Publications

[on some cases of viral encephalitis observed at the clinique de pediatrie et de pu'ericulture de strasbourg].		1963	14091980
[enteroviruses (poliomyelitis, coxsackie, echo) and diseases of the nervous system. critical review and personal experience].		1963	14091974
[enteroviruses and their clinical aspects].		1963	14090706
[study in tissue culture of the enteroviruses isolated in valencia during 1959, 1960 and 1961].		1963	14086916
congenital anomalies and virus infections.		1963	14085777
photodynamic inactivation of poliovirus.		1963	14081357
the aetiology of respiratory tract infections in military personnel. 5. the recovery of echo 28 from cases with minor respiratory illness.		1963	14080487
"cyclopin": a trypsin sensitive consituent of penicillium cyclopium with antiviral properties.		1963	14076873
identification of coxsackie and echo virus isolates with fluorescent antibody.		1963	14076868
[the clinical aspects of acute gastrointestinal diseases caused by coxsackie group b and echo entero- viruses in young children].		1963	14076836
[on the differential diagnosis of serous (aseptic) meningitis of enterovirus etiology. (on the report of s. e. ganzburg and v. i. freidkov)].		1963	14076822
[clinical aspects of a disease of the nervous system caused by echo type 9 virus].		1963	14076819
studies on the isolation of enterovirus and adenovirus in children in the tokushima area.		1963	14073350
acute transverse myelopathy and echo-2 virus infection.		1963	14072959
a continuing surveillance of enterovirus infections in healthy children in six united states cities. i. viruses isolated during 1960 and 1961.		1963	14071359
cytopathic enteroviruses isolated from sporadic cases of febrile illnesses in children with neurological involvement.		1963	14069806
[effect of respiratory virus infections on the course of gastrointestinal diseases in children].		1963	14069398
echo 11 virus infections associated with exanthems.		1963	14069092
viruses associated with upper respiratory illnesses in adults.		1963	14065948
echo virus type i and aseptic meningitis. report of a case with virus isolation from the cerebrospinal fluid.		1963	14065339
disc method for identification and titration of cytopathic viruses and detection of antibodies resulting from their infection.		1963	14065301
haemagglutination by entero-viruses isolated from cases of fever with or without neurological involvement in children.		1963	14065208
virologic studies on common colds among young adult medical students.		1963	14064942
the echo 28-rhinovirus-coryzavirus (erc) group of viruses.		1963	14064940
the role of enteroviruses in respiratory disease.		1963	14064937
viral respiratory disease in the americas.		1963	14064933
the virus diagnostic laboratory: functions and problems based on three years' experience.		1963	14064717
the ability of inhibitors of viral activity to slow down nonspecific degeneration of monkey kidney cell cultures.		1963	14062340
inhibitors of viral activity from uninfected cultures of stable cell lines.ii. properties of inhibitors.		1963	14062332
clinical findings during an echo virus type 13 endemic infection.		1963	14061914
[profitable use of primary human amnion cell cultures in routine virological studies].		1963	14054757
a comparative study of virus haemagglutinins. the stability of haemagglutinins and red cell receptors to certain physical and chemical treatments.		1963	14053271
isolation of enteric viruses in ontario during 1960-1962.	during the past three years at the central laboratory, ontario department of health, 681 isolations were made in tissue culture from 6822 specimens submitted for virus studies by physicians and hospitals from all over ontario. nearly 74% of the isolates were enteroviruses, approximately 5% adenoviruses and about 1% reoviruses. the remaining 20% are still to be identified.although the bulk of isolations was made during the same three-month period (august, september and october) of each year, the ...	1963	14052975
[facial paralysis in echo virus type 4 infection].		1963	14052137
new viral exanthems (concluded).		1963	14050980
new viral exanthems.		1963	14050973
preparation of primary human amnion cells by pancreatin procedure and their susceptibility to enteroviruses.		1963	14050206
the resistance of a2g mice to myxoviruses.		1963	14050204
[on the virus sensitivity of thyroid cell cultures].		1963	14047075
[the inhibiting effect of interferon prepared with mumps virus inactivated in various cell strains. i].		1963	14044567
studies on mixed infection with poliovirus type 1 and echo virus type 7 in monkeys and cell cultures.		1963	14043546
[on the determinism of interference between enteroviruses].		1963	14041428
aseptic meningitis due to frater type virus in ontario.	during the summer and fall of 1959 and 1960 a virus was isolated on 14 occasions from the stool or cerebrospinal fluid or both of 12 patients with a clinical picture of non-paralytic poliomyelitis or aseptic meningitis. the patients were from eight different localities in ontario. the isolated virus was not neutralized by antisera to any of the known enteroviruses, reoviruses or adenoviruses, nor did antiserum to the isolate neutralize any of these viruses. antiserum to frater virus, however, di ...	1963	14031733
the susceptibility of baboon (papio doguera) kidney cells to human enterviruses.		1962	14030399
susceptibility of baboon (papio doguera) kidney cells to human enteroviruses.		1962	14030398
exanthema subitum a review of 243 cases.		1963	14029959
echo 19 virus infections. clinical and laboratory studies.		1962	14023649
[an epidemic of echo virus type 16 exanthema in a hospital with the statistics of a longitudinal study].		1963	14023493
relationship of cerebrospinal fluid pleocytosis to recovery of echo 9 virus.		1962	14020082
[neurological complications of winter catarrhal processes].		1962	14019283
cystic emphysema in premature infants. a report of an outbreak with the isolation of type 19 echo virus in one case.		1963	14017418
comparative study of the interaction of polyoma and other hemagglutinating viruses with an isolated bovine mucoprotein.		1962	14013894
[enterovirus diseases. considerations on coxsackie virus and echo virus infections].		1962	14013504
[the enteroviruses].		1962	14001109
clinical clues in virus infections.		1963	13995046
differences in the selective virus inhibitory action of 2-(alpha-hydroxybenzyl)-benzimidazole and guanidine hcl.		1962	13990297
fatal illness associated with e.c.h.o. virus type 3 infection.		1963	13987841
[studies on the neutral antibodies of enteroviruses in childhood. 2. distribution of the neutral antibodies of echo virus type 6 in the tokushima region].		1963	13986774
[nonpoliomyelitis enteroviruses isolated in belgium since january 1961].		1963	13981009
variation of dominant types of enteroviruses during a sequence of years.		1963	13979534
reovirus and wound-tumor virus: serological cross reactivity.	reovirus and wound-tumor virus share a common antigen capable of fixing complement. this suggests a relationship between these animal-pathogenic and plant-pathogenic viruses.	1963	13978839
echo virus, type 25, in respiratory illness. case report.		1963	13973793
[attempted classification of an infectious syndrome with 3 elements: eruptive fever, arthromyalgia, lymphocytic meningitis].		1963	13973324
[on an outbreak of aseptic meningitis caused by the echo-13 virus].		1963	13972233
[on virus induced bacterial agglutination].		1962	13970664
[infantile enteritis in an infection with type 22 echo virus].		1963	13966931
susceptibility of baboon (papio doguera) kidney cells to human enteroviruses.		1962	13962019
the susceptibility of baboon (papio doguera) kidney cells to human enterviruses.		1962	13962016
chromatography of ribonucleic acid of high molecular weight isolated from fl cells infected with echo 7 virus.		1963	13960143
exanthema subitum a review of 243 cases.		1963	13958107
studies on echo 4 virus (picornavirus group) and its intracellular development.		1963	13957296
[clinical aspects of winter catarrhal processes].		1962	13956556
[complications of winter catarrhal processes].		1962	13956555
[winter catarrhal processes. general remarks, etiology and physiopathology].		1962	13956554
[therapy of winter catarrhal processes].		1962	13956553
[epidemiology and prevention of invernal catarrhal processes].		1962	13956552
[on the occurrence of a variant of type 25 echo virus].		1963	13953729
[the diagnosis and treatment of coxsackie and echo virus infections].		1963	13952446
base composition of the rna of a reovirus variant.	a variant of reovirus 3, dearing strain, isolated after repeated pdssage of the original dearing virus in l cells, is similar to the parent virus in many ways. it is, however, less sensitive to specific antibodies and metabolic inhibitors, and is released from l cells to a lesser extent than the original virus. calculated as moles per 100 moles of total base in rna, the percentage of guanine is 20.2, adenine, 29.8, cytosine, 21.0, and uracil 29.1. these values closely approximate those reported ...	1963	13948920
[epidemiology of echo virus infections].		1963	13948107
[echo virus infections and their incidence in west germany].		1963	13947648
[hemagglutination by certain types of echo virus. i. study of some properties of hemagglutinins].		1963	13946826
[current advances in studies on the common cold].		1963	13937398
enterovirus infections in toronto during 1962.	of 37 children from toronto and surrounding districts who developed aseptic meningitis during summer 1962, 17 excreted echo 9 virus in feces and/or cerebrospinal fluid, 12 of whom showed rising or elevated echo 9 antibody levels in paired sera. a further two patients yielded echo 14 virus from cerebrospinal fluid, one of whose feces also contained this virus, and both patients showed rising echo 14 antibody titres. morbilliform rashes without rhinitis or conjunctivitis were encountered in three ...	1963	13932159
infections with reoviruses.		1962	13929840
[an endemic due to echo virus 13].		1963	13928270
[study on echo virus 9 infections].	at ste. justine hospital, montreal, during the period 1957-61, echo 9 virus was isolated in 27 cases, in 20 of these during the summer of 1961. all had evidence of meningeal irritation, accompanied by fever and headache. four of the 20 patients diagnosed during the summer of 1961 had convulsions; 12 presented with a rash; and two simulated meningococcemia. of the 27 patients, two were paralyzed and one case was diagnosed as transverse myelitis. echo 9 virus was isolated from stools and from thro ...	1962	13928026
characterization of coxsackievirus b3-caused apoptosis under in vitro conditions.	among several mechanisms of pathogenesis of the frequent and sometimes serious infections with coxsackievirus b3 (cvb3), one detail is apoptosis. recently, a new apoptotic mechanism involving the specific interaction between the capsid protein vp2 of the highly virulent variant cvb3h3 and the proapoptotic host protein siva was identified. the relevance of this observation for virus pathogenicity was shown in a balb/c mouse model using cvb3h3 and the interaction-deficient mutant virus cvb3h310a1. ...	2004	13680215
recombination in circulating enteroviruses.	recombination is a well-known phenomenon for enteroviruses. however, the actual extent of recombination in circulating nonpoliovirus enteroviruses is not known. we have analyzed the phylogenetic relationships in four genome regions, vp1, 2a, 3d, and the 5' nontranslated region (ntr), of 40 enterovirus b strains (coxsackie b viruses and echoviruses) representing 11 serotypes and isolated in 1981 to 2002 in the former soviet union states. in the vp1 region, strains of the same serotype expectedly ...	2003	12970427
molecular analysis of echovirus 13 isolates and aseptic meningitis, spain.	echovirus 13 (ev13), considered rare, was reported worldwide in 2000, mostly related to aseptic meningitis outbreaks. in spain, 135 ev13 isolates were identified. the genetic relationships between 64 representative strains from spain and other reported isolates from the united states, germany, italy, japan, and sweden were described by analyzing the partial sequence of the major capsid protein (vp1) gene. the strains from spain were clearly identified as ev13 (79.5% similarity with the ev13 refe ...	2003	12967490
re-emergence of echovirus type 13 infections in 2002 in yamagata, japan.	to analyze the prevalence of echovirus type 13 (echo13) in yamagata, japan.	2003	12963387
bcl-2 and bcl-xl overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus b3 infection.	coxsackievirus b3, a cytopathic virus in the family picornaviridae, induces degenerative changes in host cell morphology. here we demonstrate cytochrome c release and caspases-2, -3, -6, -7, -8, and -9 processing. enforced bcl-2 and bcl-xl expression markedly reduced release of cytochrome c, presentation of the mitochondrial epitope 7a6, and depressed caspase activation following infection. in comparison, cell death using trail ligand caused caspase-8 processing prior to cytochrome c release and ...	2003	12951029
heparan sulfates and coxsackievirus-adenovirus receptor: each one mediates coxsackievirus b3 pd infection.	amino acid exchanges in the virus capsid protein vp1 allow the coxsackievirus b3 variant pd (cvb3 pd) to replicate in decay accelerating factor (daf)-negative and coxsackievirus-adenovirus receptor (car)-negative cells. this suggests that molecules other than daf and car are involved in attachment of this cvb3 variant to cell surfaces. the observation that productive infection associated with cytopathic effect occurred in chinese hamster ovary (cho-k1) cells, whereas heparinase-treated cho-k1 ce ...	2003	12941917
t cells cause acute immunopathology and are required for long-term survival in mouse adenovirus type 1-induced encephalomyelitis.	infection of adult c57bl/6 (b6) mice with mouse adenovirus type 1 (mav-1) results in dose-dependent encephalomyelitis. utilizing immunodeficient mice, we analyzed the roles of t cells, t-cell subsets, and t-cell-related functions in mav-1-induced encephalomyelitis. t cells, major histocompatibility complex (mhc) class i, and perforin contributed to acute disease signs at 8 days postinfection (p.i.). acute mav-1-induced encephalomyelitis was absent in mice lacking t cells and in mice lacking perf ...	2003	12941916
structure of swine vesicular disease virus: mapping of changes occurring during adaptation of human coxsackie b5 virus to infect swine.	the structure of swine vesicular disease virus (svdv) was solved and refined at a 3.0-a resolution by x-ray crystallography to gain information about the role of sequence changes that occurred as this virus evolved from the parental human pathogen coxsackievirus b5 (cvb5). these amino acid substitutions can be clustered in five distinct regions: (i) the antigenic sites, (ii) the hydrophobic pocket of the vp1 beta-sandwich, (iii) the putative car binding site, (iv) the putative heparan sulfate bi ...	2003	12941886
coxsackie virus b antibodies are increased in hla dr3-mica5.1 positive type 1 diabetes patients in the linköping region of sweden.	type 1 diabetes mellitus (t1dm) is an autoimmune disorder in which genetics and environmental factors play a role. among the environmental factors, viruses (especially coxsackie virus b [cbv]), and among genetic markers, human leukocyte antigen (hla) drb104-dqa10301-dqb10302 (dr4-dq8) and drb103-dqa10501-dqb10201 (dr3-dq2), and major histocompatibility complex class i chain-related gene-a (mica) alleles 5 and 5.1 have been reported to be associated with t1dm in caucasians. sweden ranks thi ...	2003	12941542
characteristics of apoptotic cell death induced by coxsackievirus b in permissive vero cells.	coxsackievirus b (cvb) causes a wide spectrum of human diseases which are closely associated with direct destruction of infected cells. we investigated the morphological and biochemical characteristics of cpes in permissive vero cells caused by different cvb serotypes. regardless of serotype, the infected cells experienced similar degrees of cpes within 24 h postinfection (p.i.). using both hoechst 33342 staining and transmission electron microscopy, we consistently observed morphological proper ...	2003	12931034
coxsackievirus replication and the cell cycle: a potential regulatory mechanism for viral persistence/latency.	coxsackieviruses (cv) are characterized by their ability to cause cytopathic effects in tissue culture and by their capacity to initiate acute disease by inducing apoptosis within targeted organs in vivo. these viruses are considered highly cytolytic, but can establish persistence/latency in susceptible cells, indicating that a regulatory mechanism may exist to shut off viral protein synthesis and replication under certain situations. the persistence of coxsackieviral rna is of particular medica ...	2004	12925877
virus-receptor interactions of coxsackie b viruses and their putative influence on cardiotropism.	specific virus-receptor interactions are important determinants in the pathogenesis of viral infections, influencing the location and initiation of primary infection as well as the viral spread to other target organs in the postviremic phase. coxsackieviruses of group b (cvb) specifically interact with at least two receptor proteins, the coxsackievirus-adenovirus receptor (car) and the decay-accelerating factor (daf), and cause a broad spectrum of diseases, including acute and chronic myocarditi ...	2004	12920584
dystrophin disruption in enterovirus-induced myocarditis and dilated cardiomyopathy: from bench to bedside.	genetic defects of the dystrophin-glycoprotein complex (dgc) cause hereditary dilated cardiomyopathy. enteroviruses can also cause cardiomyopathy and we have previously described a mechanism involved in enterovirus-induced dilated cardiomyopathy: the enteroviral protease 2a directly cleaves dystrophin in the hinge 3 region, leading to functional dystrophin impairment. during infection of mice with coxsackievirus b3, the dgc in the heart is disrupted and the sarcolemmal integrity is lost in virus ...	2004	12920582