Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| characterization of leaf transcriptome in banksia hookeriana. | banksia is a significant element in vegetation of southwestern australia, a biodiversity hotspot with global significance. in particular, banksia hookeriana represents a species with significant economic and ecological importance in the region. for better conservation and management, we reported an overview of transcriptome of b. hookeriana using rna-seq and de novo assembly. we have generated a total of 202.7 million reads (18.91 billion of nucleotides) from four leaf samples in four plants of ... | 2017 | 28161492 |
| irritant and sensitizing potential of some common indian cact' succulents, lichens and aquatic plants. | irritant potential of 3 cacti, opuntia dilenii, rhispalis baccifera and cereus peruvians, and 4 succulents, euphorbia royleana, euphorbia antiquorum,sansevieria zeyilanica and agave sisalana was tested by rubbing their freshly exposed pulp 10 times on the forearm skin of 10 human voluntrees. opuntia dilenii, euphorbia antiquorum, rhispalis baccifera and agave sisalana produced transitory itching and burning or dermatitis in only one patient each, indicating that these plants are not highly irrit ... | 2017 | 28150662 |
| the fate of the herbicide propanil in plants of the littoral zone of the three gorges reservoir (tgr), china. | the anti-seasonal hydrology with 30m water fluctuations in the three gorges reservoir (tgr) of china attracts growing environmental and ecological concerns. we investigated the biotransformation of the herbicide propanil in plants dominating in the littoral zone of the tgr by applying the (14)c-ring-labeled herbicide into non-aseptic hydroponic plant systems (cynodon dactylon, nelumbo nucifera and bidens pilosa), aseptic plants (lemna minor and lemna gibba) and cell suspension cultures (c. dacty ... | 2016 | 27745669 |
| cloning and characterization of the ubc gene from lotus (nelumbo nucifera). | protein ubiquitination is extensively involved in the regulation of a considerable number of physiological processes in plant cells. e2 (ubiquitin-conjugating enzyme, ubc), one of the essential enzymes of eukaryotic ubiquitination, catalyzes protein ubiquitination together with e1 and e3. in this study, we cloned four full-length cdna nnubcs of nelumbo nucifera. with the same coding sequence length of 459 bp and coding 153 amino acids, these four genes are highly homologous with the atubc1 and a ... | 2016 | 27525889 |
| enhanced microbial, functional and sensory properties of herbal yogurt fermented with korean traditional plant extracts. | this study evaluated the effects of two korean traditional plant extracts (diospyros kaki thunb. leaf; dk, and nelumbo nucifera leaf; nn) on the fermentation, functional and sensory properties of herbal yogurts. compared to control fermentation, all plant extracts increased acidification rate and reduced the time to complete fermentation (ph 4.5). supplementation of plant extracts and storage time were found to influence the characteristics of the yogurts, contributing to increased viability of ... | 2016 | 27499669 |
| nelumbo nucifera gaertn leaves extract inhibits the angiogenesis and metastasis of breast cancer cells by downregulation connective tissue growth factor (ctgf) mediated pi3k/akt/erk signaling. | nelumbo nucifera gaertn (nymphaeaceae) has been recognized as a medicinal plant, which was distributed throughout the asia. the aqueous extract of nelumbo nucifera leaves extract (nle) has various biologically active components such as polyphenols, flavonoids, oligomeric procyanidines. however, the role of nle in breast cancer therapy is poorly understood. | 2016 | 27178635 |
| quantitative ethnomedicinal survey of medicinal plants given for cardiometabolic diseases by the non-institutionally trained siddha practitioners of tiruvallur district, tamil nadu, india. | the burden of cardiometabolic diseases such as dyslipidemia, hyperglycemia, hypertension, visceral obesity and atherosclerotic cardiovascular diseases and the use of traditional medicine for the management of such diseases are high in india; hence there is a need to document and analyze such therapies. | 2016 | 27090346 |
| interaction studies of greenly synthesized gold nanoparticles with bovine serum albumin (bsa) using fluorescence spectroscopy. | in the present study, gold nanoparticles (aunps) with an average particle size of -41.23 nm were synthesized using eco-friendly reducing material (i.e., aqueous nelumbo nucifera root extract). rapid reduction results in the formation of polydispersed nanoparticles. the formation of aunps was characterized by surface plasmon resonance (spr) which was determined by uv-vis spectra (band at 544 nm), ftir, sem-edx, tem, hr-tem, and xrd. this study aims to investigate the interaction between aunps and ... | 2015 | 26682387 |
| anti-aging potential of phytoextract loaded-pharmaceutical creams for human skin cell longetivity. | the exposure to ultraviolet radiations (uvr) is the key source of skin sunburn; it may produce harmful entities, reactive oxygen species (ros), leading to aging. the skin can be treated and protected from the injurious effects of ros by using various pharmaceutical formulations, such as cream. cream can be loaded with antioxidants to quench ros leading to photo-protective effects. moreover, modern medicines depend on ethnobotanicals for protection or treatment of human diseases. this review arti ... | 2015 | 26448818 |
| anti-obesity effects of the mixture of eriobotrya japonica and nelumbo nucifera in adipocytes and high-fat diet-induced obese mice. | the present study is to evaluate the anti-obesity effects of eriobotrya japonica (ej), nelumbo nucifera (nn), and their mixture (mix, 1:1 ratio) in 3t3-l1 adipocytes and high-fat diet-induced obese mice. the treatment of ej, nn, and mix in 3t3-l1 adipocytes effectively inhibited lipid accumulation, significantly decreased expression of peroxisome proliferator-activated receptor gamma (pparγ), sterol regulatory element binding protein (srebp1c), and adipocyte lipid-binding protein (ap2), and sign ... | 2015 | 26133751 |
| cloning and expression of an apetala1-like gene from nelumbo nucifera. | the objective of this study was to clone the full-length cdna of the apetala1 (ap1) gene from lotus and analyze its sequence and expression pattern. the full-length cdna sequence of the nnap1 gene was amplified from the petals of nelumbo nucifera 'hongxia' using rt-pcr and rapid amplification of cdna ends. bioinformatic methods were used to analyze the sequence characteristics of the gene. quantitative real-time pcr methods were used to investigate the expression pattern of nnap1 in various orga ... | 2015 | 26125889 |
| the role of bio-inspired hierarchical structures in wetting. | superhydrophobicity facilitates the development of self-cleaning, anti-biofouling, and anti-corrosion surfaces. the leaves of the lotus (nelumbo nucifera) and taro (colocasia esculenta) plants are well known for their self-cleaning properties. a hierarchical structure comprising papillae epidermal cells superimposed with epicuticular wax crystalloids of varying shapes, sizes, and orientations is an important aspect of the surface of these plant leaves. we fabricated two types of hierarchical str ... | 2015 | 25856043 |
| effects of the four-herb compound anbp on wound healing promotion in diabetic mice. | wound healing is a troublesome problem in diabetic patients. besides, there is also an increased risk of postsurgical wound complications for diabetic patient. it has been revealed that traditional chinese medicine may promote healing and inhibit scar formation, while the changes of morphology and physiology of wounds on such medicine treatment still remain elusive. in this study, we first used the ultralow temperature preparation method to produce mixed superfine powder from agrimonia pilosa (a ... | 2015 | 25795279 |
| anti-angiogenic effect of nelumbo nucifera leaf extracts in human umbilical vein endothelial cells with antioxidant potential. | nelumbo nucifera gaertn (nymphaeaceae) has long been used as a traditional herb in chinese, japanese, indian, and korean medicinal practices since prehistoric times and flourishes today as the primary form of medicine. this study reports for the first time the potent ability of n. nucifera leaf extracts to inhibit vascular endothelial growth factor (vegf)-induced angiogenesis in vitro and in vivo, as well as their antioxidant efficacy in various scavenging models and an analysis of their chemica ... | 2015 | 25714482 |
| barcoding melting curve analysis for rapid, sensitive, and discriminating authentication of saffron (crocus sativus l.) from its adulterants. | saffron (crocus sativus l.) is one of the most important and expensive medicinal spice products in the world. because of its high market value and premium price, saffron is often adulterated through the incorporation of other materials, such as carthamus tinctorius l. and calendula officinalis l. flowers, hemerocallis l. petals, daucus carota l. fleshy root, curcuma longa l. rhizomes, zea may l., and nelumbo nucifera gaertn. stigmas. to develop a straightforward, nonsequencing method for rapid, ... | 2014 | 25548775 |
| green synthesized silver nanoparticles using nelumbonucifera root extract for efficient protein binding, antioxidant and cytotoxicity activities. | silver nanoparticles (agnps) with a mean particle size of ∼ 16.7 nm were synthesized using an eco-friendly reducing material, aqueous nelumbo nucifera root extract. rapid reduction resulted in the formation of polydispersed nanoparticles. the formation of agnps was characterized by surface plasmon resonance, which was determined by ultraviolet-visible (uv-vis) spectroscopy (band at 412 nm), fourier transform infrared spectroscopy, scanning electron microscopy-energy dispersive x-ray spectroscopy ... | 2014 | 25463656 |
| antimicrobial efficacy of punica granatum mesocarp, nelumbo nucifera leaf, psidium guajava leaf and coffea canephora extract on common oral pathogens: an in-vitro study. | alternative therapies are increasingly being explored as extensive use of synthetic chemicals has led to the emergence of substantial side effects. phytomedicine has been well practiced as traditional medicine in various cultures for treatment of oral diseases. it has gained importance of late as an alternative to the conventional therapy. various plant and fruit extracts have been monitored recently to assess their potential against the common oral pathogens. aim of this study was to assess in- ... | 2014 | 25177642 |
| useful ethnophytomedicinal recipes of angiosperms used against diabetes in south east asian countries (india, pakistan & sri lanka). | this paper is based on data recorded from various literatures pertaining to ethnophytomedicinal recipes used against diabetes in south east asia (india, pakistan and srilanka). traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. in total 419 useful phytorecipes of 270 plant species belonging to 74 angiospermic families were collected. from the review it was revealed that plants showing hypoglycemic potential mainly belong to the families, cucurb ... | 2014 | 25176368 |
| integrated syntenic and phylogenomic analyses reveal an ancient genome duplication in monocots. | unraveling widespread polyploidy events throughout plant evolution is a necessity for inferring the impacts of whole-genome duplication (wgd) on speciation, functional innovations, and to guide identification of true orthologs in divergent taxa. here, we employed an integrated syntenic and phylogenomic analyses to reveal an ancient wgd that shaped the genomes of all commelinid monocots, including grasses, bromeliads, bananas (musa acuminata), ginger, palms, and other plants of fundamental, agric ... | 2014 | 25082857 |
| molecular evolution and functional characterisation of an ancient phenylalanine ammonia-lyase gene (nnpal1) from nelumbo nucifera: novel insight into the evolution of the pal family in angiosperms. | phenylalanine ammonia-lyase (pal; e.c.4.3.1.5) is a key enzyme of the phenylpropanoid pathway in plant development, and it catalyses the deamination of phenylalanine to trans-cinnamic acid, leading to the production of secondary metabolites. this enzyme has been identified in many organisms, ranging from prokaryotes to higher plants. because nelumbo nucifera is a basal dicot rich in many secondary metabolites, it is a suitable candidate for research on the phenylpropanoid pathway. | 2014 | 24884360 |
| cloning a glutathione peroxidase gene from nelumbo nucifera and enhanced salt tolerance by overexpressing in rice. | a full-length cdna clone encoding an 866 bp-length glutathione peroxidase protein (nngpx) was isolated from lotus (nelumbo nucifera l.). the deduced amino acid sequence of the nngpx gene had significant homology with atgpx6. a 3d structural model of the nngpx was constructed by homology modeling. the cloned nngpx gene was expressed in escherichia coli, and a fusion protein of about 40 kda was detected after isopropyl thiogalactoside induction. under different concentrations of na2seo3 treatments ... | 2014 | 24715609 |
| phosphorus removal from domestic wastewater by nelumbo nucifera gaertn. and cyperus alternifolius l. | domestic wastewater is a source of phosphorus contamination that causes eutrophication when it contaminates aquatic environments. nelumbo nucifera gaertn. and cyperus alternifolius l. were applied for phosphorus removal from domestic wastewater. from the study, phosphorus in domestic wastewater was removed from the initial concentration of 1.038 ± 0.001 mgl(-1) to 0.094 ± 0.001 and 0.048 ± 0.004 mgl(-1) by n. nucifera and c. alternifolius, respectively, within 5 days. in addition, total kjeldahl ... | 2014 | 24603027 |
| anthelmintic activities of aporphine from nelumbo nucifera gaertn. cv. rosa-plena against hymenolepis nana. | nelumbo nucifera gaertn. cv. rosa-plena (nelumbonaceae), commonly known as lotus, is a perennial aquatic plant grown and consumed throughout asia. all parts of n. nucifera have been used for various medicinal purposes in oriental medicine. from the leaves of nelumbo nucifera gaertn. cv. rosa-plena (an aquatic plant), liriodenine (1), lysicamine (2), (-)-anonaine (3), (-)-asimilobine (4), (-)-caaverine (5), (-)-n-methylasimilobine (6), (-)-nuciferine (7), (-)-nornuciferine (8), (-)-roemerine (9), ... | 2014 | 24583851 |
| evaluation of in vitro aldose reductase inhibitory potential of alkaloidal fractions of piper nigrum, murraya koenigii, argemone mexicana, and nelumbo nucifera. | aldose reductase is primarily involved in development of long-term diabetic complications due to increased polyol pathway activity. the synthetic aldose reductase inhibitors are not very successful clinically. therefore, the natural sources may be exploited for safer and effective aldose reductase inhibitors. | 2014 | 24127538 |
| protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice. | the effects of neferine, a bisbenzylisoquinline alkaloid extracted from the chinese traditional medicine seed embryo of nelumbo nucifera gaertn, on amiodarone-induced pulmonary fibrosis in mice were evaluated. adult kunming mice were induced to develop pulmonary fibrosis through intratracheal instillation of amiodarone (6.25 mg/kg) on the 1st, 3rd and 5th day. mice were treated orally with saline, neferine (20 mg/kg), prednisolone (15 mg/kg), pirfenidone (100 mg/kg) twice a day after the third a ... | 2013 | 23792144 |
| neferine isolated from nelumbo nucifera enhances anti-cancer activities in hep3b cells: molecular mechanisms of cell cycle arrest, er stress induced apoptosis and anti-angiogenic response. | hepatocellular carcinoma (hcc) is one of the most aggressive malignant diseases and is highly resistant to conventional chemotherapy. neferine, a major bisbenzylisoquinoline alkaloid derived from the embryos of nelumbo nucifera, has been reported a few physiological activities. however, the mechanisms of anticancer effects are not well understood and its detailed activities on hep3b cells have not been determined. our results suggest that neferine exhibited cytotoxicity against hcc hep3b cells, ... | 2013 | 23746959 |
| [the application of cation exchange resins in the separation of total flavonoids and alkaloids from seed embryo of nelumbo nucifera]. | to explore the optimal separation condition of the total flavonoids and alkaloids from seed embryo of nelumbo nucifera. | 2012 | 23627099 |
| isolation and functional characterization of a salt responsive transcriptional factor, lrbzip from lotus root (nelumbo nucifera gaertn). | basic leucine zipper transcription factor (bzip) is involved in signaling transduction for various stress responses. here we reported a bzip transcription factor (accession: jx887153) isolated from a salt-resistant lotus root using cdna-aflp approach with rt-pcr and race-pcr method. full-length cdna which consisted of a single open reading frame encoded a putative polypeptide of 488 amino acids. on the basis of 78, 76, and 75 % sequence similarity with the bzips from medicago truncatula (xp_0035 ... | 2013 | 23288562 |
| characterization of chemical composition of bee pollen in china. | bee pollen has been praised for its good nutrition and therapeutic values. china is the largest producer in the world. twelve common varieties of monofloral bee pollen collected from china's main producing regions were selected for nutritional composition analysis, including proximate contents, dietary fibers, amino acid distribution, fatty acid composition, and mineral elements. the proximate compositions mostly met the specifications regulating pollen load quality of china. proline and glutami ... | 2013 | 23265625 |
| application of microdialysis for elucidating the existing form of hyperoside in rat brain: comparison between intragastric and intraperitoneal administration. | hypericum perforatum (st. john's wort) is an important anti-depressant herb used in clinic and commonly prescribed for mild depression. hyperoside is one of the major components of h. perforatum and is also detected in many plant species such as abelmoschus manihot, black currant, rosa agrestis, apocynum venetum and nelumbo nucifera. | 2012 | 23063958 |
| an evaluation of the inhibitory effects against rotavirus infection of edible plant extracts. | rotaviruses are the single most important cause of severe diarrhea in young children worldwide. the developments of specific, potent and accessible antiviral treatments that restrain rotavirus infection remain important to control rotavirus disease. | 2012 | 22834653 |
| natural products: a safest approach for obesity. | obesity is recognized as a social problem, associated with serious health risks and increased mortality. numerous trials have been conducted to find and develop new anti-obesity drugs through herbal sources to minimize adverse reactions associated with the present anti-obesity drugs. the use of natural products as medicine has been documented for hundreds of years in various traditional systems of medicines throughout the world. this review focuses on the medicinal plants such as achyranthus asp ... | 2012 | 22821661 |
| [screening of pancreatic lipase and alpha-glucosidase inhibitors from chinese dietary herbs]. | the present study was conducted to develop new inhibitors of pancreatic lipase and alpha-glucosidase from chinese dietary herbs. sixty-three dietary herbs from 39 taxonomic families were selected and extracted with aqueous ethanol or water. the extracts were then tested with in vitro enzyme assays for their ability to inhibit pancreatic lipase and alpha-glucosidase activities. orlistat and acarbose were used as two positive controls. the extracts of nelumbo nucifera, curcuma longa, piper longum ... | 2012 | 22803384 |
| biodiversity and importance of floating weeds of dara ismail, khan district of kpk, pakistan. | the present paper is based on the results of taxonomic research work conducted in dera ismail khan district of kpk, pakistan, during 2005 - 2007. the area was extensively surveyed in order to collect floating aquatic weeds. from the study area 11 floating aquatic weed species belonging to 9 genera and 9 families were collected and identified in the light of available literature. these plants include bryophytes: 1 species, ricciocarpus natans (l.) corda; pteridophytes: 2 species, azolla pinnata r ... | 2011 | 22754062 |
| neferine, an alkaloid ingredient in lotus seed embryo, inhibits proliferation of human osteosarcoma cells by promoting p38 mapk-mediated p21 stabilization. | identification of natural products that have antitumor activity is invaluable to the chemoprevention and therapy of cancer. the embryos of lotus (nelumbo nucifera) seeds are consumed in beverage in some parts of the world for their presumed health-benefiting effects. in this report we studied the effects of neferine, a major alkaloid component in lotus embryos, on human osteosarcoma cells and the underlying mechanisms. we found that neferine possessed a potent growth-inhibitory effect on human o ... | 2011 | 22227330 |
| heterologous expression of a nelumbo nucifera phytochelatin synthase gene enhances cadmium tolerance in arabidopsis thaliana. | phytochelatin synthase (pcs) is a key enzyme involved in the synthesis of phytochelatins, which are thought to play important roles in heavy metal detoxification. the sacred lotus (nelumbo nucifera), one of the most popular ornamental species, has been shown to be a potential phytoremediator of heavy metal polluted water. however, the phytochelatin synthase gene in n. nucifera has not been identified yet. here, we report the isolation and function characterization of a n. nucifera homologue of p ... | 2012 | 22161260 |
| polyphenolic extract of lotus root (edible rhizome of nelumbo nucifera) alleviates hepatic steatosis in obese diabetic db/db mice. | nonalcoholic fatty liver disease (nafld) is emerging as the most common liver disease of industrialized countries. thus, discovering food components that can ameliorate nafld is of interest. lotus root, the edible rhizome of nelumbo nucifera, contains high levels of polyphenolic compounds, and several health-promoting properties of lotus root have been reported. in this study, we tested whether feeding a polyphenolic extract of lotus root to db/db mice protects them from hepatic steatosis. | 2011 | 22067945 |
| larvicidal and repellent activity of medicinal plant extracts from eastern ghats of south india against malaria and filariasis vectors. | to evaluate the larvicidal and repellent activities of ethyl acetate and methanol extracts of acacia concinna (a. concinna), cassia siamea (c. siamea), coriandrum sativum (c. sativum),cuminum cyminum (c. cyminum), lantana camara (l. camara), nelumbo nucifera (n. nucifera) phyllanthus amarus (p. amarus), piper nigrum (p. nigrum) and trachyspermum ammi (t. ammi) against anopheles stephensi (an. stephensi) and culex quinquefasciatus (cx. quinquefasciatus). | 2011 | 21967692 |
| Documentation and determination of consensus about phytotherapeutic veterinary practices among the Tharu tribal community of Uttar Pradesh, India. | PURPOSE: The aim of the present investigation was to document the phytotherapeutic knowledge and veterinary healthcare management practices among the Tharu tribal community of Uttar Pradesh, India and to determine the consensus of such practices, in order to evaluate the potential for new veterinary drugs of herbal origin. METHODS: This study was conducted in 2000-2004 using semistructured, open-ended questionnaires, informal interviews and group discussions with farmers engaged in animal husban ... | 2011 | 21927989 |
| Efficacy of adulticidal and larvicidal properties of botanical extracts against Haemaphysalis bispinosa, Hippobosca maculata, and Anopheles subpictus. | The aim of the present study was to investigate the adulticidal and larvicidal activity of dried leaf hexane, ethyl acetate, acetone, and methanol extracts of Nelumbo nucifera, Manilkara zapota, Ipomoea staphylina, and Acalypha indica against the adults of Haemaphysalis bispinosa (Acarina: Ixodidae), hematophagous fly Hippobosca maculata (Diptera: Hippoboscidae), and fourth instar larvae of malaria vector Anopheles subpictus (Diptera: Culicidae). Parasites were exposed to varying concentrations ... | 2011 | 21861064 |
| Simultaneous determination of liensinine, isoliensinine and neferine from seed embryo of Nelumbo nucifera Gaertn. in rat plasma by a rapid HPLC method and its application to a pharmacokinetic study. | A rapid and specific HPLC method has been developed and validated for the simultaneous determination of liensinine (CAS 2586-96-1), isoliensinine (CAS 6817-41-0) and neferine (CAS 2292-16-2) in rat plasma. The sample was prepared by a liquid-liquid extraction with diethyl ether and the recovery was above 80% from the plasma for the three compounds. Chromatographic separation was achieved with a Hypersil BDS C18 column (4.0 mm x 250 mm, particle size 5 microm). A mobile phase consisting of methan ... | 2011 | 21827045 |
| nanostructure on taro leaves resists fouling by colloids and bacteria under submerged conditions. | the antifouling and self-cleaning properties of plants such as nelumbo nucifera (lotus) and colocasia esculenta (taro) have been attributed to the superhydrophobicity resulting from the hierarchical surface structure of the leaf and the air trapped between the nanosized epicuticular wax crystals. the reported study showed that the nanostructures on the taro leaf surfaces were also highly resistant to particle and bacterial adhesion under completely wetted conditions. adhesion force measurements ... | 2011 | 21736298 |
| effects of neferine on the pharmacokinetics of amiodarone in rats. | amiodarone, an iodinated benzofuran derivative with predominantly class iii anti-arrhythmic effects, is used to treat supraventricular and ventricular arrhythmias. the purpose of this study was to assess the potential of neferine, an effective anti-pulmonary fibrosis drug isolated from the embryo of nelumbo nucifera gaertner's seeds, to alter the pharmacokinetic profile of amiodarone. experimental sprague-dawley rats were randomly divided into two groups. in groups 1 and 2, amiodarone was given ... | 2011 | 21728182 |
| perchlorate in soybean sprouts (glycine max l. merr.), water dropwort (oenanthe stolonifera dc.), and lotus (nelumbo nucifera gaertn.) root in south korea. | the occurrence of perchlorate in soybean sprouts (glycine max l. merr), water dropwort (oenanthe stolonifera dc.), and lotus (nelumbo nucifera gaertn.) root, which are commonly consumed by people in south korea, was determined by using an ion chromatograph coupled with a tandem mass spectrometer. for soybean sprouts (11 samples), perchlorate was detected in most (91%) of the samples at various concentrations of up to 78.4 μg/kg dry weight (dw); the mean concentration was 35.2 μg/kg dw. for water ... | 2011 | 21627073 |
| protective effect of neferine on endothelial cell nitric oxide production induced by lysophosphatidylcholine: the role of the ddah-adma pathway. | neferine, extracted from the seed embryo of nelumbo nucifera gaertn., has multiple cardiovascular pharmacological effects. the dimethylarginine dimethylaminohydrolase (ddah) - asymmetric dimethylarginine (adma) system is a novel pathway for modulating nitric oxide (no) production. the aim of this study was to investigate whether the protective effect of neferine on endothelial no production was related to the ddah-adma pathway. human umbilical vein endothelial cells (huvecs) were first exposed t ... | 2011 | 21526974 |
| screening of traditional chinese medicinal plants for quorum-sensing inhibitors activity. | the misuse of antibiotics has contributed to widespread development of antimicrobial resistance among clinically significant bacterial species. alternative approaches other than those using antibiotics are needed in the fight against infectious diseases. quorum sensing (qs) is an intercellular signaling and gene regulatory mechanism, which is used by a number of opportunistic pathogenic bacteria in determining virulence gene expression. the study of qs may yield another strategy for disease cont ... | 2011 | 21439518 |
| detoxifying effect of nelumbo nucifera and aegle marmelos on hematological parameters of common carp (cyprinus carpio l.). | the objective of this study was to investigate the efficacy of nelumbo nucifera and aegle marmelos on common carp exposed to sub-lethal concentrations of combined heavy metals (5 ppm) under laboratory conditions. the fish were treated with nelumbo nucifera (500 mg/kg bwt) and aegle marmelos (500 mg/kgbwt) for 30 days as a dietary supplement. the blood biochemical parameters of the fish were evaluated by analyzing the level of red blood cells (rbc), packed cell volume (pcv), hemoglobin concentrat ... | 2010 | 21331178 |
| acute and subchronic oral toxicity studies of nelumbo nucifera stamens extract in rats. | since the use of nelumbo nucifera stamens in herbal medicines as well as in cosmetic products are highly prevalent in thailand and increasing worldwide, acute and subchronic toxicity studies to confirm the safe use of nelumbo nucifera stamens are warranted. | 2011 | 21291992 |
| extract of lotus leaf ( nelumbo nucifera ) and its active constituent catechin with insulin secretagogue activity. | the effect of lotus leaf ( nelumbo nucifera gaertn.) on diabetes is unclear. we hypothesized that lotus leaf can regulate insulin secretion and blood glucose levels. the in vitro and in vivo effects of lotus leaf methanolic extract (nne) on insulin secretion and hyperglycemia were investigated. nne increased insulin secretion from β cells (hit-t15) and human islets. nne enhanced the intracellular calcium levels in β cells. nne could also enhance phosphorylation of extracellular signal-regulated ... | 2011 | 21235242 |
| immunoregulatory and anti-hiv-1 enzyme activities of antioxidant components from lotus (nelumbo nucifera gaertn) rhizome. | in this study, two anti-oxidant micromolecular components ( l2f-2, l2f-3), and an antioxidant macromolecular component lb2, were extracted from lotus (nelumbo nucifera gaertn) rhizomes. mass spectrum (ms), fourier transform infrared spectroscopy (ftir) and nuclear magnetic resonance (nmr) were used to identify these compounds. l2f-2 was (+/-)-gallocatechin, l2f-3 was (-)-catechin and lb2 was a polysaccharide-protein complex with a molecular weight of 18.8 kda. lb2 was identified as a polysacchar ... | 2010 | 21114474 |
| effects of nelumbo nucifera rhizome extract on cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus in a scopolamine-induced amnesia animal model. | a large aquatic herb, nelumbo nucifera gaertn, has psychopharmacological effects similar to minor tranquillizers and antistress agents. this study examined the effects of nelumbo nucifera rhizome extracts (nre) on cell proliferation and neuroblast differentiation in the hippocampal dentate gyrus (dg) of a rat model of scopolamine-induced amnesia. immunohistochemical markers included ki67, an endogenous marker for active cell cycle, and doublecortin (dcx), a marker for immature neurons and migrat ... | 2010 | 21086545 |
| rapid validated hptlc method for estimation of betulinic acid in nelumbo nucifera (nymphaeaceae) rhizome extract. | betulinic acid (pentacyclic triterpenoid) is an important marker component present in nelumbo nucifera gaertn. rhizome. n. nucifera rhizome has several medicinal uses including hypoglycaemic, antidiarrhoeal, antimicrobial, diuretic, antipyretic, psychopharmacological activities. | 2010 | 21043041 |
| synthesis of silver nanoparticles using nelumbo nucifera leaf extract and its larvicidal activity against malaria and filariasis vectors. | the aim of this study was to investigate the larvicidal potential of the hexane, chloroform, ethyl acetate, acetone, methanol, and aqueous leaf extracts of nelumbo nucifera gaertn. (nymphaeaceae) and synthesized silver nanoparticles using aqueous leaf extract against fourth instar larvae of anopheles subpictus grassi and culex quinquefasciatus say (diptera: culicidae). nanoparticles are being used in many commercial applications. it was found that aqueous silver ions can be reduced by aqueous ex ... | 2011 | 20978795 |
| neferine inhibits cultured hepatic stellate cell activation and facilitates apoptosis: a possible molecular mechanism. | neferine is a major alkaloid component of "lian zi xin", embryos of the seeds of nelumbo nucifera gaertner, nymphaeaceae. previous studies have shown that neferine has an inhibitory effect on pulmonary fibrosis through its anti-inflammatory and anti-oxidative activities and inhibition of cytokines and nf-κb. however, it is unknown whether neferine also has an inhibitory effect on liver fibrosis through inhibition of tgf-β1 and collagen i and facilitation of apoptosis of hepatic stellate cells. t ... | 2010 | 20969858 |
| oxidative and color stability of cooked ground pork containing lotus leaf (nelumbo nucifera) and barley leaf (hordeum vulgare) powder during refrigerated storage. | this study aimed to evaluate the oxidative and color stability of cooked ground pork containing lotus leaf powder at 0.1 (lp1) and 0.5% (lp2) as well as barley leaf powder at 0.1 (bp1) and 0.5% (bp2) during refrigerated storage for 10 days. the oxidative stability of these powders was compared with butylhydroxytoluene (bht). lp1 had higher a* and lower b* values than the control (-) over 4 days (p<0.05). the ph values of the ground pork samples made with addition of lp and bht decreased until da ... | 2011 | 20926202 |
| antioxidant activity of bovine and porcine meat treated with extracts from edible lotus (nelumbo nucifera) rhizome knot and leaf. | lotus (nelumbo nucifera) is an extensively cultivated vegetable in eastern asia, particularly in china. both lotus rhizome knot (lrk) and lotus leaf (ll) are waste products of the lotus industry. extracts from lrk and ll are proposed as antioxidants for meat. porcine and bovine ground meat samples were subjected to three treatments: control (with no additives), lrk (lotus rhizomes knot extract 3% w/w), and ll (lotus leaf extract 3% w/w). raw and cooked samples were stored at 4°c and the antioxid ... | 2010 | 20869815 |
| regulation of the 5-ht3a receptor-mediated current by alkyl 4-hydroxybenzoates isolated from the seeds of nelumbo nucifera. | four known alkyl 4-hydroxybenzoates, i.e., methyl 4-hydroxybenzoate (1), ethyl 4-hydroxybenzoate (2), propyl 4-hydroxybenzoate (3), and butyl 4-hydroxybenzoate (4), were isolated from the seeds of nelumbo nucifera gaertner (nymphaeaceae) for the first time. the structures of the isolates were identified by 1d- and 2d-nmr spectroscopy and comparison with published values. the compounds were evaluated for their effects on the 5-ht-stimulated inward current (i(5-ht)) mediated by the human 5-ht(3)a ... | 2010 | 20860031 |
| whole body radioprotective activity of an acetone-water extract from the seedpod of nelumbo nucifera gaertn. seedpod. | procyanidins extracted with acetone-water from lotus (nelumbo nucifera gaertn.) seedpod (lspcs) were evaluated for in vivo radioprotective activity against whole body gamma irradiation in swiss albino mice. pretreated with lspcs 200 mg/kg by intragastric (i.g.) for 15 days was found to be the most effective dose in preventing radiation sickness, reducing radiation-induced mortality, increasing mean survival time and elevating radiation median lethal dose (ld(50)) from 8.9 to 10.5 gy, indicating ... | 2010 | 20837084 |
| antiobesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in rats fed a high fat diet. | lotus (nelumbo nucifera) leaf has been used to treat obesity. the purpose of this study was to investigate the antiobesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in high fat diet-induced obese rats. | 2010 | 20804619 |
| antioxidant and hepatic protective effects of lotus root hot water extract with taurine supplementation in rats fed a high fat diet. | nelumbo nucifera, known as sacred lotus, is a well-known medicinal plant and this lotus root is commonly used as food compared to different parts of this plant. this study was conducted to investigate the antioxidant and hepatic protective effects of lotus root hot water extract with taurine supplementation in high fat diet-induced obese rats. | 2010 | 20804615 |
| anti-amnesic activity of neferine with antioxidant and anti-inflammatory capacities, as well as inhibition of ches and bace1. | the multifunctional potential of neferine derived from the embryo of nelumbo nucifera seeds for the age-related neurodegenerative disorders, in vivo anti-amnesic activities and in vitro cholinesterases (ches)- and β-site app cleaving enzyme 1 (bace1)-inhibitory activities, as well as anti-inflammatory and antioxidant activities were investigated. | 2010 | 20736023 |
| lotus leaf extract and l-carnitine influence different processes during the adipocyte life cycle. | abstract: | 2010 | 20687953 |
| in-vitro and in-vivo evaluations of cytochrome p450 1a2 interactions with nuciferine. | the effects of nuciferine, a major active aporphine alkaloid from the leaves of nelumbo nucifera gaertn, on a cytochrome p450 1a2 (cyp1a2) probe substrate were investigated in vitro and in vivo. | 2010 | 20609070 |
| (s)-armepavine from chinese medicine improves experimental autoimmune crescentic glomerulonephritis. | intra-renal t cells and macrophages play a key pathogenic role in the development and progression of glomerular crescents. we aimed to establish (s)-armepavine [(s)-arm], a major bioactive compound of a chinese medicinal plant, nelumbo nucifera, as a potential therapeutic agent in the treatment of autoimmune crescentic glomerulonephritis (acgn). | 2010 | 20551296 |
| improvement in high-fat diet-induced obesity and body fat accumulation by a nelumbo nucifera leaf flavonoid-rich extract in mice. | diets high in fat lead to excessive lipid accumulation in adipose tissue, which is a crucial factor in the development of obesity, hepatitis, and hyperlipidemia. in this study, we investigated the antiobesity effect of a flavonoid-enriched extract from nelumbo nucifera leaf (nlfe) in vivo. c57bl/6 mice were fed with a high-fat diet (hfd) to induce obesity. nlfe reduced the body weight, body lipid accumulation, and activities of fatty acid synthase (fas), glutamic oxaloacetic transaminase, and gl ... | 2010 | 20481471 |
| remediation of cadmium contaminated irrigation and drinking water: a large scale approach. | cadmium is one of the most troublesome toxic heavy metals. it accumulates in the water reservoirs and agricultural soil as a result of intensive use of cd contaminated phosphate fertilizers, e.g. in agriculture in the north central province (ncp) of sri lanka. the hyper-accumulator thlaspi caerulescens, accumulates up to 1000 ppm cd in shoots without exhibiting toxicity symptoms. the storage rhizomes of year old nelumbo nucifera (lotus) natural vegetation in water reservoirs in ncp accumulated 2 ... | 2010 | 20466045 |
| antidepressant-like effects of neferine in the forced swimming test involve the serotonin1a (5-ht1a) receptor in mice. | the effects of neferine, an alkaloid of nelumbo nucifera gaertner embryos, on immobility in the forced swimming test, which is used to evaluate antidepressants, were investigated in mice. the administration of neferine from 25 to 100 mg/kg i.p. elicited anti-immobility effects in mice. the molecular dose effects of neferine in the forced swimming test were almost equal to those of the typical antidepressants maprotiline and imipramine. the involvement of the 5-ht receptor subtypes was also studi ... | 2010 | 20176013 |
| evaluation of hypoglycemic activity of inorganic constituents in nelumbo nucifera seeds on streptozotocin-induced diabetes in rats. | the seeds of nelumbo nucifera (lotus) have been used in the traditional system of medicine for various ailments including diabetes. the present study was aimed at analyzing the levels of biologically important trace elements in the lotus seeds by atomic absorption spectroscopy and evaluating the hypoglycemic properties of seed ash on streptozotocin-induced diabetes in rats. diabetic rats treated with lotus seed ash at a concentration of 200 mg/kg body weight orally for 30 days exhibited signific ... | 2010 | 20165930 |
| selective cholinesterase inhibitory activities of a new monoterpene diglycoside and other constituents from nelumbo nucifera stamens. | a new beta-cyclogeraniol diglycoside (5), along with four known components, cycloartenol (1), p-hydroxybenzoic acid (2), vanilloloside (3), and 5'-o-methyladenosine (4), were first isolated from the n-buoh fraction of nelumbo nucifera stamens. the chemical structure of 5 was elucidated as 1-hydroxymethyl-2,6,6-trimethyl-1-cyclohexene 9-o-beta-d-glucopyranosyl-(1-->6)-beta-d-glucopyranoside (nuciferoside) on the basis of chemical and spectroscopic evidence, including 1d, 2d nmr, and ms. the anti- ... | 2010 | 20118551 |
| antimutagenicity of some flowers grown in thailand. | the mutagenicity of dichloromethane, methanol and water extracts of antigonon leptopus hook. & arn., curcuma sessilis gage, hibiscus rosa-sinensis linn., ixora coccinea linn., millingtonia hortensis linn., nelumbo nucifera gaertn., plumeria obtusa linn., punica granatum linn., rhinacanthus nasutus ((linn.) kurz.) and syzygium malaccense ((linn.) merr.& perry) before and after nitrite treatment was firstly investigated in the ames test. their antimutagenicity against the product of the reaction m ... | 2010 | 20100534 |
| exploring the potential of nelumbo nucifera rhizome on membrane stabilization, mast cell protection, nitric oxide synthesis, and expression of costimulatory molecules. | immunomodulatory activity of nelumbo nucifera rhizome was evaluated for its standardized extract (nnre) with respect to betulinic acid. various key parameters including erythrocyte membrane stabilization, inhibition of histamine release, reduction in nitric oxide production and depletion of expression of costimulatory molecules of macrophages were estimated. the result displayed that nnre stabilized erythrocyte membrane significantly at 10 (42.05%) and 100 microg/ml (44.31%). although considerin ... | 2010 | 20095810 |
| immunomodulatory potential of rhizome and seed extracts of nelumbo nucifera gaertn. | nelumbo nucifera gaertn. (nymphaeaceae) is a well-known aquatic plant which has been used for the treatment of several disorders including skin disease, cough, inflammation, fever and many other disorders. | 2010 | 20079418 |
| attenuation of acute and chronic restraint stress-induced perturbations in experimental animals by nelumbo nucifera gaertn. | aqueous extract of leaves of nelumbo nucifera was investigated on acute stress (immobilization stress)-induced biochemical alterations in swiss mice. the animals were also subjected to acute physical stress (swimming endurance test) and acute chemical stress (writhing test) to gauge the antistress potential of the extract. further to evaluate the antistress activity of nelumbo nucifera in chronic stress condition, fresh wistar rats were subjected to cold restraint stress (4 degrees for 1 h) for ... | 2008 | 20046740 |
| sh21b, an anti-obesity herbal composition, inhibits fat accumulation in 3t3-l1 adipocytes and high fat diet-induced obese mice through the modulation of the adipogenesis pathway. | sh21b is an anti-obesity composition composed of seven herbs: scutellaria baicalensis georgi, prunus armeniaca maxim, ephedra sinica stapf, acorus gramineus soland, typha orientalis presl, polygala tenuifolia willd and nelumbo nucifera gaertner. it has been used for the treatment of obesity in traditional medical clinics in korea, but its anti-obesity effects and mechanism of action have not been studied until now. | 2010 | 19963057 |
| comparative analysis of essential oil components and antioxidant activity of extracts of nelumbo nucifera from various areas of china. | this study was designed to examine the composition of extracts and essential oil components from nelumbo nucifera leaves from the principal habitats in china. the amounts of phenolics, flavonoids, and proanthocyanidins in the lotus leaf extracts varied widely, ranging from 354 to 487 mg/g gallic acid equivalents, from 172 to 236 mg/g rutin equivalents, and from 124 to 179 mg/g catechin equivalents, respectively. all of the extracts had strong antioxidant activity in comparison to the standard co ... | 2010 | 19919095 |
| bioactive compounds and antioxidant and antiproliferative activities of korean white lotus cultivars. | in traditional korean medicine, lotus (nelumbo nucifera gaertn) roots have been used as an antidiabetic and an antiproliferative remedy. however, scientific publications on lotus properties are very limited. therefore, it was decided to investigate the korean white lotus cultivars in order to find out their bioactivity. it was found that all lotus cultivars (inchisa, muan, garam, and chungyang) possess high amounts of bioactive compounds: total phenols, between 7.95 +/- 0.8 and 4.21 +/- 0.3 mg o ... | 2009 | 19857070 |
| extract from the leaf of nucifera reduced the development of atherosclerosis via inhibition of vascular smooth muscle cell proliferation and migration. | nelumbo nucifera gaertn, a perennial aquatic plant, has been used as a medicinal herb in china and india. we have previously reported that consumption of nucifera leaf extract (nle) reduced the development of atherosclerosis in cholesterol-fed rabbits; however, the molecular mechanisms involved were unclear. atherosclerotic plaque is generated partly by proliferation and migration of vascular smooth muscle cells (vsmc). herein, we demonstrated that vsmc treated with nle-triggered apoptosis and a ... | 2010 | 19799955 |
| inhibitory effects of armepavine against hepatic fibrosis in rats. | activation of hepatic stellate cells (hscs) plays a crucial role in liver fibrogenesis. armepavine (arm, c19h23o3n), an active compound from nelumbo nucifera, has been shown to exert immunosuppressive effects on t lymphocytes and on lupus nephritic mice. the aim of this study was to investigate whether arm could exert anti-hepatic fibrogenic effects in vitro and in vivo. a cell line of rat hscs (hsc-t6) was stimulated with tumor necrosis factor-alpha (tnf-alpha) or lipopolysaccharide (lps) to ev ... | 2009 | 19723340 |
| antioxidative effect and active components from leaves of lotus ( nelumbo nucifera ). | the dpph scavenging effect, the inhibition of human low-density lipoprotein oxidation, and antioxidative contents were employed for the activity-guided purification to identify the antioxidant components of lotus leaves (leaves of nelumbo nucifera gaertn.). the methanolic extract of lotus leaves (llm) was separated into ethyl acetate (llme), n-butanol (llmb), and water (llmw) fractions. llme and llmb exhibited greater capacity to scavenge dpph radical, delayed ldl oxidation, and had higher antio ... | 2009 | 19572539 |
| neferine enhances insulin sensitivity in insulin resistant rats. | neferine was isolated from green seed embryo of nelumbo nucifera gaertn which has been used as an anti-obesity agent in traditional chinese herbal medicine. | 2009 | 19527823 |
| nelumbo nucifera semen extract improves memory in rats with scopolamine-induced amnesia through the induction of choline acetyltransferase expression. | nelumbo nucifera semen (nns) is a traditional herb with anti-diarrheal, anti-ganacratia, and tranquilizer-like pharmacological activities. in this study, we examined the anti-amnesic effect of nns on rats with scopolamine-induced amnesia. passive avoidance tests, acetylcholinesterase (ache) activity, and choline acetyltransferase (chat) expression were used to evaluate the nns anti-amnesic effects. the rats were divided into five groups: the normal group, scopolamine-treated group (1mg/kg; contr ... | 2009 | 19463889 |
| blockade of herg k+ channel by isoquinoline alkaloid neferine in the stable transfected hek293 cells. | we studied the effects of isoquinoline alkaloid neferine (nef) extracted from the seed embryo of nelumbo nucifera gaertn on human ether-à-go-go-related gene (herg) channels stably expressed in human embryonic kidney (hek293) cells using whole-cell patch clamp technique, western blot analysis and immunofluorescence experiment. nef induced a concentration-dependent decrease in current amplitude according to the voltage steps and tail currents of herg with an ic(50) of 7.419 microm (n(h) -0.5563). ... | 2009 | 19424681 |
| kaempferol isolated from nelumbo nucifera stamens negatively regulates fcepsilonri expression in human basophilic ku812f cells. | mast cells and basophils perform important functions as pivotal effector cells in ige-mediated allergic reactions. ku812f cells, a human basophilic cell line isolated originally from chronic myelocytic leukemia, express a high affinity receptor of ige, fcepsilonri. kaempferol was extracted and isolated from a methanolic extract of flavonoid-rich nelumbo nucifera stamens. in the present study, the inhibitory effects of kaempferol on fcepsilonri expression in human basophilic ku812f cells was exam ... | 2009 | 19307764 |
| the sacred lotus (nelumbo nucifera) - phytochemical and therapeutic profile. | nelumbo nucifera gaertn. (nymphaeaceae), also known as sacred lotus, is a well known medicinal plant. this article reviews the traditional uses, phytochemistry and therapeutic reports on different parts of n. nucifera viz. the seeds, rhizomes, leaves and flowers. this review also describes various compounds isolated from different parts of this plant and the therapeutic benefits derived from those phytoconstituents. | 2009 | 19298686 |
| simultaneous determination of quercetin and its glycosides from the leaves of nelumbo nucifera by reversed-phase high-performance liquid chromatography. | the purpose of this study was to develop reversed-phase hplc method for the simultaneous determination of the flavonoids from the leaves of nelumbo nucifera, which have been known to exhibit antioxidant, anti-hiv, antihyperlipidemic and antiobesity effects. hplc separation was achieved on c(18) column using gradient elution with mobile phase consisting of acetonitrile-water containing 0.1% formic acid. the separated peaks were identified by electrospray ionization mass spectrometry. the hplc met ... | 2009 | 19280149 |
| molecular cloning and expression analysis of an mn-sod gene from nelumbo nucifera. | a rapid amplification cdna end (race) assay was established to achieve the complete sequence of mitochondrial manganese-superoxide dismutase (mn-sod) cdna in nelumbo nucifera. the obtained full-length cdna of mn-sod was 926 bp and contained a 699-bp open reading frame encoding an mn-sod precursor of 233 amino acids. the recombinant of mn-sod expressed by pet-32a vector in escherichia coli bl21 was confirmed by sodium dodecyl sulfate polyacrylamide gel electrophoresis and western blotting assays. ... | 2009 | 19018482 |
| effects of extracts and neferine from the embryo of nelumbo nucifera seeds on the central nervous system. | the effects of embryos of the seeds of nelumbo nucifera on the central nervous system were studied in mice. meoh extracts of embryos of nelumbo nucifera seeds significantly inhibited locomotor activity in mice. the meoh extract was successively partitioned between h(2)o and n-hexane, between h(2)o and chcl(3), and between h(2)o and n-buoh. chcl(3) extracts strongly inhibited locomotor activity in mice, although other extracts had no effect on locomotor activity. the main alkaloid of chcl(3) extr ... | 2008 | 19010651 |
| inhibitory effects of nelumbo nucifera leaves on rat lens aldose reductase, advanced glycation endproducts formation, and oxidative stress. | the preventive and therapeutic potency against oxidative stress and diabetic complications of nelumbo nucifera were evaluated via the 1,1-diphenyl-2-picrylhydrazyl (dpph), trolox equivalent antioxidant capacity (teac), and total reactive oxygen species (ros) assays, as well as the rat lens aldose reductase (rlar) and advanced glycation endproducts (age) assays. the leaf extract of n. nucifera exerted potent antioxidant effects as well as marked inhibitory effects for rlar and age formation, corr ... | 2008 | 18952135 |
| changes in extreme high-temperature tolerance and activities of antioxidant enzymes of sacred lotus seeds. | sacred lotus (nelumbo nucifera gaertn. 'tielian') seed is long-lived and extremely tolerant of high temperature. water content of lotus and maize seeds was 0.103 and 0.129 g h2o [g dw](-1), respectively. water content, germination percentage and fresh weight of seedlings produced by surviving seeds gradually decreased with increasing treatment time at 100 degrees c. germination percentage of maize (zea mays l. 'huangbaogu') seeds was zero after they were treated at 100 degrees c for 15 min and t ... | 2008 | 18726532 |
| novel effects of nelumbo nucifera rhizome extract on memory and neurogenesis in the dentate gyrus of the rat hippocampus. | memory enhancement is a matter of concern in general, and in particular to people suffering from cognitive dysfunction. in this study, we investigated the effect of nelumbo nucifera rhizome extract on learning and memory function. a step-through passive avoidance test was performed with wistar rats. in addition, immunohistochemistry was used to investigate cell proliferation and differentiation in the dentate gyrus of the hippocampus. the methanol extract of n. nucifera rhizome (mnr) resulted in ... | 2008 | 18638527 |
| [inhibitory effects of liquor cultured with nelumbo nucifera and nymphaea tetragona on the growth of microcystis aeruginosa]. | the inhibitory effects of liquor cultured with nelumbo nucifera and nymphaea tetragona on the growth of microcystis aeruginosa have been investigated by measuring the cell number and the chlorophyll a content of microcystis aeruginosa of culture in the laboratory. the results showed that the inhibitory effects on the growth of microcystis aeruginosa with different concentration of the liquor cultured with nelumbo nucifera and nymphaea tetragona were dissimilar, and an evident phenomenon appeared ... | 2007 | 18268975 |
| chronic renal failure among farm families in cascade irrigation systems in sri lanka associated with elevated dietary cadmium levels in rice and freshwater fish (tilapia). | chronic renal failure (crf), in the main agricultural region under reservoir based cascade irrigation in sri lanka has reached crisis proportion. over 5,000 patients in the region are under treatment for crf. the objective of this study is to establish the etiology of the crf. concentrations of nine heavy metals were determined in sediments, soils of reservoir peripheries, water and nelumbo nucifera (lotus) grown in five major reservoirs that supply irrigation water. all five reservoirs carried ... | 2008 | 18200439 |
| effects of plant extract neferine on cyclic adenosine monophosphate and cyclic guanosine monophosphate levels in rabbit corpus cavernosum in vitro. | to further investigate the relaxation mechanism of neferine (nef), a bis-benzylisoquinoline alkaloid extracted (isolated) from the green seed embryo of nelumbo nucifera gaertn in china, on rabbit corpus cavernosum tissue in vitro. | 2008 | 18097520 |
| constituents from the leaves of nelumbo nucifera stimulate lipolysis in the white adipose tissue of mice. | nelumbo nucifera gaertn. (nymphaceae) has been used for various medicinal purposes as in chinese herbal medicine. in particular, the leaves are known for diuretic and astringent properties, and are used to treat obesity. during our search for a plant-derived anti-obesity agent from natural products, we have found that a 50% ethanol (etoh) extract prepared from the leaves of n. nucifera (nn) stimulated lipolysis in the white adipose tissue (wat) of mice and that the beta-adrenergic receptor (beta ... | 2007 | 17893829 |
| screening of indian medicinal plants for acetylcholinesterase inhibitory activity. | the cholinergic hypothesis of alzheimer's disease (ad) has provided the rationale for the current pharmaco-therapy of this disease, in an attempt to reduce the cognitive decline caused by cholinergic deficits. nevertheless, the search for potent and long-acting acetylcholinesterase (ache) inhibitors that exert minimal side effects in ad patients is still ongoing. ache inhibitors are currently the only approved therapy for the treatment of alzheimer's disease; only a limited number of drugs are c ... | 2007 | 17639556 |
| [pcr, clone and sequence analysis of rdna-its of nelumbo nucifera from different geographical origins in china]. | to provide dna molecular marker for identification of nelumbo nucifera by exploring the differences of nrdna-its sequence of n. nucifera originated from different habitats. | 2007 | 17608215 |
| [molecular identity of crocus sativus and its misused substitutes by its sequence]. | to find the patterns of the rdna its sequence variation of crocus sativus, chrysanthemum chanetii, nelumbo nucifera, zea mays and garthamus tinctorius and to establish the molecular biological method for the identification of c. sativus and the others. | 2007 | 17608214 |
| (s)-armepavine inhibits human peripheral blood mononuclear cell activation by regulating itk and plcgamma activation in a pi-3k-dependent manner. | chinese herbs are useful edible and medicinal plants for their immune modulatory functions. we have proven that (s)-armepavine (c19h23o3n; mw313) from nelumbo nucifera inhibits the proliferation of human pbmcs activated with pha and improves autoimmune diseases in mrl/mpj-lpr/lpr mice. in the present study, the pharmacological activities of (s)-armepavine were evaluated in pha-activated pbmcs. the results showed that (s)-armepavine suppressed pha-induced pbmc proliferation and genes expression o ... | 2007 | 17284681 |
| down-regulation of inos and tnf-alpha expression by kaempferol via nf-kappab inactivation in aged rat gingival tissues. | the primary objective of this study was to evaluate the ability and mechanism of action of kaempferol, which is contained in extracts from nelumbo nucifera, a well-known oriental herb used in traditional medicine, with regard to the inhibition of inos and tnf-alpha expression in aged rat gingival tissues. we conducted an investigation into the age-related effects of kaempferol on reactive oxygen species (ros) and gsh oxidative status in samples of aged gingival tissues. western blotting was cond ... | 2007 | 17278014 |
| rat lens aldose reductase inhibitory constituents of nelumbo nucifera stamens. | aldose reductase, the principal enzyme of the polyol pathway, has been shown to play an important role in the complications associated with diabetes. a methanol extract of the stamens of nelumbo nucifera gaertn. was shown to exert an inhibitory effect on rat lens aldose reductase (rlar), and thus was fractionated using several organic solvents, including dichloromethane, ethyl acetate and n-butanol. the ethyl acetate-soluble fraction, which manifested potent rlar-inhibitory properties, was then ... | 2006 | 16881021 |