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experimental aspergillus endocarditis in rabbits.aspergillus endocarditis in man usually occurs on prosthetic cardiac valves and gives rise to large vegetations which embolize easily producing peripheral organ infarction and infection. blood cultures are usually sterile and the disease is difficult to cure with antimicrobial agents. aspergillus endocarditis was studied in rabbits to determine the course, degree of fungemia, and response to treatment with amphotericin b (a), 5 flucytosine (5 fc) or a + 5 fc. polyethylene tubing was introduced i ...19751102621
[aspergillus infection in skin transplantation and its therapy].in a 10 years old girl sustaining a corrosive injury of the lower leg from sulphuric acid, in the region of a skin transplantation colonization with aspergillus fumigatus (fresenium) and aspergillus niger (van tieghem) took place. this infection endangered the attempt of transplantation and the saving of the foot. treatment by medication with nystatin (moronal) and canesten (clotrimazol) were ineffective. pimaricin (pimafucin, natamycin) quickly erradicated the mycotic infection and secured an u ...19751102271
bronchial asthma in the nigerian savanna region. a clinical and laboratory study of 106 patients with a review of the literature on asthma in the tropics.one hundred and six asthma patients were studied in zaria in the nigerian savanna region. this group resembled hospital attenders in general in containing a disproportionately large number of immigrants from southern nigeria and students undergoing higher education. childhood asthma was rare. asthma started after the age of 19 years in 69 per cent of patients. twenty-seven per cent gave a history of rhinitis but none had had eczema. twenty-two per cent gave a family history of asthma. cutaneous ...19751101285
a new pathogenic species of aspergillus in the aspergillus fumigatus series. 19751101054
detection of fungi in clinical specimens by phase-contrast microscopy.during 1973 and 1974, the following fungi were detected in clinical specimens by using phase-contrast microscopy: blastomyces dermatitidis, 5; coccidioides immitis, 3; cryptococcus neoformans, 11; other yeasts 918; dermatophytes, 863; mucor species, 1; and aspergillus fumigatus, 16. this technique allows rapid detection and, in many instances, immediate identification of fungi in clinical specimens.19751100675
immunoglobulin classes of antibodies to aspergillus fumigatus in patients with pulmonary aspergillosis.an indirect immunofluorescence test was used to determine the titre and immunoglobulin classes of antibodies to aspergillus fumigatus in human serum. in 15 patients with aspergillosis, significant titres of igg but not iga or igm antibodies were found. the igg, iga and igm fractions of serum from 2 patients with aspergillosis were separated. this confirmed that antibodies to a. fumigatus reside in highest titre in the igg fraction. precipitating antibodies to a. fumigatus in these patients also ...19751099699
kinetic studies on the specificity of chelate-iron uptake in aspergillus.three strains of the fungus aspergillus, aspergillus quadricinctus (e. yuill), a. fumigatus (fresenius), and a. melleus (yukawa), each producing different iron-chelating compounds during iron-deficient cultivation, were used for 55fe3+ uptake measurements. iron from chelates of the ferrichrome-type family was taken up by young mycelia of all strains tested, irrespective of the ferrichrome-type compound these strains predominantly produce in low-iron cultures. ferrichrysin-producing strains, howe ...19751099079
letter: roentgenographically atypical pneumocystis carinii pneumonia. 19751098535
fatal aspergillosis in imported parrots.spontaneous fatal aspergillosis occurred in several species of parrots imported from latin america, australia, malaya and ghana for studies on the control of psittacosis. over a period of 4 years, 655 parrots were imported for use in these studies. all birds that died during these investigations were necropsied, and the internal organs of 45 were found to have macroscopic lesions suggestive of aspergillosis. of these 45 suspected cases, 32 were confirmed as aspergillosis by both histopathology a ...19751097931
experimental aspergillosis in normal rats infected intravenously. 19751097677
rast studies : ige antibodies to dermatogoides pteronyssinus (house dust mite), aspergillus fumigatus and beta-lactoglobulin in sudden death in infancy syndrome (sdis).the incidence of 2.5 sdis cases per 1,000 live births found in western australia is in agreement with figures reported for other centres. while the age range of sdis victims extended from two weeks to 15 months, 57 per cent of deaths occurred in children of two to four months of age. boys outnumbered girls 1.6:1. environmental factors are implicated in that the majority of deaths occurred in a biphasic distribution - autumn and late winter months. no significant differences were observed in tota ...19751097279
cerebral aspergillosis with special reference to cerebrospinal fluid findings.a case of cerebral aspergillosis in a 69-year-old diabetic man is reported. the disease, initially presenting as headache and vertigo, was caused by aspergillus fumigatus. seven csf specimens were examined. the main findings included decreased glucose and increased protein concentrations, leukocyte reaction and one positive culture for a. fumigatus. neuropathological examination revealed granulomatous leptomeningitis and typical fungal hyphae. the process probably lasted for more than 1 year and ...19751097253
effect of aflatoxin on phagocytosis of aspergillus fumigatus spores by rabbit alveolar macrophages.rabbits were given dialy doses of aflatoxin b1 equivalents of 0.03, 0.05, 0.07, and 0.09 mg for a 2-week period. macrophages were harvested at the end of the experimental period, and in vitro phagocytosis experiments were conducted using aspergillus fumigatus spores as ingestion particles. alveolar macrophages from rabbits given the above doses of aflatoxin had reduced phagocytic activity when compared with macrophages from control rabbits. incorporation of serum from the aflatoxin-treated rabbi ...19751096823
polyene sensitivity during germination of conidia of aspergillus fumigatus.a system for the rapid and relatively synchromous germination of conidia from a clinical isolate of aspergillus fumigatus is described. the polyene-mediated release of k plus from germinating conidia has been determined. ungerminated conidia were insensitive to amphotericin b methyl ester (ame) at concentrations greater than 50 mug/ml, but rapidly became sensitive to 1 to 2 mug ame/ml during the intitial stages of germination. these findings have been correlated with minimum inhibitory concentra ...19751095686
experimental aspergillosis in rats infected via intraperitoneal and subcutaneous routes.normal adult rats infected via the subcutaneous (s.c.) route with viable spores of aspergillus fumigatus develop serum antibodies, measured by passive haemagglutination and passive cutaneous anaphylaxis (pca), to extracts of the fungus. no significant histological abnormality was detected but s.c. inoculation in cortisone-treated animals induced the formation of granulomas frequently found in lymph nodes including those of the mesentery and paratracheal group. these granulomas were associated wi ...19751095475
letter: pulmonary aspergillosis, inhalation of contaminated marijuana smoke, chronic granulomatous disease. 19751094876
primary interaction between antibody and components of alternaria. ii. antibodies in sera from normal, allergic, and immunoglobulin-deficient children.antibodies in sera from normal, allergic, and immunoglobulin-deficient children were studied for binding to radiolabeled components of alternaria tenuis. significant binding levels were found in 103 of 105 sera from normal children. the levels were age-dependent, rising from a low point in the 7- to 12-month age group to adult levels by the age of 8 years. levels of binding to two antigens, a culture filtrate derivative (125i-clf) and a mycelial derivative (125-i-hs), were similar. sera from ast ...19751094055
effect of auxins and herbicides on enhancement of protein synthesis in fungi. 19751094049
keratomycosis in lucknow. 19751092323
toxigenic thermophilic and thermotolerant fungi.twenty-three isolates of fungi, representing 13 thermophilic and thermotolerant species, were bioassayed for toxigenicity to brine shrimp, chicken embryos, and rats. thirteen isolates representing nine genera were highly toxic to at least two of the three systems. seven additional isolates of five genera were slightly toxic.19751092262
cavitary pulmonary cryptococcosis complicated by aspergilloma.a roentgenogram of a 31-year-old office worker who had developed pleuritic pain showed multiple abscess cavities in the left lower lobe, and a clinical diagnosis of cryptococcosis was considered because of cryptococci recovered from a sputum smear and a positive indirect fluorescent antibody test. lobectomy (after unsuccessful amphotericin therapy) proved the presence of a destructive cryptococcosis with aspergillus proliferating in the cavities.19751092237
bronchocentric granulomatosis, mucoid impaction, and hypersensitivity reactions to fungi. 19751092235
characteristics of immunity in fungal infections. 19751092228
endogenous aspergillus endophthalmitis occurring after kidney transplant.two months after renal transplantation, a 26-year-old man developed pneumonia that was recalcitrant to antibiotic therapy and proved by biopsy to be due to cytomegalovirus and aspergillus fumigatus. ten days later while on amphotericin b therapy, he developed an endophthalmitis proved by smear and culture of a vitreous aspiration to be caused by a. fumigatus. despite intravitreous and systemic amphotericin b the vision deteriorated and the eye was enucleated. microscopic examination disclosed an ...19751092176
aspergillus infection of the nasal cavity of the dog: diagnosis and treatment. 19751091084
[aspergillosis as a postoperative complication of a jaw cyst]. 19751090912
ige antibodies to dermatophagoides pteronyssinus (housedust mite), aspergillus fumigatus, and beta-lactoglobulin in sudden infant death syndrome.the prevalence of serum ige antibodies to dermatophagoides pteronyssinus (house-dust mite), aspergillus fumigatus, and bovine beta-lactoglobulin was significantly greater in cases of sudden infancy death (s.i.d.) than in a control group of infants of the same age range. this difference was most pronounced with d. pteronyssinus antibodies, which suggests that hypersensitivity to house-dust mite may be a factor in the aetiology of s.i.d. in western australia. both the s.i.d. and control infants ha ...19751090327
occurrence of thermophilic microorganisms in peanuts and peanut soil. 19751089873
humoral and cellular immunity in asthma.parameters of humoral and cellular immunity have been measured in 91 asthmatic patients. mean serum levels of igg and ige were raised. igg levels were higher in those with a family history of asthma. ige levels were higher in those with a past history of atopic eczema, but intrinsic and extrinsic asthma could not be differentiated on the basis of ige levels. thirteen of 74 patients failed to respond to tetanus immunization, while only 1 failed to respond to salmonella typhi h antigen. tetanus no ...19751089697
allergic bronchopulmonary aspergillosis: evidence of limited tissue invasion.the cause of granulomatous parenchymal reaction in allergic bronchopulmonary aspergillosis has been attributed to a hypersensitivity reaction. a case is reported with aspergillus fumigatus identified in lung tissue, suggesting that the pathologic changes in some cases can be due to limited parenchymal colonization.19751089377
[incidence of aspergillosis in ex-coal miners suffering from pneumoconiosis]. 19751089079
aspergillosis of bone. 19751089024
immunological features of asthma (part ii). a report to the research committee of the british thoracic and tuberculosis association.a serological comparison was made of two groups of 120 matched asthmatic and healthy subjects, between the ages of 20 and 49 years and matched for age and sex, in terms of serum total levels of igg, igm, iga, igd and ige and of specific antibody levels in each immunoglobulin class to five common uk allergens. the relationship of clinical features to the serological tests was also examined in the asthmatic subjects. the following statistically significant findings were shown. the patients had hig ...19751053440
a study of fungal spore poupulations in the atmosphere of kuwait.the fungal air-spora of kuwait was investigated using the petri-dish trapping technique. during the period from 1st april, 1974 to 30th june, 1975, a total of 3685 colonies were recorded from 2% malt agar plates. fifty-five genera and 116 species were identifed. alternaria occupied the first place in the order of percentage incidence. being represented by 18.3% of the entire catch, followed by aspergillus (17.1%), penicillium (14%), cladosporium (13.6%), drechslera (13.3%), and ulocladium (7.1%) ...1976987536
factors which influence late cutaneous allergic responses.increased doses of ragweed antigen e, grass pollen extract, and the igg of sheep antiserum to human ige (anti-ige) were injected in intracutaneous tests in humans. with increasing doses of reactants, in individual subjects, there were the expected increases in the sizes of early wheal-and-flare responses; moreover, there was an associated increase in the magnitude and the frequency of late cutaneous allergic responses (lcar). lcar were shown to be a usual sequel to allergic reactions of sufficie ...1976947978
central nervous system aspergillosis in two young adults.unusual and unique features were present in the cases of two patients with central nervous system aspergillosis: one had a previously unreported complication of aspergillosis, extracranial internal carotid artery thrombosis documented by angiography, and in the other patient, cerebral granulomas developed from aspergillus fumigatus in association with intravenous narcotic abuse. the latter etiologic mechanism was suggested once before. neither of these patients showed other underlying disease. a ...1976944399
immunologic responses to therapy in allergic bronchopulmonary aspergillosis: serum ige value as an indicator and predictor of disease activity.two patients, a child and an adult, with allergic bronchopulmonary aspergillosis were studied over an 18-month period. initially elevated total serum ige levels fell during prednisone therapy and rose prior to and during an exacerbation. total serum igg fell with therapy, whereas the values of iga and igm remained constant. specific igg and ige values against aspergillus fumigatus as measured by radioimmunoassay were elevated in both patients. specific ige values increased in each patient prior ...1977925820
studies in chronic allergic bronchopulmonary aspergillosis. 1. clinical and physiological findings.this report outlines the clinical and physiological features in 50 asthmatic patients with chronic allergic bronchopulmonary aspergillosis in whom the diagnosis was made from 2 to 25 years ago (mean duration 10-9 years). from a questionnaire and analysis of the peak expiratory flow rate measurements it was found that they were worse in the winter months, corresponding to the maximal concentrations of aspergillus fumigatus in the atmosphere. nineteen patients reported daily sputum production of u ...1977882939
[a case of broncho-pulmonary aspergillosis developing for 24 years].a case of allergic broncho-pulmonary aspergillosis has been diagnosed on the basis of recurrent, transient pulmonary infiltrates, serum precipitins against aspergillus fumigatus and a dual-type reaction to intradermic testing with aspergillus antigen. despite a prolonged course (24 years), lung function tests do not show changes.1977834993
[aspergillus serum precipitins in patients of a lung clinic].the incidence and distribution of aspergillosis among patients of a lung clinic in west berlin were recorded. the immunodiffusion test (idt) was used on sera of 228 patients seen during one day to test for precipitins against a. fumigatus, a. flavus, and a. niger. precipitating antibodies specific against a. fumigatus were found in five patients, in two of them a. fumigatus was isolated simultaneously from sputum. in order to obtain a clear view of the clinical occurrence of asperigillosis and i ...1976821738
[mycological control of laboratory animals]. 1975821323
allergic bronchopulmonary aspergillosis: a study of 46 cases with special reference to laboratory aspects.a study of 46 cases of allergic bronchopulmonary aspergillosis has been presented with special reference to laboratory aspects. episodic airways obstruction and dual skin reaction to aspergillin were present in all the cases. furthermore, there were pulmonary infiltrations in 91.1%, blood eosinophilia in 80.4%, precipitins in 91.3%, and sputum cultures repeatedly positive for a. fumigatus in 82.6% of the patients. it was observed that the multiplicity of precipitin bands corresponded to the high ...1976821142
activity of amphotericin b, 5-fluorocytosine, and rifampin against six clinical isolates of aspergillus.amphotericin b in combination with 5-fluorocytosine was synergistic against three clinical isolates of aspergillus fumigatus and one of three clinical isolates of a. flavus. amphotericin b in combination with rifampin was synergistic against all six clinical isolates of aspergillus tested. the levels of 5-fluorocytosine and rifampin required for synergism were higher than clinically achievable concentrations when measurements of synergism were based on visual turbidity; but when the effects of t ...1976820247
antimicrobial susceptibility testing of six clinical isolates of aspergillus.several different methods of performing susceptibility tests on six clinical isolates of aspergillus are described. some of the conditions that affected the level of susceptibility to drugs were: the type of media used, temperature and time of incubation, and the initial inoculum size. for amphotericin b susceptibility testing, the effectiveness of the polyene antibiotic as measured by visual growth was equivalent to the effectiveness as measured by inhibition of ribonucleic acid synthesis and d ...1976820246
a comparison of aspergillus fumigatus antigens by counterimmunoelectrophoresis.counterimmunoelectrophoresis (cie) has been evaluated for routine diagnostic work, using antigens prepared from 2 different isolates of aspergillus fumigatus, at 2 different concentrations. additional antigens prepared in a variety of ways and 2 commercially available antigens (bencard, london; institut pasteur, paris, france) have been compared with the routine antigens. it has been shown that the use of the routine antigens will detect the majority of positive reactions. at optimal reacting co ...1976819832
detection of antibodies to aspergillus fumigatus in ager gel with different antigens and immunodiffusion patterns. 1976819444
mechanisms of activation of complement by extracts of aspergillus fumigatus. 1976819193
selenium effect on the growth of carcinogenic fungi and cytotoxic action of aflatoxin b1 on lymphocyte culture and on embryonal development of xenopus laevis.the authors report the results of investigations on the protective effect of selenium against teratogenic and cytotoxic action of aflatoxin b1 and the inhibitory action of this element on the growth of fungi producing carcinogenic aflatoxins. sodium selenate inhibited the growth of cultures of such fungi belonging to the class fungi imperfecti as aspergillus flavus, aspergillus fumigatus, penicillium meleagrinum and penicillium rougolosum. added to cell cultures of lymphocytes sodium selenate in ...1975817275
an aspergillus immunodiffusion test in the early diagnosis of aspergillosis in adult leukemia patients.an aspergillus fumigatus immunodiffusion test was performed biweekly for one year on 80 hospitalized patients with acute leukemia to determine if serologic conversion accompanied clinical aspergillosis. a micro-ouchterlony technique with agarose was used. the antigens were prepared from concentrated a. fumigatus culture filtrates and the sera were concentrated 3-fold before testing. of 80 patients, 10 were proved at autopsy, lung biopsy, or closed space culture to have invasive aspergillosis. si ...1976816237
[effect of the standard of hygiene in the care for breeding boars and of the technic of semen collection on the number of pathogens in the boar ejaculate].the microbiological examination of 48 ejaculates obtained by an artificial vagina revealed an average number of 178 000 germs per 1 ml of semen (1900 - 758 000). when the technique was changed, the manual method being employed, 23 ejaculates were obtained from the same boars and the microbiological examination revealed 44 200 germs per 1 ml of semen, on an average. in the second part of the trial 85 ejaculates obtained by an artificial vagina from 17 breeding boars were subject to microbiologica ...1975814677
cell-mediated immunity in patients with cystic fibrosis.leucocytes from 26 patients with cystic fibrosis (cf) and 18 healthy controls were investigated by migration inhibition induced by a variety of antigens. in patients with cf cell-mediated immunity was found to human lung and pancreatic tissue extracts as well as to aspergillus fumigatus, pseudomonas aeruginosa, and food antigens but not to brain, heart, or kidney. those patients with the severest form of the disease had the greatest impairment of cell-mediated immunity, but this impairment could ...1976813805
[on the prevalence of toxigenic aspergillus flavus strains in soviet-made food products].an analysis of 813 specimens of agricultural crops and 155 specimens of good quality products from retail trading establishments demonstrated that more than 50 per cent of them were contaminated with molds of the a. flavus species. from among 489 strains isolated the toxigenic ones comprised 5.1 per cent and according to their morphological characteristics they were referred to molds of the a. flavus and a. fumigatus and penicillium species. toxigenic strains were isolated only in specimens of a ...1975813386
hemolytic, cytotoxic and complement inactivating properties of extracts of different species of aspergillus.some of the biological properties of saline extracts of the mycelia of several species of the aspergillus genus, namely, a. fumigatus, a. flavus, a. niger, a. nidulans, a. parasitucus and a. glaucus, were studied. only the extract prepared from a. fumigatus was found to be hemolytic for sheep red blood cells. in contrast, all the extracts with the only exception of that of a. glaucus, had cytotoxic effects on vero cells. both, the hemolytic and cytotoxic constituents of the extracts were removab ...1975813147
counterimmunoelectrophoresis as a routine mycoserological procedure.counterimmunoelectrophoresis (cie) has been compared in a diangostic laboratory with agar gel double diffusion (dd) as a routine procedure for detection of antibodies to pathogenic and allergenic fungi and actinomycetes. it was shown to be of particular value in detecting antibodies to aspergillus fumigatus. thus 72 of 106 sera in which precipitins were detected were positive by cie alone. some sera were positive only by cie to antigens prepared from histoplasma capsulatum, allescheria boydii, c ...1975813146
detection of aspergillus fumigatus serum precipitins by counterimmunoelectrophoresis.detection of serum precipitins to aspergillus fumigatus by counterimmunoelectrophoresis is compared with the immunodiffusion technique. eight of nine (89%) sera from patients with proven a. fumigatus infection were positive by both methods. no serum from subjects with other systemic mycoses, bacterial infections, or healthy controls had detectable precipitins. the highest serum precipitin titers were found in sera of patients with the mycetomal and invasive forms of the disease. detection of a. ...1975812884
the general and specific humoral immune response to pulmonary aspergillosis.the genus aspergillus may cause one of several clinical entities in affected patients. serum specimens from 79 patients, including 41 with aspergilloma, 28 with allergic bronchopulmonary aspergillosis, 3 with both aspergilloma and the allergic variant, and 7 with invasive or disseminated aspergillosis, were studied for antibodies to aspergillus. the ammonium sulfate test was used with a mycelial component labeled with iodine-125 derived from aspergillus fumigatus. complement fixation and immunod ...1975812400
study of atmospheric fungi in a big cereal silo over a period of one year.a quantitative and qualitative study of the atmospheric fungi in a big silo was carried out over a period of one year (april 1973--april 1974). about 6 to 12 petri dishes with czapek medium were exposed for 5 minutes every month at different floors of the silo. the study showed:--a very high number of fungi colonies, reaching as many as 903 in march 1974 (a total of 60 min exposure); the dominant fungus was penicillium which was, however, overpassed in certain months by aspergillus (flavus and f ...1975810877
2-phenethylimidazole derivatives. synthesis and antimycotic properties.compounds of type (x = o, nh; ar and ar' = phenyl of substituted phenyl; ten examples) were prepared and assayed against miconazole (ii,x = o; ar = ar' =2,4-cl2c6h3) as potential antimycotic agents. optimal activity was noted for i(x = o; ar = ar' = 2,4-cl2c6h3), the direct analog of miconazole. it is about one-tenth as active.1975807735
antibody formation in rabbits exposed to aerosols containing spores of aspergillus fumigatus.rabbits were exposed once a day for 1 to 10 consecutive days to aerosols containing spores of aspergillus fumigatus. the number of spores used at each 5-minute exposure during an experiment was constant, but the level of exposure was different for each of the 4 experiments. precipitating antibodies were detected only in serums from rabbits that had inhaled at least 1.6 x 10-6 spores/g of lung tissue at each of 6 exposures or 1.8 x 10-6 spores at 2 exposures. a single exposure to 3.6 x 10-5 spore ...1975807135
phyllosphere microflora of some egyptian plants.the fungal and bacterial flora of the leaf surfaces of five plants growing in egypt were studied. the fungal flora showed seasonal fluctuations with at least one peak. twenty three genera with fifty three species were found, aspergillus and penicillium being most common. other fungi showed variable percentages of the total count. nitrogen-fixing bacteria were not isolated from the phyllosphere of the five plant species. micrococci were most predominant among the epiphytic bacteria. spore-forming ...1975806505
hydrogen peroxide sterilization of hydrophilic contact lenses.a new, simple, and effective procedure for the sterilization of soft contact lenses utilizes hydrogen peroxide, an inexpensive and readily availiable solution.1975805580
animal model of fusarium solani keratitis.because of the frequency of fungal keratitis due to fusarium solani, we needed a sustained, progressive infection in an animal model to determine the mechanisms of pathogenicity and to evaluate the new antifungal agents. pigmented rabbits interlamellarly injected with actively germinating conidia from lyophilized temperature-tolerant strains of f. solani produced sustained culture-positive ulcers in high percentage of eyes at two and three weeks, pretreatment with subconjunctival corticosteroids ...1975804817
cystic fibrosis--immunological reactions to a. fumigatus and common allergens.immunological studies of forty-three patients with cystic fibrosis showed that positive prick tests to at least one common allergen were obtained in 70%, to multiple allergens in 28% and to a. fumigatus in 50%. specific ige antibodies against these allergens were found in the appropriate subjects. in spite of this evidence of type 1, ige, sensitization none of the patients had a history of infantile eczema. intracutaneous tests with a. fumigatus extract gave types 1 and 3 reactions in sixteen pa ...1975802880
[properties of the contagious ecthyma virus used for vaccine production].experiments were carried out to establish the effect of some antibiotics and merthiolate on the vaccinal phylaxia strain of ecthyma contagiosa. besides, followed up was the effect of these antibiotics on concomitant microflora that had multipled in the virus suspension. trials were also made to titrate the vaccinal strain on lambs through scarification. titration was carried out by the method of schmidt. virus dilutions of 10-1 were applied following scarification on the the thighs and fore limb ...1976799865
[stages of development of aspergillus-mycetom and their roentgenographic signs (author's transl)].a series of 13 cases of aspergillus-infection in the respiratory tract are reviewed. a case of rapid development of an intrapleural aspergillus-mycetom is presented. a complete series of chest roentgenograms and operation-photos allowed to demonstrate like with a quick-motion apparatus 3 stages of development of an intrapleural aspergillus-myceton: i. infection through aspergilli of a residual intrapleural cavity by the bronchial way. pleural thickening as reaction to the irritation. ii. develop ...1976799407
roentgenographic recognition of bronchoceles.bronchoceles often have characteristic plain film, tomographic, and bronchographic appearances, and they may trap air. roentgenographic recognition of bronchoceles can allow them to be distinguished from neoplasms and sometimes help avoid unnecessary surgery.1976798296
[an antigenic extract analyzed by bidimensional immunoelectrophoresis (author's transl)].an antigenic extract from broth culture of aspergillus fumigatus has been analyzed by bidimensional immunoelectrophoresis of clark and freeman against rabbit antiserum. the analysis has show the extract to be constituted by seven different antigens.1976797324
[the possibility of an etiopathogenetic role of the fungi isolated from the respiratory tract (author's transl)].the large number of fungous strains isolated from specimens coming from the respiratory tract is a possible source of diagnostic failures. for an accurate diagnosis it is necessary to screen between fungi in a saprophitic and in a parasitic position. this is very difficult both for fungi, which are largely spread in the environment, like aspergillus sp., and for fungi, which are commonly found on the mucous membranes, like candida or torulopsis sp. the actual pathogenetic activity of a fungous s ...1976797323
radioallergosorbent test (rast) studies with insolubilized polysaccharides.polysaccharide preparations from aspergillus fumigatus and candida albicans when used with some human sera were found to fix complement and precipitate with specific antibodies present in the sera. precipitins consisted predominantly of igg with traces of igm and iga. following insolubilization of the fungal polysaccharide preparations with the n-carboxyanhydride of l-leucine, reactivity with serum precipitins was retained and reaction with ige antibodies was demonstrated using the radioallergos ...1976795563
extrinsic allergic alveolitis after aspergillus fumigatus inhalation. evidence of a type iv immunologic pathogenesis.three weeks after a massive inhalation of mold present on infected oats, a farmer's wife had extrinsic allergic alveolitis. aspergillus fumigatus was cultured from the moldy oats and from deep bronchial washings obtained at fiberoptic bronchoscopy. spores and hyphae characteristic of aspergillus species were demonstrated within granulomas in the pulmonary tissue obtained by transbrochial biopsy. serum precipitins, delayed (48 hour) cutaneous hypersensitivity and in vitro lymphocyte transformatio ...1976795300
[mucoid impaction of the bronchi (author's transl)]. 1976794963
[the effect of clotrimazole (canesten) on the ultrastructure of molds (aspergillus fumigatus) in the infected animal]. 1976794709
[removal of pulmonary aspergilloma by aspiration drainage]. 1976794564
[pleural aspergillosis in clinical records in the years 1965-1974]. 1976792829
[immuno-enzymatic technic (e.l.i.s.a.) applied to the serological diagnosis of human candidiasis and aspergillosis. preliminary results]. 1976792812
[comparative enzymatic study of two strains of aspergillus fumigatus and of a. fischeri of sapropytic origin or isolated from human or animal lesions: practical diagnostic applications].14 enzymatic activities (3 dehydrogenases and 11 hydrolases) were systematically investigated in the extracts of 2 strains of aspergillus fischeri and 14 strains of a. fumigatus (8 isolated from human or animal lesions named 'pathogenic' strains and 6 strains of saprophytic origin). the enzymic composition of a. fumigatus appeared to be very different from one strain to another but no relationships could be established between enzymic differences and origin of the strains. in addition, the immun ...1976792691
[dependence of the growth and toxin formation of aspergillus fumigatus fres.on the cultivation temperature]. 1976792639
hemoptysis with cavitary lung lesion. 1976792492
isolation of actinomycetes and fungi from mouldy hay using a sedimentation chamber. 1976791914
mycotic keratitis in nigeria. a study of 21 cases.a clinical and mycological study of 21 cases of mycotic keratitis, a clinical entity not yet reported from nigeria or west africa, showed that fusarium solani was the predominant aetiological agent. it was isolated from 12 cases. four of the remaining nine cases were caused by aspergillus fumigatus, one by a. flavus, two by penicillium citrinum, and one each by p. expansum and penicillium sp. all the 12 isolates of f. solani grew well at 37 degrees c and survived at 40 degrees c. two cases, one ...1976791355
direct fungal infection of the eye and its prevention. 1976791354
bilateral pulmonary aspergilloma in ankylosing spondylitis treated with transthoracic intracavitary instillations of antifungal agents.repeated transthoracic intracavitary injections of amphotericin b, nystatin and pimaricine proved a simple and safe method in the treatment of bilateral pulmonary aspergillomas in a patient with large cavities caused by lung disease in ankylosing spondylitis. both large mycetomas were dissolved by this treatment in combination with peroral corticosteroid medication, and the patient's general condition improved markedly.1976790560
salmonella and aspergillus infections in common loons overwintering in florida.during a 5-year period (1970-1975), 190 common loons (gavia immer) from overwintering populations on the east and west coasts of florida were examined for evidence of infectious diseases. salmonella spp (representing 8 serotypes) were isolated from 27 (14%) of the loons, and lesions typical of those produced by aspergillus fumigatus were found in 34 (18%) of the loons. seven loons were infected with salmonella spp and had lesions typical of aspergillus infection. the largest number of loons (124 ...1976789314
combination amphotericin b-rifampin therapy for pulmonary aspergillosis in a leukemic patient.pulmonary aspergillosis developed in a 62-year-old man with acute myelogenous leukemia. therapy with amphotericin b and 5-fluorocytosine was begun. synergy between amphotericin b and rifampin was demonstrated in vitro, and therapy with firampin replaced 5-fluorocytosine. progressive clearing of the pulmonary lesion ensued, suggesting in vivo efficacy as well. further studies of patients utilizing this regimen are warranted.1976789031
rast using crude and purified anti-ige.the sensitivity of the rast using anti-ige in 125i-labelled igg fractions of sheep antiserum was compared to that using anti-ige purified by immunosorbent techniques in tests with three allergens (grass pollens, aspergillus fumigatus and the detergent enzyme "alcalase") on sera from 248 workers in a detergent factory. both anti-ige reagents measure the same antibody but the rast procedure using the crude anti-ige reagent is less sensitive than that using the immunosorbent-purified anti-ige in it ...1976788951
incidence of serum antibodies to several aspergillus species and to candida albicans in cystic fibrosis.the incidence of serum ige antibodies to several species of aspergillus and the incidence of serum precipitins to these species and to candida albicans were determined in 22 children with cystic fibrosis, 17 children with bronchial asthma, and 18 control subjects. ige antibodies were found in 50 per cent of the patients with cystic fibrosis and in 29 per cent of the patients with bronchial asthma; none was found in the control subjects. precipitins to aspergillus species were present in 59 per c ...1976788564
aspergillus prosthetic valve endocarditis.the clinical, laboratory, and histopathological features of seven cases of aspergillus fumigatus prosthetic valve endocarditis are presented. the exact nature of the lesion, a combination of infective fungal endocarditis and thrombosis on the prosthetic valve, is discussed and the difficulties in clinical diagnosis are emphasized. helpful indications were sudden unexplained heart failure with the appearance of new murmurs, and emboli to large or medium-sized systemic arteries. fever and anaemia ...1976788218
an appraisal of impregon as a deterrent of domestic fungus growth.impregon brand of tetrachlorsalicylanilide (tcsa) has been profferred widely as a household fungistatic agent, although its value remains unproved. to assess its effects, this agent was used as a laundry and paint additive and as a treatment for burlap rug backing; after recommended applications of impregon, coded replicate materials were inoculated with mixed suspensions of fungus particles. no difference was evident in fungus growth points on fabric swatches washed in tap water with and withou ...1976787049
depletion of complement in vivo and in vitro by extracts of aspergillus fumigatus.a new, nontoxic material extracted from aspergillus fumigatus, is described with complement-depletion capacity both in vivo and in vitro. extracts of the mycelium of a. fumigatus were found to haemolyse sheep red blood cells, to be lethal for mice and to convert c3 into its faster electrophoretic form when incubated with normal human serum. conversion did not take place when purified c3 was used, suggesting that serum factors were required in the reaction. adsorption of the extracts with activat ...1976786901
intraocular effects of pimaricin.pigmented rabbits weighing 3 to 6 lbs were given bilateral intraocular injections of 250 to 1,000 mug pimaricin. following their injection, blood, aqueous and vitreous levels were determined at various time intervals during the first 24 hours and at 24 hour intervals thereafter for one week. in subsequent studies, pigmented rabbits were given bilateral intraocular injections of 5,000 spores of a. fumigatus and 30 hours later received intraocular injections of 250 to 1,000 mug pimaricin. these st ...1976786132
ige antibodies in bronchopulmonary aspergillosis.total serum ige and serum ige antibodies to a. fumigatus were quantitated in 143 patients with different forms of bronchopulmonary aspergillosis. total serum ige levels were elevated in all patients with allergic bronchopulmonary aspergillosis but also in some other forms of bronchopulmonary aspergillosis, thus limiting the diagnostic value of total serum ige determination in this type of pulmonary mycotic infection. specific ige antibodies to a. fumigatus could be demonstrated in all patients w ...1976786083
unusual mycotic findings in cytodiagnosis. 1976785916
[fluorescence immunologic studies of aspergillus fumigatus antibodies]. 1976782944
treatment of fungal sinusitis with autogenous vaccine. (a case report). 1976782005
[effect of different ratios and concentrations of carbon and nitrogen in the medium on the growth and toxin formation of aspergillus fumigatus fres]. 1976781478
sources and incidence of airborne aspergillus fumigatus (fres).specific surveys of the air for aspergillus fumigatus were carried out in rural and urban situations over a 2-year period. overall, low concentrations of spores were recorded with a higher incidence during the "winter" months. counts in the open air and in a hospital ward showed similar fluctuations, the indoor counts being consistently lower. plant debris in the form of compost heaps and stacks of hay and straw baled with a high moisture content in which self-heating occurs, produces large numb ...1976780000
[pathomorphology of pulmonary aspergillosis in tuberculosis patients based on according to resection material].to investigate various manifestations of broncho-pulmonary aspergillosis and to ascertain its association with a previous disease there were carried out histotopographic, histological and mycological studies of specimens of the lung tissue resected in 37 patients in connection with aspergillomas of the lungs and broncho-pulmonary aspergillosis. the investigations showed that aspergillosis was one of the forms of dysbacteriosis in the human organism and could develop against the background of pos ...1976779726
cystine aminopeptidase (oxytocinase) activity in plasma and tissues of normal and infected pregnant cattle.cystine aminopeptidase (cap) activity in tissues and in plasma from pregnant cows was measured at various stages of gestation by using the substrate s-benzyl-l-cysteine-4-nitroanilide. the cap activity was as high or higher in hepatic and renal tissues as in cotyledonary tissue. plasma cap activity was low and did not change with length of gestation, nor did it change when placentation was disrupted by infection with aspergillus fumigatus.1976779545
bronchopulmonary aspergillosis. an epidemiological study in a hospital population.in order to determine the incidence of bronchopulmonary aspergillosis in patients with other types of pulmonary pathology, 586 in-patients, out-patients and controls were examined during the period 1968-1970 in baguley hospital, manchester, england. it was found that from the 344 in-patients and out-patients with other pulmonary pathology, 6 had a definite diagnosis of allergic aspergillosis. 1 had pulmonary aspergilloma while 53 other patients demonstrated some evidence of bronchopulmonary aspe ...1976778964
proceedings: purification and characteristics of hemolytic toxin from aspergillus fumigatus. 1975778450
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