Publications

codon-optimized filovirus dna vaccines delivered by intramuscular electroporation protect cynomolgus macaques from lethal ebola and marburg virus challenges.	cynomolgus macaques were vaccinated by intramuscular electroporation with dna plasmids expressing codon-optimized glycoprotein (gp) genes of ebola virus (ebov) or marburg virus (marv) or a combination of codon-optimized gp dna vaccines for ebov, marv, sudan virus and ravn virus. when measured by elisa, the individual vaccines elicited slightly higher igg responses to ebov or marv than did the combination vaccines. no significant differences in immune responses of macaques given the individual or ...	0	25996997
chikungunya virus in macaques, malaysia.		0	26291585
'vincent's disease' in a macaca irus monkey.		1933	29009456
comparative studies on the viruses of vesicular stomatitis and equine encephalomyelitis (1).	we have studied certain properties, additional to those previously described (3), of the virus of vesicular stomatitis of horses, and of the characteristic biological reactions of the virus of equine encephalomyelitis. it has been found that the virus of stomatitis, ordinarily dermotropic, can acquire neurotropism and the neurotropic encephalomyelitis virus can, in turn, be rendered dermotropic in its action. the neurotropism in both instances is associated with definite, although not pronounced ...	1934	19870237
experimental air-borne infection with poliomyelitis virus.	infection has been obtained in both rhesus and cynomolgus monkeys by inhalation of poliomyelitis virus in the form of droplet nuclei. the olfactory route was excluded in part of the animals successfully infected. the gastrointestinal route is believed to have been excluded in the rhesus monkeys. it seems most probable that the portals of entry were the lower respiratory mucosa in the case of the rhesus monkeys and the oropharyngeal mucosa in the case of the cynomolgus monkeys. fever and occasion ...	1941	17821267
pathway of invasion in a cynomolgus monkey after oral application of poliomyelitis virus.		1942	17743466
the detection of poliomyelitis virus in flies collected during epidemics of poliomyelitis : i. methods, results, and types of flies involved.	1. a series of 19 different samples of flies collected within epidemic areas during and after the onset of nearby human cases of poliomyelitis have been tested for the virus of poliomyelitis. four of these samples proved positive. 2. methods used in collecting the flies, preparing the inocula, and examining the inoculated monkeys (and other animals) are described. 3. all of the positive tests were obtained by the intranasal and intra-abdominal inoculation of java (cynomolgus) monkeys. green afri ...	1943	19871302
susceptibility of cebus capucina (the south american ringtail monkey) and cercopithecus cephus (the african mustache monkey) to poliomyelitis virus.	1. the south american ringtail monkey, cebus capucina, has been infected with the virus of poliomyelitis as found in ultracentrifuged concentrates from poliomyelitic human stools. 2. this species was also found susceptible to poliomyelitis virus found in rhesus and cynomolgus monkey cords, representing early generations of virus derived from two different human sources and from flies trapped in an epidemic area. 3. the hartford strain of poliomyelitis has been successfully established in differe ...	1943	19871327
poliomyelitis in the cynomolgus monkey : i. comparison of the upper portion of the alimentary tract with its lower, gastrointestinal portion as a portal of entry, with special reference to the peripheral ganglia.	1. cynomolgus monkeys were subjected to a series of non-traumatic exposures of the mucous membranes of the alimentary tract, designed to test the relative permeability to poliomyelitis virus of its upper and lower portions. 2. in the first stage, dried poliomyelitis virus of tested potency was administered in fat-covered capsules to 26 monkeys in such a way as to avoid contamination of the oropharynx but to permit thorough exposure of the gastro-intestinal mucosae. no clinical evidence of poliom ...	1943	19871345
poliomyelitis in the cynomolgus monkey : ii. resistance to spread of infection in the central nervous system following exposures of the mucous membranes to virus, with comments on non-paralytic poliomyelitis.	1. repeated non-traumatic exposures to poliomyelitis virus of the mucous membranes of the upper respiratory tract and of various portions of the alimentary tract in 5 cynomolgus monkeys, extending over a period of 9 to 14 months, were followed by a definite, though limited resistance to intracerebral inoculation to the homologous strain of virus in 4 of them. only one monkey developed paralysis (20 per cent incidence) and the other 4 remained free of signs and symptoms of the disease. 92 per cen ...	1943	19871346
poliomyelitis in the cynomolgus monkey : iii. infection by inhalation of droplet nuclei and the nasopharyngeal portal of entry, with a note on this mode of infection in rhesus.	1. poliomyelitis virus suspensions were atomized so as to produce dry droplet nuclei which, suspended in air, were introduced into a special infecting chamber and inhaled by test animals, both rhesus and cynomolgus monkeys. 2. without olfactory blockade, 5 of 7 rhesus and 6 of 7 cynomolgus monkeys developed poliomyelitis of the cns with entry through the olfactory nerves. 3. with olfactory blockade, 2 of 35 rhesus and 4 of 10 cynomolgus monkeys developed this form of the disease by routes proved ...	1944	19871397
purified human poliomyelitis virus; infectivity for cynomolgus monkeys.		1948	18869319
poliomyelitis in the cynomolgus monkey; further observations on exposures confined to the stomach and intestines, with notes on the fecal excretion of virus.	36 exposures of the stomach and intestines of 18 cynomolgus monkeys to large doses of poliomyelitis virus by a method designed to avoid simultaneous exposure of the oropharynx and upper esophagus induced poliomyelitis in only one instance. these observations are to be compared with a previous study in which exposures of the entire alimentary tract including oropharynx and upper esophagus by simple feeding of comparable amounts of the same strain resulted in poliomyelitis in half of the test anim ...	1948	18871878
poliomyelitis in philippine cynomolgus monkeys after simple feeding.		1948	18872699
poliomyelitis in the cynomolgus monkey following oral inoculation.		1948	18872700
announcement of a twin birth in java macaques; macaca irus mordax thomas u. wroughton cynomolgus l.		1948	18881044
studies on the entry and egress of poliomyelitic infection : i. neutrotropic infection of the peripheral ganglia in apparently healthy monkeys following casual exposure.	in rhesus and cynomolgus monkeys without signs or symptoms of poliomyelitis, a comparison of the incidence, numbers, size, and character of lesions in certain peripheral ganglia (gasserian, nodose, superior cervical sympathetic, and celiac) was made between 9 "new" animals sacrificed 1 to 3 days after arrival in a laboratory devoted exclusively to poliomyelitis research, and 17 "old" animals housed there without special isolation precautions for periods ranging from 17 days to 10(1/2) months. th ...	1950	19871717
[further observations and investigations on reproduction in the java macaque (macaca irus mordax th. et wr., cynomolgus l.)].		1950	14777537
studies on entry and egress of poliomyelitic infection. iv. atraumatic oral entry distribution of lesions and virus during the incubation period with notes on asymptomatic poliomyelitis.	within 48 hours after simple oropharyngeal exposures of cynomolgus monkeys to poliomyelitis virus, histological signs of infection were found in ganglia supplying the exposed mucous membranes. at 3 days, virus was found in the gasserian, petrosal-nodose, and superior cervical sympathetic ganglia. lesions were most extensive and severe in the gasserian. virus continued to be detected daily from the 3rd to the 8th day, inclusive, in the gasserian but not on the 9th; from the 3rd to the 6th day, in ...	1951	14897993
experimental studies on passive immunization against poliomyelitis. ii. the prophylactic effect of human gamma globulin on paralytic poliomyelitis in cynomolgus monkeys after virus feeding.		1952	14933392
inoculation of cynomolgus monkeys with coxsackie virus alone, combined, or with poliomyelitis virus.		1952	14938549
homotypic complement-fixing antibody in monkeys infected with type 2 poliomyelitis virus by the oral route.	cf tests with type 2 poliomyelitis antigen (mef1) were performed on the pre- and postinfection sera of 20 cynomolgus monkeys which developed paralytic, non-paralytic, or inapparent infection following oral administration of a type 2 strain of virus (y-sk). all the monkeys developed neutralizing antibody, and 17 developed cf antibody in an original serum dilution titer of 1:4 or greater. the 3 monkeys which did not develop this level of cf antibody were in a group of 7 which died within 8 days af ...	1952	14946328
human gamma globulin in the protection of tonsillectomized cynomolgus monkeys with experimental poliomyelitis.		1952	14884738
studies on entry and egress of poliomyelitic infection. v. entry after simple feeding: with notes on viremia.	poliomyelitis virus, when ingested by cynomolgus monkeys in their regular food, infected peripheral ganglia (nodose) as early as the 3rd day, as shown by recovery of the virus. conditions on the 2nd and 4th days were not investigated, but on the 5th and 6th days, virus was recovered from the gasserian and nodose ganglia, and from the superior cervical sympathetic and celiac ganglia. the findings indicate that the method of oropharyngeal swabbing used in a study already reported and the method of ...	1953	13022863
prevention of paralytic poliomyelitis in tonsillectomized cynomolgus monkeys by human gamma globulin.		1953	13023105
on the incidence and locations of nerve cells in the spinal white matter of two species of primates, man and the cynomolgus monkey.		1953	13084786
presumed exo-erythrocytic schizonts of plasmodium knowlesi in the liver of a malayan monkey (macaca irus).		1953	13102580
antiviral action of a mold filtrate on experimental poliomyelitis in cynomolgus monkeys.		1954	13134303
studies on variants of poliomyelitis virus. i. experimental segregation and properties of avirulent variants of three immunologic types.	attempts were made to "convert" highly virulent strains of the 3 immunologic types of poliomyelitis virus (mahoney, y-sk, and leon) into avirulent variants. tests involving intracerebral, intramuscular, or oral administration of virus to cynomolgus monkeys indicated that mere propagation in cultures of kidney tissue of cynomolgus monkeys had no effect on virulence when single or small numbers of virus particles were used as seed, and harvests were delayed for 24 hours or more after the appearanc ...	1954	13163327
demyelinating encephalomyelitis in a cynomolgus monkey following vaccination against smallpox and simultaneous inoculation of a neutropic virus recovered from a case of postvaccinal encephalitis.		1954	13171854
transmission of the avian infectious bronchitis virus to the cynomolgus monkey.		1954	13200090
the distribution of poliomyelitis virus in cynomolgus monkeys following oral administration, tonsillectomy, and intramuscular injection of diphtheria toxoid.		1955	13259508
studies on entry and egress of poliomyelitic infection. viii. the relation of viremia to invasion of the central nervous system.	1. the effects of viremia on the cns of cynomolgus monkeys were studied by comprehensive histological examination following inoculations of approximately equal amounts of the same strain of poliomyelitis virus into the femoral vein, carotid artery, and vertebral artery, respectively, of four animals in each case. 2. the intravenous injections failed to produce lesions in the cns, indicating that an effective mechanism exists for the removal of virus from the blood stream. while not absolute, the ...	1955	14354108
local increase of poliomyelitis virus in healing wound tissue of cynomolgus monkeys.		1955	14384886
further observations on the widespread distribution of poliomyelitis virus in body tissues following intramuscular inoculation of cynomolgus monkeys.		1956	13299704
on the adult morphology of wuchereria sp. (malayi?) from a monkey (macaca irus) and from cats in malaya, and on wuchereria pahangi n.sp. from a dog and a cat.		1956	13319678
diseases seen at necropsy of 708 macaca mulatta (rhesus monkey) and macaca philippinensis (cynomolgus monkey).		1957	13424939
studies on the dentition of the cynomolgus monkey.		1957	13428901
primary sites of virus multiplication following intramuscular inoculation of poliomyelitis virus in cynomolgus monkeys.		1957	13443206
[cytopathogenic agents isolated from monkeys (macaca rhesus and macaca cynomolgus). i. their behavior in cultures of monkey kidney cells and kb cells].		1957	13489094
poliomyelitis as a complex infection.	young cynomolgus monkeys inoculated intracerebrally with an attenuated type 1 polio virus and, after 5 days, with a monkey adapted coxsackie a-14 virus frequently became paralyzed. neither virus alone was capable of inducing paralysis. similar results were observed when the ab iv strain of coxsackie a-7 was substituted for the a-14 virus. in this case the 2nd inoculation was made intramuscularly. paralytic poliomyelitis may at times represent the summation of two infections, the total of motor n ...	1958	13587845
the virulence and immunogenicity of 23 c-adapted polioviruses. i. in cynomolgus monkeys following inoculation by alimentary and intramuscular routes.		1959	13843984
dirofilaria magnilarvatum price, 1959 (nematoda: filarioidea) from macaca irus cuvier. iii. the behavior of the microfilariae in the mammalian host.		1959	14400251
dirofilaria magnilarvatum price, 1959 (nematoda: filarioidea) from macaca irus cuvier. iv. notes on larval development in mansonioides mosquitoes.		1959	13844259
dirofilaria magnilarvatum price, 1959 (nematoda: filarioidea) from macaca irus cuvier. ii. microscopical studies on the microfilariae.		1959	13837108
dirofilaria magnilarvatum n. sp. (nematoda: filarioidea) from macaca irus cuvier. i. description of the adult filarial worms.		1959	14434843
the pathogenesis of poliomyelitis. sites of multiplication of poliovirus in cynomolgus monkeys after alimentary infection.		1960	13843985
the effect of cortisone on the course of tick-borne encephalitis infection in cynomolgus monkeys.		1960	13848999
[an experiment on the study of the properties of sch cell strain (cynomolgus monkey heart cells) by the method of inoculation into immunized monkeys and re-explantation].		1960	13793648
pathogenesis of variola in macaca irus monkeys.		1960	14398863
[the results of morphological study of the stability of cultures of cynomolgus monkey heart cells (sch) in vivo].		1960	14442060
on a new filarioid worm, edesonfilaria malayensis gen. et sp. nov. from the long-tailed macaque (macaca irus).		1960	13787292
haptoglobulin types in macaca irus.		1960	13798151
haptoglobin types in macaca irus.		1960	13688544
the vacuolating virus of monkeys. i. isolation, growth characteristics, and inclusion body formation.	a vacuolating virus isolated from uninoculated patas monkey kidney cultures was found to be serologically identical with sv(40), a virus previously found in association with rhesus and cynomolgus monkeys. detection of the patas virus was facilitated when patas cells were exposed to x-ray treatment. rhesus monkey and human cells were relatively insusceptible to the virus, although it persisted in these cells for a long period of time. distinct intranuclear inclusions were detected in infected pat ...	1961	14449527
diagnosis of human allergy utilizing passive skin-sensitization in the monkey macaca irus.		1961	14463064
[antibodies against measles virus in the monkey macaca irus imported to japan].		1961	14495811
air-borne infectivity of the variola-vaccinia group of poxviruses for the cynomolgus monkey, macaca irus.		1961	13903693
the effect of guanidine: (1). on experimental poliomyelitis induced by oral administration of virus to cynomolgus monkeys; (2). on naturally occurring enteroviruses of cynomolgus monkeys.		1961	13865226
experimental infections with coxackie viruses. ii. myocarditis in cynomolgus monkeys infected with b 4 virus.		1961	13763654
hemoglobin types of macaca irus and macaca mulatta monkeys.	hemoglobin of 30 macaca mulatta monkeys and of 15 macaca irus monkeys consisted of one electrophoretic component similar to human hemoglobin a. twenty-one m. irus monkeys had two types of hemoglobin. in 20 animals the hemoglobin resembled human hemoglobin aj, and in one animal it resembled human hemoglobin ai.	1961	13778808
experimental infections with coxsackie viruses. i. studies on virulence and pathogenesis in cynomolgus monkeys.		1961	13784380
transferrin variations in sera of macaca irus.		1961	13688545
infection of rhesus and cynomolgus monkeys with egg-grown viruses of trachoma and inclusion conjunctivitis.		1962	13884031
immunization against brucella infection. 8. the response of cynomolgus philippinensis, guinea-pigs and pregnant goats to injection by the rev i strain of brucella melitensis.	experiments have been carried out on monkeys, goats and guinea-pigs to define as closely as possible the degree of attenuation of the rev i strain of b. melitensis. earlier studies had conclusively demonstrated the effectiveness of the strain as an immunizing agent of the three animal species and had suggested that the degree of attenuation was such as to warrant limited study in humans. results of such a limited study suggested more intensive measurement of the virulence of the strain in other ...	1962	13889789
establishment of a cell strain, jtc-12, from cynomolgus monkey kidney tissue.		1962	13984589
allergy skin tests upon castorbean-sensitive humans and passively sensitized cynomolgus monkeys.		1962	14463065
quantitation of the infectivity for cynomolgus monkeys of egg-grown inclusion conjunctivitis virus. a comparison of the clinical course of the experimental disease, the appearance of inclusion bodies and the regular recovery of the viral agent.		1962	14475837
studies on the transferrins of adult serum, cord serum, and cerebrospinal fluid. the effect of neuraminidase.	nine of the twelve known variants of human transferrin have been resolved by the action of neuraminidase into stepwise patterns of four additional slower moving components whose relative intensities depended upon the concentration of enzyme. these components appeared to represent the stepwise removal of the four sialic acid residues from the transferrin molecule, and at large enzyme concentrations, almost all of the transferrin was reduced to the position of the slowest moving component. in cont ...	1962	14483938
morphologic and immunohistochemical studies of the pathogenesis of infection and antibody formation subsequent to vaccination of macaca irus with an attenuated strain of pasteurella tularensis: i. intracutaneous vaccination.		1962	19971016
morphologic and immunohistochemical studies of the pathogenesis of infection and antibody formation subsequent to vaccination of macaca irus with an attenuated strain of pasteurella tularensis: ii. aerogenic vaccination.		1962	19971017
[studies on the lymphatic system of the inguinal region and reproductive organs in male crab-eating macaques].		1962	13923419
the spinal arachnoid villi of the monkeys cercopithecus aethiops sabaeus and macaca irus.		1963	13999821
[experimental studies in the cynomolgus monkey, of the penetration, in the body, of poliomyelitis virus sprayed by nasal route].		1963	14026274
an experimental study of the accessory optic system in the cynomolgus monkey.		1963	14051848
trachoma viruses isolated in the united states. vi. cross-immunization studies in cynomolgus monkeys with strains of trachoma and inclusion conjunctivitis viruses.		1963	14064885
[postirradiation recovery of cynomolgus monkey heart cells subjected to gamma-irradiation].		1963	14068180
[antigenic properties of cultivated cynomolgus monkey heart cell cultures and amniotic fluid of cattle].		1963	14071292
observations on the diurnal temperature variation of cynomolgus monkeys (macaca irus) and on the effect of changes in the routine lighting upon this variation.		1963	14071902
statistical survey of internal parasites in cynomolgus monkeys (macaca irus).		1963	14071905
significance of the natural infection of oesophagostomum sp. in cynomolgus monkeys (macaca irus) used as experimental animals.		1963	14071906
a new sub-species of plasmodium knowlesi in the long-tailed macaque.		1963	13960457
hepatocystis from macaca irus in java.		1963	14084192
[the temporal muscle in macaca irus. supplement: a view on the origin of the torus supraorbitalis].		1963	14095674
a contribution to the knowledge of some craniologic, craniometric, and growth changes in skulls of macaca mulatta and macaca irus (cynomolgus).		1963	14133062
[penetration of the poliomyelitis virus and its movement within the body of the infected animal. experimental trials on the cynomolgus monkey].		1964	14129160
n-terminal residues of adult hemoglobins from macaca mulatta and macaca irus monkeys.		1964	14162517
immunization against brucella infection. 10. the relative immunogenicity of brucella abortus strain 19-ba and brucella melitensis strain rev i in cynomolgus philippinensis.	continuing previous studies, the authors investigated the immunogenicity of low doses of brucella melitensis strain rev i in cynomolgus monkeys challenged by the respiratory route and compared the efficacy of rev i vaccine with that of vaccine from br. abortus strain 19-ba.challenge with the virulent br. melitensis strain 6015 indicated that 19-ba vaccine was considerably more effective when administered intracutaneously than subcutaneously, whereas with rev i vaccine the difference was slight, ...	1964	14196815
comparative studies of the effect of pilocarpine on the pupil and on the refraction in two species of monkey (cercopithecus ethiops and macaca irus).		1964	14203330
chromosome studies during long-term cultivation of epithelioid cercopithecus and cynomolgus monkey kidney cell lines.		1964	14220247
a newly discovered myxovirus (s.v.41) isolated from cell cultures of cynomolgus monkey kidney.		1964	14225927
shigellosis in cynomolgus monkeys (macaca irus). i. epidemiological surveys on shigella infection rate.		1964	14235610
variable susceptibility of cynomolgus monkey kidney cells to the specific cytopathic effect of simian virus 40.		1964	14279862
shigellosis in cynomolgus monkeys (macaca irus). ii. experimental infection with shigella flexneri 2a with special references to clinical and bacteriological findings.		1964	14279864
shigellosis in cynomolgus monekys (macaca irus). 3. histopathological studies on natural and experimental shigellosis.		1964	14279865
detection of measles viral antigen in the lymph nodes of cynomolgus monkeys infected with measles.		1964	14280998
rhesus and crab-eating macaques: intergradation in thailand.	conspecificity of the rhesus macaque, macaca mulatta mulatta (zimmermann, 1780), and the crab-eating macaque macaca mulatta fascicularis (raffles [1821]), is established by a geographically intermediate series of three specimens transitional in tail length and coat color.	1964	17821058
[study on virus-chromosome relationships. ii. detailed karyotypes of macaca irus, erythrocebus patas and cercopithecus aethiops sabaeus].		1964	14145256
effect on refraction of intramuscular pilocarpine in two species of monkey (cercopithecus aethiops and macaca irus).		1965	14283015
the aqueous humor drainage mechanism in the cynomolgus monkey (macaca irus) with evidence for unconventional routes.		1965	4157891