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in vitro antiherpetic and antirotaviral activities of a sulfate prepared from mimosa scabrella galactomannan.a chemically sulfated galactomannan (brs) from seeds of mimosa scabrella had in vitro antiviral activity against herpes simplex virus 1 (hsv-1), but not against simian rotavirus a/sa11 (sirv-a/sa11). it was examined by (13)c nmr spectroscopy, which showed the sulfate groups to be mainly at c-6 of galactose residues. brs had a selective inhibition against hsv-1 during its attachment step, having an ic(50) lower than 2.5microg/ml, determined by plaque reduction, and a selectivity index of greater ...200919751759
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