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bait bases for mastomys natalensis smith 1834: a murid of public health interest in africa.mastomys natalensis is widely distributed in the whole of africa and is a reservoir of important zoonoses including plague. in order to control this species efficiently using rodenticides, tests were carried out to find the most preferred cereal and bait additives to form a suitable bait base. investigations were based on food choice tests in caged animals. among the cereals tested, rice was significantly preferred (p=0.01) followed by wheat, sorghum and maize. of the additives tested, both sexe ...012160425
plague in africa from 1935 to 1949; a survey of wild rodents in african territories.the history of plague in africa during the period 1935-49 is reviewed. much of the information derives from a questionnaire sent to all african territories in 1950. the annual incidence of plague in africa declined, particularly from 1946 onwards. in 1949, under 400 cases were reported, as compared with over 6,000 in 1935. by the end of 1949, plague was still active in the belgian congo, kenya and tanganyika, madagascar, and southern africa. no cases were reported from egypt, tunisia, algeria, m ...195313115987
spontaneous carcinoma of the glandular stomach in a laboratory stock of rattus (mastomys) natalensis. 195513281621
spontaneous carcinoma of the glandular stomach in rattus (mastomys) natalensis, an african rodent. 195713499792
a note of infection of the multimammate rat, rattus (mastomys) natalensis erythroieucus with plasmodium berghei. 195813581637
carcinomas of the glandular stomach and hepatomas in rattus (mastomys) natalensis infected with bilharzia mansoni. 195913649450
production of tumours in rattus (mastomys) natalensis by polyoma virus. 196014435664
intranuclear inclusion in rattus (mastomys) natalensis infected with rat virus. 196114489658
the multimammate mouse rattus (mastomys) natalensis: a species for the laboratory investigation of cancer of the glandular stomach. 196113730370
papillary ependymomas produced in rattus (mastomys) natalensis inoculated with vacuolating virus (sv40). 196213972899
adenocarcinoma and proliferative hyperplasia of the prostate gland in female rattus (mastomys) natalensis. 19654157483
the susceptibility of rodents to schistosome infection, with special reference to schistosoma haematobium.in this investigation the susceptibility of several species of rodents-praomys (mastomys) natalensis, saccostomus campestris, arvicanthus niloticus, aethomys chrysophilus, tatera brantsi and the white mouse (saimr 200 strain)-to schistosoma haematobium was determined and the pathology studied. from the results it is clear that these rodents are susceptible to infection with schistosoma haematobium. for various reasons, notably adaptability to laboratory conditions, the most suitable as laborator ...19665297005
fine structure of the gastric mucosa of the cancer-producing african rodent, rattus (mastomys) natalensis. i. normal general structure. 19665925779
degenerative joint disease in praomys (mastomys) natalensis. 19676023697
induction of a high incidence of damage to the x chromosomes of rattus (mastomys) natalensis by base analogues, viruses, and carcinogens. 19674299043
neoplastic and non-neoplastic renal disease in praomys (mastomys) natalensis. 19676030033
concerning the incidence of "spontaneous" stomach cancer in praomys (mastomys) natalensis. 19685673570
thymomas and thymic hyperplasia in praomys (mastomys) natalensis. concomitant myositis, myocarditis, and sialodacryoadenitis. 19685660267
pathological analysis of spontaneous carcinogenesis in glandular stomach of praomys (mastomys) natalensis. 19685666251
susceptibility of praomys (mastomys) natalensis to the murine sarcoma virus-harvey (msv-h). 19684302086
the carinogenicity of n-hydroxy-n-2-fluorenyl-acetamide and the matabolism of n-2-fluorenyl-acetamide in praomis (mastomys) natalensis. 19684303104
spontaneous thymoma, polymyositis, and serum-autoantibodies to striated muscle in the rodent, subgenus praomys (mastomys) natalensis. similarities to thymoma with myasthenia gravis in man. 19684171846
karyologic and autoradiographic studies of the chromosomes of rattus (mastomys) natalensis. 19685653740
[on the host-parasite relationship in mastomys natalensis (smith, 1834)]. 19685719585
some developments in techniques for the study of the rodent filarial parasite litomosoides carinii. i. a preliminary comparison of the host effciency of the multimammate rat, praomys (mastomys) natalensis, with that of the cotton rat, sigmodon hispidus. 19685729256
some developments in techniques for the study of the rodent filarial parasite litomosoides carinii. ii. a quantitative method for the culture of the mite ornithonyssus bacoti and for the routine transmission of litomosoides carinii to praomys (mastomys) natalensis. 19685729257
[infection experiments with the cotton rat filaria litomosoides carinii in mastomys natalensis (smith, 1834)]. 19685746888
[experimental infections with intestinal nematodes, cestodes and trematodes in mastomys natalensis (smith, 1834)]. 19685746894
experimental infection of the african multimammate mastomys, rattus (mastomys) natalensis, with the minute stomach worm trichostrongylus axei. 19685757724
hematopoietic neoplasms and related conditions in praomys (mastomys) natalensis. 19694885322
malignant argyrophilic gastric carcinoids of praomys (mastomys) natalensis.cells of carcinoid tumors which arise in the glandular stomach of old male and female praomys (mastomys) natalensis contain argyrophil granules when tissues fixed in formalin are colored with solutions of silver salts. the carcinoids metastasize in about 25 percent of cases, and are transplantable to other mastomys. tumor-bearing animals may show gastric and duodenal ulcers and multiple endocrine adenomas.19695303997
prostatic hyperplasia and neoplasia in female praomys (mastomys) natalensis. 19704098904
histamine production by transplantable argyrophilic gastric carcinoid of praomys (mastomys) natalensis.a transplantable argyrophilic gastric carcinoid of praomys (mastomys) natalensis contained appreciable amounts of histamine. dialyzed, microsome-free supernatant of tumor tissue produced definite amounts of histamine in the presence of l-histidine and pyridoxal phosphate. these findings may relate to hypersecretion of gastric acid and formation of multiple ulcers in the stomach and duodenum of mastomys bearing carcinoids.19705460070
response of adult mastomys (praomys natalensis) to subcutaneous injection of n-nitrosodimethylamine. 19704320041
histological and immunohistochemical studies on spontaneous renal lesions of praomys (mastomys) natalensis. 19704928077
[precipitating antibodies in the serum of mastomys natalensis in the course of litomosoides carinii infection]. 19704993040
[the albumin-globulin ratio in the serum of mastomys natalensis (smith, 1834) in the coruse of infection with litomosoides carinii]. 19705436819
the efficacy of various anthelmintics against the parasitic larval stages of ancylostoma caninum in mastomys natalensis. 19705485196
chemotherapeutic studies on experimental schistosoma mansoni infection of mastomys natalensis.comparative chemotherapeutic studies on various well known or newly developed schistosomicidal agents have been carried out in mastomys natalensis experimentally infected with schistosoma mansoni. hycanthone, lucanthone, niridazole, mirasan, the experimental compounds hoe s616, hoe s683, hoe s688, and hoe s201, tartar emetic, stibophen, and stibocaptate acid have shown marked activity when administered in standard daily dosages for 5 consecutive days. dehydroemetine and bis (p-rosaniline pamoate ...19715317444
chemotherapeutic studies on litomosoides carinii infection of mastomys natalensis. 1. the filaricidal action of 2,6-bis-benzimidazoles.the antifilarial action of 2-[2-(4-hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazyl) benzimidazole (hoe 33258) was investigated in mastomys natalensis infected with litomosoides carinii. the subcutaneous administration of hoe 33258 in a single daily dose for 5 consecutive days, or at other intervals, produced, depending on the dosage, a rapid reduction in the number of microfilariae in the circulating blood. the reduction amounted to more than 90% within 7-14 days after the treatment was ...19715317445
chemotherapeutic studies on litomosoides carinii infection of mastomys natalensis. 2. the activity of drugs against microfilariae.comparative investigations of the chemotherapeutic activity of various filaricidal compounds and other anthelmintics were made with litomosoides carinii infections in mastomys natalensis, special consideration being given to the microfilaricidal activity of the compounds. diethylcarbamazine, cyclohexanecarboxylic acid-n-methylpiperazide citrate (hoe 28637a), tetrahydropyranecarboxylic acid-n-methylpiperazide citrate (hoe 29691a), (+/-)-tetramisole, (-)-tetramisole (levamisole), and metrifonate p ...19715317446
chemotherapeutic studies on litomosoides carinii infection of mastomys natalensis. 3. the activity of drugs against adult parasites.comparative studies of the chemotherapeutic activity of various filaricides were carried out and the results in litomosoides carinii infections of mastomys natalensis were analysed with special reference to macrofilaricidal activity. the administration of suramin in daily subcutaneous doses of 40 mg per kg of body weight for 5 consecutive days showed marked activity against macrofilariae and killed the adult worms within 6 weeks after the beginning of treatment. the microfilarial count of the ci ...19715317447
[experimental infection in mastomys natalensis (smith 1834) with trypanosoma species of the lewisi-congolense and brucei-evansi groups]. 19714946451
histidine decarboxylase in the transplantable argyrophilic gastric carcinoid of praomys (mastomys) natalensis. 19714329805
[comparison of the influence of mixed grain food and food pellets on reproduction and growth of mastomys natalensis (smith, 1834)]. 19715096329
tumors of the testes and seminal vesicles in praomys (mastomys) natalensis. 19724650201
[cellular composition of the bone marrow of mastomys natalensis]. 19725021992
the development of ultrastructural glomerular alterations in praomys (mastomys) natalensis. an electron microscopic study. 19724336536
[normal values of various enzymes in the serum of mastomys natalensis (smith 1834)]. 19725036387
immunological and clinical-chemical investigations on blood, urine, and kidney in aging praomys (mastomys) natalensis with spontaneous glomerulonephritis. 19724122173
microbodies in experimentally altered cells. ix. the fate of microbodies.male rats were given 0.25% cpib (ethyl chlorophenoxyisobutyrate) for 4 weeks at which time their liver cells showed the typical increase in number of microbodies (peroxisomes). during the first week after withdrawal of cpib and simultaneous injection of allylisopropylacetamide (aia), an inhibitor of catalase synthesis, the microbody matrix, in peroxidase preparations, showed marked decrease in electron opacity. in liver cells of rats from which cpib was withdrawn but which were not given aia, th ...19724338207
[pathophysiological and toxicological aspects of schistosoma mansoni infection in mastomys natalensis under treatment with hycanthone]. 19734360332
haemoglobin of mastomys natalensis (rattus natalensis). earlier observations on starch gel electrophoretic pattern, column chromatographic fractionation and polypeptide chains separation. 19734747094
[litomosoides carinii infection of mastomys natalensis: alterations of haematological parameters (author's transl)]. 19734770091
[pseudocholinesterases' activity in the kidney. comparative study in the rat and in mastomys (praomys natalensis)]. 19734794624
fluorescence and electron microscopic histochemistry of endocrine-like cells in gastric mucosa and argyrophil tumor of praomys (mastomys) natalensis. analysis of 5-hydroxytryptamine, histamine, histidine decarboxylase, and aromatic amino acid decarboxylase. 19734770333
ultrastructure of endocrine cells and argyrophil carcinoids of the stomach of praomys (mastomys) natalensis. 19734736894
[infectious keratoacanthomas of the epidermis in praomys (mastomys) natalensis]. 19734709365
histamine formation in spontaneous gastric carcinoids of praomys (mastomys) natalensis. 19744852273
a renal tumour of the nephroblastoma type in praomys (mastomys) natalensis. 19744366011
[litomosoides carinii infection of mastomys natalensis: serological studies with the complement fixation and the indirect haemagglutination test in the course of infection (author's transl)]. 19744833626
lassa virus isolation from mastomys natalensis rodents during an epidemic in sierra leone.lassa fever is a severe febrile illness of man, first recognized in west africa in 1969. during an epidemic in sierra leone, lassa virus was isolated for the first time from wild rodents of mastomys natalensis. a high prevalence of infected mastomys was found in houses occupied by patients with lassa fever. the data presented provide the first demonstration of an extra-human cycle of lassa virus transmission and suggest that rodent control may be an effective method of limiting the disease.19744833828
[litomosoides carinii infection of mastomys natalensis: relationship between microfilaraemia and adult worm population (author's transl)]. 19744836671
[pathophysiological investigations of schistosoma mansoni infection in mastomys natalensis under chemotherapy with a nitrovinylfuran derivative (sq 18.506) (author's transl)]. 19744839002
notes on the host-parasite relationship during infection of praomys (mastomys) natalensis with the filarial parasite litomosoides carinii. 19744853378
proceedings: mastomys natalensis as a host for dipetalonema viteae. 19744856425
chemotherapeutic studies on litomosoides carinii infection of mastomys natalensis. 4. the prophylactic and suppressive activity of suramin. 19744857965
[capillaria hepatica infection of mastomys natalensis: alterations of enzyme activities in serum (author's transl)]. 19744152645
[experimental study of the activity of the sulphamethoxypyrazine (longum equals kelfizina) with pyrimethamine (daraprim) on the cysts development phase of toxoplasma gondii in mastomys natalensis. further contribution to experimental chemotherapy of toxoplasmosis (author's transl)]. 19744152678
induction of forestomach, duodenal and liver tumors in praomys (mastomys) natalensis by oral or intragastric administration of n-methyl-n'-nitro-n-nitrosoguanidine. 1975171764
the structure of rodent faunas associated with arenaviral infections.the biogeographical examination of rodent faunas associated with arenaviruses reveals two distinct patterns. lymphocytic choriomeningitis (lcm) virus is associated primarily with a single murid species, mus musculus, although it is also known to cause laboratory infections in other species. on the other hand, the arenaviruses from the western hemisphere are associated exclusively with a large and diverse group of cricetid rodents. studies to date, although limited, have not demonstrated their as ...1975182403
lassa fever: review of epidemiology and epizootiology.the basic ecology of lassa fever appears to involve enzootic transmission of virus in commensal populations of a single murine species, mastomys natalensis. virus may spill over from the rodent cycle to man by various routes. secondary spread between humans may occur within domiciliary groups, and persons infected within the community who develop clinical disease may introduce the virus into hospital and begin a cycle of nosocomial infection.between 1969, when lassa fever was first described, an ...1975782738
comparative pathology of lassa virus infection in monkeys, guinea-pigs, and mastomys natalensis.experimental lassa virus infections of squirrel monkeys, guinea-pigs, and the african multimammate rat, mastomys natalensis, were studied virologically and pathologically. in the monkeys, early viral lymphoreticulotropism, hepatotropism, nephrotropism, and viraemia were noted. at the time of death, viral titres in nearly all target organs were associated with necrotic changes: splenic lymphoid necrosis, renal tubular necrosis, myocarditis, arteritis, and hepatocytic regeneration. in convalescent ...1975821625
recent isolations of lassa virus from nigerian rodents.rodents were trapped in the benue-plateau and north-eastern states of nigeria where lassa fever had been reported in previous years. eight lassa virus strains were isolated from tissues and blood of rodents identified in the field as being of 3 different species: mastomys natalensis, rattus rattus, and mus minutoides. all the infected rodents were collected in village habitats. these isolations indicate the presence of lassa virus in wild rodents in nigeria during periods when no human infection ...19751085216
the ecology of praomys (mastomys) natalensis in southern africa.the only non-human host of lassa virus so far identified is the multimammate mouse, praomys (mastomys) natalensis, but its precise role in the natural lassa fever cycle remains to be determined. this species is also an important link in the plague cycle in southern africa and is one of the commonest rodents of africa. it is a prolific breeder and can be kept and bred easily in captivity. it is thus an excellent laboratory animal, although it needs to be handled with care because it is aggressive ...19751085218
the biology, behaviour, and ecology of mastomys natalensis in southern africa.the multimammate mouse, mastomys natalensis, is the most widespread and common rodent in africa south of the sahara. it is an ideal carrier of normally non-human diseases to the domestic environment, not only because of its semi-commensal habit but also because of a combination of other behavioural and ecological factors. of these, the most important is an exceptionally high propagation rate.19751085219
spontaneous diseases in a closed colony of praomys (mastomys) natalensis.in comparison with other rodents, the mastomys is unique as regards the patterns of neoplastic and non-neoplastic diseases that it develops, some of which may constitute suitable animal models for corresponding diseases of man. among the spontaneous diseases commonly encountered in necropsies of 600 mastomys maintained in a closed colony were: (1) degenerative joint disease of diarthroses and interventricular disks, which develops regularly in the second year of life; (2) renal disease, a type o ...19751085220
lassa virus infection in mastomys natalensis in sierra leone. gross and microscopic findings in infected and uninfected animals.pathological examinations of 28 wild-caught mastomys natalensis from sierra leone, 14 of which were positive for lassa virus by tissue culture, are reported. the high frequency of neoplastic and degenerative diseases observed among older animals in closed colonies of m. natalensis were not observed in the wild animals studied. this is probably a reflection of the age distribution of the study population, since the life expectancy of wild mastomys is less than a year. inflammatory lesions were no ...19751085221
problems of rodent control in rural tropical areas.rodent control strategies, techniques, and research needs in rural tropical environments are reviewed and discussed with special reference to mastomys natalensis, the possible reservoir of lassa fever in west africa.public health rodent problems are far more serious and widespread in rural tropical areas than in developed countries. in the latter, only the commensal rodents constitute a major problem, whereas in rural tropical areas, native semidomestic species also serve as disease reservoirs a ...19751085222
evaluation of demographic parameters of native rodent populations and implications for control.the ecology of the multimammate mouse ,mastomys natalensis, is reviewed and approximations are derived for the parameters governing population growth. by means of computer simulation, the relative importance of the timing of reproduction, the age class distribution or age structure of the population, the competition between mastomys and rattus, and the interaction with a predator are evaluated. although each of these demographic or ecological factors modifies the fate of the mastomys population, ...19751085223
[chemotherapeutic studies on litomosoides carinii infection of mastomys natalensis. 5. alterations of haematological parameters after the administration of filaricidal compounds (author's transl)].the peripheral blood picture of multimammate rats (mastomys natalensis) infected with litomosoides carinii was studied. changes were followed in patent infections from 64 to 176 days after infection in animals treated with diethylcarbamazine (5 x 100 mg/kg per os), hoe 258 v (5 x 10 mg/kg subcutaneously), suramin (5 x 40 mg/kg subcutaneously) and with a combined treatment of diethylcarbamazine and suramin. in addition, haematological changes were followed in non-infected animals treated with sur ...19751096385
chemotherapeutic studies on litomosoides carinii infection of mastomys natalensis. 6. the filaricidal activity of organophosphorus compounds.several organophosphorus compounds have been evaluated for their efficacy against micro- and macrofilariae in experimental investigations on litomosoides carinii infection in the multimammate rat mastomys natalensis. the anthelmintic haloxon proved to be the most effective compound with high activity against microfilariae and a favourable chemotherapeutic range. the organophosphates fenthion, dursban, metrifonate, coumaphos, crufomate and naphthalophos also showed pronounced microfilaricidal act ...19751189030
["keratoacanthomas" in mastomys natalensis (author's transl)].54 tumors of mastomys natalensis (gra giessen), described in the literature as "keratoacanthomas" were investigated by light and electron microscopy. they are induced by a virus of the papova group. their histogenesis and their course are very different from human keratoacanthoma. the results reveal problems related to experimental animal tumour models and the similarities of different malignancies in the nomenclatures of several disciplines.19751211973
mastomys natalensis as an experimental host for brugia malaye subperiodic.infective larvae of brugia malayi subperiodic obtained by dissection of infected aedes togoi were injected subcutaneously into the scrotal region of mastomys natalensis. from altogether 58 infected male m. natalensis 81% showed consistently or intermittently detectable microfilaraemia, whereas in 19% of the animals no microfilaraemia could be detected at any stage. the mean prepatent period was 136 days; the microfilarial density varied from 1 to 535 per 20 c. mm blood. in those animlas with con ...19751221502
electron microscope study on endocrine cells and tumor cells in the glandular stomach of praomys (mastomys) natalensis.endocrine cells in the normal glandular stomach and gastric carcinoids of mastomys were observed by electron microscopy and at least five types of endocrine cells, ec, g, d-like, r (round-granule) and ecl cells were identified. of these, four types excepting g cells were recognized in the fundic mucosa. characteristic in mastomys was a scarcity of endocrine cells in the fundic mucosa, where ecl and r cells were predominant types. silver impregnation methods including sevier-munger's argyrophil r ...19751203028
[occupationally induced sensitization of respiratory airways by animal-hair and animal-dust].an occupational sensitization of the respiratory tract caused by hair and dust of laboratory animals (mastomys natalensis) was reported in 3 persons. intracutaneous tests confirmed the relationship between the professional activity and the clinical symptoms of an inhalation allergy. the very pronounced reaction to different dust extracts and the special conditions of exposure suggest an occupational sensitization to the dust of laboratory animals.19751200957
identification of a prostate in female praomys (mastomys) natalensis using 3-h steroids.the female of the species praomys (mastomys) natalensis has a ventral prostate similar both in position and in histological appearance to the ventral lobe of the male prostate. the hormonal uptake of this female prostate has been investigated using (3-h) testosterone and (3-h) oestradiol. the results showed that the uptake of these steroid hormones by the prostate was identically to our findings in the male prostate. the potential value of a female prostate in prostatic research is discussed.19751131500
patterns of neoplastic and nonneoplastic diseases of praomys (mastomys) natalensis. 1975796913
spontaneous tumors and atypical proliferation of pancreatic acinar cells in mastomys (praomys) natalensis.in 17 of 90 untreated 2-year-old mastomys (praomys) natalensis, an acinar cell tumor was observed, and atypical acinar proliferation was noted in 30. the lesions, either neoplastic or proliferative, consisted of large polygonal cells with prominent nucleili in the enlarged hyperchromatic nuclei. the cytopalsms of these cells were polychromatic and were characterized by a central eosinophilic granular area and a peripheral basophilic fibrillar zone around an eccentric nucleus. the differntiated c ...19761003562
an electrophoretic polymorphism in the serum transferrins of praomys (mastomys) natalensis.three serum transferrin phenotypes of praomys (mastomys) natalensis, and african rodent having a high incidence of many varieties of spontaneous neoplasms, were detected by electrophoresis and autoradiography. on electrophoresis, transferrin of trf-k was found to be a protein that migrates slowly toward the cathode, whereas that of trf-m migrates rapidly. trf-km is a heterozygous phenotype of the above two. progeny testing demonstrated that these three serum transferrin phenotypes in mastomys ar ...19761008800
[pathological anatomy and histology of spontaneous, epithelial skin tumors in mastomys natalensis]. 1976822652
[induction of epidermal tumor growth in the skin of mastomys natalensis by transfer of virus-containing tumor tissue from a squamous cell carcinoma]. 19761266439
the homocytotropic and hemagglutinating antibody responses to brugia pahangi infection in the multimammate rat (mastomys natalensis).homocytotropic and hemagglutinating antibody responses were followed in multimammate rate (mastomys natalensis) infected with brugia pahangi. homocytotropic antibodies were detected by both active and passive cutaneous anaphylaxis using an antigen prepared from dirofilaria immitis. the homocytotropic antibody response was first evident at 3 weeks after infection and increased progressively until after patency. it then waned gradually and was absent at 33 weeks after infection (or 20 weeks after ...19761259087
[capillaria hepatica infection of mastomys natalensis: on the development, egg production and host reaction (author's transl)].studies on the development and egg production of capillaria hepatica and on the macroscopically visible alterations of the liver and spleen of the host were carried out in experimentally infected mastomys natalensis. following the oral administration of infective eggs the first stage larvae hatched in the caecum of fasting and fed animals after about 8 and 15 hours respectively. the prepatency could be found with 20 days. the dynamics and duration of egg production of the parasite proved to be d ...19761266288
natural resistance of an african rodent praomys (mastomys) natalensis to rabies infection.praomys (mastomys) natalensis, the multimammate mouse, proved resistant to the intracerebral and peripheral infection with rabies virus of serotype 1, which is found world-wide. it is, however, fully susceptible to the other serotypes of this virus group, which to-date have only been found on the african continent. resistance develops between the third and twenty-first day after birth. in the brain of the resistant animal the inoculated virus multiplies to a low degree and the animal does not de ...1976952444
absence of vitamin b12-binding proteins in the histamine-containing gastric carcinoid in praomys (mastomys) natalensis.the transplantable argyrophilic gastric carcinoids producing histamine found in praomys (mastomys) natalensis contained no significant amount of vitamin b12-binding proteins. it was also demonstrated that the concentration of vitamin b12-binding proteins in glandular stomach of mastomys was much lower than those in the same tissues of the rat or mouse.19761001869
fate of litomosoides carinii adults transplanted into the pleural or peritoneal cavity of infected and naive multimammate rats (mastomys natalensis).in each of 4 experiments, 58 multimammate rats (mastomys natalensis) were subdivided into 5 groups. thirty-four rats were infected with litomosoides carinii and infections were allowed to become patent. ten days after patency adult worms were surgically transferred from donor rats to each of 1 group of infected rats and 1 group of naive rats. groups of infected and naive rats served as controls. transfers were made either intrapleurally or intraperitoneally. samples of blood and tissues were tak ...19761003278
lassa fever (arenaviruses) as a public health problem.two "new" virus infections, marburg and lassa fever, now constitute diseases of public health importance in several countries of africa, especially west africa. lassa fever has an insidious onset, is initially difficult to diagnose, has "nonspecific" clinical symptoms which have been confused with yellow fever and typhoid, shows evidence of persistent infection, is tremendously contagious, has a high mortality rate, and in particular exhibits unusual nosocomial propensity. it has also been shown ...19761026322
uptake and distribution of 3h testosterone in tissues of male praomys (mastomys) natalensis: an in vivo and in vitro study on the prostate.following the administration of labelled testosterone into 4-6 month old intact, or 24 h orchiectomized praomys (mastomys) natalensis, the uptake of radioactivity by the prostate and other tissues was measured at different intervals. two hours after the injection of the hormone, the concentration of radioactivity in the prostate was significantly higher than in most of the other organs, but less than that of the liver and kidney. most of the radioactivity taken up by the liver and kidney disappe ...1976134485
intracutaneous cornifying epithelioma ("keratoacanthoma") of dogs and keratoacanthoma of man.the intracutaneous cornifying epithelioma ("keratoacanthoma") of dogs was compared with keratoacanthoma of man based on findings in the literature and in house studies. the two tumors differ at the following points: epithelium of origin, rate of growth, infiltration, spontaneous involution, breed predisposition (norwegian elkhound, generalized form), occurrence in dogs at a younger or middle age. the development of this tumor in dogs seems to be comparable with the development of so-called kerat ...1977858252
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