Publications

TitleAbstractYear
Filter
PMID(sorted descending)
Filter
biogenic amine formation and microbiological quality of anchovy (engraulis encrasicolus) treated with lavender and lemon balm ethanol extracts.biogenic amine formation and bacterial growth of vacuum-packed european anchovy treated with 1% lemon balm (lb) or lavender (ld) ethanol extracts was investigated. the treated samples were stored at 2 ± 1 °c for 11 d and analyzed for biogenic amines, total viable count, fecal coliform count, and lactic acid bacterial count. the analyses were done on 0, 4, 7, 9, and 11 d of storage. both lb and ld extracts proved effective in reducing most biogenic amines, with histamine reduced by 3-fold compare ...201728369977
melissopalynological characterization of north algerian honeys.a pollen analysis of algerian honey was conducted on a total of 10 honey samples. the samples were prepared using the methodology described by louveaux et al., that was then further adapted by ohe et al. the samples were subsequently observed using light microscopy. a total of 36 pollen taxa were discovered and could be identified in the analyzed honey samples. seventy percent of the studied samples belonged to the group ofmonofloral honeys represented by eucalyptus globulus, thymus vulgaris, ci ...201328239099
chemical composition, antioxidant and antimicrobial activity of essential oils from organic fennel, parsley, and lavender from spain.the aim of this work was to (i) determine the chemical composition of the essential oils of three spices widely cultivated in spain from organic growth: foeniculum vulgare, petroselium crispum, and lavandula officinalis; (ii) determine the total phenolic content; (iii) determine the antioxidant activity of the essentials oils by means of three different antioxidant tests and (iv) determine the effectiveness of these essentials oils on the inhibition of listeria innocua cect 910 and pseudomonas f ...201628231113
three new benzolactones from lavandula angustifolia and their bioactivities.three new benzolactones (1-3), together with four known ones (4-7), were isolated from the whole herb of lavandula angustifolia. their structures were established on the basis of detailed spectroscopic analysis (1d- and 2d-nmr, hresims, uv, and ir) and comparison with data reported in the literature. new compounds were evaluated for their anti-tobacco mosaic virus (tmv) activities and cytotoxic activities. the results revealed that compounds 1-3 showed obvious anti-tmv activities with inhibition ...201627967214
coriandrum sativum and lavandula angustifolia essential oils: chemical composition and activity on central nervous system.the aims of this study are to determine the chemical composition of lavandula angustifolia mill. and coriandrum sativum l. essential oils, to evaluate their cytotoxic effects in sh-sy5y human neuroblastoma cells, to investigate whether an alteration of adenylate cyclase 1 (adcy1) and of extracellular signal-regulated kinase (erk) expression can take part in the molecular mechanisms of the essential oils, and to study their possible neuronal electrophysiological effects. the essential oils were o ...201627916876
the in vitro antimicrobial effects of lavandula angustifolia essential oil in combination with conventional antimicrobial agents.the paper focuses on the in vitro antimicrobial activity of lavandula angustifolia mill. (lavender) essential oil in combination with four commercial antimicrobial agents. stock solutions of chloramphenicol, ciprofloxacin, nystatin, and fusidic acid were tested in combination with l. angustifolia essential oil. the antimicrobial activities of the combinations were investigated against the gram-positive bacterial strain staphylococcus aureus (atcc 6538) and gram-negative pseudomonas aeruginosa (a ...201627891157
in vitro activity of ten essential oils against sarcoptes scabiei.the development of alternative approaches in ectoparasite management is currently required. essential oils have been demonstrated to exhibit fumigant and topical toxicity to a number of arthropods. the aim of the present study was to assess the potential efficacy of ten essential oils against sarcoptes scabiei.201627876081
pseudomonas aeruginosa mastitis in two goats associated with an essential oil-based teat dip.pseudomonas aeruginosa is an opportunistic pathogen that has been associated with mastitis in dairy animals, including goats. often, the environmental sources of the bacteria are water-related (such as hoses and muddy pastures). mastitis attributable to p. aeruginosa was identified in 2 goats in a small herd. efforts were made to identify environmental sources of the pathogen. multiple samples from the goats' environment were cultured, including water from the trough, bedding, the hose used to w ...201627698173
representation of perceptual color space in macaque posterior inferior temporal cortex (the v4 complex).the lateral geniculate nucleus is thought to represent color using two populations of cone-opponent neurons [l vs m; s vs (l + m)], which establish the cardinal directions in color space (reddish vs cyan; lavender vs lime). how is this representation transformed to bring about color perception? prior work implicates populations of glob cells in posterior inferior temporal cortex (pit; the v4 complex), but the correspondence between the neural representation of color in pit/v4 complex and the org ...201727595132
liquid and vapour-phase antifungal activities of essential oils against candida albicans and non-albicans candida.the management of candida infections faces many problems, such as a limited number of antifungal drugs, toxicity, resistance of candida to commonly antifungal drugs, relapse of candida infections, and the high cost of antifungal drugs. though azole antifungal agents and derivatives continue to dominate as drugs of choice against candida infections, there are many available data referring to the anticandidal activity of essential oils. since we have previous observed a good antimicrobial activity ...201627576581
sensitivity of candida albicans to essential oils: are they an alternative to antifungal agents?candida albicans is an important opportunistic pathogen, responsible for the majority of yeast infections in humans. essential oils, extracted from aromatic plants, are well-known antimicrobial agents, characterized by a broad spectrum of activities, including antifungal properties. the aim of this work was to assess the sensitivity of 30 different vaginal isolated strains of c. albicans to 12 essential oils, compared to the three main used drugs (clotrimazole, fluconazole and itraconazole).201627568869
borneol dehydrogenase from pseudomonas sp. strain tcu-hl1 catalyzes the oxidation of (+)-borneol and its isomers to camphor.most plant-produced monoterpenes can be degraded by soil microorganisms. borneol is a plant terpene that is widely used in traditional chinese medicine. neither microbial borneol dehydrogenase (bdh) nor a microbial borneol degradation pathway has been reported previously. one borneol-degrading strain, pseudomonas sp. strain tcu-hl1, was isolated by our group. its genome was sequenced and annotated. the genome of tcu-hl1 consists of a 6.2-mbp circular chromosome and one circular plasmid, pthl1 (1 ...201627542933
disruption of host-seeking behaviour by the salmon louse, lepeophtheirus salmonis, using botanically derived repellents.the potential for developing botanically derived natural products as novel feed-through repellents for disrupting settlement of the salmon louse, lepeophtheirus salmonis (caligidae) upon farmed atlantic salmon, salmo salar, was investigated using an established laboratory vertical y-tube behavioural bioassay for assessing copepodid behaviour. responses to artificial sea water conditioned with the odour of salmon, or to the known salmon-derived kairomone component, α-isophorone, in admixture with ...201727496636
antifungal screening of lavender essential oils and essential oil constituents on three post-harvest fungal pathogens.a growing body of literature indicates that many synthetic pesticides have adverse effects on human, animal, and environmental health. as a result, plant-derived natural products are quickly gaining momentum as safer and less ecologically damaging alternatives due to their low toxicity, high biodegradability, and good specificity. essential oils of lavandula angustifolia, lavandula x intermedia cv grosso, and lavandida x intermedia cv provence as well as various mono- and sesquiterpene essential ...201627396210
the in vitro effect of selected essential oils on the growth and mycotoxin production of aspergillus species.the aim of the present study was to assess the antifungal and anti-toxinogenic activity of 15 essential oils (eos) against three fungi of the genus aspergillus (a. parasiticus kmi-227-lr, a. parasiticus kmi-220-lr and a. flavus kmi-202-lr). the minimum inhibitory doses (mids) of the tested essential oils and their antifungal activity were determined using the micro-atmosphere method. the original commercial essential oil samples of jasminum officinale l., thymus vulgaris l., syzygium aromaticum ...201627322876
high antiviral effects of hibiscus tea extract on the h5 subtypes of low and highly pathogenic avian influenza viruses.viral neuraminidase inhibitors are widely used as synthetic anti-influenza drugs for the prevention and treatment of influenza. however, drug-resistant influenza a virus variants, including h5n1 highly pathogenic avian influenza viruses (hpaivs), have been reported. therefore, the discovery of novel and effective antiviral agents is warranted. we screened the antiviral effects of 11 herbal tea extracts (hibiscus, black tea, tencha, rosehip tea, burdock tea, green tea, jasmine tea, ginger tea, la ...201627193820
odors bias time perception in visual and auditory modalities.previous studies have shown that emotional states alter our perception of time. however, attention, which is modulated by a number of factors, such as emotional events, also influences time perception. to exclude potential attentional effects associated with emotional events, various types of odors (inducing different levels of emotional arousal) were used to explore whether olfactory events modulated time perception differently in visual and auditory modalities. participants were shown either a ...201627148143
quantitative analysis of bioactive compounds from aromatic plants by means of dynamic headspace extraction and multiple headspace extraction-gas chromatography-mass spectrometry.seven monoterpenes in 4 aromatic plants (sage, cardamom, lavender, and rosemary) were quantified in liquid extracts and directly in solid samples by means of dynamic headspace-gas chromatography-mass spectrometry (dhs-gc-ms) and multiple headspace extraction-gas chromatography-mass spectrometry (mhse), respectively. the monoterpenes were 1st extracted by means of supercritical fluid extraction (sfe) and analyzed by an optimized dhs-gc-ms. the optimization of the dynamic extraction step and the d ...201626925555
a representative survey of knowledge, use, perceived benefits, barriers, and risks of select herbal drugs among female students in gorgan city (northeast iran).we conducted a representative survey among young women to determine knowledge, use, and perceptions on barriers, benefits, and risks related to selected herbal drugs (crocus sativus, borago officinalis, citrus aurantium, thymus vulgaris, matricaria chamomilla, lavandula angustifolia, valeriana officinalis, hypericum perforatum, and panax ginseng) in gorgan by using an internally validated questionnaire. there were 344 participants (mean age 16.3 years; 16.2% in science course). saffron had most ...201626888451
the use of aromasticks to help with sleep problems: a patient experience survey.to document the use of aromasticks to facilitate sleep in a cancer centre in the uk. sleep disturbance is a common problem amongst patients diagnosed with cancer. essential oils may be inhaled by means of an aromastick (a personal inhaler device containing essential oils) as a means of improving sleep. a prospective audit of aromasticks given to help facilitate sleep. sixty-five aromasticks were given out over a 13 week period. 94% of patients reported that they did use their aromastick to help ...201626850806
anti-inflammatory potential of ursolic acid in mycobacterium tuberculosis-sensitized and concanavalin a-stimulated cells.ursolic acid (3-β-3-hydroxy-urs-12-ene-28-oic-acid; ua) is a triterpenoid carboxylic acid with various pharmaceutical properties. it is commonly found in apples, basil, berries, rosemary, peppermint, lavender, oregano, thyme, hawthorn and prunes. in the present study, the activities of ua against the mycobacterium tuberculosis h37rv‑induced release of a panel of inflammatory cytokines, including tumor necrosis factor-α (tnf-α), interleukin (il)-1β and il-6 from raw 264.7 murine macrophages, a549 ...201626847129
hypnotic effect of coriandrum sativum, ziziphus jujuba, lavandula angustifolia and melissa officinalis extracts in mice.the aim of the present study was to evaluate hypnotic effect of coriandrum sativum, ziziphus jujuba, lavandula angustifolia and melissa officinalis hydroalcoholic extracts in mice to select the most effective ones for a combination formula. three doses of the extracts (250, 500 and 1000 mg/kg of c. sativum and z. jujuba and 200, 400 and 800 mg/kg of l. angustifolia and m. officinalis) were orally administered to male swiss mice (20-25 g) and one hour later pentobarbital (50 mg/kg, i.p.) was inje ...201726779267
essential oils to control ichthyophthiriasis in pacu, piaractus mesopotamicus (holmberg): special emphasis on treatment with melaleuca alternifolia.in vitro effect of the melaleuca alternifolia, lavandula angustifolia and mentha piperita essential oils (eos) against ichthyophthirius multifiliis and in vivo effect of m. alternifolia for treating ichthyophthiriasis in one of the most important south american fish, piaractus mesopotamicus (holmberg), were evaluated. the in vitro test consisted of three eos, each at concentrations of 57 μl l(-1) , 114 μl l (-1) , 227 μl l(-1) and 455 μl l (-1) , which were assessed once an hour for 4 h in micro ...201626776242
lavandula angustifolia mill. essential oil exerts antibacterial and anti-inflammatory effect in macrophage mediated immune response to staphylococcus aureus.different studies described the antibacterial properties of lavandula angustifolia (mill.) essential oil and its anti-inflammatory effects. besides, no data exist on its ability to activate human macrophages during the innate response against staphylococcus aureus. the discovery of promising regulators of macrophage-mediated inflammatory response, without side effects, could be useful for the prevention of, or as therapeutic remedy for, various inflammation-mediated diseases. this study investig ...201626730790
herbal medicine for low back pain: a cochrane review.systematic review of randomized controlled trials (rcts).201626630428
metabolic engineering of saccharomyces cerevisiae for linalool production.to engineer the yeast saccharomyces cerevisiae for the heterologous production of linalool.201626614300
linalool affects the antimicrobial efficacy of essential oils.the high concentrations of essential oils are generally required to receive microbial purity of the products (cosmetics, medicine). on the other hand, their application due to the high concentration of essential oils may be limited by changes in organoleptic and textural quality of the products, as well as they cause irritation and allergies in users. addition of linalool to essential oil may significantly enhance its antimicrobial effectiveness and reduce their concentrations in products, takin ...201626553262
antifungal effect of lavender essential oil (lavandula angustifolia) and clotrimazole on candida albicans: an in vitro study.background. the treatment of candidiasis infections is an important problem in the health care system. this study aimed to investigate the in vitro effect of lavender essential oil and clotrimazole on isolated c. albicans from vaginal candidiasis. materials and methods. in this clinical trial, c. albicans isolated from the vaginal discharge samples was obtained. results. the pairwise comparison showed that lavender and clotrimazole had a significant difference; this difference in the lavender gr ...201526550521
[differentiation of human umbilical cord mesenchymal stem cells into hepatocytes induced by rat fibrotic liver tissue extracts].to investigate the differentiation potential of human umbilical cord mesenchymal stem cells (hucmscs) into hepatocytes induced by rat fibrotic liver tissue extracts.201526540984
a systematic review of the anxiolytic-like effects of essential oils in animal models.the clinical efficacy of standardized essential oils (such as lavender officinalis), in treating anxiety disorders strongly suggests that these natural products are an important candidate source for new anxiolytic drugs. a systematic review of essential oils, their bioactive constituents, and anxiolytic-like activity is conducted. the essential oil with the best profile is lavendula angustifolia, which has already been tested in controlled clinical trials with positive results. citrus aurantium ...201526473822
"singing in the tube"--audiovisual assay of plant oil repellent activity against mosquitoes (culex pipiens).plant essential oils have been suggested as a promising alternative to the established mosquito repellent deet (n,n-diethyl-meta-toluamide). searching for an assay with generally available equipment, we designed a new audiovisual assay of repellent activity against mosquitoes "singing in the tube," testing single mosquitoes in drosophila cultivation tubes. statistics with regression analysis should compensate for limitations of simple hardware. the assay was established with female culex pipiens ...201626412058
toxicity of lavandula angustifolia oil constituents and spray formulations to insecticide-susceptible and pyrethroid-resistant plutella xylostella and its endoparasitoid cotesia glomerata.plutella xylostella is one of the most serious insect pests of cruciferous crops. this study was conducted to determine the toxicity of 21 constituents from lavandula angustifolia essential oil (la-eo) and another 16 previously known la-eo constituents and the toxicity of six experimental spray formulations containing the oil (1-6 g l(-1) sprays) to susceptible ks-px and pyrethroid-resistant jj-px p. xylostella larvae, as well as to its endoparasitoid cotesia glomerata adults.201626350499
a new species of dysmicoccus damaging lavender in french provence (hemiptera, sternorrhyncha, pseudococcidae).une nouvelle espèce de dysmicoccus nuisible à la lavande en provence (france) (hemiptera, sternorrhyncha, pseudococcidae). dysmicoccus lavandulae germain, matile-ferrero & williams n. sp. est décrite et illustrée. ses séquences adn sont présentées. l'espèce vit sur lavandula x intermedia cultivée pour la production d'essence de lavande en provence. la liste des espèces de pseudococcines vivant sur les lavandes spontanées en france est dressée. le statut des 2 genres voisins trionymus berg et dys ...201526249973
plant scents modify innate colour preference in foraging swallowtail butterflies.flower-visiting insects exhibit innate preferences for particular colours. a previous study demonstrated that naive papilio xuthus females prefer yellow and red, whereas males are more attracted to blue. here, we demonstrate that the innate colour preference can be modified by olfactory stimuli in a sexually dimorphic manner. naive p. xuthus were presented with four coloured discs: blue, green, yellow and red. the innate colour preference (i.e. the colour first landed on) of the majority of indi ...201526179802
[massage with aromatherapy: effectiveness on anxiety of users with personality disorders in psychiatric hospitalization].to investigate the effectiveness of aromatherapy massage using the essential oils (0.5%) of lavandula angustifolia and pelargonium graveolens for anxiety reduction in patients with personality disorders during psychiatric hospitalization.201526107706
phytopharmaceutical treatment of anxiety, depression, and dementia in the elderly: evidence from randomized, controlled clinical trials.based on subgroup analyses of randomized, controlled clinical trials, we review the efficacy of three phytopharmaceutical drugs, respectively of the corresponding active substances silexan® (ws® 1265, lavender oil) in anxiety disorders, ws® 5570 (hypericum extract) in major depression, and egb 761® (ginkgo biloba extract) in alzheimer, vascular, or mixed type dementia, in elderly patients aged ≥ 60 years. four trials were eligible in each indication. meta-analyses and analyses based on pooled ra ...201526092515
antimicrobial impacts of essential oils on food borne-pathogens.the antimicrobial activity of twelve essential oil (pine oil, eucalyptus, thyme, sage tea, lavender, orange, laurel, lemon, myrtle, lemon, rosemary and juniper) was tested by a disc diffusion method against food borne pathogens (escherichia coli, salmonella paratyphi a, klebsiella pneumoniae, yersinia enterocolitica, pseudomonas aeruginosa, aeromonas hydrophila, campylobacter jejuni, enterococcus faecalis, staphylococcus aureus). the major components in essential oils were monoterpenes hydrocarb ...201526072990
plant essential oils synergize and antagonize toxicity of different conventional insecticides against myzus persicae (hemiptera: aphididae).plant-derived products can play an important role in pest management programs. essential oils from lavandula angustifolia (lavender) and thymus vulgaris (thyme) and their main constituents, linalool and thymol, respectively, were evaluated for insecticidal activity and synergistic action in combination with insecticides against green peach aphid, myzus persicae (sulzer) (hemiptera: aphididae). the essential oils and their main constituents exerted similar insecticidal activity when aphids were e ...201526010088
the effect of ethanol on reversal learning in honey bees (apis mellifera anatolica): response inhibition in a social insect model.we investigated the effects of ethanol on reversal learning in honey bees (apis mellifera anatolica). the rationale behind the present experiment was to determine the species generality of the effect of ethanol on response inhibition. subjects were originally trained to associate either a cinnamon or lavender odor with a sucrose feeding before a reversal of the conditioned stimuli. we administered 15 μl of ethanol at varying doses (0%, 2.5%, 5%, 10%, or 20%) according to group assignment. ethano ...201525837483
antimicrobial activity of essential oils and carvacrol, and synergy of carvacrol and erythromycin, against clinical, erythromycin-resistant group a streptococci.in the present study, we have evaluated the in vitro antibacterial activity of essential oils from origanum vulgare, thymus vulgaris, lavandula angustifolia, mentha piperita, and melaleuca alternifolia against 32 erythromycin-resistant [mininum inhibitory concentration (mic) ≥1 μg/ml; inducible, constitutive, and efflux-mediated resistance phenotype; erm(tr), erm(b), and mef(a) genes] and cell-invasive group a streptococci (gas) isolated from children with pharyngotonsillitis in italy. over the pa ...201525784902
antifungal activity of essential oils against selected terverticillate penicillia.the aim of this study was to screen 15 essential oils of selected plant species, viz. lavandula angustifolia, carum carvi, pinus mungo var. pulmilio, mentha piperita, chamomilla recutita l., pinus sylvestris, satureia hortensis l., origanum vulgare l., pimpinella anisum, rosmarinus officinalis l., salvia officinalis l., abietis albia etheroleum, chamomilla recutita l. rausch, thymus vulgaris l., origanum vulgare l. for antifungal activity against five penicillium species: penicillium brevicompac ...201525780826
development and validation of an high-performance liquid chromatography-diode array detector method for the simultaneous determination of six phenolic compounds in abnormal savda munziq decoction.given the high-effectiveness and low-toxicity of abnormal savda munziq (asmq), its herbal formulation has long been used in traditional uyghur medicine to treat complex diseases, such as cancer, diabetes, and cardiovascular diseases.201725709227
contact dermatitis as an adverse reaction to some topically used european herbal medicinal products - part 2: echinacea purpurea-lavandula angustifolia.this review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the european medicines agency has completed an evaluation up to the end of november 2013 and for which a community herbal monograph has been produced. part 2: echinacea purpurea moench-lavandula angustifolia mill.201525600644
herbal medicine for low-back pain.low-back pain (lbp) is a common condition and imposes a substantial economic burden upon people living in industrialized societies. a large proportion of people with chronic lbp use complementary and alternative medicine (cam), visit cam practitioners, or both. several herbal medicines have been purported for use in treating people with lbp. this is an update of a cochrane review first published in 2006.201425536022
the biological activities of cinnamon, geranium and lavender essential oils.acinetobacter sp. represent an important cause of nosocomial infections. their resistance to some antibiotics, their ability to survive on inanimate surfaces in the hospital environment and their ability to produce biofilms contributes to their virulence. the aim of the study was to determine the antibacterial properties of cinnamon, lavender and geranium essential oils against bacteria of the genus acinetobacter isolated from several clinical materials and from the hospital environment. a compr ...201425514231
[effect of cinnamon and lavender oils on ftsz gene expression in the staphylococus aureus atcc 29213].this study was designed to determine the effect of lavender and cinnamon oils on ftsz gene expression in staphylococcus aureus atcc 29213. the cinnamon and lavender oils at least partially results from the inhibition of ftsz transcription and disruption of cell division process at the level of the septum synthesis, what is similar to mechanisms of drug action used in anti-staphylococcal therapies. the presented results could be an important background for the further detailed research, which is ...201425508649
flavor chemistry of lemon-lime carbonated beverages.the most potent aroma-active components of sprite (sp), sierra mist (sm), and 7up (7up) were identified. aroma extracts were prepared by liquid–liquid continuous extraction/solvent-assisted flavor evaporation (llce/safe). twenty-eight compounds were detected by gas chromatography–olfactometry (gc-o) with linalool (floral, lavender), octanal (pungent orange), and 2,3-dehydro-1,8-cineole (minty) determined to be predominant aroma compounds based on their high flavor dilution (fd) factors by aroma ...201525494537
the use of aromasticks at a cancer centre: a retrospective audit.to consider the use of aromasticks in a cancer centre in the uk: the reasons for their use, the choice of essential oils used in them and the demographics of the patients to whom they were given.201425486854
sinbase: an integrated database to study genomics, genetics and comparative genomics in sesamum indicum.sesame (sesamum indicum l.) is an ancient and important oilseed crop grown widely in tropical and subtropical areas. it belongs to the gigantic order lamiales, which includes many well-known or economically important species, such as olive (olea europaea), leonurus (leonurus japonicus) and lavender (lavandula spica), many of which have important pharmacological properties. despite their importance, genetic and genomic analyses on these species have been insufficient due to a lack of reference ge ...201525480115
[effect of cinnamon and lavender oils on ftsz gene expression in the staphylococus aureus atcc 29213].this study was designed to determine the effect of lavender and cinnamon oils on ftsz gene expression in staphylococcus aureus atcc 29213. the cinnamon and lavender oils at least partially results from the inhibition of ftsz transcription and disruption of cell division process at the level of the septum synthesis, what is similar to mechanisms of drug action used in anti-staphylococcal therapies. the presented results could be an important background for the further detailed research, which is ...201625474870
preservative activity of lavender hydrosols in moisturizing body gels.the study was undertaken to verify the antimicrobial activity of lavandula angustifolia hydrosols in moisturizing body gels. the inhibition efficacy of four lavender hydrosols (obtained from fresh or dry herbs or flowers) was tested against staphylococcus aureus atcc 6538, escherichia coli atcc 1627, candida sp. łock 0008 and aspergillus niger atcc 16404 in compliance with the standards of the european pharmacopoeia commission. although the tested hydrosols did not express any remarkable antimic ...201525353363
rhamnolipids as emulsifying agents for essential oil formulations: antimicrobial effect against candida albicans and methicillin-resistant staphylococcus aureus.this work examines the influence of essential oil composition on emulsification with rhamnolipids and their use as therapeutic antimicrobial agents against two opportunistic pathogens, methicillin-resistant staphylococcus aureus (mrsa) and candida albicans. rhamnolipids, produced by pseudomonas aeruginosa, with waste frying oil as the carbon source, were composed of eight rhamnolipid homologues. the rhamnolipid mixture was used to produce emulsions containing essential oils (eos) of melaleuca al ...201425269010
deoxyxylulose 5-phosphate reductoisomerase is not a rate-determining enzyme for essential oil production in spike lavender.spike lavender (lavandula latifolia) is an economically important aromatic plant producing essential oils, whose components (mostly monoterpenes) are mainly synthesized through the plastidial methylerythritol 4-phosphate (mep) pathway. 1-deoxy-d-xylulose-5-phosphate (dxp) synthase (dxs), that catalyzes the first step of the mep pathway, plays a crucial role in monoterpene precursors biosynthesis in spike lavender. to date, however, it is not known whether the dxp reductoisomerase (dxr), that cat ...201425151124
carbon partitioning to the terpenoid biosynthetic pathway enables heterologous β-phellandrene production in escherichia coli cultures.escherichia coli was used as a microbial system for the heterologous synthesis of β-phellandrene, a monoterpene of plant origin with several potential commercial applications. expression of lavandula angustifolia β-phellandrene synthase (phls), alone or in combination with picea abies geranyl-diphosphate synthase in e. coli, resulted in no β-phellandrene accumulation, in sharp contrast to observations with phls-transformed cyanobacteria. lack of β-phellandrene biosynthesis in e. coli was attribu ...201425116411
linking bacterial endophytic communities to essential oils: clues from lavandula angustifolia mill.endophytic bacteria play a crucial role in plant life and are also drawing much attention for their capacity to produce bioactive compounds of relevant biotechnological interest. here we present the characterisation of the cultivable endophytic bacteria of lavandula angustifolia mill.-a species used since antiquity for its therapeutic properties-since the production of bioactive metabolites from medical plants may reside also in the activity of bacterial endophytes through their direct productio ...201424971151
antimicrobial efficacy of five essential oils against oral pathogens: an in vitro study.this study was aimed to find out the minimum inhibitory concentration (mic) of five essential oils against oral pathogens and to find out the minimum bactericidal concentration (mbc) and minimum fungicidal concentration (mfc) of five essential oils against oral pathogens.201324966732
ethnobotanical and phytomedical knowledge in the north-western ligurian alps.the ethnobotany of european alpine regions is much diversified and scarcely investigated. these regions retain a well-developed heritage culture and botanical traditional knowledge, favored by the isolated montane location. we carried out a study of therapeutic and traditional uses of native plants of a poorly explored area of the western italian alps in the ligurian region (nw italy). the area has been the object of human activities since prehistoric ages, and an obliged crossroad for people mo ...201424910407
oviposition deterrent and ovicidal activities of seven herbal essential oils against female adults of housefly, musca domestica l.the oviposition deterrent and ovicidal of seven herbal essential oils derived from citrus sinensis, cymbopogon citratus, eucalyptus glubulus, illicium verum, lavandula angustifolia, mentha piperita, and zingiber cussumunar were assessed against the gravid female of housefly, musca domestica l., under laboratory conditions and compared with commercial insecticide (10% w/v cypermethrin). they were assayed at three concentrations (1.0, 5.0, and 10.0%) where plastic cups containing 1 ml of desired o ...201424894080
antibacterial activity against clostridium genus and antiradical activity of the essential oils from different origin.in the present study, the antimicrobial and antiradical activities of 15 essential oils were investigated. the antimicrobial activities were determined by using agar disc diffusion and broth microdilution methods against clostridium genus and antioxidant properties of essential oils by testing their scavenging effect on dpph radicals activities. we determined the antibacterial activity of clostridium butyricum, clostridium hystoliticum, clostridium intestinale, clostridium perfringens and clostr ...201424813985
membrane disruption and anti-quorum sensing effects of synergistic interaction between lavandula angustifolia (lavender oil) in combination with antibiotic against plasmid-conferred multi-drug-resistant escherichia coli.the aim of this study was to investigate the mode of action of the lavender essential oil (lv) on antimicrobial activity against multi-drug-resistant escherichia coli j53 r1 when used singly and in combination with piperacillin.201424779580
insecticidal activity of plant essential oils against the vine mealybug, planococcus ficus.the vine mealybug, planococcus ficus (signoret) (hemiptera: pseudococcidae), is a pest in grape vine growing areas worldwide. the essential oils from the following aromatic plants were tested for their insecticidal activity against p. ficus: peppermint, mentha piperita l. (lamiales: lamiaceae), thyme-leaved savory, satureja thymbra l., lavender, lavandula angustifolia mill, and basil, ocimum basilicum l. essential oils from peels of the following fruits were also tested: lemon, citrus limon l. ( ...201324766523
repellent effectiveness of seven plant essential oils, sunflower oil and natural insecticides against horn flies on pastured dairy cows and heifers.plant essential oils (basil, geranium, balsam fir, lavender, lemongrass, peppermint, pine and tea tree), mixed with either sunflower oil or ethyl alcohol, were applied at 5% concentrations to the sides of holstein cattle. pastured cattle treated with essential oils diluted in sunflower oil had less flies than the untreated control for a 24-h period. however, the essential oil treatments were not significantly different than the carrier oil alone. barn-held heifers treated with essential oils and ...201424382265
biochemical composition and antioxidant properties of lavandula angustifolia miller essential oil are shielded by propolis against uv radiations.uv radiations are principal causes of skin cancer and aging. suntan creams were developed to protect epidermis and derma layers against photodegradation and photooxidation. the addition of antioxidant plant extracts (i.e. essential oil) to sunscreens is habitually performed, to increase their uv protective effects and to contrast pro-radical and cytotoxic compounds present in these solutions. according to these observations, in the present work, the alteration of chemical composition and bioacti ...201424372191
all-natural composite wound dressing films of essential oils encapsulated in sodium alginate with antimicrobial properties.we present natural polymeric composite films made of essential oils (eos) dispersed in sodium alginate (naalg) matrix, with remarkable anti-microbial and anti-fungal properties. namely, elicriso italic, chamomile blue, cinnamon, lavender, tea tree, peppermint, eucalyptus, lemongrass and lemon oils were encapsulated in the films as potential active substances. glycerol was used to induce plasticity and surfactants were added to improve the dispersion of eos in the naalg matrix. the topography, ch ...201424211443
evaluation of biological and chemical insect repellents and their potential adverse effects.plant extracts, particularly plant oils, had been used and were still in use as repellents against mosquitoes. some of them (e.g., lavender, geraniol, and citriodiol) have been notified by the european commission as active substances to be used in repellents, which are categorized as biocides in product type 19. in the literature, it is known that these substances must be added to repellent products in high concentrations (e.g., 20% and more) in order to reach repellent efficacy. therefore, the ...201424142288
multifunctional finishing of cellulosic/polyester blended fabrics.innovative/efficient finishing systems for imparting multi-functional properties to cotton/polyester and viscose/polyester blends were developed. factors affecting the extent of functionalization including type and concentration of the nano-hybrid, i.e. silver nanoparticles/polyvinyl pyrolidone hybrid (ag-np's/pvp) or zinc oxide nanoparticles/hyperbranched polyamide-amine hybrid (zno-np's/hbpaa), concentration of basic blue 9, or chitosan and sequence of treatment using citric acid as cross-link ...201323911516
the in vitro antimicrobial activity of lavandula angustifolia essential oil in combination with other aroma-therapeutic oils.the antimicrobial activity of lavandula angustifolia essential oil was assessed in combination with 45 other oils to establish possible interactive properties. the composition of the selected essential oils was confirmed using gc-ms with a flame ionization detector. the microdilution minimum inhibitory concentration (mic) assay was undertaken, whereby the fractional inhibitory concentration (σfic) was calculated for the oil combinations. when lavender oil was assayed in 1 : 1 ratios with other o ...201323737850
efficacy of herbal essential oils as insecticides against the housefly, musca domestica l.the insecticidal effects of 20 essential oils derived from herbs, were tested against the housefly species musca domestica l. using a susceptibility test. each was applied in ethyl alcohol at concentrations of 1, 5 and 10% (v/v). ten percent concentrations of cymbopogon citratus (lemongrass), mentha piperita (peppermint) and lavandula angustifolia (lavender) oils were the most effective, showing 100% knockdown at 30 and 60 minutes. the kt50 values for c. citratus, m. piperita and l. angustifolia ...201323691628
ingestion toxicity of three lamiaceae essential oils incorporated in protein baits against the olive fruit fly, bactrocera oleae (rossi) (diptera tephritidae).the ingestion toxicity of three lamiaceae essential oils (eos) - hyptis suaveolens, rosmarinus officinalis and lavandula angustifolia - incorporated in protein baits was evaluated against bactrocera oleae, a worldwide pest of olive fruits. in laboratory conditions, all the tested eos showed dose-dependent toxicity on b. oleae, with mortality rates ranging from 12% (eo concentration: 0.01% w:v) to 100% (eo concentration: 1.75% w:v). semi-field results highlighted the toxicity of l. angustifolia a ...201323594314
efficacy of plant essential oils on postharvest control of rots caused by fungi on different stone fruits in vivo.the antifungal activity of plant essential oils was evaluated as postharvest treatment on stone fruit against brown rot and grey mold rot of stone fruit caused by monilinia laxa and botrytis cinerea, respectively. the essential oils from basil (ocimum basilicum), fennel (foeniculum sativum), lavender (lavandula officinalis), marjoram (origanum majorana), oregano (origanum vulgare), peppermint (mentha piperita), rosemary (rosmarinus officinalis), sage (salvia officinalis), savory (satureja montan ...201323575125
antifungal effect of lavender honey against candida albicans , candida krusei and cryptococcus neoformans.monofloral lavender honey samples (n = 30), were analyzed to test antifungal effect against candida albicans, candida krusei, and cryptococcus neoformans. the specific growth rates (μ) showed that all the yeast growths were reduced in the presence of honey. the honey concentration (% w/v) that inhibited 10% of the yeasts growth (x min) ranged from 31.0% (c. albicans), 16.8% (c. krusei) and 23.0% (c. neoformans). a synthetic honey solution was also tested to determine antifungal activity attribut ...201123572800
combination of essential oils and antibiotics reduce antibiotic resistance in plasmid-conferred multidrug resistant bacteria.in this study we investigated the relationship between several selected commercially available essential oils and beta-lactam antibiotics on their antibacterial effect against multidrug resistant bacteria. the antibacterial activity of essential oils and antibiotics was assessed using broth microdilution. the combined effects between essential oils of cinnamon bark, lavender, marjoram, tea tree, peppermint and ampicillin, piperacillin, cefazolin, cefuroxime, carbenicillin, ceftazidime, meropenem ...201323537749
adverse effects of herbal medicines: an overview of systematic reviews.this overview of systematic reviews (srs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (hms). five electronic databases were searched to identify all relevant srs, with 50 srs of 50 different hms meeting our inclusion criteria. most had only minor weaknesses in methods. serious adverse effects were noted only for four hms: herbae pulvis standardisatus, larrea tridentate, piper methysticum and cassia senna. the most severe adverse effects were liver o ...201323472485
potential application of aromatic plant extracts to prevent cheese blowing.this study aimed to inhibit the growth of escherichia coli and clostridium tyrobutyricum, common bacteria responsible for early and late cheese blowing defects respectively, by using novel aqueous extracts obtained by dynamic solid-liquid extraction and essential oils obtained by solvent free microwave extraction from 12 aromatic plants. in terms of antibacterial activity, a total of 13 extracts inhibited one of the two bacteria, and only two essential oils, lavandula angustifolia mill. and lava ...201323417280
the biosynthetic origin of irregular monoterpenes in lavandula: isolation and biochemical characterization of a novel cis-prenyl diphosphate synthase gene, lavandulyl diphosphate synthase.lavender essential oils are constituted predominantly of regular monoterpenes, for example linalool, 1,8-cineole, and camphor. however, they also contain irregular monoterpenes including lavandulol and lavandulyl acetate. although the majority of genes responsible for the production of regular monoterpenes in lavenders are now known, enzymes (including lavandulyl diphosphate synthase (lpps)) catalyzing the biosynthesis of irregular monoterpenes in these plants have not been described. here, we r ...201323306202
effects of inhaled lavender essential oil on stress-loaded animals: changes in anxiety-related behavior and expression levels of selected mrnas and proteins.inhalation of various essential oils elicits behavioral changes as a consequence of a complex centrally coordinated response. to understand the molecular mechanisms of action of aromatic compounds on emotional responses, we evaluated the stress-induced changes in mouse brain and the efficacy of inhaled essential oil from lavandula officinalis (lveo) using two approaches: a behavioral test, and examining the expression levels of selected genes {fast nerve growth factor receptor (ngfr) mrna, activ ...201223285826
investigation of the effectiveness of syzygium aromaticum, lavandula angustifolia and geranium robertianum essential oils in the treatment of acute external otitis: a comparative trial with ciprofloxacin.background: antibiotics and anti-inflammatory agents are the mainstay of acute external otitis (aeo) treatment. the present study investigated the effectiveness of a combination herbal drop (lamigex) composed of essential oils from syzygium aromaticum, lavandula angustifolia, and geranium robertianum in the alleviation of aeo symptoms and compared its effects to those of ciprofloxacin 0.3% drop. methods: seventy patients were randomly assigned to receive ciprofloxacin 0.3% (n = 35) or lamigex (n ...201223274083
efficacy of plant extracts and oils as mosquito repellents.some natural products, extract of achillea millefolium (yarrow), birch/pine tar-, citronella-, clove-, eucalyptus-, geranium-, lavender-, lily of the valley- and peppermint oils have been tested for repellency in the laboratory against aedes aegypti and in the field predominantly against aedes communis and a. cinereus. the laboratory tests showed that yarrow extract exhibited a similar repellency as the reference substances n,n-diethyl-m-toluamide and n,n-diethyl-mandelic acid amide. a good repe ...199823195905
antimicrobial activity of blended essential oil preparation.antimicrobial activities of two blended essential oil preparations comprising lavender oil, petigrain oil, clary sage oil, ylang ylang oil and jasmine oil were evaluated against various pathogenic microorganisms. both preparations showed antimicrobial activity in the agar disc diffusion assay against the gram-positive bacteria, staphylococcus aureus atcc6538 and s. epidermidis isolated strain, the fungus, candida albicans atcc10231, and the gram-negative bacterium, escherichia coli atcc25922, bu ...201223157022
evaluation and validation of two microbiological tests for screening antibiotic residues in honey according to the european guideline for the validation of screening methods.two microbiological kits based on bacillus stearothermophilus (eclipse 50® and premi®test) have been evaluated and validated according to the european guideline for the validation of screening methods (january 2010) and in relation to the concentrations recommended by the eu-rl in 2007. both tests are robust, a fast method and easy to implement. both tests are applicable to a very large variety of honeys from different floral and geographical origins (rosemary, lavender, scrub, heath, alder, for ...201323126529
comparison of chemical composition and antibacterial activity of lavender varieties from poland.the aim of the study was comparing the chemical composition of the essential oils from five varieties of lavender (lavandula angustifolia l.), and its biological activity against two pathogenic bacteria, staphylococcus aureus and pseudomonas aeruginosa. in the comparison we included the following varieties: 'munstead', 'munstead strain', 'lavender lady', 'ellegance purple' and 'blue river'. selected varieties of lavender (l. angustifolia) are characterised by exactly the same main compounds with ...201322989360
extraction of volatile oil from aromatic plants with supercritical carbon dioxide: experiments and modeling.an overview of the studies carried out in our laboratories on supercritical fluid extraction (sfe) of volatile oils from seven aromatic plants: pennyroyal (mentha pulegium l.), fennel seeds (foeniculum vulgare mill.), coriander (coriandrum sativum l.), savory (satureja fruticosa béguinot), winter savory (satureja montana l.), cotton lavender (santolina chamaecyparisus) and thyme (thymus vulgaris), is presented. a flow apparatus with a 1 l extractor and two 0.27 l separators was built to perform ...201222951395
antibacterial and antioxidant potency of floral honeys from different botanical and geographical origins.in order to assess their physicochemical and antioxidant properties as well as their antimicrobial potency, four varieties of honey from different botanical and geographical origins were used. the agar incorporation method was used to determine the antimicrobial potency of honeys. the total phenol content was determined by a modified folin-ciocalteu method and the free radical scavenging activity by the fe(3+)reducing power (frap) assay. manuka honey was the most effective against staphylococcus ...201222948516
the lavender plumage colour in japanese quail is associated with a complex mutation in the region of mlph that is related to differences in growth, feed consumption and body temperature.the lavender phenotype in quail is a dilution of both eumelanin and phaeomelanin in feathers that produces a blue-grey colour on a wild-type feather pattern background. it has been previously demonstrated by intergeneric hybridization that the lavender mutation in quail is homologous to the same phenotype in chicken, which is caused by a single base-pair change in exon 1 of mlph.201222937744
fumigant toxicity of plant essential oils against camptomyia corticalis (diptera: cecidomyiidae).the toxicity of 98 plant essential oils against third instars of cecidomyiid gall midge camptomyia corticalis (loew) (diptera: cecidomyiidae) was examined using a vapor-phase mortality bioassay. results were compared with that of a conventional insecticide dichlorvos. based on 24-h lc50 values, all essential oils were less toxic than dichlorvos (lc50, 0.027 mg/cm3). the lc50 of caraway (carum carvi l.) seed, armoise (artemisia vulgaris l.), clary sage (salvia sclarea l.), oregano (origanum vulga ...201222928313
medicinal lavender modulates the enteric microbiota to protect against citrobacter rodentium-induced colitis.inflammatory bowel disease, inclusive of crohn's disease and ulcerative colitis, consists of immunologically mediated disorders involving the microbiota in the gastrointestinal tract. lavender oil is a traditional medicine used to relieve many gastrointestinal disorders. the goal of this study was to examine the therapeutic effects of the essential oil obtained from a novel lavender cultivar, lavandula×intermedia cultivar okanagan lavender (oleo), in a mouse model of acute colitis caused by citr ...201222821949
antioxidant and antibacterial effects of lavandula and mentha essential oils in minced beef inoculated with e. coli o157:h7 and s. aureus during storage at abuse refrigeration temperature.the essential oils (eos) of lavandula angustifolia l. and mentha piperita l. were analyzed by gas chromatography mass spectrometry (gc/ms). the major constituents were linalool (22.35%), linalyl acetate (21.80%), trans-ocimene (6.16%) and 4-terpineol (5.19%) for l. angustifolia and menthol (33.28%), menthone (22.03%), and menthyl acetate (6.40%) for m. piperita. in vitro antibacterial activity of both eos against escherichia coli o157:h7 and staphylococcus aureus cect 4459 showed high inhibition ...201222789458
anticancer activity of certain herbs and spices on the cervical epithelial carcinoma (hela) cell line.acetone extracts of selected plant species were evaluated for their in vitro cytotoxicity against a noncancerous african green monkey kidney (vero) cell line and an adenocarcinoma cervical cancer (hela) cell line. the plants studied were origanum vulgare l. (oregano), rosmarinus officinalis l. (upright and ground cove rosemary), lavandula spica l. (lavender), laurus nobilis l. (bay leaf), thymus vulgaris l. (thyme), lavandula x intermedia l. (margaret roberts lavender), petroselinum crispum mill ...201222649474
cloning, functional characterization and genomic organization of 1,8-cineole synthases from lavandula.several members of the genus lavandula produce valuable essential oils (eos) that are primarily constituted of the low molecular weight isoprenoids, particularly monoterpenes. we isolated over 8,000 ests from the glandular trichomes of l. x intermedia flowers (where bulk of the eo is synthesized) to facilitate the discovery of genes that control the biosynthesis of eo constituents. the expression profile of these ests in l. x intermedia and its parents l. angustifolia and l. latifolia was establ ...201222592779
nature against depression.depression is a major health problem currently recognized as a leading cause of morbidity worldwide. in the united states alone, depression affects approximately 20% of the population. with current medications suffering from major shortcomings that include slow onset of action, poor efficacy, and unwanted side effects, the search for new and improved antidepressants is ever increasing. in an effort to evade side effects, people have been resorting to popular traditional herbal medicines to relie ...201222414105
antibacterial activity of thyme and lavender essential oils.strong antiseptic activity of essential oils has been known for a long time. the antibacterial activity of oils was tested against clinical bacterial strains of staphylococcus, enterococcus, escherichia and pseudomonas genera. the agar diffusion method was used for microbial growth inhibition at various concentrations of the oils from t. vulgaris and l. angustifolia. susceptibility testing to antibiotics and chemotherapeutics was carried out using disc-diffusion method. 120 strains of bacteria i ...201122313307
xanthine oxidase inhibitory activity of the methanolic extracts of selected jordanian medicinal plants.the search for novel xanthine oxidase (xo) inhibitors with a higher therapeutic activity and fewer side effects are desired not only to treat gout but also to combat various other diseases associated with the xo activity. at present, the potential of developing successful natural products for the management of xo-related diseases is still largely unexplored. in the present study, we have screened the methanolic extracts of various jordanian medicinal plants for their xo inhibitory activities usi ...201122262935
interspecies comparison of chemical composition and anxiolytic-like effects of lavender oils upon inhalation.essential oils have traditionally been used for decades to alleviate the symptoms of various mental problems. in terms of anxiolytic-like properties, lavender oil is probably the most commonly used and best-studied essential oil. although there is compositional variance among the oils extracted from different origins, there have been few studies performed to date to investigate how these differences affect the expression of anxiolytic-like activity. this paper discusses the interspecies differen ...201122224307
Genetic differences in temperament determine whether lavender oil alleviates or exacerbates anxiety in sheep.Growing concerns about the risk of addiction to benzodiazepines have led to increasing interest in alternative therapies to treat anxiety and depression. Lavender oil (Lavendula augustifolia) is reportedly anxiolytic in a number of species but little is known about how it affects individuals that are more or less anxious when faced with a stressor. In this study, we used changes in locomotor activity and the plasma concentrations of cortisol to test whether lavender oil would reduce behavioral a ...201122192707
Anti-inflammatory, anti-oxidant, and apoptotic activities of four plant species used in folk medicine in the Mediterranean basin.The aim of this research was to study the potential anti-inflammatory activity of myrtle (Myrtus communis), sarsaparilla (Smilax aspera), Arabian or French lavender (Lavandula stoechas), and calamint (Calamintha nepeta) along with their apoptotic effects on the pro-inflammatory cells, and the correlation of these effects with the plants' potential anti-oxidant activity. Myrtle extract exhibited the highest inhibitory activity in the paw oedema induced by carrageenan (60% at 3 h), whereas calamin ...201222186311
[Sensitivity assessment of thyme and lavender essential oils against clinical strains of Escherichia coli for their resistance].Strong antiseptic activity of plant essential oils and extracts has been known for a long time. The antibacterial activity of thyme and lavender essential oils were tested against 30 clinical bacterial strains of Escherichia coli from patients with different clinical conditions. The agar diffusion method was used for microbial growth inhibition at various concentrations of the oils from Thymus vulgaris and Lavandula angustifolia. Susceptibility testing to antibiotics and chemotherapeutics was ca ...201122184923
Toxicity of essential and non-essential oils against the chewing louse, Bovicola (Werneckiella) ocellatus.The toxicity of six plant essential oils to the chewing louse, Bovicola (Werneckiella) ocellatus collected from donkeys, was examined in laboratory bioassays. The oils examined were: tea-tree (Melaleuca alternifolia), lavender (Lavandula angustifolia), peppermint (Mentha piperita), eucalyptus (Eucalyptus globulus Labillardiere), clove bud (Eugenia caryophyllata) and camphor (Cinnamomum camphora). All except camphor oil showed high levels of toxicity, with significant dose-dependent mortality and ...201122177577
subconscious olfactory influences of stimulant and relaxant odors on immune function.brain and immune system are linked by bidirectional pathways so that changes of the central nervous system may influence various immune functions. the olfactory system may be involved in this interaction. in most odor studies subjects are aware of an odor exposure, using frequently high odor concentrations or long-term exposures without controls. in this pilot study, the potential immune effects of short-term odor exposure were examined in 32 blinded subjects (16 male, 16 female). subjects were ...201122159968
A large foodborne outbreak of norovirus in diners at a restaurant in England between January and February 2009.SUMMARYAn outbreak of gastroenteritis affected at least 240 persons who had eaten at a gourmet restaurant over a period of 7 weeks in 2009 in England. Epidemiological, microbiological, and environmental studies were conducted. The case-control study demonstrated increased risk of illness in those who ate from a special 'tasting menu' and in particular an oyster, passion fruit jelly and lavender dish (odds ratio 7·0, 95% confidence interval 1·1-45·2). Ten diners and six staff members had laborato ...201122129511
evaluation of the effects of plant-derived essential oils on central nervous system function using discrete shuttle-type conditioned avoidance response in mice.although plant-derived essential oils (eos) have been used to treat various mental disorders, their central nervous system (cns) acting effects have not been clarified. the present study compared the effects of 20 kinds of eos with the effects of already-known cns acting drugs to examine whether the eos exhibited cns stimulant-like effects, cns depressant-like effects, or neither. all agents were tested using a discrete shuttle-type conditioned avoidance task in mice. essential oils of peppermin ...201122086772
Displaying items 1 - 100 of 368