Publications

fowl cholera: cross-protection induced by pasteurella multocida separated from infected turkey blood.	crude liver homogenates from turkeys that died of fowl cholera produced by serotype 1 or 3 pasteurella multocida induced cross-protection. pasteurella multocida harvested from the blood of infected turkeys by a centrifugal technique were as immunogenic as the liver homogenates. neither bacterial cell-free blood plasma nor washed p. multocida from infected turkeys induced significant cross-protection. blood plasma containing p. multocida induced significant cross-protection. pasteurella multocida ...	1979	526205
isolation and characterisation of bacteria from abscesses in the subcutis of cats.	thirty-six closed abcesses in the subcutis of cats were examined. of 168 bacterial strains isolated, 121(72%) were anaerobes and 47 (28%) were facultative anaerobes. twenty-six abscesses contained mixtures of facultative anaerobes and anaerobes, six contained anaerobes only and four contained facultative anaerobes only. bacteriodes was the genus most commonly isolated (28.6% of all isolates) followed by fusobacterium (19.0%) and pasteurella (multocida) (13.1%). peptostreptococcus anaerobius was ...	1979	458840
human pulmonary pasteurellosis.	pasteurella multocida causes hemorrhagic septicemia in many domestic and wild animals. the most common human infection with p multocida is a local cellulitis following animal-inflicted wounds, preponderantly cat bites and scractches. the typical clinical manifestations and complications have been well described previously. we present three cases of pulmonary pasteurellosis that were recently evaluated by the infectious diseases service at barnes hospital. in three additional cases, the technolog ...	1979	582610
fever and reduced iron: their interaction as a host defense response to bacterial infection.	when rabbits are infected with pasteurella multocida, the concentration of iron in their plasma decreases and their rectal temperature rises. to determine whether the rise in body temperature (fever) and the fall in plasma iron may be a coordinated host defense response, pasteurella multocida were grown in vitro at various temperatures and iron concentrations. at afebrile temperatures the bacteria grew equally well at low or high concentrations of iron. however, when the temperature of the bath ...	1979	760197
chromosomes in malignant lymphomas (study on short-term lymph node cultures).	in 15 cases, chromosome studies were performed in short-term lymph node cultures, using the banding technique. clonal aberrations were found in two cases of hodgkin's disease and in two of lymphosarcoma. in agreement with earlier observations, the cases of lymphosarcoma with abnormal karyotypes proved hyperdiploid. no chromosomal aberrations were found in three cases of reactive lymphoreticular hyperplasia.	1979	352853
simultaneous placement of multiple porcelain veneers.	although laminate veneers are usually placed individually in order to avoid bonding the anterior teeth together, an alternate technique is presented. the technique described is efficient and time-saving.	1980	2134002
five years of adjuvant treatment of osteosarcoma: more questions than answers.		1980	273478
effects of n-alkanols on the calcium current of intracellularly perfused neurons of helix aspersa.	the effects of n-alkanols on the calcium current (ica) were studied in molluscan neurons perfused intracellularly and voltage clamped using a suction pipette technique. all n-alkanols employed in this experiment (methanol, ethanol and butanol) decreased the peak amplitude of ica and caused acceleration of the decay of ica in a dose-dependent manner at all membrane potentials. the concentrations of n-alkanols required for these actions decreased as the hydrocarbon chain increased in length. the r ...	1980	2425895
the response of broiler breeder chickens to parenteral administration of avirulent pasteurella multocida.	broiler breeder chickens were exposed to avirulent pasteurella multocida at 14, 22, and 34 weeks of age either by stick wing 1 to 3 times or subcutaneously 3 times. fowl pox vaccine was mixed with the first p. multocida exposure in some groups. exposure did not impair egg production or hatch of fertile eggs. challenge with pathogenic p. multocida serotype 1 at 68 weeks indicated that exposure to avirulent p. multocida 2 or 3 times provided better protection than 1 exposure. mixing fowl pox vacci ...	1980	6255928
hyaluronidase production by type b pasteurella multocida from cases of hemorrhagic septicemia.	seventy-four cultures of pasteurella multocida representing all four capsular types, a, b, d, and c, from various animal species and diseases were examined for the production of hyaluronidase by two procedures. in one, hyaluronidase production was determined by the depolymerization of streptococcal capsular hyaluronic acid, and in the other, production was determined by degradation of sodium hyaluronidate in a solid culture medium. hyaluronidase production was only demonstrated in the 13 type b ...	1980	6766466
serological relationship between strains of pasteurella multocida.	the serological inter-relationships of twenty four strains of pasteurella multocida represented by 11 reference strains, each representing a different serogroup, and 13 strains from cattle with hemorrhagic septicemia were determined by agglutination and gel diffusion tests. there was agreement between the results of the two procedures indicating that both tests were probably employing the same antigen. although all strains had strong serogroup-specific agglutinating and precipitating properties, ...	1980	6769638
physiological and serological characteristics of 48 pasteurella multocida cultures from rabbits.	forty-eight pasteurella multocida cultures collected from rabbits over a 56-year period were examined to determine their physiological characteristics and to determine their serological types in the gel diffusion precipitin test. generally, the physiological characteristics from 30 tests were typical for p. multocida. there were a few atypical variations in the fermentation of lactose and maltose and variations in trehalose, dulcitol, xylose, sorbitol, and glycerol. seven cultures did not produc ...	1980	6776138
preliminary field trails with a streptomycin-dependent vaccine against haemorrhagic septicaemia.	in two trials, 68 cattle and buffalo calves, four to 10 months of age, were vaccinated with a vaccine containing a live streptomycin dependent mutant of pasteurella multocida type b, isolated in sri lanka. immunity was assessed using the passive protection test in mice with cattle and buffalo sera before and two or three weeks after vaccination. a single dose of vaccine conferred immunity in 66.6 to 83.3 per cent of cattle and 100 per cent of buffalo calves. a booster dose given three weeks late ...	1980	6776679
pasteurella multocida: plasma lysozyme in bacteremic and lipopolysaccharide-exposed turkeys.	plasma lysozyme was measured in turkeys with experimental fowl cholera produced by either of two serotypes of pasteurella multocida. lysozyme was not detected in preexposure plasma, whereas plasma sampled when turkeys were terminally bacteremic contained 7.0-7.5 microgram of lysozyme/ml. plasma lysozyme was measured in turkeys inoculated intravenously with p. multocida lipopolysaccharide (lps). turkeys inoculated with 10 microgram of lps produced plasma lysozyme detectable for 2 hr after inocula ...	1980	6777438
type e pasteurella multocida associated with haemorrhagic septicaemia in zambia.		1980	6777965
production and characterization of streptomycin dependent mutants of pasteurella multocida from bovine haemorrhagic septicaemia.	a large number of streptomycin dependent mutants were produced from bovine haemorrhagic septicaemia strains of pasteurella multocida. the mutants required a minimum concentration of 25-50 microgram/ml streptomycin for growth and tolerated a concentration of 200 mg/ml. these mutants were avirulent to mice, when inoculated alone, but some mutants killed mice when inoculated with streptomycin. biochemically all mutants were uniform and similar to the wild type. most mutants were stable, but a few p ...	1980	6778598
facultative pasteurella ophthalmitis in hooded lister rats.	hooded lister rats were found to exhibit symptoms of mycoplasma pulmonis infection. during the course of this chronic respiratory disease they developed ophthalmia and conjunctivitis which proved to be an opportunist infection with pasteurella multocida. the severity of disease varied in individual rats, newborn rats entirely escaping infection. all cases responded to treatment with appropriate topical antibiotic and no sequelae were observed.	1980	6970299
[recommendations for isolation and differentiation of pasteurella multocida].		1980	7006554
shipping fever pasteurellosis and salmonellosis prophylaxis.	a water-in-oil emulsion adjuvanted combination shipping fever bacterin containing pasteurella multocida, p hemolytica, salmonella typhimurium and certain other species was effective in field use as a prophylactic agent against shipping fever pasteurellosis and salmonellosis. in trials using ranch calves it produced a greater antibody response than a comparable aluminum hydroxide adjuvanted bacterin. in critical 30-hour postvaccination challenge mouse tests it was superior to the conventional typ ...	1980	7007862
cultivation of pasteurella multocida under agitated conditions, in sterilized and non-sterilized media.		1980	7027390
cellular fatty acid composition of haemophilus species, pasteurella multocida, actinobacillus actinomycetemcomitans and haemophilus vaginalis (corynebacterium vaginale).	the fatty acid composition of 35 haemophilus influenzae strains was found to be grossly similar and characterized by relatively large amounts of 14:0, 3-oh-14:0, 16:1 and 16:0. the three c18 fatty acids 18:2, 18:1 and 18:0 were also present, but in much lower concentrations. this general pattern was also found for most of the other species of haemophilus examined (h. aegyptius, h. aphrophilus, h. canis, h. gallinarum, h. haemolyticus, and h. parainfluenzae). small but distinct quantitative discr ...	1980	6990689
the effects of laboratory animal diets on the potency tests of bacterial vaccines.	comparative studies of the responses elicited by mice fed on pcd and ffg diets to a number of bacterial vaccines have shown a significant reduction in the immune response to tetanus toxoid but not to clostridium septicum toxoid and increased resistance to challenge with e. coli and syngeneic tumour cells but not to pasteurella multocida. these differences cannot readily be explained in terms of differences between the identifiable constituents of the diets and illustrte the dangers of vaccine po ...	1980	6995215
a study on bacteriocin typing of avian strains of pasteurella multocida.	in two groups, each containing 56 pasteurella multocida strains of avian origin, the percentage of multicin-producing strains was 80.4 and 71.4. in two groups containing 46 and 58 isolates tested for sensitivity to multicins, 82.6% and 62.1% respectively were listed as indicators. p. multocida strains producing bacteriocins were active on a range of 1-33 indicators. a preliminary multicin typing system was set up with the use of eight selected indicators; 52% of multicin-producing strains acted ...	1980	7052231
isolation of group ef-4 bacteria in australia.	a bacterial strain isolated from dog-bite wound was identified as belonging to a group which is so far unnamed but which has been tentatively designated group ef-4 by workers at the center for disease control, atlanta, usa. although this appears to be the first reported isolation in australia of a strain belonging to this group, it is possible that strains of group ef-4 are not infrequently recovered from dog-bite wounds but, when they are, they may either not be identified or be dismissed as sk ...	1980	6932836
[drug-resistance markers from salmonellae in pasteurella multocida].	a transfer of resistance was effected of s. haidelberge strain, having 7 medicinal resistance markers, onto 2 pasteurella multocida strains no. 10 and vladislavovo. in strain no. 10 were found 20% of recombinations, whereas in vladislavovo their number was 10%, hence the different pasteurella strains can be recipients at a higher or lower degree. the recombinations obtained are not stable and during their short conservation in bouillon they spontaneously get rid of the markers of resistance acqu ...	1980	6940316
prophylactic antibiotics in common dog bite wounds: a controlled study.	a double-blind prospective study of 98 patients was carried out, but 57 (58%) returned for follow-up and form the basis of this report. wound irrigation and debridement were found to be important in reducing infection. hand wounds were most likely to become infected; face and scalp wounds were at low risk. puncture wounds became infected more often than did lacerations. suturing wounds did not increase the likelihood of infection except on the hand, where the data were equivocal. prophylactic pe ...	1980	6902630
human pasteurellosis: the first reported case of pasteurella multocida septicemia and peritonitis during pregnancy.		1980	7191207
a vaccine strain of pasteurella multocida obtained by mutagenesis.	a virulent avian septicemia strain of pasteurella multocida (p. multocida) serotype 1 was mutagenized with n-methyl-n'-nitro-n-nitroso guanidine. a selection procedure was devised to isolate mutants with changed growth properties. mutants were isolated that had either prolonged doubling time or temperature sensitivity for growth at 41 degrees c. a correlation was observed between growth properties in vitro and multiplication in vivo. mutants defective in growth were avirulent. a positive correla ...	1980	7208508
evaluation of an induced pasteurella multocida swine pneumonia model.	a reproducible swine pneumonia model was developed, utilizing pasteurella multocida (strain msu 7) and a rapid endotracheal inoculating technique. the model provided a means of testing various factors, such as therapeutic agents that may influence the course of pulmonary pasteurellosis. in a series of experiments, 81 infected nonmedicated pigs had a morbidity of 96% and a mortality of 22%. pasteurella multocida was isolated from 62% of the lungs at necropsy; 86% of the lungs had gross lesions ch ...	1980	7212419
immunity induced in mice by pasteurella multocida strains isolated from rabbits.		1980	7223182
lack of cross-immunity among pasteurella multocida type a strains.	active and passive protection studies in mice using sheep antisera revealed that the immunological relationship among pasteurella multocida type a strains could not be correlated with their serological relationship as determined by a haemagglutination or an agglutination test. furthermore, strains possessing similar phenol extractable antigens or heat stable antigens did not provide complete cross-protection. the conclusion was reached that immunity to p. multocida type a strains is induced by a ...	1980	7231921
antigenic analysis if pasteurella multocida (serotype 1) by crossed immunoelectrophoresis: characterization of whole cell associated antigens.	crossed immunoelectrophoresis and other related quantitative immunoelectrophoresis techniques have been used to elucidate the antigenic complexity of a reference preparation of capsular extract, potassium thiocyanate extract, lipopolysaccharide, heat-stable antigens, and free endotoxin from pasteurella multocida serotype 1. the reactions of these cellular fractions in crossed immunoelectrophoresis, with reference anti-whole cell immunoglobulins disclosed five antigens in the capsular extract, se ...	1980	7237264
pasteurella multocida infection; report in urban setting and review of spectrum of human disease.		1980	6999394
haemagglutinating properties of pasteurella multocida type a strains isolated from rabbits and poultry.	thirty-one type a strains of pasteurella multocida isolated from rabbits and poultry were able to agglutinate red blood cells (rbc) from human group o donors. except for human rbc from group b which were also agglutinated by 3 strains, neither group a nor rbc from sheep and rabbits were agglutinated. haemagglutination was mannose-resistant, and the two techniques used detected unrelated activities. one as tested by a slide haemagglutination (mrsh) test was common to most (31 out of 34 strains) c ...	1980	7191685
mammalian bite wounds.	clinical data were collected prospectively from a series of 160 patients presenting with mammalian bite wounds. anaerobic and aerobic cultures were prepared from sterile swabs placed in 65 bite wounds prior to cleansing. infection was noted in 11 of 22 cat bites, six of 37 human bites, three of 80 dog bites, and in none of the 21 bites caused by other mammals. pasteurella multocida was recovered from six infected cat and dog bites, all of which developed infection within 24 hours of injury. stap ...	1980	7356213
isolation of pasteurella multocida from sporadic outbreaks of bovine pasteurellosis in assam.		1980	7361430
[carbohydrate metabolism in pasteurella multocida].		1980	7210706
an outbreak of pasteurellosis in kano zoo.	an outbreak of pasteurellosis caused by pasteurella multocida is reported in which six elands (taurotragus oryx), a gnu (connochaetes taurinus albojubatus), a zebra (equus bruchelli), five kangaroos (macropus rufus), an ostrich (struthio camelus camelus) and a bateleur eagle (terathopius ecaudatus) died in kano zoological gardens toward the end of the rainy season of 1978. confirmation was based on cultural isolation of p. multocida. analysis of likely factors that could have contributed to the ...	1980	7373722
late postoperative infection caused by pasteurella multocida.	pasteurella multocida is often found in local infections after animal bites. septic conditions however are rare. a case of late infection by p. multocida at the site of the osteosynthesis 1 year after a primarily healed pertrochanteric fracture is described. the patient had a cat. after extraction of the plate and screws and treatment with penicillin the infection healed uneventfully.	1980	7375827
[pasteurella multocida infections in birds following cat bites (author's transl)].	infection with pasteurella multocida caused by bites has been known for several decades. cats are an important factor in pasteurella multocida infection. considerable numbers of victims are 'rescued' from the mouths of cats and submitted to bird reception centres for treatment. a number of bird shelters sent birds in this condition to the present authors for closer examination. the majority of birds caught by cats die. the mortality rates in shelters were reported to be 30, 90, 99 and one hundre ...	1980	7376178
pasteurella multocida septicaemia complicating felty's syndrome: a case report.	a patient with felty's syndrome complicated by septicaemia due to pasteurella multocida is presented. disease caused by this organism is unusual in humans and its occurrence in the absence of trauma, as was the case in our patient, even more so.	1980	7404234
[use of an oxytetracycline nasal spray in the treatment and prevention of atrophic rhinitis in piglets (author's transl)].	the piglets of two multiplier herds (m and b) showing clinically apparent atrophic rhinitis (ar) were treated by the nasal-spray method. a solution of oxytetracycline hydrochloride (otc, 50 mg/ml.) was used as a spray fluid. the course of the disease in the herds was followed by studying the development of foreshortening of the upper jaws in the heads. brachygnathia superior (bs), from the eighth to tenth week of life. efforts were made to gain an impression of the effects of treatment on the fr ...	1980	7404566
the interaction of haemophilus parahaemolyticus and pasteurella multocida in the respiratory tract of the pig.		1980	7407539
[amino acid metabolism in pasteurella multocida studied using thin-layer chromatography].	amino asid metabolism was studied by thin layer chromatography in 25 pasteurella multocida strains isolated from various manifestations of the disease chicken septicemia. six amino acids were used: dl-ornithin, l-cystein, l-asparagin, dl-serin, l-arginin and acidum glutaminicum. the pasteurella strains studied include in their metabolism the amino acid asparagin, but serin and cystein are excluded. the strains isolated from birds suffering from acute and atypical septicemia do not metabolize orn ...	1980	7414930
pasteurella multocida septicemia and peritonitis in a cirrhotic cock trainer with a pet pig.		1980	7421926
[some aspects of the study of atrophic rhinitis in pigs (author's transl)].	atrophic rhinitis is the most dreaded nasal inflammatory lesion described in pigs. experimental studies showed that this form of rhinitis may be induced by inoculation of the bacterial species bordetella bronchiseptica (bb) and/or pasteurella multocida (pm). it is apparent from studies on ar in the central veterinary institute during the past few years, that these species of bacterium may be classified into ar-pathogenic and ar-non-pathogenic micro-organisms. the significance of these findings i ...	1980	7423466
[effect of iron on the virulence of pasteurella multocida].		1980	7424351
articular and skeletal infections caused by pasteurella multocida.	pasteurella multocida infections of joints and bones generally occur in individuals who have contact with cats or dogs. osteomyelitis usually follows penetrating trauma such as an animal bite. septic arthritis tends to occur in patients who have preexisting inflammatory joint disease, especially if a systemic condition which is known to predispose to infection is present. the principles of therapy for septic arthritis or osteomyelitis are no different from those which have been established for o ...	1980	7434048
aerosol transmission of pasteurella multocida in turkeys.	in three incidents, uninoculated turkeys separated from pasteurella multocida-inoculated turkeys died of fowl cholera; it was inferred that the pathogen was transmitted by aerosol through the circulating air. uninoculated and inoculated turkeys were separated by a solid partition and wire netting, and were handled separately. turkeys were inoculated with a highly virulent strain of p. multocida, which induced the pulmonary form of fowl cholera. in four of the five uninoculated turkeys that died, ...	1980	7271632
accidental penetration of hands with virulent and avirulent pasteurella multocida of turkey origin.		1980	7271639
effects of high and low environmental temperatures on clinical course of fowl cholera in turkeys.	turkeys inoculated with pasteurella multocida either in the palatine air spaces or via drinking water were maintained t high (33.4-37.4 c), low (2.6-5.3 c), and moderate (19.8-22.4 c) temperatures in temperature-controlled chambers to determine the influence environmental temperature had on the pathogenesis of fowl cholera. in inoculated turkeys maintained at high temperatures, there was a delay in the onset of depression and, in most instances, in mortality in relation to those at low or modera ...	1980	7271640
preliminary clinical pharmacological investigations of tylosin and tiamulin in chickens.	the minimal inhibitory concentrations (mic) of tiamulin and tylosin for mycoplasma, gram-positive, and gram-negative micro-organisms isolated from chickens were determinated by the agar dilution method. median mic values for tiamulin against mycoplasma gallisepticum (0.05 microgram/ml) and mycoplasma synoviae (0.10 microgram/ml) were 2 to 4 times lower than the corresponding values for tylosin. tiamulin was also slightly more effective in vitro in inhibiting escherichia coli, pasteurella multoci ...	1980	7444918
virulence and morphology of pasteurella multocida of avian origin.	the virulence of 100, 54 and nine avian isolates of pasteurella multocida for mice, chickens and turkey poults respectively was assessed and rated on a scale from 0 to 5. cellular and colonial morphology of the bacteria was examined after mouse passage. there was evidence of a considerable range in the virulence of the isolates for the test species, but no correlation between cellular or colonial morphology and virulence was detected. the results obtained are discussed in relation to general epi ...	1980	7445378
orally administered tylosin for the control of pneumonia in neonatal calves.	the effectiveness of orally administered tylosin tartrate for the control of naturally occurring pneumonia was determined in 287 neonatal calves. tylosin tartrate was mixed with reconstituted milk replacer at the time of feeding. daily doses of 1.0 g (0.5 g bid), 2.0 g (1.0 g bid) and 4.0 g (2.0 g bid) were evaluated for periods ranging from seven to 28 days. tylosin at the optimum dose of 2.0 g daily reduced mortality to 12 out of 95 (12.6 per cent) compared to 38 out of 89 (42.7 per cent) in t ...	1980	7445393
plasma corticosterone concentrations in turkeys inoculated with pasteurella multocida and maintained at high and low environmental temperatures.	radioimmunoassay was used to determine plasma corticosterone concentration (pcc) in turkeys inoculated with pasteurella multocida via either the palatine air spaces or the drinking water and maintained at high (33.4-37.4 c), low (2.6-5.3 c) and moderate )19.8-22.4 c) temperatures in temperature-controlled chambers. in uninoculated turkeys maintained at high temperatures, the pcc was generally lower than in turkeys maintained at moderate temperatures, whereas the opposite occurred in turkeys main ...	1980	7271641
[problems relating to the use of radioactively labelled bacteria in animal experiments. 3. distribution of activities in mice, following parenteral administration of pasteurella multocida labeled with various radionuclides].	when radioactively labelled fully developed pasteurella (p.) multocida antigens were parenterally applied to mouse, through intravenous, intraperitoneal or subcutaneous routes, activity distribution was found to depend both the technique of application and the radionuclide used. this has given rise to the conclusion that activity distribution could be equated with whole-germ distribution only under certain conditions. experimental antigen distribution, accordingly, reflected a complex process in ...	1980	7447600
chemotaxis of fowl monocytes to pasteurella multocida and associated antigens.	the interaction of monocytes and serum from pasteurella multocida-immunized and non-immunized turkeys and chickens was studied for their chemotactic activity to lipopolysaccharide, free endotoxin, and p. multocida whole cells. chemotactic factors were released from the interaction between either normal sera or antisera and the bacterial antigens. heating of the sera affected their ability to interact and release chemotaxins. heated normal sera were ineffective and heated antisera were less effec ...	1980	7447836
experimental atrophic rhinitis in gnotobiotic pigs.	twenty-nine caesarian derived colostrum deprived germfree pigs were reared in isolators in groups of three to four per isolator. at seven days of age each group was inoculated intranasally with one of four strains of bordetella bronchiseptica (designated b, j, l and 55b), or pseudomonas aeruginosa or a mucoid strain of escherichia coli, all previously isolated from nasal mucus of pigs affected with clinical atrophic rhinitis. another group was inoculated simultaneously with b. bronchiseptica b a ...	1980	7448626
a strain of pasteurella multocida associated with infections in rabbit colonies.	pasteurella multocida was isolated from 4 conventional rabbit colonies. amongst 51 isolates, 48 (94%) belonged to a group of strains with similar morphological, cultural, biochemical and antigenic characteristics; they were named for convenience lo strains and gave rise to local or ascending infections. all lo strains were found to be a new serotype, but 8 of them had additional antigenic factors characteristic of known serotypes. the other 3 isolates (6%) were identified as serotype 3, known to ...	1980	7464023
pasteurella multocida infection of poultry farm rats.	thirty-four rat carcases from 11 poultry farms were examined for the presence of pasteurella multocida; 14 out of 34 (41 per cent) proved positive after mouse inoculation, compared with five out of 34 (14 per cent) using media alone. no salmonellae were recovered from 27 rat carcases using enrichment media. poultry pasteurellosis was present on two farms with infected rats and the same serotype was present in rats and poultry in those cases.	1980	7467090
influence of pasteurella multocida and high and low environmental temperatures on adrenals and bursa of fabricius in turkeys.	the morphologic changes in the adrenals and bursa of fabricius were evaluated from turkeys inoculated with pasteurella multocida either in the palatine air spaces or via drinking water and maintained at high (33.4-37.4 c), low (2.6-5.3 c), and moderate (19.8-22.4 c) temperatures in temperature-controlled chambers. there was a slight hyperplasia of the adrenal cortical cells and a hypertrophy of the nuclei in the uninoculated turkeys maintained at both high and low temperatures, but these changes ...	1980	7271642
antigenic analysis of pasteurella multocida (serotype 1) by crossed immunoelectrophoresis: characterization of cytoplasmic and cell envelope associated antigens.	the application of crossed immunoelectrophoresis to the analysis of a reference cytoplasm and cell envelope preparation from pasteurella multocida serotype 1 revealed antigenic complexity not previously found. at least 55 cytoplasmic and 19 cell envelope antigens were clearly distinguished. variation of anticytoplasm immunoglobulin concentration was a major determining factor in resolving the maximum array of cytoplasmic antigens. the use of intermediate gel modification of crossed immunoelectro ...	1980	7397610
dog bite wounds and infection: a prospective clinical study.	we prospectively studied 26 patients with 27 dog bite wounds who sought medical attention in the emergency department. two distinct populations were found (fishers exact test, p less than or equal to 0.001): 1) those who presented 8 hr to 12 hr post-injury were concerned about rabies or tetanus or surgical wound repair; and 2) those who presented more than 12 hr post-injury were concerned with infection. there was no difference (p > 0.05) in the bacteriology of the two groups. of all wounds, 74% ...	1980	7425403
a streptomycin dependent live pasteurella multocida vaccine for the prevention of rabbit pasteurellosis.	a culture of pasteurella multocida was isolated from a rabbit exhibiting clinical signs of respiratory pasteurellosis. organisms from this culture were incubated in the presence of the mutagen n-methyl-n'-nitro-n-nitrosoguandine in order to obtain a streptomycin dependent mutant. a live vaccine was prepared from this mutant, and healthy pasteurella-free rabbits were vaccinated either by intranasal or subcutaneous administration. either method provided complete protection against homologous, wild ...	1980	7431850
a unique outbreak of pasteurella multocida in a chronic disease hospital.	an outbreak of pasteurella multocida infection, involving seven patients on two adjacent wards, has been observed. all seven patients were debilitated and had underlying chronic neuromuscular and/or pulmonary disease and had a tracheostomy tube in situ. the isolates of p. multocida were of the same biotype and serotype, and had an identical antibiogram. epidemiological studies failed to determine the source of these infections.	1980	7425189
pasteurella multocida arthritis. case report.		1980	7430213
wounds of the hand contaminated by human or animal saliva.	a prospective and retrospective evaluation of 75 patients with hand wounds contaminated by human saliva (35) or animal saliva (40) demonstrates that a program of outpatient management can be sufficient for optimal care in many patients. this series challenges the proposition that hospitalization, radiographs, and surgical debridement are necessary for most such wounds. sixty-seven per cent did not have surgical intervention and no complications resulted. ninety-two per cent received antibiotics. ...	1980	7365851
bacterial peritonitis and bacteremia associated with pasteurella multocida.		1980	7394617
control of fowl cholera in hungary.	experiences of the control of fowl cholera in large poultry farms in hungary are reported. a vaccination method combined with sulfaquinoxaline treatment was developed against fowl cholera. studies were carried out for the determination of the therapeutic and toxic doses of sulfaquinoxaline in fowls experimetnally infected with pasteurella multocida. field experiences with sukvin, a sulfaquinoxaline containing vaccine, against this disease are reported. sukvin was produced by phylaxia serum state ...	1980	7403000
antipyresis: its effect on mortality rate of bacterially infected rabbits.	the effect of an antipyretic drug administered directly into the preoptic-anterior hypothalamus was measured in order to investigate the role of fever on mortality of bacterially infected mammals. new zealand white rabbits (oryctolagus cuniculus) were injected intravenously with pasteurella multocida and either sodium salicylate or a control solution was infused directly into the preoptic-anterior hypothalamus. both groups developed fevers, but the fever of the rabbits infused with the antipyret ...	1980	7363103
[pasteurella multocida endocarditis].		1980	7433073
effect of various feed additives on immune response of turkeys vaccinated with live pasteurella multocida in drinking water.	various feed additives were included in diets of young turkeys being administered live pasteurella multocida, clemson university (cu) strain, in drinking water. erythromycin, neomycin, and oleandomycin reduced immune response the most. most medications that are not effective against p. multocida can be included in turkey feed during cu vaccination.	1980	7436965
pasteurella multocida meningitis.	pasteurella multocida appears to be a very rare cause of meningitis. the bacterium has morphological similarities with other causative organisms, particularly haemophilus influenzae, and its apparent rarity may be due partly to misidentification. this case, only the fourth reported from the united kingdom, could not be distinuished clinically from the meningitis, owing to other pyogenic bacteria.	1980	7433325
pathology of experimental avian cholera in mallard ducks.	mallard ducks (anus platyrynchos) challenged with two isolates of pasteurella multocida developed either acute or chronic lesions, depending on the isolate of p. multocida and the inoculation dose. ducks that died acutely of avian cholera had lesions of a hemorrhagic septicemia with widespread vascular damage and focal necrosis in liver, spleen and other organs. ducks that survived challenge developed chronic lesions in a variety of organs, including brain, lung, air sacs, joints, and eyes. some ...	1980	7436961
pasteurella multocida: antibody-mediated resistance to virulent challenge exposure in vaccinated turkeys.	aspects of antibody-mediated resistance to pasteurella multocida infection in vaccinated turkeys were investigated. pasteurella immune serum obtained from vaccinated turkeys was shown to confer temporary protection to nonvaccinated turkey poults. recipients given immune serum were free of clinical signs of disease for at least 8 days after im challenge exposure with virulent p multocidae 1059. all turkeys given normal serum died within 36 hours of challenge exposure. vaccinated bursectomized tur ...	1980	7447124
vaccination against atrophic rhinitis in swine with a combined bordetella bronchiseptica, pasteurella multocida vaccine.		1980	7467988
preliminary clinical pharmacological investigations of tylosin and tiamulin in chickens.	summary the minimal inhibitory concentrations (m1c) of tiamulin and tylosin for mycoplasma. gram-positive, and gram-negative micro-organisms isolated from chickens were determinated by the agar dilution method. median m1c values for tiamulin against mycoplasma gallisepticum (0.05 µg/ml) and mycoplasma synoviae (0.10 µg/ml) were 2 to 4 times lower than the corresponding values for tylosin. tiamulin was also slightly more effective in vitro in inhibiting escherichia coli, pasteurella multocida, ...	1980	22039981
epithelial papilloma and squamous cell carcinoma of the nasal cavity and paranasal sinuses: a clinicopathological study.	seventeen cases of intranasal epithelial tumors are reviewed. thirteen were epithelial papillomas and four were squamous cell carcinomas associated with epithelial papillomas. in two cases followed over a 10 year period, transformation from an initial papilloma into a carcinoma was demonstrated. the histopathologic caracteristics of these lesions are described including the presence of prominent palisading and intraepithelial nesting in some tumors. the literature was reviewed for reports of car ...	1980	1000480
[the sensitivity of clinical indices for periodontal studies].	some of the clinical indices that are most frequently used in periodontal examinations were tested for sensibility. when chosen with regard to the objective of the respective examinations, they are a great help in evaluating gingival changes. their shortcomings become manifest especially when compared with objective data (po2, ph, resistance, volume pulse, responsiveness tests). the requirements that should be met under these conditions are formulated.	1980	273323
[case of von recklinghausen disease with bullous lung cyst and large cell carcinoma].		1980	1320090
tissue culturing of malignant melanomas in the presence of cytotoxic agents.		1981	274007
joubert syndrome. respiratory failure requiring home mechanical ventilation.	a case of joubert's syndrome with respiratory insufficiency requiring mechanical ventilatory support is presented. the case illustrates the complex clinical, ethical and technical aspects in the management of patients with this syndrome and the feasibility of extending mechanical ventilatory support to the home setting. a caring, knowledgeable care team and a loving supportive family are required to properly continue treatment in the home in cases of this rare syndrome.	1981	1789891
the pebbled path (sequel to the rocky road).		1981	273832
prevention--the only realistic hope.		1981	273809
[experimental chemotherapy of onchocerciasis].		1981	351761
start early to engineer against noise.		1981	181712
pasteurella multocida empyema: case report and review of the literature.	a case report and review of 13 cases of pasteurella multocida empyema in the english literature demonstrate the apparent increased pathogenicity of this organism in patients with chronic lung disease. the infections were marked by their indolence, minimal febrility, blood-tinged pleural fluid, and predilection for the elderly. the was no characteristic roentgenographic pattern. animal exposure commonly preceded the illnesses. it is postulated that the disease occurs in patients with impaired pul ...	1981	7468640
pasteurella multocida infection in the hand.	we have discussed 13 patients with pasteurella multocida infection of the hand, six of whom developed chronic hand impairment as a result of the infection. it is thus apparent that chronic morbidity following pasteurella infection of the hand is nearly 50 percent. despite a fairly wide antibiotic susceptibility pattern of this organism, the infection may have long-term consequences such as osteomyelitis, or small joint stiffness due to paraarticular infection. we wish to emphasize the rapid evol ...	1981	7443859
[streptomycin-dependent mutants of a pasteurella multocida strain isolated from poultry].	a culture of strain pasteurella multocida 115, isolated from a hen affected with fowl cholera, was treated with 50 mcg/cm3 streptomycin and subjected to selection at an additional treatment with 200 mcg/cm3 of the same antibiotic. a total of 16 streptomycin-resistant mutant strains were obtained. all of them were shown to be avirulent in testing their pathogenicity for mice, however, two of the mutants were of lowered virulence in tests with birds. fourteen days post vaccination birds that survi ...	1981	7331223
fowl cholera found in imported myna birds (eulabes intermedia).	of 480 myna birds imported from thailand in 1976, 54 birds died shortly after arrival in japan. bacteriological and pathological examination were carried out on seven of them. pasteurella multocida was almost purely isolated from all the liver, heart, spleen and trachea examined. somatic antigen of the isolants was o-5 of namioka and murata. dissection revealed hyperemia of the trachea, edema of the lungs, increase of pleural fluid, and petechial or ecchymotic hemorrhages in the liver, heart and ...	1981	7335123
[characterization of structural elements in lipopolysaccharides of pasteurella multocida].	in the main fraction of oligosaccharides obtained after the acetic acid hydrolysis of the lipopolysaccharides of the strain pm were identified: terminal bound glucose and l-glycero-d-manno-heptose, 1,2-,1,3,4-, and 1,3,4,6,-linked heptose. the oligosaccharide of the strain 1297 s contains terminal linked galactose, 1,4- or 1,6-linked glucose and 1,4-linked n-acetylglucosamine additionally. the molar ratios of these elements show the heterogenicity of the preparations. the determined molecular we ...	1981	7324510
[utilization of l-aspartate, l-malate and fumarate by pasteurella multocida].	strains of pasteurella multocida use l-aspartate, l-malate and furmarate, respectively, as substrates for production of succinic acid which accumulates in the medium. as was established by studies with 14c and 3h labelled substrates, the degradation of these substances proceeds analogous via the citric acid cycle.	1981	7336769
a modified barrier system for maintenance of pasteurella-free rabbits.	a modified barrier system for maintaining pasteurella multocida-free rabbits in an animal facility also housing pasteurella multocida-infected rabbits was implemented. all research and laboratory animal technical personnel performed their duties involving non-infected rabbits prior to working with infected rabbits housed in separate rooms of the facility. bacterial culture data involving mature rabbits indicated a 17% infection rate when pasteurella-free rabbits were housed in a conventional man ...	1981	7341860
immunoelectrophoresis employing avian antisera for the detection and quantitation of pasteurella multocida antigens.	immunoelectrophoresis with various buffer systems at high and low ph was examined for suitability to detect and quantitate pasteurella multocida antigens with turkey or chicken anti-p. multocida sera. counterimmunoelectrophoresis was used to develop a buffer system for one-dimensional, two-dimensional, and rocket immunoelectrophoresis. the effects of ph, buffer, and molarity on resolution of immunoprecipitates were determined; 0.05 m sodium acetate-acetic acid buffer at ph 5.6 was the most suita ...	1981	7264316
effects of nitric oxide on resistance to bacterial infection in mice.	continuous exposure to 2 ppm nitric oxide (no) for as long as 4 wk did not reduce the resistance of male mice to infection by aerosol inoculation with pasteurella multocida. in contrast, mortality was slightly enhanced and survival shortened in no-exposed compared to control female mice; however, the importance of these small differences is uncertain. these results suggest only that male and female mice did not react similarly to the infectious challenge after exposure to no.	1981	7265314
selective media for pasteurella multocida and bordetella bronchiseptica.	easily prepared and inexpensive culture medium for the isolation of pasteurella multocida and bordetella bronchiseptica from the nares of laboratory rabbits was prepared by incorporating 2 micrograms/ml clindamycin into standard blood agar. using this medium, the time and materials required to identify and isolate pasteurella multocida was substantially reduced with only a slight loss in sensitivity. the combination of 2 micrograms/ml clindamycin and 4 micrograms/ml neomycin was effective in iso ...	1981	7253549
characteristics and biotypes of pasteurella multocida isolated from humans.	fifty-two isolates of pasteurella (48 strains of pasteurella multocida and 4 strains of atypical pasteurella) were identified by conventional and commercial test systems. all strains fermented glucose, sucrose, and fructose in purple broth base (difco laboratories) with bromocresol purple as indicator, although the atypical pasteurella produced fermentation reactions that were barely perceptible. eleven different biotypes were identified by fermentation reactions in maltose, mannitol, xylose, so ...	1981	7240390
ventilatory failure after pasteurella multocida pneumonia.		1981	7336378
gross and microscopic lesions of middle and inner ear infections in swine.	in all infected middle ears from 36 swine, there was purulent material in the tympanic cavity and tympanic bulla. frequently, there were lysis of the tympanic membrane and ossicles and purulent material in the external ear canal. sometimes, there were desquamation of the stratified squamous epithelium lining the tympanic cavity, and osteolysis of the underlying osseous wall with subsequent fibrosis. in those swine with inner ear infections, there were infiltration of neutrophils and fibrin in th ...	1981	7294480
characteristics of 20 human pasteurella isolates from animal bite wounds.	the bacteriological characteristics of 18 isolates of pasteurella multocida and two isolates of pasteurella pneumotropica from infected animal bite wounds have been studied. a high proportion (8/18) of the p. multocida isolates fermented lactose and five fermented maltose. two failed to ferment sorbitol. neither of the p. pneumotropica strains showed ornithine decarboxylase activity. other biochemical characteristics were mainly in agreement with previous reports. the susceptibility of the isola ...	1981	7315339