Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| antiprotozoal activity of extracts of elaeodendron trichotomum (celastraceae). | chagas disease, amebiasis, giardiasis and trichomoniasis represent a serious health problem in latin america. the drugs employed to treat these illnesses produce important side effects and resistant strains have appeared. the present study was aimed to evaluate the antiprotozoal activity of leaves, stem bark and root bark of elaeodendron trichotomum, a celastraceus, that is used in mexico as an anti-infective in febrile-type diseases. | 2016 | 28852732 |
| prevalence of intestinal parasitic infection among primary school children in southern iran. | a cross-sectional study was carried out to determine the prevalence of intestinal parasites in primary school children in bandar abbas, southern iran during january to march 2016. single stool samples were collected from 1465 participants by clean stool cup. the questionnaire was prepared on the basis of demographic characteristics. the diagnosis was made on the basis of the direct wet mount, formalin-ether concentration, and ziehl-neelsen and trichrome stained slides. out of the 1465 school chi ... | 2017 | 28848255 |
| an overview of parasitic infections of the gastro-intestinal tract in developed countries affecting immunocompromised individuals. | in both developed and developing countries, parasitic infections continue to be a frequent cause of mortality and morbidity. due to the globalization of the world, doctors must be fully prepared to deal with a plethora of parasitic infections. more commonly the gastrointestinal (gi) tract is infected and in developed countries protozoans are more likely to be the cause of infection compared to helminths. these gi protozoa are progressively becoming recognized as important pathogens in patients t ... | 2017 | 28848249 |
| intestinal parasitic infections: current prevalence and risk factors among schoolchildren in capital area of the republic of marshall islands. | intestinal parasitic infections (ipis) among schoolchildren in republic of marshall islands (rmi) largely remains unknown, thus investigation on ipis status to establish the baseline data is urgently needed. this cross-sectional study intended to investigate the current ipis status and associated risk factors among schoolchildren at capital of rmi. single stool sample from 400 schoolchildren (207 boys and 193 girls) aged 9.73±2.50 yrs old was examined by employing merthiolate-iodine-formaldehyde ... | 2017 | 28847672 |
| evaluation of primitive ground water supplies as a risk factor for the development of major waterborne zoonosis in egyptian children living in rural areas. | endemic waterborne zoonosis frequently occurs in both developed and less developed countries. thus, bio-surveillance of waterborne zoonosis is a "necessity" for the implementation of effective preventive public health measures in egyptian rural areas. the primitive individual water supplies created by the rural agriculture population, primarily from ground water, usually maximize the customers' exposure to impurity pathogens via diffused humans and animal excreta or wastages. the current study a ... | 2017 | 28843417 |
| survey of the occurrence and human infective potential of giardia duodenalis and cryptosporidium spp. in wastewater and different surface water sources of western romania. | from the group of parasitic protozoa, giardia and cryptosporidium are the most common pathogens spread in surface water sources, representing a continuous threat to public health and water authorities. the aim of this survey was to assess the occurrence and human infective potential of these pathogens in treated wastewaters and different surface water sources. a total of 76 western romanian water bodies in four counties (arad, bihor, caraș-severin and timiș) were investigated, including the effl ... | 2017 | 28832257 |
| the intersection of immune responses, microbiota, and pathogenesis in giardiasis. | giardia lamblia is one of the most common infectious protozoans in the world. giardia rarely causes severe life-threatening diarrhea, and may even have a slight protective effect in this regard, but it is a major contributor to malnutrition and growth faltering in children in the developing world. giardia infection also appears to be a significant risk factor for postinfectious irritable bowel and chronic fatigue syndromes. in this review we highlight recent work focused on the impact of giardia ... | 2017 | 28830665 |
| molecular analysis of the enteric protozoa associated with acute diarrhea in hospitalized children. | pediatric diarrhea is a common cause of death among children under 5 years of age. in the current study, we investigated the frequency of intestinal parasites among 580 pediatric patients with chronic diarrhea. parasitic protozoa (all species combined) were detected by molecular tools in 22.9% of the children and the most common parasite was cryptosporidium spp. (15.1%). blastocystis hominis was detected in 4.7%, dientamoeba fragilis in 4%, giardia duodenalis in 1.7%, and entamoeba histolytica i ... | 2017 | 28824878 |
| cysteine protease-dependent mucus disruptions and differential mucin gene expression in giardia duodenalis infection. | the intestinal mucus layer provides a critical host defense against pathogen exposure and epithelial injury, and yet little is known of how enteropathogens may circumvent this physiological barrier. giardia duodenalis is a small intestinal parasite responsible for diarrheal disease and chronic post-infectious illness. this study reveals a complex interaction at the surface of epithelial cells, between g. duodenalis and the intestinal mucus layer. here, we reveal mechanisms whereby g. duodenalis ... | 2017 | 28823873 |
| variation in basal body localisation and targeting of trypanosome rp2 and for20 proteins. | tof-lish-pll motifs define fop family proteins; some members are involved in flagellum assembly. the critical role of fop family protein for20 is poorly understood. here, we report relative localisations of the four fop family proteins in parasitic trypanosoma brucei: tbrp2, tbofd1 and tbfop/fop1-like are mature basal body proteins whereas tbfor20 is present on pro- and mature basal bodies - on the latter it localises distal to tbrp2. we discuss how the data, together with published work for ano ... | 2017 | 28822909 |
| larrea tridentata: a novel source for anti-parasitic agents active against entamoeba histolytica, giardia lamblia and naegleria fowleri. | protozoan parasites infect and kill millions of people worldwide every year, particularly in developing countries where access to clean fresh water is limited. among the most common are intestinal parasites, including giardia lamblia and entamoeba histolytica. these parasites wreak havoc on the epithelium lining the small intestines (g. lamblia) and colon (e. histolytica) causing giardiasis and amebiasis, respectively. in addition, there are less common but far more deadly pathogens such as naeg ... | 2017 | 28793307 |
| environmental aspects related to tuberculosis and intestinal parasites in a low-income community of the brazilian amazon. | we carried out a cross-sectional study from january to december 2015 on 1,425 inhabitants from a floating population in the brazilian amazon (murinin district, pará state) to describe the population-based prevalence of tuberculosis (tb) from 2011 to 2014, recent tb contacts (rcts) latently infected with mycobacterium tuberculosis (ltbi) , the coverage of the local health network, socio-environmental factors, and frequency of intestinal parasitic infection (ipi). we found that the sanitary struct ... | 2017 | 28793025 |
| socioenvironmental conditions and intestinal parasitic infections in brazilian urban slums: a cross-sectional study. | a cross-sectional study covering an agglomeration of urban slums was conducted between 2015 and 2016 using participants observation, a socioeconomic survey, and the spontaneous sedimentation method with three slides per sample to analyze fresh stool specimens ( n =595) searching for intestinal parasites. | 2017 | 28793024 |
| evaluation of the bd max enteric parasite panel for the detection of cryptosporidium parvum/hominis, giardia duodenalis and entamoeba histolytica. | conventional laboratory detection methods for gastrointestinal parasites are time consuming, require considerable technical expertise and may suffer from poor analytical sensitivity. this study sought to evaluate the automated bd max enteric parasite panel (epp) for the detection of cryptosporidium parvum/hominis, entamoeba histolytica and giardia duodenalis.methodolgy. a total of 104 known positive samples (43 cryptosporidium parvum/hominis and 61 g. duodenalis), 15 simulated samples (e. histol ... | 2017 | 28792380 |
| a method for incorporating a time-dose-response model into a giardia lamblia outbreak. | experimental time-to-infection data is a useful, but often underutilized, material for examining the mechanics of in vivo pathogen growth. in this paper, the authors attempt to incorporate a time-dose-response (tdr) equation into a model which predicts the number of ill persons per day in a giardia lamblia epidemic using data collected from a pittsfield, massachusetts outbreak. to this end, dose-response and tdr models were generated for giardia exposure to beaver and human volunteers, and a max ... | 2017 | 28771146 |
| insights into the giardia intestinalis enolase and human plasminogen interaction. | giardia intestinalis is an intestinal parasite that causes diarrhea in humans and animals worldwide. the enolase of g. intestinalis (gieno) participates in its glycolysis pathway and is abundantly expressed in the parasite cytosol; however, its localization on the surface of trophozoites and cysts has been demonstrated. enolases from bacteria and parasites can have different functions and are considered moonlighting proteins, for example, as a cell surface plasminogen receptor. in relation to gi ... | 2017 | 28770921 |
| detection and multilocus genotyping of giardia duodenalis in dogs in sichuan province, china. | giardia duodenalis (also known as g. intestinalis) is a flagellated protozoan that parasitizes the small intestine and is a common causal agent of zoonotic infections in humans and animals. to assess the genetic diversity and zoonotic transmission potential of g. duodenalis in stray dogs, 159 fecal specimens were collected from dogs in chengdu, yaan, and leshan in sichuan province, china. of the 159 fecal samples from stray dogs, 18 (11.3%) were g. duodenalis-positive based on nested pcr amplifi ... | 2017 | 28770713 |
| genetic variation of giardia lamblia isolates from food-handlers in kashan, central iran. | based on genotyping study of human isolates of giardia lamblia; humans are mainly infected by two assemblages a and b. the present study was carried out to determine the sub-assemblages of g. lamblia isolated from food handlers referred to kashan health centers, central iran, 2015. | 2017 | 28761464 |
| immunologic detection of giardia duodenalis in a specific pathogen-free captive olive baboon ( papio cynocephalus anubis) colony. | several commercial giardia immunoassays were evaluated in baboons for sensitivity and specificity as well as ease of use in a large specific pathogen-free (spf) colony. an additional objective was to identify the assemblage(s) of giardia duodenalis present in this baboon colony. a direct immunofluorescent antibody test (ifat) was used as the reference test. tests evaluated were a patient-side rapid test for dogs and cats, a human rapid test, and a well-plate elisa designed for use with humans. t ... | 2017 | 28754076 |
| cross-modulation of pathogen-specific pathways enhances malnutrition during enteric co-infection with giardia lamblia and enteroaggregative escherichia coli. | diverse enteropathogen exposures associate with childhood malnutrition. to elucidate mechanistic pathways whereby enteric microbes interact during malnutrition, we used protein deficiency in mice to develop a new model of co-enteropathogen enteropathy. focusing on common enteropathogens in malnourished children, giardia lamblia and enteroaggregative escherichia coli (eaec), we provide new insights into intersecting pathogen-specific mechanisms that enhance malnutrition. we show for the first tim ... | 2017 | 28750066 |
| use of serologic responses against enteropathogens to assess the impact of a point-of-use water filter: a randomized controlled trial in western province, rwanda. | diarrhea is a leading contributor to childhood morbidity and mortality in sub-saharan africa. given the challenge of blinding most water, sanitation, and hygiene (wash) interventions, diarrheal disease outcome measures in wash intervention trials are subject to potential bias and misclassification. using the platform of a cluster-randomized controlled trial of a household-based drinking water filter in western province, rwanda, we assessed the impact of the drinking water filter on enteric seroc ... | 2017 | 28749764 |
| cryptosporidium and giardia infections in children: a review. | diarrheal disease remains the second leading cause of mortality in children in developing countries. cryptosporidium is a leading cause and its importance stands to increase as rotavirus vaccine becomes used around the world. cryptosporidium is particularly problematic in children younger than 2 years old and in the immunocompromised. giardia lamblia is a common intestinal protozoan that is associated with diarrhea and, perhaps, growth faltering in impoverished settings. this review establishes ... | 2017 | 28734513 |
| cryptosporidium infection in children with cancer undergoing chemotherapy: how important is the prevention of opportunistic parasitic infections in patients with malignancies? | cryptosporidiosis is a relatively uncommon disease in healthy individuals but could be potentially worrisome in immunocompromised patients. this study aimed to evaluate cryptosporidium infection in children with cancer undergoing chemotherapy. a case-control study was conducted in 132 children with cancer undergoing chemotherapy and 132 non-cancer controls. the modified ziehl-neelsen (mzn) staining and polymerase chain reaction methods were used for the detection of cryptosporidium parasite. all ... | 2017 | 28730516 |
| comparison of cytokine responses in ecuadorian children infected with giardia, ascaris, or both parasites. | abstractmore than 2 billion people are infected with parasites globally, and the majority have coinfections. intestinal protozoa and helminths induce polarizing cd4(+) t-helper cell 1 (th1) mediated cytokine responses within the host. such immune polarization may inhibit the ability of the host to mount an adequate immune response for pathogen clearance to concurrent pathogens. the current study evaluated the plasma cytokine profile in ascaris and giardia coinfected children compared with giardi ... | 2017 | 28719267 |
| stool antigen immunodetection for diagnosis of giardia duodenalis infection in human subjects with hiv and cancer. | human infection with the protozoan parasite giardia duodenalis is one the most common parasitic diseases worldwide. higher incidence rates of giardiasis have been reported from human subjects with multiple debilitating chronic conditions, including hypogammaglobulinemia and common variable immunodeficiency (cvid). in the current study, stool specimens were collected from 199 individuals diagnosed with hiv or cancer and immunocompetent subjects. the sensitivity of microscopy-based detection on fr ... | 2017 | 28716658 |
| prevalence of enteric infections among hospitalized patients in two referral hospitals in ghana. | diarrhea is an important cause of morbidity and mortality worldwide. in africa and ghana in particular, it is estimated to contribute directly to 19 and 25% of pediatric mortality among children under 5 years, respectively. | 2017 | 28716138 |
| intestinal parasitic infections: current status and associated risk factors among school aged children in an archetypal african urban slum in nigeria. | intestinal parasitic infections (ipis) among school aged children (sac) in nigeria remains endemic, hence the need for regular surveillance to attract the attention of policy makers. this cross-sectional study investigated the current prevalence and factors associated with intestinal parasitic infections among school aged children in an urban slum of lagos city, nigeria. | 2017 | 28711437 |
| detection of zoonotic and livestock-specific assemblages of giardia duodenalis in free-living wild lizards. | giardia duodenalis is a zoonotic parasite that infects the gut of a wide range of vertebrates, including numerous wildlife species. however, little is known about this protozoan parasite in reptiles. fecal samples from 31 wild lizards were collected in galicia (northwest spain) and screened for the presence of giardia by pcr amplification and sequencing of the its1-5.8s-its2 region in the ribosomal unit. this allowed detection of the parasite in 5 samples (16.1%), and enabled identification of g ... | 2017 | 28699999 |
| reduced efficacy of albendazole against ascaris lumbricoides in rwandan schoolchildren. | control of human soil-transmitted helminths (sths) relies on preventive chemotherapy of schoolchildren applying the benzimidazoles (bz) albendazole or mebendazole. anthelmintic resistance (ar) is a common problem in nematodes of veterinary importance but for human sths, information on drug efficacy is limited and routine monitoring is rarely implemented. herein, the efficacy of single dose albendazole (400 mg) was evaluated in 12 schools in the huye district of rwanda where ascaris is the predom ... | 2017 | 28697451 |
| endoplasmic reticulum is the sorting core facility in the golgi-lacking protozoan giardia lamblia. | our understanding of protein and lipid trafficking in eukaryotic cells has been challenged by the finding of different forms of compartmentalization and cargo processing in protozoan parasites. here, we show that, in the absence of a golgi compartment in giardia, proteins destined for secretion are directly sorted and packaged at specialized er regions enriched in copii coatomer complexes and ceramide. we also demonstrated that er-resident proteins are retained at the er by the action of a kdel ... | 2017 | 28696565 |
| sorting without a golgi complex. | the endoplasmic reticulum-golgi-target organelle route is one of the most studied events and has fascinated researchers for years. however, the conservative mechanism of protein sorting and delivery is now being challenged by the finding of unconventional pathways driving protein sorting and transport. protozoa parasites are being rediscovered as good models for analyzing alternative targeting pathways, associated with their ability to adapt to diverse environments and hosts. here, we have gathe ... | 2017 | 28696551 |
| morphological and physiological characteristics of a virulent and zoonotic assemblage a giardia duodenalis canine strain. | giardiasis is an intestinal parasitosis that affects millions of people worldwide and is considered a zoonotic disease. frequently in contact with humans, dogs are the main host involved in this zoonotic transmission. here, we compared some aspects of giardia duodenalis biology between two strains: a recently isolated dog strain (bhfc1) and a human reference strain (portland-1). growth curve analysis revealed that bhfc1 trophozoites multiply faster than the human isolate portland-1 in axenic cul ... | 2017 | 28689000 |
| myosin-independent cytokinesis in giardia utilizes flagella to coordinate force generation and direct membrane trafficking. | devoid of all known canonical actin-binding proteins, the prevalent parasite giardia lamblia uses an alternative mechanism for cytokinesis. unique aspects of this mechanism can potentially be leveraged for therapeutic development. here, live-cell imaging methods were developed for giardia to establish division kinetics and the core division machinery. surprisingly, giardia cytokinesis occurred with a median time that is ∼60 times faster than mammalian cells. in contrast to cells that use a contr ... | 2017 | 28679631 |
| acute acalculous cholecystitis caused by giardia lamblia. | we report a case of a 70-year-old man with acute acalculous cholecystitis caused by giardia lamblia. contrast-enhanced computed tomography (ct) showed distention of the gallbladder due to a pericholecystic abscess without gallstones. magnetic resonance cholangiopancreatography and drip infusion cholecystocholangiography-ct demonstrated a stricture of the hilar bile duct and cystic duct obstruction. we conducted transpapillary bile duct brush cytology and a biopsy of the hilar bile duct stricture ... | 2017 | 28674353 |
| recreational waterborne illnesses: recognition, treatment, and prevention. | illness after recreational water activities can be caused by a variety of agents, including bacteria, viruses, parasites, algae, and even chlorine gas. these illnesses are more common in summer. waterborne illnesses are underreported because most recreational activity occurs in unsupervised venues or on private property, and participants tend to disperse before illness occurs. symptoms of waterborne illness are primarily gastrointestinal, but upper respiratory and skin manifestations also occur. ... | 2017 | 28671392 |
| new multilocus genotypes of giardia lamblia human isolates. | giardia lamblia is considered a species complex, whose members show little differences in their morphology, but have remarkable genetic variability. the aim of this study was to identify inter- and intra-assemblage genetic variation in g. lamblia among patients in rio de janeiro. the parasitological study was performed on faeces, and dna was extracted from the samples which tested positive for g. lamblia. the genetic assemblages and subtypes were determined via multilocus sequence typing (mlst) ... | 2017 | 28669825 |
| expression and secretion of the giardia duodenalis variant surface protein 9b10a by transfected trophozoites causes damage to epithelial cell monolayers mediated by protease activity. | giardia duodenalis is the protozoan parasite responsible for most cases of parasitic diarrhea worldwide. the pathogenic mechanisms of giardiasis have not yet been fully characterized. in this context parasite's excretory/secretory products have been related to the damage induced by the parasite on enterocytes. among these is the variable surface proteins (vsps) family involved in antigenic variation and in the induction of protective response. in proteomic analyses carried out to identify the pr ... | 2017 | 28668253 |
| giardia colonizes and encysts in high-density foci in the murine small intestine. | giardia lamblia is a highly prevalent yet understudied protistan parasite causing significant diarrheal disease worldwide. hosts ingest giardia cysts from contaminated sources. in the gastrointestinal tract, cysts excyst to become motile trophozoites, colonizing and attaching to the gut epithelium. trophozoites later differentiate into infectious cysts that are excreted and contaminate the environment. due to the limited accessibility of the gut, the temporospatial dynamics of giardiasis in the ... | 2017 | 28656177 |
| profile of intestinal parasitosis among school-aged children in kiliba (eastern dr congo). | this study of feces sought to determine the prevalence of human intestinal parasites in the kiliba area of the eastern dr congo. feces of 602 school children aged from 9 to 20 years were collected from april to june 2014 and examined. direct analyses were supplemented with the kato and ritchie methods. the global prevalence of intestinal parasitosis in school-aged children in the kiliba area was 91.4 % [95 % ci: 87.6-94.3%]. the frequency of helminthiasis was high at 73.8 % (95 % ci: 68.4-78.6%) ... | 2017 | 28655684 |
| intestinal parasites in stool samples and perianal swabs examined by the voivodeship sanitary-epidemiological station in bydgoszcz between 2000-2014 | epidemiological conditions are changing due to the modifications in human behavior and environment. parasitic diseases are most often caused by intestinal parasites. the frequency of echinococcus multilocularis and tropical diseases increases in poland. | 2017 | 28654741 |
| giardia duodenalis and cryptosporidium spp. as contaminant protozoa of the main rivers of western romania: genetic characterization and public health potential of the isolates. | the objective of this study was to establish the prevalence, contamination level, and public health significance of giardia duodenalis and cryptosporidium spp. in the primary rivers of western romania. a total of 53 sampling points in the 24 most important western romanian rivers in four counties (arad, bihor, caraș-severin, and timiș) were investigated from march to september 2016. surface water samples were collected by microfiber filtration. cryptosporidium and giardia (oo)cysts were isolated ... | 2017 | 28653194 |
| detection and prevalence of protozoan parasites in ready-to-eat packaged salads on sale in italy. | to investigate the prevalence of protozoan contamination by giardia duodenalis, cryptosporidium spp., toxoplasma gondii and cyclospora cayetanensis, in 'ready to eat' (rte) salads on sale in italy, 648 packages were purchased from industrial and local brands. nine individual packages from each brand were collected per month, pooled and subjected to microscopy and molecular analyses. microscopic examination of 864 slides detected cryptosporidium spp. but also blastocystis hominis and dientamoeba ... | 2017 | 28648295 |
| synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-nsaid chimeras displaying broad antiprotozoal spectrum. | we designed and synthesized five new 5-nitrothiazole-nsaid chimeras as analogues of nitazoxanide, using a dcc-activated amidation. compounds 1-5 were tested in vitro against a panel of five protozoa: 2 amitochondriates (giardia intestinalis, trichomonas vaginalis) and 3 kinetoplastids (leishmania mexicana, leishmania amazonensis and trypanosoma cruzi). all chimeras showed broad spectrum and potent antiprotozoal activities, with ic50 values ranging from the low micromolar to nanomolar order. comp ... | 2017 | 28645659 |
| pcr-based verification of positive rapid diagnostic tests for intestinal protozoa infections with variable test band intensity. | stool-based rapid diagnostic tests (rdts) for pathogenic intestinal protozoa (e.g. cryptosporidium spp. and giardia intestinalis) allow for prompt diagnosis and treatment in resource-constrained settings. such rdts can improve individual patient management and facilitate population-based screening programmes in areas without microbiological laboratories for confirmatory testing. however, rdts are difficult to interpret in case of 'trace' results with faint test band intensities and little is kno ... | 2017 | 28634143 |
| multiplex pcr gastro-intestinal panels for the management of traveller's diarrhea : are they accurate and useful? | until recently, the search for enteropathogens causing travellers' diarrhea was based on stool culture (campylobacter spp., salmonella spp. and shigella spp.), direct microscopy with (cryptosporidium spp.) or without specific staining (giardia lamblia, entamoeba histolytica) or specific antigen detection (giardia lamblia, entamoeba histolytica). molecular analyses are progressively replacing traditional diagnostic methods but their clinical usefulness remains to be better defined. this article a ... | 2017 | 28627855 |
| nitroimidazole-refractory giardiasis; a growing problem requiring rational solutions. | giardia intestinalis is microaerophillic diarrhoea-causing protozoan common in countries with suboptimal sanitation. standard treatment is with nitroimidazoles but a growing number of refractory cases are being reported. treatment failure has become increasingly prevalent in travellers who contract giardiasis in asia. clinicians are increasingly falling back on second line and less well known drugs to treat giardiasis. | 2017 | 28624613 |
| giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 and attenuates attaching and effacing bacteria-induced intestinal disease. | our understanding of polymicrobial gastrointestinal infections and their effects on host biology remains incompletely understood. giardia duodenalis is an ubiquitous intestinal protozoan parasite infecting animals and humans. concomitant infections with giardia and other gastrointestinal pathogens commonly occur. in countries with poor sanitation, giardia infection has been associated with decreased incidence of diarrheal disease and fever, and reduced serum inflammatory markers release, via mec ... | 2017 | 28622393 |
| molecular diversity and frequency of the diarrheagenic enteric protozoan giardia duodenalis and cryptosporidium spp. in a hospital setting in northern spain. | human giardiosis and cryptosporidiosis are caused by the enteric protozoan parasites giardia duodenalis and cryptosporidium spp. both pathogens are major contributors to the global burden of diarrhoeal disease, affecting primarily children and immunodebilitated individuals in resource-poor settings. giardiosis and cryptosporidiosis also represent an important, often underestimate, public health threat in developed countries. in spain only limited information is currently available on the epidemi ... | 2017 | 28617836 |
| intestinal parasitic infestation among paediatric diarrhoea patients attending hospitals in port blair, andaman and nicobar islands. | acute childhood diarrhoea remains one of the leading causes of childhood morbidity and mortality in developing countries. the present study was conducted to estimate the prevalence of various intestinal parasitic infestation among children aged 5 years and less suffering from acute diarrhoea disease attending hospitals in andaman islands. during the period from january 2012 to december 2013, a total of 675 acute diarrhoea patients were included in the study. among these samples, 476 (70.5, 95 % ... | 2017 | 28615884 |
| prevalence of giardiaduodenalis among children from a central region of cuba: molecular characterization and associated risk factors. | giardia duodenalis is one of the most frequent intestinal parasitic infections in children worldwide. to date, eight main assemblages of g. duodenalis have been described, but only a and b genetic groups are known to infect humans. a cross-sectional study was conducted to determine the prevalence and risk factors of giardia duodenalis infection in 417 preschool children from the fomento municipality in the central region of cuba between january and june 2013. the overall prevalence of giardia in ... | 2017 | 28615850 |
| first detection and genotyping of giardia intestinalis in stool samples collected from children in ghazni province, eastern afghanistan and evaluation of the pcr assay in formalin-fixed specimens. | it is estimated that faecal-orally transmitted diseases are common in afghanistan, as a consequence of poor hygienic standards of life and widespread contamination of water and food with both human and animal faeces. however, there is little information in the literature concerning infections caused by intestinal parasites in the afghan population. in this study, we report the occurrence of giardia intestinalis assemblages (a and b) in formalin-fixed stool samples collected from 245 afghan schoo ... | 2017 | 28612148 |
| histone methyltransferase 1 regulates the encystation process in the parasite giardia lamblia. | in eukaryotes, histone lysine methylation is associated with either active or repressed chromatin states, depending on the status of methylation. even when the amino-terminus of giardia lamblia histones diverges from other organisms, these regions contain lysine residues that are potential targets for methylation. when we examined the role of the histone methyltransferase 1 (hmt1) in the regulation of the encystation process by giardial histone methyltransferase 1 (glhmt1) overexpression or down ... | 2017 | 28605118 |
| prevalence of intestinal parasitoses detected in padua teaching hospital, italy, march 2011 - february 2013. | the aim of this study was to evaluate the distribution of parasitic intestinal infections in patients attending padua teaching hospital during a two-year period. between 1st march 2011 and 28th february 2013, we examined stool specimens from 7341 patients (6127 italians, 1214 non-italians) for ova and parasites using microscopy, rapid enzyme immunoassays, culture techniques and molecular methods. stools of 1080 patients (14.71%) were positive for parasites; a total of 1349 intestinal parasites w ... | 2017 | 28603232 |
| environmental transport of emerging human-pathogenic cryptosporidium species and subtypes through combined sewer overflow and wastewater. | the environmental transport of cryptosporidium spp. through combined sewer overflow (cso) and the occurrence of several emerging human-pathogenic cryptosporidium species in developing countries remain unclear. in this study, we collected 40 cso samples and 40 raw wastewater samples from shanghai, china, and examined them by pcr and dna sequencing for cryptosporidium species (targeting the small subunit rrna gene) and giardia duodenalis (targeting the triosephosphate isomerase, β-giardin, and glu ... | 2017 | 28600310 |
| prevalence of intestinal parasitic infection and associated risk factors among village health volunteers in rural communities of southern thailand. | intestinal parasitic infections remain prevalent and constitute a public health problem in certain rural areas of thailand. village health volunteers (vhvs), who are members of a thai healthcare alliance, function as key providers of health prevention measures, disease control, and health education and share national health promotion campaigns with community members. this study is aimed at evaluating the prevalence, intensity, and risk factors for intestinal parasitic infection in vhvs in order ... | 2017 | 28599633 |
| synthesis, antiprotozoal activity, and chemoinformatic analysis of 2-(methylthio)-1h-benzimidazole-5-carboxamide derivatives: identification of new selective giardicidal and trichomonicidal compounds. | a series of twelve new 2-(methylthio)-1h-benzimidazole-5-carboxamide derivatives (1-12) were synthesized and their antiparasitic activity was tested in vitro against giardia intestinalis, trichomonas vaginalis and entamoeba histolytica. experimental evaluations showed ic50 values within the nanomolar range for all tested compounds, some showing higher activity than metronidazole and albendazole. a chemoinformatic study was used to compare the structure-activity relationship of the synthesized ca ... | 2017 | 28595066 |
| distribution of parasites detected in stool samples of patients in le dantec university hospital of dakar, senegal, from 2011 to 2015. | to identify the parasites responsible for intestinal parasitic infections diagnosed at le dantec university hospital of dakar, distribution of parasites detected in stool samples of patients was studied. from 2011 to 2015, 2578 patients were included in the study. a direct examination and ritchie technique were performed as parasite search techniques. in total, 408 samples were positive showing 440 intestinal parasites; this corresponds to prevalence of 15.8%. parasites were detected in monopara ... | 2017 | 28588624 |
| analysis of parasitic protozoa at the single-cell level using microfluidic impedance cytometry. | at present, there are few technologies which enable the detection, identification and viability analysis of protozoan pathogens including cryptosporidium and/or giardia at the single (oo)cyst level. we report the use of microfluidic impedance cytometry (mic) to characterise the ac electrical (impedance) properties of single parasites and demonstrate rapid discrimination based on viability and species. specifically, mic was used to identify live and inactive c. parvum oocysts with over 90% certai ... | 2017 | 28572634 |
| high prevalence of enteroparasites in children from ribeirão preto, são paulo, brazil. | to determine the prevalence of intestinal parasites and possible associated factors. | 2017 | 28562805 |
| confirmation of a unique species of giardia, parasitic in the quenda (isoodon obesulus). | the 'quenda genotype' of giardia was first identified in quenda (syn. southern brown bandicoots, isoodon obesulus) in western australia in 2004. we aimed to formally describe this genotype as a species of giardia, giardia peramelis. seventy five faecal samples positive for g. peramelis were obtained from quenda within the statistical division of perth, western australia. these samples were used in morphological and molecular characterisation of g. peramelis. pcr amplification and sequencing was ... | 2016 | 28560164 |
| characterization of bip protein of g. lamblia as a potential immunogen in a mouse infection model. | giardia lamblia is a protozoan parasite that causes one of the most common gastrointestinal diseases worldwide. to eliminate the parasite from the host intestine, it is necessary the activation of b-cell and t-cell dependent mechanisms. the knowledge about giardia antigens that can stimulate the host immune response is limited. recently, it has been described the binding immunoglobulin protein (bip) of g. lamblia (71kda) as a potential immunogen. additionally, our group has identified a highly i ... | 2017 | 28552268 |
| high genetic diversity of giardia duodenalis assemblage e in pre-weaned dairy calves in shanghai, china, revealed by multilocus genotyping. | giardia duodenalis is a common parasitic protozoan in human and animals. epidemiological and molecular data are available from dairy cattle in many industrialized countries, but information on genetic diversity at multiple genetic loci is limited, especially in pre-weaned dairy calves. in this study, 818 fecal specimens were collected from five dairy cattle farms located in suburbs of shanghai, china, with two to five samplings per farm. g. duodenalis assemblages and subtypes were determined usi ... | 2017 | 28550644 |
| hookworm infection is associated with decreased cd4+ t cell counts in hiv-infected adult ugandans. | most studies evaluating epidemiologic relationships between helminths and hiv have been conducted in the pre-art era, and evidence of the impact of helminth infections on hiv disease progression remains conflicting. less is known about helminth infection and clinical outcomes in hiv-infected adults receiving antiretroviral therapy (art). we sampled hiv-infected adults for eight gastrointestinal parasites and correlated parasitic infection with demographic predictors, and clinical and immunologic ... | 2017 | 28542260 |
| measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels. | serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance. most methods to analyze antibody measurements reduce quantitative antibody levels to seropositive and seronegative groups, but this can be difficult for many pathogens and may provide lower resolution information than quantitative levels. analysis methods have predominantly maintained a single diseas ... | 2017 | 28542223 |
| an 18s rrna workflow for characterizing protists in sewage, with a focus on zoonotic trichomonads. | microbial eukaryotes (protists) are important components of terrestrial and aquatic environments, as well as animal and human microbiomes. their relationships with metazoa range from mutualistic to parasitic and zoonotic (i.e., transmissible between humans and animals). despite their ecological importance, our knowledge of protists in urban environments lags behind that of bacteria, largely due to a lack of experimentally validated high-throughput protocols that produce accurate estimates of pro ... | 2017 | 28540488 |
| antiprotozoal activities of tiliroside and other compounds from sphaeralcea angustifolia (cav.) g. don. | sphaeralcea angustifolia (malvaceae) is extensively used in mexican traditional medicine for the treatment of gastrointestinal disorders such as diarrhea and dysentery. | 2017 | 28539736 |
| antiprotozoal, antibacterial and antidiarrheal properties from the flowers of chiranthodendron pentadactylon and isolated flavonoids. | chiranthodendron pentadactylon larreat. (sterculiaceae) is a mexican plant used in traditional medicine for the treatment of heart disease symptoms and infectious diarrhea. | 2017 | 28539715 |
| piqueria trinervia as a source of metabolites against giardia intestinalis. | piqueria trinervia cav. (asteraceae) is a plant species with a long history in traditional medicine to cure diarrhoea and other digestive disorders. | 2017 | 28524742 |
| a novel spliceosome-mediated trans-splicing can change our view on genome complexity of the divergent eukaryote giardia intestinalis. | although spliceosomal introns are an abundant landmark in eukaryotic genomes, the nuclear genome of the divergent eukaryote giardia intestinalis, the causative agent of giardiasis, has been considered as "intron-poor" with only five canonical (cis-spliced) introns. however, three research groups (including ours) have independently reported a novel class of spliceosomal introns in the g. intestinalis genome. three protein-coding genes are split into pieces in the g. intestinalis genome, and each ... | 2011 | 28510047 |
| intestinal parasitic infections and its association with undernutrition and cd4 t cell levels among hiv/aids patients on haart in butajira, ethiopia. | intestinal parasitic infections and hiv/aids have been the major public health problems and remain a vital cause of morbidity and mortality in developing countries. both problems are linked in a vicious cycle. the magnitude of intestinal parasites was prevalent among people living with hiv/aids even in the haart era. however, the pertinent risk factors associated with intestinal parasites among hiv/aids patients were not well investigated in ethiopia particularly at butajira town. therefore, the ... | 2017 | 28506307 |
| antigiardial activity of podophyllotoxin-type lignans from bursera fagaroides var. fagaroides. | giardiasis, a diarrheal disease, is highly prevalent in developing countries. several drugs are available for the treatment of this parasitosis; unfortunately, all of them have variable efficacies and adverse effects. bursera fagaroides has been known for its anti-inflammatory and antidiarrheal properties in mexican traditional medicine. we investigated the in vitro anti-giardial activities of four podophyllotoxin-type lignans from bursera fagaroides var. fagaroides, namely, 5'-desmethoxy-β-pelt ... | 2017 | 28505094 |
| molecular typing of giardia duodenalis in humans in queensland - first report of assemblage e. | little is known about the genetic diversity of the protozoan parasite, giardia duodenalis, infecting humans in queensland, australia. the present study typed 88 microscopically giardia-positive isolates using assemblage-specific primers at the triose phosphate isomerase (tpi) gene and sequenced a subset of isolates at the glutamate dehydrogenase (gdh) gene (n = 30) and tpi locus (n = 27). using the tpi-assemblage specific primers, g. duodenalis assemblage a and assemblage b were detected in 50% ... | 2017 | 28482937 |
| structural characterization of giardia duodenalis thioredoxin reductase (gtrxr) and computational analysis of its interaction with nbdhex. | giardia duodenalis is a microaerophilic parasite that colonizes the upper portions of the small intestine of humans. giardia infection is a major contributor to diarrheal disease worldwide. nitroheterocycles (e.g. metronidazole) or benzimidazoles (e.g. albendazole) are the most commonly used therapeutic agents. unfortunately, their efficacy is reduced by low compliance or resistance phenomena. we recently discovered that the antitumoral drug 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (nbdhe ... | 2017 | 28477573 |
| curcumin alters the cytoskeleton and microtubule organization on trophozoites of giardia lamblia. | giardia lamblia is a worldwide protozoan responsible for a significant number of intestinal infections. there are several drugs for the treatment of giardiasis, but they often cause side effects. curcumin, a component of turmeric, has antigiardial activity; however, the molecular target and mechanism of antiproliferative activity are not clear. the effects of curcumin on cellular microtubules have been widely investigated. since tubulin is the most abundant protein in the cytoskeleton of giardia ... | 2017 | 28465123 |
| occurrence and removal efficiency of parasitic protozoa in swedish wastewater treatment plants. | giardia intestinalis, cryptosporidium spp., entamoeba histolytica and dientamoeba fragilis are parasitic protozoa and causative agents of gastroenteritis in humans. g. intestinalis and cryptosporidium spp. in particular are the most common protozoa associated with waterborne outbreaks in high-income countries. surveillance of protozoan prevalence in wastewater and evaluation of wastewater treatment removal efficiencies of protozoan pathogens is therefore imperative for assessment of human health ... | 2017 | 28458199 |
| associations of giardia lamblia assemblages with hiv infections and symptomatology: hiv virus and assemblage b were they born to each other? | giardia lamblia is an intestinal parasite that has an extensive genetic variation among isolates. this species is divided into eight different assemblages (a-h), but only assemblages a and b have been associated with human infections. studies on the associations of g. lamblia assemblages and symptoms have been done but were inconclusive. the aim of this study was to correlate g. lamblia assemblages with symptoms in patients with and without hiv/aids and its association with the cd4t cell count. ... | 2017 | 28456597 |
| phosphoinositide binding profiles of the px domains of giardia lamblia. | the membrane trafficking machinery that functions at the endomembrane system of giardia lamblia appears to be significantly different from that present in most model eukaryotes. this machinery is important for encystation as cyst wall material is trafficked to the cell surface via encystation-specific vesicles. since proteins containing the phosphoinositide-binding px domains are known regulators of vesicular trafficking, blast search was used to identify the px domains of g. lamblia. six putati ... | 2017 | 28456494 |
| the use of quinacrine in nitroimidazole-resistant giardia duodenalis: an old drug for an emerging problem. | there is little evidence regarding the management of refractory giardiasis after treatment with nitroimidazoles. this study estimates the proportion of persistent giardiasis in 3 hospitals in barcelona, describes associated risk factors and genotype, and evaluates the efficacy rate of quinacrine in those with persistent giardiasis. | 2017 | 28453841 |
| interactions of giardia sp. with the intestinal barrier: epithelium, mucus, and microbiota. | understanding how intestinal enteropathogens cause acute and chronic alterations has direct animal and human health perspectives. significant advances have been made on this field by studies focusing on the dynamic crosstalk between the intestinal protozoan parasite model giardia duodenalis and the host intestinal mucosa. the concept of intestinal barrier function is of the highest importance in the context of many gastrointestinal diseases such as infectious enteritis, inflammatory bowel diseas ... | 2017 | 28452685 |
| multiplex pcr detection of cryptosporidium sp, giardia lamblia and entamoeba histolytica directly from dried stool samples from guinea-bissauan children with diarrhoea. | in developing countries, diarrhoea is the most common cause of death for children under five years of age, with giardia lamblia, cryptosporidium and entamoeba histolytica as the most frequent pathogenic parasites. traditional microscopy for stool parasites has poor sensitivity and specificity, while new molecular methods may provide more accurate diagnostics. in poor regions with sample storage hampered by uncertain electricity supply, research would benefit from a method capable of analysing dr ... | 2017 | 28446068 |
| molecular characterization of cryptosporidium and giardia from the tasmanian devil (sarcophilus harrisii). | the tasmanian devil (sarcophilus harrisii) is a carnivorous marsupial found only in the wild in tasmania, australia. tasmanian devils are classified as endangered and are currently threatened by devil facial tumour disease, a lethal transmissible cancer that has decimated the wild population in tasmania. to prevent extinction of tasmanian devils, conservation management was implemented in 2003 under the save the tasmanian devil program. this study aimed to assess if conservation management was a ... | 2017 | 28423030 |
| prevalence and molecular characterization of cryptosporidium spp. and giardia duodenalis in diarrhoeic patients in the qikiqtani region, nunavut, canada. | background although the prevalences of infection with the protozoan parasites cryptosporidium spp. and giardia duodenalis in humans appear to be relatively high in the canadian north, their transmission patterns are poorly understood. objective to determine the detection rate and the molecular characteristics of cryptosporidium spp. and giardia duodenalis in diarrhoeic patients in the qikiqtani (baffin island) region of nunavut, canada, in order to better understand the burden of illness and the ... | 2015 | 28417809 |
| cryptosporidium spp. and giardia spp. in feces and water and the associated exposure factors on dairy farms. | the aims of this study were to verify the prevalence of cryptosporidium spp. and giardia spp. in animal feces and drinking water on dairy farms and to identify a possible relation between the exposure factors and the presence of these parasites. fecal samples from cattle and humans and water samples were collected on dairy farms in paraná, brazil. analysis of (oo)cysts in the feces was performed by the modified ziehl-neelsen staining and centrifugal flotation in zinc sulfate. test-positive sampl ... | 2017 | 28403147 |
| giardiasis outbreak associated with asymptomatic food handlers in new york state, 2015. | giardia duodenalis is a protozoan that causes a gastrointestinal illness called giardiasis. giardiasis outbreaks in the united states are most commonly associated with waterborne transmission and are less commonly associated with food, person-to-person, and zoonotic transmission. during june to september 2015, an outbreak of 20 giardiasis cases occurred and were epidemiologically linked to a local grocery store chain on long island, new york. further investigation revealed three asymptomatic foo ... | 2017 | 28402185 |
| click chemistry-facilitated structural diversification of nitrothiazoles, nitrofurans, and nitropyrroles enhances antimicrobial activity against giardia lamblia. | giardia lamblia is an important and ubiquitous cause of diarrheal disease. the primary agents in the treatment of giardiasis are nitroheterocyclic drugs, particularly the imidazoles metronidazole and tinidazole and the thiazole nitazoxanide. although these drugs are generally effective, treatment failures occur in up to 20% of cases, and resistance has been demonstrated in vivo and in vitro prior work had suggested that side chain modifications of the imidazole core can lead to new effective 5-n ... | 2017 | 28396548 |
| giardia alters commensal microbial diversity throughout the murine gut. | giardia lamblia is the most frequently identified protozoan cause of intestinal infection. over 200 million people are estimated to have acute or chronic giardiasis, with infection rates approaching 90% in areas where giardia is endemic. despite its significance in global health, the mechanisms of pathogenesis associated with giardiasis remain unclear, as the parasite neither produces a known toxin nor induces a robust inflammatory response. giardia colonization and proliferation in the small in ... | 2017 | 28396324 |
| prevalence and molecular characterization of giardia duodenalis in dogs in aydin, turkey. | the purpose of the present study was to investigate the prevalence and molecular characterization of giardia duodenalis among dogs in aydin, turkey. a total of 473 faecal samples from dogs were collected. the overall prevalence of g. duodenalis was 18.8%. higher infection rates were observed in dogs younger than three months old, from shelters, and with diarrhoea. faecal samples of 89 dogs, diagnosed giardia-positive by microscopy, were found positive by nested pcr. the β-giardin nested pcr assa ... | 2017 | 28374629 |
| experimental and bioinformatic characterization of cabp2933 an ef-hand protein of giardia intestinalis. | giardia intestinalis is a parasite that inhabits the small intestine of humans. this parasite is a divergent eukaryote with a compact genome. the calcium ion is an essential messenger in cell signaling. calcium's role as a messenger is mediated through calcium-binding proteins (cabps) that decode the message. the most important family of cabps is the ef-hand protein family. in this study we have explored the role of ef-hand protein cabp2933. we analyzed its location, confirmed its ability to bin ... | 2017 | 28373093 |
| giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum. | mitochondria of opisthokonts undergo permanent fission and fusion throughout the cell cycle. here, we investigated the dynamics of the mitosomes, the simplest forms of mitochondria, in the anaerobic protist parasite giardia intestinalis, a member of the excavata supergroup of eukaryotes. the mitosomes have abandoned typical mitochondrial traits such as the mitochondrial genome and aerobic respiration and their single role known to date is the formation of iron-sulfur clusters. | 2017 | 28372543 |
| transcriptomics indicates active and passive metronidazole resistance mechanisms in three seminal giardia lines. | giardia duodenalis is an intestinal parasite that causes 200-300 million episodes of diarrhoea annually. metronidazole (mtz) is a front-line anti-giardial, but treatment failure is common and clinical resistance has been demonstrated. mtz is thought to be activated within the parasite by oxidoreductase enzymes, and to kill by causing oxidative damage. in g. duodenalis, mtz resistance involves active and passive mechanisms. relatively low activity of iron-sulfur binding proteins, namely pyruvate: ... | 2017 | 28367140 |
| proteomic and functional analyses reveal pleiotropic action of the anti-tumoral compound nbdhex in giardia duodenalis. | giardiasis, a parasitic diarrheal disease caused by giardia duodenalis, affects one billion people worldwide. treatment relies only on a restricted armamentarium of drugs. the disease burden and the increase in treatment failure highlight the need for novel, safe and well characterized drug options. the antitumoral compound nbdhex is effective in vitro against giardia trophozoites and inhibits glycerol-3-phosphate dehydrogenase. aim of this work was to search for additional nbdhex protein target ... | 2017 | 28366863 |
| the effects of phosphanegold(i) thiolates on the biological properties of acanthamoeba castellanii belonging to the t4 genotype. | gold compounds have shown promise in the treatment of non-communicable diseases such as rheumatoid arthritis and cancer, and are considered of value as anti-microbial agents against gram-negative and gram-positive bacteria, and have anti-parasitic properties against schistosoma mansoni, trypanosoma brucei, plasmodium falciparum, leishmania infantinum, giardia lamblia, and entamoeba histolytica. they are known to affect enzymatic activities that are required for the cellular respiration processes ... | 2017 | 28366172 |
| use of translation blocking morpholinos for gene knockdown in giardia lamblia. | giardia lamblia, a major parasite, is an emerging model organism due to its compact genomic arrangement and composition. the most popular reverse genetic technique, rnai, is ineffective in giardia. in contrast, protein depletion by translation blocking morpholinos is suitable for most gene targets and provides up to 80% depletion of the target protein. the method is fast, reliable, and specific. after antisense morpholino oligomer delivery into giardia trophozoites by electroporation, the cells ... | 2017 | 28364239 |
| occurrence of giardia in swedish red foxes ( vulpes vulpes ). | giardia duodenalis is an intestinal protozoan capable of causing gastrointestinal disease in a range of vertebrate hosts. it is transmitted via the fecal-oral route. understanding the epidemiology of g. duodenalis in animals is important, both for public health and for the health of the animals it infects. we investigated the occurrence of g. duodenalis in wild swedish red foxes ( vulpes vulpes ), with the aim of providing preliminary information on how this abundant predator might be involved i ... | 2017 | 28362140 |
| intestinal parasitic infections in different groups of immunocompromised patients in kashan and qom cities, central iran. | intestinal parasitic infections (ipis) are important causes of morbidity and mortality in patients with immunocompromising conditions. | 2017 | 28362138 |
| prevalence of entamoeba histolytica, giardia lamblia, and cryptosporidium spp. in libya: 2000-2015. | introduction the intestinal protozoa entamoeba histolytica, giardia lamblia, and cryptosporidium spp. are the causative agents of giardiasis, amebiasis, and cryptosporidiosis, respectively. adequate knowledge of the geographical distribution of parasites and the demographic variables that influence their prevalence is important for effective control of infection in at-risk populations. methods the data were obtained by an english language literature search of medline and pubmed for papers using ... | 2016 | 28349839 |
| giardia-filled pancreatic mass in a patient with recently treated t-cell-rich b-cell lymphoma. | giardia lamblia (g. lamblia)-filled pancreatic masses are a rarely reported entity. furthermore, there are only a few case reports in literature on the association of these masses with cancer. we present a case of a g. lamblia-filled pancreatic cystic mass in a patient with a history of t-cell-rich b-cell lymphoma. the authors performed a pubmed search using (medical subject headings) mesh terms of pancreas, mass, giardia, and lymphoma. a 53-year-old male with past medical and surgical history ... | 2017 | 28348938 |
| from good health to illness with post-infectious fatigue syndrome: a qualitative study of adults' experiences of the illness trajectory. | municipal drinking water contaminated with the parasite giardia lamblia in bergen, norway, in 2004 caused an outbreak of gastrointestinal infection in 2500 people, according to the norwegian prescription database. in the aftermath a minor group subsequently developed post-infectious fatigue syndrome (pifs). persons in this minor group had laboratory-confirmed parasites in their stool samples, and their enteritis had been cured by one or more courses of antibiotic treatment. the study's purpose w ... | 2017 | 28347294 |
| association between parasitic infections and tuberculin skin test results in refugees. | parasitic infections are known to modulate the immune response necessary for controlling mycobacterium tuberculosis infection. we sought to investigate species-specific effects of parasite infection on m. tuberculosis infection. | 2017 | 28342825 |
| giardiasis and subsequent irritable bowel syndrome: a longitudinal cohort study using health insurance data. | giardia intestinalis is the most commonly reported human intestinal parasite in the united states. increased incidence of chronic gastrointestinal complaints has been reported after some giardiasis outbreaks. we examined the relationship between giardiasis diagnosis and irritable bowel syndrome (ibs) diagnosis. | 2017 | 28329069 |