Publications

ribosome inactivating proteins from rosaceae.	ribosome-inactivating proteins (rips) are widespread among higher plants of different taxonomic orders. in this study, we report on the rip sequences found in the genome/transcriptome of several important rosaceae species, including many economically important edible fruits such as apple, pear, peach, apricot, and strawberry. all rip domains from rosaceae share high sequence similarity with conserved residues in the catalytic site and the carbohydrate binding sites. the genomes of malus domestic ...	0	27556443
the perfect stage of leaf-spot of pear and quince.		1909	17777277
the nature of the growth rate.	1. the growth rate of organisms may be considered as a chemical reaction which gives the mature organism as its end-product. the organism grows at a definite rate which is, at any moment, proportional to the amount of growth yet to be made. 2. shoots of young pear trees measured at weekly intervals during the growing season showed a rate similar to that of an autocatalytic reaction. 3. young walnut trees showed distinct cycles of growth in a single season, but the growth in each cycle proceeded ...	1920	19871830
frederic poole gorham, 1871-1933.		1933	16559676
the histology and histopathology of the dental innervation: (section of odontology).	the presence of a perivascular neural plexus in the periodontal membrane suggests that the dental structures have both sensory and autonomic nerve supply. the fibres described by mummery are unaffected by section of the inferior dental nerve although there is marked degeneration in all demonstrable nerves. nerve-fibres have been observed describing simple and complex looping in the odontogenetic zone and others which, running tangentially between the odontoblast layer and the dentine, form a ver ...	1939	19992023
the significance of poly-phenolic metabolites of apple and pear in the host relations of venturia inaequalis and venturia pirina.		1957	13481331
[studies on phenolic components of pyrus communis. ii. arbutin content of pear leaves].		1957	13527184
[phenolic components of pyrus communis l. i. compilation of hitherto published data].		1957	13494187
[incidence of ursolic acid in the leaves of pyrus communis l].		1958	13545850
[findings on the phenolic content of pyrus communis. 5. occurrence of tannins in pear leaves].		1958	13566981
[studies on the phenolic constituents of pyrus communis. iv. content of arbutin in germinating pear seeds & distribution in young plants].		1958	13553772
[examination of phenolic content of pyrus communis. iii. effect of grafting on the arbutin content of the leaves of twigs & the base].		1958	13542184
the gorham proverbs test.		1960	14428116
[studies on the phenol content of pyrus communis l. part 6. the isolation and characterization of a new phenol compound].		1960	13825174
[massive osteolysis of gorham-stout].		1960	13841240
the effect of anxiety as measured by the taylor mas scale on performance on the gorham proverb tests.		1963	14042968
the flavonol glycosides in the fruit of pyrus communis l. cultivar bon chrétien.	1. two new flavonol glycosides were isolated from the fruit of pyrus communis l. cultivar bon chrétien. these were identified as isorhamnetin 3-rhamnogalactoside and a derivative of isorhamnetin 3-glucoside which was associated (possibly acylated) with an unknown aliphatic organic acid. 2. the melting point of isorhamnetin 3-glucoside isolated from bon chrétien pears is different from that of isorhamnetin 3-glucoside previously isolated from argemone mexicana and calendula officinalis. 3. isorha ...	1965	16749105
effect of gamma radiation on the ripening of bartlett pears.	gamma radiation at doses of 300 krad or more inhibits the ripening of bartlett pears (pyrus communis l.). immediately after irradiation there is a transitory burst of c(2)h(4), which subsequently declines in fruits subjected to inhibitory doses. ethylene production associated with ripening begins at the same time in unirradiated fruits and those subjected to noninhibitory doses, but the latter produces much more c(2)h(4) at the climacteric peak. fruits subjected to inhibitory doses produce low l ...	1966	16656274
sucrose density gradient distribution of mitochondrial protein and enzymes from preclimacteric and climacteric pears.	mitochondrial fractions isolated from pears (pyrus communis l.) at the climacteric minimum and peak were subjected to sucrose density gradient centrifugation. the distribution of protein and specific activities of 3 enzymes from this mitochondrial fraction were investigated.cytochrome oxidase specific activity remained associated with the particulate fraction and increased slightly during the period in which respiration of the whole fruit reached its climacteric peak. catalase and acid phosphata ...	1966	16656269
[abbreviated psychiatric evaluation scale (overall-gorham)].		1967	6065349
degradation of endosulfan and ethion on pears and pear and grape foliage.		1967	1270675
isolation, purification, and characterization of an endogenous root-promoting factor obtained from basal sections of pear hardwood cuttings.	basal segments taken from old home and bartlett pear hardwood cuttings collected at intervals during the rooting period in september were extracted with ethanol and fractionated by paper chromatography in different solvent systems. different zones on the chromatograms were bioassayed by the mung bean rooting test, which showed high levels of promotion in old home basal extracts when the cuttings were obtained during the period of maximum rooting. extracts from bartlett cuttings, however, showed ...	1967	16656535
[isolation and investigation of the pear bacteriosis agent in the western regions of the ukrainian ssr].		1968	5734161
cellular senescence, radiation damage to mitochondria, and the compensatory response in ripening pear fruits.	a compensatory response, viz. in vivo recovery from radiation damage to mitochondria, occurs in preclimacteric pear fruits (pyrus communis l.) treated with ionizing radiation. the compensatory response is absent or markedly impaired in senescent fruits irradiated at or near the climacteric peak. senescent cells failed to recover from harmful effects of radiation on: 1) mitochondrial yield, 2) in vivo incorporation of amino acids into mitochondrial protein, and 3) mitochondrial respiratory contro ...	1968	16656887
disappearing bone disease, morbus gorham. report of a case.		1968	5730317
s. whittington gorham 1885-1968.		1969	4912002
memorial. l. whittington gorham, m.d.		1969	4896317
new antibacterial agent isolated from the avocado pear.	a group of eight new long-chain aliphatic compounds recently isolated from the avocado and some derivatives thereof were tested for antibacterial activity on 13 different species of bacteria and a yeast. some of these compounds inhibited the growth of microorganisms. 1,2,4-trihydroxy-n-hepadeca-16-en was found to be the most active, inhibiting certain gram-positive bacteria at 4 mug/ml.	1970	4985830
[effects of oxytetracycline on pear vein yellows].		1971	5172302
mycoplasma-like bodies in the pear psylla vector of pear decline.		1971	5543285
importance of pear-tissue injury to infection by erwinia amylovora and control with streptomycin.		1972	5034224
effect of ph on penetration of naphthaleneacetic acid and naphthaleneacetamide through isolated pear leaf cuticle.	penetration of naphthaleneacetic acid through enzymatically isolated upper pear (pyrus communis l. cv. bartlett) leaf cuticle increased as the donor ph was decreased. naphthaleneacetamide penetration was not influenced by donor ph. the effect of ph on naphthaleneacetic acid penetration was reversible. higher receiver (simulated leaf interior) ph favored penetration of naphthaleneacetic acid. changes in the degree of dissociation, and hence polarity, as controlled by hydrogen ion concentration wa ...	1972	16658011
purification and some properties of two polyphenol oxidases from bartlett pears.	two polyphenol oxidases (enzymes a and b) from bartlett pear (pyrus communis) peelings were purified to electrophoretic homogeneity according to polyacrylamide gel by a combination of sephadex gel filtration, diethylaminoethyl cellulose chromatography and hydroxyl apatite chromatography. while the two enzymes differ electrophoretically at ph 9.3, chromatographically on hydroxyl apatite, and in the effect of ionic strength on activity, they are similar with respect to chromatography on diethylami ...	1973	16658592
initiation of ripening in bartlett pear with an antiauxin alpha(p-chlorophenoxy)isobutyric acid.	a vacuum infiltration technique was used to apply an anti-auxin, alpha-(p-chlorophenoxy) isobutyric acid to mature green pears (pyrus communis var. bartlett). application of alpha-(p-chlorophenoxy) isobutyric acid, at 0.02, 0.2, and 2.0 mm progressively accelerated the onset of chlorophyll degradation, softening, and co(2) evolution. the action of alpha(p-chlorophenoxy) isobutyric acid is apparently independent of ethylene, since the auxin analogue depressed ethylene evolution and could overcome ...	1973	16658566
[diagnostic identification of the so-called ideal profiles in the 16-item overall-gorham bprs (brief psychiatric rating scale) using an automatic computer].		1973	4718385
auxin inhibition of ripening in bartlett pears.	the effect of indoleacetic acid and 2,4-dichlorophenoxyacetic acid on the ripening of intact mature-green pears (pyrus communis var. bartlett) was investigated using a vacuum infiltration technique.the effects of indoleacetic acid and 2,4-dichlorophenoxyacetic acid at concentrations of 0.01, 0.1, and 1.0 mm each were studied on softening, degreening, and on ethylene and co(2) evolution. softening and degreening were inhibited increasingly in response to increased concentrations of indoleacetic a ...	1973	16658297
[gorham-stout syndrome caused by hemangiolymphangioma].		1974	4462968
fatty acid biosynthesis by avocado pear.		1974	4474578
microbial response to drought in a texas highplains shortgrass prairie.	the population of the microbial flora of a mixed blue gramma grass (bouteloua gracilis h. b. k.) and prickly pear (opuntia polyacantha haw.) prairie near amarillo, texas, was studied during 1971 after a severe drought. bacteria, fungi, and algae were estimated by plate count and terminal dilution procedures. rates of grass and paper decomposition were determined. the microbial flora of soil associated with bovine-grazed grass did not differ significantly from the flora associated with ungrazed g ...	1974	16350005
host-specific phytotoxic polysaccharide from apple tissue infected by erwinia amylovora.	a toxin isolated from apple fruit tissue infected by erwinia amylovora is 98 percent galactose in polymeric form, 0.375 percent protein, and has an average molecular weight of approximately 165,000. young shoots of rosaceous, but not nonrosaceous, species wilt in a manner characteristic of the disease when placed in toxin solutions with concentrations as low as 10 micrograms per milliliter. varieties of apple and pear susceptible to erwinia amylovora wilt in 1 to 3 hours, whereas resistant varie ...	1974	17738972
morphological changes of basophils in immunological reactions--effect of sodium cromoglycate.	the morphological changes in blood basophils, from patients with bronchial asthma, were studied in vitro during immunological reactions, with particular reference to interaction with anti-ige. anti-human ige results in an absolute reduction in basophil numbers in buffy coat preparations as well as basophil cytoplasmic degranulation. an increase in the number of pear-shaped (a-form) basophils is also observed. sodium cromoglycate impairs all these anti-ige induced basophil changes, providing furt ...	1975	806398
a new species of the genus bullera derx.	a new yeast species, bullera piricola, is described. the three strains studied were all isolated from the pear phylloplane. this species differs from all bullera species known at present by forming symmetrical as well as asymmetrical ballistospores. the problem of its integration into the genus bullera derx is discussed. an amended diagnosis of the genus bullera is given.	1975	1083203
conjugational transfer of genes determining plant virulence in erwinia amylovora.	a stable virulent donor strain (ea 178r1-99) of erwinia amylovora can transfer, by conjugation during a 3-h mating period, the gene or genes which determine(s) plant virulence to avirulent recipient strains (ea178-m64s1 and ea178-m173s1) of escherichia amylovora. the virulence of over 200 recombinant clones was tested; they all were as virulent on immature bartlett pear fruits (and, in the smaller series of strains tested, also, on pyracantha twigs) as was the parent donor strain. although the a ...	1975	1126916
[the state of the neural elements of the intestine in the aging organism].	the small intestine of the ageing human (15 cases from 70 to 88 years of age) and dogs (20 cases from 15 to 20 years of age) was treated by histological and neuro-histological methods. vacuolic dystrophy of neurons and hyperplasia, thickening of their processes were found. different formations up to 15 in number and from 20 to 60 mkm in size were revealed in the dog small intestine wall along the course of the nerve fibre. they were of pear-like, oval or round shape. inside these formations some ...	1975	1131029
a comparison of the properties in vitro of biphenyl 2- and 4-hydroxylase in the mesocarp from avocado pear (persea americana) and syrian-hamster hepatic tissue.		1975	1132558
comparative microscopical study of the gall bladder mucosa.	the gall bladder from 6 psammophis sibilans, 10 bufo regularis and 10 albino mice were extracted and prepared for microscopic examination. it was found that the mucosa of psammophis sibilans consisted of ovoid and polygonal cells which were occasionally binucleated cells with darkly stained nuclei and occasionally pear-shaped cells with vesicular nuclei and fine processes. these cells were arranged in three layers. apossible explanation for the different types of cells encountered and their arra ...	1975	1136701
[current status of the clinical evaluation of psychotropic drugs].	this paper deals with the analysis of different research conceptions and designs, according to different areas: i. human pharmacology and toxicology; ii. therapeutic prescriptions; iii. therapeutic effects; iv. thorough clinical testing. there is a strongly felt -eed of universally acknowledged rating scales for the assessment of the effects psychothropic drugs have on mental diseases. the lack of experimental models, together with the wide span of psychodinamic conceptions, overemphasizes the n ...	1975	1163268
development of the voicing contrast: perception of stop consonants.	perceptual development of the voicing contrast was investigated in two-year-old children, six-year-old children, and adults. subjects were required to identify prevocalic stop consonants from synthetic speech stimuli--bees/peas, bear/pear, dime/time, and goat/coat. the stimuli differed with respect to the acoustic cue, voice onset time (vot). identification functions for labial, apical, and velar stops were plotted for each subject. measurements of 50% crossover, lower and upper limits of the ph ...	1975	1186163
[yeast flora of plant rhizosphere and phyllosphere].	the species belonging to the genera cryptococcus and hansenula with saturnian spores predominate in the rhizosphere of agricultural plants. the sporiferous strains of debaryomyces, hanseniaspora apiculata, metschnikowia pulcherrima, and asporogenic candida krusei and trichosporon cutaneum prevail in the rhizosphere of wild plants. candida krusei and trichosporon cutaneum prevail in the rhizosphere of wild plants. the cultures of rhodotorula, candida krusei and metschnikowia pulcherrima are typic ...	1975	1226148
oxidative turnover of auxins in relation to the onset of ripening in bartlett pear.	pears (pyrus communis var. bartlett) kept in 100% o(2) showed an increase in the rate of softening, chlorophyll degradation, and ethylene evolution. the o(2) application could overcome, in part, the inhibition of ripening by 1 mm indoleacetic acid. ripening of pears was also accelerated by the application of solutions containing indoleacetic acid-oxidation products, obtained by an overnight incubation of 0.1 and 1 mm indoleacetic acid with traces of h(2)o(2) and horseradish peroxidase. although ...	1975	16659106
evidence for covalently attached p-coumaric acid and ferulic acid in cutins and suberins.	p-coumaric acid (4-hydroxycinnamic acid) and ferulic acid (4-hydroxy-3-methoxycinnamic acid) have been identified as constituents of cutin. their reduction products were isolated from a phenolic fraction released from the cutin of the fruits of apple, peach, pear, and two varieties of tomato and apple leaf by treatment with lialh(4) or liald(4). they were identified by combined gas chromatography and mass spectrometry. p-coumaric acid was present in all samples of cutin (0.07-0.53% by weight), w ...	1975	16659364
torulopsis bacarum, torulopsis pustula and torulopsis multis-gemmis sp. nov., three new yeasts from soft fruit.	three new species of yeasts isolated from fresh soft fruit are described. torulopsis pustula was isolated from blackcurrants, torulopsis bacarum from blackcurrants, strawberries and raspberries, and torulopsis multis-gemmis from raspberries. all differ from known species in the test substrates they utilize. in addition, cells of torulopsis pustula often form a bulbous projection near their apices from which budding takes place. these buds are frequently pear- or heart-shaped.	1975	1089748
ripening and in vitro retention of respiratory control by avocado and pear mitochondria.	the retention of respiratory control ("survival") by mitochondria held at 25 c was studied in relation to the ripening of two varieties of avocado (persea americana mill. var. ;fuerte' and ;hass') and one variety of pear (pyrus communis. l. var. ;bartlett') fruit. the survival of avocado mitochondria increased from 8 to 10 hours when isolated from unripe, preclimacteric fruit, to 48 hours when isolated from fully ripe, postclimacteric fruits. although rates of alpha-ketoglutarate oxidation, resp ...	1975	16659279
[the use of the brief psychiatric rating scale (bprs) by overall and gorham for the diagnosis of acute paranoid psychoses: evaluation of a german translation of the bprs (author's transl)].	a german translation of overall and gorham's "brief psychiatric rating scale" (bprs) has been used to select patients with acute paranoid psychoses for a drug trial and to evaluate the results of the treatment. the bprs proved very useful in screening, and as a reliable method to judge the global therapeutic outcome. the total score showed a high degree of interrater reliability; it also reflected a marked decrease of psychopathological symptoms at the end of the trial. interrater correlation co ...	1975	1233522
bromazepam versus diazepam in psychoneurotic inpatients.	a double blind between-groups trial was carried out to compare the effectiveness of the new benzodiazepine compound, bromazepam, (lexotan, ro 5-3350) as an anti-anxiety compound with that of diazepan. the fifty-eight psychoneurotic inpatients admitted to the trial were divided into two groups, "obsessives" and "neurotics", in order to assess any specific action of the drug. assessment was made by means of b.p.r.s. of overall and gorham, r.s.a.s. of hamilton, p.r.s. of wittenborn and i.m.p.s. of ...	1975	9648
productivity relations in a carex-dominated ecosystem.	seasonal and total primary productivity was measured for a carex meadow in southern quebec, canada. forty-five one-meter2 plots were sampled for dry weight biomass, species composition, structure (species density, diversity, height) and soil parameters including macronutrient concentrations (ca, k, mg, na, n, p), ph, organic matter, and water depth. shoot net productivity and litter decomposition rates were computed for 20-day intervals may-september, inclusive. relationships between all paramet ...	1976	28309101
[osteolysis of the bones of tarsus, metatarsus and articles of fingers during haemangioendothelioma. peripheral form similar to gorham-stout syndrome (author's transl)].		1976	1269036
changes in isoperoxidases during cold treatment of dormant pear embryo.	the number of isoperoxidases and the intensity of certain isozymes increased with increasing periods of stratification of pear (pyrus communis cv. bartlett) embryos. the presence of ga(3) or kinetin during stratification enhanced the activity of certain isoperoxidases, and these enhancements were blocked in the presence of aba which by itself had an inhibitory effect. enhancement in isoperoxidases of pear embryos during stratification was inhibited by 6-methylpurine and cycloheximide; and in the ...	1976	16659412
water permeability of isolated cuticular membranes: the effect of cuticular waxes on diffusion of water.	the water permeability of astomatous cuticular membranes isolated from citrus aurantium l. leaves, pear (pyrus communis l.) leaves and onion (allium cepa l.) bulb scales was determined before and after extraction of cuticular waxes with lipid solvents. in pear, the permeability coefficients for diffusion of tritiated water across cuticular membranes (cm) prior to extraction [p d(cm)] decreased by a factor of four during leaf expansion. in all three species investigated p d(cm) values of cuticula ...	1976	24424766
pilum pilum gen. et sp. n. (acanthocephala: echinorhynchidae) from freshwater fishes of the southeastern united states.	pilum pilum gen. et sp. n. is described from the warmouth, lepomis gulosus (cuvier); brown bullhead, ictalurus nebulosus (lesueur); yellow bullhead, i. natalis (lesueur); redbreast sunfish, l. auritus (linnaeus); bluegill, l. macrochirus rafinesque; spotted sunfish, l. punctatus (valenciennes); and redfin pickerel, esox americanus (gmelin), from the alabama river drainage, brown bullhead from the mobile bay drainage in alabama, and pirate perch, aphredoderus sayanus gilliams, from an atlantic co ...	1976	1255353
development of the voicing contrast: a comparison of voice onset time in stop preception and production.	the acoustic cue voice onset time (vot) was used to study development of the voicing contrast in 10 two-year-old children, 10 six-year-old children, and 20 adults. thirty utterances of the words bees, peas, bear, pear, dime, time, goat, and coat were elicited from each subject, vot measured, and individual production distributions for labial, apical, and velar stops plotted. significant age-related differences were shown for mean vot, mean lead time for voiced stops, range of the same words that ...	1976	1271805
the basilar pontine gray in the adult monkey (macaca mulatta): a golgi study.	in golgi preparations of the adult monkey (macaca mulatta) two types of neurons are distinguished in the pontine gray: (1) larger neurons which impregnate most frequently and (2) smaller neurons which impregnate rarely. the former are judged to be projection neurons with myelinated axons because only the initial segments of their axons impregnate, while the latter are judged to be intrinsic neurons since they appear to participate only in the local circuitry of the pontine gray. the projection n ...	1976	819468
[ultrastructure of the epithelium of the major pancreatic duct in sheep].	light-and electron-microscopic and some histochemical investigations on the epithelium or the ductus pancreaticus major were carried out in sheep. at least six different cell types are recognizable: (1) nondifferentiated duct cells; (2) cells containing apical secretory granules; (3) goblet cells; the mucosubstances of type 2 and 3 are pas- and alcian-blue-positive, also reacting wih methenamine silver; (4) ciliated cells, containing a single cilium with the microtubular pattern 9+2; (5) tuft ce ...	1976	970105
the morpho-histology of the pituitary glands in two freshwater major carps of india, labeo rohita (ham.) and cirrhinus mrigala (ham.).	1. the pituitary gland in labeo rohita and cirrhinus mrigala is a small, pear-shaped, whitish, soft body situated in a cavity -- the sella turcica. the gland is of the lepto-dorso basic type. 2. it consists of the neurohypophysis and adenohypophysis. the latter comprises three lobes viz., the rostral pars distalis, the proximal pars distalis and the pars intermedia. 3. the neurohypophysis branches into the pars distalis, extends into the pars intermedia and ramifies extensively. it is composed o ...	1976	984440
light microscopy and scanning electron microscopy of bathmostomum sangeri cobbold, 1879, of elephants.	bathmostomum sangeri is an intestinal parasite of the elephant. males measured 12.15-14.25 mm in length; females measured 14.98-17.68 mm in length. buccal capsule is well-developed and funnel-shaped. there is a raised and transverse fissure ridge around the oral margin. the internal wall of the buccal capsule is raised into a series of circular ridges or lamellae. teeth or cutting plates could not be seen. spicules are stout, wing-like structures. the telamon is pear-shaped, but a gibernaculum i ...	1976	1035986
acute poisoning in a puppy caused by the balsam pear (momordica charantia).		1976	1047586
characterization of a strain of methanospirillum hungatti.	the results of morphological, base ratio, nutritional, temperature, and ph studies on a strain of methanospirillum hungatii, isolated from an anaerobic pear waste digester, are described. the isolate, designated as strain gp 1, was compared with some of the characteristics of type-strain m. hungatii jf 1. strain gp 1 is gram-negative, weakly motile, and a strict anaerobe with a guanine plus cytosine (g +c) content of 46.5 mol%. the preferred substrates for methane production are hydrogen, carbon ...	1976	10074
isolation of a guanylate cyclase inhibitor from the balsam pear (momordica charantia abreviata).		1977	20099
[unsaponifiable fractions of the avocado and soy bean in gyneocology].	the experimental work of robert on the action of the unsaponifiable fractions of the avocado pear and soya bean on inflammatory granulomata of the rat gives rise to the supposition that these have a selective action on inflamed connective tissue by a process of katabolism of collagen through proteolytic enzymes. we have used this anti-inflammatory and collagenolytic action in gynaecology, with favourable results particularly in post-inflammatory and post-infective conditions as well as scarring ...	1977	558245
gross and microscopic anatomy of the biliary tract of the ferret.	the gross and microscopic anatomy of the biliary tract of the ferret was studied. the liver consisted of six separate lobes. the coronary ligament was not present. histologically, it was very similar to that of man. the gall-bladder was present and was a pear-shaped sac. its muscle coat was very thick and well developed. hepatic ducts were multiple. minor hepatic ducts formed three major ducts, the left, central and the right. a single common hepatic duct was not present. the cystic duct general ...	1977	848264
fusiform erythrocytes resembling sickle cells in angora goats: light and electron microscopic observations.	fresh blood from nine mature non-pregnant angora goats was found to contain a varying proportion of spindle-shaped, fusiform, triangular, pear-shaped, and other bizarre forms of erythrocytes in addition to normal discoid biconcave erythrocytes. the number of spindled and fusiform erythrocytes varied from 2 to 66 per cent, with two goats having such cells in excess of 50 per cent. other aberrant forms of erythrocytes ranged from 3 to 54 per cent. although the aberrant erythrocytes seemed to be pr ...	1977	860092
plant cuticles are polyelectrolytes with isoelectric points around three.	the isoelectric points of isolated cuticles from citrus aurantium l. (3.15), prunus armeniaca l. (3.45), and pyrus communis l. (2.90) leaves were determined from membrane potentials. at ph values below the isoelectric point, cuticular membranes carry a net positive charge and are permselective to anions (determined using (82)br(-)). above the isoelectric point, they carry a net negative charge and are permselective to cations (determined using (24)na(+)). there are no gradients of fixed charges ...	1977	16659804
temperature-dependent changes in the polysomal population of senescent (ripening) pear fruit.	a loss and recovery of polysomes coincident with the temperature-dependent interruption and resumption of pear fruit (pyrus communis, l.) senescence establishes a close correlation between the presence of protein-synthesizing machinery and the progression of senescence and ripening.	1977	16660215
effect of aminoethoxy analog of rhizobitoxine on ripening of pears.	ripening reactions in pears (pyrus communis l.) were differentially affected by an aminoethoxy analog of rhizobitoxine (l-2-amino-4-[2-aminoethoxy]-trans-3-butenoic acid) (aar). ethylene production of both ;anjou' and ;bartlett' pears was inhibited by aar. decrease in firmness, increase in protein n and soluble pectin were delayed by aar in ;anjou' but not in ;bartlett' pears. while loss in malic acid was retarded in ;anjou' pears, rates of citric acid accumulation and malic acid reduction were ...	1977	16659890
involvement of hydrogen peroxide in the regulation of senescence in pear.	endogenous peroxide levels in pear fruit (pyrus communis) were measured using a titanium assay method, and were found to increase during senescence in both bartlett and bosc varieties. application of glycolic acid or xanthine, serving as substrates for the formation of h(2)o(2), increased the peroxide content of the tissue and accelerated the onset of ripening, as measured by increased softening and ethylene evolution. application of ethylene also induced increased peroxide levels. ripening proc ...	1977	16659863
concanavalin a-mediated agglutination of plant plastids.	cucumber (cucumis sativus l.) and pear (pyrus domestica medik.) fruit proplastids, and pea (pisum sativum l., cv. meteor) leaf chloroplasts, extracted by osmotic rupture of protoplasts isolated after degradation of the cell walls by cellulase and pectinase, agglutinated in the presence of con a. agglutination of cucumber proplastids was inhibited by anti-con a and by methyl α d-gluco/manno pyranosides but not by methyl α d-galactopyranoside. fluorescein isothiocyanate-conjugated con a (fitc-con ...	1978	24413938
[ultrastructural and histochemical aspects of the rodlet cells from the bulbus arteriosus of cyprinus carpio l. (pisces: cyprinidae) (author's transl)].	morphological details of the "stäbchendrüsenzellen" (plehn), rodlet cells syn. pear-shaped cells of the endothel from the bulbus arterious of carps were studied in the electron microscope. from morphological characteristics, especially from the development of desmosomes with adjacent endothelial cells, it becomes evident, that the cells in question, which are very common in teleostei, are not of parasitic nature. specific protrusions of the apical cell poles towards the arterial lumen are indica ...	1978	686392
asymmetrical jelly secretion of zygotes of pelvetia and fucus: an early polarization event.	five hours before germination the zygotes of pelvetia fastigiata adhere to their substrate. a jelly layer covers the entire cell but most of the transparent jelly, artificially outlined by a layer of resin beads, is secreted at the prospective rhizoid pole. if the direction of the growth-orienting light is shifted after the asymmetrical secretion has already started, the direction of the secretion is also shifted. the polarization axis can be predicted by the site of the intensive jelly secretio ...	1978	24414363
comparative analysis of tissue esterases of the zebra danio (brachydanio rerio) and the pear danio (b. albolineatus) by disc gel electrophoresis.		1978	1277802
gross, histomorphological and histochemical changes in thyroid gland of goat with age. ii. occurrence of ultimobranchial follicles.	occurrence and histomorphology of ultimobranchial follicles in the thyroid glands of 26 goats of six different age groups (ranging from 20 days to above five years) was studied. the occurrence of ultimobranchial follicles was 38.46%. in 15.38% of the cases, it was found with and in 23.08% without any association of the thymic tissue. its association with parathyroid tissue has also been recorded in one of the goats aged 7 months 11 days. their size and shape varied greatly and were narrow and wi ...	1978	637309
topography of the myosin molecule as visualized by an improved negative staining method.	an improved negative staining method has been used to visualize monomeric myosin molecules. each lobe (subfragment 1) of the molecule looked like an elongated pear, and the widths of the thick and thin portions were about 95 and 55 a, respectively. the length of each lobe was about 210 a. it appeared capable of moving azimuthally and altitudinally, utilizing its juncture with the rod portion as the base. the rod portion of the molecule was about 1400 a long and 30 a wide. it also appeared to pos ...	1978	641037
the carbohydrate linkage site of cow colostrum trypsin inhibitor.	cow colostrum trypsin inhibitor (chromatographic form aiv[7])was subjected to basic conditions that favour beta-elimination of carbohydrates from o-glycosidic linkages. the unchanged carbohydrate composition and the unchanged values for serine and threonine indicate the presence of an alkali-stable n-glycosidic bond to asparagine. from a tryptic digest of s-aminoethylated inhibitor the glyco-decapeptide (residues 24 through 33) was isolated. the carbohydrate composition was identical with that o ...	1978	649052
[electron microscopic study of perisomatic process development in cerebellar cortex pyriform neurons during prenatal human ontogenesis].	perisomatic processes are shown to be temporary morphological formations that appear within 16-28 weeks of embryogenesis, their development being characterized by a certain succession. perisomatic processes form multiple synaptic complexes with axon endings of unknown origin adherent to perikaryons of pear-shaped neurons. these axon endings are supposed to belong to afferent climbing fibers of cerebellum stimulating differentiation of pear-shaped neurons, localization of these fibers causing a c ...	1978	684839
food sensitivity reported by patients with asthma and hay fever. a relationship between food sensitivity and birch pollen-allergy and between food sensitivity and acetylsalicylic acid intolerance.	among adult patients with bronchial asthma and/or allergic rhinitis undergoing allergological investigation with skin test, nasal provocation test and rast, 1129 answered a questionaire regarding food sensitivity (fs). 276 (24%) of the patients reported some kind of allergic symptoms on eating or handling various foods, of which hazel nut, apple and shell fish were the most often named. females reported fs more often than males. a correlation was found between birch pollen allergy and fs with nu ...	1978	717703
inhibition of growth and guanylate cyclase activity of an undifferentiated prostate adenocarcinoma by an extract of the balsam pear (momordica charantia abbreviata).	we have recently described the presence of a guanylate cyclase gtp pyrophosphate-lyase (cyclizing), ec 4.6.1.2 inhibitor (gci) in an aqueous extract of the balsam pear (momordica charantia abbreviata). because the guanylate cyclase-cyclic gmp system is though to be involved in cell growth, dna and rna synthesis, and possible malignant transformation, we examined the effect of the aqueous extract containing gci on an undifferentiated adenocarcinoma of the rat prostate and concanavalin-a-stimulate ...	1978	24847
long-term cultivation of plasma cell leukemia cells and autologous lymphoblasts (lcl) in vitro: a comparative study.	two long-term cell lines were established in vitro from the peripheral blood of a patient with plasma cell leukemia: one line with plasma cell proliferation, the other with lymphoblastoid cell proliferation (lcl). the 9-month-old plasma cell line showed the typical morphology of plasmoblasts. the cells neither had b- nor t-lymphocyte characterisitics, were ebv negative, and showed aneuploidy with various marker chromosomes, including the 14 q+ marker. the cytogenetic findings indicate a monoclon ...	1978	207377
14c-dopamine microinjected into the brain-stem of the rat: dispersion kinetics, site content and functional dose.	a morphological analysis was undertaken of both the dispersion characteristics and tissue content of dopamine (da) microinjected acutely into the brain-stem of the anesthetized rat. 14c-da, with a specific activity of 56-62 mci/mmol, was infused unilaterally into the pars compacta of the substantia nigra in one of four test volumes: 0.5, 1.0, 4.0 or 8.0 microliters. the concentration of the 14c-da solution was 1.0 microci/microliter, equivalent to 3.01 micrograms/microliters, which was delivered ...	1978	318183
sexual conjugation in yeast. cell surface changes in response to the action of mating hormones.	in the yeast saccharomyces cerevisiae, sexual conjugation between haploid cells of opposite mating type results in the formation of a diploid zygote. when treated with fluorescently labeled concanavalin a, a zygote stains nonuniformly, with the greatest fluorescence occurring at the conjugation bridge between the two haploid parents. in the mating mixture, unconjugated haploid cells often elongate to pear-shaped forms ("shmoos") which likewise exhibit asymmetric staining with the most intense fl ...	1979	379012
[the human dental pulp as viewed through a scanning electron microscope (author's transl)].	the human dental pulp was examined using a scanning electron microscope. the odontoblasts are pear-shaped and have a fine-grain surface structure. tomes' process divides into fine branches before entering the predentin. very few fibroblasts were found. these had stronger cell processes at the two terminal poles. adhering to their surfaces were fine fibers. collagenous and nerve fibers could not be accurately identified in the rich fibrillary network of the pulp. stronger nerve fasciculi were rea ...	1979	157024
ultrastructural changes in the cell walls of ripening apple and pear fruit.	ultrastructural changes in the cell walls of "calville de san sauveur" apples (malus sylvestris mill) and "spadona" pear (pyrus communis l.) fruit were followed during ripening. in apple, structural alterations in cell walls became apparent at advanced stages of softening and showed predominantly dissolution of the middle lamella. in pears softening was also associated with the dissolution of the middle lamella, and in addition a gradual disintegration of fibrillar material throughout the cell w ...	1979	16660931
polyribosomes from pear fruit: changes during ripening and senescence.	polysome profiles were examined from lyophilized peel tissue of ripening pear (pyrus communis, l. var. passe-crassane). messenger rna chains bearing up to eight ribosomes (octamers) were resolved and exhibited the highest absorption peak when ribonuclease activity was eliminated during extraction. neither normal ripening nor the increase of large polyribosomes that normally accompanies ripening and senescence of the fruit occurred when pretreatment at 0 c was omitted. normal ripening and increas ...	1979	16661101
senescence of pear fruit cells cultured in a continuously renewed, auxin-deprived medium.	auxins and cytokinins support cell division in tissue and cell cultures. in cytokinin-independent pear (pyrus communis) cells, omission of 2,4-dichlorophenoxyacetic acid (2,4-d) from the medium for two successive transfers leads to rapid cell lysis, unless the osmolarity is raised to 0.4 molar with mannitol. use of this system (nutrients plus mannitol minus 2,4-d) for the study of cell senescence was explored both in batch culture and in a system designed to permit medium renewal without withdra ...	1979	16661060
pear malic enzyme: some physical and immunochemical properties.	some physical and immunochemical characteristics of nadp malic enzyme from climacteric pear (pyrus communis l. var passe-crassane) are described. the enzyme which has a molecular weight of about 224 000 d and a sedimentation coefficient of about 9.6 s, is formed by the association of four sub-units. we were not able to isolate isozymes by electrophoresis or by immunochemistry.	1979	115065
[radiodiagnosis of the gorham-stout syndrome (author's transl)].		1980	7459960
hospital size: manage...be they large or small.	in this article r. banyard, assistant hospital administrator, and m. gorham, hospital administrator, at the northern general hospital, discuss government statements on the size of future hospitals and relate these to the current debate on patients first.	1980	10247176
cell wall metabolism in ripening fruit: ii. changes in carbohydrate-degrading enzymes in ripening ;bartlett' pears.	mature ;bartlett' pear (pyrus communis) fruits were ripened at 20 c. fruits at different stages of ripeness were homogenized, and extracts of the low speed pellet (crude cell wall) were prepared. these extracts contained polygalacturonase, pectin esterase, and activity against seven p-nitrophenyl glycoside substrates. polygalacturonase, alpha-galactosidase, and alpha-mannosidase increased in activity as the fruit ripened. cellulase and activities against pear wall xylan and arabinan were absent ...	1980	16661276
cell wall metabolism in ripening fruit: i. cell wall changes in ripening ;bartlett' pears.	;bartlett' pear (pyrus communis) fruits were picked at the mature, green stage and ripened at 20 c. fruits at different stages of ripeness (based on flesh firmness) were homogenized, and the sugar and uronic acid contents of cell wall and soluble polysaccharides were determined. substantial amounts of galacturonic acid and arabinose were lost from the wall fraction as the fruit ripened. most of this cell wall material was recovered, in an 80% (volume/volume) ethanol-insoluble form, from the solu ...	1980	16661275
effects of aminoethoxyvinylglycine and countereffects of ethylene on ripening of bartlett pear fruits.	pear fruits (pyrus communis l. var. bartlett) were treated with solutions containing aminoethoxyvinylglycine (avg) using a modified vacuum infiltration method that introduced 4.3 milliliters solution per 100 grams tissue. at concentrations of 1 millimolar, avg strongly inhibited ethylene production and delayed for 5 days the respiratory climacteric and accompanying ripening changes in skin color and flesh firmness. avg was less effective in inhibiting the ripening of more mature fruits. fruit in ...	1980	16661193
[spontaneous osteolysis of the carpus (gorham syndrome?)].	osteolysis following trauma (vanishing bone) is well known. its appearance is not typical to any special anatomical site. a massive osteolysis of the carpus was described by gorham in 1955. in subsequent years this type of osteolysis was found together with progressive nephropathy. the author presents a case of exclusively carpal osteolysis without initial trauma, not accompanied by nephropathy, starting out at the age of six. the carpal bones were completely destroyed by the age of eleven.	1980	7250806
pleiotropic mutations at the tup1 locus that affect the expression of mating-type-dependent functions in saccharomyces cerevisiae.	the umr7-1 mutation, previously identified in a set of mutants that had been selected for defective uv-induced mutagenesis at can1, affects other cellular functions, including many of those regulated by the mating-type locus (mat) in heterothallic saccharomyces cerevisiae. the recessive umr7-1 allele, mapping approximately 20 cm distal to thr4 on chromosome iii, causes clumpy growth in both a and alpha cells and has no apparent effect on a mating functions. however, alpha umr7 meiotic segregants ...	1980	17249022