Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| pcr-based identification of trypanosoma lewisi and trypanosoma musculi using maxicircle kinetoplast dna. | trypanosoma lewisi, transmitted by rat fleas, is a widespread pathogen specific to rats with records of human infection cases. its closely related species with global distribution, trypanosoma musculi, is transmitted between mice by ingestion of infected fleas. these trypanosomes are of similar morphology, making it difficult to distinguish them by microscopy. in this study, we have developed a rapid, sensitive and reliable pcr method for the diagnosis of t. lewisi and t. musculi. the t. lewisi- ... | 2017 | 28427957 |
| rodent-borne trypanosoma from cities and villages of niger and nigeria: a special role for the invasive genus rattus? | although they are known to sometimes infect humans, atypical trypanosomes are very poorly documented, especially in africa where one lethal case has yet been described. here we conducted a survey of rodent-borne trypanosoma in 19 towns and villages of niger and nigeria, with a special emphasis on niamey, the capital city of niger. the 1,298 rodents that were captured yielded 189 qpcr-positive animals from 14 localities, thus corresponding to a 14.6% overall prevalence. rats, especially black rat ... | 2017 | 28373037 |
| condition factor and organosomatic indices of parasitized rattus rattus as indicators of host health. | this study describes the influence of parasitism (trypanosoma lewisi and cysticercus fasciolaris) on the condition factor, hepato and splenosomatic indices of the common house rat, rattus rattus linnaeus, 1758 from rohilkhand, uttar pradesh, india. examination of r. rattus (n = 389) revealed t. lewisi (prevalence 12.40 %; intensity14 parasites/1000 rbc) from the blood and c. fasciolaris (larval taenia taeniaeformis) (prevalence 46.70 %; intensity 2-4 par/host) from the liver. condition factor (k ... | 2017 | 28316383 |
| fleas and trypanosomes of peridomestic small mammals in sub-saharan mali. | fleas are obligate blood-feeding ectoparasites and vectors of several bacterial zoonotic pathogens as well as trypanosomes that parasitize rodents and other small mammals. during investigations of tick- and rodent-borne diseases in mali, west africa, we included fleas and rodent-borne trypanosomes, both of which are poorly known in this country, but are attracting greater public health interest. | 2016 | 27724960 |
| impact of anthropogenic disturbance on native and invasive trypanosomes of rodents in forested uganda. | habitat disturbance and anthropogenic change are globally associated with extinctions and invasive species introductions. less understood is the impact of environmental change on the parasites harbored by endangered, extinct, and introduced species. to improve our understanding of the impacts of anthropogenic disturbance on such host-parasite interactions, we investigated an invasive trypanosome (trypanosoma lewisi). we screened 348 individual small mammals, representing 26 species, from both fo ... | 2016 | 27655649 |
| zoonotic trypanosomes in south east asia: attempts to control trypanosoma lewisi using human and animal trypanocidal drugs. | beside typical human trypanosomes responsible of sleeping sickness in africa and chagas disease in latin america, there is a growing number of reported atypical human infections due to trypanosoma evansi, a livestock parasite, or trypanosoma lewisi, a rat parasite, especially in asia. drugs available for the treatment of t. brucei ssp. in humans are obviously of choice for the control of t. evansi because it is derived from t. brucei. however, concerning t. lewisi, there is an urgent need to det ... | 2016 | 27491458 |
| surveillance of trypanosoma spp of rodents and studies in their transmission probability by fleas in some rural egyptian areas. | a new public health problem arises from animal trypanosomes that afflict human by a disease called atypical human trypanosomiasis. although humans have an innate protection against most trypanosoma species, nineteen cases of atypical human trypanosomiasis caused by the animal trypanosome as t. b. brucei, t. vivax, t. congolense, t. evansi and t. lewisi have been recorded. some of theserecorded cases were transient, six required trypanocidal treatments however two patients died. rodent trypanosom ... | 2016 | 27363052 |
| phylogenetic analysis of the trypanosoma genus based on the heat-shock protein 70 gene. | trypanosome evolution was so far essentially studied on the basis of phylogenetic analyses of small subunit ribosomal rna (ssu-rrna) and glycosomal glyceraldehyde-3-phosphate dehydrogenase (ggapdh) genes. we used for the first time the 70kda heat-shock protein gene (hsp70) to investigate the phylogenetic relationships among 11 trypanosoma species on the basis of 1380 nucleotides from 76 sequences corresponding to 65 strains. we also constructed a phylogeny based on combined datasets of ssu-rdna, ... | 2016 | 27180897 |
| protozoan parasites of rodents and their zoonotic significance in boyer-ahmad district, southwestern iran. | backgrounds. wild rodents are reservoirs of various zoonotic diseases, such as toxoplasmosis, babesiosis, and leishmaniasis. the current study aimed to assess the protozoan infection of rodents in boyer-ahmad district, southwestern iran. materials and methods. a total of 52 rodents were collected from different parts of boyer-ahmad district, in kohgiluyeh and boyer-ahmad province, using sherman live traps. each rodent was anesthetized with ether, according to the ethics of working with animals, ... | 2016 | 26998380 |
| zoonotic trypanosomes in south east asia: attempts to control trypanosoma lewisi using veterinary drugs. | a growing number of atypical human infections due to the livestock parasite trypanosoma evansi, or to the rat parasite trypanosoma lewisi, are reported in humans in asia. in some cases, clinical evolutions request treatments, however, so far, there were very few attempts to control t. lewisi using trypanocidal drugs. in a study published elsewhere, the efficacy of human trypanocides is evaluated in laboratory rats, and it concludes that none of them is able to cure rats experimentally infected w ... | 2016 | 26988923 |
| erratum to: analysis of the mitochondrial maxicircle of trypanosoma lewisi, a neglected human pathogen. | 2016 | 26762513 | |
| analysis of the mitochondrial maxicircle of trypanosoma lewisi, a neglected human pathogen. | the haemoflagellate trypanosoma lewisi is a kinetoplastid parasite which, as it has been recently reported to cause human disease, deserves increased attention. characteristic features of all kinetoplastid flagellates are a uniquely structured mitochondrial dna or kinetoplast, comprised of a network of catenated dna circles, and rna editing of mitochondrial transcripts. the aim of this study was to describe the kinetoplast dna of t. lewisi. | 2015 | 26715306 |
| [identification of trypanosoma species in rattus flavipectus and r. losea using microscopy and pcr method]. | to identify two suspected trypanosoma species in rattus found in zhejiang province using microscopy and pcr method. | 2015 | 26672218 |
| resistance to normal human serum reveals trypanosoma lewisi as an underestimated human pathogen. | human-infectious trypanosomes such as trypanosoma cruzi, t. brucei rhodesiense, and t. b. gambiense can be discriminated from those only infecting animals by their resistance to normal human serum (nhs). these parasites are naturally resistant to trypanolysis induced by the human-specific pore-forming serum protein apolipoprotein l1 (apol-1). t. lewisi, a worldwide distributed parasite, has been considered as rat-specific and non-pathogenic to the natural hosts. here we provide evidence that 19 ... | 2016 | 25858024 |
| trypanosoma from rodents as potential source of infection in human-shaped landscapes of south-east asia. | reports of atypical human cases of trypanosoma lewisi or t. lewisi-like and trypanosoma evansi infections have increased in south-east asia, urging to investigate the possible links between humans, animal reservoirs and habitats. we tested how habitat structure affects the infection by trypanosoma species of common murine rodents, inhabiting human-dominated landscapes in south east asia. for this, we used geo-referenced data of rodents investigated for trypanosoma infection and land cover maps p ... | 2015 | 25613476 |
| comparison between quantitative buffy coat (qbc) and giemsa-stained thin film (gtf) technique for blood protozoan infections in wild rats. | the quantitative buffy coat (qbc) technique and conventional giemsa thin blood smear was compared to determine the sensitivity and specificity of the technique in detecting blood parasitic infection of the rodent populations from four urban cities in peninsular malaysia. a total of 432 blood samples from four rat species (rattus norvegicus, rattus rattus diardii, rattus exulans and rattus argentiventer) were screened using both techniques and successfully detected two blood protozoan species (tr ... | 2014 | 25382468 |
| on opportunist infections by trypanosoma lewisi in humans and its differential diagnosis from t. cruzi and t. rangeli. | trypanosoma lewisi is a cosmopolitan species originally found in rattus spp., being nonpathogenic, host-restricted, and transmitted by rat fleas. this species has been recorded as an opportunist blood parasite of human beings mainly in asia, with a case in africa. in brazil, this species was recently recorded in captive monkeys. as t. lewisi can share vertebrate hosts both with trypanosoma rangeli and trypanosoma cruzi, some markers for the differential diagnosis of these species were examined a ... | 2014 | 25216782 |
| trypanosomes of australian mammals: a review. | approximately 306 species of terrestrial and arboreal mammals are known to have inhabited the mainland and coastal islands of australia at the time of european settlement in 1788. the exotic trypanosoma lewisi was the first mammalian trypanosome identified in australia in 1888, while the first native species, trypanosoma pteropi, was taxonomically described in 1913. since these discoveries, about 22% of the indigenous mammalian fauna have been examined during the surveillance of trypanosome biod ... | 2014 | 25161902 |
| epidemiology of blood parasitic infections in the urban rat population in peninsular malaysia. | a total of 719 wild rats were captured from four localities representing the west (kuala lumpur), east (kuantan), north (georgetown) and south (malacca) to determine the diversity of blood protozoan from the urban wild rat population in peninsular malaysia. five rat species were recovered with rattus rattus diardii being the most dominant species, followed by rattus norvegicus, rattus exulans, rattus annandalei and rattus argentiventer. two blood protozoan species were found infecting the rodent ... | 2014 | 25134892 |
| [atypical human trypanosomoses]. | trypanosomes are principally responsible for two human diseases: human african trypanosomiasis (hat) or sleeping sickness (caused by trypanosoma brucei gambiense and t. b. rhodesiense), and chagas disease, also called south american trypanosomiasis (t. cruzi). however, some trypanosomes that are natural parasites only of animals can sometimes infect humans and cause the so-called "atypical human trypanosomiases" (aht). t. evansi, the agent causing surra in camels, horses, dogs, and bovines, and ... | 2016 | 24918468 |
| evaluation of trypanocidal drugs used for human african trypanosomosis against trypanosoma lewisi. | trypanosomes from animals are potential pathogens for humans. several human cases infected by trypanosoma lewisi, a parasite of rats, have been reported. the number of these infections is possibly underestimated. some infections were self-cured, others required treatment with drugs used in human african trypanosomosis. an in vitro evaluation of these drugs and fexinidazole, a new oral drug candidate, has been performed against t. lewisi in comparison with t. brucei gambiense. all have comparable ... | 2013 | 24139487 |
| molecular prevalence of trypanosoma spp. in wild rodents of southeast asia: influence of human settlement habitat. | this study investigated the molecular prevalence of trypanosoma lewisi and t. evansi in wild rodents from cambodia, lao pdr and thailand. between 2008 and 2012, rodents (and shrews) were trapped in nine locations and 616 of these were tested using three sets of primers: tryp1 (amplifying its1 of ribosomal dna of all trypanosomes), tbr (amplifying satellite genomic dna of trypanozoon parasites) and lew1 (amplifying its1 of ribosomal dna of t. lewisi). based on the size of the pcr products using t ... | 2014 | 24025128 |
| [immunosuppressor effect of trypanosoma musculi (mastigophora: trypanosomatidae) on experimental toxoplasmosis]. | the immunosuppression caused by species of the gender trypanosoma has been widely documented. the influence over experimental infections with toxoplasma gondii is evident when using trypanosoma lewisi, a natural parasite of white rats. we decided to test the effect of trypanosoma musculi from mice, an organism with very similar biological characteristics to t. lewisi, to see if this trypanosomatid could induce a similar effect. four groups of swiss mice were inoculated with t. musculi previously ... | 2013 | 23885603 |
| emerging protozoal pathogens in india: how prepared are we to face the threat? | emerging protozoal pathogens have become a major threat to human health. the number of protozoal pathogens causing human disease has been on the rise since the last two to three decades. significant increase in the number of immunocompromised people, increase in international travel, deforestation, and widespread urban dwellings are some of the factors contributing to this changing epidemiology of protozoal diseases. apart from naegleria and acanthamoeba, other free-living amoebae like balamuthi ... | 0 | 23508066 |
| prevalence of intestinal and blood parasites among wild rats in kuala lumpur, malaysia. | a survey was undertaken to investigate the prevalence of intestinal and blood parasites among wild rats in urban area of kuala lumpur, malaysia. a total of 137 stool and blood samples were collected from wild rats from sentul and chow kit areas. five species of rats were captured and supplied by kuala lumpur city hall. the most common was rattus rattus diardii (malayan black rat), 67%, followed by rattus norvegicus (norway rat), 10%, rattus argentiventer (rice-field rat), 10%, rattus tiomanicus ... | 2012 | 23202599 |
| detection of trypanosoma lewisi from wild rats in southern china and its genetic diversity based on the its1 and its2 sequences. | trypanosoma lewisi has widely been considered as a non-pathogenic rat trypanosome. however, more and more cases of humans infected with t. lewisi have been reported around the world, indicating that it can infect humans in some undetermined circumstances. quick and sensitive diagnosis of infection by t. lewisi is important for both treatment of patients and epidemiological studies of this parasite. in this paper, three methods i.e. wet blood smear (diagnosis by microscopy), pcr and lamp were use ... | 2012 | 22449774 |
| molecular demonstration of trypanosoma evansi and trypanosoma lewisi dna in wild rodents from cambodia, lao pdr and thailand. | in this study, we investigated the molecular evidence of trypanosoma evansi in wild rodents from cambodia, lao pdr and thailand. between november 2007 and june 2009, 1664 rodents were trapped at eight sites representative of various ecological habitats. of those animals, 94 were tested by direct microscopic blood examination, 633 using the card agglutination test for trypanosomes (catt/t. evansi) and 145 by polymerase chain reaction (pcr) with two sets of primers: tryp1 (amplifying its1 of ribos ... | 2013 | 22321449 |
| trypanosoma lewisi or t. lewisi-like infection in a 37-day-old indian infant. | abstract. trypanosomes were observed in the peripheral blood smear of a 37-day-old indian infant admitted off feeds, with fever and convulsions. trypanosoma (herpetosoma) lewisi was identified in the blood. the species identification was confirmed by morphometry, polymerase chain reaction, and sequencing. human infection with this organism is rare. only seven cases of this infection have been reported previously in humans. the cases reported are reviewed to develop a composite picture of this di ... | 2011 | 21813838 |
| trypanosomiasis in an infant from india. | 2011 | 21715739 | |
| specific primers for pcr amplification of the its1 (ribosomal dna) of trypanosoma lewisi. | trypanosoma lewisi is a mild or non-pathogenic parasite of the sub-genus herpetosoma transmitted by fleas to rats. in a previous study we described pan-trypanosome specific primers tryp1 which amplify the its1 of ribosomal dna by hybridizing in highly conserved regions of 18s and 5.8s genes. these primers proved to be useful for detecting t. lewisi dna in laboratory rats, but a recent large scale survey in wild rodents demonstrated a lack of specificity. in the present study, we designed and eva ... | 2011 | 21570489 |
| molecular survey of rodent-borne trypanosoma in niger with special emphasis on t. lewisi imported by invasive black rats. | invading rodent species can harbor parasites with potential transmission to native rodents and/or humans. to investigate trypanosomes prevalence in rodents, the spleen of 76 rodents from niger identified by their karyotype was used as a dna source for trypanosoma detection using a newly developed qpcr assay. of the invasive black rat, rattus rattus, 71% (10/14) were pcr positive as well as 6% (4/62) of native african rodents. sequences of ~400bp of the ssu rdna gene identified phylogenetically c ... | 2010 | 21126503 |
| studies in trypanosomiasis; the fragility of the erythrocytes in rats during the course of infection with trypanosoma lewisi, trypanosoma brucei and trypanosoma equiperdum. | 1946 | 20996738 | |
| studies in trypanosomiasis; the serum potassium levels of rats during infection with trypanosoma lewisi, trypanosoma brucei, and trypanosoma equiperdum. | 1946 | 20996736 | |
| on the occurrence of an intracellular stage in the development of trypanosoma lewisi in the rat-flea. | 1911 | 20765763 | |
| the transmission of trypanosoma lewisi by the rat-flea (ceratophyllus fasciatus). | 1911 | 20765658 | |
| the mechanism of transmission of trypanosoma lewisi from rat to rat by the rat flea. | 1911 | 20765607 | |
| resumption of the reproductive phase of trypanosoma lewisi in recovered and near recovered rats following both reinoculation with the parasite and treatment with sodium salicylate. | 1947 | 20340871 | |
| the antigenic composition and the effect of various extracts of trypanosoma equiperdum and trypanosoma lewisi on the leucocyte picture in experimental trypanosomiasis. | 1947 | 20292036 | |
| prolongment of the reproductive phase of trypanosoma lewisi by the administration of sodium salicylate. | 1947 | 20265536 | |
| the effect of pantothenate deficiency on trypanosoma lewisi infection in the rat. | 1947 | 20250908 | |
| phylogenetic, morphological and behavioural analyses support host switching of trypanosoma (herpetosoma) lewisi from domestic rats to primates. | we characterized four brazilian trypanosomes isolated from domestic rats and three from captive non-human primates that were morphologically similar to t. lewisi, a considered non-pathogenic species restricted to rodents and transmitted by fleas, despite its potential pathogenicity for infants. these isolates were identified as t. lewisi by barcoding using v7v8 ssu rdna sequences. in inferred phylogenetic trees, all isolates clustered tightly with reference t. lewisi and t. lewisi-like trypanoso ... | 2010 | 20156599 |
| trypanosoma lewisi in boston rats. | 1921 | 19972551 | |
| artificial acidosis in trypanosoma lewisi infections, and its bearing on the pathogenic action of trypanosoma equiperdum. | when the alkali reserve is artificially lowered in rats infected with trypanosoma lewisi, the number of parasites in the blood is increased. the increase is large in the early stages of the disease, and becomes less marked as the number crisis is approached. near the crisis, and after it, a lowered alkali reserve does not affect the number of trypanosomes. it has been shown that the observed increase does not result from a contraction of the capillaries of the inner organs, which would throw a l ... | 1931 | 19869949 |
| a comparison of the chemical alterations in the blood of rats infected with pathogenic and non-pathogenic trypanosomes. | blood samples from rats infected with trypanosoma lewisi give normal values for lipoid phosphorus, lecithin, co(2) combining capacity, and liver glycogen. when these results are compared with the results of similar experiments with t. equiperdum infections, on the basis of the concentration of trypanosomes in the blood, it is found that the pathogenicity of the latter organism does not depend upon its numbers as affecting the blood, but that it must be in some other way injurious to the host. wh ... | 1930 | 19869797 |
| immunological studies in relation to the suprarenal gland : vi a. trypanosoma lewisi infection in normal albino rats vi b. trypanosoma lewisi infection in suprarenalectomized adult albino rats. | bilateral suprarenalectomy in rats lowers the resistance to a subsequent infection with t. lewisi. almost 70 per cent of these rats die within an average period of 5.8 days after infection. the multiplication of the parasites in the circulating stream is not more considerable than in rats previously normal nor is the duration of the disease in the surviving rats any longer than in the normal group. bilateral suprarenalectomy does not prevent the formation of immune substances to the parasites bu ... | 1930 | 19869790 |
| studies on bartonella muris anemia of albino rats : i. trypanosoma lewisi infection in normal albino rats associated with bartonella muris anemia ii. latent infection in adult normal rats. | 1. the virus of bartonella muris anemia of splenectomized rats may be transmitted to normal young unoperated rats and rabbits. this confirms the observations of ford and eliot. 2. trypanosoma lewisi infections in normal adult rats are accompanied by an anemia most marked at the height of the infection and the appearance of bartonella muris bodies in the red blood cells. 3. in young rats trypanosoma lewisi may produce death from the severity of the anemia, complicating the disease. the anemic vir ... | 1930 | 19869745 |
| a reaction product in infections with trypanosoma lewisi which inhibits the reproduction of the trypanosomes. | 1. in infections with trypanosoma lewisi in the rat there are three manifestations of resistance against the parasite: (1) the retardation and final inhibition of reproduction of the trypanosomes by about the 10th day; (2) a sudden drop in the number of parasites in the blood between the 9th and 15th days; and (3) the total disappearance of the parasites, which terminates the infection and occurs from a week to several months after the first drop in numbers. 2. the first manifestation of resista ... | 1924 | 19868831 |
| concerning changes in the biological properties of trypanosoma lewisi produced by experimental means, with especial reference to virulence. | 1. different strains of trypanosoma lewisi represent different states of biological balance, especially between the powers of propagation and resistance to destruction. 2. the biological status of a given strain of trypanosoma lewisi is subject to cyclic variations as the result of immunological reactions in the blood of the host. 3. the factors limiting reproduction and causing destruction of trypanosoma lewisi in the blood are appreciably independent of each other. it is possible, therefore, t ... | 1915 | 19867877 |
| morphological and developmental anomalies of a pathogenic strain of trypanosoma lewisi and their relation to its virulence. | 1. the morphological and developmental anomalies of a pathogenic strain of trypanosoma lewisi have been described to show the unusual character of the strain. 2. especial attention is called to the spontaneous occurrence of ablepharoplastic forms of trypanosoma lewisi. 3. it is pointed out that morphological anomalies were most pronounced in infections that showed unusual conditions of multiplication, and that such infections usually proved severe. 4. finally, an appreciable correlation between ... | 1914 | 19867793 |
| a note on the pathogenicity of trypanosoma lewisi. | 1. some strains of trypanosoma lewisi may, at times, produce rapidly fatal infections in a large percentage of the rats infected. 2. in such strains of trypanosoma lewisi, a sufficient degree of pathogenicity may persist to warrant the designation of these strains as pathogenic. 3. the pathogenicity of a given strain of trypanosoma lewisi is not constant, but is subject to marked and even sudden variations. | 1914 | 19867780 |
| the occurrence and ultrastructure of trypanosoma (herpetosoma) lewisi (kent, 1880) laveran and mesnil, 1901, the parasite of rats (rattus norvegicus) in poland. | this study reports the light and electron microscopic examination of trypanosoma (herpetosoma) lewisi (kent, 1880) laveran and mesnil, 1901, isolated from rats (rattus norvegicus) from poland. bloodstream trypomastigotes were identified morphometrically from 100 specimens collected from three naturally infected rats rattus norvegicus. body length ranged from 15.45-23.64 microm and width from 1.3-2.32 microm while the free flagellum was 8.1 microm long. electron microscopic study of bloodstream t ... | 2009 | 19856842 |
| surprising variety in energy metabolism within trypanosomatidae. | the metabolism of trypanosomatidae differs significantly between distinct species and can even be completely different between various life-cycle stages of the same species. it has been proposed that differences in energy metabolism are related to differences in nutrient supply in the environments of the various trypanosomatids. however, the literature shows that availability of substrates does not dictate the type of energy metabolism of trypanosomatids, as trypanosoma theileri, trypanosoma lew ... | 2009 | 19748317 |
| [the immunosuppressant effect of t. lewisi (kinetoplastidae) infection on the multiplication of toxoplasma gondii (sarcocystidae) on alveolar and peritoneal macrophages of the white rat]. | the immunosuppressant effect of t. lewisi infection on the multiplication of t. gondii was compared in peritoneal (mp) and alveolar macrophages (ma) of white rat. two animal groups were infected with t. lewisi and sacrificed after four days and seven days post infection. a group without infection was maintained as a control. the number of intracellular parasites (tachyzoites) (it) was counted by light microscopy, calculating the rate infection rate per 100 total cells (tc) and per infected cells ... | 2009 | 19637684 |
| atypical human trypanosomiasis: a neglected disease or just an unlucky accident? | 2009 | 19162551 | |
| adult multiplication in trypanosoma lewisi. | 1947 | 18935409 | |
| liver changes in pantothenate-deficient rats infected with trypanosoma lewisi. | 1948 | 18898002 | |
| the influence of biotin deficiency on the course of infection with trypanosoma lewisi in the albino rat. | 1947 | 18895742 | |
| changes in the glucose metabolism of trypanosoma lewisi during the course of infection in the rat. | 1948 | 18869806 | |
| the oxidative metabolism of trypanosoma lewisi in a phosphate-saline medium. | 1948 | 18869805 | |
| a rare case of trypanosomiasis in a two month old infant in mumbai, india. | human trypanosomiasis is a rare occurrence in india. in the cases reported so far the disease causative species have been the species infective to animals viz., trypanosoma lewisi and trypanosoma evansi. these animal species usually non pathogenic in humans can acquire the desired virulence and emerge as human pathogens causing serious disease, in the right combination of environmental, host related and organism related factors. we report here a case of trypanosomiasis caused by the rodent paras ... | 2007 | 18338683 |
| course of trypanosoma lewisi infections in white rats treated with sodium salicylate. | 1949 | 18111990 | |
| rapid and sterilizing effect of penicillin sodium in experimental relapsing fever infections and its ineffectiveness in the treatment of trypanosomiasis (trypanosoma lewisi) and toxoplasmosis. | 1944 | 17844553 | |
| effect of age of infection upon the oxidative metabolism of trypanosoma lewisi. | 1947 | 17794150 | |
| alpha 2 macroglobulin activity in rats infected with typanosoma lewisi and treated with cyclophosphamide and its effect on the malignancy of the disease. | trypanosoma lewisi is a common, flagellated parasite of the rat. our previous study showed that rabbits injected with serum collected from rats infected with trypanosoma lewisi and treated with cyclophosphamide (cyi) produced high levels of antibodies against a new protein in the cyi rat serum. | 2007 | 17722867 |
| diagnosis of a trypanosoma lewisi-like (herpetosoma) infection in a sick infant from thailand. | trypanosomes were observed in a peripheral blood smear from a 45-day-old thai infant displaying fever, anaemia, cough and anorexia. human trypanosomiasis is not endemic to thailand, so parasite identification was undertaken to determine likely sources of the infection. several morphological parameters of the trypanosomes were similar to those of trypanosoma evansi and statistically different from those of trypanosoma lewisi-like parasites from a naturally infected indigenous rat. however, duplic ... | 2007 | 17644723 |
| infection by trypanosomes in marsupials and rodents associated with human dwellings in ecuador. | small mammals trapped in domestic and peridomestic environments of rural ecuador were screened for trypanosome infection by direct microscopy and hemoculture. identification of species of trypanosomes was then performed by morphological characteristics and by polymerase chain reaction (pcr) assays. of 194 animals collected, 15 were positive for infection (7.73%). eight (4.12%) were infected with trypanosoma cruzi (1 of 33 didelphis marsupialis; 7 of 61 rattus rattus). eleven r. rattus (18.03%) h ... | 2006 | 17304802 |
| trypanosoma cruzi oleate desaturase: molecular characterization and comparative analysis in other trypanosomatids. | trypanosoma cruzi lipids contain a high content of unsaturated fatty acids, primarily oleic acid (c18:1) and linoleic acid (c18:2). previous data suggest that this parasite is able to convert oleic acid into linoleic acid; humans are not able to do this. presently, we show that t. cruzi has a gene with high similarity to the delta12 (omega6)-oleate desaturase from plants. northern blot analysis of the oleate desaturase gene from t. cruzi (od(tc)) indicated that this gene is transcribed in epimas ... | 2006 | 17152952 |
| a gambian infant with fever and an unexpected blood film. | 2006 | 17002503 | |
| [trypanosomatidae of public health importance occurring in wild and synanthropic animals of rural venezuela]. | chagas disease and leishmaniasis are important public health problems due to their high frequency and broad distribution in latin america. understanding of the roles of reservoir animals is crucial for a global assessment of the epidemiology of these diseases. | 2006 | 16929902 |
| [the cases of infection of brown rats rattus norvegicus with trypanosoma lewisi (kent, 1880) laveran i mesnil, 1901, in the area of warsaw agglomeration]. | two from three brown rats (rattus norvegicus) catched in milan6wek near warsaw, and one catched in the centre of warsaw were infected with trypanosoma lewisi. the morphometric features of trypanosomes were in accordance with the features of t. lewisi gived by other authors. this is first note about infection of free living rats with t. lewisi in poland. | 2001 | 16894750 |
| pathological developments mediated by cyclophosphamide in rats infected with trypanosoma lewisi. | trypanosoma lewisi is an obligatory, flagellated parasite of the rat. despite the fact that naturally the rats overcome the disease, a lethal infection can be induced by the administration of an immunosuppressive agent, i.e. cyclophosphamide (cy). in the cy treated infected rats (cyi) the severity of the trypanosome infection was demonstrated in the internal organs, in the following order: lungs>liver>heart>spleen>kidney. the parasites were not detected in the brain. the accumulation of the para ... | 2006 | 16859956 |
| the inhibition of nucleic acid and protein synthesis in trypanosoma lewisi by the antibody ablastin. | 1960 | 16590665 | |
| variation and inheritance in size in trypanosoma lewisi: ii. the effects of growing "pure lines" in different vertebrate and invertebrate hosts and a study of size and variation in infections occurring in nature. | 1921 | 16586829 | |
| variation and inheritance in size in trypanosoma lewisi: 1. life-cycle in the rat and a study of size and variation in "pure line" infections. | 1921 | 16586822 | |
| a study of the interaction of host and parasite: a reaction product in infections with trypanosoma lewisi which inhibits the reproduction of the trypanosomes. | 1924 | 16576770 | |
| trypanosoma lewisi-induced immunosuppression: the effects on alveolar macrophage activities against cryptococcus neoformans. | the immunosuppressive effect of trypanosoma lewisi infection on alveolar macrophage (am) activities against cryptococcus neoformans was studied in an animal model. two groups of rats were treated with t. lewisi and killed after 4 (4d-rats) and 7 days (7d-rats), respectively. a third group not given t. lewisi, served as control. am were challenged in vitro with c. neoformans. phagocytosis was assessed with a fluorescence method. superoxide anion production was evaluated with the nitroblue tetrazo ... | 2006 | 16546172 |
| a rare case of human trypanosomiasis caused by trypanosoma evansi. | human trypanosoma infections like the ones seen in africa and south america are unknown in india. the only exception in literature is of two documented cases of a self-limiting febrile illness, being attributed to trypanosoma lewisi like parasites. we are reporting an unusual case of trypanosomiasis from the rural parts of chandrapur district in maharashtra. an adult male farmhand who used to practice veterinary medicine also, presented with history of febrile episodes on and off since five mont ... | 2006 | 16505565 |
| phylogeny, taxonomy and grouping of trypanosoma rangeli isolates from man, triatomines and sylvatic mammals from widespread geographical origin based on ssu and its ribosomal sequences. | phylogenetic relationships among trypanosoma rangeli isolates from man, wild mammals and triatomine bugs from widespread geographical origin were inferred by comparison of the small subunit of ribosomal gene sequences. the phylogenetic trees indicated that the subgenus herpetosoma is polyphyletic and strongly supported division of this group into two monophyletic lineages, one made up of t. rangeli, t. rangeli-like and allied species and other consisting of t. lewisi and related taxa. based on p ... | 2004 | 15552400 |
| concerning salicylate inhibition of ablastic activity in trypanosoma lewisi infection. | 1951 | 14908771 | |
| studies on the metabolism of the protozoa. i. metabolism of the parasitic flagellate, trypanosoma lewisi. | 1951 | 14886348 | |
| antagonism of spirillum minus infection in rats towards trypanosoma lewisi and t. equinum. | 1951 | 14863953 | |
| [incidence of trypanosoma lewisi, sarcocystis muris, species of spirochaeta, and larvae of microfilaria in the rats of panama city and its suburbs]. | 1951 | 14858447 | |
| on the reciprocal interference between the growth of yoshida sarcoma and that of trypanosoma lewisi. | 1950 | 14802575 | |
| persistent infection of mongolian jirds with a non-pathogenic trypanosome, trypanosoma (herpetosoma) grosi. | non-pathogenic trypanosomes of the subgenus herpetosoma are normally host specific, and laboratory models include trypanosoma lewisi in rats and trypanosoma musculi in mice. two isolates of trypanosoma grosi, originating from apodemus agrarius and apodemus peninsulae, grew well in mongolian jirds, meriones unguiculatus, after intraperitoneal inoculation of 2 x 10(5) or a minimum 500 bloodstream forms. the course of t. grosi infection in jirds resembled t. musculi infection in mice, rather than t ... | 2003 | 14636022 |
| a study of cytoplasmic inclusions in trypanosoma lewisi and their relationship to the formation of antibody. | 1959 | 14429094 | |
| observations on changes in trypanosoma lewisi after growth in calorically restricted and in normal mice. | 1959 | 14417031 | |
| antigenic relationships among trypanosoma lewisi--complex cells. i. agglutinins in antisera. | 1965 | 14342129 | |
| effect of bacterial endotoxin on trypanosoma lewisi infections in rats. | 1965 | 14339383 | |
| oxygen uptake by trypanosoma lewisi complex cells--i. l isolate. | 1965 | 14314982 | |
| effect of x-irradiation on trypanosoma lewisi infection in the rat. | 1965 | 14281214 | |
| synthesis of unsaturated fatty acids in the slime mold physarum polycephalum and the zooflagellates leishmania tarentolae, trypanosoma lewisi, and crithidia sp.: a comparative study. | 1965 | 14280472 | |
| ultrastructure of trypanosoma lewisi. | 1964 | 14244808 | |
| changes in lactic dehydrogenase levels of trypanosoma lewisi associated with appearance of ablastic immunity. | 1964 | 14213222 | |
| incidence of trypanosoma lewisi in puerto rican bats. | 1962 | 13894373 | |
| in vitro studies of ablastin, the reproduction-inhibiting antibody to trypanosoma lewisi. | 1962 | 13882937 | |
| effect of salicylates and related compounds on ablastic response in rats infected with trypanosoma lewisi. ii. dihydroxybenzoic acids; antagonisms. | 1961 | 13866324 | |
| depression of parasitemia in trypanosoma lewisi infection of rats injected with 6-mercaptopurine. | 1962 | 13863072 | |
| serial passage of trypanosoma lewisi in the heterologous mouse host. ii. developmental history during transfer in adequately-fed hosts. | 1960 | 13762224 | |
| quantitative studies on heterologous sera inducing development of trypanosoma lewisi in mice. | 1961 | 13762223 | |
| in vitro phagocytosis of trypanosoma lewisi by rat exudative cells. | 1960 | 13758793 |