Publications

eikenella corrodens: a new pathogen.	oral infections that result from trauma or dental manipulation are often thought to be of minor importance to the practicing clinician. the majority of oral infections respond well to treathis form of simple therapy is no longer as efficacious as it has been though to be. soment with the common antibiotics without the need for laboratory culture and sensitivity. there are instances, becoming increasingly frequent, when this form of simple therapy is no longer as efficacious as it has been though ...	1979	375152
techniques for fetotomy on schistosomus reflexus calves.		1979	257972
an explanation of therapeutic touch using the science of unitary man.		1979	259269
adenocarcinoma in a young rabbit (an atypical case).		1979	257971
inactivation of neurohypophysial hormone release in the rat by substitution of saline solution for drinking water [proceedings].		1979	522005
folic acid hypersensitivity and fever: a case report.	an apparent case of folic acid hypersensitivity and fever in a 36-year-old anephric man is reported. the patient first experienced pruritus when he received 1 mg of folic acid daily; the drug subsequently was discontinued. three months later, after administration of 1 mg of folic acid daily, the patient became febrile and pruritic. fever, generalized pain, chills, urticaria and pruritus persisted despite administration of acetaminophen/oxycodone tablets. leukocytosis was not present. challenge w ...	1979	517548
[the effect of calcitonin on contractile function of skeletal muscles (author's transl)].	the analgesic effect of calcitonin in osteoporosis has been considered to originate from its actions on bone metabolism. however, the author assumed a possible presence of other mechanism, since the analgesic effect of calcitonin manifests in an extremely early phase in which an increase in bone mass is hardly conceivable. namely, the author postulated that its analgesic effect is due to its actions on body trunk muscles, and investigated experimentally the effect of calcitonin on skeletal muscl ...	1979	528800
interhemispheric connections between primary visual areas in adult sheep and new-born lambs [proceedings].		1979	529138
abomasal hernia in a heifer.		1979	536041
protein turnover and cell-cycle initiation in yeast.		1979	387426
oxygen-dependent cleavage of dna by the 1,10-phenanthroline . cuprous complex. inhibition of escherichia coli dna polymerase i.		1979	387784
interference of azide with cysteine biosynthesis in salmonella typhimurium.	the growth inhibition of salmonella typhimurium azia mutants by sodium azide is reversed by cystine and related compounds. nadph-sulphite reductase (hydrogen-sulphide:nadp+ oxidoreductase; ec 1.8.1.2), an enzyme of cysteine biosynthesis, is inhibited in cell extracts by sodium azide. azib mutants which are able to grow in the presence of the inhibitor without cystine were isolated. about half of them were mapped in the cysk gene and have only residual activity of its product, o-acetylserine sulp ...	1979	387913
cultures from rat brain hemispheres enriched in oligodendrocyte-like cells.		1979	228801
studies in vivo with angiotensin i converting enzyme (kininase ii) inhibitors.		1979	228990
an effect of neostigmine on the response of the rat anococcygeus muscle to field stimulation [proceedings].		1979	497579
catabolite inactivation of gluconeogenic enzymes in mutants of yeast deficient in proteinase b.	strains of saccharomyces cerevisiae bearing nonsense mutations in the structural gene for proteinase b (ec 3.4.22.9) have been examined for the ability to make the transition from growth on acetate to growth on glucose and for the ability to inactivate three glucoeogenic enzymes during the transition because proteinase b has been proposed by others to be responsible for the inactivation of the three enzymes during the growth transition. the mutant strains make the growth transition normally. cat ...	1979	228302
use of a simultaneous ligating-dividing-stapling instrument for ovariohysterectomy.		1979	261005
[circulating system for performing immersion topical hypothermia of the myocardium].	a special circulating installation for topical hypothermia of the myocardium is proposed. an advantage of the installation is the possibility of the permanent controlled irrigation of the whole surface of the heart, especially of the posterior surface represented mainly by the left ventricle mass with the ice-cold solution.	1979	516281
the metabolism of nitrophenolic and 5-arylazorhodanine anthelmintics by ascaris suum, moniezia expansa and by mouse- and sheep-liver enzymes.	1. the anthelmintics disophenol (2,6-diiodo-4-nitrophenol), nitroxynil (3-iodo-4-hydroxy-5-nitrobenzonitrile) and nitrodan (3-methyl-5-(4-nitrophenylazo)rhodanine) were reduced in vitro to the corresponding amines by intact ascaris suum, moniezia expansa, by enzymes prepared from these helminths, and by mouse- and sheep-liver homogenates. helminth reductases required nadh2 and glutathione as cofactors and were inhibited about 50% by 2.0 x 10(-7) m allopurinol. azo bonds of nitrodan and its analo ...	1979	516789
au cell-surface antigen of human malignant melanoma: solubilization and partial characterization.	au antigen is defined by reactions of sera from patient au with cell-surface antigens of cultured autologous melanoma cells (sk-mel-28). past studies established that no available cell type other than au melanoma expressed au antigen. by use of antibody inhibition tests for antigen detection, limited papain digestion of au melanoma cells was found to result in the solubilization of au antigen along with beta2-microglobulin (beta 2m) and hla allogeneic and xenogeneic specificities. comparable pap ...	1979	313568
bioavailability of zinc in infant cereals.	the bioabailability of zinc in three cereals was determined by a rat assay, using total femur zinc as the indicator. the basal diet contained 25% egg white solids and 0.6 microgram zinc per gram. the infant cereals were included in the diets at three graded levels to supply 3--12 microgram zinc per gram. zinc sulphate was used as a standard source, with and without supplemental iron (185, 370, 555 microgram/g, respectively) at 3, 6 and 9 microgram zinc per gram with a view to determine the effec ...	1979	440632
[biomass accumulation by polyploid forms of candida guilliermondii yeasts].	under the action of a mitotic poison (acenaphthene), the haploid culture of candida guilliermondii assimilating n-alkanes yielded a polyploid form whose cells were four times larger, on the average, than in the haploid culture. when the pure culture was grown under stationary conditions in media with glucose, the economical coefficient, i. e. the ratio between the assimilated glucose and the accumulated biomass, was by 16, 47 and 157% higher in the polyploid culture than in the haploid one after ...	1979	470627
bilio-pancreatic bypass for obesity: 1. an experimental study in dogs.	bilio-pancreatic bypass is a new procedure that tries to obtain a maldigestion syndrome with selective malabsorption of the main high calorie foods. the operation consists of a gastric resection and division of the proximal jejunum just distal to the ligament of treitz. a gastroentero-anastomosis is then constructed using the distal end of the transected jejunum, while the proximal jejunum is anastomosed to the side of the distal ileum. an experimental study carried out on 12 dogs confirmed that ...	1979	497644
[behavior of the erythrocyte glucose-6-phosphate dehydrogenase in patients with functional thyroid disorders and in hyperthyroxinemic rats].	this paper deals with the activity of glucose-6-phosphate dehydrogenase in patients with hyper- and hypothyroidism as well as in hyperthyroxinaemic rats. the activity of glucose-6-phosphate dehydrogenase is enhanced in red blood cells of hyperthyreotic patients and hyperthyroxinaemic animals. the activity will be decreased to normal range in patients by administration of antithyreotic drugs, such as thiamazole. patients with hypothyroidism exhibit decreased enzymatic activity. it is suggested th ...	1979	538999
the effects of dopamine on neurones in the nucleus tractus solitarii and on the central control of blood pressure in the rat [proceedings].		1979	529063
somatic cell genetic analysis of transgenome integration.	the site of association of the human transgenome and host murine chromosomes was determined in several subclones of a stable human/mouse transformed cell line. chromosomes were transferred from each of three transformed subclones into chinese hamster recipient cells, and selection was applied for the expression of human transgenome-encoded hprt. a series of trispecific microcell hybrids was isolated and characterized for each subclone. evidence is presented that, within a given transformed subc ...	1979	545718
determination of 5-aminolaevulinic acid and porphobilinogen by high-performance liquid chromatography.	a strong anion-exchange column coupled to a strong cation-exchange column with acetate buffer as eluent or reversed-phase ion-pair chromatography on octadecylsilica with methanol-water containing 1-heptanesulphonic acid as the mobile phase is described for the simultaneous separation of 5-aminolaevulinic acid and porphobilinogen. the separation is applied to the development of a fast and simple method for determining the activity of the enzyme aminolaevulinic acid dehydrase in human erythrocytes ...	1979	546936
comparison of the metabolism of 2,4-toluenediamine in rats and mice.	the excretion, distribution, and metabolism of 2,4-toluenediamine (tda) have been compared in rats and mice. the elimination of tda metabolites into urine was faster and more complete in mice than in rats. however, the feces of rats accounted for a greater percentage of the dose in rats than in mice. the distribution of metabolites in tissues were considerably lower in mice than in rats. the major urinary metabolites observed in the rat were 4-acetylamino-2-aminotoluene, 2,4-diacetylaminotoluene ...	1979	547012
[exopolysaccharide and proteolytic enzyme synthesis by m-, s- and r-forms of mycobacterium lacticolum].	the composition of exocellular polysaccharides was studied in the m, s and r variants of mycobacterium lacticolum 104. the exoglycans of the m and s variants were found to be rather similar but differ considerably from the exoglycan of the r form. the polysaccharides of the m and s cells contained glucose, mannose, galactose, and pyruvic acid; the exoglycan of the r cells contained also the fourth sugar arabinose, but lacked pyruvic acid. the specific rotation of the polysaccharides from the m, ...	1979	470628
an evaluation of the bovine -- onchocerca gibsoni, onchocerca gutturosa model as a tertiary screen for drugs against onchocerca volvulus in man.	in this trial suramin, diethylcarbamazine, trichlorphon, levamisole, mebendazole, melarsonyl potassiu, hoechst 33258 and tinidazole were administered to cattle infected with o. gibsoni and o. gutturosa to determine the usefulness of this screen in predicting the effect of drugs in man against. o. volvulus except for melarsonyl potassium which was macrofilarticidal against o. gutturosa but not o. gibsoni when cattle were slaughtered 6 weeks after treatment. it was concluded that cattle infected w ...	1979	538819
[combined experimental exposure to subsonics and a superhigh frequency electromagnetic field].		1979	499821
kinetics of cl02 and effects of cl02, cl02-, and cl03- in drinking water on blood glutathione and hemolysis in rat and chicken.	since chlorination of drinking water produces organochlorinated substances (some possibly carcinogenic), the use of chlorine dioxide disinfectant would avoid halogenation. there is scarcely any data published on the effects of clo2 in drinking water on human or animal health. the kinetics of 36clo2 was studied in rats. radioactivity was rapidly absorbed from the gastrointestinal tract following the administration of (0.07 microci) 36clo2 orally. 36cl in plasma reached at peak at 1 hr. the half l ...	1979	547024
effect of dietary fats and triiodothyronine administration on the lipid components of serum and tissues in the rat.	twelve groups of rats were included in this study. six groups (3 males and 3 females) received high fat diets containing 20% of either peanut oil, maize oil or lard. the other six groups received the same diets plus triiodothyronine. triiodothyronine t3 added to diets containing peanut oil caused slight increase in total serum lipids in female rats, while in male rats serum total lipids were increased about 20-fold. t3 administration caused almost no change in aortic total and all lipid fraction ...	1979	549273
local immunity to bacteroides gingivalis in periodontal disease.	the histopathologic status of gingival tissue was assessed according to the criteria of page and schroeder.(5) rhodamine-labeled bacteria were used to assess the antigenic specificity of plasma cells in the tissue. examination of tissue sections revealed that 31.6% of plasma cells in the advanced lesions bound the labeled bacterium, compared with only 3.1% of the cells in the early lesions. these results indicate that local immunity to bacteroides gingivalis in greater in the more advanced than ...	1980	6159380
production of phenylacetic acid by strains of bacteroides asaccharolyticus and bacteroides gingivalis (sp. nov.).	strains of bacteroides asaccharolyticus and bacteroides melaninogenicus subspecies isolated from human and animal sources were examined for the production of phenylacetic acid. b. asaccharolyticus strains isolated from sites in humans and monkeys always produced phenylacetic acid. b. asaccharolyticus strains isolated from human nonoral sites consistently failed to produce this product. this metabolic difference correlates with the genetic dichotomy recently found to exist between oral and nonora ...	1980	6112236
antigenic studies of oral and nonoral black-pigmented bacteroides strains.	antigens of several oral and nonoral strains of bacteroides asaccharolyticus (proposed classification of oral b. asaccharolyticus, bacteroides gingivalis), bacteroides melaninogenicus subsp. intermedius, b. melaninogenicus subsp. melaninogenicus, and b. melaninogenicus subsp. levii were identified in soluble preparations obtained by sonication, autoclaving, and naoh treatment of whole bacterial cells. the sonicate preparations contained the most complete representation of soluble antigens using ...	1980	7216426
serum antibodies to oral bacteroides asaccharolyticus (bacteroides gingivalis): relationship to age and periondontal disease.	an enzyme-linked immunosorbent assay microplate method was used for measuring levels of antibody specific for the oral serotype of bacteroides asaccharolyticus (bacteroides gingivalis) in serum samples obtained from umbilical cords, infants, children, periodontally normal adults, and edentulous adults. serum from patients with various periodontal diseases, including adult periodontitis, localized juvenile periodontitis, generalized juvenile periodontitis, post-localized juvenile periodontitis, a ...	1981	7216444
microbial surface interactions: reduction of the haemagglutination activity of the oral bacterium fusobacterium nucleatum by absorption with streptococcus and bacteroides.	oral strains of fusobacterium nucleatum showed haemagglutination (ha) of sheep red blood cells and attachment of ha-active f. nucleatum fragments to other microorganisms allowed a means of studying microbial surface interactions. ha-active sonicated fragments (sf) prepared from f. nucleatum were mixed with whole cell suspensions of 48 bacterial strains and, after incubation, the whole cells were separated from the non-absorbed fragments by differential centrifugation. attachment of f. nucleatum ...	1981	7041865
polyclonal b-cell activation induced by extracts of gram-negative bacteria isolated from periodontally diseased sites.	the objective of this research was to determine whether gram-negative bacteria frequently isolated from periodontally diseased sites contained polyclonal b-cell activators. polyclonal b-cell activation, which results in nonspecific activation of multiple b-cell clones was analyzed by a hemolysis-in-gel assay designed to detect a broad range of antibody specificities. extracts from numerous bacterial strains, including bacteroides gingivalis, bacteroides melaninogenicus subsp. melaninogenicus, b. ...	1981	6975240
enzymatic characterization of some oral and nonoral gram-negative bacteria with the api zym system.	the api zym system (analytab products, plainview, n.y.), containing 19 chromogenic substrates, was utilized semiquantitatively to detect extracellular acid and alkaline phosphatases, aminopeptidases, proteases, esterase-lipase, phosphoamidase, and glycosidases in 128 oral and nonoral isolates of black-pigmented bacteroides, actinobacillus, haemophilus aphrophilus, capnocytophaga, fusobacterium nucleatum, wolinella recta, and veillonella parvula. in the black-pigmented bacteroides group of organi ...	1981	7026598
identification of bacteroides gingivalis by fluorescent antibody staining.	reactivity with the conjugates to the 4 serogroups a, b, c and c-1 of the former taxon bacteroides melaninogenicus and with antisera to b. gingivalis and to oral strains of b. melaninogenicus subsp. intermedius, was studied by fluorescent antibody staining (fas) on strains representative of the black-pigmented bacteroides: b. asaccharolyticus, b. melaningogenicus subsp. intermedius, b. melaninogenicus subsp. melaninogenicus, b. melaninogenicus subsp. levii, b. melaninogenicus subsp. macacae and ...	1981	7030174
an experimentally induced phlegmonous abscess by a strain of bacteroides gingivalis in guinea pigs and mice.	the virulence of b. gingivalis strain w83 was studied in an experimental animal model. cells grown overnight, washed and resuspended in broth, were injected intradermally or subcutaneously in the back of guinea pigs, rats and mice. this strain proved to be very virulent, causing a severe phlegmonous abscess in guinea pigs. also in mice, which are thought to be resistant to infections with black-pigmented bacteroides strains, the same type of infection could be induced. rats proved to be rather i ...	1981	7247390
black-pigmented bacteroides spp. in the human oral cavity.	five healthy children under 6 years of age, five healthy adults, and 10 adult periodontitis patients were examined for the prevalence and distribution of black-pigmented bacteroides in the oral cavity. a total of 13 samples was obtained from each individual, including four supragingival and four subgingival dental plaques, dental occlusal surface, buccal mucosa, dorsal tongue, tonsil, and whole saliva. black-pigmented bacteroides were recovered from nine adult periodontitis patients. healthy adu ...	1981	6111541
an internal deletion mutant of a myosin heavy chain in caenorhabditis elegans.	unc-54 i is the structural gene for a myosin heavy chain present in a major fraction of the total myosin of caenorhabditis elegans. the allele e675, which possesses a normal amount of myosin but fails to assemble thick filaments, has been shown previously to contain a novel heavy chain of molecular weight 2 x 10(5), shorter by 10(4) than the wild-type (n2) unc-54 gene product. the structural alteration of the e675 heavy chain is an internal deletion of 10(4) molecular weight near the cooh termin ...	1981	271956
[jean lhermitte (1877-1959)].		1981	351768
[a contribution to the history of czech-russian medical relations in the first half of the 19th century. iii. connections between czech and russian physicians in the scientific domain (author's transl)].		1982	347562
[attitudes of the population towards the dentist].		1982	272092
kinetic studies on an intramuscular iron-poly (sorbitol-gluconic acid) complex.	levels of iron and unsaturated iron binding capacity in serum and the renal excretion of iron were studied in 15 anaemic patients receiving ferastral. various dose schedules were used, 100 mg fe daily for 10 days, 200 mg fe daily for 5 days, and 500 mg fe twice at various intervals from 2 to 7 days. a continuous increase of iron in serum was seen after the doses 100 mg and 200 mg daily as well as after 500 mg given at intervals of 2 and 3 days. longer 500 mg dose intervals resulted in a fluctuat ...	1982	272032
bacteroides gingivalis antigens and bone resorbing activity in root surface fractions of periodontally involved teeth.		1982	6212659
effects of estradiol and progesterone on bacteroides melaninogenicus and bacteroides gingivalis.	bacteroides melaninogenicus subsp. intermedius increases in the subgingival microflora during pregnancy. these studies evaluated direct interactions between hormonal steroids and oral bacteroides species. resting cell suspensions of pure cultures of plaque organisms were incubated anaerobically with [14c]estradiol and [14c]progesterone. uptake of labeled compound per microgram of bacterial protein was determined by thin-layer chromatography and liquid scintillation counting. b. melaninogenicus s ...	1982	6119293
phagocytosis of bacteroides melaninogenicus and bacteroides gingivalis in vitro by human neutrophils.		1982	6124589
humoral immune response to oral microorganisms in periodontitis.	serum antibody titers from patients with periodontitis were compared with those from periodontally healthy subjects. with the micro-enzyme-linked immunosorbent assay, immunoglobulin g (igg), iga, and igm antibody titers to isolates of streptococcus sanguis, actinomyces viscosus, bacteroides gingivalis, bacteroides melaninogenicus subsp. intermedius, bacteroides gingivalis, bacteroides melaninogenicus subsp. intermedius, bacteroides ochraceus, and fusobacterium nucleation were determined. antibod ...	1982	6126434
cytotoxic activity of bacteroides gingivalis and bacteroides asaccharolyticus.	culture filtrates of all eight strains of bacteroides gingivalis and all five strains of b. asaccharolyticus were toxic for vero cells. cytotoxicity was in general greater with material from cultures of b. gingivalis than from b. asaccharolyticus but none of the culture filtrates from eight strains of b. melaninogenicus showed activity in this test. the toxic material was released during prolonged incubation and more detailed study of preparations from one strain indicated that it had a molecula ...	1982	6128424
influence of sublethal antibiotic concentrations on bacterial adherence to saliva-treated hydroxyapatite.	the influence of growth in the presence of sublethal concentrations of nine antibiotics on the ability of certain potentially odontopathic bacteria to attach to saliva-treated hydroxyapatite surfaces which mimic teeth was studied. cells of actinomyces viscosus ly7 and s2, bacteroides gingivalis 381, capnocytophaga ochraceus 6, and actinobacillus actinomycetemcomitans n27 attached in lower numbers to saliva-treated hydroxyapatite when grown in the presence of 50% of the minimum inhibitory concent ...	1982	6274799
enzymatic modification of bacterial receptors on saliva-treated hydroxyapatite surfaces.	certain properties of experimental pellicles formed by the adsorption of salivary components on hydroxyapatite surfaces change over time. to determine whether enzymes likely to be present in the oral environment could induce such changes, pellicles were treated with saliva which had been incubated for 18 h at 35 degrees c to promote the elaboration of microbial enzymes. this treatment markedly reduced the numbers of streptococcus mutans mt3 and jbp and s. sanguis fc-1 and c5 cells which attached ...	1982	6281193
inhibition of neutrophil chemotaxis by soluble bacterial products.	bacterial-neutrophil interactions may be critical determinants of virulence in periodontal diseases. this study was undertaken to examine the ability of major bacterial species from the human oral cavity to inhibit (1) peripheral blood neutrophil chemotaxis, (2) chemotactic formylmethionyl peptide binding, and (3) phagocytosis. included were cultured supernatants and sonic extracts obtained from strains of capnocytophaga, bacteroides gingivalis, fusobacterium nucleatum, bacteroides asaccharolyti ...	1982	6956714
characterization of bacteroides gingivalis by direct fluorescent antibody staining and cellular fatty acid profiles.	bacteroides gingivalis is a newly proposed species which includes strains isolated from the mouth. thirteen strains of b. gingivalis isolated from three geographic locations in the united states and france were examined with direct fluorescent antibody staining and analysis of total cellular fatty acids and compared with 16 strains of b. asaccharolyticus of nonoral origin by the same methods. bacteroides gingivalis strains reacted with the b. gingivalis conjugate (fluorescein isothiocyanate labe ...	1982	6178489
rapid identification of bacteroides gingivalis.	rapid colorimetric tests for trypsin and alpha-glucosidase are described for use in the identification of bacteroides gingivalis from dental plaque.	1982	7040453
api zym system for identification of bacteroides spp., capnocytophaga spp., and spirochetes of oral origin.	a total of 80 oral strains of bacteroides gingivalis, b. asaccharolyticus, b. melaninogenicus subsp. intermedius, b. melaninogenicus subsp. melaninogenicus, capnocytophaga, treponema denticola, and t. vincentii were characterized with the api zym system for 19 enzyme activities. comparison of anaerobic and aerobic incubation with nine reference strains of these organisms showed no important differences. the key differential tests for black-pigmented bacteroides strains and treponemes of oral ori ...	1982	6764781
butyrate: a cytotoxin for vero cells produced by bacteroides gingivalis and bacteroides asaccharolyticus.	culture filtrates of b. gingivalis and b. asaccharolyticus are cytotoxic for vero cells. it is shown that the cytotoxic effect is due to the butyrate concentrations present in the culture filtrates of these strains. this cytotoxic effect proved to be reversible. strains of the b. melaninogenicus subspecies intermedius and melaninogenicus did not produce butyrate and did not show cytotoxic activity towards vero cells. the significance of the production of toxic concentrations of butyrate for the ...	1982	7149698
long-wave uv light fluorescence for identification of black-pigmented bacteroides spp.	black-pigmented bacteroides strains were grown on blood agar, and the colonies were evaluated for fluorescence from long-wave uv light. most test strains of bacteroides melaninogenicus subsp. intermedius exhibited a brilliant red fluorescence. b. melaninogenicus subsp. melaninogenicus fluoresced mostly red-orange. bacteroides asaccharolyticus showed a yellow or red fluorescence. the intensity of the bacteroides fluorescence weakened when the black pigment of the colonies developed. in contrast, ...	1982	7161378
an approach to the definition of periodontal disease syndromes by cluster analysis.	clinical syndromes of 22 untreated patients with advanced destructive periodontal disease were analyzed using cluster analysis. clinical characteristics coded for each patient included age, sex, measures of gingival inflammation, plaque, suppuration, pocket depth, attachment level, extent and pattern of bone loss, rate of change in pocket depth, and correlation coefficients between certain clinical measurements. microbiologic features included darkfield enumeration of 10 morphologically distinct ...	1982	6960022
[studies of mixed anaerobic infections involving bacteroides gingivalis].	the infectiousness of several combinations of bacteria containing bacteroides gingivalis and other bacteria associated with periodontal diseases was evaluated by subcutaneous injection to guinea pigs. among the seven mixtures studied, only one permitted the development of an infection easily transmissible to a second guinea pig; this bacterial mixture was composed of b. gingivalis, fusobacterium nucleatum, eubacterium saburreum, and capnocytophaga ochracea (formerly bacteroides ochraceus). owing ...	1983	6883221
comparative hydrophobicities of oral bacteria and their adherence to salivary pellicles.	oral bacteria were found to differ in their surface hydrophobicities as determined by their ability to adsorb to hexadecane. strains of actinomyces viscosus, a. naeslundii, streptococcus sanguis, s. mitis, and bacteroides gingivalis proved highly hydrophobic. strains of b. intermedius, s. salivarius, s. mutans, and b. melaninogenicus were less hydrophobic, whereas strains of actinobacillus actinomycetemcomitans were hydrophilic. an overall correlation was noted between the adsorption of bacteria ...	1983	6885158
production of phenylacetic acid by bacteroides melaninogenicus ssp. intermedius serogroup c-1.	the methyl derivatives of broth cultures of black-pigmented bacteroides were examined by gas chromatography for production of phenylacetic acid. two serogroups of b. melaninogenicus ssp. intermedius described by lambe differed in the ability to produce phenylacetate. serogroup c failed to produce phenylacetic acid while serogroup c-1 produced small amounts of phenylacetate, which contributed 2.2-5.7% to the total nonvolatile acid profile. holdeman's newly proposed species "b. intermedius" and "b ...	1983	6133607
haemolysis of human erythrocytes by the fusobacterium nucleatum associated with periodontal disease.	fusobacterium nucleatum and bacteroides gingivalis are associated with oral disease. they both attach to haemagglutinate and human erythrocytes. experiments were performed to determine whether haemolysis would occur following attachment of strains of f. nucleatum and bacteroides species including b. gingivalis. the f. nucleatum strains consistently displayed both haemagglutination and haemolytic activity. the b. gingivalis strains and other bacteroides species displayed haemagglutination but no ...	1983	6579906
[glycylprolyl dipeptidylaminopeptidase in peritoneal exudates of guinea pig stimulated by bacteroides gingivalis].		1983	6582174
phenylacetic acid production by bacteroides gingivalis from phenylalanine and phenylalanine-containing peptides.	phenylacetic acid production and growth of bacteroides gingivalis were directly proportional to the trypticase content of the medium. l-phenylalanine enhanced phenylacetic acid production; 5 mg l-phenylalanine per millilitre stimulated maximum production of phenylacetic acid. peptides (2-4 amino acids) containing l-phenylalanine also stimulated phenylacetic acid production as did phenylpyruvic acid. resting cell suspensions of b. gingivalis also produced phenylacetic acid when incubated aerobica ...	1983	6652581
effect of anaerobic bacteria on killing of proteus mirabilis by human polymorphonuclear leukocytes.	killing of proteus mirabilis by human polymorphonuclear leukocytes was tested in the presence of different bacteroides species. in vitro experiments showed that anaerobic bacteria interfered with the killing of aerobic bacteria. however, this inhibitory effect was not a property of all bacteroides species. bacteroides gingivalis w83 showed the greatest inhibitory effect of the five bacteroides strains tested. killing of p. mirabilis was inhibited by the culture supernatant of b. gingivalis but n ...	1983	6133837
biological effects of a purified lipopolysaccharide from bacteroides gingivalis.		1983	6222173
nonspecific induction of immunoglobulin m antibodies to periodontal disease-associated microorganisms after polyclonal human b-lymphocyte activation by fusobacterium nucleatum.	the production of antibodies to oral bacteria was determined in lymphocyte cultures stimulated with sonicated fusobacterium nucleatum, a potent inducer of polyclonal b-cell activation. after 9 days the cultures were examined by a microenzyme-linked immunosorbent assay for immunoglobulin m (igm) antibodies to f. nucleatum, bacteroides gingivalis, actinomyces viscosus, and streptococcus sanguis. antibodies to these four bacteria were detected in cultures stimulated with polyclonal b-cell activatio ...	1983	6604024
gilles de la tourette's syndrome: clinical, genetic, psychologic, and biochemical aspects in 21 selected families.	eighty-one patients and relatives with tourette's syndrome, members of 21 selected families, participated in a 1-day clinic. in 12 of the 13 jewish families and six of the eight non-jewish families, there were multiple members with motor and vocal tics by observation or history. males predominated among those with persistent symptoms, but among those with spontaneous clearing, females predominated. twelve propositi had troublesome sexual and aggressive impulses, differing only quantitatively fro ...	1983	264605
adult respiratory distress syndrome. a need for comparative studies.		1983	348141
[review of digestive physiology].		1984	261481
collection and purification of stem cells and monocytes.		1984	263237
sexual excitement and response by imagery production.		1984	271146
planning and evaluation: the roles of the public and voluntary sectors.		1984	263260
effects of an immunomodulating agent on peripheral blood lymphocytes and subgingival microflora in ligature-induced periodontitis.	the peripheral blood lymphocyte populations and the subgingival levels of black-pigmented bacteroides species were monitored during the conversion of chronic gingivitis to progressing periodontitis in cynomolgus monkeys. in addition, the effects of an immunomodulating agent, the pentapeptide of thymopoietin (tp5), were determined. after the induction of active periodontitis, proportions of helper t-cells (okt-4 positive) decreased from 31.5 to 26.4%, and proportions of b-cells (surface immunoglo ...	1984	6234232
thiol-dependent collagenolytic activity in culture media of bacteroides gingivalis.		1984	6235351
proteoglycan production by chick embryonic chondrocytes is inhibited by culture filtrate of bacteroides gingivalis.		1984	6238146
degradation of the human proteinase inhibitors alpha-1-antitrypsin and alpha-2-macroglobulin by bacteroides gingivalis.	various strains of black-pigmented bacteroides species were grown on horse blood agar and suspended in human serum. after various times of incubation the effect of the bacteria on the serum was evaluated by polyacrylamide gel electrophoresis and "rocket" immunoelectrophoresis. the formation of trichloroacetic acid-soluble material in the suspensions and the capacity of the treated sera to inhibit the activity of trypsin were also determined. the two tested strains of bacteroides gingivalis (w83, ...	1984	6198282
morphological changes in the bacterium bacteroides melaninogenicus subspecies melaninogenicus isolated from the human mouth and grown in culture without added blood components.	striking polymorphism in the cellular morphology could be induced by removal of blood components from the liquid growth medium, but the cells of bacteroides gingivalis and b. melaninogenicus subspecies intermedius did not exhibit polymorphism when grown under these conditions. the major changes observed with light microscopy were an increase in cell size and extreme polymorphism. electron microscopy of the polymorphic forms of b. melaninogenicus subspecies melaninogenicus strains showed that suc ...	1984	6140911
purification and characterization of a novel type of fimbriae from the oral anaerobe bacteroides gingivalis.	fimbriae and their constituent protein (fimbrilin) were purified to homogeneity from the bacterial wash fluid and cell lysate fraction, respectively, of bacteroides gingivalis 381. fimbriae, observed by negative staining, were curly, single-stranded filaments with a diameter of ca. 5 nm. the apparent molecular weight of the fimbrilin was 43,000. fimbriae were resistant to sodium dodecyl sulfate denaturation at 70 degrees c. heating at 100 degrees c in sodium dodecyl sulfate was needed to complet ...	1984	6150029
immunoglobulin g response to subgingival gram-negative bacteria in human subjects.	serum and gingival crevicular fluid from normal healthy adults and patients with periodontitis were screened for immunoglobulin g antibodies to antigens from bacteroides gingivalis 381, bacteroides intermedius 24, bacteroides loescheii atcc 15930, fusobacterium nucleatum atcc 25586, eikenella corrodens 1073, actinobacillus actinomycetemcomitans atcc 29522, and capnocytophaga sp. strain m-12. immunoglobulin g antibody titers to the antigens were measured by an enzyme-linked immunosorbent assay. t ...	1984	6735473
[isolation and identification of bacteroides gingivalis in rapidly progressing periodontitis in koreans].		1984	6596344
[susceptibility of potential periodontopathic bacteria to metronidazole, spiramycin and their combination].	a total of 65 bacterial strains originating mostly from subgingival plaque were tested for their susceptibilities to metronidazole, spiramycin, and their combination, ornidazole, erythromycin and tetracycline by means of an agar dilution technique. all agents were active against all anaerobic gram-negative rods. bacteroides gingivalis and fusobacterium nucleatum showed marked susceptibility to metronidazole (mic less than or equal to 0.06 microgram/ml) whereas 4-64 micrograms/ml were required to ...	1984	6584423
[experimental periodontitis in hamsters induced by infection with bacteroides gingivalis].		1984	6591433
ability of various oral bacteria to bind human plasma fibronectin.	the present study describes the ability of various oral bacteria to bind human plasma fibronectin (pfn). avid binding of 125i-pfn was found for streptococcus mutans (serotypes a to h), streptococcus sanguis, group a streptococcus pyogenes and staphylococcus aureus, while other gram-positive bacterial species tested demonstrated only weak or negligible pfn binding ability. two gram-negative bacterial species, bacteroides gingivalis and escherichia coli, did not significantly bind pfn. 125i-pfn bi ...	1984	6390098
production of monoclonal antibodies that recognize specific and cross-reactive antigens of bacteroides gingivalis.	four monoclonal antibodies directed against bacteroides gingivalis were established by hybridoma technology. their reactivity against b. gingivalis, bacteroides intermedius, and bacteroides melaninogenicus was detected by the enzyme-linked immunosorbent assay. three monoclonal antibodies specifically reacted with b. gingivalis. one recognized antigens that were cross-reactive between b. gingivalis and b. intermedius. these monoclonal antibodies provide new tools for antigenic analysis of b. ging ...	1984	6480112
the bone-resorbing activities in tissue culture of lipopolysaccharides from the bacteria actinobacillus actinomycetemcomitans, bacteroides gingivalis and capnocytophaga ochracea isolated from human mouths.	the activities of lipopolysaccharides (lps) were assessed by measuring the calcium release from mouse calvaria in vitro and compared to that of lps from salmonella typhimurium. stimulation of bone resorption was maximal at an lps concentration of 10 micrograms/ml and at this dose all oral lps preparations showed similar levels of activity and less than that of lps from s. typhimurium. only s. typhimurium lps and b. gingivalis lps retained bone-resorbing activity at 0.1 microgram/ml. no bone-reso ...	1984	6362631
degradation in vivo of the c3 protein of guinea-pig complement by a pathogenic strain of bacteroides gingivalis.	the pathogenicity of five black-pigmented strains of bacteroides was tested in subcutaneously implanted teflon cages in guinea pigs. the tissue reaction around the cages was registered and the contents of the fluid of the cages were analyzed. two strains of b. intermedius produced a localized abscess around the cages, while one strain (381) of b. gingivalis and an asaccharolytic strain (bn11a-f) different from b. gingivalis did not induce any signs of abscess formation. one strain (w83) of b. gi ...	1984	6372060
metronidazole in periodontitis. i. clinical and bacteriological results after 15 to 30 weeks.	the statistical association of certain anaerobic organisms such as black pigmented bacteroides (bpb) species and spirochetes with clinical signs of active periodontitis, i.e. bleeding upon probing and bone loss, suggests that the lesions may actually reflect a "specific infection" involving these or unidentified species. all the known oral species of bpb and spirochetes are anaerobes which suggests that antimicrobial treatment directed specifically against anaerobes might be effective in periodo ...	1984	6376759
identification of bacteria in immunopathologic mechanisms of human dental pulp.	serial frozen sections from human dental pulp were used for the identification of oral bacteria in immunopathologic mechanisms. sera raised against actinomyces viscosus, a. naeslundii, bacteroides gingivalis, and b. melaninogenicus ss. intermedius, commercial sera against human immunoglobulins, complement, and monoclonal antibodies against human t cells were used in a double-staining immunofluorescence technique. sections of dental pulp from normal teeth showed no penetration of bacteria or bact ...	1984	6377171
detection and quantitation of bacteroides gingivalis in bacterial mixtures by means of flow cytometry.		1984	6084706
immunogold electron microscopy of surface antigens of oral bacteria.	colloidal gold particles 3-6 nm in diameter were prepared and stabilized with the igg fraction of polyspecific rabbit antisera produced against four different oral bacteria. the immunogold markers were used in homologous reactions to label the bacteria in a preembedding procedure for electron microscopy. an indirect immunofluorescence procedure was concurrently used to optimize the labelling conditions before observation with the electron microscope. the immunogold markers labelled fibrillar str ...	1984	6093974
immunologic profile of juvenile periodontitis. i. lymphocyte blastogenesis and the autologous mixed lymphocyte response.	studies of blastogenesis of lymphocytes in culture from juvenile periodontitis (jp) patients have been inconclusive. experiments demonstrating differences in lymphocyte blastogenesis to preparations of putative periodontopathogens in jp and phytohaemagglutinin (pha) were performed. variables in the blastogenesis assay system recently reported were controlled which included using a range of cell and activator concentrations, incubation times of 3, 5 and 7 days, conical-bottomed microtest wells an ...	1984	6592318
actinobacillus actinomycetemcomitans and bacteroides gingivalis in advanced periodontitis in man.		1984	6386438
osteomyelitis in dogs and cats caused by anaerobic bacteria.	localised osteomyelitis was diagnosed in 2 dogs and 2 cats. the disease was caused by fight wounds in 3 cases. radiographic examination demonstrated a circumscribed zone of cortical bone lysis, sequestra and periosteal new bone. each case was treated surgically by sequestrectomy and debridement. infection was due mainly to anaerobic bacteria. the pathogenic bacteria isolated from the lesions of dogs were actinomyces viscosus, fusobacterium nucleatum and bacteroides spp, and from the lesions in c ...	1984	6732670
colonization of the subgingival area by bacteroides gingivalis.	the initial event in colonization of the subgingival area by b. gingivalis is its attachment to host cells and gram-positive bacteria in pre-formed plaque. the level of b. gingivalis is partly governed by products of other plaque bacteria, especially by sanguicin. once b. gingivalis resides in its nidus and starts to proliferate, expulsion of pre-existing residents may occur, especially of attached gram-positive bacteria, through the inhibitory action of the b. gingivalis product, hematin. the b ...	1984	6583244
fractionation of hemagglutinating and bacterial binding adhesins of bacteroides gingivalis.	an outer membrane complex containing hemagglutinating and bacterial aggregating activity has been isolated from bacteroides gingivalis. examination of the membrane material by biochemical analysis, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and immunological means revealed that the crude outer membrane preparation contained three major proteins and a lipopolysaccharide population that displayed size heterogeneity. at least two membrane proteins as well as the lipopolysaccharide w ...	1984	6746097