Publications

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a clarification of the relationship of candida guilliermondii to other yeasts by a study of their mating types. 195413211564
[biosynthesis of riboflavin in candida guilliermondii (a. cast) langeron and guerra and some related species; influence of trace elements, especially iron and zinc]. 195713522136
[stimulation of riboflavin synthesis in yeasts candida guilliermondii in the presence of iron in culture medium]. 195813632416
[r-s variation in candida guilliermondii (cast) langerón & guerra]. 195813656499
[effect of iron on the synthesis of riboflavin in respiratory systems of yeasts candida guilliermondii]. 195914445623
successive microbial populations in calimyrna figs.smyrna-type (calimyrna) figs have essentially sterile internal tissue until visited by the pollinating fig wasp, blastophaga psenes, which introduces a specific microflora consisting of candida guilliermondii var. carpophila and serratia plymuthica. this flora persists and develops in numbers throughout the ripening period until maturity of the fruit. these organisms do not cause spoilage. the presence of c. guilliermondii var. carpophila appears to increase the attractiveness of the fruit to dr ...196216349620
studies on the pathogenesis of experimental candida parapsilosis and candida guilliermondii infections in mice. 196514331713
validation of the species pichia guilliermondii. 19665926749
[on the role of xanthine in riboflavine biosynthesis by the yeast candida guilliermondii]. 19665995919
[the effect of the carbon source on the rate of growth, protein content and enzymatic pattern of candida guilliermondii]. 19685706730
[the rate of flavinogenesis in candida guilliermondii at the logarithmic phase of growth and its changes under different growth conditions]. 19685733235
[influence of nitrogen nutrition sources on flavin accumulation in yeast cultures candida guilliermondii]. 19685733680
[rate of flavinogenesis in candida guilliermondii growing on media with a deficit of various nutrient substances]. 19685734405
[production of deficient mutants of candida guilliermondii with methanesulfonic acid ethyl ester]. 19684387708
[dynamics of flavin accumulation in cultures of candida guilliermondii growing on media with different iron content]. 19695345735
on the relations between enzyme activities, protein synthesis, and maximal growth rate in candida guilliermondii. 19695312035
some properties of metabolities produced by the hydrocarbonoxidizing yeast candida guilliermondii. 19695312050
[peculiarities of candida guilliermondii metabolism with different flavinogenesis]. 19695346127
purine metabolism and riboflavin overproduction in candida guilliermondii. 19695312017
[purine metabolism and riboflavin formation in microorganisms. ii. purine metabolism and riboflavin synthesis of a purine deficiency mutant of candida guilliermondii (cast.) lang. et g]. 19695369708
microbial production of xylitol from glucose.a microbiological method is described for the production of xylitol, which is used as a sugar substitute for diabetics. a sequential fermentation process yielded 9.0 g of xylitol from 77.5 g of glucose via d-arabitol and d-xylulose. candida guilliermondii var. soya (atcc 20216) consumed 5.1 g of d-xylulose and produced 2.8 g of xylitol per 100 ml. pentitol production from d-xylulose by yeasts was divided into three types: i, yeast-produced xylitol; ii, yeast-produced d-arabitol; and iii, yeast-p ...19695370655
[acid-soluble nucleotides and their derivatives in the cells of candida guilliermondii during various intensities of flavin biosynthesis]. 19695801315
[candida guilliermondii as an accompanying germ of madurella mycetomi. settling of yeast colonies in the depressions of the uneven black mycetoma plaques]. 19705464088
[a cytosine deficient mutant of the yeast candida guilliermondii capable of synthesizing large quantities of riboflavin]. 19705517371
[purine metabolism and riboflavin production in microorganisms. vi. the effect of l-valine on the flavinogenesis of candida guilliermondii (cast.) lang. et g]. 19705453893
[purine metabolism and riboflavin production in microorganisms. vii. regulation of purine nucleotide synthesis through adenine in candida guilliermondii (cast.) lang. et g]. 19705453894
[nucleotides and their derivatives in the culture fluid of yeasts of candida guilliermondii with different flavinogenous activity of cells]. 19705503963
[flavinogenesis in guanine-dependent mutants of candida guilliermondii]. 19715573210
[candida guilliermondii mutants with blocked catabolism of purines and flavinogenic activity of these mutants]. 19715130739
[purine metabolism and riboflavin synthesis in microorganisms. v. biotin dependence of urea splitting by candida guilliermondii (cast.) lang. et g]. 19715148327
the genus candida berkhout. xi. electron microscopy and roentgen-phase analysis of cell walls of three strains of candida guilliermondii (cast.) langeron et guerra. 19715125361
candida guilliermondii septicemia. 19715126667
[purine metabolism and riboflavin biosynthesis in microorganisms. iv. storing of riboflavin in the cells of candida guilliermondii (cast.) lang. et g]. 19715563613
[mutants of candida guilliermondii with damage to various groups in the biosynthesis of inosinic and adenylic acids]. 19715580122
the genus candida berkhout. xii. chemical composition of polysaccharides isolated from cell walls of three strains of candida guilliermondii (cast.) langeron et guerra and their immunochemical properties. 19715004100
[effect of temperature on growth, cell composition, and metabolic activity of candida guilliermondii]. 19724678971
[change in the intensity of nad-h 2 fluorescence in candida guilliermondii yeasts during transition from anaerobic to aerobic states]. 19724347836
[antagonism between purines and pyrimidines in the nutrition of mutants of candida guilliermondii yeasts]. 19724657958
[role of purine biosynthesis de novo in the flavinogenesis of candida guilliermondii]. 19725061665
[localization of hydrocarbons in cells of candida guilliermondii np-4 yeasts, cultivated on media with paraffins]. 19725086810
[preparation and properties of riboflavin-dependent mutants of pichia guilliermondii wickerham yeasts]. 19724657965
[purine transport in pichia guilliermondii yeasts]. 19724662625
[the significance of the ph of the medium for growth of the yeast candida guilliermondii when cultured on media with organic acids]. 19734772145
[optimization of growth conditions for candida guilliermondii, strain h17]. 19734781168
[purification and some properties of the alkaline phosphatase i of pichia guilliermondii yeasts]. 19734790755
[role of flavins in regulating riboflavin synthetase synthesis in pichia guilliermondii and candida utilis]. 19734798715
thrush of urinary bladder due to candida guilliermondii. 19734513638
[formation of dicarbonic acids by candida guilliermondii, strain h 17, from n-alkanes]. 19734707933
letter: osteomyelitis of cervical spine: candida guilliermondii. 19734751750
[urea assimilation in the yeast candida guilliermondii using atp: urea amidolyase]. 19734762319
[the effect of aeration intensity on atp content in candida guilliermondii h-249 yeast cells assimilating organic acids]. 19734771028
[isocitrate lyase from candida guilliermondii, strain h 17. i. purification and characterisation]. 19734774657
[purine metabolism and riboflavine formation in microorganisms. xi. studies on the nature of purine precursor for riboflavine in candida guilliermondii]. 19734774672
[study of flavin genesis by pichia guilliermondii yeast mutants with damaged heme synthesis]. 19734791160
the influence of iron concentration and temperature on growth and riboflavin overproduction of candida guilliermondii. 19734802624
the role of nitrogen and phosphorus in protein synthesis by candida guilliermondii cultivated on n-alkanes. 19734802634
[the effect of substrate concentration of n-alkanes on lipid biosynthesis by candida guilliermondii yeasts]. 19744830966
[isocitrate lyase of candida guilliermondii, strain h17. ii. regulation by selected intermediates of the tricarboxylic acid cycle and hexose catabolism]. 19744365777
[study of the polyphosphate-phosphohydrolase activity in the cells of the yeast candida guilliermondii which assimilates petroleum hydrocarbons under various cultivation conditions]. 19744375809
mutants of asporogenic yeasts susceptible to staining on a medium with eosin and methylene blue. ii. mutants of candida guilliermondii. 19744133399
[the effect of guanine on the growth, variability and de novo biosynthesis of purines by pichia guilliermondii mutants with guanine deaminase block]. 19744449488
[the influence of aeration and iron concentration on porphyrin synthesis by candida guilliermondii]. 19744449491
[consumption of different molecular weight n-paraffins by candida guilliermondii yeasts]. 19744463351
[obtaining hybrids of haploid strains of pichia guilliermondii wickerham that assimilate petroleum hydrocarbons]. 19744465659
[correlation between growth and uptake of excreted riboflavin in candida guilliermondii]. 19744467480
[isocitrate lyase of candida guilliermondii, strain h17. ii. regulation by selected intermediates of the tricarboxylic acid cycle and hexose degradation]. 19744464656
[isocitrate lyase of candida guilliermondii, strain h17. iii. regulation by intermediates of alkane degradation and a general regulation model]. 19744464657
[isocitrate lyase of candida guilliermondii, strain h17. 3. regulation by intermediates of alkane catabolism and general model of regulation]. 19744836322
[catabolism of tryptophan by candida guilliermondii, strain h17]. 19744408763
[nature of riboflavin precursors in pichia guilliermondi yeasts].thirty-nine riboflavin-deficient mutants have been isolated from three yeast strains of pichia guilliermondii (atss 9058, vkm y-1256, vkm y-1257) and f5-121 mutant which is capable of production of large amounts of riboflavin in the presence of iron in the medium. all mutants were divided into five groups according to the nature of precursors accumulated in the medium and growth reaction in media with 6,7-dimethyl-8-ribityllumasine and diacetyl. the mutants of the first group did not accumulate ...19751160636
[variability in the flavinogenic activity of pichia guilliermondi yeasts].the natural and induced variability of the flavinogenic activity was studied in the strain of pichia guilliermondii atcc 9058. the flavinogenic activity of the collection strain showed normal distribution; the amount of riboflavin(rf) accumulated in the medium differed several times in the extreme variants. in the clones with the maximum and minimum accumulation of rf, the distribution of the variants was asymmetric, due to the appearance of the cells with an average flavinogenic activity. the c ...19751160648
biosynthesis of flavins and its regulation in the yeast pichia guilliermondii.the nature of riboflavin precursors was studied in the yeast pichia guilliermondii. by means of mutants with blocked gmp-synthetase the purine precursors of riboflavin were shown to belong to guanylic compounds. accumulation of 2,4,5-triamino-6-oxypyrimidine, 2,5-diamino-6-oxy-4-ribitylaminopyrimidine, 2,6-dioxy-5-amino-4-ribitylaminopyrimidine (doarap) and 6,7-dimethyl-8-ribityllumasine occurs in the riboflavin-deficient mutants divided into five biochemical groups. this fact evidences for iden ...1975834
[mechanism of retroinhibition in e regulation of flavinogenesis in yeasts of genus pichia].the kinetics of the synthesis of a riboflavin (rf) precursor, 2,6-dihydroxy-5-amino-4-ribitylaminopyrimidine (dharap), was studied using the washed cells of rf-deficient mutants of pichia guilliermondii r7g and pichia ohmeri r32 with blocked lumasine synthetase. rf inhibited the synthesis of dharap while cycloheximide in the absence of rf had no effect on this process. the data suggest that flavins regulate the biosynthesis of rf in p. guillier mondii and p. ohmeri b7 means of feed-back inhibiti ...19751160631
[protoplast formation and cell degradation of n-alkane-grown candida guilliermondii and candida spec]. 19751189471
[study of the regulation of the synthesis and activity of imp-dehydrogenase in the yeast pichia guilliermondii].activity of imp-dehydrogenase was studied in the cells of p. guilliermondii atcc 9058 from different growth phase; the yeast was cultivated in iron-rich and iron-deficient media. the highest activity of the enzyme was found in the iron-rich cells from the logarithmic growth phase. in the iron-deficient cells synthetizing great amounts of riboflavin the imp-dehydrogenase activity was somewhat higher in negative growth acceleration phase than that of iron-rich cells from the same stage. guanine co ...19751202696
[effect of urea and amino acids of the ornithine cycle on the biomass accumulation and amino acids synthesis by candida guilliermondii].when assimilating urea, arginine, ornithine and citrulline as the sole source of nitrogen, c. guilliermondii shows a higher economic coefficient of biomass accumulation (54.2, 59.7, 40.6% respectively) as compared with ammonium sulphate whose coefficient is 35.6%. nitrogen sources exert a significant influence on the content of essential amino acids in the alcohol soluble fraction of cell biomass. for instance, urea and arginine are responsible for the accumulation of ornithine (220 and 480 mug/ ...19751208387
specific p-nitrophenyl phosphatase of yeast pichia guilliermondii.the cells of yeast p. guilliermondii contain specific p-nitrophenyl phosphatase (pnppase), the level of which depends on the cells supply with inorganic phosphorus. partially purified enzyme is activated by ions mg2+, co2+ and somewhat weaker -- by ions fe2+. with the presence of mg2+ the enzyme activity is inhibited by ions cd2+, zn2+, f-, be2+, cu2+, mn2+, ca2+, moo42-, fe3+, fe2+, inorganic phosphate as well as by edta. a mixture ions be2+ and f- causes a complete inhibition of the activity. ...19751885
[determination of the relative volume of the incorporations of a lipid nature by candida guilleirmondii yeast cultured on hydrocarbons].the paper describes a method for measuring a relative volume of lipid incorporations into yeast candida guilliermondii cultivated on hydrocarbons. a relative volume of the incorporations (mean ratio of the volume of lipid incorporations to the cell volume expressed as percentage) as compared with the hydrocarbon content in the cells expressed as percentage of the yeast dry weight is given for each yeast sample. a direct correlation between the hydrocarbon content and relative volume of lipid inc ...1975171643
[activity of certain dehydrogenases in accumulation and continuous-flow culture of paraffin-oxidizing yeast of the genus candida].lability of nadp- and nad-dependent glutamate dehydrogenases and malate dehydrogenases has been demonstrated during a change of the physiological activity of yeast candida guilliermondii in the exponential phase of growth. variations in the isoenzyme spectrum of the enzymes and total dehydrogenase activity of the yeast has been found during their transition from the accumulative to the continuous cultivation. changes in the physiological state of yeast during their growth are accompanied by a re ...1975241990
[enzynatic method of disrupting yeast cell walls].the influence of the preparation of mucolytic enzymes obtained from the culture liquid filtrate of actinomyces griseinus on the yeast candida guilliermondii was investigated. lipids, hydrocarbons and proteins were extracted and free amino acids were separated from the biomass made of disrupted yeast cells. the extract contained 73% of cytoplasmic substances whereas normal yeast (enzymically untreated) contain on the average 13.7%. lipids and hydrocarbons were measured.19751208420
[effect of magnesium concentration in the culture medium on the trace element requirement of yeasts].the effect of different magnesium concentrations in the culture liquid (ranging from 2=6 to 220 mg/l) on the accumulation of mg and mn ions in the yeast candida guilliermondii was studied during their continuous cultivation on purified liquid paraffins. a reverse correlation between the accumulation of magnesium and manganese in the yeast biomass was established. the magnesium content in the biomass increased with an increase of its concentration in the nutrient medium. the biomass yield was opt ...19751208428
[flavinogenesis and regulation of purine biosynthesis de novo in pichia guilliermondi mutants resiatant to 8-azaguanine].93 mutants resistant to 8-azaguanine (agr-mutants) were derived from the strain of pichia guilliermondii with blocked guanine deaminase (ec 3.5.4.3.) by uv-irradiation. the mutants retained the ability to uptake 8-azaguanine and guanine but could not deaminate guanine. some of the agr-mutants were found to accumulate large amounts of hypoxanthine and small amounts of guanine in the cultural medium. the inhibitory effect of guanine and 8-azaguanine but not adenine on the purine biosynthesis de no ...19751218707
[increased flavin synthesis in yeasts utilizing hydrocarbons].comparative studies of the process of possible overproduction of flavins by cultures with different flavinogenous activity grown on media with hydrocarbons and glucose have been carried out. the strains with a high flavinogenous activity, candida guilliermondii and torulopsis famata o-3, produced more flavins on media containing hydrocarbons than the cultures with a low flavinogenous activity. at a high content of iron in the medium, which is unfavourable for overproduction of riboflavin the rat ...19751239655
[participation of flavins and iron in regulating the rate of the 1st flavinogenesis reaction in pichia guilliermondii yeasts]. 19761248355
[effects of light shielding and reversible inactivation of candida guilliermondii, induced by 313 nm light]. 19761269401
[on the similarity of antigen between fungi and salmonella. 4. communication (author's transl)].the immune sera for candida membranefaciens (c. majoricensis), candida guilliermondii var. carpophila, metschnikowia bicuspidata, syringospora stellatoidea and torulopsis candida agglutinated salmonella cholerae-suis (6,7). the immune serum for s. cholerae-suis agglutinated candida membranefaciens (c. majoricensis), candida guilliermondii var. carpophila, metschnikowia biscuspidata, syringospora stelladoidea and torulopsis candida. absorption and agglutination cross test demonstrated common anti ...197665072
[excretion of organic compounds bei microorganisms in presence of diphenylamine].diphenylamine (dpa) causes an increased leakage of organic compounds with resting cells of candida guilliermondii, bacillus subtilis, escherichia coli, and staphylococcus aureus already after a treatment of 1 h. the leakage depends both on the concentration of dpa and the duration of the treatment. moreover, dpa influences the composition of the leaked ninhydrine-positive compounds. after 20 h of treatment an increased release of mannan and ribose is observed in addition to the stronger leakage ...1976823713
defective neutrophil function in chronic granulocytic leukaemia.the ability of neutrophils to phagocytose, kill and digest candida guilliermondii was investigated in twelve patients with chronic granulocytic leukaemia (cgl). following ingestion of organisms there was considerable reduction in the ability of cgl cells to kill candida and this was not explained by a mild impairment of phagocytosis. histochemical staining showed that granules containing lysosomal enzymes disappear form the cytoplasm of normal neutrophils during killing and digestion of the fung ...197660123
biosynthesis of beta-phenethyl alcohol in candida guilliermondii. 197657780
regulation of 6-hydroxy-2,4,5-triaminopyrimidine synthesis by riboflavin and iron in riboflavin-deficient mutants of pichia guilliermondii yeast.the effect of riboflavin and iron on 6-hydroxy-2,4,5-triaminopyrimidine synthesis rate was investigated in the cultures of the yeast pichia guilliermondii (rib2 mutants) with the blocked second reaction to flavinogenesis. it was shown that riboflavin inhibited the 6-hydroxy-2,4,5-triaminopyrimidine synthesis rate in iron-rich and iron-deficient cells of mutants with low riboflavin requirements. cycloheximide did not prevent the stimulation of 6-hydroxy-2,4,5-triaminopyrimidine synthesis caused b ...19766053
[a flavinogenic mutant of the yeast pichia guilliermondii with impaired iron transport].a mutant of the yeast pichia guilliermondii was produced by means of uv; the mutant was capable of riboflavin overproduction in the presence of high concentrations of iron in the medium. the content of total and non-hemin iron and cytochrome c, and the activity of catalase, were lower in the cells of the mutant than in the parent cells, while the activity of riboflavin synthetase was higher. the content of iron in the cells increased when the mutant was cultivated on media with citric acid, side ...1976933879
phytochrome system of the yeast candida guilliermondii and recovery from ultraviolet injury.the effect of red (660 nm) and far-red (730 nm) light on the stability of the yeast candida guilliermondii to lethal u.v. radiation has been studied. reactivation and protection were exhibited for 30 min after treatment with red light and were abolished by far-red exposure applied within this time period. the temperature dependence of the reactivation effect was also studied. the data obtained showed that the properties of recovery and protection against u.v. exposure are associated with the phy ...1976956776
[changes in the polysaccharide biosynthesis of candida guilliermondii induced by diphenylamine].diphenylamine (dpa) inhibits the formation of glucan in candida guilliermondii while stimulating that of mannan. the total polysaccharide of cells decreases when growing in the presence of dpa. these effects are dependent on the concentration of dpa. compared with 14 structure-like substances, dpa was found to have the strongest activity.1976969574
[localization of ubiquinone-9 in electron transport chain of candida guilliermondii].the activity of ubiquinone-dependent enzyme systems was studied in mitochondrial fractions of the yeast candida guilliermondii cultivated on the medium containing carbohydrates of hydrocarbons as a source of carbon. the activity of nadh2-oxidase and succinate-coq-reductase was higher in systems with mitochondrial fractions from the cells grown on the medium with n-paraffins than in mitochondrial fractions from the cells cultivated on the medium with glucose. about 30% of intracellular ubiquinone ...19761004242
bovine vesiculitis and epididymitis due to feed contamination by candida guilliermondii. 19761036341
[detection in pichia guilliermondii of gtp-cyclohydrolase, an enzyme involved in the 1st stage of flavinogenesis]. 1976976065
study of acid phosphatase ii from pichia guilliermondii yeasts.acid phosphatase ii (ap ii) was isolated from the cell-free extract of pichia guilliermondii wickerham atcc 9058 and partially purified. the enzyme is a non-specific phosphomonoesterase. it hydrolyzes p-nitrohenyl-phophate (npp), beta-glycerophosphate, glucose-6-phosphate, guanosine-5'-monophosphate, adenosine-5'-monophosphate, cytidine-5'-monophosphate, uridine-5'-monophosphate, alpha-naphtylphosphate, fmn. the order of the substrates corresponds to the degree of their hydrolysis decrease. the ...19768863
purification and properties of the riboflavin kinase of the yeast pichia guilliermondii.riboflavin kinase (e.c.2.7.1.26) was isolated from the cells of the yeast pichia guilliermondii. the enzyme was 680-fold purified uzing ammonium sulphate fractionation, chromatography on deae-sephadex a-50 and cm-sephadex c-50 and gel-filtration through sephadex g-75. purified enzyme preparation was free from phosphatases and fad-synthetase. the ph optimum was 8,7, the temperature optimum-45 degrees c. the enzyme was activated by zn2+, mg2+ and co2+ ions. km for riboflavin was 1,0x10(-5) m, for ...19766079
[alterations in the excess synthesis of riboflavin in pichia guilliermondii under the influence of branched-chain amino acids].the effect of the branched-chain amino acids: l-valine, l-isoleucine and l-leucine on riboflavin overproduction was studied in the pichia (candida) guilliermondii (cast.) lang. et g. yeast, l-val, l-ile and l-leu were found to inhibit riboflavin overproduction only under iron-deficient growth conditions. other amino acids used did not show this effect. in crude extracts of p. guilliermondii the specific activity of the alpha-acetolactate forming enzyme, ph 8.0, is inhibited by l-val. it is revea ...1977867527
[influence of carbon source on lipid biosynthesis by candida gluilliermondii].the biosynthesis of lipids by candida guilliermondii was studied during the growth of the yeast on carbon substrates which resulted in different pathways of lipid biosynthesis. the highest content of lipids was found during the growth on octadecane. the quantitative ratio between fractions of neutral lipids and phospholipids depended on the carbon substrate whereas the quanlitative composition of the fractions remained the same. the fatty acid composition of lipid fractions was studied, and poss ...1977882010
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