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immunologic reactions with tobacco mosaic virus.1. antisera were produced, separately, in rabbits to normal sap from healthy turkish tobacco plants and to irus-sap from tobacco plants, affected with mosaic disease. 2. the immunologic reactions of the antisera were studied by means of: (a) alexin-fixation tests. (b) precipitation experiments, including: precipitin-absorption tests with the same tobacco virus multiplied in tobacco, tomato, pepper, and petunia plants. (c) experiments with the inactivation properties of both antisera and normal s ...192919869591
specificity of the precipitin reaction in tobacco mosaic disease.1. leaf extracts of sudan grass, hippeastrum equestre herb., lily, and abutilon striatum dicks. (a. thompsoni hort.), each affected with its respective mosaic disease, and peach affected with yellows disease, were tested for their ability to precipitate antiserum for virus extract of tobacco mosaic disease. no precipitate occurred. 2. nicotiana glutinosa l., n. rustica l., and martynia louisiana mill. were added to the list of hosts of tobacco mosaic virus which have been tested with antiserum f ...193119869933
rod-shaped particles in tobacco mosaic virus demonstrated by stream double refraction. 193317789591
the action of high frequency sound waves on tobacco mosaic virus. 193417743815
possible chemical nature of tobacco mosaic virus. 193417749258
the relation of stream double refraction to tobacco mosaic virus. 193517771202
isolation of a crystalline protein possessing the properties of tobacco-mosaic virus. 193517743301
a serlogical of the absolute concentration of tobacco mosaic virus. 193517807898
inactivation of tobacco-mosaic virus by x-rays. 193617806557
the ultracentrifugal crystallization of tobacco mosaic virus protein. 193617769019
the isolation of crystalline tobacco mosaic virus protein from diseased tomato plants. 193617756690
the inactivation of crystalline tobacco-mosaic virus protein. 193617783494
purification of tobacco mosaic virus and production of mesomorphic fibers by treatment with trypsin. 193717784206
genes affecting response of nicotiana tabacum hybrids to tobacco-mosaic virus. 193717758401
the isolation of tobacco ring spot and other virus proteins by ultracentrifugation.a high molecular weight crystalline protein, possessing the properties of ring spot virus and differing markedly from tobacco mosaic virus protein in its physical, chemical and serological properties, has been isolated by means of an ultracentrifuge from turkish tobacco plants diseased with tobacco ring spot virus. ultracentrifugal methods were also used to demonstrate that high molecular weight proteins are characteristic of other virus diseases. the concentration of the different virus protein ...193717732936
tobacco-mosaic virus concentrated in the cytoplasm. 193817736948
an estimate of the relative dimensions and diffusion constant of the tobacco-mosaic virus protein. 193817788531
the molecular weight and shape of tobacco mosaic virus protein. 193817788532
crystallization of tobacco-mosaic virus protein. 193817832169
the disintegration of tobacco mosaic virus preparations with sodium dodecyl sulphate. 193816746802
influence of host factors on neuroinvasiveness of vesicular stomatitis virus : iii. effect of age and pathway of infection on the character and localization of lesions in the central nervous system.it will be well to restate the main problem at this point and to examine how far the accumulated data can help to elucidate it. the problem is this: why are old mice generally resistant to all forms of peripheral inoculation of vesicular stomatitis virus when intracerebral injection is equally fatal for mice of all ages? the results of experiments in which the presence of virus was demonstrated by animal passage suggested that the reason can perhaps be found in (a) the different mechanisms of vi ...193819870715
the measurement of surface films formed by hemocyanin, tobacco mosaic virus, vaccinia, and bacterium gallinarum. 193819873070
the partial reactivation of formolized tobacco mosaic virus protein.a marked reactivation of tobacco mosaic virus protein that has been partially or completely inactivated by formaldehyde was obtained by dialysis at ph 3. the activity of partially inactivated virus proteins was generally increased about 10-fold by the reactivation process. it was also found possible to reactivate completely inactive preparations to an appreciable extent. it was shown that the inactivation and the subsequent reactivation cannot be explained by the toxicity of the formaldehyde or ...193819873099
on the molecular weight of the tobacco mosaic virus protein. 193917809481
an estimate of the maximum value for the molecular weight of the tobacco mosaic virus protein. 193917787744
disintegration of tobacco mosaic virus in urea solutions. 193917788438
the effect of host nutrition on concentration of tobacco-mosaic virus. 193916653600
reversible inhibition of tobacco mosaic virus in living cells with 0.0002 molar sodium cyanide. 194017839406
the reactions of iodine and iodoacetamide with native egg albumin.the following experimental results have been obtained. 1. native egg albumin treated with iodine and then denatured no longer gives a nitroprusside test or reduces dilute ferricyanide in neutral duponol pc solution. 2. more iodine is needed to abolish the ferricyanide reduction if the reaction between native egg albumin and iodine is carried out at ph 6.8 than if the reaction is carried out at ph 3.2. at ph 6.8 iodine reacts with tyrosine as well as with cysteine. 3. cysteine and tryptophane are ...194019873158
solubility studies on purified tobacco mosaic virus.different samples of purified tobacco mosaic virus show a relatively wide variation in solubility in ammonium sulfate solution. this variation and the type of solubility curve obtained in the presence of varying amounts of solid phase show that the purified virus whether isolated by mild treatment with ammonium sulfate or by ultracentrifugation is not a homogeneous chemical substance but contains more soluble and less soluble virus fractions of comparable specific activities. long contact with s ...194019873187
some effects of iodine and other reagents on the structure and activity of tobacco mosaic virus.1. denatured tobacco mosaic virus has a number of sh groups corresponding to its total sulfur content of 0.2 per cent. the sh groups were estimated by titration with ferricyanide, tetrathionate, and p-chloromercuribenzoate in guanidine hydrochloride solution and by reduction of the uric acid reagent in urea solution. 2. the sh groups of tobacco mosaic virus or their precursors can be abolished by reaction of the native form of the virus with iodine. 3. tobacco mosaic virus whose sh groups have b ...194119873243
x-ray and crystallographic studies of plant virus preparations. iii.these papers give an account of an optical and x-ray examination of preparations of plant virus substances isolated by bawden and pirie, in particular of those of tobacco mosaic disease. they open with a historical survey of the work, indicating the order in which new phenomena were discovered. the subsequent treatment is divided into three parts: i. introduction and preparation of specimens. ii. modes of aggregation of virus particles. iii. (1) the structure of the particles. (2) biological imp ...194119873256
acetyl and phenylureido derivatives of tobacco mosaic virus. 194117842482
correlation of activity per unit weight of tobacco-mosaic virus with age of lesion. 194117774032
inhibition of increase and activity of tobacco-mosaic virus under nitrogen-deficient conditions. 194116653694
influence of nitrogen supply on the rate of multiplication of tobacco-mosaic virus. 194116653732
specific biological activity of tobacco-mosaic virus as influenced by age of lesion and nitrogen supply. 194216653769
infectivity of extracted, unpreserved tobacco mosaic virus retained 28 years. 194217789130
on the size and shape of the tobacco mosaic virus protein particle. 194217797120
the reversible inactivation of tobacco mosaic virus by crystalline ribonuclease.the reversible inactivation of tobacco mosaic virus by crystalline ribonuclease is reported. studies on the effect of time of standing on the amount of inactivation, and on the effect of dilution and repeated high speed centrifugation on the recovery of virus activity, and the preparation of an insoluble virus-enzyme complex show that the inactivation is brought about at least in part by a combination between virus and enzyme. the significance of the fact that ribonuclease has no detectable effe ...194219873289
the preparation and use of tobacco mosaic virus containing radioactive phosphorus.normal and tobacco mosaic-diseased turkish tobacco plants were grown in sand for a period of several weeks, during which they were fed daily a complete nutrient solution to which had been added disodium phosphate containing radioactive phosphorus. determinations were made of the distribution of radioactive phosphorus in different fractions such as the wash from the sand and roots, the press cake obtained on pressing the juice from the plants, the protein and protein-free portions of the supernat ...194219873320
stream double refraction studies on the orientation of tobacco mosaic virus particles. 194417798395
the effect of formaldehyde and mercuric chloride on tobacco mosaic virus. 194416747741
combination of potato virus x and tobacco mosaic virus with pepsin and trypsin. 194416747768
electron shadow micrography of the tobacco mosaic virus protein.two improvements are described in the use of shadow electron micrography for the observation of particles of macromolecular dimensions. one involves the substitution of gold for chromium as shadowing metal. the thinner gold film that can be employed gives a truer representation of the shape of particles so small that shape and size are significantly altered by the thickness of the shadowing metal deposited on them. the other consists in metal-shadowing small particles deposited on a very smooth ...194517739444
on the rate of inactivation of tobacco mosaic virus by potassium salicylate. 194521006106
the effects of infection of tobacco plants (nicotiana tabacum) with tobacco mosaic virus on some of the properties of the protein present in the leaves. 194521006109
field strains of tobacco-mosaic virus. 194621014259
an electron microscope study of the contents of hair cells from leaves diseased with tobacco mosaic virus. 194621002132
inhibition of phosphorylation of glucose in mouse brains by viruses and its prevention by preparations of diphosphopyridine nucleotide.1. inhibition of glucose utilization in homogenates of brains of mice infected with poliomyelitis virus (lansing strain) is reported. the inhibition occurs with glucose, or fructose-6-phosphate as substrate. no inhibition occurs in the presence of hexosediphosphate. 2. brain homogenates of mice infected with the theiler fa strain of mouse encephalomyelitis virus show inhibition ranging between 45 and 85 per cent (average 73 per cent). 3. purified preparations of the lansing and the theiler fa st ...194619871563
electron-microscopy of viruses; state of aggregation of tobacco mosaic virus. 194620279218
an electron microscope study of tobacco mosaic virus at different stages of infection. 194620280148
electron microscope studies on tobacco-mosaic virus. 194720281568
the identification of three mononucleotides from tobacco mosaic virus nucleic acid. 194720285056
immunochemical studies with tagged proteins; the distribution of tobacco-mosaic virus in the mouse. 194720285152
comparative properties of purified preparations of two distinctive strains of tobacco mosaic virus obtained from diseased turkish tobacco and phlox plants. 194720287909
interaction between tobacco mosaic virus and bovine serum albumin. 194720296072
light scattering studies of tobacco mosaic virus. 194720240512
viscosity studies on the association of tobacco mosaic virus. 194720255276
immunochemical studies on tobacco mosaic virus: the reaction with homologous rabbit antiserum. 194720264684
immunochemical studies on tobacco mosaic virus: the host-strain relationship. 194720264685
immunochemical studies on tobacco mosaic virus: the specificity of preparations of two strains isolated from the sap and the fibrous residue of infected plants. 194720264686
immunochemical studies on tobacco mosaic virus: the serological behavior of sonic treated tobacco mosaic virus. 194720264687
further studies on the physical states assumed by tobacco mosaic virus in vitro. 194720270650
electron microscope studies of bahlem, rothamsted, and princeton samples of tobacco mosaic virus. 194720270770
the size of the particles of some strains of tobacco mosaic virus as shown by the electron microscope. 194720270771
the utilization for animal growth of tobacco mosaic virus as a sole source of protein in the diet. 194720272122
studies on the sonic treatment of tobacco mosaic virus.centrifugally purified samples of tobacco mosaic virus were subjected to intense sound vibrations of 9,000 cycles per second for 0, 2, 8, 16, 32, and 64 minutes. the viscosity and stream birefringence of the samples decreased with time of sonic treatment, but no chemical changes were found. electron micrographs of the samples show that the particles are broken perpendicular to their long axis. in the untreated sample 62 per cent of the particles are about 280 mmicro in length. as sonic treatment ...194719873522
crystallization of tobacco mosaic virus by serum albumin. 194720343135
a chromatographic method for the detection of tobacco-mosaic virus in juice from diseased turkish tobacco plants. 194718895502
[not available]. 194720268263
the constancy of chemical composition and infectivity per unit weight of tobacco mosaic virus protein prepared over a period of years. 194818910569
the thermal denaturation of tobacco mosaic virus in relation to hydrostatic pressure. 194818938383
longevity of tobacco mosaic virus; in vitro life of the pure virus in buffer solution at ph 4. 194818865528
interaction between tobacco mosaic virus and bovine serum albumin. 194818865616
the effect of nucleic acids and of carbohydrates on the formation of streptolysin.1. ribonucleic acid of yeast causes the formation of a potent hemolysin in broth cultures of streptococcus pyogenes. 2. the hemolysin whose formation is induced by yeast ribonucleic acid appears to be identical with streptolysin s. 3. desoxyribonucleic acid, products of acid or alkaline hydrolysis of ribonucleic acid, or many other substances tested, fail to produce a similar effect. 4. digestion by ribonuclease increases markedly the streptolysin-inducing activity of certain preparations of rib ...194818873865
absolute reaction kinetics of tobacco mosaic virus and a proposed theory of denaturation. 194818886186
immunochemical studies on tobacco mosaic virus; the serological relationship to the aucuba and j14d1 strains. 194818886535
the thermal denaturation of tobacco mosaic virus in relation to hydrostatic pressure. 194818891777
the effect of infection with tobacco-mosaic virus on the levels of nitrogen, phosphorus, protease, and pectase in tobacco leaves and on their response to fertilizers. 194816748358
electron micrographic observations of tobacco mosaic virus in crude, undiluted plant juice. 194917782717
the effect of washing frozen mosaic leaves on the length of tobacco mosaic virus particles. 194918108890
the hydration, size and shape of tobacco mosaic virus. 194918112063
viscosity and sedimentation studies on tobacco mosaic virus. 194918112152
the effect of glycerine and aniline on tobacco mosaic virus infectivity. 194918126568
amino acids in tobacco mosaic virus. 194918141654
electron microscopic and electrophoretic study of two strains of tobacco mosaic virus. 194918146816
the reaction of tobacco mosaic virus with formaldehyde; electrophoretic studies. 194918147463
the proteins of green leaves: evidence of the formation of tobacco mosaic virus protein at the expense of a main protein component in tobacco leaf cytoplasm. 194918148022
the effect of washing frozen mosaic leaves on the length of tobacco mosaic virus particles. 194916561641
on the mutation of the tobacco mosaic virus.experiments on x-ray-induced mutations of the tobacco mosaic virus (gowen) are analyzed on the basis of the ionization theory. the size of the volume within which the primary process of mutation develops is calculated on the basis of three alternative assumptions; viz., (1) that this volume consists of protein, (2) that it is nucleic acid, (3) that it is phosphorus. it is found that the volume calculated under assumption (1) is identical with the hexagonal cell unit which bernal and fankuchen fo ...194915392565
analyses of spontaneous and induced mutations of the tobacco mosaic virus. 194915394465
the effect of ph on the linear aggregation of tobacco mosaic virus. 194915398082
the interaction of tobacco mosaic virus and of its degradation products with dyes. 194915400369
the acceleration of the thermal denaturation of tobacco mosaic virus by urethan at normal and increased pressure. 194915405720
the influence of buffer composition, ph and aggregation on the thermal denaturation of tobacco mosaic virus. 194915405723
visualization of tobacco mosaic virus within infected cells. 195015409474
the ultraviolet light and photosensitized inactivation of tobacco mosaic virus.the quantum yield for the inactivation of tobacco mosaic virus has been determined at 253.7 mmicro and found to be 4.3 x 10(-6). the possible significance of the observed one-hit process of inactivation has been discussed in terms of the kinetics and the rupture of model substances including nucleic acid. the ultraviolet light inactivation, which proceeds independent of oxygen, occurs without change in physicochemical properties, with the possible exception of an enhanced sensitivity to thermal ...195015409511
immunochemical studies on tobacco mosaic virus. vi. the effect of papain on the antibody-antigen complex. 195015412250
[comparison between the extraction of the tobacco mosaic virus by mechanical means and by the action of the enzymes of the digestive tract of the snail]. 195015413823
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