Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| perioperative pharmacokinetics and pharmacodynamics of meloxicam in emus (dromaius novaehollandiae) of different age groups using nonlinear mixed effect modelling. | meloxicam is a widely used nonsteroidal anti-inflammatory drug in avian species. however, variability in pharmacokinetic (pk) and pharmacodynamic (pd) parameters in birds warrants species-specific studies for dose and dosing interval optimization. we performed a perioperative pk study of meloxicam (0.5 mg/kg, intravenously) on emus of three different age groups: 3 chicks (5 weeks old, 3.5 kg), 4 juveniles (26 weeks old, 18.8 kg) and 6 adults (66 weeks old, 38.8 kg). a two-compartment population ... | 2020 | 33141479 |
| development of 49 novel microsatellite markers from next-generation sequencing data and a robust method for parentage tests in the emu (dromaius novaehollandiae). | the emu is a useful and new breed of poultry, but their genetic improvement has not advanced yet due to their very recent domestication. pedigree information is difficult to record because of their complex reproduction system (polyandry). to identify parent-offspring relationships in the emu, parentage test based on polymorphic dna markers have to be developed. in this study, we isolated more than 25,000 microsatellite (simple sequence repeat, ssr) regions from next-generation sequencing data vi ... | 2020 | 33068676 |
| natural infection by procyrnea uncinipenis (nematoda, habronematidae), a parasite from rheas, an autoctone bird from south america, in emus dromaius novaehollandiae, a ratite from new zealand. | the present study reports a natural infection of emus, dromaius novaehollandiae, by the nematode procyrnea uncinipenis. five adult emus from a scientific breeding farm at north fluminense state university located in the city of campos dos goytacazes, rio de janeiro state, brazil were necropsied, and their gastrointestinal tract were collected and examined for the presence of parasites from october 2013 to november 2015. two of the five (40%) emus necropsied were infected with nematodes, and a po ... | 2020 | 33024210 |
| anisotropic fracture resistance of avian eggshell. | in order to understand the fracture toughness anisotropy of avian eggshells, we have investigated eggshells of the emu (dromaius novaehollandiae) whereby the large size (~13 cm × 9.5 cm) enabled the fabrication of beam samples in various orientations. the emu eggshell was found to have a hierarchical microstructure similar to chicken eggshell, with the only significant difference being the absence of a continuous cuticle layer. emu eggshell was found to have significantly lower strength when sam ... | 2020 | 32957195 |
| serological evidence of avian influenza in captive wild birds in a zoo and two safari parks in bangladesh. | avian influenza (ai) is endemic and frequently causes seasonal outbreaks in winter in bangladesh due to high pathogenic avian influenza (hpai) h5n1 and low pathogenic avian influenza (lpai) h9n2. among avian influenza a viruses (aiv), h5, h7, and h9 subtypes have the most zoonotic potential. captive birds in zoos and safari parks are used for educational, recreational, breeding, and conservational purposes in bangladesh. to screen for aiv in captive birds to assess potential public health threat ... | 2020 | 32882787 |
| putative adult neurogenesis in palaeognathous birds: the common ostrich (struthio camelus) and emu (dromaius novaehollandiae). | in the current study, we examined adult neurogenesis throughout the brain of the common ostrich (struthio camelus) and emu (dromaius novaehollandiae) using immunohistochemistry for the endogenous markers pcna which labels proliferating cells, and dcx, which stains immature and migrating neurons. the distribution of pcna and dcx labelled cells was widespread throughout the brain of both species. the highest density of cells immunoreactive to both markers was observed in the olfactory bulbs and th ... | 2020 | 32767787 |
| impacts of exclusion fencing on target and non-target fauna: a global review. | exclusion fencing is a common tool used to mitigate a variety of unwanted economic losses caused by problematic wildlife. while the potential for agricultural, ecological and economic benefits of pest animal exclusion are often apparent, what is less clear are the costs and benefits to sympatric non-target wildlife. this review examines the use of exclusion fencing in a variety of situations around the world to elucidate the potential outcomes of such fencing for wildlife and apply this knowledg ... | 2020 | 32725786 |
| the influence of age and gender on emu (dromaius novaehollandiae) fat. | studies were carried out to determine the influence of age and sex on two types of fat (back fat and abdominal fat) in the emu, as these are factors that influence the composition of animal tissues. the material involved 26 emus at the age 1 (6 males), 3 (6 males) and 15 years (8 females and 6 males), kept on the same farm and fed the feed of the same nutritional value. the basic chemical composition, cholesterol and mineral content, as well as fatty acid profile of back and abdominal fat of emu ... | 2020 | 32632331 |
| osteological description of casque ontogeny in the southern cassowary (casuarius casuarius) using micro-ct imaging. | extant cassowaries (casuarius) are unique flightless birds found in the tropics of indo-australia. they have garnered substantial attention from anatomists with focus centered on the bony makeup and function of their conspicuous cranial casques, located dorsally above the orbits and neurocranium. the osteological patterning of the casque has been formally described previously; however, there are differing interpretations between authors. these variable descriptions suggest that an anatomical und ... | 2020 | 32558300 |
| mitochondrial dna variations in japanese farmed emu populations. | the emu (dromaius novaehollandiae) is a new poultry. in this study, we investigated the haplotype composition of mitochondrial dna among emu populations farmed in japan. we sequenced the d-loop region in 109 individuals, and detected four substitution sites and three haplotypes (hap-a, -b, and -c). hap-a was the most frequently observed haplotype in the japanese populations. although hap-c was a rare haplotype in not only japanese but also australian populations, it was detected with high freque ... | 2020 | 32249252 |
| sequence comparisons of cytochrome p450 aromatases from australian animals predict differences in enzymatic activity and/or efficiency†. | aromatase (p450arom, cyp19a1) is the terminal enzyme in the synthesis of the steroid hormone family of estrogens. not surprisingly, this enzyme has structural similarities between the limited number of species studied thus far. this study examined the structure of aromatases from four diverse australian species including a marsupial (tammar wallaby; macropus eugenii), monotreme (platypus; ornithorhynchus anatinus), ratite (emu; dromaius novaehollandiae) and lizard (bearded dragon; pogona vittice ... | 2020 | 32179898 |
| development and characterization of ten novel microsatellite loci for the emu (dromaius novaehollandiae) and genetic diversity of japanese farm populations. | the emu (dromaius novaehollandiae) is a useful poultry animal farmed for fat, meat, and eggs. genetic structure and relationships among farmed emu populations in japan are unknown and the number of microsatellite markers for genetic analysis of the emu is insufficient. in this study, we isolated 16 microsatellites from the emu genome and developed ten new microsatellite markers. these microsatellite markers were used to characterize three farm emu populations in japan. the number of alleles rang ... | 2020 | 32086719 |
| attenuated fgf signaling underlies the forelimb heterochrony in the emu dromaius novaehollandiae. | powered flight was fundamental to the establishment and radiation of birds. however, flight has been lost multiple times throughout avian evolution. convergent losses of flight within the ratites (flightless paleognaths, including the emu and ostrich) often coincide with reduced wings. although there is a wealth of anatomical knowledge for several ratites, the genetic mechanisms causing these changes remain debated. here, we use a multidisciplinary approach employing embryological, genetic, and ... | 2019 | 31668620 |
| prevalence of anti-toxoplasma gondii antibodies in ratites from brazil. | the prevalence of anti-toxoplasma gondii antibodies was investigated among 104 ratites: 68 rheas (rhea americana), 16 emus (dromaius novaehollandiae), and 20 ostriches (struthio camelus) in 4 brazilian states. the prevalence in rheas was 26.5% (18 of 68), and titers were 1:100 (n = 8), 1:200 (n = 1), 1:400 (n = 4), 1:800 (n = 4), and 1:1,600 (n = 1). in emus, the prevalence was 50% (8 of 16), and titers were 1:50 (n = 1) and 1:100 (n = 7). the ostriches were slaughtered for human consumption, an ... | 2019 | 31584862 |
| evolution of the avian digital pattern. | variation in digit number has occurred multiple times in the history of archosaur evolution. the five digits of dinosaur limbs were reduced to three in bird forelimbs, and were further reduced in the vestigial forelimbs of the emu. regulation of digit number has been investigated previously by examining genes involved in anterior-posterior patterning in forelimb buds among emu (dromaius novaehollandiae), chicken (gallus gallus) and zebra finch (taeniopygia guttata). it was described that the exp ... | 2019 | 31189916 |
| gastrointestinal parasites of a population of emus (dromaius novaehollandiae) in brazil. | emus are large flightless birds in the ratite group and are native to australia. since the mid-1980s, there has been increased interest in the captive breeding of emus for the production of leather, meat and oil. the aim of this study was to identify gastrointestinal parasites in the feces of emus dromaius novaehollandiae from a south american scientific breeding. fecal samples collected from 13 birds were examined by direct smears, both with and without centrifugation, as well as by the fecal f ... | 2020 | 31116295 |
| ticks in wild animals at a resort and the first documentation of amblyomma sculptum infesting emu (dromaius novaehollandiae). | the study aimed to identify species of ticks present in the environment and among captive animals, in mangaratiba, rio de janeiro, brazil. ticks were isolated from captive animals by manual examination and free-living ticks in the environment were captured using the flannel drag technique. a total of 91 ticks were obtained (51 adults, 25 nymphs and 15 larvae). the specimens were identified morphologically as amblyomma sp., amblyomma dubitatum, amblyomma ovale and amblyomma sculptum , and were di ... | 2019 | 30810663 |
| retrospective study of mortality in captive struthioniformes in a french zoo (1974-2015). | the husbandry and medical records, and necropsy reports, of 1,002 captive struthioniformes that died at the réserve africaine de sigean (france) from 1974 to 2015 were examined. the goal of this study was to determine the most common causes of mortality in ostriches ( struthio camelus), emus ( dromaius novaehollandiae), and american rheas ( rhea americana), in order to highlight common causes of mortality, as well as the influence of age, gender, and rearing methods on mortality. the most preval ... | 2018 | 30592921 |
| avian lungs: a novel scaffold for lung bioengineering. | allogeneic lung transplant is limited both by the shortage of available donor lungs and by the lack of suitable long-term lung assist devices to bridge patients to lung transplantation. avian lungs have different structure and mechanics resulting in more efficient gas exchange than mammalian lungs. decellularized avian lungs, recellularized with human lung cells, could therefore provide a powerful novel gas exchange unit for potential use in pulmonary therapeutics. to initially assess this in bo ... | 2018 | 29949597 |
| genetic diversity and drivers of dwarfism in extinct island emu populations. | australia's iconic emu (dromaius novaehollandiae novaehollandiae) is the only living representative of its genus, but fossil evidence and reports from early european explorers suggest that three island forms (at least two of which were dwarfs) became extinct during the nineteenth century. while one of these-the king island emu-has been found to be conspecific with australian mainland emus, little is known about how the other two forms-kangaroo island and tasmanian emus-relate to the others, or e ... | 2018 | 29618519 |
| ovarian teratocarcinoma in an emu (dromaius novaehollandiae): histopathological and immunohistochemical characterization. | a 17-year-old female emu (dromaius novaehollandiae) was presented for clinical evaluation due to a 3-week history of anorexia and progressive weight loss. the emu died after sedation. at necropsy examination, the ovary and the majority of the oviduct were effaced by a multinodular cystic mass and accompanied by 6 l of coelomic effusion. histopathology revealed a neoplasm composed of well-differentiated, poorly organized tissues derived from ectoderm, mesoderm and endoderm. tissues within the neo ... | 2018 | 29599003 |
| a simplified protocol for molecular sexing in the emu (dromaius novaehollandiae). | male and female emus are nearly identical both as chicks and as adults. although morphological differences of the internal genital tract can be used to distinguish the sexes, a high degree of diagnostic skill is required for accurate sexing. dna-based sexing methods are highly accurate and can be used to diagnose sex without requiring a high degree of technical skill. however, conventional pcr-rflp is time consuming and costly, requiring the digestion of pcr products. in this study, we simplifie ... | 2018 | 29300990 |
| mucopolysaccharidosis iiib (sanfilippo syndrome b) in a commercial emu (dromaius novaehollandiae) flock. | clinicopathological diagnosis of mucopolysaccharidosis type iiib (mps iiib; sanfilippo syndrome b), an inherited autosomal recessive lysosomal storage disease, as a cause of losses in a commercial emu flock and screening breeders using a mutation-specific dna test are described. between 2012 and 2015, ∼5-10 juvenile emus from a few weeks to several months of age developed progressive neurological signs and died while others in the flock remained healthy. necropsy of two affected siblings reveale ... | 2018 | 28911234 |
| aquatic bird bornavirus 1 infection in a captive emu (dromaius novaehollandiae): presumed natural transmission from free-ranging wild waterfowl. | an adult female emu (dromaius novaehollandiae) presented with anorexia, maldigestion, weight loss, and various subtle nervous deficits. after four months of unrewarding diagnostics, treatments, and supportive care, the emu was euthanized due to lack of clinical improvement and progressive weight loss. gross pathology revealed a very narrow pylorus and multiple flaccid diverticula of the small intestines. histopathological findings included severe lymphoplasmacytic encephalomyelitis and multifoca ... | 2017 | 28862888 |
| the first record of infestation by a native tick (acari: ixodidae) on the australian emu (dromaius novaehollandiae) and a review of tick paralysis in australian birds. | for the first time, infestation of the australian emu by a native tick is recorded based on an engorged adult female specimen of the southern paralysis tick (ixodes cornuatus) taken from a captive emu at healesville sanctuary, victoria, australia. tick paralysis in australian birds is discussed. | 2017 | 28849543 |
| seasonal and daily changes in the behaviour of the adult emu (dromaius novaehollandiae) under farm conditions. | 1. the aim of this study was to present selected elements of emu behaviour in three different seasons (the non-breeding season, the pre-breeding season and the breeding season) and in the morning and afternoon. the study focused on feed, water and sand intake; plumage care; resting; agonistic behaviour and other activities, mostly standing still, aimless walking or observing the surroundings. 2. the troop consisted of 11 emus (5 females and 6 males) aged 12 years, kept in a free-range system. ob ... | 2017 | 28604099 |
| surfactant-assisted synthesis of polythiophene/ni0.5zn0.5fe2-xcexo4 ferrite composites: study of structural, dielectric and magnetic properties for emi-shielding applications. | this work reports the exploitation of nanocrystalline ni0.5zn0.5fe2-xcexo4 ferrite for potential application by designing quasi-spherical shaped polythiophene (pth) composites via in situ emulsion polymerization. the structural, electronic, dielectric, magnetic, and electromagnetic interference (emi) shielding properties of pth/ni0.5zn0.5fe2-xcexo4 composites were investigated. our results suggest that these properties could be optimized by modulating the concentration of x (composition) in the ... | 2017 | 28397906 |
| sustained release of anticancer agent phytic acid from its chitosan-coated magnetic nanoparticles for drug-delivery system. | chitosan (cs) iron oxide magnetic nanoparticles (mnps) were coated with phytic acid (pta) to form phytic acid-chitosan-iron oxide nanocomposite (pta-cs-mnp). the obtained nanocomposite and nanocarrier were characterized by powder x-ray diffraction, fourier transform infrared spectroscopy, vibrating sample magnetometry, transmission electron microscopy, and thermogravimetric and differential thermogravimetric analyses. fourier transform infrared spectra and thermal analysis of mnps and pta-cs-mnp ... | 2017 | 28392693 |
| search for ferromagnetic order in overdoped copper-oxide superconductors. | in copper-oxides that show high-temperature superconductivity (hts), the critical temperature (tc) has a dome-shaped doping dependence. the cause of demise of both tc and superfluid density ns on the overdoped side is a major puzzle. a recent study of transport and diamagnetism in a large number of overdoped la2-xsrxcuo4 (lsco) films shows that this cannot be accounted for by disorder within the conventional bardeen-cooper-schrieffer theory. this brings to focus an alternative explanation - comp ... | 2017 | 28378795 |
| picky eaters are rare: dna-based blood meal analysis of culicoides (diptera: ceratopogonidae) species from the united states. | biting midges in the genus culicoides (diptera; ceratopogonidae) have been implicated in the transmission of a number of parasites and highly pathogenic viruses. in north america, the complete transmission cycles of many of these pathogens need further elucidation. one way to increase our knowledge about the evolution and ecology of culicoides species and the pathogens they transmit is to document the diversity of vertebrate hosts that culicoides feed upon. our objective was to identify the dive ... | 2017 | 28376843 |
| meissner effect measurement of single indium particle using a customized on-chip nano-scale superconducting quantum interference device system. | as many emergent phenomena of superconductivity appear on a smaller scale and at lower dimension, commercial magnetic property measurement systems (mpmss) no longer provide the sensitivity necessary to study the meissner effect of small superconductors. the nano-scale superconducting quantum interference device (nano-squid) is considered one of the most sensitive magnetic sensors for the magnetic characterization of mesoscopic or microscopic samples. here, we develop a customized on-chip nano-sq ... | 2017 | 28374779 |
| myc enhances b-cell receptor signaling in precancerous b cells and confers resistance to btk inhibition. | dysregulation of the oncogenic transcription factor myc induces b-cell transformation and is a driver for b-cell non-hodgkin lymphoma (b-nhl). myc overexpression in b-nhl is associated with more aggressive phenotypes and poor prognosis. although genomic studies suggest a link between myc overexpression and b-cell receptor (bcr) signaling molecules in b-nhl, signaling pathways essential to myc-mediated b-cell transformation have not been fully elucidated. we utilized intracellular phospho-flow cy ... | 2017 | 28368423 |
| synthesis of zn(ii)-doped magnetite leaf-like nanorings for efficient electromagnetic wave absorption. | we report the thermal annealing-induced formation of ring-like structure of zn(ii)-doped magnetite from iron alkoxide leaf-like nanoplate precusor. the phase, structure and morphology of magnetite nanorings were comprehensively characterized by powder x-ray diffraction, x-ray photoelectron spectroscopy, atomic force microscope, scanning electron microscope, and transmission electron microscope. the obtained zn(ii)-doped magnetite nanorings are of 13-20 nm in edge width, 70-110 nm in short axis l ... | 2017 | 28368010 |
| the synthesis of size-adjustable superparamagnetism fe3o4 hollow microspheres. | one hundred fifty to 300-nm-sized monodisperse iron oxide (fe3o4) hollow microspheres were synthesized by the one-pot hydrothermal method. the morphology and crystal structure of the as-prepared hollow microspheres was characterized by scanning electron microscopy, x-ray diffraction, transmission electron microscopy, and high-resolution transmission electron microscopy, while the magnetic property was investigated by vibrating sample magnetometer. we found that the particle size of the hollow mi ... | 2017 | 28363235 |
| eμ and 3'rr igh enhancers show hierarchic unilateral dependence in mature b-cells. | enhancer and super-enhancers are master regulators of cell fate. while they act at long-distances on adjacent genes, it is unclear whether they also act on one another. the immunoglobulin heavy chain (igh) locus is unique in carrying two super-enhancers at both ends of the constant gene cluster: the 5'eμ super-enhancer promotes vdj recombination during the earliest steps of b-cell ontogeny while the 3' regulatory region (3'rr) is essential for late differentiation. since they carry functional sy ... | 2017 | 28348365 |
| magnetism of amorphous and nano-crystallized dc-sputter-deposited mgo thin films. | we report a systematic study of room-temperature ferromagnetism (rtfm) in pristine mgo thin films in their amorphous and nano-crystalline states. the as deposited dc-sputtered films of pristine mgo on si substrates using a metallic mg target in an o₂ containing working gas atmosphere of (n₂ + o₂) are found to be x-ray amorphous. all these films obtained with oxygen partial pressure (po₂) ~10% to 80% while maintaining the same total pressure of the working gas are found to be ferromagnetic at roo ... | 2013 | 28348346 |
| structural and magnetic response in bimetallic core/shell magnetic nanoparticles. | bimagnetic monodisperse cofe₂o₄/fe₃o₄ core/shell nanoparticles have been prepared by solution evaporation route. to demonstrate preferential coating of iron oxide onto the surface of ferrite nanoparticles x-ray diffraction (xrd), high resolution transmission electron microscope (hr-tem) and raman spectroscopy have been performed. xrd analysis using rietveld refinement technique confirms single phase nanoparticles with average seed size of about 18 nm and thickness of shell is 3 nm, which corrobo ... | 2016 | 28335200 |
| an evaluation of the major factors influencing the removal of copper ions using the egg shell (dromaius novaehollandiae): chitosan (agaricus bisporus) composite. | rapid industrialisation, technological development, urbanization and increase in population in the recent past coupled with unplanned and unscientific disposal methods led to increased heavy metal levels in water. realizing the need for development of eco-friendly and cost effective methods, the present investigation was done for the adsorptive removal of copper from aqueous solutions with dromaius novaehollandiae eggshell and chitosan composite. by one variable at a time method, the optimum con ... | 2016 | 28330153 |
| differences in the melanosome distribution within the epidermal melanin units and its association with the impairing background of leukoderma in vitiligo and halo nevi: a retrospective study. | skin color is determined by the number of melanin granules produced by melanocytes that are transferred to keratinocytes. melanin synthesis and the distribution of melanosomes to keratinocytes within the epidermal melanin unit (emu) within the skin of vitiligo patients have been poorly studied. the ultrastructure and distribution of melanosomes in melanocytes and surrounding keratinocytes in perilesional vitiligo and normal skin were investigated using transmission electron microscopy (tem). fur ... | 2017 | 28314912 |
| desulfurization with thialkalivibrio versutus immobilized on magnetic nanoparticles modified with 3-aminopropyltriethoxysilane. | thialkalivibrio versutus d301 cells were immobilized on fe3o4 nanoparticles (nps) synthesized by an improved chemical coprecipitation method and modified with 3-aminopropyltriethoxysilane (aptes), then the immobilized cells were used in sulfur oxidation. | 2017 | 28299545 |
| bony pits in the ostrich (struthio camelus) and emu (dromaius novaehollandiae) bill tip. | a specialized region of the bill tip characterized by a complex arrangement of mechanoreceptors and referred to as a bill tip organ, has been identified in numerous avians. a bill tip organ was initially inferred in kiwi species by the presence of numerous, bony pits in the rostrum of the bill, and later confirmed histologically. this study enumerates and compares the number and distribution of pits present in the bill tip in the ostrich and emu. the heads from 10 ostrich and 5 emu were prepared ... | 2017 | 28296166 |
| ifn-γ directly inhibits murine b-cell precursor leukemia-initiating cell proliferation early in life. | the early-life immune environment has been implicated as a modulator of acute lymphoblastic leukemia (all) development in children, with infection being associated with significant changes in all risk. furthermore, polymorphisms in several cytokine genes, including il-10 and ifn-γ, are associated with leukemia development. however, the mechanisms and timing of these influences remain unknown. here, we use the eμ-ret transgenic mouse model of b-cell precursor all to assess the influence of ifn-γ ... | 2017 | 28295300 |
| ferromagnetic-antiferromagnetic coupling by distortion of fe/mn oxygen octahedrons in (bifeo3 )m (la0.7 sr0.3 mno3 )n superlattices. | interface enhanced magnetism attracts much attention due to its potential use in exploring novel structure devices. nevertheless, the magnetic behavior at interfaces has not been quantitatively determined. in this study, abnormal magnetic moment reduction is observed in la0.7 sr0.3 mno3 (lsmo)/bifeo3 (bfo) superlattices, which is induced by ferromagnetic (fm)/antiferromagnetic (afm) coupling in the interface. with reduced repetition of the superlattice's unit cell [(lsmo)n /(bfo)n ]60/n (n = 1, ... | 2017 | 28294569 |
| caregiver-reported religious beliefs and complementary and alternative medicine use among children admitted to an epilepsy monitoring unit. | complementary and alternative medicine (cam) includes a wide range of practices and products that are generally outside the use of conventional medicine as practiced in western cultures. use of cam in persons with epilepsy is high, even compared to individuals with other chronic health conditions. in this study, we surveyed caregivers of children admitted to a regional epilepsy monitoring unit (emu) in the southeast united states to assess cam use among patients (n=225). thirteen percent of resp ... | 2017 | 28285234 |
| synthesis of a smart ph-responsive magnetic nanocomposite as high loading carrier of pharmaceutical agents. | to create facile external controlled drug delivery system, a magnetic porous carrier based on tin oxide nanoparticles was synthesized by an inexpensive and versatile hydrothermal strategy and used for in-vitro process. magnetic nanocomposites were qualified by fourier transform infrared (ftir), scanning electron microscopy (sem), x-ray diffraction (xrd), vibrational sample magnetometer (vsm) and transmission electron microscopy (tem). results showed that nanoparticles were synthesized successful ... | 2017 | 28284933 |
| facile preparation of hexadecyl-functionalized magnetic core-shell microsphere for the extraction of polychlorinated biphenyls in environmental waters. | alkyl moieties which can retain target analytes due to their lipophilicity are important in sample preparation. in this work, hexadecyl-functionalized magnetic core-shell microspheres (fe3o4@sio2-c16) was successfully prepared by one-pot sol-gel method and used for magnetic solid-phase extraction of polychlorinated biphenyls (pcbs) in environmental water samples. optimized preparation method was achieved by altering the adding moment of hexadecyl-silane. the resultant materials were systematical ... | 2017 | 28283719 |
| characterization of ferromagnetic sludge-based activated carbon and its application in catalytic ozonation of p-chlorobenzoic acid. | in order to solve the separation problem of powdered sludge-based activated carbon (sac), a series of novel ferromagnetic sludge-based activated carbons (fmsacs, with different iron content 2.3, 4.3, and 9.5 wt%) with a good magnetic separation ability were prepared through co-precipitation method in this study. the structure and physicochemical properties of fmsacs and their catalytic ozonation performance on the removal of p-chlorobenzoic acid (p-cba) were investigated. the saturation magnetiz ... | 2017 | 28281060 |
| expression profiling of circulating mirnas in mouse serum in response to echinococcus multilocularis infection. | echinococcus multilocularis is a most pathogenic zoonotic tapeworm that causes devastating echinococcosis in both humans and animals. circulating micrornas (mirnas) are stably existed in the serum/plasma of mammalian hosts during helminthic infection. in this study, we compared the host-circulating mirna expression in the sera from the e. multilocularis-infected and uninfected mice. a total of 58 host-origin serum mirnas were differentially expressed (2 ⩾ fold change, p < 0·05), of which 21 were ... | 2017 | 28270244 |
| odacci: ontology-guided data curation for multisite clinical research data integration in the ninds center for sudep research. | sudden unexpected death in epilepsy (sudep) is the leading mode of epilepsy-related death. the center for sudep research (csr) is an ninds-funded center without wall's initiative aimed at prospectively creating a comprehensive clinical research resource for sudep. this resource consists of a growing set of data and biological samples of a statistically significant cohort of patients at an elevated risk, best represented by the epilepsy monitoring unit (emu) patient population. the informatics an ... | 2016 | 28269839 |
| personalization of noneeg-based seizure detection systems. | seizures affect each patient differently, so personalization is a vital part of developing a reliable noneeg based seizure detection system. this personalization must be done while the patient is undergoing video eeg monitoring in an epilepsy monitoring unit (emu) because seizure detection by eeg is considered to be the ground truth. we propose the use of confidence interval analysis for determining how many seizures must be captured from a patient before we can reliably personalize such a seizu ... | 2016 | 28269701 |
| high magnetisation, monodisperse and water-dispersible cofe@pt core/shell nanoparticles. | high magnetisation and monodisperse cofe alloy nanoparticles are desired for a wide range of biomedical applications. however, these cofe nanoparticles are prone to oxidation, resulting in the deterioration of their magnetic properties. in the current work, cofe alloy nanoparticles were prepared by thermal decomposition of cobalt and iron carbonyls in organic solvents at high temperatures. using a seeded growth method, we successfully synthesised chemically stable cofe@pt core/shell nanostructur ... | 2017 | 28267161 |
| gold nanorod@iron oxide core-shell heterostructures: synthesis, characterization, and photocatalytic performance. | iron oxides are directly coated on the surface of cetyl-trimethylammonium bromide (ctab)-capped gold nanorods (aunrs) in aqueous solutions at room temperature, which results in aunr@fe2o3, aunr@fe3o4, and aunr@fe2o3@fe3o4 core-shell heterostructures. the iron oxide shells are uniform, smooth, with characteristic porous structure, and their thickness can be readily tuned. the shell formation is highly dependent on the reaction parameters including ph and ctab concentration. the fe2o3 shell is amo ... | 2017 | 28262898 |
| manganese mono-boride, an inexpensive room temperature ferromagnetic hard material. | we synthesized orthorhombic feb-type mnb (space group: pnma) with high pressure and high temperature method. mnb is a promising soft magnetic material, which is ferromagnetic with curie temperature as high as 546.3 k, and high magnetization value up to 155.5 emu/g, and comparatively low coercive field. the strong room temperature ferromagnetic properties stem from the positive exchange-correlation between manganese atoms and the large number of unpaired mn 3d electrons. the asymptotic vickers ha ... | 2017 | 28262805 |
| genomic characterisation of eμ-myc mouse lymphomas identifies bcor as a myc co-operative tumour-suppressor gene. | the eμ-myc mouse is an extensively used model of myc driven malignancy; however to date there has only been partial characterization of myc co-operative mutations leading to spontaneous lymphomagenesis. here we sequence spontaneously arising eμ-myc lymphomas to define transgene architecture, somatic mutations, and structural alterations. we identify frequent disruptive mutations in the prc1-like component and bcl6-corepressor gene bcor. moreover, we find unexpected concomitant multigenic lesions ... | 2017 | 28262675 |
| aberrant immunological synapses driven by leukemic antigen-presenting cells. | aberrant immune synapse formation between antigen-presenting and immune effector cells is a central mediator of immune dysfunction and can be observed across several haematologic malignancies. here, we describe the cell preparation, conjugation and immune synapse quantification of b and t cells obtained from patients with leukaemia and the adaptions required when using cells from murine models of disease. | 2017 | 28255724 |
| preparation of porous γ-fe2o3@mwo3 multifunctional nanoparticles for drug loading and controlled release. | we constructed a novel mesoporous wo3 shell layered γ-fe2o3@mwo3 (m was short for mesoporous) core-shell structured drug nano-carrier to investigate loading and controllable release properties of ibuprofen (ibu). this nanocomposite composed of mesoporous wo3 shell with magnetic γ-fe2o3 core. they possesses high surface area of 100.09 m2/g, provides large accessible pore diameter of 6.0 nm for adsorption of drug molecules, high magnetization saturation value of 43.6 emu/g for drug targeting under ... | 2017 | 28240176 |
| simultaneous enhancement of magnetic and mechanical properties in ni-mn-sn alloy by fe doping. | both magnetic-field-induced reverse martensitic transformation (mfirmt) and mechanical properties are crucial for application of ni-mn-sn magnetic shape memory alloys. here, we demonstrate that substitution of fe for ni can simultaneously enhance the mfirmt and mechanical properties of ni-mn-sn, which are advantageous for its applications. the austenite in ni44fe6mn39sn11 shows the typical ferromagnetic magnetization with the highest saturation magnetization of 69 emu/g at 223 k. the result show ... | 2017 | 28230152 |
| a comparative retrospective exploration of the profiles of patients in south africa diagnosed with epileptic and psychogenic non-epileptic seizures. | psychogenic non-epileptic seizures (pnes) have a high prevalence globally but the accurate diagnosis of this condition still remains a challenge. this is particularly the case in countries where there is scarce expertise and insufficient affordable medical facilities to which patients have access. the rate of pnes diagnosis in epilepsy units is typically within the range of 20 to 30%. in the context of developing countries, this rate tends to be higher and increases demand on the existing scarce ... | 2017 | 28222340 |
| nickel-salen supported paramagnetic nanoparticles for 6-his-target recombinant protein affinity purification. | in this research, a simple, efficient, inexpensive, rapid and high yield method for the purification of 6×histidine-tagged recombinant protein was developed. for this purpose, manganese ferrite magnetic nanoparticles (mnps) were synthesized through a co-precipitation method and then they were conveniently surface-modified with tetraethyl orthosilicate (teos) in order to prevent oxidation and form high density of hydroxyl groups. next, the salen ligand was prepared from condensation reaction of s ... | 2017 | 28215401 |
| utility of long-term video-eeg monitoring for children with staring. | staring spells are a common reason for referral to overnight epilepsy monitoring unit (emu) evaluation. however, inpatient emu admissions are expensive and time consuming. this study determined what percentage of those referred for staring had a confirmed epileptic seizure on long-term video-eeg monitoring (ltm) and developed a scoring system to help prioritize which patients should undergo this procedure. | 2017 | 28214777 |
| core-shell drug carrier from folate conjugated chitosan obtained from prawn shell for targeted doxorubicin delivery. | a multifunctional drug carrier with dual targeting (magnetic and folate-receptor) and ph sensitive core-shell hybrid nanomaterial has been developed to carry an anticancer drug doxorubicin.superparamagnetic iron oxide nanoparticles (ionps) were used as core of the carrier and cross-linked folate conjugated chitosan (fa-cs) was acted as shell in which doxorubicin was physically entrapped. transmission electron microscopy (tem) analysis confirmed the average particle size of ionps and fa-cs coated ... | 2017 | 28210967 |
| epilepsy monitoring - the patients' views: a qualitative study based on kolcaba's comfort theory. | the aim of this qualitative study was to determine which perception of personal comfort patients name in the context of their hospitalization in an austrian epilepsy monitoring unit (emu). | 2017 | 28202407 |
| 53bp1 contributes to igh locus chromatin topology during class switch recombination. | in b lymphocytes, ig class switch recombination (csr) is induced by activation-induced cytidine deaminase, which initiates a cascade of events leading to dna double-strand break formation in switch (s) regions. resolution of dna double-strand breaks proceeds through formation of s-s synaptic complexes. s-s synapsis is mediated by a chromatin loop that spans the c region domain of the igh locus. s-s junctions are joined via a nonhomologous end joining dna repair process. csr occurs via an intrach ... | 2017 | 28159901 |
| flexible heteroepitaxy of cofe2o4/muscovite bimorph with large magnetostriction. | a bimorph composed of ferrimagnetic cobalt ferrite (cofe2o4, cfo) and flexible muscovite was fabricated via van der waals epitaxy. the combination of x-ray diffraction and transmission electron microscopy was conducted to reveal the heteroepitaxy of the cfo/muscovite system. the robust magnetic behaviors against mechanical bending were characterized by hysteresis measurements and magnetic force microscopy, which maintain a saturation magnetization (ms) of ∼120-150 emu/cm(3) under different bendi ... | 2017 | 28155267 |
| distance magnetic nanoparticle detection using a magnetoelectric sensor for clinical interventions. | distance magnetic nanoparticle detections were investigated by using a magnetoelectric based magnetic sensor with a long type bilayer metglas/pzt laminate composite. in homogeneous magnetic fields, the sensor exhibits a sensitivity of 307.4 mv/oe, which is possible for a detection limit of 2.7 × 10(-7) emu. this sensor can detect an amount of 0.31 μg of the superparamagnetic fe3o4-chitosan fluid at 2 mm height above the sensor surface. to detect a spot with magnetic nanoparticles at a distance o ... | 2017 | 28147672 |
| mechanisms of spin-flipping and metal-insulator transition in nano-fe3o4. | fe3o4 is a half-metallic ferrimagnet with [formula: see text] k exhibiting metal-insulator transition (mit) at ∼120 k. in bulk form, the saturation magnetization is 0.6 tesla (∼471 emu cm(-3)). a recent experimental study has shown that the saturation magnetization of nano-fe3o4 thin films can achieve up to ∼760 emu cm(-3), attributed to spin-flipping of fe ions at tetrahedral sites assisted by oxygen vacancies (v o). such a system has shown to have higher mit temperature (∼150 k). the spin-fl ... | 2017 | 28140375 |
| fine tuning the performance of multiorbital radical conductors by substituent effects. | a critical feature of the electronic structure of oxobenzene-bridged bisdithiazolyl radicals 2 is the presence of a low-lying lumo which, in the solid state, improves charge transport by providing additional degrees of freedom for electron transfer. the magnitude of this multiorbital effect can be fine-tuned by variations in the π-electron releasing/accepting nature of the basal ligand. here we demonstrate that incorporation of a nitro group significantly stabilizes the lumo, and hence lowers ue ... | 2017 | 28117984 |
| perme intensive care unit mobility score and icu mobility scale: translation into portuguese and cross-cultural adaptation for use in brazil. | to translate the perme intensive care unit mobility score and the icu mobility scale (ims) into portuguese, creating versions that are cross-culturally adapted for use in brazil, and to determine the interobserver agreement and reliability for both versions. | 2017 | 28117473 |
| therapeutic efficacy of 4-1bb costimulation is abrogated by pd-1 blockade in a model of spontaneous b-cell lymphoma. | combinations of mabs that target various components of t-cell activation/inhibition may work synergistically to improve antitumor immunity against cancer. in this study, we investigated the therapeutic potential of combining an anticancer vaccination strategy with antibodies targeting an immune stimulatory (4-1bb) and immune inhibitory (pd-1) receptor, in a preclinical model of spontaneously arising c-myc-driven b-cell lymphoma. in eμ-myc transgenic mice, we reveal that 4-1bb agonistic mab treat ... | 2017 | 28115358 |
| one-step approach for the synthesis of cofe2o4@rgo core-shell nanocomposites as efficient adsorbent for removal of organic pollutants. | cofe2o4-reduced graphene oxide nanocomposites (cfg) have been successfully synthesized via one-step solvothermal method. the prepared cfg are characterized by x-ray diffraction, raman spectroscopy, fourier transform infrared spectroscopy, field emission scanning electron microscopy (fesem), vibrating sample magnetometer and so on. the fesem results show that cfg have uniform core-shell structure with an average diameter of about 75 nm and the thickness of the outer graphene shell is about 15-20 ... | 2017 | 28112667 |
| doping with graphitic nitrogen triggers ferromagnetism in graphene. | nitrogen doping opens possibilities for tailoring the electronic properties and band gap of graphene toward its applications, e.g., in spintronics and optoelectronics. one major obstacle is development of magnetically active n-doped graphene with spin-polarized conductive behavior. however, the effect of nitrogen on the magnetic properties of graphene has so far only been addressed theoretically, and triggering of magnetism through n-doping has not yet been proved experimentally, except for syst ... | 2017 | 28110530 |
| preparation of magnetic graphene oxide-ferrite nanocomposites for oxidative decomposition of remazol black b. | a solvothermal synthesis method was used to prepare graphene oxide (go) supported ferrite (mfe2o4, m=fe, co and ni) nanocomposites. subsequently, the application of mfe2o4 nanocomposites as photocatalyst for remazol black b (rbb) removal was investigated. the nanocomposites were characterized by x-ray powder diffraction (xrd), fourier transform infrared spectra (ft-ir), scanning electron microscopy (sem), energy-dispersive x-ray spectroscopy (eds), and vibrating sample magnetometer. it was shown ... | 2017 | 28109816 |
| correlation of cation distribution with the hyperfine and magnetic behaviour of ni0.3zn0.4co0.2cu0.1fe2o4 nanoparticles and their microwave absorption properties when encapsulated in multi-walled carbon nanotubes. | nanocrystalline samples of ni0.3zn0.4co0.2cu0.1fe2o4 (nzccf) are prepared by a simple co-precipitation method. to obtain nanoparticles of different sizes, the as prepared sample is annealed at 400, 600, 800 and 1000 °c. nanoparticles of the sample annealed at 600 °c are encapsulated in multi-walled carbon nanotubes (mwcnt). to confirm the crystallographic phase, x-ray diffraction (xrd) patterns are analyzed by the rietveld method and cation distribution in a- and b-sites is estimated from the an ... | 2017 | 28092634 |
| magnetic resonance study of bulk and thin film eutio3. | magnetic resonance spectra of eutio3 in both bulk and thin film form were taken at temperatures from 3-350 k and microwave frequencies from 9.2-9.8 and 34 ghz. in the paramagnetic phase, magnetic resonance spectra are determined by magnetic dipole and exchange interactions between eu(2+) spins. in the film, a large contribution arises from the demagnetization field. from detailed analysis of the linewidth and its temperature dependence, the parameters of spin-spin interactions were determined: t ... | 2017 | 28075333 |
| comparison of benzene and toluene photodegradation under visible light irradiation by ba-doped bifeo3 magnetic nanoparticles with fast sonochemical synthesis. | bi1-xbaxfeo3 (x = 0.02, 0.04 and 0.07) multiferroic materials with a diameter in the range of 30-40 nm were controllably synthesized by a facile ultrasonic method, with a very short reaction time of 5 min at a low temperature of 30 °c, and the resulting bifeo3 magnetic nanoparticles (bfo mnps) exhibited enhanced magnetic and photocatalytic performance. the substitution of ba(2+) ions for bi(3+) ions at the a-site of bfo mnps, even at only 2%, decreased their particle size and distorted the latti ... | 2017 | 28066846 |
| efficient removal of amoxicillin and paracetamol from aqueous solutions using magnetic activated carbon. | activated carbon (ac)/cofe2o4 nanocomposites, mac-1 and mac-2, were prepared by a simple pyrolytic method using a mixture of iron(iii)/cobalt(ii) benzoates and iron(iii)/cobalt(ii) oxalates, respectively, and were used as efficient adsorbents for the removal of amoxicillin (amx) and paracetamol (pct) of aqueous effluents. the synthesized nanocomposites were characterized by x-ray diffraction (xrd), fourier transform infrared spectroscopy (ft-ir), vibrating sample magnetometry (vsm), scanning ele ... | 2017 | 28064396 |
| integrated cellular and plasma proteomics of contrasting b-cell cancers reveals common, unique and systemic signatures. | approximately 800,000 leukemia and lymphoma cases are diagnosed worldwide each year. burkitt's lymphoma (bl) and chronic lymphocytic leukemia (cll) are examples of contrasting b-cell cancers; bl is a highly aggressive lymphoid tumor, frequently affecting children, whereas cll typically presents as an indolent, slow-progressing leukemia affecting the elderly. the b-cell-specific overexpression of the myc and tcl1 oncogenes in mice induce spontaneous malignancies modeling bl and cll, respectively. ... | 2017 | 28062796 |
| timing of first event in inpatient long-term video-eeg monitoring for diagnostic purposes. | long-term video-eeg monitoring (ltm) aims to record the habitual event and is a useful diagnostic tool for neurological paroxysmal clinical events. in our epilepsy monitoring unit (emu) setting, admissions are usually planned to last up to five days. we ascertained time taken for the recording of a first event and determined correlations between different clinical characteristics and timings. | 2017 | 28043065 |
| utility of a questionnaire tool (quaras) for localizing and lateralizing seizures in the epilepsy monitoring unit (emu). | an accurate description of the seizure semiology improves the recognition of the ictal onset zone and helps in hypothesizing the possible epileptogenic zone (ez). semiology based on a reliable description of seizures may be as good as investigative modalities, as has been shown by numerous studies. the main objective of this study was to apply a questionnaire-tool for auras and semiology (quaras) in refractory epilepsy cohort and compare its yield to that of standard history-taking. | 2017 | 28043024 |
| tiny adiabatic-demagnetization refrigerator for a commercial superconducting quantum interference device magnetometer. | a tiny adiabatic-demagnetization refrigerator (t-adr) has been developed for a commercial superconducting quantum interference device magnetometer [magnetic property measurement system (mpms) from quantum design]. the whole t-adr system is fit in a cylindrical space of diameter 8.5 mm and length 250 mm, and can be inserted into the narrow sample tube of mpms. a sorption pump is self-contained in t-adr, and hence no complex gas handling system is necessary. with the single crystalline gd3ga5o12 g ... | 2016 | 28040960 |
| limb patterning genes and heterochronic development of the emu wing bud. | the forelimb of the flightless emu is a vestigial structure, with greatly reduced wing elements and digit loss. to explore the molecular and cellular mechanisms associated with the evolution of vestigial wings and loss of flight in the emu, key limb patterning genes were examined in developing embryos. | 2016 | 28031782 |
| enhancement of ferromagnetism in nonmagnetic metal oxide nanoparticles by facet engineering. | ferromagnetism in semiconducting metal oxide nanoparticles has been intensively investigated due to their potential applications in spintronics, information storage, and biomedicine. ferromagnetism can be produced in nonmagnetic metal oxide nanoparticles by a variety of methods or factors, but the saturated magnetization is typically of the order of 10(-4) emu g(-1) and too small to be useful in practice. in this work, it is demonstrated theoretically and experimentally that stronger ferromagnet ... | 2017 | 27957803 |
| bmi-1 mediates estrogen-deficiency-induced bone loss by inhibiting reactive oxygen species accumulation and t cell activation. | previous studies have shown that estrogen regulates bone homeostasis through regulatory effects on oxidative stress. however, it is unclear how estrogen deficiency triggers reactive oxygen species (ros) accumulation. recent studies provide evidence that the b lymphoma mo-mlv insertion region 1 (bmi-1) plays a critical role in protection against oxidative stress and that this gene is directly regulated by estrogen via estrogen receptor (er) at the transcriptional level. in this study, ovariectomi ... | 2016 | 27943387 |
| effect of the number of methyl groups on the cation affinity of oxygen, nitrogen, and phosphorus sites of lewis bases. | the effect of number of ch3 groups (n) on the cation (h(+), li(+), na(+), al(+), ch3(+)) affinity, polarizability, and dipole moment of 14 simple molecules was investigated. linear correlations were observed between the polarizabilities and the number of methyl groups. the variations of the cation affinities and dipole moments with the number of methyl groups (n) were not linear, and a quadratic function was proposed for obtaining a good fit of the experimental data. also, because the proton aff ... | 2016 | 27934334 |
| preparation of hollow core/shell fe3o4@graphene oxide composites as magnetic targeting drug nanocarriers. | a main challenge for anticancer drugs is that the drugs can not arrive the cancer tissue at right time. in this work, a magnetic targeting nanoparticle based on hollow fe3o4/graphene oxide (fe3o4/go) was developed as a potential tumor targeting drug carriers. the morphology results showed the fe3o4 nanoparticles were uniformly wrapped by graphene oxide. after coating with graphene oxide, the fe3o4/go showed a higher saturation magnetization of 71.47 emu g(-1) as compared to neat fe3o4 nanopartic ... | 2017 | 27931160 |
| data on melanin production in b16f1 melanoma cells in the presence of emu oil. | here, we present data on the effects of emu oil, obtained from emu (dromaius novaehollandiae) fat deposits, on melanogenesis in b16f1 murine melanoma cells. the cells were cultured in media containing different concentrations of emu oil, and the melanin content of these cells was measured using a microplate reader. next, melanin content was measured for cells cultured with α-melanocyte-stimulating hormone. this article reports the different melanin contents as μg melanin/mg cellular protein, by ... | 2016 | 27924292 |
| silica-coated magnetite nanoparticles core-shell spheres (fe3o4@sio2) for natural organic matter removal. | in this work, the magnetite (fe3o4) nanoparticles (mnps) and silica-coated magnetite nanoparticles (smnps) were synthesized as adsorbents for removing humic acid (ha) from water resources. | 2016 | 27924220 |
| synthesis, characterization, and study of in vitro cytotoxicity of zno-fe3o4 magnetic composite nanoparticles in human breast cancer cell line (mda-mb-231) and mouse fibroblast (nih 3t3). | novel magnetic composite nanoparticles (mcps) were successfully synthesized by ex situ conjugation of synthesized zno nanoparticles (zno nps) and fe3o4 nps using trisodium citrate as linker with an aim to retain key properties of both nps viz. inherent selectivity towards cancerous cell and superparamagnetic nature, respectively, on a single system. successful characterization of synthesized nanoparticles was done by xrd, tem, ftir, and vsm analyses. vsm analysis showed similar magnetic profile ... | 2016 | 27914092 |
| phosphate reclaim from simulated and real eutrophic water by magnetic biochar derived from water hyacinth. | in this study, the efficiency and mechanism of aqueous phosphate removal by magnetic biochar derived from water hyacinth (mw) were investigated. the mw pyrolyzed at 450 °c (mw450) exhibited the most prominent phosphate sorption capacity, which was estimated to be 5.07 mg g(-1) based on langmuir-freundlich model. at an initial phosphorus (p) concentration of 1 mg l(-1), >90% p removal was achieved over ph 3-9, but the efficiency decreased sharply at ph > 10. the presence of arsenate and carbonate ... | 2017 | 27912132 |
| the bruton tyrosine kinase (btk) inhibitor acalabrutinib demonstrates potent on-target effects and efficacy in two mouse models of chronic lymphocytic leukemia. | purpose: acalabrutinib (acp-196) is a novel, potent, and highly selective bruton tyrosine kinase (btk) inhibitor, which binds covalently to cys481 in the atp-binding pocket of btk. we sought to evaluate the antitumor effects of acalabrutinib treatment in two established mouse models of chronic lymphocytic leukemia (cll).experimental design: two distinct mouse models were used, the tcl1 adoptive transfer model where leukemic cells from eμ-tcl1 transgenic mice are transplanted into c57bl/6 mice, a ... | 2016 | 27903679 |
| early generated b1 b cells with restricted bcrs become chronic lymphocytic leukemia with continued c-myc and low bmf expression. | in mice, generation of autoreactive cd5(+) b cells occurs as a consequence of bcr signaling induced by (self)-ligand exposure from fetal/neonatal b-1 b cell development. a fraction of these cells self-renew and persist as a minor b1 b cell subset throughout life. here, we show that transfer of early generated b1 b cells from eμ-tcl1 transgenic mice resulted in chronic lymphocytic leukemia (cll) with a biased repertoire, including stereotyped bcrs. thus, b1 b cells bearing restricted bcrs can bec ... | 2016 | 27899442 |
| determination of trace bisphenol a in environmental water by high-performance liquid chromatography using magnetic reduced graphene oxide based solid-phase extraction coupled with dispersive liquid-liquid microextraction. | bisphenol a (bpa), an endocrine-disrupting chemical, has received much attention from researchers and the general public. in this paper, a novel method of determining bpa at trace levels was developed, using magnetic reduced graphene oxide (rgo-fe3o4)-based solid-phase extraction coupled with dispersive liquid-liquid microextraction (dllme), followed by high-performance liquid chromatographic determination. the rgo-fe3o4 was prepared and then characterized by fourier transform infrared spectrosc ... | 2017 | 27888310 |
| histone deacetylase 1 plays a predominant pro-oncogenic role in eμ-myc driven b cell lymphoma. | the two histone deacetylases (hdacs), hdac1 and hdac2, are erasers of acetylation marks on histone tails, and are important regulators of gene expression that were shown to play important roles in hematological malignancies. however, several recent studies reported opposing tumor-suppressive or tumor-promoting roles for hdac1 and hdac2. here, we investigated the functional role of hdac1 and hdac2 using the eμ-myc mouse model of b cell lymphoma. we demonstrate that hdac1 and hdac2 have a pro-onco ... | 2016 | 27886239 |
| estimates of radiation doses to the skin for people camped at wallatinna during the uk totem 1 atomic weapons test. | a group of aboriginal people was camped at wallatinna in south australia, ~170 km downwind from emu field, where an atomic test (the totem 1 test) was carried out at 07.00 on 15 october 1953 local time (21.30 on 14 october 1953 gmt (greenwich mean time)). they left the camp ~24 hours later. these people stated that a phenomenon that has become known as a 'black mist' rolled through their camp site ~5 hours after detonation and that some of them subsequently became sick, displaying skin reddening ... | 2016 | 27881792 |
| lanthanide sorbent based on magnetite nanoparticles functionalized with organophosphorus extractants. | in this work, an adsorbent was prepared based on the attachment of organophosphorus acid extractants, namely, d2ehpa, cyanex 272, and cyanex 301, to the surface of superparamagnetic magnetite (fe3o4) nanoparticles. the synthesized nanoparticles were coated with oleic acid, first by a chemisorption mechanism and later by the respective extractant via physical adsorption. the obtained core-shell functionalized magnetite nanoparticle composites were characterized by dynamic light scattering, scanni ... | 2015 | 27877811 |
| synthesis, characterization and antibacterial activity of superparamagnetic nanoparticles modified with glycol chitosan. | iron oxide nanoparticles (ionps) were synthesized by coprecipitation of iron salts in alkali media followed by coating with glycol chitosan (gc-coated ionps). both bare and gc-coated ionps were subsequently characterized and evaluated for their antibacterial activity. comparison of fourier transform infrared spectra and thermogravimetric data of bare and gc-coated ionps confirmed the presence of gc coating on ionps. magnetization curves showed that both bare and gc-coated ionps are superparamagn ... | 2012 | 27877469 |
| dependence of phase configurations, microstructures and magnetic properties of iron-nickel (fe-ni) alloy nanoribbons on deoxidization temperature in hydrogen. | iron-nickel (fe-ni) alloy nanoribbons were reported for the first time by deoxidizing nife2o4 nanoribbons, which were synthesized through a handy route of electrospinning followed by air-annealing at 450 °c, in hydrogen (h2) at different temperatures. it was demonstrated that the phase configurations, microstructures and magnetic properties of the as-deoxidized samples closely depended upon the deoxidization temperature. the spinel nife2o4 ferrite of the precursor nanoribbons were firstly deoxid ... | 2016 | 27876878 |
| pi3kδ inhibition elicits anti-leukemic effects through bim-dependent apoptosis. | pi3kδ plays pivotal roles in the maintenance, proliferation and survival of malignant b-lymphocytes. although not curative, pi3kδ inhibitors (pi3kδi) demonstrate impressive clinical efficacy and, alongside other signaling inhibitors, are revolutionizing the treatment of hematological malignancies. however, only limited in vivo data are available regarding their mechanism of action. with the rising number of novel treatments, the challenge is to identify combinations that deliver curative regimes ... | 2016 | 27843137 |
| co-expression of sialic acid receptors compatible with avian and human influenza virus binding in emus (dromaius novaehollandiae). | influenza a viruses (iavs) continue to threaten animal and human health with constant emergence of novel variants. while aquatic birds are a major reservoir of most iavs, the role of other terrestrial birds in the evolution of iavs is becoming increasingly evident. since 2006, several reports of iav isolations from emus have surfaced and avian influenza infection of emus can lead to the selection of mammalian like pb2-e627k and pb2-d701n mutants. however, the potential of emus to be co-infected ... | 2017 | 27816637 |
| detecting markers of therapy-induced senescence in cancer cells. | therapy-induced senescence (tis), a lasting chemotherapy-evoked proliferative arrest of tumor cells, has gained increasing attention by cancer researchers because of its' profound biological implications, and by clinical oncologists due to its potential contribution to the long-term outcome of cancer patients post-treatment. although both apoptosis and senescence represent therapy-inducible, ultimate cell-cycle exit programs, mediated via dna damage response signaling, apoptotic cell death as th ... | 2017 | 27812866 |