Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| black-pigmented anaerobic bacteria associated with ovine periodontitis. | periodontitis is a polymicrobial infectious disease that causes occlusion change, tooth loss, difficulty in rumination, and premature culling of animals. this study aimed to detect species of the genera porphyromonas and prevotella present in the periodontal pocket of sheep with lesions deeper than 5mm (n=14) and in the gingival sulcus of animals considered periodontally healthy (n=20). the presence of microorganisms was evaluated by polymerase chain reaction (pcr) using specific primers for por ... | 2017 | 28619155 |
| effect of 2-hydroxy-4-methylthio-butanoic acid on ruminal fermentation, bacterial distribution, digestibility, and performance of lactating dairy cows. | the objective of this experiment was to test the effect of a met analog, 2-hydroxy-4-methylthio-butanoic acid (hmtba), on ruminal fermentation and microbial protein synthesis, nutrient digestibility, urinary n losses, and performance of dairy cows. eight multiparous lactating holstein dairy cows were assigned to 4 levels of hmtba [0 (control), 0.05, 0.10, and 0.15% (dry matter basis)] in a replicated 4×4 latin square trial. experimental periods were 28 d, including 21 d for adaptation. ruminal a ... | 2015 | 25434334 |
| bacteremic skin and soft tissue infection caused by prevotella loescheii. | anaerobes are a major component of gut flora. they play an important role in the pathogenesis of infections resulting from breaches in mucus membranes. because of the difficulties in cultivating and identifying it, their role continues to be undermined. the purpose of this paper is to report a case of prevotella loescheii bacteremic skin and soft tissue infection and review the literature. | 2014 | 24661318 |
| smoking-related cotinine levels and host responses in chronic periodontitis. | smoking has been reported to increase the risk of periodontal disease by disrupting the balance of immune responses and tissue repair processes; however, this risk varies among smokers. cotinine levels in saliva are routinely used to measure the level of smoking, and reflect the quantity of nicotine, and other smoking-related xenobiotics that challenge host systems. this study delineated characteristics of inflammatory mediators in saliva and serum antibody responses to both periodontal pathogen ... | 2013 | 24283398 |
| sterility testing of apheresis hematopoietic progenitor cell products using an automated blood culture system. | aabb standards require monitoring of hematopoietic progenitor cell (hpc) products for microbial contamination. to date, there is no automated blood culture system cleared by the food and drug administration for this application. our objective was to validate the versatrek system (trek diagnostic systems) for sterility testing of apheresis hpc products. | 2013 | 23438051 |
| septic arthritis of the knee due to prevotella loescheii following tooth extraction. | this is a case report of septic arthritis of the knee due to prevotella loescheii, in a patient with advanced arthrosis. two weeks beforehand he had undergone a dental root extraction without antibiotic prophylaxis. his knee had become inflamed 48 hours after extraction and he was started on ibuprofen and steroid treatment (prescribed by his primary health care doctor). with a provisional diagnosis of septic arthritis, synovial fluid was taken for study. antimicrobial therapy was commenced with ... | 2008 | 18667985 |
| proteinase activity of prevotella species associated with oral purulent infection. | prevotella intermedia and prevotella nigrescens are often regarded as principal causes of acute dentoalveolar infection; however, other species within the genus are also known to be associated with such infection. the aim of this study was to determine the in vitro proteolytic activity of these different prevotella species that have been implicated with dentoalveolar infection. a total of 234 strains were obtained from pus specimens from dentoalveolar infection and from the plaque of healthy vol ... | 2006 | 16586023 |
| antimicrobial resistance and beta-lactamase production of clinical isolates of prevotella and porphyromonas species. | this study determined the beta-lactamase production and the antimicrobial resistance of 72 prevotella species and 48 porphyromonas species isolated from different clinical specimens. | 2005 | 15722627 |
| prevotella shahii sp. nov. and prevotella salivae sp. nov., isolated from the human oral cavity. | two bacterial strains, ehs11(t) and epsa11(t), which were isolated from the human oral cavity, were characterized in terms of phenotypic and biochemical characteristics, cellular fatty acid profiles and phylogenetic position based on 16s rrna gene sequence analysis. 16s rrna gene sequence analysis showed that each of the isolates belonged to a novel species of the genus prevotella. strain ehs11(t) was related to prevotella loescheii (about 95 % similarity), whereas strain epsa11(t) was related t ... | 2004 | 15143039 |
| infection of a total hip arthroplasty with prevotella loeschii. | infection is a serious complication of total hip replacement. it has been proposed that 6% of all infections after total hip arthroplasty may be of dental origin through hematogenous spread. however, no conclusive evidence that the mouth is a definitive source for infection of a total hip replacement has been reported. in the current case, prevotella loeschii, a pigmented bacteroides species was identified in a total hip replacement. prevotella loeschii is an organism which exclusively inhabits ... | 2004 | 15043121 |
| [outbreak of tropical phagedenic ulcers after the rainy season in dijibouti]. | the incidence of cutaneous ulcers was observed after the rainy season in djibouti in 1997. based on the study of epidemiologic, clinical, biological, and therapeutic features these lesion were classified as phagedenic ulcers. while direct examination showed numerous fusiform bacilli, cultures performed in one patient, led to isolation of numerous colonies of prevotella loescheii. though less common, two other anaerobic bacterial species were detected, i.e., peptostreptococcus anaerobius and pept ... | 2003 | 12910663 |
| antimicrobial activity of magainin analogues against anaerobic oral pathogens. | magainins are a family of potent antimicrobial cationic peptides that possess antimicrobial activity against a wide range of target organisms. in this study, the antimicrobial activity of synthetic magainin-mimetic compounds msi-751 and msi-774 was investigated against the periodontal pathogens porphyromonas gingivalis, fusobacterium nucleatum, actinobacillus actinomycetemcomitans, eikenella corrodens, prevotella loescheii and prevotella intermedia. p. gingivalis was more susceptible to msi-751 ... | 2003 | 12507842 |
| [clinical and bacteriological features of six cases with intracranial abscess in childhood]. | from october 1988 to march 2001, 5 patients with 6 episodes of intracranial abscesses were admitted to chiba-children's hospital. average age when they were admitted was 10 years and 1 month. initial clinical symptoms were fever in 5 cases, and headache in 1 case. it took 21 days from the appearance of the initial symptoms to diagnose the intracranial abscess. four out of 5 patients had underlying diseases that were prone to cause intracranial abscess. two patients of these were cyanotic congeni ... | 2002 | 11905002 |
| evaluation of the rapid id 32a system for identification of anaerobic gram-negative bacilli, excluding the bacteroides fragilis group. | objective: to evaluate the rapid id 32a system (biomérieux, marcy-l'etoile, france) for the identification of anaerobic gram-negative bacilli, excluding the bacteroides fragilis group. methods: five hundred and twenty-eight identified clinical isolates of non-b. fragilis group anaerobic gram-negative bacilli were tested in the rapid id 32a system, and identifications were compared with those obtained with conventional biochemical tests and gas-liquid chromatography. results: the rapid id 32a sys ... | 1999 | 11856276 |
| inhibitory effect of lactoperoxidase-generated hypothiocyanite upon black pigmented anaerobe growth. | this study aimed to evaluate the in vitro effect of lactoperoxidase with or without its substrates (hydrogen peroxide, thiocyanate) on the growth of 4 different black pigmented anaerobe (bpa) strains associated with the development and progress of periodontal diseases: porphyromonas gingivalis atcc 33277, prevotella intermedia nctc 9336, prevotella loescheii atcc 15930, and prevotella melaninogenica nctc 9338. a 5-min lactoperoxidase-generated oscn--hoscn incubation at ph 6.0, 7.0 or 8.0 resulte ... | 2001 | 11408950 |
| predominant cultivable subgingival microbiota of healthy and hiv-infected ethnic chinese. | although clinically distinctive types of periodontal disease are known to be associated with hiv infection, the pathogenesis remains unclear. in the present study, the subgingival microflora of 21 hiv-infected and 11 hiv-free ethnic chinese were studied using the direct microscopic and anaerobic culture methods. motile curved rods were found to be three times higher in the hiv-infected group under direct microscopy. otherwise, there were no significant differences between the diseased and health ... | 2001 | 11398993 |
| isolation and characterisation of dipeptidyl peptidase iv from prevotella loescheii atcc 15930. | a proline-specific dipeptidyl aminopeptidase, dipeptidyl peptidase iv (ec 3.4.14.5), was purified from a cell sonicate soluble fraction of prevotella loescheii atcc 15930 by sequential column chromatography. the molecular mass of the native enzyme was estimated as 160 kda by high-pressure liquid gel filtration column chromatography and unheated sodium dodecyl sulphate-polyacrylamide gel electrophoresis (sds-page). the subunit molecular mass was 80 kda when the enzyme was heated to 100 degrees c ... | 2001 | 11389867 |
| subdural empyema caused by prevotella loescheii with reduced susceptibility to metronidazole. | 2001 | 11222578 | |
| profile of subgingival microbiota in children with mixed dentition. | a diversity of microbial species has been detected in children's oral flora at an early age. to investigate the composition of the subgingival microbiota of different groups of teeth in children with mixed dentition, 40 systemically healthy children, aged 7-8 years, randomly chosen, were examined. subgingival plaque samples were taken from the mesiobuccal sites of 21, 41, 16 and 36 permanent teeth and 53, 73, 64 and 84 deciduous teeth. the samples were cultured for bacterial isolation anaerobica ... | 2000 | 11155173 |
| cloning, characterization, and possible origin of the prevotella loescheii dnak homolog. | heat shock proteins play an important role in bacterial survival and response to environmental stress. we cloned the prevotella loescheii hsp70 homolog (dnak) and characterized the coding sequence, regulatory regions, and evolutionary relationships to other bacteria. predicted proteins encoded by the p. loescheii dnak homolog (open reading frame orf-1) and two downstream coding regions, orf-2 and orf-3, are highly homologous to the proteins encoded by orf-4 (dnak), orf-5, and orf-6 from the dnak ... | 2001 | 11136127 |
| profile of subgingival microbiota in children with primary dentition. | eruption of primary teeth has a great influence on the oral environment by providing suitable niches for bacterial colonization. the aim of the study was to investigate the composition of the subgingival microbiota of primary incisors, canines and molars in 40 systemically healthy children aged 4-5 yr, chosen randomly. subgingival plaque samples were taken from the mesiobuccal sites of primary incisors (61, 81), canines (53, 73) and molars (64, 84). the samples were cultured for bacterial isolat ... | 2000 | 10791707 |
| mutant analysis of prevotella sp. plaa-lacz fusion protein expression in escherichia coli: support for an essential role of the stem-loop. | this study investigated the involvement of rna folding in the synthesis of a fusion protein with beta-galactosidase activity. the coding gap region of the prevotella loescheii adhesin gene plaa was fused in-frame with the escherichia coli lacz gene on plasmid psk105. n-terminal sequencing of the expressed plaa-lacz protein indicated that it resulted from translational initiation at a fortuitous ribosomal-binding site within the plaa sequence at nt 570. specific mutations were introduced in the s ... | 1999 | 10380648 |
| the importance of fimbriae in the virulence and ecology of some oral bacteria. | cumulative evidence indicates that bacterial adherence to mucosal and tooth surfaces as well as bacterial coaggregation are essential steps for colonization of various oral bacterial species. bacterial fimbriae have been shown to play an important role in the interaction between bacteria and host cells or among bacterial cells. the properties of fimbriae from selected species of oral bacteria are discussed in terms of virulence traits and ecological significance. among others, porphyromonas ging ... | 1998 | 10093527 |
| detection of dextranase-producing gram-negative oral bacteria. | thirty-one strains of 23 gram-negative oral bacterial species were examined for dextran-degrading activity on agar plates containing blue dextran. one strain each of capnocytophaga ochracea, capnocytophaga sputigena, prevotella loescheii, prevotella melaninogenica and prevotella oralis had detectable dextranase activity. the culture supernatants of p. melaninogenica and p. oralis cells contained dextranases of multiple sizes, but those of the other three species had a single size of enzyme. a 56 ... | 1998 | 9872116 |
| a hemagglutinating variant of prevotella melaninogenica isolated from the oral cavity. | strains resembling prevotella melaninogenica were isolated from healthy subjects and patients with periodontal disease and were identified using: a 5-test phenotypic screen; commercial identification kits; and a 16s rrna-based polymerase chain reaction (pcr) method. eleven clinical isolates closely resembling p. melaninogenica, and all from patients with periodontitis, were able to agglutinate erythrocytes. in the electron microscope, hemagglutinating isolates showed fimbria-like structures, tha ... | 1998 | 9872112 |
| the translational hop junction and the 5' transcriptional start site for the prevotella loescheii adhesin encoded by plaa. | the prevotella loescheii adhesin gene, plaa, contains a coding gap between a small open reading frame (orf-1) and a large open reading frame (orf-2). translation of the plaa mrna requires bypassing this 29-nt coding gap on the plaa transcript. we have determined the n-terminal peptide sequence of the so34 adhesin beyond the gap sequence. this sequence shows that the peptide junction between orf-1 and orf-2 is continuous in the adhesin and supports the conclusion that synthesis of the so34 adhesi ... | 1999 | 9841777 |
| serum antibodies reacting with subgingival species in refractory periodontitis subjects. | the purpose of this investigation was to compare the levels of serum igg antibody to 85 subgingival species in 32 refractory periodontitis, 56 successfully treated, and 33 periodontally healthy subjects. refractory subjects showed mean full mouth attachment loss and/or >3 sites showing attachment loss >2.5 mm within 1 year after 2 treatment modalities, scaling and root planing and surgery plus systemically administered tetracycline. successfully-treated subjects showed mean attachment level gain ... | 1998 | 9696261 |
| volatile fatty acid, metabolic by-product of periodontopathic bacteria, induces apoptosis in wehi 231 and raji b lymphoma cells and splenic b cells. | the ability of butyric acid, an extracellular metabolite from periodontopathic bacteria, to induce apoptosis in murine wehi 231 cells, splenic b cells, and human raji cells was examined. the culture filtrate of porphyromonas gingivalis, prevotella loescheii, and fusobacterium nucleatum, which contains high a percentage of butyric acid, induced dna fragmentation in wehi 231 cells. volatile fatty acid, especially butyric acid, significantly suppressed b-cell viability in a concentration-dependent ... | 1998 | 9596720 |
| fermentation product analysis in the identification of black-pigmented bacteria from periodontitis. | a quantitative procedure is described for the analysis of fermentation products of eight representative black-pigmented gram-negative anaerobic bacterial strains (porphyromonas gingivalis 381, porphyromonas gingivalis atcc 33277, prevotella intermedia atcc 25611, prevotella nigrescens atcc 33563, prevotella melaninogenica atcc 25845, prevotella denticola atcc 33185, and prevotella loescheii atcc 15930) from oral sites in humans, using gas-liquid chromatography. this procedure for the identificat ... | 1997 | 9345789 |
| beta-lactamase production by oral pigmented prevotella species isolated from young children. | the frequency of beta-lactamase production by oral pigmented prevotella species isolated from 23 healthy young children and the minimal inhibitory concentrations (mics) for 186 available beta-lactamase-positive isolates were examined by using the chromogenic cephalosporin disk test (ab biodisk, solna, sweden) and the etest (ab biodisk) and/or the agar dilution method of the national committee for clinical laboratory standards (villanova, pa, usa), respectively. beta-lactamase-positive prevotella ... | 1997 | 9310704 |
| beta-lactamase producing bacteria in adult periodontitis. | in 23 untreated adult periodontitis patients, the occurrence of beta-lactamase producing periodontal bacteria was determined. in addition to non-selective isolation media, selective isolation and growth of beta-lactamase positive subgingival bacterial species was carried out on blood agar plates supplemented with amoxicillin and plates with amoxicillin+clavulanic acid. porphyromonas gingivalis, prevotella intermedia, actinobacillus actinomycetemcomitans, peptostreptococcus micros, fusobacterium ... | 1997 | 9266340 |
| inhibition of prevotella and capnocytophaga immunoglobulin a1 proteases by human serum. | oral prevotella and capnocytophaga species, regularly isolated from periodontal pockets and associated with extraoral infections, secret specific immunoglobulin a1 (iga1) proteases cleaving human iga1 in the hinge region into intact fab and fc fragments. to investigate whether these enzymes are subject to inhibition in vivo in humans, we tested 34 sera from periodontally diseased and healthy individuals in an enzyme-linked immunosorbent assay for the presence and titers of inhibition of seven pr ... | 1997 | 9220164 |
| [a case of severe odontogenic infection with allergic skin reaction for beta-lactam antibiotics]. | a 54-aged woman consulted with right buccal phlegmon caused by lower apical periodontitis. the primary chemotherapy using flomoxef induced allergic skin eruption. a decision was made for using clindamycin, levofloxacin and fosfomycin as chemotherapeutic agents. cultured organisms from the abscess revealed the mixed infection with streptococcus sanguis, veillonella sp., prevotella loescheii, wolinella spp. on 12th hospital day, her serum crp turned to negative. this case carried numerous implicat ... | 1997 | 9209128 |
| an investigation into the use of sds-page of cell surface extracts and proteolytic activity to differentiate prevotella nigrescens and prevotella intermedia. | by comparison of the cell surface proteins derived from the outer membrane and fibrils from 14 prevotella intermedia and 19 prevotella nigrescens strains using sds and analysed by sds-page, it was possible to distinguish the two species. a polypeptide of approx. 21 kda distinguished p. intermedia strains, whereas two polypeptides of approx. 18 and 22 kda could be used to identify p. nigrescens strains. four other human oral black pigmented bacterial species (porphyromonas gingivalis, prevotella ... | 1996 | 8869494 |
| cell envelope and cell wall immunization of macaca fascicularis: effect on the progression of ligature-induced periodontitis. | the nonhuman primate, macaca fascicularis, was used to study the role of immunization with selected members of the periodontopathic microbiota in the longitudinal progression of ligature-induced periodontitis. animals were immunized with cell envelope antigens prepared from porphyromonas gingivalis and prevotella intermedia, and a mixture prepared from fusobacterium nucleatum, campylobacter rectus, and actinomyces viscosus. serum immunoglobulin g (igg), igm and iga isotype antibodies increased s ... | 1995 | 8602339 |
| coaggregation: specific adherence among human oral plaque bacteria. | nearly all human oral bacteria exhibit coaggregation, cell-to-cell recognition of genetically distinct cell types. clumps or coaggregates composed of the two kinds of cells are formed immediately upon mixing two partner cell types. members of all 18 genera tested exhibit lactose-reversible coaggregation. many of these interactions appear to be mediated by a lectin on one cell type that interacts with a complementary carbohydrate receptor on the other cell type. a lactose-sensitive adhesin has be ... | 1993 | 8462782 |
| expression of the prevotella loescheii adhesin gene (plaa) is mediated by a programmed frameshifting hop. | the 2.4-kb plaa gene, which encodes a prevotella loescheii galactoside-specific adhesin, contains a programmed frameshifting hop. the frameshift region consists of two uaa termination codons, two repeats of four identical bases between the terminators, and a stem-loop structure that has the potential to form a pseudoknot located downstream from the second uaa. the stem-loop and pseudoknot are features found in a number of retroviruses where frameshifting is a more common occurrence. the terminat ... | 1994 | 8144461 |
| the most frequently isolated gram-negative anaerobes in saliva and subgingival samples taken from young women. | stimulated saliva and a pooled subgingival sample from the first molars were collected from 30 caucasian women (mean age 30 years) for the presence of gram-negative anaerobic bacteria. the samples were inoculated on nonselective and selective media. the gram-negative anaerobic species occurring in the oral cavity of more than 50% of the subjects were selected for further analysis. fusobacterium nucleatum and prevotella melaninogenica were not recovered from subgingival sites without a simultaneo ... | 1994 | 8008430 |
| the oral gram-negative anaerobic microflora in young children: longitudinal changes from edentulous to dentate mouth. | eruption of primary teeth has a great influence on the oral environment by providing suitable niches for bacterial colonization. the composition of oral gram-negative anaerobic microflora was investigated in 21 young children (mean age 32 months) with primary dentition. the bacterial findings of samples were compared with those of the same children collected at their edentulous infant period (mean age 3 months). during the primary period, 2 samples were collected from each child: a sample with d ... | 1994 | 7936718 |
| adhesin degradation: a possible function for a prevotella loescheii protease? | prevotella loescheii pk1295 produces at least 3 proteases that are separable by isoelectric focusing. one of these proteases, an enzyme with an isoelectric point at 8.5 and an m(r) of 36,000, hydrolyzes the fimbria-associated adhesin on p. loescheii responsible for coaggregation with streptococcus oralis 34, as well as gelatin, casein and fibrin. the action of this protease may contribute to the detachment of p. loescheii from its streptococcal coaggregation partner and provide a mechanism for b ... | 1993 | 7903444 |
| volatile fatty acids, metabolic by-products of periodontopathic bacteria, inhibit lymphocyte proliferation and cytokine production. | short-chain fatty acids are a major by-product of anaerobic metabolism and can be detected in gingival fluid from periodontal pockets. since most t cells are present subjacent to the pocket epithelium in conjunction with the plasma cells, it is important to know how these t cells are affected by short-chain fatty acids produced by subgingival plaque. the purpose of this study is to examine the effects of extracellular metabolites from periodontopathic bacteria on the proliferation and cytokine p ... | 1995 | 7560387 |
| effect of periodontal treatments on serum igg antibody titers against periodontopathic bacteria. | serum igg antibody titers to 7 periodontopathic bacteria in periodontitis patients were measured at the 1st visit and after various periodontal treatments with clinically successful improvement, in order to evaluate what kind of factors are associated with changes of serum antibody titers. 20 patients (10 male and 10 female from 23 to 61 years old) with adult, rapidly progressive periodontitis were enrolled in this study. all patients received initial preparation and most of them also underwent ... | 1995 | 7560233 |
| the tet(q) gene in bacteria isolated from patients with refractory periodontal disease. | twenty-two tetracycline-resistant (tetr) anaerobic and facultative anaerobic bacteria isolated from periodontal pockets of 12 patients with refractory periodontitis were examined for the presence of the tet q determinant by dna-dna hybridization. dot blots of bacterial dna were tested with an intragenic digoxigenin-labelled tet(q) probe consisting of a 1.45 kb ecori/pvuii fragment from plasmid pnfd13-2. southern blots of chromosomal dna digested with the restriction enzyme ecori were also examin ... | 1994 | 7478767 |
| effect of proteolytic enzymes on the lysis and growth of oral bacteria. | previous studies have shown increased levels of proteolytic enzymes in affected periodontal sites. the aim of the present investigation was to evaluate the effect of proteolytic environments on the lysis and growth of selected oral bacteria associated with either healthy or diseased periodontal sites. the effect of trypsin, chymotrypsin and proteinase k on cell lysis was determined following incubation with bacteria, whereas the effect of the same proteolytic enzymes on bacterial growth was test ... | 1994 | 7478762 |
| immunoglobulin g response to subgingival gram-negative bacteria in human subjects. | serum and gingival crevicular fluid from normal healthy adults and patients with periodontitis were screened for immunoglobulin g antibodies to antigens from bacteroides gingivalis 381, bacteroides intermedius 24, bacteroides loescheii atcc 15930, fusobacterium nucleatum atcc 25586, eikenella corrodens 1073, actinobacillus actinomycetemcomitans atcc 29522, and capnocytophaga sp. strain m-12. immunoglobulin g antibody titers to the antigens were measured by an enzyme-linked immunosorbent assay. t ... | 1984 | 6735473 |
| bacteriological study of periodontal lesions in two sisters with juvenile periodontitis and their mother. | a total of five bacteriological samples from the periodontal pockets of two sisters with localized juvenile periodontitis and their mother with advanced periodontitis was studied. gram-negative anaerobic rods were predominant in the samples. bacteroides intermedius and bacteroides loescheii were the most predominant species. the antigenicity and bacteriocinogenicity of these isolates were quite similar. serum immunoglobulin g antibody levels of the subjects to gram-negative periodontopathic bact ... | 1984 | 6429040 |
| taxonomy of anaerobes: present state of the art. | results of nucleic acid studies, which indicate relationships among strains and species more clearly than do usual phenotypic tests, have led to new bacteriologic nomenclature. some major changes in bacteroides include the recognition of three species (bacteroides melaninogenicus, bacteroides denticola, and bacteroides loescheii) formerly grouped in b. melaninogenicus subspecies melaninogenicus; two species (bacteroides intermedius with two closely related homology groups and bacteroides corpori ... | 1984 | 6201990 |
| use of drugs in the treatment of obesity. | 2016 | 5025213 | |
| newer approaches in the bedside diagnosis of massive pulmonary embolism. preliminary report. | 2016 | 5009743 | |
| tobacco smoke: a noxious air pollutant. a review (and comment). ii of ii. tobacco smoke: general characteristics and composition. | 1971 | 4930344 | |
| current concepts in cirrhosis. | 2016 | 4917497 | |
| letter: animal experiments. | 2016 | 4832241 | |
| transplant problems. | 2016 | 4739346 | |
| suppressor cells in the rabbit appendix. | 1974 | 4547314 | |
| striatal tyrosine hydroxylases with high and low affinity for tyrosine: implications for the multiple-pool concept of catecholamines. | 1973 | 4148015 | |
| creatine kinase mb and m-mode echocardiographic changes in cardiac contusion. | cardiac contusion was suspected in 95 patients with severe blunt chest trauma of whom 93 did not require hospitalization. creatine kinase (ck) mb isoenzyme activity was elevated over 4.0 u/l in 10 (10.5%) patients (ck mb positive) by between 2% and 8% (mean +/- se 4.1 +/- 0.6%), when the total ck was 296 +/- 74 (mean +/- se). two patients had a pericardial rub. m-mode echocardiography was performed on 16 patients: 7 ck mb positive (ck mb+) and 9 ck mb negative (ck mb-) without the physician's kn ... | 2009 | 4096487 |
| [prevention of metastasis of laryngeal cancer by various methods of acting on the areas of regional metastases (a randomized study)]. | 2014 | 4095630 | |
| the epidemiology of accidental poisoning in children. | during a 1-year period (1 march 1982-28 february 1983) 272 children were admitted to the red cross war memorial children's hospital, cape town, after accidental poisoning. more boys than girls were admitted, and children between the ages of 12 months and 3 years were the most vulnerable. more than half the patients were coloured; blacks and whites represented minorities. most cases appear to occur during the summer months (november, december and january). medicines were responsible for most case ... | 2013 | 4035475 |
| the epidemiology of accidental poisoning in children. | during a 1-year period (1 march 1982-28 february 1983) 272 children were admitted to the red cross war memorial children's hospital, cape town, after accidental poisoning. more boys than girls were admitted, and children between the ages of 12 months and 3 years were the most vulnerable. more than half the patients were coloured; blacks and whites represented minorities. most cases appear to occur during the summer months (november, december and january). medicines were responsible for most case ... | 2013 | 4035475 |
| nearwork, school achievement and myopia. | 2014 | 3997918 | |
| igd myeloma. a study of four cases. | 2014 | 3938432 | |
| [effects of nitronaphthofurans on the transfer of a plasmid]. | 1985 | 3915195 | |
| persistence of antibodies to pneumococcal vaccine in patients with chronic renal failure. | antibody response to the 14-valent pneumococcal capsular polysaccharide vaccine was measured by the enzyme-linked immunosorbent assay (eia) in 17 renal allograft recipients, 29 azotemic, 11 hemodialysis, and 33 control patients. the igg, igm, and iga antibodies were measured against six pneumococcal antigen types 1, 3, 4, 6a, 8, and 19f. the control patients had the best antibody responses in the igg and iga antibody classes and the renal allograft recipients in the igm class. the renal allograf ... | 2014 | 3910915 |
| antimycotic 2-alkyldithio, 2-aralkyldithio, 2-aryldithiobenzamides. | some 2-alkyldithio, 2-aralkyldithio, 2-aryldithio benzoic acids, their methyl esters and n-monosubstituted amides were prepared and tested in vitro against candida albicans and trichophyton mentagrophytes. some n-monosubstituted amides displayed activities similar to those of clotrimazole and pyrrolnitrin. against candida albicans, n-monosubstituted amides exhibited a generally higher activity than the corresponding n-monosubstituted amides of 2,2'-dicarboxydiphenyldisulfide. | 1985 | 3910452 |
| [from the bibliographer's files (xxiv). 75 years ago]. | 2014 | 3900548 | |
| cloning of the e. coli o6-methylguanine and methylphosphotriester methyltransferase gene using a functional dna repair assay. | alkylating agents react with various nitrogen and oxygen atoms in dna and many of the products are substrates for repair processes. oxygen atom derivatives such as o6-methylguanine (o6-meg) o4-methylthymine and methylphosphotriesters (mp) have been shown to undergo repair by methyl group removal. the proteins involved in the latter reaction can be considered to be methyltransferases (mt) because their action results in the transfer of the methyl group to a cysteine residue within a polypeptide. ... | 1985 | 3889845 |
| cloning of the e. coli o6-methylguanine and methylphosphotriester methyltransferase gene using a functional dna repair assay. | alkylating agents react with various nitrogen and oxygen atoms in dna and many of the products are substrates for repair processes. oxygen atom derivatives such as o6-methylguanine (o6-meg) o4-methylthymine and methylphosphotriesters (mp) have been shown to undergo repair by methyl group removal. the proteins involved in the latter reaction can be considered to be methyltransferases (mt) because their action results in the transfer of the methyl group to a cysteine residue within a polypeptide. ... | 1985 | 3889845 |
| influence of inoculation sites and tumor cell culture techniques on the phenotype of a mixed cartilage- and bone-producing mouse mammary tumor. | we have previously reported the characterization of an intraperitoneally (ip) transplantable bone-forming mxt tumor. however, the question was unresolved as whether the bone-forming cells originated from either the host animal or from the neoplasm itself. the present work attempts to answer this question by studying the influences of inoculation sites (subcutaneously, sc; intraperitoneally, ip; in the brain, ib; intracranially, icr) on both the cartilage- and bone-forming tumor phenotypes. furth ... | 1986 | 3813489 |
| hypercalcaemia in hodgkin's disease. | 2013 | 3754677 | |
| contour interaction in the preschool child. | preschool children show poorer visual acuity when tested with multiple optotypes than when tested with isolated optotypes. this difference in performance could be the result of contour interaction or the greater distractions imposed by a multiple optotype display, which may be beyond a young child's ability. to differentiate between these alternatives, isolated and surrounded visual acuity were measured in children aged 2 to 7 years by pairing a landolt c with an o. the surrounded optotypes were ... | 2013 | 3717283 |
| levodopa pharmacokinetics and pharmacodynamics in fluctuating parkinsonian patients. | we investigated levodopa intravenous infusion rates, plasma concentrations, and clinical responses in 23 parkinsonian patients with a fluctuating response to the drug. there was a linear relationship between rate of levodopa infusion and plasma concentration when carbidopa was coadministered. minimum-therapeutically effective plasma concentrations of levodopa ranged from 3 to 12 nmol/ml. the duration, but not the magnitude, of clinical response was linearly related to plasma concentrations. the ... | 2013 | 3703280 |
| a computerized system for measuring detection sensitivity over the visual field. | a device is described for comprehensively measuring the capability of human operators to detect and react to visual signals occurring at a variety of locations throughout the functional visual field. the system is completely automated and computerized, and provides both documentation files and descriptive graphics of the operator's performance immediately upon completion of testing. sensitivity of detection can be measured for red, yellow, and green stimulus colors in a testing configuration whi ... | 1987 | 3632544 |
| [extracapsular cataract operations following traumatic lesions of the lens]. | 2013 | 3623375 | |
| [endometriosis in adolescent girls with developmental genital defects]. | 2013 | 3592085 | |
| [significance of the determination of c-peptide in type 2 diabetes]. | 2013 | 3548038 | |
| effect of a protease derived from the oral bacterium bacteroides loescheii on the inhibition of calcium-phosphate precipitation by human parotid saliva. | a protease from the culture fluid of this microorganism was purified and characterized using deae-sephadex and chromatofocusing and classified as a thiol protease with a mol. wt estimated as 27,500. it abolished the inhibitory activity of parotid saliva on the precipitation of calcium phosphate from supersaturated solutions. such proteases may contribute to dental calculus formation. | 1986 | 3541865 |
| excellence in leadership through organizational development. | 2012 | 3412664 | |
| evidence of estrogen receptors in normal human osteoblast-like cells. | in seven strains of cultured normal human osteoblast-like cells, a mean of 1615 molecules of tritium-labeled 17 beta-estradiol per cell nucleus could be bound to specific nuclear sites. the nuclear binding of the labeled steroid was temperature-dependent, steroid-specific, saturable, and cell type-specific. these are characteristics of biologically active estrogen receptors. pretreatment with 10 nanomolar estradiol in vitro increased the specific nuclear binding of progesterone in four of six ce ... | 1988 | 3388021 |
| intergeneric rosettes: sequestered surface recognition among human periodontal bacteria. | the human oral bacteria, streptococcus sanguis and bacteroides loescheii, when mixed in equal numbers in vitro, formed large settling coaggregates. as the relative number of each cell type was changed, coaggregates became smaller until at cell-type ratios of 10 to 1, rosettes formed. rosettes consisting of a streptococcal cell in the center surrounded by bacteroides cells exhibited surface recognition properties of only the bacteroides, which coaggregated with many other cell types such as actin ... | 1988 | 3377498 |
| use of inotropic and chronotropic agents in neonates. | the determinants of cardiovascular function include preload, myocardial contractility, and afterload. myocardial contractility and afterload can be altered pharmacologically and form the basis for the clinical management of shock with inotropic and chronotropic drugs. there are extensive data from experiments in laboratory animals that the immature cardiovascular system may respond differently to these inotropic and chronotropic agents than the mature cardiovascular system. digitalis, isoprotere ... | 2011 | 3322631 |
| the role of black-pigmented bacteroides in human oral infections. | today, 10 black-pigmented bacteroides (bpb) species are recognized. the majority of these species can be isolated from the oral cavity. bpb species are involved in anaerobic infections of oral and non-oral sites. in the oral cavity, bpb species are associated with gingivitis, periodontitis, endodontal infections and odontogenic abscesses. cultural studies suggest a specific role of the various bpb species in the different types of infection. bacteroides gingivalis is closely correlated with dest ... | 1988 | 3280611 |
| fatty acids and sugars in lipoplysaccharides from bacteroides intermedius. bacteroides gingivalis and bacteroides loescheii. | 1988 | 3268745 | |
| obesity in children. | 2011 | 3257638 | |
| [esthetic rehabilitation in fixed prosthodontics. ceramics without metal support]. | 2012 | 3255620 | |
| recurrence risk of neonatal hyperbilirubinemia in siblings. | the recurrence of neonatal hyperbilirubinemia (nhb) in full siblings was studied in 3301 live infants born between 1966 and 1986 to 1669 male us army veterans who were part of a nationwide health study. the study population included 580 sibships with one infant, 679 with two, and 410 with three or more. hospital of birth medical records were abstracted on these children. neonatal hyperbilirubinemia was defined as present if the recorded peak bilirubin level was greater than 205 mumol/l in the ab ... | 2010 | 3177302 |
| recurrence risk of neonatal hyperbilirubinemia in siblings. | the recurrence of neonatal hyperbilirubinemia (nhb) in full siblings was studied in 3301 live infants born between 1966 and 1986 to 1669 male us army veterans who were part of a nationwide health study. the study population included 580 sibships with one infant, 679 with two, and 410 with three or more. hospital of birth medical records were abstracted on these children. neonatal hyperbilirubinemia was defined as present if the recorded peak bilirubin level was greater than 205 mumol/l in the ab ... | 2010 | 3177302 |
| monochrome versus color for your video display. | 2011 | 3173012 | |
| age and infertility. | 2011 | 3105771 | |
| mechanisms of lymphocyte adhesion to human vascular endothelial cells in culture. t lymphocyte adhesion to endothelial cells through endothelial hla-dr antigens induced by gamma interferon. | the effects of interferons (ifns) on lymphocyte adhesion to cultured human vascular endothelial cells (ec) were investigated using an in vitro assay. endothelial cells obtained from umbilical vein were first cultured at a low density with a conditioned medium (cm) from 12-o-tetra decanoylphorbol 13-acetate-concanavalin a (tpa-con a) stimulated human peripheral blood lymphocytes (pbl), or with recombinant (r) gamma interferon (ifn-gamma) or r alpha interferon (ifn-alpha), and then were incubated ... | 1986 | 3084562 |
| diagnostic and prognostic importance of tumor markers in lung cancer. | 2011 | 3074224 | |
| regional localization of cd18, the beta-subunit of the cell surface adhesion molecule lfa-1, on human chromosome 21 by in situ hybridization. | the gene coding for the beta-subunit of the cell surface adhesion glycoprotein lfa-1 has been localized to the tip of the long arm of chromosome 21 at 21q22.1-qter. | 1988 | 3073708 |
| [unusual metastasis of a prostatic carcinoma]. | 2008 | 3022353 | |
| a computer-aided analysis of the effect of peripheral nerve transection on tmpase activity of substantia gelatinosa rolandi. | 1986 | 3020818 | |
| [clinicopathological study on malignant glioma--with special reference to gfap]. | in surgical specimens of 91 cases of malignant glial tumor, the correlation between the clinical malignancy of the tumors and the presence of gfa protein in the surgical specimen was examined. in anaplastic astrocytomas, 20 of 27 cases revealed positive staining of gfap. in the cases of glioblastoma multiforme 27 of 35 cases showed gfap positive staining. on the other hand, in medulloblastomas, all 29 cases were negative. in anaplastic astrocytomas and glioblastoma multiforms, the difference bet ... | 2010 | 3020463 |
| [clinicopathological study on malignant glioma--with special reference to gfap]. | in surgical specimens of 91 cases of malignant glial tumor, the correlation between the clinical malignancy of the tumors and the presence of gfa protein in the surgical specimen was examined. in anaplastic astrocytomas, 20 of 27 cases revealed positive staining of gfap. in the cases of glioblastoma multiforme 27 of 35 cases showed gfap positive staining. on the other hand, in medulloblastomas, all 29 cases were negative. in anaplastic astrocytomas and glioblastoma multiforms, the difference bet ... | 2010 | 3020463 |
| in vitro lipid oxidation modifies proteins and functional properties of sarcoplasmic reticulum. | changes in protein and fatty acid compositions of flounder sarcoplasmic reticulum during nadh plus ascorbate-dependent lipid peroxidation in vitro were related to the ability of the sarcoplasmic reticulum to sequester ca+2. progressive accumulation of high-molecular-weight protein components occurred concomitantly with loss of ca+2-sequestering activity. part of this polymerized protein may be the dimer or trimer of ca+2, mg+2-atpase. loss in ca+2, mg+2-atpase protein could account for over 60% ... | 2010 | 2943730 |
| localization and enumeration of fimbria-associated adhesins of bacteroides loescheii. | monoclonal antibodies that specifically inhibit coaggregation between bacteroides loescheii pk1295 and its two gram-positive partners streptococcus sanguis 34 and actinomyces israelii pk14 were used to enumerate and localize two distinct types of fimbria-associated adhesins on the surface of b. loescheii. binding studies with radiolabeled monoclonal antibodies indicated that a maximum (bmax calculated from scatchard plots) of approximately 400 adhesin molecules specific for s. sanguis and 310 ad ... | 1988 | 2893786 |
| characterization of monoclonal antibodies to fimbria-associated adhesins of bacteroides loescheii pk1295. | bacteroides loescheii pk1295 fimbriae, which mediate the lactose-sensitive coaggregation with streptococcus sanguis 34 and the lactose-insensitive coaggregation with actinomyces israelii pk14, were injected into mice to raise adhesin-specific monoclonal antibodies (mabs). supernatants of hybridomas were screened for the capacity to inhibit coaggregation and agglutinate intact bacteria. of the 10 mabs that were isolated, 4 were specific and potent inhibitors of the coaggregation between b. loesch ... | 1988 | 2891617 |
| fimbria-associated proteins of bacteroides loescheii pk1295 mediate intergeneric coaggregations. | bacteroides loescheii pk1295 serves as a coaggregation bridge between streptococcus sanguis 34 and actinomyces israelii pk14, two gram-positive oral bacteria that are otherwise unable to coaggregate. whereas coaggregation with s. sanguis 34 is inhibited by lactose, no simple sugar was found that inhibited coaggregation with a. israelii pk14. coaggregation-defective (cog-) mutants of b. loescheii pk1295 were isolated for the purpose of identifying the surface components responsible for the intera ... | 1987 | 2887546 |
| the challenge of malaria vaccine: trials and tribulations. | 1987 | 2880172 |