Publications

detection of blastocystis hominis by direct microscopy and culture.		1990	2351150
[blastocystis hominis in feces. an assessment of 56 cases].	over a twelve-month period all 3918 stool samples sent to our institute were investigated for blastocystis hominis. this protozoon was detected in 384 samples. the stools of 50 healthy controls were negative. in 56 positive cases detailed clinical information was obtained: 26 of these patients had diarrhea, while only extraintestinal symptoms had been recorded in 10 cases. blood eosinophilia was observed in 8 patients. of 16 specifically treated patients, 10 responded to therapy. although the pa ...	1990	2349459
blastocystis hominis in two children of one family.	two apparently healthy children from the same family were found to have moderate to heavy blastocystis hominis in their stool samples whilst being investigated for intestinal symptoms: sporadic, painless, rectal bleeding in one and persistent diarrhoea in the other. after treatment with metronidazole, they had no further signs, and stool samples became negative. eighteen months later, both were asymptomatic, and stool samples continued to be negative for the parasite.	1990	2333700
infective arthritis due to blastocystis hominis.	a patient with rheumatoid arthritis taking prednisone developed blastocystis hominis acute diarrhoea, which was associated with increased inflammation and effusion of the left knee. b hominis organisms were found in synovial fluid from the left knee. the patient responded dramatically to metronidazole treatment. b hominis may become disseminated in immunosuppressed patients with diarrhoea and may cause infective arthritis.	1990	2322029
epidemiology and pathogenicity of blastocystis hominis.	a prospective study was performed on a large outpatient population to evaluate the epidemiology and pathogenicity of blastocystis hominis. patients with stool specimens positive for b. hominis and negative for other bacterial and parasitic pathogens were sent a questionnaire and were requested to submit a follow-up specimen for ova-and-parasite examination. b. hominis was identified in 530 of 16,545 specimens (3.2%). there was a spectrum of clinical-pathological presentations in the 143 patients ...	1990	2298869
magainin analogs effective against pathogenic protozoa.	the in vitro activities of magainin analogs against blastocystis hominis, entamoeba histolytica, and trypanosoma cruzi were assessed by protozoan morphological integrity and motility. the antiprotozoan activities in descending order were magainin b greater than g greater than h, the same order as the alpha-helix contents of the analogs. magainin b and g were effective against b. hominis, t. cruzi, and e. histolytica.	1990	2285300
potential clinical significance of blastocystis hominis in egypt.		1990	2278075
frequency of recovery of blastocystis hominis in clinical practice.	we examined the frequency of isolation of blastocystis hominis from stools of patients seen in an indigent-care teaching hospital. over a 2-year period, 2,744 stool specimens were examined prospectively. b. hominis was found in 262 stools (9.5% of all stool specimens and 53.5% of the positive specimens). clinical data were obtained from 80 patients with stools positive for b. hominis. b. hominis was the only parasite isolated in 39 of 47 (83%) of the adults, compared with 17 of 33 (52%) of the c ...	1990	2229995
[etiology of diarrheal diseases in immunocompetent and hiv-positive patients].	in 1986 and 1987 the stool samples of 206 patients of the medical outpatient clinic basel were examined prospectively for bacteria, protozoa and worms. clinical data of the patients were recorded by questionnaire. the patient group comprised 63 immunocompetent patients as well as 23 hiv-infected patients, all with symptoms of acute enteritis. the control group consisted of 120 healthy persons. pathogenic organisms were found in the stools of 17.5% of the immunocompetent patients with enteritis. ...	1990	2218447
[blastocystis hominis infection in aids and correlated pathologies].	blastocystis hominis may sometimes be found in feces in sufficient quantities to cause symptoms of diseases such as diarrhea abdominal pain, nausea, tenesmus, fever, itching and slight acidocytosis. three cases of blastocysosis observed in patients with las are reported.	1990	2216046
blastocystis hominis treatable cause of diabetic diarrhea.		1990	2209335
[blastocystis hominis infection frequency: a year of study].	since july 1987 to june 1988, out of a total of 2,009 stool examinations performed at a private laboratory, in barquisimeto, venezuela, we could identify blastocystis hominis in 206 of them, using the methods of wet preparation with s.s.f., iugol and quensel. clinical information was obtained in 73 patients. the group more affected was the one older than 12 years of age. we suggest the investigation and to report b. hominis in the feces test, because in presence of clinic manifestations and abse ...	1990	2152310
blastocystis hominis infection in patients with diabetes mellitus. clinical case history.		1990	2123358
blastocystis hominis infection: signs and symptoms in patients at wilford hall medical center.	blastocystis hominis (b. hominis) is a protozoan that may inhabit the human gastrointestinal tract. in our study we reviewed the signs and symptoms of patients at wilford hall with stool specimens positive for b. hominis. these patients fell into four groups, hiv-positive adults, foreign nationals, children, and adults not known to be hiv positive. b. hominis caused an acute self-limited diarrheal illness, or chronic gastroenteritis with nausea, abdominal pain, and mild diarrhea. metronidazole e ...	1990	2120622
blastocystis hominis: an unusual cause of diarrhoea.		1990	2102207
blastocystis hominis.		1990	2101593
[enterocolitis caused by blastocystis hominis and hiv infection].		1990	2095911
blastocystosis: a new disease in the acquired immunodeficiency syndrome?	the protozoon blastocystis hominis may cause episodes of diarrhoea with abdominal pain, tenesmus, fever and eosinophilia. we have observed 5 cases of blastocystosis in male subjects with symptomatic hiv infection. all patients had a complete response to metronidazole. this report confirms that blastocystis hominis may be responsible for hiv-related diarrhoea.	1990	2092790
[blastocystis hominis in an hiv-positive homosexual patient].		1991	2041894
pathogenicity of blastocystis hominis.		1991	2037690
use of electron microscopy in examination of faeces and rectal and jejunal biopsy specimens.	the stools and rectal biopsy specimens of 44 patients with aids and diarrhoea were examined by culture, light microscopy, and electron microscopy. in 13 patients examination of rectal biopsy material and faecal samples showed no pathogen, but in two of these, microsporidiosis was found by electron microscopical examination of jejunal biopsy specimens. this organism was also identified electron microscopically in one of the further five jejunal biopsy samples taken from patients with a known caus ...	1991	2030151
clinical report of blastocystis hominis infection in children.	during a 9-month hospital-based survey, the intestinal parasite blastocystis hominis was detected in high numbers (five or more organisms per oil immersion field) in faecal specimens from 39 (2%) of 1960 children under 13 years old. abdominal pain or discomfort with or without diarrhoea was present in 32 children categorized as acute (14), subacute (7) or chronic (11) cases with respective mean ages of 6.4, 7.3 and 8.7 years. they included three with other enteropathogens (giardia lamblia, crypt ...	1991	2023289
blastocystis hominis--past and future.	the history of b. hominis is unique. few infectious agents have provoked the many misconceptions that plague this enigmatic parasitic ameba. conflicting descriptions of its nature and pathogenesis have continued throughout the 20th century. as seen by the greatly expanded number of reports in recent years, b. hominis is now a major subject of study, particularly for evidence of disease causation. physicians are treating patients with intestinal disease caused by b. hominis. many mild cases resol ...	1991	2004348
reactive arthritis from blastocystis hominis.		1991	1994931
sds-page and immunological analysis of different axenic blastocystis hominis strains.	consistent major differences were detected by sds-page, western blotting and ouchterlony immunodiffusion in four axenic and microscopically indistinguishable strains of the anaerobic human parasite blastocystis hominis from different sources. it is concluded that at least two variants with different polypeptide patterns and antigens exist and the biological significance of these findings is discussed.	1991	1906543
pathogenicity of blastocystis hominis.		1991	1889876
blastocystis hominis may be a potential cause of intestinal disease.	blastocystis hominis is a common inhabitant of the human bowel. it is now increasingly recognized as a potential cause of diarrhea. this article presents 12 cases of prolonged or recurrent diarrhea associated with b. hominis found in a large number. no other intestinal parasites were recognized. all patients responded to metronidazole. this report confirms that b. hominis may be a cause of intestinal disease.	1991	1882204
the in-vitro activity of drugs against blastocystis hominis.	the development of an assay to measure the sensitivity of drugs against blastocystis hominis using the incorporation of 3h-hypoxanthine is described. the activity of 42 compounds have been measured. four of the 5-nitroimidazoles tested (satranidazole, s75 0400 a, flunidazole and ronidazole) were found to be more active than metronidazole, the drug commonly used to treat infections caused by b. hominis in humans. other potentially useful compounds include emetine, furazolidone and quinacrine. ket ...	1991	1856129
[blastocystis hominis in canavese: a retrospective study of samples received for fecal parasitological examination at the ivrea- castellamonte hospital over 42 months].	in the last ten years the interest in the controversial blastocystis hominis microorganism of the intestine has greatly increased. the authors conducted a retrospective study of feces for parasitology investigations at the ivrea-castellamonte hospital. these investigations lasted 42 months (1/1/1988-31/6/1991) and the authors focused their attention on samples with 5 or more blastocystis hominis at the microscopically examination with a 40x phase objective. during the study 2,138 samples of fece ...	1991	1844921
[blastocystis hominis: frequency of infection in ambulatory patients from the northern section of santiago, chile].	in july 1989-july 1990 period, a coproparasitological study of 6,162 ambulatory patients from the northern section of santiago, was undertaken. out of the total number of the studied individual, 88.6% were children, (51.4% females and 48.6% males). the global frequency of infection by b. hominis was 30.4%. in relation to age. blastocystis hominis was found in: 13.1% of the group of children (1 month-2 years); 34.1% of the pre-school children, 45.4% in the school-children and 43.0% in the adults. ...	1991	1843860
[controversial aspects of blastocystis hominis: taxonomy and emerging concepts of pathogenicity].		1991	1822720
occurrence of blastocystis sp. in pigs.	the occurrence of blastocystis sp. was monitored in pigs of various age from 5 pig farms in southern bohemia. prevalence was determined especially via cultivation in modified nutrient broth les. in sucking pigs up to 2 days old blastocystis sp. was not found; from 3 days blastocystis sp. persists throughout the pig life. in droppings and in cultures there both vacuolar and granular forms were observed. ameboid forms were not found. in culture ultrastructure was observed by transmission electron ...	1991	1822462
ultrastructural evidence for a possible differentiation way in the life-cycle of blastocystis hominis.	the present paper is reporting the characteristic ultrastructural aspects of an amoeboid b. hominis population obtained from a child having giardiasis and dysentery in history. the particular features of smooth endothelial reticulum are postulated as being the expression of functional changes of this organelle in the differentiation process, the protozoon passing from the amoeba to the vacuolar form.	1991	1821165
results of testing for intestinal parasites by state diagnostic laboratories, united states, 1987.	we analyzed results of 216,275 stool specimens examined by the state diagnostic laboratories in 1987; parasites were found in 20.1%. percentages were highest for protozoans: giardia lamblia (7.2%), entamoeba coli and endolimax nana (4.2% each), blastocystis hominis (2.6%), entamoeba histolytica (0.9%), and cryptosporidium species (0.2%). identifications of giardia lamblia increased broadly from the 4.0% average found in 1979, with 40 states reporting increases and seven decreases. most states th ...	1991	1779956
pathogenicity of blastocystis hominis.		1991	1774343
ultrastructure of blastocystis hominis in human stool samples.	a study of the ultrastructure of blastocystis hominis in human stools found morphological differences between the organisms seen and those present in laboratory cultures. b. hominis found in stool samples showed little morphological variation with storage time before fixation, but were consistently smaller (approximately 5 microns in diameter), with a thicker surface coat than the cultured organisms. the large central vacuole, characteristic of the cultured organisms, and accepted as standard mo ...	1991	1774117
blastocystis hominis complicating ulcerative colitis.		1991	1744851
a cyst-like stage of blastocystis hominis.	a cyst-like form of blastocystis hominis is described in stools and in culture. this form is more common in stored stools than fresh material. a cyst wall is secreted under the surface coat of the cell, and the surface coat and cell debris subsequently separate from the cyst. whether this stage can withstand adverse environmental conditions and is infective to a new host remain to be determined.	1991	1743860
longitudinal study of young children in kenya: intestinal parasitic infection with special reference to giardia lamblia, its prevalence, incidence and duration, and its association with diarrhoea and with other parasites.	84 young children from a rural community, nderu, in kenya, were each followed for up to 10 months, from january to november 1987. their ages ranged from 10 to 28 months over the period of study. stools were obtained once a week, as were reports from the mothers about presence of abdominal complaints, including diarrhoea. a total of 2258 stools and 1873 reports were collected. 9 parasites were commonly encountered of which giardia lamblia was the most frequent at 44.7%. the overall estimated numb ...	1991	1686143
clinical significance of blastocystis hominis.		1991	1671956
blastocystis hominis: commensal or pathogen?		1991	1671894
[importance of the diagnosis of blastocystis hominis in the parasitological examination of feces].	feces of 798 male and female patients who attended the parasitology laboratory of the "facultad de ciencias bioquímicas y farmacéuticas de la universidad nacional de rosario (república argentina)" were examined. out of the total number of samples, 281 were collected after a purgative, and 517 by serial collection. the samples were examined applying the routine parasitological analysis. those which presented blastocysts hominis were processed for their quantification and classification in differe ...	1991	1670481
endoscopy of blastocystosis (zierdt-garavelli disease).		1992	1600197
blastocystis hominis in hospital employees.	several reports have appeared that either support or deny the importance of the protozoan blastocystis hominis as an intestinal pathogen in humans. in this report, we describe the clinical characteristics of b. hominis and its response to therapy in hospital employees found to have the parasite on routine screening of stools. during the study, 49 patients with b. hominis were identified, and 413 stools were examined from these patients. twenty-nine patients were asymptomatic (59%), and 20 had sy ...	1992	1590309
protein and dna evidence for two demes of blastocystis hominis from humans.	analysis of 10 stocks of blastocystis hominis isolated from human stools revealed two discrete groups of organisms. proteins of the two groups were immunologically distinct and hybridization with random probes generated from the dna of one stock showed that the dna content of the two groups was different. further studies are required to determine whether these should be classified as discrete species or whether these groups are epidemiologically significant.	1992	1563920
blastocystis hominis: a controversial enteric protozoon.		1992	1556417
identification of blastocystis hominis by colonic brush cytology. a case report.	blastocystis hominis is a unicellular organism the pathogenic potential of which in humans remains unclear. it may be identified during a workup for gastrointestinal symptoms, usually in stool examined for ova and parasites. we describe a case in which b hominis was identified by cytologic examination in a patient with crohn's disease who underwent colonoscopy and brushing of a transverse colon stricture. the morphologic features of this organism are described and contrasted with those of the un ...	1992	1523938
varying incidence of blastocystis hominis in cultures from faeces of patients with diarrhoea and from healthy persons.	a study was performed on the frequency of blastocystis hominis in the faeces from 100 patients suffering from diarrhoea and from 100 healthy persons. surprisingly, an increased detection rate was observed in samples from healthy persons after anaerobic cultivation. this increased frequency is obviously not dependent on the kind of serum used as a culture supplement and raises the question whether the protozoa morphologically described as b. hominis represent a homogenous species. when rabbit and ...	1992	1520961
comparative analysis of lipid composition in axenic strains of blastocystis hominis.	1. six axenic strains of blastocystis hominis varied in content of lipids from 12 to 43 pg total lipid/cell. with all strains, phospholipid content was about 39% of total lipids. 2. neutral lipid fractions of b. hominis were resolved into nine constituents, of which seven were identified tentatively. sterol esters, principally esters of cholesterol, were the major neutral lipid constituent, accounting for 49-63% of the neutral lipids, and at least 30% of the total lipids. 3. polar lipids were re ...	1992	1499298
[blastocystis hominis: in search of a disease, a misunderstood organism].	blastocystis hominis is a micro-organism which remains somewhat mysterious. having defined its present position in the classification of protozoa, the authors describe its ultrastructure and morphology. its epidemiology and pathogenicity are discussed in the light of experimental studies and human clinical data, especially in aids patients. metronidazole seems to be the most active drug against this organism, but extreme caution must be exerted when the possible pathogenic property of b. hominis ...	1992	1480568
[blastocystis hominis].		1992	1450262
cryptosporidiosis among patients with acquired immunodeficiency syndrome in zulia state, venezuela.	we studied the prevalence of cryptosporidium in 29 patients with acquired immunodeficiency syndrome (aids) from zulia state, venezuela. they ranged in age from five months to 46 years. two were children and 27 were adults, of which six were women. of the 21 men, 66.6% reported homosexual behavior. three stool samples from each patient were examined, and modified ziehl-neelsen carbolfuchsin staining of formalinether stool concentrates was used to identify cryptosporidium oocysts. to detect the pr ...	1992	1449198
[blastocystis infection and aids].		1992	1435582
[a survey of intestinal parasites of the foreign laborers (indonesians and filipinos) in ishikawa prefecture].	a survey of intestinal parasites was conducted on 198 foreign workers aged 19-27 from inodonesia and philippines. they work for a private company in ishikawa prefecture as technical trainee. on the base of stool examination, 94 (71%) out of 133 indonesians and 48 (74%) of 65 filipinos had intestinal helminths and/or protozoan infections. the prevalence of ascaris lumbricoides, trichuris trichura and hookworm was 4.5, 64.1, 10.6%, respectively. in addition, the positive rate of the cyst of entamo ...	1992	1431385
epidemiology of blastocystis hominis infection in papua new guinea: age-prevalence and associations with other parasites.	a community-based study of blastocystis and other intestinal parasites in the asaro valley, papua new guinea showed an extraordinary high prevalence and variety of protozoan infections. apart from infants, nearly everybody had at least one infection, and the mean number of infections per person was around 2.7. the graph of age-specific prevalence for blastocystis is similar in shape to those for entamoeba coli and endolimax nana, indicating probable similarity in transmission patterns and host r ...	1992	1417203
epidemiology and clinical significance of blastocystis hominis in different population groups in salamanca (spain).	a prospective study was carried out to investigate the epidemiology and clinical significance of blastocystis hominis in the following groups of the population of the city of salamanca (spain): in children attending 11 day care centres and 7 primary schools, two fecal samples were obtained from each child, and in 1231 patients attending the clinical hospital. a b. hominis incidence of 5.3-10.3% was found in the day care centres and an incidence rate of 13.4-19.4% was found in the primary schools ...	1992	1397225
comparative aetiology of childhood diarrhoea in kakamega and kiambu districts, kenya.	two hundred diarrhoea specimens collected during january to february 1988, from rural children aged 0 to 60 months in kakamega district were examined for bacteria, parasites and rotavirus. the results were compared with a sample of 184 diarrhoea specimens matched for month of collection, taken from data collected in the same manner from children in kiambu district. the mean ages of children in the 2 samples did not differ significantly. there were significant differences in the prevalence of spe ...	1992	1396210
absence of an association between enteric parasites in the manifestations and pathogenesis of hiv enteropathy in gay men. the gi/hiv study group.	49 gay men confirmed to be infected with the human immunodeficiency virus (hiv) and 9 hiv seronegative gay men participated in a pilot study comparing clinical status and enteric parasite load with gastrointestinal structure, function and symptomatology. cases included 16/49 (33%) men who were cdc stage ii, 7/49 (14%) who were cdc stage iii, and 26/49 (53%) who were cdc stage iv. the mean cd4-lymphocyte count was 476 +/- 199 (sd)/microliter. the prevalence of enteric parasitic flora was similar ...	1992	1361241
effect of co-trimoxazole on stool recovery of blastocystis hominis.		1992	1346686
[blastocystosis and other intestinal protozoan infections in human riverside communities of the valdivia river basin, chile].	between march and october 1987, the prevalence of infection by blastocystis hominis and other intestinal protozoan, their relationship with the age and sex of the hosts, and the percentage of infected persons in family groups were determined in riverside communities of valdivia river basin, chile. one or more intestinal protozoan species were determined in 72.5% of the examined persons. the prevalence was greater for b. hominis (61.8%). the prevalences of b. hominis, endolimax nana and entamoeba ...	1992	1342125
persistent diarrhoea and blastocystis hominis.		1992	1321538
intestinal protozoan infections in malaysia.	intestinal protozoa are found in all communities in malaysia and among all ethnic groups. prevalence of intestinal protozoa is not affected by ethnicity but by living conditions. communities with both basic amenities of safe water supply and proper toilets have lower prevalence than those with one or none of the amenity. cryptosporidium is an important intestinal protozoon in malaysia and should be included in future field and laboratory studies and also in laboratory diagnosis for pathogens. mu ...	1992	1298065
gastroenteritis outbreak at an industrial camp--british columbia.		1992	1291017
endosymbiosis in blastocystis hominis.		1976	1269586
blastocystis hominis: pathogenic potential in human patients and in gnotobiotes.		1976	1269579
massive development of amebas in the large intestine. fedor aleksandrovich lesh (lösch).	fedor aleksandrovich lesh (lösch) 1840-1903. although lösch was a distinguished russian physician, little has been written about him in english. a graduate of the medico-chirurgical academy in st. petersburg (1863), he defended a doctoral thesis on pulmonary embolism and infarction in 1866, and became an assistant professor of medicine in 1871. from 1872 to 1885 he was a lecturer on diagnosis at the women's medical college and a consultant to the nikolayev military hospital. in 1885 he became pr ...	1975	1098489
ultrastructure and light microscope appearance of blastocystis hominis in a patient with enteric disease.	the patient reported had a fulminant, refractory diarrhea of unknown etiology producing about 81 of diarrheal fluid daily which required continuously large volumes of intravenous fluid therapy. no protozoon other than blastocystis hominis was present. bacterial counts were very low in the fecal material because of continuous antibiotic therapy. blastocystis hominis was present in large numbers, averaging for a 5-day period, 8.3 x 10(6)/ml of diarrheal fluid. treatment with metronidazole for 12 d ...	1976	997721
blastocystis hominis in the liver of cricetus auratus.		1977	603382
contributions to blastocystis hominis studies. aspects of degenerescence.		1979	575709