effect of bt and its possible application to the biocontrol of synathropic mites is rare. the toxic effect of bacillus thuringiensis var. tenebrionis producing cry3a toxin was tested on the mites acarus siro l., tyrophagus putrescentiae (schrank), dermatophagoides farinae hughes, and lepidoglyphus destructor (schrank) via feeding tests. fifty mites were reared on bt additive diets in conc ... | 2009 | 19381844 |
| prevalence of immunoglobulin e-mediated food allergy in 6-9-year-old urban schoolchildren in the eastern black sea region of turkey. | the prevalence of adverse reactions to food in childhood in turkey is not known. | 2009 | 19400894 |
| specific allergic sensitization in parents and their 18-year-old offspring in the suburban detroit childhood allergy study. | allergic sensitization is increased among offspring of sensitized parents. | 2009 | 19409605 |
| [house dust mite allergy: myths and realities]. | since 1967, house dust mites have been shown to be the main allergens to be blamed in household dust allergy. in our countries, dermatophagoides pteronyssinus and dermatophagoides farinae are predominant. we find them by millions in our bedding. they are responsible of allergic reactions like asthma, rhinitis and atopic dermatitis. different treatments are available of which some have proved there effectiveness, like subcutaneous immunotherapy and standard symptomatic treatments. on the other ha ... | 2009 | 19441749 |
| [mites in mattress dust and relevant environmental factors in student dormitories in shenzhen]. | three hundred and eight mattress dust samples were collected from college dormitories in shenzhen with a mite prevalence of 88% (271/308). from the samples, 6163 mites were isolated and identified. dermatophagoides farinae, d. pteronyssinus and blomia tropicalis were three most abundant species, occupying 29.7%, 21.7% and 17.9%, respectively. it was found that sex of the students, mattress cover (bamboo mat or bed sheet), with or without air conditioner installation, and daily using of air condi ... | 2009 | 19459513 |
| allergenic profile of nasal polyposis. | nasal polyposis is highly prevalent in the general population. its exact origin is unknown, although several factors are involved in the etiology and development of this condition. clinical patterns, a history of atopy, environmental exposure, eosinophil-mediated inflammation, the presence of inflammatory mediators, and sensitization to some allergens indicate that nasal polyposis is associated with allergic phenomena. the aim of this study was to identify the association between nasal polyposis ... | 2009 | 19476014 |
| crystal structures of mite allergens der f 1 and der p 1 reveal differences in surface-exposed residues that may influence antibody binding. | the group 1 mite allergens der f 1 and der p 1 are potent allergens excreted by dermatophagoides farinae and dermatophagoides pteronyssinus, respectively. the human immunoglobulin e antibody responses to the group 1 allergens show more cross-reactivity than the murine immunoglobulin g antibody responses, which are largely species specific. here, we report the crystal structure of the mature form of der f 1, which was isolated from its natural source, and a new high-resolution structure of mature ... | 2009 | 19136006 |
| effect of environmental allergen sensitization on asthma morbidity in inner-city asthmatic children. | asthma causes significant morbidity in children, and studies have demonstrated that environmental allergies contribute to increased asthma morbidity. | 2009 | 19489919 |
| local nasal immunotherapy: efficacy of dermatophagoides farinae-chitosan vaccine in murine asthma. | local nasal immunotherapy has been reported to be effective for airway allergic diseases. a biodegradable material, chitosan (cs), has been reported to be safe and effective in allergen delivery. in this study, we tested immunotherapeutic efficiency by intranasal administration of der f entrapped in cs microparticles to sensitized mice. | 2009 | 19494519 |
| house dust mite extracts activate cultured human dermal endothelial cells to express adhesion molecules and secrete cytokines. | the human skin contacts molecules from house dust mites that are ubiquitous in many environments. these mite-derived molecules may penetrate the skin epidermis and dermis and contact microvascular endothelial cells and influence their function. the purpose of this study was to determine the response of normal human dermal microvascular endothelial cells to extracts of the dust mites, dermatophagoides farinae, d. pteronyssinus, and euroglyphus maynei with and without endotoxin (lipopolysaccharide ... | 2009 | 19496432 |
| evaluation of lactobacillus rhamnosus strain gg for the prevention of atopic dermatitis in dogs. | to evaluate the efficacy of the probiotic lactobacillus rhamnosus strain gg for the alleviation or prevention of clinical signs of atopic dermatitis (ad) in genetically predisposed dogs. | 2009 | 19496662 |
| the effect of rush immunotherapy with house dust mite in the production of il-5 and ifn-gamma from the peripheral blood t cells of asthmatic children. | although the mechanisms are unclear, rush immunotherapy (rit) may be effective to treat allergic diseases. we investigated the long-term modifications of cellular immunity as a mechanism of rit. the rit group, included 15 house dust mite (hdm)-sensitized asthmatic children, received rit only with dermatophagoides farinae (der f) and dermatophagoides pteronyssinus (der p), whereas the control group, consisted of 10 hdm-sensitized asthmatic children, did not receive rit. the asthma symptom scores ... | 2009 | 19543499 |
| familial aggregation of skin sensitization to aeroallergens in a rural area in china. | the prevalence of allergic sensitization has increased all over the world during last years and allergic sensitization may be related to genetic or environmental factors or to both. the objective of this study was to estimate the prevalence rates of allergic sensitization and assess the familial aggregation of allergic sensitization to aeroallergens in asthma index families. | 2009 | 18716407 |
| contribution of itch-associated scratch behavior to the development of skin lesions in dermatophagoides farinae-induced dermatitis model in nc/nga mice. | recently, we have reported that the pathophysiological features of dermatitis induced by the repeated application with dermatophagoides farinae (df) extract ointment in nc/nga mice were similar to those observed in the patients with atopic dermatitis. in the present study, we first examined whether the application of df in other mouse strains could induce dermatitis. the repeated application of df body (dfb) ointment to the barrier-disrupted back of icr, c57bl/6, and balb/c mice did not cause an ... | 2009 | 18979107 |
| genetic impact of a butyrophilin-like 2 (btnl2) gene variation on specific ige responsiveness to dermatophagoides farinae (der f) in japanese. | dermatophagoides farinae (der f) is one of the most frequently implicated allergens in several allergic diseases. several genome-wide screens have identified a linkage between chromosome 6p21 and mite-specific ige responsiveness. butyrophilin-like 2 (btnl2) is a member of the immunoglobulin superfamily and, on the basis of its homology to b7-1, has been implicated as a costimulatory molecule involved in t-cell activation. btnl2 resides in the hla region on chromosome 6p21, and significant associ ... | 2009 | 19050377 |
| acaricidal activity of triketone analogues derived from leptospermum scoparium oil against house-dust and stored-food mites. | various attempts to control the populations of house-dust and stored-food mites have been implemented using synthetic chemicals. although effective, the repeated use of these chemicals has led to resistance owing to the mite's high reproductive potential and short life cycle. therefore, this study aimed to develop natural acaricides using oils derived from leptospermum scoparium jr & g forst., which may affect the overall biological activity of a mite without adverse effects. results were compar ... | 2009 | 19051215 |
| allergen-specific ige measurement with the immulite 2000 system: intermethod comparison of detection performance for allergen-specific ige antibodies from korean allergic patients. | intermethod comparison between immulite 2000 chemiluminescent enzyme immunoassay (cleia) and the established cap test for allergen-specific ige (sige) has only been evaluated by a few studies. | 2009 | 19056369 |
| dermatophagoides farinae-specific immunotherapy in atopic dogs with hypersensitivity to multiple allergens: a randomised, double blind, placebo-controlled study. | a randomised, placebo-controlled, double blind study was conducted on 25 dogs that had atopic dermatitis, together with skin test reactivity and elevated serum ige to dermatophagoides farinae (df) and at least one additional allergen. dogs were treated with either a df-restricted immunotherapy solution (n=14) or a placebo (n=11) and evaluated 6 weeks and 3, 5, 7 and 9 months after the initiation of treatment using a clinical scoring system (sassad) and pruritus analogue scale scores. the df-rest ... | 2009 | 18653361 |
| characterization and comparison of commercially available mite extracts for in vivo diagnosis. | assessment of sensitization by allergen-specific ige testing and skin prick testing (spt) are primary tools in routine clinical diagnosis of allergies. to perform a correct diagnosis, it is critical that the allergen reagent used contains an adequate amount of all relevant components. this study aimed at evaluating commercially available mite extracts for in vivo diagnosis from eight manufacturers. | 2010 | 19796217 |
| saliva and serum eosinophil cationic protein in asthmatic children and adolescents with and without allergic sensitization. | saliva eosinophil cationic protein (ecp) is higher in asthmatic adults than in healthy ones. however, its relationship with asthma severity, other atopic conditions and allergic sensitization have not been reported. saliva collection is painless, readily acceptable to children and parents, and can be a potentially useful body fluid to measure asthma biomarkers. we recruited 102 physician-diagnosed young asthmatic subjects from outpatient clinics with change in fev(1) > or = 12% with inhaled salb ... | 2010 | 20100023 |
| prostaglandin e(2) exerts homeostatic regulation of pulmonary vascular remodeling in allergic airway inflammation. | nonselective inhibition of pg synthesis augments inflammation in mouse models of airway disease, but the roles of individual pgs are not completely clarified. to investigate the role of pge(2) in a mouse model of airway inflammation induced by a natural allergen, we used mice lacking the critical terminal synthetic enzyme, microsomal pge(2) synthase (mpges)-1. mice lacking mpges-1 (ptges(-/-) mice) and wild-type c57bl/6 controls were challenged intranasally with low doses of an extract derived f ... | 2010 | 20028661 |
| transmission electron microscopy studies in an experimental model of canine atopic dermatitis. | impairment of skin barrier function has been hypothesized in canine atopic dermatitis (ad). in this prospective, controlled study, the ultrastructure of the upper epidermal layers was investigated using an experimental model of canine ad. seven atopic beagles sensitized to dermatophagoides farinae and four healthy beagles were used as controls. both normal and atopic dogs were challenged with d. farinae for 3 days. clinical signs were scored and skin biopsies were taken from the inguinal area be ... | 2010 | 20042040 |
| relationship between squamous cell carcinoma antigen and the clinical severity of allergic rhinitis caused by dermatophagoides farinae and japanese cedar pollen. | allergic rhinitis is known to be related to the th2-type immune response, but no sensitive biomarker of severity yet exists. serum squamous cell carcinoma antigen (scca) is clinically used as a popular tumor biomarker. we have demonstrated that scca is related to allergic diseases such as asthma. the purpose of the present study was to clarify the relationship between allergic rhinitis and scca, which had not yet been investigated. | 2010 | 20128182 |
| clinical efficacy of house dust mite-specific immunotherapy in asthmatic children. | immunotherapy has been widely used in the treatment of allergic diseases. we evaluated the clinical efficacy of specific immunotherapy with extracts of dermatophagoides pteronyssinus (dp) and dermatophagoides farinae (df) in children with asthma. | 2010 | 20225533 |
| monoclonal antibodies against recombinant der f 3 reveal localization of der f 3 in the gut and faecal pellets of dermatophagoides farinae. | home dust mite derived materials are known to be a major source of problematic inhalant allergens. the aim of this study was to determine the localization of the group 3 allergen, der f 3, within dermatophagoides farinae, in order to assess the relative importance of excreted materials and nonexcreted body components as allergen sources. recombinant der f 3 (rder f 3) was expressed in bacteria and purified as an immunogen for production of monoclonal antibodies (mab) against it. dermatophagoides ... | 2010 | 20229323 |
| topical application of rehmannia glutinosa extract inhibits mite allergen-induced atopic dermatitis in nc/nga mice. | rehmannia glutinosa is known in asia as a traditional herbal medicine with anti-inflammatory properties. atopic dermatitis (ad) is an inflammatory skin disease associated with enhanced t-helper 2 (th2) lymphocyte responses to allergens that results in elevated serum ige levels and leukocyte infiltration. although some studies have shown that rehmannia glutinosa extract (rge) has anti-inflammatory and anti-allergic activities, these properties have not been demonstrated in ad. this study investig ... | 2010 | 21129471 |
| stratum corneum removal facilitates experimental sensitization to mite allergens in atopic dogs. | in humans with atopic dermatitis and in mouse models of ige-mediated allergic diseases, evidence is mounting that the stratum corneum (sc) provides an important barrier against environmental allergens. at this time, it is not known whether the sc has a similar role in dogs, especially in those with atopic dermatitis. the objectives of this pilot study were to determine whether sc removal led to earlier and stronger sensitization of atopic dogs to dermatophagoides farinae (df) house dust mites. f ... | 2010 | 21143539 |
| cloning, expression, and analysis of the group 2 allergen from dermatophagoides farinae from china. | to obtain the recombinant group 2 allergen product of dermatophagoides farinae (der f 2), the der f 2 gene was synthesized by rt-pcr. the full-length cdna comprised 441 nucleotides and was 99.3% identical to the reference sequence (genbank ab195580). the cdna was bound to vector pet28a to construct plasmid pet28a(+)-der f 2, which was transformed into e. coli bl21 and induced by iptg. sds-page showed a specific band of about 14kda in the hole cell lysate. as estimated by chromatography, about 3. ... | 2010 | 21152769 |
| [usefulness of total ige in predicting positive allergen specific ige tests in korean subjects]. | total ige levels in allergic patients tend to be higher than those in healthy individuals. we evaluated the usefulness of total ige levels in predicting positive results of allergen specific iges in multiple allergen simultaneous tests. | 2010 | 21157154 |
| effect of diesel exhaust particles on house dust mite-induced airway eosinophilic inflammation and remodeling in mice. | recent research has focused on the effects of ambient particulate pollution and much evidence has indicated that particulate pollution is associated with the onset of asthma and allergy; however, the effect of diesel exhaust particles (dep) on the development of allergen-induced airway remodeling has not been fully investigated in vivo. in the present study, we examined the effects of dep on dermatophagoides farinae allergens (der f)-induced asthma-like phenotypes in mice. mice were administered ... | 2010 | 20093792 |
| evaluation of serum specific ige for the diagnosis of allergic rhinitis with multi-allergens. | objective evaluation of allergic rhinitis (ar) requires in vivo and in vitro tests. in vitro tests are important to assist or ensure the main allergens in multi-allergen-sensitive patients. the aim of this study was to evaluate the utility of serum specific ige (sige) in the diagnosis of ar patients with multi-allergens in the chinese population. | 2010 | 21034593 |
| [compliance and safety evaluation of subcutaneous versus sublingual immunotherapy in mite-sensitized patients with allergic rhinitis]. | to investigate the safety profile of subcutaneous immunotherapy (scit) versus sublingual immunotherapy (slit) in patients with allergic rhinitis (ar) caused by house dust mites. the treatment compliance and related factors were also evaluated. | 2010 | 21055319 |
| group v secretory phospholipase a2 reveals its role in house dust mite-induced allergic pulmonary inflammation by regulation of dendritic cell function. | we have previously shown that group v secretory phospholipase a(2) (spla(2)) regulates phagocytosis of zymosan and candida albicans by a mechanism that depends on fusion of phagosomes with late endosomes in macrophages. in this study, we report that group v spla(2) (pla2g5)-null mice exposed to an extract of house dust mite dermatophagoides farinae had markedly reduced pulmonary inflammation and goblet cell metaplasia compared with wild-type (wt) mice. pla2g5-null mice had also impaired th2-type ... | 2010 | 20817863 |
| clinical and immunologic effects of sublingual immunotherapy on patients with allergic rhinitis to house-dust mites: 1-year follow-up results. | there have been no data on sublingual immunotherapy (slit) in asian patients with allergic rhinitis (ar) sensitized to house-dust mites (hdms). this study aimed to investigate the efficacy and immunologic change after 12 months of slit in korean patients. | 2010 | 20819465 |
| orally supplemented lactobacillus acidophilus strain l-92 inhibits passive and active cutaneous anaphylaxis as well as 2,4-dinitroflurobenzene and mite fecal antigen induced atopic dermatitis-like skin lesions in mice. | oral supplementation of lactic acid bacteria is a potential approach to the prevention and manipulation of allergic diseases such as atopic dermatitis. our previous report showed that heat-killed lactobacillus acidophilus strain l-92 (l-92) possessed anti-allergic properties, although its physiological function in atopic dermatitis has largely remained undefined. to evaluate the anti-allergic efficacy of l-92, we used four experimental animal models with the major features of atopic dermatitis a ... | 2010 | 20840151 |