Publications

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on the formation of carthamin in the flowers of carthamus tinctorius. 195513229360
influence of a safflower oil emulsion on serum cholesterol level. 195713472575
the hexose monophosphate shunt as the major respiratory pathway during sporulation of rust of safflower. 195716654941
comparison of effects of x-rays and thermal neutrons on dormant seeds of barley, maize, mustard, and safflower. 195817247791
effect of safflower oil emulsion on serum cholesterol levels in young adult males; its use as a supplement to a normal diet. 195813525187
response of serum lipids and lipoproteins o man to beta-sitosterol and safflower oil; a longterm study. 195813537276
effect of safflower oil on serum cholesterol and lipoproteins in patients on a low-fat diet. 195813562473
the result of treatment of hypercholesterolemia associated with atherosclerosis with sitosterol and safflower oil derivatives. 195813564045
safflower oil-pyridoxine and corn oilpyridoxine emulsions; their effect on serum cholesterol levels in young adult males when used as supplements to a normal diet. 195913640926
safflower oil. 195913640967
regression studies with safflower oil and sitosterol in rabbit atherosclerosis. 195914422548
comparison of the treatment of hypercholesteremia with nicotinic acid, sitosterol, and safflower oil. 195913799273
the effect of safflower oil on blood lipid and protein levels in glycogen storage disease of the liver. 196013839150
treatment of hypercholesterolemic patients with niacin, sitosterol and safflower oil. 196013858018
comparison between the effects of pork fat and safflower oil on serum lipids and atherosclerosis in cholesterol-fed chickens. 196014427198
effect of safflower and coconut oils upon plasma cholesterol and lipid fractions. 196014428532
the effect of safflower oil on serum lipids. 196014438294
the effect of safflower oil on the nature of serum cholesterol esters. 196013792624
studies on the nutritional aspects of hydrogenated tobacco seed and safflower seed oils. 196114448662
plasma fibrinolysis in man: the effect of chylomicrons derived from different dietary fats.the plasma fibrinolytic activity, measured in vitro, of 17 healthy normal young males was consistently and equally inhibited by prior ingestion of equal amounts of either a relatively saturated animal fat (butterfat) or a highly unsaturated vegetable fat (safflower oil). this effect was further studied by the addition of purified chylomicrons derived from ingestion of either butterfat, safflower oil, or egg yolk to an in vitro system. the inhibitory effect was quantitatively similar in all exper ...196113698247
the effect of safflower oil upon serum lipids and proteins in juvenile diabetes mellitus. 196113777834
safflower: utilization and significance in nutrition and allergy. 196414104253
synthesis of linoleic acid by particulate system from safflower seeds. 196414196780
cholesterol metabolism. 3. enhancement of cholesterol absorption and accumulation in safflower oil-fed rats. 196414233150
utilization of safflower meal by the chick and its effect upon plasma lysine and methionine concentrations. 196514344018
effects of vitamin b6 and safflower oil on dietarily induced hyperlipemia and fat in the liver of rats. 19655859679
fat metabolism in higher plants. xxvi. biosynthesis of fatty acids in tissues of developing seeds and germinating seedlings of safflower (carthamus tinctorius l.).the capacity of both developing seeds and germinating seedlings of safflower for the incorporation of acetate-c(14) into long-chain fatty acids is examined. intact tissue of the developing seed shows a low rate of acetate incorporation into fatty acid initially but between the tenth and twenty-fifth day after flowering the tissue has a high rate of synthesis, in particular with respect to the unsaturated fatty acids. centrifuged fractionation of homogenates of this developmental tissue yielded s ...19665904587
the status of safflower. 19665934266
the composition of safflower seed. 19665934267
safflower meal. 19665934268
the role of safflower oil in edible oil applications. 19665934269
high oleic acid safflower oil: a new stable edible oil. 19665938124
a note on the anticholesterol activity of safflower oil. 19665942500
desaturation of fatty acids in seeds of higher plants.photosynthesizing flax, soybean, and safflower plants were exposed to (14)co(2) at seed-setting stage for a 1 hr period. seed was sampled periodically thereafter and the lipids were extracted. a triglyceride-rich fraction was methanolyzed; the resultant methyl esters were analyzed by gas-liquid chromatography and assayed for radioactivity. of the c(18) unsaturated acids, oleic was the first to acquire radioactivity, which subsequently and successively appeared in linoleic and linolenic acids. th ...19665949952
influence of diet on the composition of plasma cholesterol esters in man.the effect on the plasma cholesterol esters of diets rich in either carbohydrate, chocolate, or safflower oil was studied sequentially in two men. the changes in the cholesterol esters of the major plasma lipoproteins were studied by measuring (a) the distribution of fatty acids in the esters and (b) the distribution of radioactivity among the esters after the administration of cholesterol-4-(14)c labeled lipoproteins. similar changes were found in the cholesterol esters of the two major lipopro ...19665965292
a radioautographic study of glyceride synthesis in vivo during intestinal absorption of fats and labeled glucose.radioautography was used to detect the synthesis of labeled glycerides in intestinal absorptive cells following injections of fatty chyme and glucose-6-h(3) into ligated segments of upper jejunum of fasting rats. absorption intervals ranged from 2 to 20 min. labeling is evident throughout the cells in as short a time as 2 min. most grains are present over droplets of absorbed fat beginning with those in the endoplasmic reticulum immediately subjacent to the terminal web. with longer absorption p ...19665971642
preparation of pure methyl esters by counter double current distribution.counter double current distribution with continuous stills for solvent and product recovery and an acetonitrile-hexane solvent system is a convenient method for preparative isolation of individual fatty methyl esters. preparations of pure methyl linoleate from safflower esters and a methyl arachidonate concentrate from hog liver lipids are described.196617805605
determination of the structure of lecithins.a method is described for the determination of the classes of lecithins in terms of unsaturated and saturated fatty acids based on a total fatty acid composition, the composition of the fatty acids in the beta-position, and the amount of disaturated class determined via mercuric acetate adduct formation. the accuracy of the method was determined on lecithins of known composition and the method was applied to lecithins isolated from milk serum and egg lipids, safflower and soybean oils.196617805667
determination of the structure of lecithins via the formation of acetylated 1,2-diglycerides.a detailed procedure for quantitative determinations of molecular species of lecithins is described and applied to several lecithins isolated from natural sources. the method is based on the conversion of lecithin to acetylated 1,2-diglycerides and analysis of these compounds by methodology used for the determination of triglyceride structure.the preparation of the acetylated 1,2-diglycerides was carried out via hydrolysis with phospholipase c and acetylation of the resultant, 1,2-diglycerides w ...196717805742
dietary fat and cholesterol and serum cholesterol in the gerbil.groups of gerbils were fed purified diets containing either 10 or 20% of safflower, olive, or coconut oil. each diet was fed without cholesterol and with 0.1 and 0.2% of added cholesterol. the animals were bled after 2, 4, and 8 wk for the determination of the level of serum cholesterol. the major factors affecting the level of serum cholesterol were the kind of dietary oil, the amount of dietary cholesterol, and the length of time the diet was fed. the level of safflower oil had a statistically ...19676038560
high-oleic safflower oil. stability and chemical modification. 19676041386
effects of dietary safflower oil or hydrogenated coconut oil on growth rate and on some blood and tissue components of pigs fed a fat-free diet. 19676053737
fatty acid changes in liver and plasma lipid fractions after safflower oil was fed to rats deficient in essential fatty acids.1. fatty acid patterns of liver and plasma triglycerides, phospholipids and cholesteryl esters were determined at intervals during 24hr. after essential fatty acid-deficient rats were given one feeding of linoleate (as safflower oil). 2. liver triglyceride, phospholipid and cholesteryl ester fatty acid compositions did not change up to 7hr. after feeding. between 7 and 10hr., linoleic acid began to increase in all fractions, but arachidonic acid did not begin to rise in the phospholipid until 14 ...19676056631
effect on serum cholesterol of the rat, of feeding pig depot fat after the ingestion of safflower oil. 19676063224
nutritional value of safflower meal. 19675341519
microreactor for methanolysis of triglycerides before gas-liquid chromatography.a rapid, accurate microtechnique has been developed for gas chromatographic determination of the fatty acid composition of small (2-3 micro l) samples of vegetable oils. this microtechnique combines transesterification and sample injection into a single operation. the fatty acid compositions of soybean, linseed, and safflower oils thus determined are compared with those obtained by the usual two-step procedure.196714564723
color problems in oils from experimental safflower varieties. 19685640218
failure of safflower oil hyperlipemia to inhibit limitation of the size of experimental streptokinase-treated myocardial infarction. 19685649441
effect of dietary fat on the fecal excretion of cholesterol and its degradation products in man.fecal bile acid and neutral sterol excretion rates were determined in five healthy young men when serum cholesterol changes were induced by isocaloric substitution of an unsaturated (safflower oil) for a saturated fat (butter). the isotope balance method was used after the intravenous injection of cholesterol-4-(14)c. a feces extraction method is presented which permits essentially complete separation of fecal neutral sterols and bile acids. there was a significant increase in the total excretio ...19685658585
lipid composition of the isolated rat intestinal microvillus membrane.1. rat intestinal microvillus plasma membranes were prepared from previously isolated brush borders and the lipid composition was analysed. 2. the molar ratio of cholesterol to phospholipid was greatest in the membranes and closely resembled that reported for myelin. 3. unesterified cholesterol was the major neutral lipid. however, 30% of the neutral lipid fraction was accounted for by glycerides and fatty acid. 4. five phospholipid components were identified and measured, including phosphatidyl ...19685669848
effect on serum cholesterol of the rat of feeding pork processed goods by safflower oil. 19685674438
a comparative study of hypocholesterolemic activity of lipid extract of bengal gram with safflower oil, mustard oil and ground-nut oil in albino rats. 19685711604
safflower meal--utilization as a protein source for broiler rations. 19685749590
differential responses to fasting and subsequent feeding by microsomal systems of rat liver: 6- and 9-desaturation of fatty acids.hepatic microsomal preparations from nonfasted, fasted, and fasted-fed rats were employed, together with cofactors, in studies of 9-desaturation of stearate-1-(14)c and 6-desaturation of linolenate-1-(14)c. prior fasting sharply reduced 9-desaturation but did not affect 6-desaturation; feeding restored 9-desaturation. position of desaturation was determined by permanganate-periodate oxidation and separation of the dicarboxylic acids. feeding after fasting stimulated both desaturase systems but e ...19694306613
countercurrent distribution of inosol lipids of plant seeds.the inositol lipids of plant seeds consist of phosphatidyl inositol, the phytoglycolipids, and a previously uncharacterized ceramide-phosphate-polysaccharide. these three species have been separated from each other and from the common glycerophosphatides by a series of simple countercurrent distributions, first as the naturally occurring ca-mg salts and subsequently in the na salt form. the new ceramide-phosphate-polysaccharide is present in each of the four plant phosphatides examined (corn, so ...19694307829
an antifungal polyacetylene compound from phytophthora-infected safflower. 19705417760
[safflower oil]. 19715099473
fat metabolism in higher plants. xlvi. nature of the substrate and the product of oleyl coenzyme a desaturase from carthamus tinctorius. 19715102929
comparative feeding value of groundnut oil meal and safflower oil meal in chick rations. 19715103628
fat metabolism in higher plants. 48. properties of oleyl coenzyme a desaturase of carthamus tinctorius. 19724333259
fatty acid interrelationships in plasma, liver, muscle and adipose tissues of cattle fed safflower oil protected from ruminal hydrogenation. 19725012341
the incorporation of linoleic acid into the tissues of growing steers offered a dietary supplement of formaldehyde-treated casein-safflower oil. 19725017906
formation of lymph chylomicron phosphatidylcholines in the rat during the absorption of safflower oil or triolein. 19725037151
formaldehyde-treated casein-safflower oil supplement for dairy cows. i. effect on milk composition. 19725065670
formaldehyde-treated casein-safflower oil supplement for dairy cows. ii. effect on the fatty-acid composition of plasma and milk lipids. 19725065671
the dry socket--a new lubricant (safflower oil). 19734574562
alcohol dehydrogenase allozymes in the safflower genus carthamus l. 19734732521
biological effects of autoxidized safflower oils. 19734750535
the utilization by growing lambs of a casein-safflower oil supplement treated with formaldehyde. 19734764241
nutritional evaluation of heated safflower oil in the rat. 19734787499
influence of abomasally administered safflower oil on fat composition and organoleptic evaluation of bovine tissue. 19744823198
fat metabolism in higher plants. properties of a soluble stearyl-acyl carrier protein desaturase from maturing carthamus tinctorius. 19744831331
effect of amount and frequency of feeding safflower oil on related milk, blood, and rumen components. 19744413020
nutritional properties of a fraction separated from heated safflower oil. 19744427466
steroid balance and tissue cholesterol accumulation in germfree and conventional rats fed diets containing saturated and polyunsaturated fats.steroid balance studies were conducted on 24 conventional and 12 germfree male rats, 90-120 days old, fed diets containing either 20% safflower or 20% coconut oil. both germfree and conventional rats fed the safflower oil diets had significantly lower serum cholesterol levels and significantly higher liver cholesterol levels than did the rats fed coconut oil. no significant differences in total fecal neutral sterols, coprostanol, delta(7)-cholestenol, or total fecal bile acid excretion were seen ...19744430880
effects of abomasal infusions of safflower oil or elaidic acid on blood lipids and milk fat in dairy cows. 19744443461
fat metabolism in higher plants. properties of the palmityl acyl carrier protein: stearyl acyl carrier protein elongation system in maturing safflower seed extracts. 19744153356
fat metabolism in higher plants: lxii. stearl-acyl carrier protein desaturase from spinach chloroplasts.stearyl-acyl carrier protein desaturase (ec 1.14.99.6), present in the stroma fraction of spinach (spinacia oleracea) chloroplasts, rapidly desaturated enzymatically prepared stearyl-acyl carrier protein to oleic acid. no other substrates were desaturated. in addition to stearyl-acyl carrier protein, reduced ferredoxin was an essential component of the system. the electron donor systems were either ascorbate, dichlorophenolindophenol, photosystem i and light, or nadph and ferredoxin-nadp reducta ...197416658913
evaluation of the germ plasm collection of safflower carthamus tinctorius l. vi. length of planting to flowering period and plant height in israel, utah and washington.germ plasm collections of safflower, carthamus tinctorius l. were evaluated for variability and divergence in two traits which are strongly influenced by the environment, viz. length of the growing period from planting to flowering (gppf) and plant height. the test locations were: bet-dagan, israel, 1969, about 2000 lines; logan, utah, usa, 1964, about 1000 lines; washington, usa, 1959, 339 lines. natural selection produced a wide range of variation for length of the gppf: there were considerabl ...197524420178
glucogenic and ketogenic capacities of lard, safflower oil, and triumdecanoin in fasting rats.the glucogenic and ketogenic capicities of lard, safflower oil, and triundecanoin were compared. rats were fed diets containing 30 percent of either lard (a ketogenic fat), triundercanoin (a glucogenic fat), or safflower oil (a fat high in linoleic acid). after 61 days, the rats were fasted for 72 hours. plasma glucose and ketone body concentrations and carcass fatty acid loss were measured during fasting. the lard-fed animals, which lost mostly saturated even-chain length fatty acids during fas ...19751113198
growth, blood parameters and tissue lipids of finishing cattle fed a formaldehyde treated casein-safflower oil complex. 19751116971
autoxidation in milk rich in linoleic acid. i. an objective method of measuring autoxidation and evaluating antioxidants.autoxidation was studied in milk obtained from cows fed on formaldehyde-treated casein-safflower oil supplement. the fat of this milk contained high levels of linoleic acid. a rapid disappearance of dissolved oxygen (do), measured by using a oxygen electrode, from milk samples stored at 0 degrees c in tubes without head-space, coincided with the development of oxidized flavours detected organoleptically. a correlation coefficient of 0.9 with 69 degrees of freedom (p smaller than 0.001) was obtai ...19751123470
effect of dietary safflower oil upon lipogenesis in neonatal lamb.the effect of dietary safflower oil upon lipogenesis has been investigated in neonatal lambs. preliminary experiments with lambs suckled by their mothers showed that there was a 10-fold increase in the rate of incorporation of [14-c] from acetate into fatty acids in adipose tissue slices during the first 10 days post partum. barely detectable rates of [14-c] acetate incorporation into fatty acids were found in liver slices from lambs during the same period. in lambs given cows' milk from birth u ...19751128174
effect of feeding polyunsaturated fatty acids with a low vitamin e diet on blood levels of tocopherol in men performing hard physical labor.a diet made low in vitamin e by elimination of foods considered good sources of the vitamin was fed for 13 months to two groups of men engaged in strenuous labor. with a daily average dietary intake of about 9.4 mg of total tocopherols, a progressive decline in blood levels of tocopherol from 1.42 to 0.81 mg/100 ml was observed in the five control subjects. the test group of 30 men received a daily supplement of tocopherol-stripped safflower oil containing 88 g of polyunsaturated fatty acids and ...19751146722
influence of dietary fat upon rats during gestation and lactation.a comparison was made between rats fed purified rations containing different fats during gestation and lactation and rats fed a commercial ration during similar periods. the purified ration containign 20% cocoa butter did not result in appreciable differences in the mothers (body weight, behavior, litter production, and brain chemistry) or in the 1-day-old neonates (brain chemistry). the purified ration containing 20% safflower oil resulted in fewer completed gestation, in poorer maternal behavi ...19751147333
influence of maternal dietary fat upon rat pups.mother rats were fed purified rations containing different fats during gestation and lactation and at 1 day after parturition. litter sizes were reduced to 2 male and 2 female pups. the behavior and the brain chemical composition of these selected pups were compared with similarly selected pups from dams fed a commercial ration. all offspring were fed a commercial ration after weaning. pups from dams fed 20% safflower oil were similar to controls. feeding 20% cocoa butter to dams resulted in pup ...19751147334
temporal relationships between dietary, plasma, hepatic, and adipose tissue lipids after short-term feeding of safflower oil to rats.the objectives of this research were to study effects of dietary neutral fat on the concentration and the fatty acid composition of triglyceride (tg) and other lipid classes in plasma, liver, and adipose tissue and, particularly, to study the temporal and precursor-product relationship among those various lipid pools. accordingly, male rats were administered 1.5 ml. of safflower oil by gastric intubation at 0, 4, and 8 hours after a 16-hour fast. samples of plasma, liver, and adipose tissue were ...19751151156
effect of exogenous polyunsaturated fatty acids on lipogenic enzyme activity in rat liver under fixed carbohydrate consumption.studies were conducted to evaluate specific dampening of hyperlipogenesis (i.e. enhanced lipogenic enzyme activity of the liver in rats refed a high carbohydrate, fat-free diet: f-diet) by exogenous polyunsaturated fatty acids under fixed carbohydrate consumption. in force-feeding of rats with a linoleate-rich diet (f-diet containing 4.5% safflower oil), the lipogenic enzyme activities; fatty acid synthetase (fas) and malic enzyme (me) in the liver supernatant were found to be significantly lowe ...19751151500
influence of dietary lipids on iron and copper levels of rats administered oral contraceptives.interrelationships between oral contraceptives and dietary lipids on iron and copper levels in plasma and tissues were investigated in rats. diets containing either 20% (by weight) safflower oil or hydrogenated coconut oil with and without cholesterol (0.5%) were fed to weanling, female, wistar-strain rats for a period of 19 weeks. three types of oral contraceptive agents differing in estrogen/progesterone ratios were administered during weeks 16 through 19 of the experiment. control rats receiv ...19751159520
vitamin e adequacy of vegetable oils.young male rats were fed diets containing 20 per cent fat in the form of soybean oil, corn oil, safflower oil, or hydrogenated shortening, and their vitamin e status was assessed for twenty-seven weeks. on the basis of growth rate, in vitro red cell hemolysis, plasma creatine phosphokinase activity, and testicular development, soybean oil, corn oil, and shortening provided adequate vitamin e. rats fed safflower oil had slight red cell hemolysis but were normal in other respects. when the tocophe ...19751167555
biosynthesis of saturated and unsaturated fatty acids by maturing carthamus tinctorius l. seeds. 19751184911
rat brain fatty acid composition: effect of dietary fat and age.the polyunsaturated fatty acid composition of human brain changes, as well as progressively decreases, with age. to determine if whole brain rat lipid shows similar changes with age, rats born to mothers fed semi-synthetic diets were raised on the same diet as their mothers for varying periods prior to sacrifice. whole brain lipid composition was determined for female offspring, fed diets containing 20% w (by weight) of either lard or safflower oil, from age 6 days to 730 days. the percentage of ...19751184922
influence of dietary safflower oil and tallow on growth, plasma lipids and lipogenesis in rats, pigs and chicks.rats, chicks and pigs were fed diets containing safflower oil or tallow. plasma triglyceride levels were elevated when tallow, rather than safflower oil was added to the diet of rats, unchanged in chicks and lowered when tallow, rather than safflower oil was fed to pigs. the rate of fatty acid synthesis in rat and chick liver was higher, whereas the rate of lipogenesis in adipose tissue preparations from rats and pigs was lower when tallow, rather than safflower oil was fed. these results indica ...19751208547
the effect of vaginal lubricants on sperm motility in vitro.apart from the documentation of the spermicidal effects of ky jelly and surgilube, little information about the effect of vaginal lubricants on sperm motility has been available. fifteen substances utilizable as vaginal lubricants were therefore tested for their effect on sperm motility in vitro. petroleum jelly and glycerin had minimal detrimental effects on motility and apparently are the lubricants of choice when an infertility problem exists.19751237417
effects of dietary triglyceride on the properties and lipid composition of plasma lipoproteins: acute experiments in rats fed safflower oil.male rats were administered 1.5 ml safflower oil by gastric intubation 0, 4, and 8 hr after a 16 hr fast. plasma, liver, and adipose tissue were collected 16 hr after the last fatty meal. rats fasted for 16 hr served as controls. following fat feeding, the fatty acid composition of the very low density lipoprotein, triglyceride, and hepatic triglyceride were similar, as were the percentages of 18:2 in the very low density lipoprotein and hepatic cholesteryl esters. the phospholipids of liver and ...1975173964
essential fatty acid deficiency in four adult patients during total parenteral nutrition.four undernourished adults (15%-37% below idealll body weight) received fat-free total parenteral nutrition for a period of 6 to 8 weeks. chemical evidence of essential fatty acid deficiency (triene:tetraene ratio greater than 0.4) appeared in all patients during the first 3 weeks of treatment. deficiency developed more rapidly in the two patients who were younger (ages 16 and 36) and more severely undernourished (26% and 37% below ideal body weight) than in the two older patients (62 and 76) wh ...1975804247
evaluation of chromic oxide, glycerol triether, and beta-sitosterol as fecal flow markers in two species of nonhuman primates.recovery of beta-sitosterol, glycerol triether (1-hexadecyl-2,3-didodecyl glycerol triether), and chromic oxide was studied in african green monkeys and stumptail macaques consuming diets containing 0.75 mg/cal cholesterol and 38% of calories as safflower oil or butter. following oral administration of these compounds, feces were collected daily for 9 days. for all animals, excretion of beta-sitosterol and glycerol triether paralleled one another almost exactly. except for two animals, this was ...1975804580
depression of lecithin-cholesterol acyltransferase esterification in vitamin e-deficient monkeys.vitamin e deficiency in two species of monkeys (capuchins and cynamolgus) reduced the in vitro cholesterol esterification by plasma lecithin-cholesterol acyltransferase. the reduction was greates in the most deficient species and in animals fed a diet rich in polyunsaturated fat (safflower oil) stripped of vitamin e. the best correlate of total esterification was the plasma concentration of free cholesterol which reflected the degree of hyperlipidemia, found to be greatest in capuchins fed cocon ...1975808956
effect of type of dietary fat, cholesterol and chenodeoxycholic acid on gallstone formation, bile acid kinetics and plasma lipids in squirrel monkeys.to explore the effect of type of dietary fat, cholesterol and chenodeoxycholic acid on gallstone formation, bile formation, bile composition, bile acid kinetics and plasma lipids in squirrel monkeys, 39 monkeys were studied using seven different diets. safflower oil, a highly unsaturated fat, added to a diet with cholesterol resulted in at least as high an incidence of cholesterol gallstones as butter added to the same diet. on the other hand, diets with high levels of saturated or unsaturated f ...1976820839
free radical theory of aging: effect of dietary fat on central nervous system function.free radical reactions have been implicated in aging. a rise in the level of random free radical reactions in a biologic system might have a greater effect on the central nervous system (cns) than elsewhere, partly because of the presence of glial cells and the unique connections between neurons. to evaluate this possibility, some animal experiments were conducted. the initial experiment involved old male sprague-dawley rats fed (since shortly after weaning) with semisynthetic diets characterize ...1976932378
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