Publications

arylamidase activity of salmonella species.	arylamidase activity in cell extracts of sonically cell treated suspensions of 23 salmonella strains, including 12 strains of s. typhimurium, was investigated. all cultures hydrolyzed five of nine different neutral and basic substrates. activity against aspartyl-, cystyl- histidinyl-, and isoleucyl-beta-naphylamide was negligible. alanyl-beta-naphthylamide was the preferred substrate for the salmonella species; however, specific activities ranged widely. of several gram-negative organisms survey ...	1975	808165
divalent cation stimulation of the cell infectivity of shigella flexneri 2a.		1975	807763
substituted 1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones.	a series of 1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones has been prepared. a new synthesis of 4-alkyl-1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones involving the oxidative ring closure of 5-nitro-2-furaldehyde 2-(2-hydroxyethylalkyl)semicarbazones is described. the in vitro testing of the compounds against a variety of bacteria is reported.	1975	807733
trimethoprim-sulfamethoxazole in the treatment of gastrointestinal infections, including enteric fever and typhoid carriers.	forty-three patients suffering from typhoid fever, 11 from paratyphoid fever, six from bacillary dysentery caused by shigella flexneri, and nine carriers of salmonella typhi or s. paratyphi b, have been treated with trimethoprim-sulfamethoxazole compound. fifty-one of the 54 patients who had typhoid fever or paratyphoid fever responded satisfactorily to treatment. two patients with typhoid fever failed to respond and one died. in the patients with bacillary dysentery acute symptoms subsided rapi ...	1975	805647
the effect of leukocyte hydrolases on bacteria. iii. bacteriolysis induced by extracts of different leukocyte populations and the inhibition of lysis by macromolecular substances.	the lysis of 14c-labeled bacteria by hydrolases of human and rabbit leukocytes was studied in vitro. while staphylococcus albus, streptococcus faecalis, and streptococcus mutans were highly susceptible to lysis, staphylococcus auresus was intermediate in its susecptibility to lysis by the leukocyte enzymes. group a streptococcus, listeria monocytogenes, shigella flexneri, escherichia coli, and mycobacterium smegmatis were very resistant to degradation by these enzymes. the lytic activity of leuk ...	1975	804017
scanning electron microscopic studies on the microstructure of s and r type colonies of salmonella and shigella groups.		1976	802350
gastro-enteritis in egypt, certain epidemiological aspects.		1976	801623
[researches on antibiotic-resistance in "shigella sonnei" and "flexneri" and in "salmonella typhimurium" (author's transl)].	ampicillin (a), streptomycin (s), aminosidin (k), chloramphenical (c) and tetracycline (t) resistance was investigated in 130 s. typhi murium, 18 shigella flexneri and 13 shigella sonnei strains, recovered from enteritis cases in 1970-1973. all salmonella and 70% shigella strains (without any appreciable differences between sh. sonnei and flexneri) were found resistant and most multiresistant. a-s-k-c-t resistance was frequently found: in 48% of the salmonella and 12% of the shigella strains. as ...	1976	800942
resistance to antibiotics of shigella strains isolated in somalia.	the resistance to antibiotics of 240 shigella strains isolated in somalia from 1973 to 1976 was studied. many strains, particularly those of shigella dysenteriae type 1, were found to be resistant to more than one drug. in view of their resistance to ampicillin, chloramphenicol, streptomycin, tetracycline, and sulfonamides, it is suggested that polymyxin b or m sulfate - which have proved to be effective in vivo - should be used for the treatment of clinically typical cases of bacillary dysenter ...	1976	799953
generalized transduction of shigella flexneri by converting phage pe5.	phage pe5, responsible for the conversion of type v antigen in shigella flexneri, has the ability to produce generalized transduction. the correlation between phage multiplicity and the number of transductants, the specific inhibitory activity of anti-pe5 serum, and the lack of transduction in pe5 resistant recipients, indicate the role of phage pe5 in generalized transduction. transduction of the r100-1 factor resulted in a non-transmissible tetracycline resistance segragation. the characterist ...	1976	799898
[distribution of lysotypes and study of antibiotic sensitivity of shigella flexneri 2 isolated in iran].	152 strains of shigella flexneri 2 isolated from the stools of patients having sporadic bacillary dysenteria have been studied for their phage types as well as for the presence of transferable resistance factor. the distribution of the phage types has shown a high predominance of lysotype 12 (67%). proportion of shigella flexneri 2 strains resistant to one or several antibiotics has been highest in the years 1968 and 1973. the most frequent transferable resistance pattern was found to be (tc, cm ...	1976	799541
[production and characteristics of glycerin mutants of s. typhimurium].	s. typhimurium glycerine mutants-gly 90 and gly 87 were obtained under the action of ethylmethanesulfonate. the mutants obtained were characterized by the site of block in the course of glycerine utilization:gly 90 mutant bore the mutation in the glp k-gene, this leading to the defect by glycerokinase-the enzyme of the first stage of glycerine metabolism; gly 87 mutant had derangements in the other stage of glycerine utilization. both mutants lost their capacity to induce keratoconjunctivitis in ...	1976	799451
[antibodies to enteropathogenic bacteria in the saliva of patients with different forms of acute intestinal diseases and healthy subjects].		1976	799368
[substantiation for the kanamycin treatment of certain diseases, taking into account its concentration at the sites of localization of the causative agent (an experimental study)].	kanamycin concentration in the inflammatory foci was studied on experimental models of pneumonia, maxillary sinusitis and acute dysentery. the kanamycin levels in the sites of the pathogen localization were lower than those in the same tissues of healthy animals. the antibiotic dose should be chosen with the account of its concentration in the focus of the pathogen localization rather than in the blood serum.	1976	798542
[chemotypes of "shigella flexneri" r mutants and related phage receptors. i. -- chemical study of the lipopolysaccharides (author's transl)].	the f6r rough mutants isolated from shigella flexneri f6s, serotype 5b, and the fh rough mutants, derived from other serotypes of s. flexneri, were chemotyped according to the chemical analysis of their lipopolysaccharides. further, the following stages of lipopolysaccharide core biosynthesis in s. flexneri have been established: --(kdo)3--heptose--heptose--glucose--galactose; the last three stages are: either --glucose--glucosamine--glucose, or --glucosamine--glucose--glucose. the results of th ...	1976	798513
[chemotypes of "shigella flexneri" r mutants and related phage receptors. ii. -- localization of phage receptors (author's transl)].	receptor sites for phages fp3, v, p1kcvir, h+, c21, t4, t3, t7 and 6sr have been investigated, by comparing the lytic activity of these phages on r mutants of strain f6 (f6r) and of various serotypes (fh) of shigella flexneri with their inhibition by the lipopolysaccharides isolated from these mutants. the results suggest the following localizations for the receptor sites: phage fp3: lipid a-kdo; phage v: heptose or glucose; phage c21: heptose-glucose; phages h+, p1kcvir, t4 and t3: glucose; pha ...	1976	798512
restriction and modification of shigella flexneri phages by r factors.	out of 420 r factors derived from shigella flexneri strains, 50.8% restricted escherichia coli and s. flexneri phages. phage restriction was produced both by fi- and fi+ r factors. the r factors were divided into nine groups on the basis of the efficiency of plating of s. flexneri phages. changes of phage types were produced by transferring r factors of different restrictive types. the changes offered some information concerning the evolution of phage types. studies on phage modification support ...	1976	798471
r factors derived from shigella flexneri strains.	of 2492 shigelle flexneri strains isolated from dysenteric patients in hungary in the years 1972-1974, 767 (30.8%) were resistant to 1-5 antibiotics. resistance was due to r factors in 79.2% of the strains. fertility inhibition experiments with f specific phages showed r factors to be fi+ in 12.9% and fi- and 87.1%. of the antibiotic markers, the chloramphenicol-tetracycline resistance determinant was the most common (46.4%). chloramphenicol resistance determinants were carried out by fi- r fact ...	1976	798470
[ultrastructural changes in mucosa of the distal portion of the large intestine of patients with dysentery].	the ultrastructure of the mucosa of the large intestine was studied in 10 patients with acute dysentery. the group of patients included 7 women and 3 men aged 17--50 years. diagnosis was confirmed in all cases bacteriologically (by isolation of sonne shigella in 4 patients and flexner shigella in 6 patients). the electron-microscopy study of bioptats of the mucosa showed that in the inflammatory process all its cells--prismatic, gobletcells, and enterochromaffin -- took part, although not in the ...	1976	797360
[role of colicinogenicity in the mechanism of the antagonistic action of sonne and flexner shigellae].		1976	797188
[dysentery in the city of białystok in the years 1961-1974].		1976	796895
[ultrastructural features of the interaction of salmonellae and shigellae with the cell].		1976	796637
[a study of pancrealysates of sh. flexneri 2a and sh. sonnei fractionated by filtration through sephadex g-200 and ultracentrifugation].	a high-molecular fraction of the o-antigen of sh. flexneri and sh. sonnei was isolated from the antigen complex by gel-filtration through sephadex g-200 and ultracentrifugation. the high-molecular fraction obtained by ultracentrifugation at 105000 g contained no low-molecular components.	1976	795248
[changes of various factors of nonspecific humoral immunity in acute dysentery].	the level of total enterobacterial enterotoxins of the blood serum, of beta-lysins, lysozyme activity, complement and normal antibodies were studied in 191 patients with acute flexner dysentery and in 285 patients with acute sonne dysentery, depending on the period of the disease, its severity, the treatment applied, and the species of the causative agent. the level of the nonspecific humoral immunity factors increased before the treatment and its normalization depended on the treatment applied.	1976	795232
[interaction with the hep-2 epithelial cells of sh. flexneri r mutants and hybrids differing in o antigen structure].	the results of a study of the interaction of the r-mutants of sh. flexneri of various chemotypes and shigellae hybrids with a definite genetic characteristics differing by structure of the o-antigen labeled with 3h-glucose, with the cells of the hep-2 line demonstrated that the presence of the full value lipopolysaccharide structure apparently promoted the fixation of shigellae to the epithelial cells. the rough shigellae strains could retain the capacity to penetrate into the cells and to multi ...	1976	795229
[importance of cellular and humoral immunity factors in dysentery in children].		1976	795153
[comparative susceptibility of animals to sonne and flexner dysentery].		1976	794642
phage-dependent changes in shigella flexneri type antigen synthesis.	lysogenic conversion of shigella flexneri type antigens was studied with the aid of wild-type and thermosensitive mutant phages. with all wild-type phages, the appearance of glycosylated antigen was accompanied by the appearance of polyprenyl phosphate glucose synthetase activity. with some of the mutant phages, the appearance of glycosylated antigen was not followed by the formation of lipid-linked glucose in the enzyme assay. the reverse has also been observed, i.e., the high rate of formation ...	1976	793990
[formation of f'-episomes in flexner shigellae].	genetic characteristics of shigella flexneri virulent donor strain 3s, isolated in the laboratory, are studied. the data obtained showed that sh. flexneri 3s 6832 is of f'protype it did not transmit even closely located chromosome markers, except pro+. the transition of pro+ marker was reproduced in reca- strain. f'pro plasmid was eliminated with a frequency similar to that of f'lac factor in the control strain of escherichia coli. the study of virulence by means of keratoconjunktival test revea ...	1976	793929
studies on the relationships between the immunogenicity and catabolism of antigens and their binding to the surface of macrophages.	the relationship between immunogenicity of shigella paradysenteriae, the branched synthetic polypeptide poly-l (tyr, glu)-polylpro-polyllys [(t, g)-pro--l] and human albumin (hsa) interacting with macrophages and kinetics of antigen degradation and degree of binding to the cell surface was studied. following thioglycollate inoculation into c57bl/6 mice, the peritoneal-stimllated macrophages had higher levels of hydrolases as compared to unstimulated cells. the lysates of the stimulated macrophag ...	1976	793850
[change in the sensitivity of dysentery bacteria to certain antibiotics, furazolidone and antifungal preparations when cultured together with candida albicans].	the effect of candida albicans (2 collection cultures and 1 freshly isolated culture) on sensitivity of dysentery bacteria (5 zonne strains, 4 flexner strains and 2 newcastle strains) to antibiotics, furazolidone and their combinations with nystatin or decamine was studied by the method of serial dilutions. a total of 937 tests were performed with the use of 10 concentrations in each test. it was found that sensitivity of the shigella to levomycetin succinate, monomycin and furazolidone decrease ...	1976	793515
[free amino acid content in the blood and urine from the use of monomycin on children with dysentery].	the progress of acute dysentery in 73 children at the age of 1 to 14 years treated with monomycin and the levels of free amino acids in the blood and urine in dynamics were studied. it was found that the blood levels of 6 amino acids in the children treated with the antibiotics significantly decreased, while those of 3 amino acids increased as compared to the levels of the same amino acids in the children treated without the antibiotics. it was concluded that the diet of dysentery children treat ...	1976	793513
studies on the energetic metabolism of shigella flexneri x escherichia coli hybrids devoid of penetration ability. iv. growth characteristics in the presence of some tricarboxylic acid cycle intermediates.	the dynamics of avirulant lac+kcp- hybrids sh. flexneri multiplication was investigated in minimal medium in the presence of some tricarboxylic acid cycle intermediates (fumarate, succinate, malate) and pyruvate. it was established that in spite of the loss of virulence in the rate of the multiplication of the hybrid strains, in comparison with that of the virulent recipient strains of sh. flexneri, considerable differences were not observed.	1976	793258
[effect of specific sensitization of the body on the clinical symptoms of dysentery].		1976	793040
shigellosis in the united states: ten-year review of nationwide surveillance, 1964-1973.	in the 10 years 1964-1973, 105,832 isolations of shigellae were reported to the center for disease control through a nationwide surveillance system. the number reported increased by approximately 13% annually, from 5852 in 1964, when only 17 centers reported all 4 quarters; to 16,797 in 1973, when 52 centers reported each quarter. the rate of reported isolations varied from 4.6 per 100,000 persons in 1965 to 9.1 per 100,000 in 1973. shigella sonnei accounted for 64% of all these isolates and for ...	1976	790947
on the metabolic characteristic of hybrids shigella flexneri x escherichia coli devoid of their ability for intracellular multiplication in the epithelial cells. ii. catalase and phosphatase activity.	the catalase and phosphatase activity of avirulent by keratoconjunctival test of guinea pigs xyl+ and xyl-str (kcp-) hybrids that have lost their ability for intracellular multiplication, received from virulent strains. sh. flexneri (sh. flexneri 222 5 a and sh. flexneri m42-43) and donor strain e. coli ab 313 was investigated. it is established that there is a definite dependence between the changes in the catalase and the phosphatase activities of the hybrid strains and the newly received by t ...	1976	790854
on the metabolic characteristic of hybrids shigella flexneri x escherichia coli devoid of their ability for intracellular multiplication in the epithelial cells. i. glycolysis.	the glycolysis (aerobic and in the presence of kcn) of avirulent xyl+ and xyl-str hybrids sh. flexneri x e. coli, devoid of their ability to multiply intracellularly in the epithelial cells, is studied. it is established that their glycolytic activity is considerably higher than the activity of the donor strain e. coli, and deviate significantly compared with shown activity of the virulent recipient strains sh. flexneri. xyl-str hybrids are showing high values of glycolysis in aerobic conditions ...	1976	790853
[transmissive plasmid determining hemolysin production and synthesis of thermolabile k-antigen].		1976	790826
[comparative study of the virulence of an antibiotic-sensitive strain of flexner dysentery and its exconjugants with different r-factors acquired in the experiment].		1976	790825
[change in the virulence of flexner shigellae following transmission of several parts of chromosomes related to the synthesis of o-antigen lipopolysaccharide from e coli k-12 and r-mutants of shigellae].		1976	790821
[realization of the cytotoxic properties of flexner shigellae in a macrophage culture at the cellular and subcellular level].		1976	790819
[role of the cytotoxicity of shigellae in the infectious process].		1976	790818
[cytotoxic factor of flexner shigella, its biologic function and genetic control].		1976	790817
shigellosis transmitted by nurses.	twelve cases of shigella sonnei infection, with two deaths, occurred at a custodial institution in donelson, tennessee, in april and may 1973. nine of the cases and both deaths were in patients hospitalized at the institution's infirmary. the patients with nosocomial shigellosis were significantly younger and had been hospitalized significantly longer than controls. epidemiologic investigation implicated staff members in the transmission of illness from one patient to another and identified the ...	1976	790590
[shigellosis in tucumán].	in 731 diarrhea cases studied from january 1971 to june 1973 in tucumán a significant increase of shigellosis in eutrophic children was observed. the frequency of shigella isolations, considering all the enteropathogens found, were: 15,5 %; 13 % and 21,3 % in 1971, 1972 and 1973, respectively (table 1). all the strains of shigella isolated belonged to the shigella flexneri b or shigella sonnei d groups, being the percentage for the former 78 % in 1971; 93 % in 1972 and 77 % in 1973 (table 2). th ...	1975	790480
[ 771 shigella strains isolated in a 15-year period from americans living in ankara. comparisons with shigella strains isolated from turkish natives].	the author had worked as a bacteriologist in ankara american air force hospital from 1958 to 1972. during this period of time he was able to isolate 771 shigella strains from the american patients of the hospital. the amounts and the percentages of the subgroups are listed below together with the two other ankara city pediatric hospital results (see article). american community lived in ankara for 15 years and shared many aspects which were important in shigella epidemiology like using city's ta ...	1976	790107
fecal steroids in diarrhea. i. acute shigellosis.	fecal bile acid and neutral sterol patterns of five healthy adult male volunteers, who were challenged by a virulent shigella flexneri 2a (m42-43) strain and developed dysentery were studied. it was observed that cholic acid was increased from 1.9 +/- 0.4% of total bile acid in the feces before infection to 14.5 +/- 2.1% during diarrhea (p less than 0.001). chenodeoxycholic acid also was increased from 3.2 +/- 0.7 to 8.7 +/- 3.2% in diarrhea but the difference was not significant statistically. ...	1976	786002
[antibody-containing cells in the mucosa of the large intestine of patients with acute bacterial dysentery].	the authors traced the dynamics of appearance, increase and disappearance of o-antibody-containing cells in the mucosa of the distal portion of the large intestine in patients suffering from acute sonne and flexner dysentery (aspiration biopsy of the mucosa). the antibodies were revealed by the indirect coons method. the total number of cells per 1 mm2 of 4 mum of the mucosal section the number of lymphoid cells and the content of the antibody-containing cells in % per total cell count of the ly ...	1976	785886
[epidemiology of bacterial dysentery in the usa].		1976	785885
antigenicity testing of inactivated oral enteric bacterial vaccines for human use.	this study deals with the laboratory testing of the antigenicity of inactivated oral enteric bacterial vaccines for human use, viz. typhoid, dysentery, escherichia coli and cholera vaccines. for the assays the following methods are applied : 1) various types of active mouse protection tests 2) serum and coproantibody determinations in immunized persons and experimental animals, 3) protective ability of the immune sera in mice and embryonated eggs, 4) hemolytic and bacteriolytic plaque assays. it ...	1976	782974
[use of the vshs elective-differential medium in the diagnosis of dysentery and other acute intestinal infections].	results of trial of the vshs medium under conditions of direct seeding feces of patients suffering from dysentery and other acute intestinal disturbances demonstrated that by the efficacy of sh. sonnei isolation it failed to differ from ploskirev's bactoagar, was less effective in comparison with levin's medium with levomycetin (the incidence of shigella isolation was 49.7, 52.6 and 60.3%, respectively) and was the most effective in sh. newcastle isolation. in seeding feces after their enrichmen ...	1976	782114
[increasing the frequency of the transmission of antibiotic resistance in bacteria through their centrifugal sedimentation].		1976	782110
[the role of the water factor in the spread of dysentery on river vessels].	results of epidemiological and statistical analysis of the indices of dysentery morbidity and bacteriological examination of drinking water pointed to the significant role of the water factor in the spread of dysentery on the river vessels.	1976	782097
[an electron microscopic study of the interaction between shigellae and cell cultures. ii. structuro-functional response of the chief cytoplasmic organoids of infected cells].	the initial mobilization of the protective power of amniotic cells under the influence of the intracellular parasite shigellae flexner was shown using qualitative and quantitative methods of electron microscopy. this mobilization is seen in the appearance and then concentration of membrane elements of the endoplasmic reticulum around the bacteria. the character of some degenerating changes confirms the opinion about the presence of an excreting endotoxin fraction in shigellae flexner.	1975	781958
serum amylase in rats following the administration of endotoxin.		1976	781914
proceedings: inactivation and mutation of cultured mammalian cells by radiations of different let.		1976	779917
shigellosis in custodial institutions. v. effect of intervention with streptomycin-dependent shigella sonnei vaccine in an institution with endemic disease.	a double-blind controlled field trial of live, oral, streptomycin-dependent shigella sonnei vaccine was begun in an institution with endemic s. sonnei disease. considerable unexpected child-to-child transmission of the vaccine strains inadvertantly caused the field trial to resemble a mass vaccination campaign. although s. sonnei accounted for 90% of shigella infections from 1968 to 1971 and three-fourths of the cases occurred in the seven study cottages, s. sonnei disease disappeared following ...	1976	779465
[importation of shigelloses into the german democratic republic].		1975	779290
proceedings: on new biological responses of conventional adult mice administrated with bacterial endotoxin.		1975	778449
shigella flexneri 6 biotypes: a review.	except in gas production, s. flexneri 6 is generally similar to other s. flexneri. s. flexneri 6 contains both aerogenic and anaerogenic strains which are identical serologically. it is not surprising that s. flexneri 6 is not separable from other s. flexneri types on the basis of dna relatedness (overall genetic makeup) (4). the manchester biotype is seen in the united states, and is easily separable from other enterobacteriaceae by biochemical tests. one can no longer assume à priori that any ...	1976	776900
studies on the survival of shigella flexneri in river and tap water.		1975	776123
[characteristics of the salmonella and shigella strains isolated from diarrhea patients during antibiotic therapy].	drug resistant strains of salmonella and shigella were isolated from diarrhoeic children during antibiotic treatment. two strains of sh. flexneri serotype 2a, resistant to sulfonamides, streptomycin,chloramphenicol, and tetracyclines, were able to transfer "en bloc" their resistances to e. coli k12.	1975	776095
[correlation between biochemical features and pathogenicity of shigella. iv. threonine deaminase of shigella strains producing and not producing keratoconjunctivitis in guinea pigs].		1976	775224
shigella hepatitis.		1976	775138
[the influence of several prophages on the genetic behavior of flexner dysentery bacteria].	in conjugation experiments of escherichia coli k-12 hfr strains and converted clones of shigella flexneri var. y(-:3,4) that had acquired the capacity to synthesize type of antigens iv or v it is confirmed that the locus linked to lac-pro region in sh. flexneri chromosome called tp locus is a site of an attachment of prophages responsible for certain type specific antigens. lac+ hybrids of the clone converted by phage iv lost the type specific antigen iv with the frequency comparable with the lo ...	1975	773758
[observations on the sensitivity to antibiotics of the shigella isolated from patients in 1966-1973].	sensitivity to levomycetin, streptomycin, chlortetracycline, oxytetracycline, monomycin, neomycin and erythromycin of 3766 strains of shigella isolated from dysentery patients within 1966-1973 was determined with the method of standard discs. the strains proved to be resistant to tetracycline (94.3-99.4 per cent), streptomycin (85.1-94.9 per cent) and levomycetin (69-93.1 percent). by present the dysentery bacilli have preserved their sensitivity to monomycin (88.2 per cent) and neomycin (98.2 p ...	1975	773290
isolation and analysis of the lipid a backbone. lipid a structure of lipopolysaccharides from various bacterial groups.	a degradation procedure of lipopolysaccharides was worked out which allows the isolation of the reduced backbone of lipid a in a total yield of between 20 and 30%. this procedure was applied to lipopolysaccharides of s forms (salmonella minnesota, shigella flexneri 5b, escherichia coli 086, e. coli 0111, xanthomonas sinensis, rhodopseudomonas gelatinosa) and r mutants (salmonella minnesota, shigella flexneri, 5b, e. coli bb9 and e. coli eh 100). chemical analysis, reaction with beta-n-acetyl-glu ...	1976	770165
[bacteriological and epidemiological considerations on shigelloses in south vietnam (1969-1973)].	during the period from 1969 to 1973, a rectal swabs from 13.943 diarrhea patients of all ages were examined by bacteriological surveys. from these specimens, 981 strains of shigella were isolated. the most commonly encounted were shigella flexneri 2. all of strains of shigella isolated were highly resistant to aureomycin, tetracyclin, terramycin, novobiocin and chloramphenicol. there has been an increase in the development of multiresistance of shigella. colimycin and streptomycin were the most ...	1975	770024
[intestinal localization of shigellae in dysentery and experimental shigellosis].	the investigation of 53 section cases of dysentery and 18 biopsy specimens of the large intestine in acute dysentery in children showed that intrapithelial distribution of shigella was not always regular. in studies of experimental shigellosis on isolated loops of the intestine 459 segments of the intestine of 51 rabbits were investigated. the results obtained showed that shigella multiplied mainly in the lumen of the intestine. the increase in number of shigella in enterocytes was by 8-9 orders ...	1976	769758
diagnostic value of indirect hemagglutination in the seroepidemiology of shigella infections.	to evaluate the usefulness of the indirect hemagglutination (iha) test in the epidemiological investigation of shigellosis, single serum specimens were tested from 50 patients with shigella dysenteriae 1 (shiga bacillus) infections, 103 asymptomatic contacts of these cases, 267 adult and 100 student control, and serum specimens collected during two outbreaks caused by s. sonnei and one outbreak due to s. flexneri 6. in patients with s. dysenteriae 1, 74% demonstrated titers of greater than or eq ...	1976	767361
comparative serologic analysis of lac+ recombinants of serotypes 2a, 2b, 5a and variant y of shigella flexneri.	the serologic structure of lac+ recombinants of 2a, 2b, 5a and var. y serotypes of sh. flexneri was compared. rec. 2a lac+, rec. 2b lac+ and rec. y lac+ were shown to be identified, and rec. 5a lac+ was found to differ from those mentioned in that it was deficient in determinants for 3,4 group antigen complex. furthermore, the paper discusses the presumable genetic mechanisms of the described variability.	1975	766722
immunochemical studies on the serotype of shigella flexneri and its recombinant.	chemical and serologic analysis of polysaccharides of shigella flexneri 2b and its recombinant revealed complete defect of the gene responsible for type ii specificity as a result of recombination. at the same time, function of the gene in the same locus responsible for 7,8 group specificity was partially inhibited. attenuation of group antigen 7,8, associated with partial uncovering of the structure of the basic chain, causes appearance of a distinct 3,4 group antigen. changes of this type in s ...	1975	766721
[characteristics of bacteriophages used in the detection of disturbances in the synthesis of the o-antigen polysaccharide of shigella flexneri].	a study was made of the sensitivity spectra of various strains of sh. flexneri and r-mutants of various chemotypes to bacteriophages used for lysotyping of shigellae and to some bacteriophages specific of the r-mutants of salmonellae and e. coli. as a result of study there was selected and characterized a collection of bacteriophages specific of the s-strains and r-mutants of shigellae of different chemotypes, which could be used in genetic and immunochemical investigations.	1975	766530
[construction of new types of chemical vaccines for the prevention of intestinal infections, and their qualitative assessment. iv. physical properties and immunological characteristics of the experimental series of chemical vaccines presented for comparative study].	the authors present the results of study of physico-chemical properties of the chemical sorbed monovaccines from the antigens of the causative agents of typhoid fever, paratyphoid a and b and sonne and flexner dysentery obtained by various methods; the results of investigation of their reactogenic properties and immunological activity of limited groups of volunteers also given. the vaccines from the antigens obtained by sparing methods were less reactogenic than the rest experimental and control ...	1975	766526
[rectoromanoscopic pictures in dysentery associated with helminthic diseases].		1975	765713
[phagocytosis of shigellas with hela cells].		1975	765698
[cellular infiltration of shigella].		1975	765541
trimethoprim-sulfamethoxazole therapy for shigellosis.	twenty-eight infants and children hospitalized for severe shigellosis were treated orally either with ampicillin trihydrate (100 mg/kg/day administered in divided doses every six hours) or with trimethoprim-sulfamethoxazole (trimethoprim, 10 mg; sulfamethoxazole, 50 mg/kg/day in divided doses every 12 hours) for five days. four patients with ampicillin-resistant shigellae continued to have diarrhea and positive stool cultures during therapy. patients with susceptible shigellae treated with ampic ...	1976	765518
oxolinic acid for the treatment of chronic gastrointestinal shigella carriers.	two patients were long-term gastrointestinal carriers of shigella flexneri for 23 mo and 6 mo, respectively. neither patient responded to oral antibiotics, despite in vitro sensitivity of the bacteria to the antibiotics administered. oral oxolinic acid produced immediate cessation of the carrier state in both patients, with resolution of minor but persistent physical complaints.	1978	686252
dog bites.	dog bites can be prevented by proper education of children, appropriate selection of family pets and the restraint of guard dogs in the community. an unusually high incidence of bites by german shepherds was observed in this study. treatment of injuries inflicted by dogs should include: careful wound toilet, appropriate excision of damaged tissues, careful wound repair with adequate drainage and systematic therapy with selected antibiotics.	1977	556659
[lupins - a new source of food for andean countries. 5. traditional methods of debittering of lupins by water].	the bitter taste of lupin alkaloids can be sensorially detected in water within ppm-range. the strength of the taste diminishes as follows: sparteine, d-lupanin-perchlorate, lupinine, isolupinine and hydroxylupanine. the swelling capacity of lupin seeds presents different characteristics according to the species. the swelling rapidity is in l. albus somehow inferior to that of l. mutabilis. the absorption of water decreases in hot water, and the swelling rapidity increases. for domestic debitter ...	2005	556411
influence of preoperative left ventricular function on results of homograft replacement of the aortic valve for aortic regurgitation.	the effect of preoperative left ventricular function on eraly and late prognosis was assessed in 69 patients with aortic regurgitation who underwent homograft replacement of the aortic valve. patients were divided into two groups: group a (38 patients) had an ejection fraction of 0.46 or more and group b (31 patients) had an ejection fraction of 0.45 or less. clinical data, hemodynamic data, and operative results were compared in the two groups. in group a there was one early death (2.6%) and th ...	2005	556399
studies on the inhibitory effects of zinc heptanoate on microorganisms.	inhibitory effect of zinc heptanoate was observed on different cultures of bacteria and fungi. growth of all the bacteria was inhibited by the compound. greatest inhibition was seen in the case of staphylococcus albus, streptococcus pyogenes, shigella dysenteriae, shigella sonnei, shigella flexneri, salmonella typhi, s. paratyphi a, s. paratyphi b, vibrio cholerae, corynebacterium diphtheriae, and e. coli whereas least inhibition was found in the case of staphylococcus aureus. in triethanolamine ...	1979	553835
[naevobasaliomatosis (gorlin-goltz syndrome)].		2005	551607
postnatal behavioral changes in prenatally irradiated rats.	rats were exposed on gestational day 15 to 125 r x-irradiation, a treatment known to severely alter brain morphology. at 4-6 weeks of age the behavior of these animals was studied using two methods: (1) measurement of circadian locomotor activity, (2) photographic analysis of behavioral acts. the circadian locomotor activity of irradiated rats was similar to that of controls tested individually or as groups in a residential unit. after morphine sulfate, 2 mg/kg, the increase in locomotor activit ...	1979	551312
aspartame: assessment of developmental psychotoxicity of a new artificial sweetener.		1979	551307
construction of haloaromatics utilising bacteria.		1979	551259
time in chemo-immunotherapy models: an absolute or a relative variable? lessons from the levamisole experience.	an analysis is presented of the findings from the available studies in several cancer models, where 2.5-20 mg/kg levamisole was given in combination with different types of cytostatic drugs. it appears that in chemo-immunotherapy experiments it may be preferable to measure time variables (increase in life span, timing of chemotherapy and of immunotherapy) as a per cent of the median survival time of the untreated controls instead of using time as an absolute measure (in days). as regards the stu ...	1980	551097
morphometric analysis of the loss of chief and parietal cells after partial gastrectomy for duodenal ulcer.	relative chief and parietal cell volume densities were estimated morphometrically in the remnant mucosa of 98 male patients ("series"), operated on for duodenal ulcer by the billroth ii, and in the body mucosa of 55 subjects, age and sex matched, from a random series of a finnish population ("controls"). the relative volumes of chief and parietal cells were significantly lower in the series than in the controls. the mean chief cell: parietal cell ratio was significantly higher in the series than ...	2005	549432
[electron microscopical evidence of spiroplasma citri in nucleus of infected testplants (author's transl)].	this is the first report for the evidence of mycoplasmas in an organelle of a plant cell. spiroplasma citri was detected by electron microscopy in the nucleus of a phloem parenchyma cell of chrysanthemum carinatum schousboe plants, inoculated experimentally by euscelis plebejus fall.	1979	549392
[new trends in maternal and child health].		2005	549247
lymphocyte markers and circulating immune complexes in primary glomerulonephritis.		2005	549018
[ventricular rhythms in acute myocardial infarct].		2005	548111
[possibilities and effects of breast reconstruction after breast cancer. experiences at the institute goustave-roussy].		2005	547841
galactography.	galactography is a quick effective means of evaluating nipple discharge. it is especially indicated when the effluent is bloody. a description of the procedure is discussed. the radiographic findings in both normal and abnormal studies are presented. abnormal findings include filling defects, duct cut-off, duct encasement, extravasation, and duct ectasia. the radiographic diagnosis corresponded with pathologic findings in 12 of 16 cases (75%), although in two cases no radiographic or pathologic ...	2005	547361
influence of portocaval anastomosis on lipid parameters in patients with alcoholic cirrhosis.	the effect of portocaval shunt operation on lipid metabolism was investigated in 10 patients with alcoholic cirrhosis. portocaval shunt operation resulted in a significant decrease of concentration of total serum cholesterol, total serum triglycerides, ldl cholesterol, vldl cholesterol, vldl triglycerides, and lcat activity. the concentrations of free cholesterol, esterified cholesterol, phospholipids, ldl triglycerides, hdl cholesterol, and hdl triglycerides were unaffected.	2005	547323
[results of 131i-therapy for hyperthyroidism (author's transl)].		2005	547075
[lectins as reagents for the differentiation of serum enzymes. lectins as reagents, i. (author's transl)].	lectins from canavalia ensiformis, phaseolus vulgaris, and triticum vulgare react with arylamidase, alkaline phosphatase, gamma-glutamyltransferase, and cholinesterase of human sera by formation of enzymatically active, mostly insoluble complexes. arylamidase, alkaline phosphatase, and cholinesterase react more intensely in sera of healthy people than in sera of patients with liver and neoplastic diseases. arylesterase is bound to a distinct degree only by concanavalin a. the enzymes mentioned a ...	1979	547035
nctr computer systems designed for toxicologic experimentation. v. post-experiment information system.	the post-experiment information system (peis) is an automated data collection and reporting system composed of three specialized subsystems: pathology, chemistry and microbiology. these subsystems function either independently or collectively to construct and maintain a comprehensive data base of all experimental values derived from, or associated with, an animal carcass. all data are retrievable by the unique carcass identification (cid) number assigned at death, which is the correlative of the ...	2005	547017
correlation between gross observations of tumors and neoplasms diagnosed microscopically in carcinogenesis bioassays in rats.	microscopic diagnoses of spontaneous and induced neoplasms in f344 rats in two carcinogenesis bioassays were correlated with the gross observations made at the time of necropsy. the results for a negative and a positive compound with reference to carcinogenicity, indicate that of the gross descriptions indicative of tumors, 37 percent and 24 percent respectively, were not diagnosed as neoplasms microscopically. however, some of the gross lesions were diagnosed histologically as nonneoplastic les ...	1979	547015