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ectoparasite infestations and canine infection by rickettsiae and ehrlichiae in a semi-arid region of northeastern brazil.this study investigated the prevalence of rickettsia spp. and ehrlichia canis infection in dogs and their ectoparasites from rural and urban areas of two municipalities, petrolina and juazeiro, within a semiarid region (caatinga biome) of northeastern brazil, by immunofluorescence assay (ifa) and polymerase chain reaction (pcr). overall, 12.1% (61/504) and 23.0% (116/504) of canine plasma samples had antibodies reactive to rickettsia spp. and e. canis. e. canis dna was detected by pcr in 8.3% (4 ...026565771
tick-borne rickettsial pathogens in questing ticks, removed from humans and animals in mexico.tick-borne rickettsial diseases (tbrd) are commonly encountered in medical and veterinary clinical settings. the control of these diseases is difficult, requiring disruption of a complex transmission chain involving a vertebrate host and ticks. the geographical distribution of the diseases is related to distribution of the vector, which is an indicator of risk for the population. a total of 1107 were collected by tick drag from forests, ecotourism parks and hosts at 101 sites in 22 of the 32 sta ...026726019
ehrlichia canis infections in dogs on aruba (netherlands antilles). 195713428628
studies on ehrlichia canis (syn. rickettsia canis). 195913670021
effect of immunosuppressive therapy for renal transplantation in man on marrow and blood. 19684178180
impaired binding of mitochondrial adenosine triphosphatase in the cytoplasmic "petite" mutant of saccharomyces cerevisiae. 19684231098
[the influence of angiotensin on the glucose blood level in rabbits]. 19684302712
the calculated nitrogen requirements of a single cell of escherichia coli. 19684869285
the effect of actinomycin d on the synthesis of influenza virus-specific rna. 19694890919
the role of selection in the host-mediated assay for mutagenicity. 19694895527
[characteristics of high-molecular dna-like rna in animal cells]. 19694895566
biosynthesis and release of vasopressin and neurophysin. 19694902949
kiel bone in the treatment of pseudarthrosis. an experimental study. 19694913656
evidence for soluble immune complexes in the pathogenesis of the glomerulonephritis of quartan malaria. 19694178980
self photo-desensitization in man and baboon. 19694187369
quantitative bacteriology in the clinical testing of new antituberculosis drugs. 19694990183
ehrlichia canis--the causative agent of a haemorrhagic disease of dogs? 19695356929
tropical canine pancytopaenia and ehrlichia canis infection. 19705442103
the response of the sebaceous glands of hypophysectomized-castrated male rats to adrenocorticotrophic hormone and to testosterone. 19704319577
[the sulfametopyrazine-pyrimethamine combination in the treatment of 100 p. falciparum malarial attacks]. 19704928314
epizootiology of tropical canine pancytopenia.tropical canine pancytopenia (tcp) is a newly recognized infectious disease of dogs in diverse tropical and subtropical areas. the disease is characterized by hemorrhage, pancytopenia, severe emaciation and persistent infection. dogs with tcp are often presented with epistaxis, which is the most dramatic sign of the disease; however, a large number of affected dogs develop severe pancytopenia and die without manifesting clinical signs of hemorrhage. the disease has been reported most frequently ...197016512116
in vivo depression of hepatic succinoxidase by sulfhydryl compounds. 19714324834
two different complement fixing antigens found in the burkitt lymphoma cell cultures. brief report. 19714325972
cholinergic activity in rats following enriched stimulation and training: direction and duration of effects. 19714326332
[mechanism of the positive ionotropic action of theophylline on the mamalian heart. i. influence of extracellular ca, na and k concentrations and of reserpine]. 19714257640
a new strain of ehrlichia canis. 19715128792
studies on ehrlichia canis. 19715148310
diagnosis of tropical canine pancytopaenia (ehrlichia canis infection) by immunofluorescence. 19714104331
tropical canine pancytopenia: in vitro cultivation of the causative agent--ehrlichia canis. 19714107760
the chemistry of allergens. xxi. eight new antigens generated by successive pepsin hydrolyses of bovine -lactoglobulin. 19724114295
serological diagnosis of tropical canine pancytopenia by indirect immunofluorescence.an indirect fluorescent-antibody test for detection and titration of antibodies to ehrlichia canis, the causative agent of tropical canine pancytopenia, has been described. the organism propagated by an in vitro technique in canine blood monocytes served as an antigen in the test. the specificity of the test was revealed by absence of cross-reactivity between the antigen and sera from dogs infected with various common pathogens and specific sera against eight rickettsial species. the accuracy of ...19724118045
relation between carrier-state oxytetracycline administration and immunity in ehrlichia canis infections. 19725041029
the influence of chlorprothixene, methiothepine and reserpine on the resistance of the central nervous system of the rats against ischemia during ontogeny. 19725052812
recent investigations on the prosthetic group of beef plasma amine oxidase. 19725054201
ehrlichia canis and tropical canine pancytopaenia. 19725072572
role of herpesviruses in malignant lymphoma in rabbits. 19724351372
role of herpesviruses in malignant lymphoma in rabbits. 19724351372
isolation of duck haemoglobin messenger rna and its translation by rabbit reticulocyte cell free system. 19724501199
infected surface wound: an experimental model and a method for the quantitation of bacteria in infected tissues.methods for the quantitation of bacteria in infected tissues must be rigidly standardized to insure uniformity of results. in this communication we report on a laboratory animal model for the study of surface wound infection and the development of a standardized method for the quantitative estimation of bacteria in infected surface wound tissue by mechanical tissue homogenization and serial dilution. parallel comparative studies demonstrated that a moist-swab sampling procedure detected only 10% ...19724623279
the specificity of a bovine fibroblast cathepsin d. i. action on the s-sulfo derivatives of the insulin a and b chains and of porcine glucagon. 19724635824
structure of ehrlichia canis in blood monocytes of a dog. 19724641202
[healing of an intra-articular fracture of the rabbit under experimental conditions]. 19724652196
a comparative study of the pathogenicities of old and new world strains of ehrlichia canis. 19724671480
reactions of fluoride and carbonate ions during dissolution and mineralization of partially recalcified dentin. 19734703038
red and gray foxes--potential reservoir hosts for ehrlichia canis. 19734735125
ultrastructure of ehrlichia canis.the ultrastructure of ehrlichia canis was examined in both pulmonary mononuclear cells and in monocytes cultured from an infected dog. the cytoplasmic inclusions, or morulae, of e. canis consisted of a membrane-lined vacuole-containing elementary bodies which varied in size and number. the elementary bodies were bound by two trilamellar membranes. the organism shared morphological properties of both the genus rickettsia and genus chlamydia.19734735376
[radioimmunologic studies on serum progesterone in normal and induced menstrual cycle]. 19734736277
corticosteroids and the initiation of parturition in the human. 19734761219
ehrlichia canis infection. (tropical canine pancytopaenia or canine rickettsiosis). 19734787762
[sensitivity against various chemotherapeutic agents of staphylococcus strains isolated from human material of various origin]. 19734806388
[sensitivity against various chemotherapeutic agents of staphylococcus strains isolated from human material of various origin]. 19734806388
phagocytosis of salmonella typhimurium 395 mr10 by rabbit polymorphonuclear leucocytes: formation of phagolysosomes demonstrated by zonal separation. 19734588020
the isolation and survival characterization of radiation and chemical-mutagen sensitive mutants of pseudomonas aeruginosa. 19734356739
the isolation and survival characterization of radiation and chemical-mutagen sensitive mutants of pseudomonas aeruginosa. 19734356739
binding of spin-labeled local anesthetics to phosphatidylcholine and phosphatidylserine liposomes. 19744369807
closed circular dnas with tandem repeats of a sequence from polyoma virus. 19744369867
hypothalamic nuclei of rats after head irradiation and adrenocortical hormone treatment. 19744371631
relationship of ehrlichia canis-infected mononuclear cells to blood vessels of lungs.the lung tissue of six dogs with ehrlichiosis and two control dogs was examined with the electron microscope. mononuclear cells containing inclusions (morulae) of ehrlichia canis were adhered at one or more sites to the luminal surfaces of endothelial cells of arterioles or capillaries by way of interdigitations or areas of adherence, or an endothelial cell-bound mononuclear cell was chained to another parasitized or nonparasitized mononuclear cell in the lumen. the bifurcation of arterioles was ...19744372174
studies on amino acid utilization in relation to virulence of macrophomina phaseoli causing disease of jute (corchorus capsularis l.). 19744407383
latencies in a thermosensitive pathway. 19744435121
a serum factor in chronic hypocomplementemic hephritis distinct from immunoglobulins and activating the alternate pathway of complement.nephritic factor (c3nef) has been isolated from plasma of patients with hypocomplementemic chronic glomerulonephritis (hcg) by ion exchange and molecular sieve chromatography. this material was further treated with solidified anti-ig antiserum. the purified material failed to react with antiserum to human igg, igg3, fab, fc, and kappa and lambda chains, but retained full c3nef activity. the nonidentity of c3nef with igg was further demonstrated by ouchterlony analysis using anti-igg and anti-c3n ...19744207623
the role of genetics in human cancer. 19744210855
increased diamine oxidase activity in the intestinal lymph of rats on fat ingestion. 19744212082
[morphological phase-contrast cinematographic studies of bone marrow and blood cells in vitro. 8. monocyte system in man]. 19744589947
biological effects associated with the modification of intraphage dna with o-methylhydroxylamine. 19744610346
effect of na+ on ca-uptake of the synaptic plasma membrane. 19744549937
tropical canine pancytopenia: clinical, hematologic, and serologic response of dogs to ehrlichia canis infection, tetracycline therapy, and challenge inoculation. 19744140878
kinetics of antibody response to ehrlichia canis assayed by the indirect fluorescent antibody method.the kinetics of antibody production response to experimentally induced infection of dogs with ehrlichia canis was determined by ion-exchange and molecularsieve chromatography and by indirect fluorescent antibody (ifa) test. the first ifa antibody at 7 days after inoculation resided in immunoglobulin m (igm) and immunoglobulin a (iga) classes. at approximately 21 days after inoculation, the antibody was in igm, iga, and immunoglobulin g (igg) classes. thereafter, antibody concentrations continued ...197549162
sex specific oestrogen binding in the middle hypothalamus of rats. 1975179802
malignant transformation-linked imbalance: decreased xanthine oxidase activity in hepatomas.xanthine oxidase was decreased 2- to 10-fold in all examined rat hepatomas irrespective of the malignancy; growth rate and degrees of histological differentiation of the neoplasms. the affinity to substrate (km=6-8 mum) and the ph optimum (8.0) of the liver and hepatoma enzymes were the same. the reprogramming of gene expression, as manifested in the decreased activity of this key purine metabolizing enzyme, appears to be specific to neoplastic transformation. since glutamine prpp amidotransfera ...1975179860
effect of morphine on intracranial self-stimulation behavior following brain amine depletion. 1975124807
ultrastructural aspects of cardiac lymphatic capillaries in experimental cardiac hypertrophy. 1975124810
flaujeac trait. deficiency of human plasma kininogen.flaujeac trait plasma resembled hageman trait or fletcher trait, in that the intrinsic coagulation pathway, plasma fibinolytic pathway, kinin-forming system, permeability factor of dilution (pf/dil) phenomenon were abnormal. the defect in each assay was reconstituted by afactor separable from hageman factor or fletcher factor. this substance was an alpha-globulin with an approximate mol wt of 170,000. flaujeac plasma did not release a kinin upon incubation with kallikrein and was deficient in to ...1975127805
the nature of the protein moieties of cartilage proteoglycans of pig and ox.proteoglycans extracted with 4m-guanidinium chloride from pig laryngeal cartilage and bovine nasal septum were purified by density-gradient centrifugation in cscl under 'associative' followed by 'dissociative' conditions [hascall & sajdera (1969) j. biol. chem. 244, 2384-2396]. proteoglycans were then digested exhaustively with testicular hyaluronidase, which removed about 80% of the chondroitin sulphate. the hyaluronidase was purified until no proteolytic activity was detectable under the condi ...1975128355
pre- and postnatal enzyme capacity for drug metabolite production.most lipid-soluble foreign compounds including drugs, insecticides and many environmental pollutants are metabolized in animals by cytochrome p-450 enzymes in the endoplasmic reticulum of liver. these enzymes are virtually absent in fetuses of laboratory animals, but their activities increase to adult levels within 3-8 weeks after birth. in human fetuses, the enzymes appear during the first half of pregnancy, and their activities during gestation reach about one third of those found in adults. t ...19751090453
isolation in illinois of a foreign strain of ehrlichia canis, the causative agent of canine ehrlichiosis (tropical canine pancytopenia).ehrlichiosis (tropical canine pancytopenia) was diagnosed in illinois in a 4 1/2-year-old mixed breed dog that had spent the previous 2 years in india. the dog had periodic epistaxis, anemia, leukopenia, hypoalbuminemia, and hypergammaglobulinemia. a titer of 1:160 for ehrlichia canis was detected by the indirect fluorescent antibody test (ifat). subinoculation of blood into a clinically normal dgo resulted in typical signs of canine ehrlichiosis, and e canis was identified in circulating mononu ...19751112743
experimentally induced infection of dogs, cats, and nonhuman primates with ehrlichia equi, etiologic agent of equine ehrlichiosis.dogs (german shepherd dogs and beagles), cates, rhesus macaques (macaca mulatta), and baboons (papio anubis) were inoculated with whrlichia equi, the etiologic agent of equine ehrlichiosis. within 3 to 7 days after inoculation, morulae were observed in the eosinophils of cats, neurtrophils of macaques and baboons, and in both neutrophils and eosinophils of dogs. the severe disease produced in horses by this agent was not a feature of e equi infection in dogs, cats, macaques, and baboons. however ...19751115421
platelet kinetics in canine ehrlichiosis: evidence for increased platelet destruction as the cause of thrombocytopenia.a significant (p < 0.025) increase in the mean platelet diameter occurred in five ehrlichia canis-infected dogs when platelet numbers decreased to 100,000/mul or less. maximal incorporation of [(75)se]selenomethionine into platelets of six uninfected dogs was 0.080 +/- 0.019% (mean +/- standard error) and occurred 5 to 6 days after dosage, whereas maximal incorporation was 0.036 +/- 0.004% within 2 to 3 days after dosage in seven chronically infected dogs that had thrombocytopenia. analysis of t ...19751140846
transmission of ehrlichia canis to dogs by ticks (rhipicephalus sanguineus).two strains of rhipicephalus sanguineus acquired ehrlichia canis by feeding as either larvae or nymphs on acutely infected dogs and, in subsequent instars, transmitted the agent to normal dogs. three strains of r sanguineus transmitted e canis as adults after their larval and nymphal stages fed on infected dogs. more than 400 adult female ticks were fed on infected dogs as larvae or nymphs or both, but none transmitted e canis transovarially.19751147359
ehrlichia canis infection in a dog in virginia. 19751150498
inhibitory effects of mersalyl and of antibodies directed against smooth-muscle myosin on a calcium adenosine triphosphatase of the plasma membrane from mouse liver cells. 1976130830
development of ehrlichia canis, causative agent of canine ehrlichiosis, in the tick rhipicephalus sanguineus and its differentiation from a symbiotic rickettsia.certain aspects of the development of ehrlichia canis, causative agent of canine ehrlichiosis (tropical canine pancytopenia) in rhipicephalus sanguineus ticks were studied. it was found that partial feeding of nymphs infected as larvae with e canis was a desirable, if not necessary, preliminary treatment for successful infection of dogs with ground-up ticks. it remains unclear whether feeding increased the number or altered the virulence of ehrlichiae within tick tissues. ehrlichia canis organis ...1976944000
identification of ehrlichia canis in east africa.ehrlichia canis, the causative agent of canine ehrlichiosis or tropical canine pancytopaenia (tcp) has been identified in kenya. transmission studies to two dogs resulted in signs of ehrlichiosis including marked thrombocytopaenia, pyrexia, reduction in the packed cell volume and the presence of e canis in peripheral blood mononuclear cells.1976997191
autologous lymphocyte-mediated cytotoxicity against monocytes in canine ehrlichiosis.the 51cr-release technique for detecting cytotoxicity had been adapted to immunologic studies of canine ehrlichiosis. lymphocytes from dogs infected with ehrlichia canis, cause of canine ehrlichiosis, were shown to be cytotoxic for autologous monocytes. the effect was dependent on the concentraton of lymphocytes, being optimal at 100:1 lymphocyte:monocyte ratio. neither immune serum and complement, nor anti-canine globulin had any observable effect on cytotoxicity. the monocytotoxicity bore a te ...1977931138
canine peritoneal macrophages: cultivation and infection with ehrlichia canis.canine peritoneal macrophages were obtained by repeated peritoneal lavage of dogs at 14 day intervals. intraperitoneal administration of sterile mineral oil increased the leukocyte yield approximately 20-fold and the macrophage recovery approximately 35-fold. cell recovery was maximum 7 to 21 days after administration of oil and declined slightly by 35 days. restimulation with a 2nd injection of oil promptly revitalized cell recovery. peritoneal macrophage cultures were well established by 6 day ...1977931165
acute canine ehrlichiosis: platelet survival and factor 3 assay.ten dogs experimentally inoculated with ehrlichia canis were thrombocytopenic 14 days after inoculation. circulating platelet concentrations had declined rapidly by postinoculation day 10, but remained at or slightly below the 14-day concentration during the remainder of the 42-day experimental period. the percentage of circulating megathrombocytes also increased to 8.7 times preinoculation concentrations indicating the existence of accelerated thrombocytopoiesis. the release of platelet factor ...1977931166
the brown dog tick rhipicephalus sanguineus and the dog as experimental hosts of ehrlichia canis.adult rhipicephalus sanguineus ticks efficiently transmitted ehrlichia canis to susceptible dogs for 155 days after detachment as engorged nymphs from a dog in the acute phase of ehrlichiosis. adult ticks that had similarly engorged on a dog in the chronic phase of ehrlichiosis failed to transmit e canis to susceptible dogs. infected but unfed adult ticks may be of greater importance than the chronically infected carrier dog as a natural reservoir of e canis.1977596693
surface ultrastructural response of the human uterine lining epithelium to hormonal environment. a scanning electron microscopic study. 1977269610
therapy for infections due to anaerobic bacteria: an overview.several classes of antimicrobial agents (e.g., penicillins, cephalosporins, tetracyclines, chloramphenicol, and clindamycin) are useful in treatment of infections due to anaerobic bacteria. however, certain anaerobic bacteria have shown a striking resistance to antimicrobial agents. in vitro susceptibility tests are useful for selection of optimal therapy. the choice of agent depends, to some extent, on the organisms responsible for the infection. bacteroides fragilis is the most commonly encoun ...1977321708
[the ovary and the immunity system]. 1977340059
structural studies and physical maps for the herpes simplex virus genome. 1977193820
[study of cytoplasmic rna in tissues of the rat, regenerating liver and in liver of rats with hepatoma pc-1].cytoplasmic rna of the rat regenerating liver and liver of rats with hepatoma pc-1 is separated into five fractions on the column of kieselgur with methylated albumin (mak). studies in the nucleotide composition showed that certain fractions of cytoplasm rna are ribosomal and messenger rna. the highest amount of radioactive precursor is incorporated into messenger rna of the rat regenerating liver and liver of the rats with hepatoma pc-1 which is eluated from the column by 0.2% solution of sodiu ...1977201068
the presence of disulfide-linked gp70-p15(e) complexes in akr murine leukemia virus. 1977201090
giant group a marker chromosome in three human lymphoblastoid cell strains from nasopharyngeal carcinoma. 197895929
hematological data of the laboratory-maintained bonnet (macaca radiata) and the langur (presbytis entellus entellus) monkeys. 197895998
ultrastructural localization of calcium around the membrane of the surface connected system in the human platelet.the localization of calcium in the membrane system of human platelets was determined by ultrahistochemical methods equipped with an electron probe x-ray microanalyzer. after potassium oxalate-glutaraldehyde treatment large amounts of electron opaque precipitates were observed around the membrane of the surface connected system. electron probe x-ray microanalysis clearly defined that the precipitates were composed of calcium oxalate. the localization of calcium on the membrane of the surface conn ...197896043
[adaptation of lipase and phospholipase a activities in pancreas and pancreatic juice in rats with diets rich in triglycerides and phospholipids].lipid rich diets containing about 20% of triglycerides or phospholipids given to rats during 2 months were observed to increase lipase and phospholipase a2 activities in pancrease and pancreatic juice. the phospholipase and lipase activities are higher, respectively, on the phospholipid and triglyceride diet. lower effects are observed after a 7-day administration of diet containing 40% of total lipid.197896963
[the effects of testosterone and estradiol on the activity of lysosomal enzymes in rat liver and kidneys].in in vitro tests with lysosomes isolated from the liver and kidneys of castrated rats of both sexes the action of testosterone and beta-estradiol in concentrations of 3.76.10(-4)m on the activity of beta-glucosidase, beta-galactosidase and acid phosphatase was investigated. testosterone is shown to reduce the total and free activity of the membrane-bound enzymes and to increase the release from the matrix lysosomes. estradiol proved less active than is testosteron. the renal lysosomes in vitro ...197897095
induction of arylhydrocarbon hydroxylase and udp glucuronosyl transferase by pcb in hepatic cell cultures.the purpose of the investigation was to derive a hepatic cell line to be used in induction studies of drug metabolizing enzymes. two pure cell lines were isolated from primary liver cell cultures, one with an epithelial-like appearance, the other with a fibroblast-like appearance. the specific activities of arylhydrocarbon hydroxylase (ahh) and udp glucuronosyl transferase (udpgt) were greater in hepatocyte cultures than in primary cultures or in fibroblast cultures. pcb enhanced the activity of ...197898133
[immuno-electro-diffusion on cellulose acetate membrane for serological testing in human malaria (author's transl)].an immuno-electro-diffusion assay for human malaria, using cellulose acetate gel, is described. more than 3500 sera have been tested by this method, which proved very useful for epidemiology since 400 sera a day can be tested by one person, with simple equipment. its sensitivity compared well to the ifa test, although the antibodies revealed are quite different. a constnat precipitin line appeared, against 56 degrees c labile antigens, in sera of subjects infected by p. falciparum, and up to 8 o ...197898748
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