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genetic integration of molar cusp size variation in baboons.many studies of primate diversity and evolution rely on dental morphology for insight into diet, behavior, and phylogenetic relationships. consequently, variation in molar cusp size has increasingly become a phenotype of interest. in 2007 we published a quantitative genetic analysis of mandibular molar cusp size variation in baboons. those results provided more questions than answers, as the pattern of genetic integration did not fit predictions from odontogenesis. to follow up, we expanded our ...020034010
the arnold-chiari malformation in a sacred baboon (papio hamadryas). 195513295936
studies on spontaneous primary encephalitides in the monkey. i. a polio-encephalitis with predilection for the brain stem in the baboon (papio hamadryas). 195913642086
studies on spontaneous primary encephalitides in the monkey. ii. encephalitis with a cortico-striate predilection in the baboon (papio hamadryas). 195913642087
[on the "hybrid" antigen in monkeys (theropithecus gelada x papio hamadryas)]. 196314077733
[roentgenological changes in the skeleton of sacred baboons after prolonged gamma-irradiation]. 19684984501
[steroid metabolism in primates. 8. corticosteroids in the adrenal venous blood of the baboon (papio hamadryas)]. 19695376365
a study of haemolytic disease of the foetus and the newborn occurring in hamadryas baboons under natural conditions. 19694981657
the velocity of the pulse wave distribution and arterial piesography in adult hamadryas baboons and rhesus monkeys. 19694981656
[steroid metabolism in primates. iv. isolation of aldosterone from adrenal venous blood of macacus rhesus, papio hamadryas, cercopithecus aethiops and erythrocebus patas]. 19694982968
[steroid metabolism in primates. vi. isolation of progesterone and pregnenolone from adrenal venous blood of macacus rhesus, papio hamadryas, cercepithecus aethiops and erythrocebus patas]. 19694982969
the cape western baboon in organ allotransplantation. 19705000235
[some data on the nature of cortisol metabolism in macaca rhesus monkeys and hamadryas baboons]. 19714330564
[electric activity of the cortex and deep structures of the brain in aroused hamadryas baboons]. 19714997570
[steroid metabolism in primates. xiv. influence of long-term ovosiston therapy on the secretion of adrenal vein blood steroids in papio hamadryas]. 19724121482
[changes in the skeleton of hamadryas baboons during prolonged administration of excess sodium chloride]. 19724624906
the breeding of hamadryas baboons at the sukhumi primate centre. 19724627308
[steroid metabolism in primates. xii. isolation of corticosterone, tetrahydro-corticosterone, tetrahydro-11-dehydro-corticosterone, 11-deoxy-cortisol and tetrahydro-11-deoxy-cortisol from the urine of macacus rhesus and papio hamadryas]. 19724624286
rate of secretion of corticosteroids in hamadryas baboons under normal conditions and following lengthy administration of chlormadinone acetate and mestranol. 19724116113
[experimental prenatal treatment of hemolytic disease of the newborn in monkeys (papio hamadryas)]. 19724623476
comparative features of the reproductive biology of hamadryas baboons (papio hamadryas), grivet monkeys (cercopithecus aethiops) and rhesus monkeys (macaca mulatta). 19724627306
the use of hamadryas baboons for the study of the immunologic aspects of human reproduction. 19724627311
[phasic analysis of cardiac activity in rhesus monkeys and hamadryas baboons]. 19724624905
the epidemiologic and genetic aspects of an outbreak of leukemia among hamadryas baboons of the sukhumi monkey colony. 19734360160
a comparison of anubis baboons, hamadryas baboons and their hybrids at a species border in ethiopia. 19734201907
cooperative tool use by captive hamadryas baboons.a bonded pair of hamadryas baboons developed cooperative tool use without training. the male could get food with the tool but first had to get the tool from an adjoining cage which he could not enter. the female learned to give him the tool. cooperation was temporarily disrupted by the terminal phase of the female's estrous inflation.197317739727
[similarities and differences in the sleep of 2 baboons, papio hamadryas and papio papio]. 19734124615
[ecg in baboons (papio hamadryas)]. 19734200469
[steroid metabolism in primates. xv. excretion of c19 and c21 steroids in the urine of baboons (papio hamadryas) after long-term treatment with a combination of mestranol-chlormadinone acetate].the urinary excretion of c21- and c19-steroids was investigated in female babons (papio hamadryas) treated with the ovulation inhibitor ovosiston (mestranol + chlormadinone-acetate), in comparison with an untreated control group urinary c21-steroid excretion was not significantly altered by ovosiston. 17-ketosteroids were decreased, predominantly 11-oxygenated compounds.19744143128
[differential effects of p-chlorophenylalanine on sleep in primates, papio papio and papio hamadryas]. 19744135023
establishment of continuous cell lines from leukocytes culture of a hamadryas baboon with leukosis-reticulosis. 19744373669
[comparative characteristics of 2 c-type oncornaviruses isolated from hamadryas baboons with hemoblastosis]. 1975173511
[generic characteristics and specific characteristics of the ponto-geniculo-occipital spike activity (pgo) in 2 baboons, papio hamadryas and papio papio]. 1975167907
the establishment of continuous lymphoblastoid suspension cell cultures from hematopoietic organs of baboon (papio hamadryas) with malignant lymphoma.two continuous suspension lymphoblastoid cell cultures designated as spg-1 and kmpg-1 have been established from the bone marrow and spleen cells of the hamadryas baboon no. 9386 with malignant lymphoma. virus particles morphologically characterized as herpes-like have been revealed in kmph-1 and spg-1 cultures in 2-10% of cells. the paper describes the establishment of these suspension cultures.1975823042
[steroid metabolism in primates. xvi. secretion of corticosteroids in the baboon papio hamadryas during chronic administration of sodium chloride].the adrenal steroid secretion was investigated in male baboons (papio hamadryas) treated for a long time with sodium chloride, in comparison to an untreated control group. in animals treated with nacl, the secretion of progesterone, 17alpha-hydroxyprogesterone, 11-deoxycortisol, aldosterone and corticosterone was decreased, while cortisone, pregnenolone, 7-keto-cholesterol, 7-keto-dhea, dhea and adrenosterone were increased.1975125195
[differential staining of hamadryas baboon chromosomes with romanovsky-giemsa dye (g-discs)].the pattern of g-discs in the chromosomes of baboon (papio hamadryas) was studied after staining by means of asg method. on the basis of these data all the 20 pairs of autosomes and sex chromosomes were identified. according to the distinctness of the discs all the chromosomes were classified into 3 groups: well differentiated, faintly differentiated and moderately differentiated. the most distinct pattern of discs was obtained in slightly spiralized chromosomes. dimorphism of the disc pattern i ...197556287
[chromosome identification in macaca arctoides based on study of the differential staining pattern (g-discs). comparison with papio hamadryas g-discs].linear chromosome differentiation pattern of macaca arctoides was studied using the romanovsky-gimsa stain (g-banding). the possibility of the identification of all chromosome pairs according to these data is demonstrated. the phenomenon of the irregular intercellular and chromosome differentiation is found out and a suggestion is made about its relation to a real mosaic functional activity of cell genomes. a great similarity in linear chromosome differentiation for 2 from 42 studied chromosome ...197556288
[identification of simian chromosomes by the differential staining method with romanovskii-giemza stain. ii. papio hamadryas].by means of differential staining with the romanovsky - gimsa dye the distribution of g-bands was studied in chromosomes of bone marrow cells and of cultured peripheral blood lymphocytes in papio hamadryas. all the homologous chromosome pairs were identified. it was shown, as compared papio hamadryas karyotypes with that of macaca mulatta, that patterns of most chromosomes differentiation were similar. certain differences between these species were observed in the character of differentiation of ...197560271
polymorphism of the ca-i locus of carbonic anhydrase in baboon.polymorphism of erythrocytic carbonic anhydrase was studied by means of the usual technique of starch gel electrophoresis in papio papio, papio hamadryas, papio cynocephalus and papio anubis. in a sample containing both papio cynocephalus and papio anubis, examples of the homozygote ca-ib/ca-ib were found. a study of parental transmission established the ca-ib allelic form.1975804560
[identification of simian chromosomes by a method of differential staining with romanovskii--giemsa solution. ii. papio hamadryas].by means of differential staining wiyh the romanovsky-- gimsa dye the distribution of g-bands was studied in chromosomes of bone marrow cells and of cultured peripheral blood lymphocytes in papio hamadryas. all the homologous chromosome pairs were identified. it was shown, as compared papio hamadryas karyotoypes with that of macaca mulatta, that patterns of most chromosomes differentiation were similar. certain differences between these species were observed in the character of differentiation o ...197557902
[identification of mycoplasmas isolated from monkeys].the authors identified 15 strains of mycoplasmae isolated from papio hamadryas suffering from leukemia and from healthy macacus rhesus, a green monkey and saimiri. a study was made of their biochemical properties, antigenic properties in the reaction of growth depression with immune sera to a number of standard strains, and also the protein composition by electrophoresis in polyacrylamide gel (epag). a number of mycoplasmae were identified as a. laidlawii, m. arthritidis--campo and m. cynomolgus ...1975235821
possible ways viral leukemia spreads among the hamadryas baboons of the sukhumi monkey colony.leukemia virus transmission was studied during an outbreak of leukemia among the baboons of the sukhumi monkey colony. first, the possibility of "vertical" transmission of the virus was examined, as the papio stock in sukhumi was genetically homogeneous. "vertical" transmission of the virus from a common ancestor seems unlikely, since cases of leukemia were registered in animals descending from different families. however, there were cases of innate leukemia, when babies born from leukemic paren ...1975809037
[preparation and comparative evaluation of experimental anthrax diagnostic sera in experiments on animals].the authors present the results of studies on obtaining and comparative assessment of experimental anthrax diagnostic sera in experiments on various animals. donkeys, sheep, horses, rabbits and monkeys (papio hamadryas) were immunized with the sti-i vaccine by a single scheme. the activity of the obtained sera was tested in the diffuse precipitation reaction by the amount of the detected antibodies and the titre. the most active sera were obtained from donkeys and sheep: their titre was 5.5 and ...19751124613
[functional dimorphism in satellite chromosomes in hamadryas baboons].dimorphism of satellite chromosomes observed in bone marrow of female as well as male papio hamadryas, and in continuous cultures of the monkey haemopoetic cells is described. most frequently the observed dimorphism is expressed in different lengths of satellite arms. the structural dimorphism of satellite chromosomes seen in macaca, papio and other genera may seem to originate from different degrees of functional activity of these chromosomes. the active homologue is longer since its satellite ...19751162740
[preparation of suspension lymphoblastoid cell cultures, containing herpes-like viruses, from hematopoietic organs of hamadryas baboons with hematosarcoma]. 1975165924
the characterization of polar corticosteroids in the urine of the macaque monkey (macaca fascicularis) and the baboon (papio hamadryas).computerised gas chromatography-mass spectrometry was employed in the identification of polar corticosteroid metabolites excreted in the urine from the macaque monkey (macaca fascicularis) and the baboon (papio hamadryas). the following steroids were identified in significant amounts in the urine from both species: 3alpha,17alpha,20alpha, 21-tetrahydroxy-5beta-pregnan-11-one; 3alpha,17alpha,20beta,21-tetrahydroxy-5beta-pregnan-11-one; 5beta-pregnane-3alpha,11beta,17alpha,20alpha,21-pentol; 5beta ...19751173507
high salt intake and blood pressure in lower primates (papio hamadryas).one year of increased salt intake in monkeys elevates mean blood pressure significantly. this effect is more marked in animals exposed just after birth. in animals exposed as adults, the response in males is more pronounced than in females, mainly due to a marked increase of pulse pressure. th hypertensive response was potentiated by reduction of renal mass, which caused gfr values (in terms of body weight) to decrease compared with intact salt-fed animals, in which gfr values were elevated abov ...1976931881
hormonal changes during the menstrual cycle of the baboon (papio hamadryas).eleven unconjugated steroids were measured daily during a complete cycle in the peripheral plasma of 6 normally menstruating baboons (papio hamadryas) by means of a radioimmunoassay procedure and the levels were compared with those found previously in 17 normally menstruating women. the patterns of progesterone and 20alpha-dihydroprogesterone were very similar to those found in women throughout the entire menstrual cycle. however, the ratio of these steroids differed markedly from that found in ...1976132074
virological studies of baboon (papio hamadryas) lymphoma: isolation and characterization of foamyviruses.in accordance with a memorandum of understanding in cancer research between scientists in the ussr and the usa, virological studies were performed on two baboons from the russian colony at the institute of experimental pathology and therapy at sukhumi where several cases of leukemia have been observed over the past few years. foamyvirus isolations were made from lymphoid cells of both of these monkeys, one of which had a confirmed case of lymphoma. the isolates were similar to each other serolog ...197658063
properties of a baboon lymphotropic herpesvirus related to epstein-barr virus.three lymphoblastoid cell lines were established from splenic lymphocytes of a lymphomatous baboon (papio hamadryas) by co-cultivation of the lymphocytes with x-irradiated cells of marmoset or baboon lymphoblastoid cell cultures; the baboon splenic lymphocytes failed to grow when cultured alone. a herpesvirus, associated with each cell line, was identified by immunofluorescence, molecular hybridization and electron microscopy. antigenic comparison with epstein-barr virus (ebv) showed that the ba ...1976186420
cell surface antigens detected in cell lines established from lymphomatous papio hamadryas and macaca arctoides monkeys.cell surface antigens associated with bone marrow cell cultures from leukemic monkeys of species papio hamadryas and macacus arctoides were visualized by means of an indirect immunofluorescence method with sera from leukemic baboons. the same immune serum gave two types of immunofluorescence, depending on the origin of the target cells. fluorescence of the ring-reaction type was seen with papio hamadryas bone marrow cell cultures growing in suspension and containing the baboon herpesvirus, where ...1976185533
[demonstration by immunofluorescence of somatotropic cells and prolactin cells in the monkeys erythrocebus patas, cercopithecus aethiops and papio hamadryas].using antibodies against human sth and ovine prolactine, it is possible to identify somatotropic and prolactin cells in the pituitary anterior lobe of three species of monkeys: erythrocebus patas, cercopithecus aethiops and papio hamadryas. the somatotropic cells are numerous in both adult and infant male or female monkeys, especially in the lateral lobes of the pituitary gland. the prolactin cells can be distinguished in all pituitaries studied, regardless age or sex; indeed there are more nume ...1976140737
plasma levels of unconjugated steroids in male baboons (papio hamadryas) and rhesus monkeys (macaca mulatta).in an attempt to find suitable animal models to aid in the study of the reproductive processes of the human male, plasma levels of unconjugated pregnenolone, 17-hydroxypregnenolone, dehydroepiandrosterone, 20alpha-dihydroprogesterone, 17-hydroxyprogesterone, androstenedione, testosterone, dihydrotestosterone, oestrone and oestradiol were measured in 18 male baboons and 10 male rhesus monkeys and the steroid levels were compared with those previously established in normospermic, middle-aged men. ...1976132836
gastric haemorrhage and perforation caused by a trichobezoar in a baboon (papio hamadryas).a captive-bred male baboon presented with severe evidence of blood loss and melaena. an upper gastrointestinal radiological study with gastrografin showed a large trichobezoar. laparotomy confirmed its presence and revealed gastric ulceration with perforation and generalized peritonitis. the condition was successfully treated by surgery.19762366517
[chromosome band topography of papio hamadryas]. 1976827970
urinary steroid excretion and conjugation by the baboon (papio hamadryas)--a comprehensive study. 1976827659
field observation of a birth in hamadryas baboons.a birth in hamadryas baboons was observed during an 18-month field study in ethiopia. the behavior of the birth-giving female and the members of her harem unit are described.1976821828
antigenic characterization of c-type oncornavirus isolated from lymphomatous baboon (papio hamadryas).antigens of biln c-type oncornavirus isolated from lymphomatous baboon were studied in the double immunodiffusion. the major viral protein (p-30) of this virus possesses interspecies antigenic determinants (gs-3). this protein also revealed close antigenic relation to the p-30 of rd-114 and m-7 c-type oncornaviruses. specific serum against biln p-30 has been produced. the comparison of the three test-system (p-30s of m-7, rd-114, and biln, and specific sera against them) did not allow to disting ...197660981
anatomically orthogonal qrs electrocardiogram of the baboon (papio hamadryas) and the macaque (macaca mulatta). sex and species differences.peak amplitudes of the qrs complex were evaluated in 28 adult macaques (macaca mulatta) and 28 adult baboons (papio hamadryas), using two anatomically orthogonal lead systems. the anteroposterior (z) and the transversal (x) component of the cardiac electric field was smaller in females than in males. comparison of qrs amplitudes in baboons and macaques indicates that the loop of the spatial vectorcardiogram is situated further ventrally and to the right in the former. the relationship between ve ...1977140402
[demonstration by immunofluorescence of adenohyphysis corticotropin and melanotropin cells in erythrocebus patas, cercopithecus aethiops and papio hamadryas].using antibodies against synthetic corticotropic hormones (1-24 acth and 17-39 acth), and melanotropic hormones (alpha-msh and beta-msh), it is possible to identify corticotropic and melanotropic cells in the adenohypophysis of three species of monkeys : erythrocebus patas, cercopithecus aethiops and papio hamadryas. the corticotropic cells are numerous in the anterior lobe in both the adult and infant male and female monkeys of these three species. the intermediate lobe reacts with antibodies a ...1977196718
[effect of chlorimipramine on the so-called ponto-geniculo-occipitalactivity (pgo) in a primate, papio hamadryas (author's transl)].three hamadryas adult baboons (female) received 24 daily injections of chlorimipramine (1.7 mg/kg). the effects on sleep were nearly identical with the effects observed in man. pgo activity, recorded in the lateral geniculate nucleus, was much disturbed. the total number of pgo fell downward from the first recording. the number of pgo/min during paradoxial sleep was even more decreased. this fact suggests a selective influence of cl i on the mechanisms of pgo activity. is the particular effect o ...1977191866
nonhuman primates: laboratory animals of choice for neurophysiologic studies of sleep.a systematic study was made of several nonhuman primates to learn more about their relative usefulness for studies of sleep. species studied included the guinea baboon (papio papio), kenya or yellow baboon (p cynocephalus), olive baboon (p anubis), sacred baboon (p hamadryas), vervet monkey (cercopithecus aethiops), rhesus monkey (macaca mulatta), bonnet monkey (m radiata), crab-eating monkey (m fascicularis), patas monkey (erythrocebus patas), chimpanzee (pan troglodytes), mongoose lemur (lemur ...1977201798
[microscopic structure of the mesenteric lymph nodes of monkeys].the structure and cytoarchitectonics of mesenterial lymph nodes were studied in thin histological sections by different methods. under study were 5 rhesus monkeys and 3 hamadryas baboons. the square surface of different structural elements of the nodes (the cortical and medullary substances, follicles, the connective tissue framework, sinuses) occupied by them in sections was calculated and the amount of cellular elements was determined (%). comparison of the data obtained in rhesus monkeys and ...1977404995
[cytological structure of the thymus gland in mature monkeys].histological sections of the thymus were studied morphometrically in 5 rhesus monkeys and 3 hamadryas baboons. the ratio of square surfaces of the cortical and cerebral substance, the percentage of hassall's corpuscles and cellular elements (lymphocytes, stromal elements, blasts etc.) were established in the organ. individual and species peculiarities of the structure of thymus elements were found. less amount of parenchyma and growth of the stroma in baboons and a greater mitotic complex in rhe ...1977405958
[comparative characteristics of corticosteroid metabolism in lower simians and man].corticosteroid metabolism has been investigated in macaca mulatta, papio hamadryas, cercopithecus aethiops, erithrocebus patas and man. similar character of corticosteroid metabolism in monkeys and man was found. significant interspecific differences with respect to quatitative and qualitative parameters of the metabolism of steroid hormones were found. in this respect m. mulatta and p. hamadryas are most similar to man as compared with other monkeys. these two species may be used as an adequate ...1977409003
[duration and intensity of postvaccinal immunity to plague in experimental animals].experiments were conducted on guinea pigs and papio hamadryas; it was shown that a reduction of the intensity of postvaccinal immunity occurred at various periods after a single vaccination. in inhalation method of immunization in guinea pigs it decreased in 6 months 135 times, in monkeys in one year--133 times. however, at the mentioned periods vaccination provided protection of 50% of the animals from infection with past. pestis in a dose constitutin 20 to 25 aerosol ld50 for nonimmunized anim ...1977409008
the chromosomal location of rdna in selected lower primates.hybridization in stiu was used to identify the chromosomes that carry rdna in representative lower primates, including the baboons, papio cynocephalus and papio hamadryas; the colobus monkey, colobus polykomos; the tree shrew, tupaia glis; the lemur, lemur fulvis; the saki, pithecia pithecia; the marmoset, saguinus nigricollis, and the spider monkey, ateles geoffroyi. the marker chromosome, common to the cercopithecines studied to date, carries the rdna in the baboons. another marker chromosome ...1977414888
hematologic, biochemical, and physiologic indices of the sacred baboon (papio hamadryas).hematologic, biochemical, and physiologic indices for a recently imported group of sacred baboons, papio hamadryas, were studied over a 6-week period. hematologic values were in agreement with results recorded for other species of baboons. blood biochemical data were consistent with findings previously reported for other baboons and for man except that alkaline phosphatase levels were higher than previously for other baboons but similar to those reported for man; lactic dehydrogenase levels were ...1977857092
[chromosomes of 3 lymphoblastoid suspension cell lines obtained from baboons with malignant lymphoma].three suspension cell lines from bone marrow (bmph-1) and spleens (sph-2 and sph-3) of hamadryas baboons with haematosarcoma were presented by analogous lymphoid type cells of a high proliferative activity. the modal class of cells in all the three lines was presented by diploids and pseudodiploids, though there was a significant admixture of heterodiploid and subtriploid cells and cells having various types of marker chromosomes. the reconstructed chromosome 1 and satellite chromosomes dominate ...1977407685
[postcoital contraception in primates. i. action mechanism of a potential postovulatory fertility-inhibiting substance sts 456 in the baboon (papio hamadryas)].with the substance sts 456, an estrogenic active steroid, a high fertility inhibition could be obtained in the pavian, when administered p. o. over a 5 day period postcoital. the effectiveness and also the side effects were dose dependent. the antifertility mechanism is based on an luteolytic effect, demonstrated by analytical hormonal investigations. the inhibition of the synthesis of steroids in the ovary affected not only progesterone but also the estrogens.1978654663
inbreeding, lymphoma, genetics and morphology of the papio hamadryas colony of sukhumi. 1978156794
[nature of changes in the level of steroid hormones and their precursors in peripheral blood of papio monkeys under stress].the radioimmunological method was applied to determination of changes in the peripheral blood plasma level of 12 steroids in male papio hamadryas under immobilization and surgical stress. androgen content decreased, and the concentration of steroid hormone precursors and hydrocortisone blood plasma content rose in response to stress. these changes were in contraphase with the circadian steroid rhythms. the most objective and sensitive criteria of the stress situation evaluation were decrease of ...197896885
[characteristics of the ovarianc cycle in the baboon (papio hamadryas)].the dynamics of estradiol, estrone, 17 alpha-hydroxyprogesterone, progesterone and 20 alpha-dihydroprogesterone were investigated in the blood plasma of the pavian (papio, hamadryas) with regard to the menstrual cycle and in comparison with the human. furthermore results were presented about the basal temperature, the fern phenomenon and the development of the sex-skin in the pavian.1978349964
identification of the soluble hvp-associated antigen of the lymphoblastoid cell line established from lymphomatous baboon (papio hamadryas).a new technique (indirect double immunodiffusion) for detection of ebv-associated soluble antigen and corresponding antibodies has been developed. this technique includes three steps: 1) simple double immunodiffusion with extracts of raji cells (or other ebv-genome positive cells) and human sera containing antibodies against ebv-associated soluble antigen; 2) extensive washing and treatment with anti-human globulin; 3) extensive washing and treatment with tannic acid. using this test it was show ...1978219644
further characterization of a herpesvirus-positive orang-utan cell line and comparative aspects of in vitro transformation with lymphotropic old world primate herpesviruses.an orang-utan (pongo pygmaeus) suspension line, cp81, was shown to lack myeloid markers of lysozyme activity an d phagocytosis but to be positive for lymphocytic n-alkaline phosphatase activity, and to release a b-cell-tropic herpesvirus. this herpesvirus, termed herpesvirus pongo, had 30--40% dna homology with ebv and was present at 2-3 genome copies per cp-81 cell. gibbon lymphocytes transformed by h. pongo, epstein-barr virus (ebv), and h. papio (of baboon, papio hamadryas, origin) were found ...1978208990
[lung tissue alterations following experimental infection of mice with acholeplasmae isolated from simians with hematosarcoma].this paper is devoted to the study of pathogenic acholeplasmae potencies. two strains of acholeplasmae isolated from the blood and organs of papio hamadryas suffering from hemoblastosis and a standard ach. laidlawii a. strain were subjected to the comparative study with the use of a "pulmonary model" in experiments on mice. morphological investigations showed affections of the pulmonary tissue characterized by stage-by-stage inflammatory-destructive changes analogous to the lesions found in "myc ...1978665035
chemotherapy of helminthiasis among wild mammals. iv. efficacy of flubendazole 5% (r17889) against trichuris trichiura infection of baboons, papio hamadryas l.flubendazole 5%, a parafluor analog of benzimidazole derivative, mebendazole, was found efficient in eliminating trichuris trichiura infection of baboons when administered orally at a dose rate of 27 to 50 mg of the active ingredient per kg body weight twice daily for five days. the drug was found safe, without toxic effects and its palatability was excellent.1978754549
intracortical horizontal connections of neurons in cat and monkey motor cortex.the present paper deals with the study of the structure of horizontal neuron chains, one of the aspects of intracortical intraneuronal relationships. the motor cortex (field 4) of cats and lower monkeys (papio hamadryas and macacus rhesus s. m. mullata) was treated by the impregnating method of golgi--kopsh. the drawings of neurons from 90-micrometer sections were made by means of a camera lucida. three possible pathways of impulse transmission along neuron chains in a horizontal direction were ...1978216813
[cytoarchitectonics of ileocecal lymph nodes in newborn and sexually mature simians (pavian hamadrils)].cell composition of various components (cortical plateau, folliculi and cords) of ileocecal lymph nodes was studied in newborn, 1.5 and 2.5 months of age (2 animals) and in mature (3 animals) monkeys, papio hamadryas. in histological sections obtained at the level of hilus of the lymph node cellular elements were counted by means of morphometric grid of glagolev modifoed by s. b. stefanov. the data obtained were statistically treated. newborn and mature monkeys have their peculiar cytological pr ...197898135
[radioimmunologic method of determining 11 steroids in small samples of monkey blood plasma].a radioimmunological method is described for simultaneous estimation of hestagenes, estrogenes, androgenes and their precursors in small samples of blood plasma obtained from peripheric blood of hamadryads (papio hamadryas) and macaques (macaca rhesus). use of highly specific antisera and of chromatographic isolation of each steroid on columns with celite enabled to estimate the concentration of 11 steroids in 1.1 ml of blood plasma with high accuracy. standard curve and analysis of its linearit ...1979106544
antibody responses to herpesvirus papio antigens in baboons with lymphoma.an epstein-barr virus-related herpesvirus, termed herpesvirus papio (hvp), was isolated from baboons (papio hamadryas) at the institute of experimental pathology and therapy, sukhumi, ussr, where there is a continuing outbreak of lymphoma. in the present study sera from diseased baboons and from age- and sex-matched control animals were examined for antibodies to hvp antigens. results showed that animals with lymphoid disease had antibodies to hvp virus capsid, early, soluble, and nuclear antige ...1979216640
prevalence of antibodies to soluble antigen of epstein-barr virus-producing cells (p3hr-1) in the sera of hamadryas baboons of the high lymphoma incidence stock.soluble antigen of p3hr-1 cells (sa-p3hr-1) was identified in indirect double immunodiffusion enhanced with tannic acid using serum of a nasopharyngeal carcinoma patient containing high-titer antibodies to epstein-barr virus (ebv) antigens. sa-p3hr-1 was nonidentical to soluble antigen of raji cells. human and baboon sera containing antibodies to all the known antigen of ebv and hvp respectively were anti-sa-3hr-1-positive. human and baboon sera containing antibodies to all the known antigens of ...1979231520
[immunofluorescence demonstration of somatostatin-containing cells in the digestive tract of the monkeys irus, macaca papio hamadryas and cercopithecus aethiops].indirect immunofluorescence technique with antisomatostatin serum has allowed us to detect somatostatin containing cells in the gastro-intestinal tract of three species of monkeys : macacus irus, papio hamadryas and cercopithecus aethiops. these cells are localized only in the stomach, in the duodenum, and in the jejunum-ileum. no somatostatin cells were encountered in the esophagus and in the colon. the maximum of somatostatin positive cells is localized in the duodenum, as well in the lieberkü ...1979161187
[demonstration by immunofluorescence of somatostatin cells in the islets of langerhans in 3 species of monkeys].indirect immunofluorescence technique with anti-somatostatin serum has allowed us to detect somatostatin containing cells in the langerhans' islets of three species of monkeys (macacus irus, papio hamadryas, cercopithecus aethiops). these cells are in close relationship with another cells, but occupy a more central position in the islets. thus, the distribution of somatostatin-containing cells in the monkey's endocrine pancreas has not a similar pattern as in rodent's pancreas; they have a compa ...1979160269
immunofluorescent and immunoelectron microscopic demonstration of primate heart muscle antigens cross-reactive with streptococcus pyogenes.the presence of antigens in heart muscles cross-reactive with antibodies against streptococcus pyogenes were examined in heart samples of seven primate species (chimpanzee, rhesus macaque, stump-tailed macaque, hamadryas baboon, capuchin monkey, green monkey and patas monkey). cross-reactive antigens were localized by means of the indirect immunofluorescent technique in nearly all samples tested. the fluorescence pattern was the same as found in the heart muscle of other mammals. using the indir ...1979116866
[ileo-colonic lymph nodes in macaques and pavians of different ages].quantitative and qualitative alterations occurring in various structural components of the ileocolonic lymph nodes of papio hamadryas at the age of 3.5 months and 5 years and macaca rhesus at the age of 5 years were studied by means of mathematical methods. cellular composition was counted in every histological preparation per 1,000 cells in cortical plateau, in myelin cords, in follicles with light centers and in follicles without light centers. part (in %) of every cell variety was determined, ...1979116628
[experimental protective of fraction i of the plague microbe].the immunogenic properties of the freeze-dried preparation of fraction i tisolated from the culture of avirulent pasteurella pestis strain were studied in experiments on hamadryas baboons, guinea-pigs and white mice. the preparation was found to have a pronounced protective effect in hamadryas baboons and white mice, especially when the preparation was used in mixture with incomplete freund adjuvant. in hamadryas baboons resistance to infection was shown to correlate with hemagglutionation antib ...1979116458
[age and thymus morphology of pavian hamadrils].by different histological methods, 23 thymi have been studied in papio hamadryas of 5 age groups: fetuses, newborn, one-year-old, mature and old animals. by morphometric methods percentage of quantitative relations of the cortical and medullary substances, as well as their cell composition have been estimated. a rather great similarity in morphogenesis and age histology has been noted in human and monkey thymus. the character of histochemical reactions in thymus corpusculi supports the view on p ...1979111648
[frequency of radiation-induced exchanges in easily identifiable monkey chromosomes].frequency of asymmetric exchanges of readily identifiable chromosomes 1, 2, 3, 4, 8, 9 ad 20 was studied in primary kidney cell cultures of monkeys. macaca mulatta and papio hamadryas irradiated with 200 r of x-rays at g0. the chromosomes studied enter asymmetric exchange in accordance with their lengths of mitosis. the frequency of exchanges is independent of the quantity of late-replicating heterochromation in chromosomes. the radiosensitivity of chromosomes was identical in the two monkey spe ...1979552663
surface adhesive properties of baboon lymphocyte and derived lymphoblastoid cell lines.cell surface adhesiveness of lymphocytes isolated from the peripheral blood of papio hamadryas monkeys was compared to the adhesiveness of lymphoblastoid cell lines derived by transformation of these lymphocytes with herpesvirus papio. for the quantitative comparison of the cell surface adhesive properties, a recently developed latex particle adherence assay was utilized. it was found that cell surface adhesiveness of the suspension lines was substantially lower than that of their precursor lymp ...1979119650
effect of stress on the profile of plasma steroids in baboons (papio hamadryas).adult baboons (5 males and 5 females) were exposed to immobilization stress by being strapped to a table in a horizontal position for 2 h. in females the experiment was performed during both the follicular and luteal phase. peripheral blood was withdrawn at frequent intervals, the first sample just before immobilization, and the last one 3 days later. a number of steroids were measured in blood plasma samples by radioimmunoassay (17-hydroxypregnenolone, 17-hydroxyprogesterone, pregnenolone, test ...1979105533
peripheral plasma levels of 12 steroids during pregnancy in the baboon (papio hamadryas). 19807194812
[construction and cellular composition of the deep cervical lymph nodes of hamadryad baboons].the deep cervical lymph nodes in the papio hamadryas at the age of 1.5--2.5 years have a peculiar even distribution of the cortical and medullary substances, and in histological sections a comparatively small area is occupied by follicles (predominantly by those without light centers), myelin cords and some portal sinuses. every structure studied has its own set of cellular elements, but lymphocytes are the predominant cellular form in every structural component. plasmic cell content in the cort ...19807436763
steroid-induced ultrastructural changes in the proximal convoluted tubule cells of baboon kidneys with special reference to peroxisomes.an electron microscopic study was performed on kidneys of immature female baboons, papio hamadryas, that received a series of 10 consecutive weekly injections of the synthetic glucocorticoid, triamcinolone hexacetonide (4 mg/kg body wt). in the steroid-treated kidneys the most distinctive change found is a significant increase in the number and a marked change in the form of peroxisomes (microbodies) in proximal convoluted tubule cells. these cells also develop hypertrophic mitochondria and in s ...19807212287
fine structure of the parathyroid glands in baboons, papio hamadryas in response to experimental hypercorticoidism.female baboons maintained under laboratory conditions were subjected to a series of 10 weekly injections (4 mg/kg body weight) of the synthetic glucocorticoid, triamcinolone hexacetonide. in response to the treatment, serum immunoreactive parathyroid hormone (pth) levels were raised, though blood calcium levels remained within normal physiological limits. light and electron-microscopic studies were made on the parathyroid glands at the end of the experimental period. the baboon parathyroid gland ...19806770575
lymphocyte sensitization detected in lymphomatous hamadryas baboons by the macrophage electrophoretic mobility assay.peripheral blood lymphocytes from lymphomatous or control papio hamadryas monkeys were incubated in the presence of kcl-extracted proteins prepared from allogeneic lymphomatous or normal lymph nodes and from a spontaneous baboon hepatoma. only the lymphomatous baboon lymphocyte-lymphoma antigen interaction product(s) significantly reduced the anodic electrophoretic mobility of guinea pig macrophages.19806244991
antistreptococcal antibodies, rheumatoid factors and haptoglobin in apes and monkeys.sera of 157 baboons (papio hamadryas and p. anubis) 21 chimpanzees (pan troglodytes) five orang utans (pongo pygmaeus) three mountain gorillas (gorilla gorilla beringei) and three gibbons (hylobates lar lar) were examined for the content of antistreptolysin o, antidesoxyribonuclease b, for the presence of rheumatoid factors as well as for the level and type of haptoglobin. the mean antistreptolysin o titer (ast) in baboons was 106 asu +/- 18 in dextransulfate absorbed sera ("real" ast) and 182 a ...19806775442
isolation of lymphotropic baboon herpesvirus (hvp) from oral swabs of hamadryas baboons of the sukhumi monkey colony.ways of lymphotropic baboon herpesvirus (hvp) secretion and its excretion into the environment were investigated. oral swabs and feces from the sukhumi main stock hamadryas baboons characterized by a high risk for malignant lymphoma and the baboon stock living in isolation in the forest were used as materials for the investigations. macaque groups of the sukhumi stock were used as controls. it could be shown that the hvp was resistent in the oral cavity of the main stock baboons and was isolated ...19807409079
a reassessment of the karyotype of papio ursinus. homoeology between human chromosome 15 and 22 and a characteristic submetacentric baboon chromosome.the giemsa-banded karyotype of the chacma baboon, papio ursinus, was shown to be identical to that of papio hamadryas. comparison of g-banded p. ursinus (pur) chromosomes with those of man (hsa) showed close morphological homoeology between pur and hsa chromosomes 5, 8, 12, 19, and x, and partial homology for seven and 22 and was the only papio chromosome containing a nucleolar organizer region (nor). this baboon chromosome, therefore, shows genetic homoeology with human acrocentrics for a least ...19807449436
[structural organization of caudate-frontal relationships in lower monkeys].cellular structure of the caudate nuclei has been studied in intact monkeys (macaca rhesus and papio hamadryas) after bilateral extirpation of the frontal area fields. methods of retrograde cellular degeneration and quantitative analysis with application of the computer "klassimat" have been used. only in one macaca operated on, the frontal premotor and motor fields have been removed, in other monkeys the frontal fields have been predominantly removed. only in one macaca operated on, a statistic ...19817034692
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