Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| new tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeutics. | despite the availability of mycobacterium tuberculosis (mtb) drugs for over 50 years, tuberculosis (tb) remains at pandemic levels. new drugs are urgently needed for resistant strains, shortening duration of treatment, and targeting different stages of the disease, especially for treatment during human immunodeficiency virus co-infection. one solution to the conundrum that antibiotics kill the bacillus yet select for resistance is to target the host rather than the pathogen. here, we discuss rec ... | 0 | 25703571 |
| induction and regulation of t-cell immunity by the novel tuberculosis vaccine m72/as01 in south african adults. | tuberculosis (tb) is a major cause of morbidity and mortality worldwide, thus there is an urgent need for novel tb vaccines. | 0 | 23306546 |
| c-type lectins with a sweet spot for mycobacterium tuberculosis. | the pattern of receptors sensing pathogens onto host cells is a key factor that can determine the outcome of the infection. this is particularly true when such receptors belong to the family of pattern recognition receptors involved in immunity. mycobacterium tuberculosis, the etiologic agent of tuberculosis interacts with a wide range of pattern-recognition receptors present on phagocytes and belonging to the toll-like, nod-like, scavenger and c-type lectin receptor families. a complex scenario ... | 0 | 24466434 |
| immune response to immunodominant mycobacterium tuberculosis antigen esat-6 derived peptide is hla-haplotype dependent. | the antigenic proteins of mycobacterium tuberculosis (mtb) have been defined. we used synthetic peptides of secreted antigens, early secreted antigenic target 6 (esat-6) and cultural filtrate protein-10 (cfp-10), of mtb and characterized the immune response in context of hla genes. humanized mice lacking endogenous class ii molecules but expressing various human dr and dq hla transgenes singly or as a haplotype were used to study the hla-mediated immune response to peptides. our observations sho ... | 0 | 25664343 |
| infectious complications after liver transplantation. | orthotopic liver transplantation (olt) is the standard of care for patients with decompensated cirrhosis and for patients with hepatocellular carcinoma. more than 6000 liver transplants are performed annually in the united states. high patient and graft survival rates have been achieved in great part due to the availability of potent immunosuppressive agents. systemic immunosuppression has rendered the liver recipient susceptible to de novo infections as well as reactivation of preexisting laten ... | 0 | 27134589 |
| therapeutic effect of farnesylthiosalicylic acid on adjuvant-induced arthritis through suppressed release of inflammatory cytokines. | rheumatoid arthritis (ra) is an autoimmune disease characterized by pronounced inflammation and leucocyte infiltration in affected joints. despite significant therapeutic advances, a new targeted approach is needed. our objective in this work was to investigate the anti-inflammatory effects of the ras inhibitor farnesylthiosalicylic acid (fts) on adjuvant-induced arthritis (aia) in rats, an experimental model for ra. following aia induction in lewis rats by intradermal injection of heat-killed m ... | 0 | 24215151 |
| collagen-induced arthritis: a model for murine autoimmune arthritis. | collagen-induced arthritis (cia) is a common autoimmune animal model used to study rheumatoid arthritis (ra). the development of cia involves infiltration of macrophages and neutrophils into the joint, as well as t and b cell responses to type ii collagen. in murine cia, genetically susceptible mice (dba/1j) are immunized with a type ii bovine collagen emulsion in complete freund's adjuvant (cfa), and receive a boost of type ii bovine collagen in incomplete freund's adjuvant (ifa) 21 days after ... | 0 | 26539560 |
| standardization of an experimental model suitable for studies on the effect of exercise on arthritis. | to standardize an experimental model of chronic monoarthritis induced by complete freund's adjuvant appropriate for the analysis of the effect of walking on nociception and on joint edema. | 0 | 23579748 |
| effect of honey bee venom on lewis rats with experimental allergic encephalomyelitis, a model for multiple sclerosis. | multiple sclerosis (ms) is a progressive and autoimmune neurodegenerative disease of the central nervous system (cns). this disease is recognized through symptoms like inflammation, demyelination and the destruction of neurological actions. experimental allergic encephalomyelitis (eae) is a widely accepted animal model for ms. eae is created in animals by injecting the tissue of myelin basic protein (mbp), cns, or myelin oligodendrocyte glycoprotein (mog) along with the adjuvant. eae and ms are ... | 0 | 24250492 |
| tuberculosis-associated death among adult wild boars, spain, 2009-2014. | we investigated adult eurasian wild boar (sus scrofa) survival and death in 2 tuberculosis-endemic populations with different harvest pressure in spain. overall, tuberculosis accounted for 30% of total deaths. increased survival in protected areas has direct implications for wild boar management and tuberculosis control. | 0 | 27869587 |
| some remarks on ehrlich and gibbes's methods for the detection of bacillus tuberculosis. | 1882 | 20750357 | |
| a new stain for bacillus tuberculosis. | 1898 | 19600816 | |
| the branched form of the bacillus tuberculosis in sputum. | 1898 | 19866876 | |
| on the action of some essential oils and other volatile substances on the growth of the bacillus tuberculosis and in the treatment of phthisis. | 1899 | 20758290 | |
| bio-chemical studies on the bacillus tuberculosis. | 1901 | 19971409 | |
| a study of the variation in virulence of the bacillus tuberculosis in man: (abstract presentation.). | 1901 | 19971411 | |
| observations on the morphology of bacillus tuberculosis from human and bovine sources. | 1903 | 19971576 | |
| report of committee on bacillus tuberculosis in man and animals. | 1903 | 19601142 | |
| studies on tuberculous serums and the bacteriolysis of bacillus tuberculosis. | 1904 | 19971636 | |
| on the bio-chemistry of the bacillus tuberculosis: second communication. | 1904 | 19971640 | |
| report of the committee on the bacillus tuberculosis in man and animals. | 1905 | 19601162 | |
| the growth of the bacillus tuberculosis and other micro-organisms in varying percentages of oxygen. | 1909 | 16742138 | |
| the function of the spleen in the experimental infection of albino mice with bacillus tuberculosis. | infection of rats and mice with bacillus tuberculosis (bovine type) develops a splenic tumor as a typical lesion. removal of the spleen from mice (albino) greatly increases their resistance to the infection. this increased resistance cannot be explained at present. the infection in the splenectomized mice tends to remain localized as contrasted with an almost septicemic type of disease which is usual in the normal animal. the animals of each group that live more than thirty days are apt to prese ... | 1914 | 19867757 |
| the function of the spleen in the experimental infection of albino mice with bacillus tuberculosis : second paper. | the resistance to an infection with the tubercle bacillus which can be given to mice by the removal of the spleen is lost when fresh spleen, either of mouse or sheep, is added to the diet. the logical conclusion that splenic function in its relation to the specific infection is restored by feeding spleen cannot, however, be drawn; because, in the first place, the character of the disease in the splenectomized spleen-fed animals differs somewhat from that in intact animals; and, secondly, because ... | 1915 | 19867852 |
| the function of the spleen in the experimental infection of albino mice with bacillus tuberculosis : third paper. | experiments are reported which show that in all probability the increased resistance to tuberculous infection which is imparted to mice by the removal of the spleen is a consequence of the loss of a function of the organ. this function can be restored by the feeding of fresh spleen. for the present we attribute these changes to the removal and restoration, as the case may be, of a particular substance for which the designation tuberculosplenatin is suggested. this substance is assumed to be rela ... | 1915 | 19867922 |
| the influence of certain organic substances on the growth of the tubercle bacillus. | the power of a large number of aniline dyes to restrain the growth of bacillus tuberculosis and bacillus typhosus has been determined. many substances have been found with especial restraining power for the tubercle bacillus under the conditions of the test. this capacity to restrain growth in the case of the tubercle bacillus apparently bears no simple relation to true disinfectant action. opinion as to whether the active substances exert a truly specific activity against the tubercle bacillus ... | 1917 | 19868100 |
| the bacillus tuberculosis: its morphological and pathological characteristics. | 1920 | 20891803 | |
| the complement fixation reaction as applied to leprosy. | by means of a method differing in important details from those of previous investigators it has been determined that the blood serum of cases of leprosy exhibits the ability to fix complement with a wide variety of antigens including to a greater or less extent those derived from any culture of the acid-fast group of bacteria available to us. this property of multiple fixation may sufficiently characterize the disease to be of diagnostic significance, although our experience is hardly sufficient ... | 1923 | 19868785 |
| direct cultivation of the mycobacterium tuberculosis. | 1925 | 18011589 | |
| allergic irritability : iii. the influence of chronic infections and of trypan blue on the formation of specific antibodies. | 1. the allergic irritability of the guinea pig (capacity of the animal to react to antigenic substances) is increased by infection with bacillus abortus and a streptococcus, by the dead tubercle bacillus, and by intensive treatment with trypan blue, respectively. the effect of these influences, while definite, is less pronounced than that previously found for infection with the tubercle bacillus. the production of anti-sheep hemolytic amboceptor was used as the test reaction in these cases. 2. t ... | 1926 | 19869120 |
| susceptibility of the gopher (citellus tridecemlineatus) to mycobacterium tuberculosis. | 1931 | 19969954 | |
| the pathological changes following experimental exposure of dogs to mycobacterium tuberculosis of avian origin. | 1931 | 19969955 | |
| the induced development of non-acid-fast forms of bacillus tuberculosis and other myco-bacteria. | six strains of mycobacteria,-three human strains, saranac h-37, t. s., and no. 90, a bovine strain, b-1, a smegma strain, no. 74, and a saranac strain of b. phlei,-have been made to grow as non-acid-fast organisms by the addition to the culture media of a filtered extract of the chromogenic h-37 strain of b. tuberculosis. the action of the extract produced acceleration of growth of the treated culture, followed by macroscopic and microscopic changes, and differentiation into non-acid-fast forms. ... | 1932 | 19870075 |
| phenomenon of local skin reactivity to bacillus tuberculosis : i. skin-preparatory and reacting potencies of tuberculin, o.t., and bacillus tuberculosis culture filtrates. | new toxic substances in certain tuberculin, o.t., and b. typhosus culture filtrates are described. these substances are capable of eliciting the hemorrhagic necrosis characteristic of the phenomenon of local skin reactivity provided heterologous bacterial filtrates of high potency are used either for the intradermal or the intravenous injection. the toxic substances apparently have no relationship to the tuberculin substances proper. the experiments with inactive preparations also demonstrate in ... | 1935 | 19870365 |
| the types of mycobacterium tuberculosis prevailing in montreal : (an interim report). | 1936 | 20320444 | |
| inhibitory action of colloidal sulphur in corper's agar on the growth of four strains of mycobacterium tuberculosis hominis. | 1936 | 18014482 | |
| effectiveness of hot hypochlorites of low alkalinity in destroying mycobacterium tuberculosis. | 1936 | 16559929 | |
| glycerol and carbohydrate utilization by mycobacterium tuberculosis. | 1936 | 16559976 | |
| the relation between the growth of mycobacterium tuberculosis and the yield of tuberculin on synthetic media. | 1937 | 16560014 | |
| infection of adult cattle with mycobacterium tuberculosis avium. | 1941 | 20475596 | |
| the history of six old cultures of mycobacterium tuberculosis. | 1941 | 20475608 | |
| the influence of sulfanilamide upon the yellow pigment formed by mycobacterium tuberculosis from p-aminobenzoic acid. | 1944 | 16560821 | |
| a yellow pigment formed from p-aminobenzoic acid by mycobacterium tuberculosis var. hominis. | 1944 | 16560840 | |
| inhibition of growth of mycobacterium tuberculosis by a mold. | 1944 | 17817564 | |
| [not available]. | 1945 | 20292247 | |
| [not available]. | 1945 | 20292248 | |
| [not available]. | 1945 | 20292252 | |
| [not available]. | 1945 | 21013553 | |
| [not available]. | 1945 | 20986318 | |
| tubercle bacilluria. | 1945 | 21005401 | |
| activity of helvolic acid against mycobacterium tuberculosis. | 1945 | 21006490 | |
| antibiotic substances active against m. tuberculosis. | 1945 | 21007941 | |
| [not available]. | 1945 | 21012665 | |
| inhibition of growth of mycobacterium tuberculosis by a mold product. | 1945 | 17740753 | |
| an antibiotic substance active against mycobacterium tuberculosis. | 1945 | 17799206 | |
| the tuberculostatic action of the sodium salts of certain synthetic alicyolic acids. | 1946 | 21013262 | |
| determination of pathogenicity of tubercle bacilli by their intermediate metabolism. | 1946 | 21008765 | |
| inhibition of growth of mycobacterium tuberculosis by a mold product; the effect on pathogenic human tubercle bacilli. | 1946 | 21012224 | |
| [not available]. | 1946 | 20989746 | |
| laboratory aids in the diagnosis and treatment of tuberculosis. | 1946 | 20991069 | |
| vaccination with the vole bacillus (wells); protective value of percutaneous and intracutaneous vaccination; observations on multiple puncture vaccination on man. | 1946 | 20995858 | |
| a study of the relationship of resistance, allergy, antibody and tissue reactivity in tuberculosis to the components of the tubercle bacillus. | 1946 | 21000309 | |
| the effect of para-amino-salicylic acid in vitro and in vivo on virulent human type tubercle bacilli. | 1946 | 21002634 | |
| detection of tubercle bacilli by the fluorescence technique. | 1946 | 21003293 | |
| cultural examination for mycobacterium tuberculosis; results in a public health laboratory over a four-year period. | 1946 | 21016352 | |
| effect of some fatty acids on the oxygen uptake of mycobact. tubercul.hum. in relation to their bactericidal action. | 1946 | 21017939 | |
| susceptibility of the golden hamster (cricetus auratus) to mycobacterium tuberculosis hominis and bovis. | 1946 | 21023168 | |
| the effects of (a) freeze-drying and (b) low temperature on the viability of mycobacterium tuberculosis. | 1946 | 21023169 | |
| a nucleoprotein from avian tubercle bacilli. | 1946 | 21026223 | |
| isolation of mycobacterium tuberculosis from gastric contents neutralized after varying periods. | 1946 | 21027326 | |
| the influence of streptomycin and promin on the proliferation of tubercle bacilli in the tissues of the albino rat. | 1946 | 20983213 | |
| immunization with the vole bacillus; the protective value of the vole bacillus (wells) as compared with bcg against tuberculous infection. | 1946 | 20984406 | |
| vole bacillus; susceptibility of south african wild rodents to the vole strain of acid-fast bacillus and to other acid-fast bacilli; preliminary report. | 1946 | 20984407 | |
| virulence of tubercle bacilli; in vitro testing by the use of diphtheria antitoxin. | 1946 | 20984413 | |
| [not available]. | 1946 | 20986215 | |
| a comparison of various egg media for the routine isolation of mycobacterium tuberculosis. | 1946 | 21065048 | |
| inhibition of mycobacterium tuberculosis by garlic extract. | 1946 | 21066575 | |
| [not available]. | 1946 | 20278826 | |
| synthesis of b-complex vitamins by tubercle bacilli when grown on synthetic media. | 1946 | 20286146 | |
| the relationship of acquired resistance, allergy, antibodies and tissue reactivities to the components of the tubercle bacillus. | 1946 | 20286147 | |
| the effect of water soluble lipids on the growth and biological properties of tubercle bacilli. | 1946 | 20274625 | |
| the relation between chemical structure of sulfones and their bacteriostatic activity. | 1946 | 20274636 | |
| a comparison of the effect of p-amino phenyl sulfone compounds in vitro and in vivo on tubercle bacilli. | 1946 | 20274637 | |
| the tubercle bacillus and fundamental chemotherapeutic and antibiotic action. | 1946 | 20275719 | |
| on the nature of two carboxylic acids of high molecular weight obtained from the waxes of acid-fast bacteria. | 1946 | 20276126 | |
| report of the committee on evaluation of laboratory procedures [american trudeau society]. | 1946 | 20279516 | |
| growth inhibition of tubercle bacilli by fusariun, sp. | 1946 | 20281110 | |
| the effect of penicillin on the tubercle bacillus. | 1946 | 20283086 | |
| the effect of penicillin on the growth of human type m. tuberculosis. | 1946 | 20283087 | |
| the use of mice in the examination of drugs for chemotherapeutic activity against mycobacterium tuberculosis. | 1946 | 20283100 | |
| evolution of mycobacterium tuberculosis. | 1946 | 20341443 | |
| [not available]. | 1946 | 20296700 | |
| [not available]. | 1946 | 20297325 | |
| [not available]. | 1946 | 20294007 | |
| [bacilli-status of tuberculosis in very young children]. | 1946 | 20290690 | |
| [not available]. | 1946 | 20246654 | |
| [not available]. | 1946 | 20249334 | |
| inhibition of growth of mycobacterium tuberculosis by a mold product--the effect on pathogenic human tubercle bacilli. | 1946 | 17784178 | |
| streptomycin sensitivity of tubercle bacilli; studies on recently isolated tubercle bacilli and the development of resistance to streptomycin in vivo. | 1947 | 20253121 | |
| streptomycin resistant strains of tubercle bacilli; production of streptomycin resistance in vitro. | 1947 | 20253122 |