Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| detection of helicobacter pylori from endoscopic biopsies and the biochemical characteristics of these isolates. | helicobacter pylori (formerly campylobacter pylori) has been recently described as a gastritis-associated bacterium. we examined endoscopic biopsies of 100 patients with dyspepsia and found h. pylori in the gastric antrum of 34 (34%) by either culture, urease tests and/or histology. thirty-one out of 41 patients (75.6%) confirmed to have chronic active gastritis histologically had h. pylori in their gastric antrum compared to 3 out of 59 patients (5.1%) with dyspepsia but normal histology (p les ... | 1990 | 2102969 |
| campylobacter pylori infection: experience in a multiracial population. | over a 15-month period, 399 patients with dyspepsia were investigated for the presence of campylobacter pylori infection. half of the patients (50.6%) had campylobacter organisms in the antrum of the stomach. c. pylori was found in 96.1% of patients with histological changes of chronic active gastritis in the antrum. of patients with duodenal and gastric ulcers, 87.8% and 87.5%, respectively, had campylobacter organisms, as did 39.3% of patients with non-ulcer dyspepsia. c. pylori infection was ... | 1990 | 2103410 |
| histological identification of helicobacter pylori in early and advanced gastric cancer. | 1990 | 2103734 | |
| gastric histology and plasma gastrin response to a meal in patients with duodenal ulcer disease after five years treatment with ranitidine. | fifty asymptomatic patients with duodenal ulcer disease, aged 31-82 years, who had received ranitidine maintenance therapy continuously for five or more years without a symptomatic recurrence, were studied. fasting plasma gastrin concentrations were normal (mean 24 pmol/l, s.d. +/- 22) while the post-prandial gastrin response was variable with maximum plasma concentrations ranging from 16 to 309 pmol/l. endoscopy revealed six asymptomatic peptic ulcers. histological examination of gastric biopsi ... | 1990 | 2103756 |
| dosage of colloidal bismuth subcitrate in duodenal ulcer healing and clearance of campylobacter pylori. | sixty consecutive patients with endoscopically proven duodenal ulcers were given colloidal bismuth subcitrate tablets either as 120 mg q.d.s. or 240 mg b.d., in a randomized single-blind study. the efficacy of each regimen was determined by endoscopic examination and antral biopsy at 4 weeks; if the ulcer remained unhealed, treatment was continued and endoscopy repeated at 8 weeks. the ulcer-healing efficacy of the two regimens was identical; however, in the four times daily group only 27% remai ... | 1990 | 2104073 |
| the interaction between helicobacter pylori culture filtrate and indomethacin: effects on the integrity of human gastric antral mucosa and its prostaglandin e2 production in vitro. | histopathological methods and radioimmunoassay were used to assess the microstructure and prostaglandin e2 production by paired specimens of human gastric antral mucosa; the specimens were studied after 48 h of incubation in base-line tissue culture medium, helicobacter pylori culture filtrate, h. pylori culture control fluid, indomethacin, and h. pylori culture filtrate plus indomethacin. when applied alone, the filtrate did not affect the structure of the mucosal tissue or its prostaglandin e2 ... | 1990 | 2104089 |
| [campylobacter (helicobacter) pylori-induced cost effectiveness-risk considerations]. | 1990 | 2107370 | |
| helicobacter pylori in gastroduodenal disease. | helicobacter pylori is a recently described gram-negative micro-organism, which plays an important role in the pathogenesis of peptic ulcer disease and gastritis. in this paper an outline is given of the history and the pathophysiology of helicobacter pylori, as well as the therapeutic studies aimed at eradication of the bacterium in various clinical entities. | 1990 | 2110652 |
| unsaturated fatty acids and viability of helicobacter (campylobacter) pylori. | helicobacter (campylobacter) pylori was found to be sensitive to the toxic effects of an unsaturated fatty acid (arachidonic acid). data are presented that support the hypothesis that exogenous catalase added to basal media enhances the growth of h. pylori by preventing the formation of toxic peroxidation products from long-chain unsaturated fatty acids. | 1990 | 2112559 |
| hydrophobic characterisation of helicobacter (campylobacter) pylori. | cell-surface hydrophobicity of helicobacter (formerly campylobacter) pylori was tested by aqueous two-phase partitioning and hydrophobic interaction chromatography. the hydrophobicity of h. pylori greatly exceeded that of campylobacter fetus subsp. fetus, c. jejuni and bacillus subtilis. a partition coefficient (pc) of hydrophobicity in the two-phase system was determined for h. pylori. pc was dependent on ph and the pc value was increased by greater than 20-fold at ph 2.5. lithium cations incre ... | 1990 | 2113100 |
| the 14co2 urea breath test for helicobacter pylori infection. | 1990 | 2118567 | |
| association of helicobacter pylori with acid peptic disease in karachi. | the prevalence of h. pylori infection in 200 dyspeptic patients undergoing upper g.i. endoscopy was investigated by histology and rapid urease test. h. pylori was associated with 86% cases of chronic gastritis, 84.6% cases of duodenal ulcers and 78.5% of gastric ulcers. none of the 15 histologically normal gastric biopsies showed h. pylori. | 1990 | 2123260 |
| helicobacter pylori induces lymphocyte activation in peripheral blood cultures. | helicobacter pylori-induced in vitro stimulation of mononuclear cells was characterized by measuring dna synthesis response, interferon-gamma (ifn-gamma) secretion and the number of immunoglobulin-secreting cells. the strength of these responses was measured in 51 subjects comprising 36 dyspeptic patients from the gastroenterological unit and 15 members of the laboratory staff. nineteen subjects had antibodies to h. pylori and 32 did not. the responses were compared with respect to h. pylori ant ... | 1990 | 2124957 |
| validation of a simplified carbon-14-urea breath test for routine use for detecting helicobacter [correction of heliobacter] pylori noninvasively. | a carbon-14 (14c) urea breath test for detecting helicobacter pylori with multiple breath sampling was developed. carbon-14-urea (110 kbq) administered orally to 18 normal subjects and to 82 patients with helicobacter infection. the exhaled 14c-labeled co2 was trapped at 10-min intervals for 90 min. the total 14c activity exhaled over 90 min was integrated and expressed in %activity of the total dose given. in normals, a mean of 0.59% +/- 0.24% was measured, resulting in an upper limit of normal ... | 1990 | 2125066 |
| a placebo controlled trial of bismuth salicylate in helicobacter pylori associated gastritis. | in a placebo controlled prospective clinical trial of bismuth salicylate in helicobacter pylori associated gastritis, 52 adult patients were randomly allocated to treatment with bismuth salicylate or placebo. helicobacter pylori were totally cleared in 77% patients in bismuth group but none in placebo group (p less than 0.001). resolution of gastritis (p less than 0.001) and improvement of symptoms (p less than 0.01) were significantly better in patients where h. pylori infection cleared as comp ... | 1990 | 2125658 |
| helicobacter pylori associated chronic gastritis and peptic ulceration in patients taking non-steroidal anti-inflammatory drugs. | helicobacter pylori is now recognized as a frequent cause of histological chronic gastritis, and this has radically changed our understanding of this common condition. in the light of these developments, the traditional view that non-steroidal anti-inflammatory drugs are one of the common 'environmental' causes of chronic gastritis has been re-examined. gastric mucosal biopsies have been studied from 430 patients undergoing routine upper gastrointestinal endoscopy, 99 of whom had recently been t ... | 1990 | 2129639 |
| helicobacter pylori infection treated with a tripotassium dicitrato bismuthate and metronidazole combination. | seventy-two patients with h. pylori infection in their antral mucosa took part in the study. forty-three received metronidazole 400 mg t.d.s. for two weeks, plus de-nol tabs 2 b.d. for four weeks, and the remaining 29 patients received metronidazole 400 mg t.d.s. for two weeks plus de-nol liquid 5 ml q.d.s. for four weeks. seven of 57 h. pylori isolates were found to have pre-treatment metronidazole resistance. success, in terms of eradication of h. pylori, was assessed using a one-month post-tr ... | 1990 | 2129652 |
| morphological study of the gastric antral mucosa colonized by campylobacter pylori. | antral biopsies from 56 patients who underwent gastroscopy for upper gastrointestinal symptoms were studied by transmission electron microscopy. campylobacter pylori was demonstrated in specimens from 39 patients. the bacteria were present in 3 of the 8 normal specimens and in 36 of the 48 cases with chronic gastritis. electron microscopy showed that organisms were located deep the mucous layer in intimate relation with the luminar surface of the antral epithelium. no ultra-structural evidence w ... | 1990 | 2131923 |
| helicobacter pylori and chronic antral erosions: our experience. | 1990 | 2131932 | |
| the influence of high blood levels of urea on the presence of campylobacter pylori in the stomach: a clinical study. | in order to determine whether urea influences the presence of campylobacter pylori (cp) in the stomach, the incidence of this infection was determined in patients with chronic renal failure who received no treatment (group a) or underwent regular hemodialysis (group b). a third group was examined as control. biopsies from the gastric antrum were taken for histological investigation and for cp detection. no significant differences among the 3 groups of patients were found with regards to the inci ... | 1990 | 2131933 |
| the first cases of helicobacter pylori (campylobacter pylori) reported from costa rica. | two gastric antrum biopsies of each of 92 consecutive patients undergoing gastroendoscopy were studied. the first biopsy was cultured for helicobacter (campylobacter) pylori. the second specimen was fixed and processed for histopathological analysis. the bacteria were isolated from 34 (81%) of 42 patients with nonspecific chronic gastritis, 19 (90%) of 21 cases of duodenal or gastric peptic ulcer, and from 3 (23%) of 13 normal patients. the overall frequency of isolation was 62 (67%) of the 92 c ... | 1990 | 2134727 |
| [histopathologic changes associated with the presence of helicobacter pylori in antral mucosa]. | helicobacter pylori is a gram negative bacteria which has recently been associated to tissular changes of the upper digestive tract, however, the causal role has not yet been determined. of 150 patients studied, 63 had tissular changes associated to helicobacter pylori (hp), 8 had hp without tissular related changes (of whom 3 suffered bulbar ulcus and 1 gastric ulcus); the rest of the patients had hiatus hernia associated to distal esophagitis or pyloric stenosis; and only one patient was found ... | 1990 | 2135572 |
| [clinical significance of helicobacter pylori]. | 1990 | 2135580 | |
| [can epigastric pain and non-ulcerative dyspepsia in children and adolescents be campylobacter pylori infection?]. | the authors examined 263 children and adolescents aged 5-20 years who suffered from so-called non-ulcerative dyspepsia or epigastric pain, because of the suspected presence of campylobacter pylori. in 31.9% of the examined subjects direct microbiological methods revealed its presence in the gastroduodenal mucosa. the confidence limit of positive results of campylobacter pylori in the population is between 27.58% and 38.84%, the probability being 95%. the authors proved a mutual correlation betwe ... | 1990 | 2136426 |
| [cytotoxic changes in cell cultures induced by newly isolated strains of campylobacter pylori]. | suspensions of primocultures of two strains of camplyobacter pylori, isolated from bioptic materials collected from patients with nodular hyperplasia of the pyloric antrum and with gastric ulcers were inoculated to 20-hour confluent or almost confluent cell cultures line vero, mccoy and ma 104 in test tubes and petri dishes. both strains of c. pylori adhered markedly to cell lines vero and mccoy and after 72 hours led to marked morphological changes of the cells. the changes were characterized i ... | 1990 | 2136427 |
| [determination of antibodies to campylobacter pylori in children and adolescents with gastroduodenal disorders]. | serological examination of antibodies against campylobacter pylori was made in 195 boys and girls aged 9-20 years. in all on account of gastrointestinal complaints endoscopy was indicated. the results of microbiological and histological finding), in particular in the antrum and corpus of the stomach). positive titres antrum and body of the stomach were compared with results of the complement fixation test and the elisa reaction. antibodies against c. pylori were detected in 64 of the examined su ... | 1990 | 2136428 |
| [campylobacter pylori--relation to gastric pathology and the effect of bismuth therapy]. | twenty-four patients with symptoms of gastric dyspepsia and active chronic gastritis in the antral mucosa were examined for the presence of campylobacter pylori before and after treatment with bismuth salts (12 patients) and antacids (12 patients). bismuth, contrary to the used antacid, significantly reduced the finding of c. pylori in the antral mucosa and had a favourable effect on the active form of chronic antral gastritis. | 1990 | 2136429 |
| [morphologic changes in chronic active superficial campylobacter pylori-positive antrum gastritis after treatment with bismuth]. | the authors investigated the effect of one month bismuth treatment (bismuthi citrici 120 mg per capsule), 4 x 120 mg/day, on morphological changes of the gastric mucosa along with the effect on campylobacter pylori (cp) in a group of 23 probands with histologically verified active superficial cp positive antrum gastritis. the probands suffered only from functional dyspepsia, to eliminate the action of other disease of the digestive tract on chronic gastritis. complete eradication of cp occurred ... | 1990 | 2136460 |
| [physiopathological basis for the treatment of peptic ulcer]. | peptic ulcer pathophysiology has advanced in several ways during the last years; the following facts has been put forward: a) there has been recognized specific receptors controlling oxyntic cell secretion for histamine, acetylcholine, gastrin and prostaglandins. agonists and antagonists for the above mentioned receptors has been synthesized. the physiology of the proton-pump located at the luminal side of the mucous membrane has been clarified. this pump is responsible for hcl secretion and can ... | 1990 | 2152274 |
| [the igg antibody response in patients colonized by helicobacter pylori]. | the igg antibody response specific to helicobacter pylori was evaluated through elisa in a group of 92 gastric patients colonized by this bacteria. 74 had gastritis and 19 gastroduodenal ulcer. three control groups were studied in a similar way: normal adult volunteers (n = 17), adults with e coli or s typhi bacteremia (n = 30) and normal infants (n = 30). igg antibody response to h pylori was demonstrated in 98% of colonized patients and 0% of infants. asymptomatic individuals and those with ba ... | 1990 | 2152642 |
| failure of azythromycin to eradicate campylobacter pylori from the stomach because of acquired resistance during treatment. | 1990 | 2153337 | |
| typing of campylobacter pylori by bacterial dna restriction endonuclease analysis and determination of plasmid profile. | campylobacter pylori isolates from 37 symptomatic patients and 3 asymptomatic volunteers were examined by chromosomal dna restriction endonuclease analysis and determination of plasmid profile. restriction digests with hindiii, haeiii, pvuii, and bglii produced clear and reproducible results that permitted discrimination between different strains. only 35% of c. pylori isolates were found to have plasmid dna. isolates from different patients, including those from two pairs of siblings, had uniqu ... | 1990 | 2153701 |
| is herpes simplex virus associated with peptic ulcer disease? | to test the hypothesis that herpes simplex virus type 1 (hsv-1) may be associated with peptic ulcer disease, we examined ulcerative lesions of the distal stomach and proximal duodenum for the presence of nucleic acids and antibodies specific for hsv-1. utilizing in situ hybridization, immunocytochemistry, and polymerase chain reaction with sequencing, gastric or duodenal tissues from 4 of 22 patients (18%) with documented peptic ulcer disease demonstrated the presence of both specific hsv-1 nucl ... | 1990 | 2157877 |
| increased tight junction width in two children with ménétrier's disease. | protein-losing enteropathy (ple) and edema are usually the most prominent clinical features in children with ménétrier's disease. however, the changes in gastrointestinal mucosa that can cause ple have not been described yet in children. we studied by electron microscopy the mucosa of the gastric fundus, which is the site where macroscopic changes are most prominent, in two children with ménétrier's disease. we found that tight junction width was increased to 10.5 +/- 0.94 nm (mean +/- 1 sd) in ... | 1990 | 2167358 |
| signature patterns of dna restriction fragments of helicobacter pylori before and after treatment. | the genomic dna of helicobacter pylori was studied by electrophoretic analysis of restriction endonuclease fragments. twenty seven isolates from eight patients in the united kingdom, obtained before and after treatment with nitrofurantoin, and two reference strains from australia and peru were investigated. digestion of dna with haeiii, which gave the clearest band pattern of the 20 enzymes tested, showed that each set of isolates from a single patient had a unique band pattern. the dna signatur ... | 1990 | 2169483 |
| possible role of leukotrienes in gastritis associated with campylobacter pylori. | this study was done to evaluate the role of leukotrienes (lts) in gastritis associated with campylobacter pylori. biopsy specimens of gastric mucosa were obtained endoscopically from 18 patients with nonulcer dyspepsia for bacteriological and histological examination and extraction of lts. there was correlation between the ltb4 level in the mucosa and the degree of gastritis evaluated histologically. the level was higher when infiltration of neutrophils in the gastric mucosa was more extensive. ... | 1990 | 2170499 |
| comparison of anti-helicobacter (campylobacter) pylori igg antibodies between different areas of belgium. | we have collected sera from 4053 patients of different parts of belgium. sera were randomly selected whatever the kind of pathology. anti-helicobacter (campylobacter) pylori igg were determined with an elisa technique using whole formalized bacteria. the results suggest that the mean antibody titres differ between various areas, with an overall higher prevalence in the north-western part of the country. | 1990 | 2173316 |
| drug therapy for helicobacter pylori infection: problems and pitfalls. | antibacterial chemotherapy against helicobacter pylori is currently being assessed by open or randomized controlled clinical studies for its efficacy in eradicating this bacterium from the stomach of patients with gastritis or gastroduodenal ulcer. whereas there is presently no "optimal" agent and treatment scheme, the combination of some antibiotics (metronidazole, tinidazole, amoxicillin) with bismuth salts proves definitely superior in vivo to either of these agents administered alone. severa ... | 1990 | 2174642 |
| comparison of different tests for helicobacter pylori. | 1990 | 2178404 | |
| helicobacter pylori: controversies and an approach to management. | helicobacter pylori (formerly, campylobacter pylori) is a gram-negative, spiral-shaped bacterium with a strong affinity for gastric-type epithelium. convincing evidence indicates that h. pylori plays an etiologic role in the development of chronic, nonspecific gastritis, and it may play an important role in the pathogenesis of duodenal ulcer disease. an etiologic role for this organism in chronic gastric ulceration, nonulcer dyspepsia, and gastric carcinoma is not established. whereas the diagno ... | 1990 | 2179647 |
| rapid urease tests for campylobacter pylori. | 1990 | 2180988 | |
| helicobacter pylori and the pathogenesis of gastroduodenal inflammation. | helicobacter pylori is a newly discovered gram-negative bacterium that lives in the human stomach and duodenum. infection with this organism is strongly associated with type b antral gastritis and with peptic ulcer disease. recent evidence from human volunteer studies, therapeutic trials with antimicrobial agents, and experiments with animal models indicates that h. pylori plays an etiologic role in the pathogenesis of type b gastritis. gastric metaplasia is observed in virtually all patients wi ... | 1990 | 2181029 |
| identification of campylobacter pylori in gastric biopsy smears. | the use of gastric biopsy imprint smears to diagnose campylobacter pylori was compared with the use of tissue sections and cultures. multiple gastric biopsies were taken from the mucosa of 42 patients during endoscopy. imprint smears were prepared from the samples used to make tissue sections; other samples were used for microbiologic culture. there was a good concordance (93%) between the morphologic diagnosis of c pylori in the air-dried, giemsa-stained smears and the tissue sections; the cyto ... | 1990 | 2181802 |
| evaluation of a selective enrichment technique for the isolation of campylobacter pylori. | to cultivate campylobacter pylori from contaminated biopsy specimens, brucella broth was supplemented with 10% fetal calf serum, 1% vitox, 1000 units/ml polymyxin b sulfate, 10 micrograms/ml vancomycin, and 2 micrograms/ml amphotericin b. pseudomonas aeruginosa, candida albicans, and enterococcus fecalis were cocultivated with c. pylori. all four strains of c. pylori were recoverable at 24 h. when 21 c. pylori strains were studied in pure culture, 86% grew in the selective enrichment medium. in ... | 1990 | 2182378 |
| campylobacter pylori: a new pathogen. | there is now considerable evidence suggesting that c. pylori is a human pathogen. the strong association between c. pylori and gastroduodenal disease is well documented. a number of hypotheses have been suggested for the pathogenic mechanisms of c. pylori-induced gastroduodenal disease, including the production of cytotoxins and the mechanical disruption of the epithelium. at the present time, treatment with a combination of antimicrobial agents eradicates the infection in approximately 50% of c ... | 1990 | 2183821 |
| campylobacter pylori and its role in peptic ulcer disease. | in almost all patients with genuine nondrug-induced duodenal or gastric ulcer there is evidence of gastric campylobacter pylori colonization and concomitant inflammation. c. pylori is only demonstrable in the duodenal cap when there is "gastric mucus metaplasia." suppression or eradication of c. pylori with antibiotic therapy may accelerate duodenal ulcer healing. the relapse rate of duodenal ulcer is less after temporary clearing or permanent eradication of c. pylori. as eradication of c. pylor ... | 1990 | 2184128 |
| [campylobacter pylori-helicobacter pylori. a long development]. | 1990 | 2184426 | |
| campylobacter (helicobacter) pylori. is peptic disease a bacterial infection? | 1990 | 2184791 | |
| purification and characterization of urease from helicobacter pylori. | urease was purified 112-fold to homogeneity from the microaerophilic human gastric bacterium, helicobacter pylori. the urease isolation procedure included a water extraction step, size exclusion chromatography, and anion exchange chromatography. the purified enzyme exhibited a km of 0.3 +/- 0.1 mm and a vmax of 1,100 +/- 200 mumols of urea hydrolyzed/min/mg of protein at 22 degrees c in 31 mm tris-hcl, ph 8.0. the isoelectric point was 5.99 +/- 0.03. molecular mass estimated for the native enzym ... | 1990 | 2188975 |
| [campylobacter pylori and its role in the etiopathogenesis of upper digestive tract diseases]. | 1990 | 2192401 | |
| [helicobacter pylori and gastric pathology]. | 1990 | 2193600 | |
| [does helicobacter pylori have a direct proteolytic effect in ulcerative disease?]. | helicobacter pylori (h.p.), has been shown, experimentally, to exert a proteolytic activity against mucous fractions. aim of this study was to assess the prevalence of h.p. in peptic ulcer and to analyze its possible influence on gastric mucus components, on peptic activity in gastric juice and the possible action on peptic secretion. 223 patients undergoing upper gastrointestinal endoscopy were analyzed for the presence of h.p. in the mucosa: 99 duodenal ulcer patients (d.u.), 58 gastric ulcer ... | 1990 | 2194877 |
| gastritis in the elderly. | the elderly have an increased prevalence of gastritis and the complications associated with it. the two major classes of acute and chronic gastritis, type a and b, are discussed as they relate to clinical findings, histologic features, and pathogenesis. an age-related increase in the frequency of helicobacter pylori (formerly campylobacter pylori) infection in the elderly parallels the known age-related increase in the prevalence of gastritis. the close association between gastritis in the elder ... | 1990 | 2194946 |
| helicobacter pylori (formerly campylobacter pyloridis/pylori) 1986-1989: a review. | 1990 | 2196282 | |
| a simple method to detect helicobacter pylori in gastric specimens. | 1990 | 2196955 | |
| bismuth therapy in gastrointestinal diseases. | bismuth therapy has shown efficacy against two major gastrointestinal disorders: peptic ulcer disease and diarrhea. in peptic ulcer disease it is as effective as the h2-receptor antagonists, costs considerably less, and offers a lower rate of relapse. when helicobacter pylori is implicated, bismuth acts as an antimicrobial agent, suppressing the organism but not eliminating it. in recent studies, bismuth compounds have been used with conventional antibiotics, producing elimination of the organis ... | 1990 | 2199292 |
| campylobacter pylori. a new era in gastroduodenal disorders? | 1990 | 2199425 | |
| immunocytochemical detection of helicobacter pylori in formalin fixed tissue biopsy specimens. | 1990 | 2199535 | |
| survival of helicobacter pylori in water and saline. | 1990 | 2199542 | |
| identification of campylobacter pylori by gastric brush cytology. | 1990 | 2201508 | |
| helicobacter pylori: bridging the credibility gap. | in summary, therefore, there are interesting associations between h pylori, duodenal ulcer, and non-ulcer dyspepsia. in type b gastritis there may be enough evidence to suggest a causal role. the relation between gastritis and upper gastrointestinal symptomatology, however, remains contentious. the relation between h pylori and acid secretion may be more intimate than was previously thought. 'pylorites' must temper their enthusiasm and provide hard data; 'schwartzians' must broaden their horizon ... | 1990 | 2201586 |
| helicobacter (= campylobacter) pylori in africa. | epigastric pain is a common complaint throughout africa, mostly in the form of non-ulcer dyspepsia. it has recently been suggested that helicobacter (= campylobacter) pylori, a bacterium that colonizes the gastric mucosa and causes type b gastritis, may be the cause of this epigastric pain. this paper reports the endoscopic, histological and bacteriological findings in 57 patients presenting with epigastric pain to the university of maiduguri teaching hospital during one year, together with a re ... | 1990 | 2202107 |
| effects of sucralfate and sulglycotide treatment on active gastritis and helicobacter pylori colonization of the gastric mucosa in non-ulcer dyspepsia patients. | we conducted a double-blind randomized treatment study on patients affects by non-ulcer dyspepsia in whom multiple biopsy specimens showed active gastritis. patients were given either 3 g/day of sucralfate (n = 39) or 600 mg/day of sulglycotide (n = 50) for 6 wk, a glycopeptide isolated from pig duodenum constituents. endoscopy was carried out at baseline and at the end of treatment. we took biopsies from the gastric body (twice) and antrum (six times) at each endoscopy in order to determine gra ... | 1990 | 2202200 |
| [efficacy of a bismuth combination preparation. efficacy in the treatment of chronic active gastritis and non-ulcerous dyspepsia]. | in an open, randomized controlled study, the effect of a combined bismuth preparation, bismuth nitrate and bismuth aluminate on the elimination of helicobacter pylori, inflammatory activity in the gastric mucosa in chronic type b gastritis, and on the patient's symptoms was investigated. included in the study were 36 patients with non-ulcerous dyspepsia and chronic gastritis. twelve patients (group a) received 4 x 1 tablet a day (800 mg total daily dose), 12 patients (group b) 2 x 2 tablets a da ... | 1990 | 2202619 |
| campylobacter pylori in israel: prospective study of prevalence and epidemiology. | antral biopsy samples were taken from 147 patients undergoing gastroscopy. campylobacter pylori was cultivated from 100 of these patients. c. pylori was isolated from 76% of the specimens showing any degree of histologic gastritis, but from only 11% of specimens with completely normal histology. a questionnaire was completed on all patients and included demographic, epidemiologic and clinical information. sephardic origin, smoking, and a bad taste in the mouth were more prevalent in the campylob ... | 1990 | 2205596 |
| the radiologic and endoscopic investigation and etiologic classification of gastritis in children. | in 11 children the endoscopic criteria for gastritis were correlated with radiologic and pathological findings. an etiologic classification is proposed. the diagnoses included gastric involvement by crohn's disease (five children), eosinophilic gastroenteritis (one), diffuse varioliform gastritis (two), erosive gastritis associated with campylobacter pylori infection (two) and idiopathic erosive gastritis (one). eight of the nine double-contrast barium studies and only one of the three single-co ... | 1990 | 2207775 |
| gastrointestinal function and structure in hiv-positive patients. | we examined 19 patients (17 men) with human immunodeficiency virus (hiv) infection and gastrointestinal symptoms to determine whether those symptoms were due to either a gastrointestinal tract infection or a defect in mucosal absorption because of an enteropathy. the erythrocyte folate and serum vitamin b12 levels were within normal limits in all of the patients. the serum ferritin level was elevated in 12. the xylose absorption test results were abnormal in 8 of the 13 patients able to complete ... | 1990 | 2207920 |
| identification of campylobacter pylori by endoscopic brush cytology. | to investigate the value of papanicolaou-stained endoscopic brush samples in the diagnosis of campylobacter pylori infection of the upper gastrointestinal tract, 138 brush and biopsy samples from the esophagus, stomach, and duodenum, taken concomitantly, were reviewed retrospectively. in 35 cases, campylobacter-like organisms (clos) were found in both cytology and biopsy samples. in 15 cases, clos were seen in biopsy material only, and in 8 cases, clos were found in cytology material only. clos ... | 1990 | 2209347 |
| development of a human stomach explant organ culture system to study the pathogenesis of helicobacter pylori. | these studies were undertaken to define conditions under which helicobacter (formerly campylobacter) pylori and viable human gastric mucosa could coexist in tissue culture with the ultimate goal of developing an in vitro experimental model which could be used to study interactions between h. pylori and gastric epithelium. antral gastric biopsies obtained at upper endoscopy were placed in culture in either cmrl-1066 or keratinocyte growth media and incubated at 37 degrees c in either an oxygen-en ... | 1990 | 2210096 |
| a small animal model of human helicobacter pylori active chronic gastritis. | isolation of a spiral-shaped bacterium closely related to helicobacter pylori from the cat stomach made it possible to investigate new small animal models of gastric infection. pure cultures of this bacterium, provisionally named "helicobacter felis," were fed to germ-free mice. the organism colonized the stomach in large numbers in mucus and deep in the gastric pits and showed the same gastric trophism found with h. pylori. significant histopathology was seen in all h. felis-infected mice. at 2 ... | 1990 | 2210240 |
| reduction of gastric ulcer recurrence after suppression of helicobacter pylori by cefixime. | the effect on the recurrence of gastric ulcers after suppression of helicobacter pylori by combined treatment with cimetidine and the antimicrobial drug cefixime was investigated. twenty one of 43 patients with endoscopically proved gastric ulcer and h pylori infection were randomly assigned to receive cimetidine 800 mg daily for 12 weeks; the remaining 22 patients received cimetidine 800 mg daily for 12 weeks plus cefixime 100 mg daily for the last two weeks. after treatment, 88% of 17 patients ... | 1990 | 2210464 |
| adjuvant antibiotic therapy in duodenal ulcers treated with colloidal bismuth subcitrate. | persistence of helicobacter pylori after duodenal ulcer healing is associated with high rates of ulcer relapse. we compared colloidal bismuth subcitrate alone with cbs combined with one of four antibiotic regimens in the treatment of duodenal ulcers. endoscopy and antral biopsies were performed before treatment and four weeks afterwards. biopsy specimens were examined for histological evidence of gastritis and by gram stain and culture for h pylori infection. altogether 141 patients were allocat ... | 1990 | 2210469 |
| geographic association of helicobacter pylori antibody prevalence and gastric cancer mortality in rural china. | to examine the geographic association between helicobacter pylori infection and gastric cancer, we have assessed the prevalence of igg antibodies to h. pylori in plasma samples taken in 1983 from 1882 men, aged 35-64 years, in 46 rural counties of the people's republic of china. the gastric cancer mortality rates in these countries in 1973-75 varied from 3 per 1,000 (cumulative rate, 0-64 years) to 69 per 1,000, while the proportions of the population positive for h. pylori antibodies (based on ... | 1990 | 2210881 |
| serum pepsinogen i and gastrin concentrations in children positive for helicobacter pylori. | serum pepsinogen i, serum gastrin concentration, and inflammatory scores were measured in a population of 71 children undergoing upper gastrointestinal endoscopy for investigation of upper abdominal pain. forty four were initially colonised with helicobacter pylori. the indices were measured before treatment (in 71 children), one month (in 41 children), and six months (in 21 children) after stopping treatment. before treatment there was a significant correlation between serum pepsinogen concentr ... | 1990 | 2212069 |
| the susceptibility of campylobacter pylori to antiulcer agents and antibiotics. | the antibacterial activities of antiulcer agents and antibiotics against campylobacter pylori were studied. the mic90 values of three kinds of antibiotics--macrolides, beta-lactams, and metronidazole--were 0.05-0.78, 0.39-1.56, and 12.5 micrograms/ml, respectively. they were more active than antiulcer agents such as h2-blockers and cetraxate with mic90 values of greater than or equal to 1,600 and greater than 1,600 micrograms/ml, respectively. especially, clarithromycin, a new derivative of eryt ... | 1990 | 2212539 |
| evidence for gastric mucosal cell invasion by c. pylori: an ultrastructural study. | it is now generally accepted that campylobacter pylori is closely associated with peptic ulcer disease and chronic type b gastritis. whether c. pylori is the direct etiologic cause of either or both of these illnesses remains unclear. possible pathophysiologic effects of c. pylori are still a matter of debate and conjecture. utilizing a small group of patients with gastric ulcers and chronic gastritis, we examined the ultrastructural relationship between c. pylori and gastric cells. forty-eight ... | 1990 | 2212556 |
| campylobacter pylori interactions with gastric cell tissue culture. | many investigators have reported that gastric mucosal biopsies of patients with chronic gastritis and peptic ulcer disease show the presence of campylobacter pylori in a large majority of cases. histologic examinations of such tissues indicate a close approximation of c. pylori with gastric surface epithelial cells. a recent report has described both adherence and cell invasion of gastric cells by c. pylori. using a transmission electron microscope, we have examined the interaction between c. py ... | 1990 | 2212557 |
| [comparison of three methods for detecting campylobacter pylori and measurement of human antibody titers against the whole organisms]. | in order to detect campylobacter pylori in the gastric mucosa, three different methods as 1) culture of the organisms, 2) immunostaining by monoclonal antibody against the cells, and 3) urease test were compared. in the disease group, positive % of each methods was 64, 75 and 74. however, positive % common to the three methods was only 48. the corresponding rate of culture and urease tests, and that of culture and staining methods was 81% and 60%, respectively. therefore, it was concluded that u ... | 1990 | 2212754 |
| [examination of distribution of helicobacter pylori on gastric mucosa using dye endoscopy]. | 1990 | 2214287 | |
| preliminary study on the microbiology of campylobacter pyloridis and gastric histopathology. | biopsy samples were taken endoscopically from the antral-mucosa of 693 patients with peptic ulcer and chronic gastritis presenting dyspepsia symptoms. campylobacter pyloridis cultures were positive in 59 of 98 (60.2%) cases and histopathologically the organisms were found in 411 of 693 cases (59.3%). pathologically, campylobacter pyloridis was positive in 273 out of 300 patients with chronic superficial gastritis (91.0%), in 102 of 249 patients with chronic atrophic gastritis (40.9%), in 36 out ... | 1990 | 2214500 |
| [campylobacter pylori in patients with peptic ulcer and chronic gastritis: immunologic response]. | 1990 | 2214616 | |
| [campylobacter pylori and its role in the pathogenesis of selected diseases of the stomach and duodenum]. | 1990 | 2216966 | |
| clinical recognition and evaluation of peptic ulcer disease. | when a patient has epigastric pain that worsens 1 to 3 hours after meals, the possibility of peptic ulcer disease should be considered. completely typical clinical presentations in patients younger than age 50 justify empirical therapy when no physical or laboratory findings suggest a mimicking disorder. esophagogastroduodenoscopy should be undertaken when response to therapy is incomplete, symptoms recur quickly, or dyspeptic symptoms present for the first time in a patient older than age 50. w ... | 1990 | 2216988 |
| [chronic gastritis. pathogenesis, clinical aspects and therapy]. | based on clinical and histopathological features, three different types of chronic gastritis can be distinguished: gastritis a is confined to the proximal stomach and is the result of an autoimmunological process with antibodies against parietal cells and intrinsic factor. it is a rare disorder and may lead to pernicious anaemia. distal, antral gastritis b is caused by an infection of the gastric mucosa with helicobacter pylori (hp). its incidence increases with age (greater than 50% above age 5 ... | 1990 | 2218459 |
| [the histological diagnosis of chronic gastritis. a german proposal for an integrated nomenclature]. | the gastrointestinal pathology study group of the german pathological society has drawn up a proposal for a unifying nomenclature for the graduation and classification of gastritis. the severity of chronic gastritis is divided into 4 grades (minimal, light, moderate and severe) and the activity of the process is characterized by 3 grades (grade 1, 2 and 3 activity). in addition, the presence or absence of helicobacter pylori (formerly campylobacter pylori), the extent and type of intestinal meta ... | 1990 | 2218460 |
| [current perspectives in ulcer disease]. | 1. helicobacter pylori has been associated with chronic type-b gastritis, which in turn is always present in duodenal ulcer patients; therefore, it is likely that helicobacter pylori is an important cofactor in the pathogenesis of peptic ulcer disease. an eradication of helicobacter pylori is associated with the reduced ulcer relapse rate, but an effective therapy for eradication is not yet available and should be restricted to experimental protocols. 2. omeprazole is an antagonist of the proton ... | 1990 | 2218969 |
| [campylobacter pylori and treatment of duodenal ulcer]. | the authors subjected to endoscopic examination 90 patients with duodenal ulcers. from each patient they collected a bioptic specimen of the gastric antrum and duodenal bulbus for microbiological and histological examination. they found that for detection of c. pylori the microscopic examination was most useful. the presence of c. pylori in the gastric antrum was detected in 87% of the subjects and in the duodenal bulb only in 48%. the difference is significant at the 0.01 level. to 43 patients ... | 1990 | 2219764 |
| hyperplastic gastric polyps associated with persistent helicobacter pylori infection and active gastritis. | we report two cases of patients with 3-yr histories of upper gastrointestinal symptoms, hyperplastic gastric polyps, and active chronic gastritis. biopsies retrospectively stained with giemsa revealed the persistent presence of helicobacter pylori (hp) in gastric biopsies of both patients throughout the 3 yr. after treatment with amoxicillin and bismuth subsalicylate, both became asymptomatic, one demonstrating disappearance and recurrence of the gastric polyps in conjunction with the hp. these ... | 1990 | 2220735 |
| disaccharidases in duodenal biopsies in helicobacter pylori-positive patients. | 1990 | 2220753 | |
| association of helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy. | to determine the prevalence of helicobacter pylori in patients with non-ulcer dyspepsia and ulcer disease as well as in a control population undergoing endoscopic retrograde cholangiopancreatography (ercp) for suspected pancreatic or biliary disease. | 1990 | 2220879 |
| the prevalence of helicobacter pylori in nonulcer dyspepsia. importance of stratification according to age. | helicobacter pylori (formerly campylobacter pylori) is causally related to active antral gastritis and is highly associated with duodenal and gastric ulcers. however, the relationship of h pylori to nonulcer dyspepsia is less clear. we determined the presence of h pylori in unselected patients who were undergoing upper gastrointestinal tract endoscopy, and we found a prevalence of 37% in 110 patients with nonulcer dyspepsia that was similar to previous data. patients with nonulcer dyspepsia who ... | 1990 | 2222090 |
| [combination of glandular and foveolar hyperplasia of the gastric mucosa--a rare mixed type]. | in a 28 year-old man with epigastric pain endoscopy detected giant gastric folds and multiple superficial erosions. histologically a mixed form of glandular and foveolar hyper plasia of the gastric mucosa was suggested (ming's type iii). basal and pentagastrin stimulated secretion volume and acid output were moderately elevated, hypersecretion of protein was not found. serum levels of calcium and gastrin were normal, also after secretin stimulation. the mucosa of the corpus was extensively infes ... | 1990 | 2222791 |
| [advances in the research of pathogenicity of campylobacter pylori and epidemiology of its infection]. | 1990 | 2225011 | |
| in vitro susceptibility of helicobacter pylori to the new oral cephalosporins cefpodoxime, ceftibuten and cefixime. | the in vitro activity against 30 helicobacter pylori strains of three new third generation cephalosporins, cefpodoxime, ceftibuten and cefixime, which can be administered orally, was determined using an agar dilution technique under microaerophilic conditions. the mic50 and mic90 of cefpodoxime was 0.5 and 4.0 micrograms/ml respectively, of ceftibuten 2.0 and 8.0 micrograms/ml, and of cefixime 0.06 and 0.5 microgram/ml. all antibiotics showed good activity against helicobacter pylori, cefixime h ... | 1990 | 2226500 |
| natural history of congestive gastropathy in cirrhosis. the liver study group of v. cervello hospital. | in a prospective study of the natural history of congestive gastropathy, 212 consecutive cirrhotic patients (75 treated with sclerotherapy) were included. mean follow-up was 46 months. mild gastropathy (mosaiclike pattern) was found in 110 patients and severe gastropathy (granular mucosa with cherry spots) was found in 20. prevalence of helicobacter pylori, formerly campylobacter pylori, was 50% in patients without, 43% in those with mild, and 28% in those with severe gastropathy. congestive gas ... | 1990 | 2227271 |
| ranitidine in children with peptic ulcer and patients with pancreatic cystic fibrosis. | this article describes experience of the use of ranitidine in children with peptic ulcer and patients with pancreatic cystic fibrosis. ranitidine proved to be efficacious and well tolerated, the percentage of healing being 89.4%. ranitidine was also used in subjects with gastritis from campylobacter pylori, obtaining rapid regression of subjective symptoms. administration of ranitidine to cystic fibrosis patients improved the efficacy of the pancreatic extract, with consequent enhancement of dig ... | 1990 | 2228343 |
| gastrointestinal side-effects of octreotide during long-term treatment of acromegaly. | gastrointestinal side-effects of prolonged therapy (greater than 2 yr) with the long-acting somatostatin analog octreotide were studied in 10 acromegalic patients. after 2 yr of therapy, 6 of 10 patients had newly developed gallstones, complicated by cholangitis and jaundice in 1. serum vitamin b-12 concentrations declined in all 10 patients [from 380 +/- 32 to 172 +/- 21 pmol/l (mean +/- se); p = 0.023] and became abnormally low in 4. gastric biopsy specimens, obtained during gastroscopy (9 pat ... | 1990 | 2229321 |
| evaluation of two monkey species (macaca mulatta and macaca fascicularis) as possible models for human helicobacter pylori disease. | endoscopic, histologic, and microbiologic evaluations of 21 cynomolgus and 34 rhesus monkeys for naturally occurring helicobacter pylori infection were done. h. pylori was never isolated from any cynomolgus monkey, but was found in 12 rhesus monkeys. a general correlation existed between a positive culture and a gastric inflammatory response. inoculation challenges were then undertaken. four cynomolgus and five rhesus monkeys received two different h. pylori strains isolated from humans. five rh ... | 1990 | 2229353 |
| helicobacter pylori: has it a part in the lesion of the gastroesophageal reflux? | 1990 | 2230279 | |
| ultrastructure of a spiral micro-organism from pig gastric mucosa ("gastrospirillum suis"). | the ultrastructural features of a helical-shaped bacterium occurring in the stomach of pigs, within the mucus on the mucosal surface of antral pits, were examined. the bacterial cell had three to eight spiral turns, flattened and truncated ends and was approximately 4.0 microns long and 0.6 microns wide. in some sections, up to six flagella, about 22 nm in diameter, were seen arising from each pole. the cytoplasm contained sparse, irregular granules, numerous ribosomes and large single-layered m ... | 1990 | 2231673 |