Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [verminous bronchopulmonitis due to nematoda in a phoca vitulina]. | 2003 | 5152950 | |
| malignant leukemic lymphoma in two harbor seals (phoca vitulina geronimensis). | 1971 | 5103653 | |
| comparison of myoglobins from harbor seal, porpoise, and sperm whale. vii. mechanism and catalysis for addition of cyanide to myoglobins. | 1971 | 5102925 | |
| diffuse muscular degeneration in captive harbor seals. | 1972 | 5056186 | |
| the harbor seal phoca vitulina concolor de kay: comparative details of fatty acids in lung and heart phospholipids and triglycerides. | 1972 | 5050940 | |
| factors related to the dive reflex in harbor seals: sensory contributions from the trigeminal region. | 1974 | 4838186 | |
| factors related to the dive reflex in harbor seals: respiration, immersion bradycardia, and lability of the heart rate. | 1974 | 4838185 | |
| eimeria phocae sp. n. from the harbor seal (phoca vitulina concolor). | 1974 | 4833850 | |
| coccidiosis in harbor seals. | 2016 | 4817958 | |
| cerebral tolerance to asphyxial hypoxia in the harbor seal. | 1973 | 4763083 | |
| heart rate during breath-holding and diving in the unrestrained harbor seal (phoco vitulina richardi). | 2016 | 4756147 | |
| inhaled co2 and progressive hypoxia: ventilatory response in a yearling and a newborn harbor seal. | 1973 | 4731025 | |
| oxygen uptake of the california sea lion and harbor seal during exposure to heat. | 1973 | 4726508 | |
| staphylococcal infection and toxoplasmosis in a young harbor seal. | 1973 | 4716215 | |
| observations on the breeding behavior of the harbor seal in the state of washington. | 1973 | 4706261 | |
| comparison of carboxymethylation patterns of harbor seal and sperm whale myoglobins. | 1973 | 4702882 | |
| adaptations in the breeding of the harbour seal, phoca vitulina. | 1973 | 4522368 | |
| directional hearing of a harbor seal in air and water. | 1974 | 4443485 | |
| renal recovery from ischemia: a comparative study of harbor seal and dog kidneys. | 1974 | 4440777 | |
| cation transport and energy metabolism in the high na+, low k+ erythrocyte of the harbor seal, phoca vitulina. | 1971 | 4398992 | |
| pox in young, captive harbor seals. | 1972 | 4341394 | |
| the lipid composition of the blood of marine mammals. ii. atlantic bottlenose dolphins, tursiops truncatus and two species of seals, halichoerus grypus and phoca vitulina. | 1971 | 4330449 | |
| ddt plus pcb's in blubber of harbor seals. | 1974 | 4216002 | |
| evaporative heat loss in the california sea lion and harbor seal. | 1974 | 4151637 | |
| conductive heat loss to sand in california sea lions and a harbor seal. | 1974 | 4149005 | |
| coronary blood flow and myocardial segment dimensions during simulated dives in seals. | three harbor seals phoca vitulina richardsi and five spotted seals phoca vitulina largha were used in studies of acute episodes of local myocardial ischemia in open-chest, anesthetized animals and of coronary blood flow and regional function as indicated by left ventricular segment dimensions during experimentally simulated dives of conscious, instrumented animals. we observed that seal myocardium, in which there are few coronary anastomoses, responded to brief local occlusion with prompt local ... | 1985 | 4073282 |
| the isolation and partial characterization of a highly pathogenic herpesvirus from the harbor seal (phoca vitulina). | this report describes the first isolation and partial characterization of a herpesvirus from the harbor seal (phoca vitulina). the virus was isolated during a disease outbreak in a group of young seals nursed in a seal orphanage in the netherlands. almost half of the seals died with symptoms of acute pneumonia and focal hepatitis and the virus was isolated of organs of most of the dead animals. seven out of ten seals of which paired serum samples were obtained showed seroconversion in a virus ne ... | 1985 | 4062560 |
| [measurement of oxygen consumption and external respiratory parameters in seals (phoca vitulina) swimming freely in a pool]. | 1985 | 3996670 | |
| amino-acid sequence of the alpha and beta chains of adult hemoglobin of the harbor seal, phoca vitulina. | the complete amino-acid sequences of the alpha and beta chains of adult hemoglobin of harbor seal, phoca vitulina that belong to carnivora were determined as follows. the alpha and beta chains isolated by chromatography on a cm-cellulose column were digested with trypsin after s-carboxymethylation. amino-acid sequences of the tryptic peptides derived from both chains were analysed. comparing the primary structures of the alpha and beta chains of the seal hemoglobin with those of human, dog, bear ... | 1986 | 3828075 |
| reproductive failure in common seals feeding on fish from polluted coastal waters. | the population of common seal phoca vitulina in the westernmost part of the wadden sea, the netherlands, has collapsed during the past few decades. between 1950 and 1975 the population dropped from more than 3,000 to less than 500 animals. comparative studies of common seal populations from different parts of the wadden sea reveal that pup production has declined sharply only in the western (dutch) part. a comparative toxicological study on the levels of heavy metals and organochlorines in tissu ... | 2013 | 3785423 |
| the relationship of the increased level of metallothionein with heavy metal levels in the tissue of the harbor seal (phoca vitulina). | the relationship between age, heavy metal levels, and a heavy-metal binding protein, metallothionein (mt), in the liver and kidney of the harbor seal (phoca vitulina) was studied. the cadmium (cd) level in the liver and the cd, inorganic mercury (i-hg), and zinc (zn) levels in the kidney were increased with body length, suggesting an age-related accumulation of these metals. the mt levels determined by an mt radioimmunoassay showed concentrations of 240 +/- 139 micrograms/g in the liver and 343 ... | 1986 | 3757869 |
| the lipid composition of serum lipoproteins in the harbour seal, phoca vitulina. | the density profile of serum lipoproteins and their lipid composition was studied in 12 adult, female harbour seals. the animals were sampled after an approximate 20 hr fast. the density profile of lipoproteins showed that the harbour seals displayed a distinct vldl (density less than 1.006 g/ml) and hdl band (density about 1.125 g/ml), but no clear ldl band. there was a rather diffuse population of lipoproteins in the density range of 1.019-1.100 g/ml. mean serum total cholesterol concentration ... | 1986 | 3757483 |
| pressure-volume characteristics of aortas of harbor and weddell seals. | the mechanical properties of the radially enlarged proximal segment of the aorta of diving marine mammals was studied on 15 excised aortas of harbor seals and five aortas of weddell seals. this was done by recording static pressure-volume relationships for the whole thoracic aorta, the aortic bulb, and the descending thoracic aorta and passive length-tension measurements of aortic strips. aortic bulb volume distensibility was found to be much greater than that of the descending thoracic aorta or ... | 1986 | 3728706 |
| survival of neonatal harbor seals. | 1987 | 3570914 | |
| the carotid body of the harbour seal (phoca vitulina richardsi). | the bilateral distribution of carotid body type 1 and 11 cells was investigated in five harbour seals (phoca vitulina richardsi), by serially sectioning the carotid bifurcation regions. the cells occurred bilaterally in the animals and were also present in one specimen from a sixth animal available for study. the type 1 and 11 cells were located in the space between the internal and external carotid arteries and had a varied relationship to the occipital and condyloid arteries. they lay within a ... | 1986 | 3532866 |
| survival versus nonsurvival determinants for neonatal harbor seals. | of 29 neonatal harbor seals that had been abandoned, separated from their mothers, or stranded in the wild, 22 succumbed during hospitalization at the california marine mammal center in the spring of 1982. compared with standard reported harbor seal pup measurements, 8 of the nonsurviving pups were premature (ie, creamy-white lanugo coat, early pupping season birthdate, and decreased body size [6 to 10 cm shorter and 2.3 to 4.5 kg less than normal]). the premature pups and the young pups (less t ... | 1986 | 3505918 |
| capillary configuration in contracted muscles: comparative aspects. | we compared the degree of orientation (anisotropy) of capillaries in skeletal muscles of animals with large differences in oxygen needs and/or tolerance to hypoxia (mammals of different size; reptiles; birds; mammals native to high altitude; diving mammals). in terrestrial mammals, we found a substantial increase in capillary tortuosity with fiber shortening, in muscles with large differences in capillary density (capillary counts/fiber mm2 in transverse sections ranging 450-4350). there was no ... | 1988 | 3381698 |
| distemper-like disease in harbor seals: virus isolation, further pathologic and serologic findings. | 1988 | 3218398 | |
| carnivora: the primary structure of the common otter (lutra lutra, mustelidae) hemoglobin. | the hemoglobin of the common otter (lutra lutra, carnivora) contains only one component. the complete primary structures of the alpha- and beta-chains are presented. they were separated by high-performance liquid chromatography and the sequences determined by automatic liquid and gas-phase edman degradation of the chains and their tryptic peptides. the alpha-chains show 18 and the beta-chains 13 substitutions compared to human alpha- and beta-chains, respectively. in the alpha-chains one heme- a ... | 1988 | 3166739 |
| an outbreak of a herpesvirus infection in harbor seals (phoca vitulina). | during an outbreak of a herpesvirus infection in juvenile harbor seals, 11 out of 23 seals died. the duration of the disease in these 11 animals varied from 1-6 days. nasal discharge, inflammation of the oral mucosa, vomiting, diarrhea and fever up to 40 degrees c were observed in the first days of the disease. in later stages coughing, anorexia and lethargy occurred. severe necrosis of the liver and interstitial pneumonia were the most striking histopathological findings. | 1986 | 3005664 |
| mixed function oxidase activity in the harbour seal (phoca vitulina) from sable is., n.s. | one adult male, eight pups (including two full term foetuses) and nine adult female harbour seals (phoca vitulina) were analysed for indices of mixed function oxidase (mfo) activity. mfo activity was present in liver samples, but was at or below detection limits in samples of kidney, lung and pancreas. hepatic ethoxyresorufin o-de-ethylase and benzo[a]pyrene hydroxylase activities were similar to those reported in other seals and in other mammals. cytochromes p-450 and b5 concentrations were sli ... | 1986 | 2877778 |
| separation and characterization of metallothionein in two species of seals by high performance liquid chromatography-atomic absorption spectrophotometry. | metallothionein (mt) was separated from the livers of two species of seals, ribbon seal (histriophoca fasciata) and harbour seal (phoca vitulina), by high performance liquid chromatography--atomic absorption spectrophotometry (hplc-aas). both gel permeation and anion-exchange hplc demonstrated that mt was present as a mixture of at least two isoforms in the livers of both species of seals. | 1985 | 2866896 |
| mortality of harbor seal pups at different sites in the inland waters of washington. | we examined the mortality rates and causes of death of harbor seal (phoca vitulina) pups in three regions of the inland waters of washington (usa) in 1984. one hundred eight pups were collected during 239 searches of the shoreline areas near harbor seal haulout sites or through public reports. minimum neonatal (up to 1 mo after birth) mortality rates at these regions ranged from 12% to 26% of the pups born. neonatal mortality was highest in the strait of juan de fuca; 33 of the estimated 105 (31 ... | 1989 | 2761005 |
| blood viscosity in phocid seals: possible adaptations to diving. | 1. mean corpuscular volume (mcv) and mean corpuscular hemoglobin concentration (mchc) of phocid seal red blood cells (rbc) are elevated compared to those of most terrestrial mammalian species. the influence of these characteristics on blood flow was revealed by viscosity (vis) measurements. 2. rbc morphology and vis of whole blood from 7 harbor seals and 5 northern elephant seals were compared with blood of the domestic pig. samples were analysed for rbc count, white blood cell (wbc) count, tota ... | 1989 | 2760283 |
| body size and organ accumulation of mercury and selenium in young harbor seals (phoca vitulina). | 1989 | 2713523 | |
| carnivora: the primary structure of the pacific walrus (odobenus rosmarus divergens, pinnipedia) hemoglobin. | the primary structure of the alpha- and beta-chains of the hemoglobin from the pacific walrus (odobenus rosmarus divergens, pinnipedia) is presented. sequence analysis revealed only one hemoglobin component whereas two bands were found in polyacrylamide gel electrophoresis. the globin chains were separated by high-performance liquid chromatography and the sequences determined by automatic liquid- and gas-phase sequencing of the chains and their tryptic peptides. the alpha-chains show 20 and the ... | 1989 | 2706084 |
| infection studies in mink with seal-derived morbillivirus. | morbillivirus derived from diseased harbour seals (phoca vitulina) has characteristics of acute virulent canine distemper virus infection in mink. the infection induced a disease resembling the acute systemic and nervous form of canine distemper. | 1989 | 2669686 |
| histopathologic and immunocytochemical studies of distemper in seals. | thousands of harbor seals (phoca vitulina) died in european seas during 1988. respiratory distress and oculonasal discharge were common clinical signs. we necropsied 76 affected seals. the main necropsy finding was severe pneumonia. microscopic lung changes were characterized by proliferation of type ii pneumocytes, filling of alveolar lumina with serofibrinous exudate, leukocytes, and macrophages, and necrosis of bronchial and bronchiolar epithelium. intracytoplasmic and intranuclear acidophili ... | 1989 | 2652873 |
| sensory function in the harbor seal. | 1989 | 2648566 | |
| morbillivirus infection among seals (phoca vitulina) during the 1988 epidemic in the bay of heligoland. ii. serogological investigations reflecting a previous phocine distemper epidemic in a seal orphanage. | of 57 seals hospitalized in the norddeich orphanage, 37 (65%) had died until 22nd of august, 1988, when the first collection of blood samples from the survivors commenced. all the sera including those obtained at a later date from the remaining animals had invariably higher neutralizing antibody titres against a phocine distemper virus (pdv) isolate than against canine distemper virus (cdv). the difference of mean titres was calculated to be more than 1.5 x log10 serum dilution. peak titres demo ... | 1989 | 2609807 |
| vaccination of harbour seals (phoca vitulina) against phocid distemper with two different inactivated canine distemper virus (cdv) vaccines. | two inactivated canine distemper virus (cdv) vaccines--an adjuvanted whole inactivated virus and a subunit iscom preparation--were tested for their ability to induce protective immunity in harbour seals (phoca vitulina) against phocid distemper, a disease that recently killed greater than 17,000 harbour seals in the north and baltic seas, and was shown to be caused by infection with a newly discovered morbillivirus, which is antigenically closely related to cdv. four cdv seronegative harbour sea ... | 1989 | 2609727 |
| a morbillivirus causing mass mortality in seals. | during an outbreak of a serious apparently infectious disease among harbour seals (phoca vitulina), which started in the kattegat area in april 1988 and rapidly spread to the north sea, the wadden sea and the baltic sea, greater than 17,000 animals died within a period of eight months. in august 1988 it was realized that the clinical symptoms and pathological lesions were similar to those found in canine distemper: apart from general depression and fever, the animals suffered from severe respira ... | 1989 | 2609721 |
| morbillivirus infection of seals (phoca vitulina) during the 1988 epidemic in the bay of heligoland. i. mode, frequency and significance of cultural virus isolation and neutralizing antibody detection. | from 16 (14%) out of 112 dead or euthanized seals originating from wildlife and seal orphanages phocine morbillivirus was isolated. the majority of viral isolates in cell cultures was obtained from lung homogenates of 15 out of 71 free-ranging seals (21%). the virus was isolated by longterm cultivation in roller cultures of seal kidney cells. the phocine morbillivirus was detected by typical cytopathogenic alteration and by peroxidase-linked antibody (pla) assay, respectively. a neutralization t ... | 1989 | 2596201 |
| herpesvirus in harbour seals (phoca vitulina): transmission in homologous host. | in the norddeich orphanage seals about four to five months of age were exposed intranasally and by contact to a phocine herpesvirus which originated from a young seal in this station. virus excretion by the nasal route was observed in two animals on day 2 and 15 post inoculation, respectively. production of neutralizing antibodies was detected one week after exposure. the antibody titre range was approximately tenfold higher in the inoculated seals than in animals of the contact group. the seals ... | 1989 | 2558468 |
| herpesvirus in harbour seals (phoca vitulina): isolation, partial characterization and distribution. | from post-mortem material (liver and lung) and leucocytes of four (3.6%) out of 112 examined harbour seals during the seal epizootic in 1988 six cytopathogenic viral isolates were obtained which were provisionally classified as herpes-like viruses. results of physico-chemical and electron microscopic investigations suggested their relationship to the herpesvirus family. serological examinations were carried out with sera from wildlife as well as captive animals using herpesvirus isolates from fo ... | 1989 | 2558467 |
| mechanism of tolerance to renal ischemia in harbor seal: role of membranes. | many diving animals are capable of engaging in long breath-hold dives. investigations were undertaken to compare the active tubular transport of organic ions between kidney slices from harbor seals (phoca vitulina) and rats (control) under anoxia or low ph or both. para-aminohippurate (pah) and tetraethylammonium (tea) were used as a representative organic anion and cation, respectively. the slice-to-medium concentration ratios (s:m) of pah (congruent to 2.5) in the harbor seal was not altered ( ... | 1989 | 2552633 |
| humoral immune responses in seals infected by phocine distemper virus. | recently the isolation and characterisation of a morbillivirus which caused high mortality in common seals (phoca vitulina) in 1988 have been reported. because of the clinical and pathological similarity of the disease in seals to that of distemper in dogs, the name phocine distemper virus (pdv) has been proposed. there are marked differences in the virus-induced proteins of pdv compared to other morbilliviruses and the humoral immune response of moribund and dead seals to pdv was restricted to ... | 1990 | 2382048 |
| histopathological findings in harbour seals (phoca vitulina) found dead on the german north sea coast. | various organs--lung, trachea, liver, kidney, heart, adrenal gland, skin, spleen, thymus, lymph node, gut, thyroid, spinal cord and brain--were removed from 43 seals at dissections performed on the german north sea coast. the specimens were fixed in formalin and routinely processed for light microscopy. the major pathological findings were lung: acute congestion with interstitial and intra-alveolar oedema; intra-alveolar haemorrhage; suppurative bronchitis and bronchopneumonia; larvae and adult ... | 1990 | 2365846 |
| temperature and the oxygen-hemoglobin dissociation curve of the harbor seal, phoca vitulina. | to determine the effect of temperature and ph on oxygen-hemoglobin affinity of the harbor seal, we measured 61 biotonometric oxygen-hemoglobin dissociation curves on blood from 5 seals at 3 temperatures and a range of ph values. the average (+/- sem) hemoglobin concentration was 3.44 +/- 0.15 mm, nearly 50% greater than found in normal humans. at ph 7.4 the p50 (partial pressure of o2 at 50% hemoglobin saturation) +/- sem values were 22.4 +/- 0.6,25.3 +/- 0.5, and 28.5 +/- 0.4 torr at 33, 37 and ... | 1990 | 2336490 |
| a review of the 1988 european seal morbillivirus epizootic. | an epizootic of morbillivirus infection killed thousands of common seals (phoca vitulina) in european seas in 1988. most of the affected seals had respiratory signs and the main post mortem finding was acute pneumonia. the histopathological changes were similar to those of canine distemper. six common porpoises (phocoena phocoena) found stranded on the coast of northern ireland in late 1988 had similar lesions. morbillivirus infection also killed several thousand siberian seals (phoca siberica) ... | 1990 | 2288059 |
| morbillivirus infections of seals during the 1988 epidemic in the bay of heligoland: iii. transmission studies of cell culture-propagated phocine distemper virus in harbour seals (phoca vitulina) and a grey seal (halichoerus grypus): clinical, virological and serological results. | eight harbour seals (phoca vitulina), two of them seronegative, six seropositive against pdv and a seronegative grey seal (halichoerus grypus) were exposed to a low doses of a cell culture-propagated phocine distemper virus isolate (pdv 2558/han 88). an intranasal route of inoculation was chosen. clinical signs, resembling those of 1988's seal disease and seroconversion were observed in both seronegative harbour seals. one of them succumbed to the infection. the virus was not transmitted to anot ... | 1990 | 2267888 |
| progesterone and oestradiol-17 beta concentration profiles throughout the reproductive cycle in harbour seals (phoca vitulina). | serum samples of harbour seals kept in captivity were analysed for progesterone and oestradiol-17 beta. the hormone profiles obtained were used to describe a complete reproductive cycle. a clear peak in oestradiol values, indicative of ovulation, was followed by elevated concentrations of progesterone. implantation probably occurred 3-3.5 months thereafter. progesterone concentrations rose significantly in the last 3-4 months of gestation, whereas oestradiol concentrations gradually increased af ... | 1990 | 2250239 |
| responses of harbor seal and pig heart to progressive and acute hypoxia. | myocardial oxidative and glycolytic reserves were evaluated in four harbor seals, phoca vitulina richardsi, and six domestic pigs, sus scrofa (hematocrits: 58 +/- 5 and 34 +/- 1%., respectively). progressive hypoxia was induced by lowering arterial hemoglobin-oxygen saturation in 10% decrements, each maintained for 10-min periods, until the onset of heart failure. myocardial oxygen consumption rate (vo2), lactate release/uptake rate (l), and triple product, an index of myocardial energetic deman ... | 1990 | 2221153 |
| mass mortality in seals caused by a newly discovered morbillivirus. | during a recent disease outbreak among harbour seals (phoca vitulina) in the north and baltic seas, more than 17,000 animals have died. the clinical symptoms and pathological findings were similar to those of distemper in dogs. based on a seroepizootiological study, using a canine distemper virus (cdv) neutralization assay, it was shown that cdv or a closely related morbillivirus (phocid distemper virus-pdv) was the primary cause of the disease. the virus was isolated in cell culture from the or ... | 1990 | 2205971 |
| comparison of two morbilliviruses isolated from seals during outbreaks of distemper in north west europe and siberia. | recently morbilliviruses were isolated from harbour seals (phoca vitulina) in north west europe (phocid distemper virus-1: pdv-1) and from baikal seals (phoca sibirica) in siberia (phocid distemper virus-2: pdv-2) during outbreaks of severe disease which resembled distemper in dogs. pdv-1 and pdv-2 were passaged in spf dogs, in which they caused distemper-like disease symptoms, and were subsequently passaged in vero cells in which they caused cytopathic changes. pdv-1, pdv-2, and canine distempe ... | 1990 | 2141248 |
| cardiac output and stroke volume in swimming harbor seals. | cardiac output was measured by the thermodilution method in three young harbor seals, at rest and while swimming up to the maximum effort for which they could be trained. stroke volume was determined by counting heart rate simultaneously with determination of cardiac output. cardiac outputs varied widely between surface breathing (7.8 ml.kg-1.s-1) and breath-holding while swimming under water (1.8 ml.kg-1.s-1). stroke volume while at the surface was almost twice the volume while submerged. surfa ... | 1990 | 2097298 |
| rearing and rehabilitation of common seal pups (phoca vitulina). | veterinary surgeons may be presented with seal pups that require rearing and rehabilitation. this paper describes the feeding, weight gains and clinical care of 22 harbour or common seal pups (phoca vitulina) that were reared and rehabilitated at the rspca seal assessment unit in norfolk during 1989. eighteen of the seals survived and were released but four died. on arrival the pups' mean (+/- sd) bodyweight was 9.2 +/- 2.1 kg; those which survived stayed an average of 14.2 +/- 2.3 weeks before ... | 2004 | 2089774 |
| [structure of the endotheliocytes of cerebral vessels of aquatic mammals]. | by means of scanning microscopy the relief of luminal surface of endotheliocytes, lining microvessels of various parts of the brain in the pusa sibirica, phoca vitulina and delphinapterus leucas have been studied. specialized formations of the cellular surface--various processes, projections, toruli have been revealed; their character in various parts of the brain in diving animals is determined by the blood stream conditions and their different sensitivity to oxygen deficiency during diving. th ... | 1991 | 2053874 |
| the effect of submergence on heart rate and oxygen consumption of swimming seals and sea lions. | respiratory, metabolic, and cardiovascular responses to swimming were examined in two species of pinniped, the harbor seal (phoca vitulina) and the california sea lion (zalophus californianus). 1. harbor seals remained submerged for 82-92% of the time at swimming speeds below 1.2 m.s-1. at higher speeds, including simulated speeds above 1.4 m.s-1, the percentage of time spent submerged decreased, and was inversely related to body weight. in contrast, the percentage of time spent submerged did no ... | 1991 | 2045544 |
| fuel homeostasis in the harbor seal during submerged swimming. | 1. the turnover rates and oxidation rates of plasma glucose, lactate, and free fatty acids (ffa) were measured in three harbor seals (average mass = 40 kg) at rest or during voluntary submerged swimming in a water flume at 35% (1.3 m.s-1) and 50% (2 m.s-1) of maximum oxygen consumption (mo2max). 2. for seals resting in water, the total turnover rates for glucose, lactate, and ffa were 23.2, 26.2, and 7.5 mumols.min-1.kg-1, respectively. direct oxidation of these metabolites accounted for approxi ... | 1991 | 2045543 |
| histopathologic and immunocytochemical studies of distemper in harbor porpoises. | during 1988 thousands of harbor seals (phoca vitulina) died in european seas as a result of morbillivirus infection. six harbor porpoises (phocoena phocoena) found stranded on the coast of northern ireland in late 1988 were submitted to our laboratory for necropsy. pneumonia was the main necropsy finding in three of these animals. microscopic lung lesions characterized by necrosis of bronchial and bronchiolar epithelium and infiltration of alveoli with leukocytes, lymphoid cells, macrophages, an ... | 1991 | 2017822 |
| mycoplasma phocarhinis sp. nov. and mycoplasma phocacerebrale sp. nov., two new species from harbor seals (phoca vitulina l.). | a total of 120 mycoplasma strains were recovered from 97 of 265 diseased seals investigated during the seal epidemic in the north sea and in the baltic sea in 1988. mycoplasmas were isolated from the respiratory tracts (including lungs), hearts, brains, and eyes of the seals. thirty strains were filter cloned and investigated for their morphological, biochemical, and serological characteristics compared with the characteristics of previously described species. the results of an indirect immunofl ... | 1991 | 1995034 |
| lipoproteins in pinnipeds: analysis of a high molecular weight form of apolipoprotein e. | we have examined the apolipoprotein content of the lipoproteins of several marine mammals by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. their apolipoprotein (apo) b-100, apob-48, and apoa-i migrated to virtually the same position as the comparable human apolipoproteins. in cetaceans (bottlenose dolphins and killer whales), the molecular mass of the apoe was identical to that of human apoe (35 kda). in contrast, in the lipoproteins of pinnipeds (harbor seals, sea lions, and walrus ... | 1991 | 1940617 |
| genetic evidence for three species within pseudoterranova decipiens (nematoda, ascaridida, ascaridoidea) in the north atlantic and norwegian and barents seas. | genetic variation of 1017 specimens of codworm, pseudoterranova decipiens, collected from fish and seals at 23 sampling locations in the north atlantic and norwegian and barents seas, was analysed on the basis of 16 enzyme loci. three reproductively isolated species, provisionally designated p. decipiens a, b and c, were detected, showing distinct alleles at the following loci: mdh-1, 6pgdh, np, pgm, est-2 (between species a and b); mdh-3, 6pgdh, np, sod-1, adk, pgm, est-2, mpi (between a and c) ... | 1991 | 1869354 |
| [isolation of the alkaline phosphatase from the intestinal contents of common seal by immobilized monoclonal antibodies]. | it is shown that monoclonal antibodies against the alkaline phosphatase of the greenland seal interact with the alkaline phosphatase of the bowels contents of adult common seal (phoca vitulina larga). the purified antibodies were covalently bound with brcn-activated sepharose 4b and used as an immunosorbent for purification of the alkaline phosphatase of the bowels contents. the specific activity of the purified is equal to 7300 units per 1 mg of protein. | 2015 | 1816691 |
| [amino acid sequence of myoglobin from seals from lake baikal]. | the primary structure of myoglobin of the seal of lake baikal (east siberia) phoca siberica, determined by sequencing the whole protein and peptides obtained by the cyanogen bromide or proteinase cleavage and separated by the microcolumn liquid chromatography, was found to be identical to the primary structures of myoglobins of the harbour seal phoca vitulina largha and the grey seal halehoerus gryphus. it suggests that these species separated from a common ancestor less than seven million years ... | 1991 | 1807253 |
| the helminth fauna from the common seal (phoca vitulina vitulina, linné, 1758) of the wadden sea in lower saxony. part 2: nematodes. | during the seal epidemic in 1988 and the beginning of 1989, 115 common seals found dead on the shores of the wadden sea of lower saxony were investigated for the presence of nematodes. the lungworm otostrongylus circumlitus railliet 1899 was found in 26.1% of the seals, the lungworm parafilaroides gymnurus railliet 1899 in 26.9% and the heartworm dipetalonema spirocauda leidy 1858 in 32.2% of the seals. in the digestive tract, two anisakid species were found, pseudoterranova decipiens mozgovoi 1 ... | 1991 | 1789022 |
| the helminth fauna of the common seal (phoca vitulina vitulina, linné, 1758) from the wadden sea in lower saxony. part 1: trematodes, cestodes and acanthocephala. | between august 1988 and january 1989 110 common seals found dead along the coast of lower saxony were investigated for the occurrence of trematodes, cestodes and acanthocephala. two fluke species, cryptocotyle lingua creplin, 1825 and phagicola septentrionalis van den broek, 1967, two tapeworm species diphyllobothrium cordatum leuckart, 1863 and diphyllobothrium elegans krabbe, 1865, and the acanthocephala species corynosoma strumosum rudolphi, 1802 were found. phagicola septentrionalis and the ... | 1991 | 1789021 |
| purification of alkaline phosphatase from the intestinal content of common seal (phoca vitulina larga) by immunoaffinity chromatography. | 1. a monoclonal antibody app, 1 against harp seal alkaline phosphatase has been prepared. it was found that the antibody was cross-reacted with the intestinal alkaline phosphatase of common seal phoca vitulina larga. 2. purified antibody was linked to sepharose 4b and used for immunoaffinity chromatographic purification of alkaline phosphatase from the intestinal content of common seal. a spec. act. of the purified enzyme was 7300 units per mg of protein. 3. the enzyme in 7.5% polyacrylamide gel ... | 1991 | 1769201 |
| immunological relationships between phocid and canine distemper virus studied with monoclonal antibodies. | the immunological relationships between distemper viruses, isolated from a seal and mink in denmark and from a dog in greenland, were investigated with 39 previously developed monoclonal antibodies (mabs) directed against four major structural proteins of canine distemper virus (cdv). they were also investigated with 16 newly developed mabs directed against the fusion (f) and large glycoprotein (named h in analogy with measles virus) of phocid distemper virus (pdv) isolated from a harbour seal ( ... | 1990 | 1698923 |
| canine distemper virus iscoms induce protection in harbour seals (phoca vitulina) against phocid distemper but still allow subsequent infection with phocid distemper virus-1. | a candidate canine distemper virus (cdv) iscom vaccine has been shown to be effective in protecting harbour seals (phoca vitulina) from phocid distemper in 1988. however, of the 35 harbour seals receiving this vaccine upon admission to a seal rehabilitation and research centre (pieterburen, the netherlands) in 1989, six developed mild inflammatory symptoms of the respiratory tract. phocid distemper virus-1 (pdv-1) could be isolated from three of these animals. this indicates that the vaccine aff ... | 1992 | 1609546 |
| real-time ultrasound for pregnancy diagnosis in the harbour seal (phoca vitulina concolor). | 1992 | 1595162 | |
| the serological response of the common seal (phoca vitulina) and the grey seal (halichoerus grypus) to phocine distemper virus as measured by a canine distemper virus neutralisation test. | the application of a canine distemper virus (cdv) neutralisation test revealed that antibody titres of up to 11,620 were present in the sera of common seals during the epizootic of phocine distemper in british waters. however, during the later stages of the epizootic and afterwards, a surprisingly high proportion of animals were still seronegative. titres of from 90 to 183 were common in diseased animals and were probably indicative of partial immunosuppression. a few animals with proven phocine ... | 1992 | 1594940 |
| disease conditions affecting common seals (phoca vitulina) around the scottish mainland, september-november 1988. | common seal populations around the scottish coast were less severly devastated by phocine distemper than those on the continent. nevertheless, over a 4-month period, 59 common seals were examined postmortem. the macroscopic and histopathological lesions are described. forty-two per cent of these seals were considered to be suffering from phocine distemper. serology on 29 of the 59 seals was undertaken and the results are discussed in relation to the histopathological findings. bordetella bronchi ... | 1992 | 1594936 |
| tissue concentrations of organochlorine compounds in common seals from the coast of northern ireland. | an epizootic of morbillivirus infection killed several hundred common seals (phoca vitulina) along the coast of northern ireland in 1988. many dead and moribund seals were submitted to the department of agriculture for northern ireland, veterinary research laboratories for necropsy. samples of blubber, liver and kidney were collected from these animals (n = 55) for analysis for a wide range of organochlorine pesticides and also total polychlorinated biphenyls (pcbs). the organochlorines found in ... | 1992 | 1594932 |
| organochlorine levels in common seals (phoca vitulina) which were victims and survivors of the 1988 phocine distemper epizootic. | we compared concentrations of organochlorines in the blubber of common seals (phoca vitulina) found dead during the 1988 phocine distemper epizootic with levels in animals which survived it. there were highly significant differences between the live and dead animals, and between sample sites. these were not fully accounted for by seasonal and condition-related changes in blubber thickness. | 1992 | 1594930 |
| plasma thymulin concentrations, the thymus and organochlorine contaminant levels in seals infected with phocine distemper virus. | blood samples collected from live common seals (phoca vitulina) and grey seals (halichoerus grypus) around the coast of scotland and northern ireland during, and immediately after, an epizootic caused by phocid distemper virus (pdv) were analysed for thymulin content. thymulin levels were compared with neutralization titres and concentrations of organochlorine contaminants (ddt and its metabolites, seven chlorinated biphenyl congeners) derived from blood and blubber samples collected from the sa ... | 1992 | 1594929 |
| the complete mitochondrial dna sequence of the harbor seal, phoca vitulina. | the nucleotide sequence of the mitochondrial dna (mtdna) of the harbor seal, phoca vitulina, was determined. the total length of the molecule was 16,826 bp. the organization of the coding regions of the molecule conforms with that of other mammals, but the control region is unusually long. a considerable portion of the control region is made up of short repeats with the motif gtacac particularly frequent. the two rrna genes and the 13 peptide-coding genes of the harbor seal, fin whale, cow, huma ... | 1992 | 1593642 |
| mycoplasma phocidae sp. nov., isolated from harbor seals (phoca vitulina l.). | in 1979 and 1980, more than 400 harbor seals (phoca vitulina) along the new england coast of the united states died of epizootic pneumonia that was attributed to an influenza virus. six mycoplasma isolates that were recovered from the respiratory tracts of affected seals were investigated and were found to be serologically identical and distinct from previously described species. these isolates required serum for growth, did not possess a cell wall, and did not hydrolyze urea. arginine was hydro ... | 1992 | 1581181 |
| investigations on course and outcome of phocine distemper virus infection in harbour seals (phoca vitulina) exposed to polychlorinated biphenyls. virological and serological investigations. | the influence of polychlorinated biphenyls (pcbs) on phocine distemper virus (pdv) infections in harbour seals (phoca vitulina) was studied. six out of ten seals had been conditioned with a defined mixture of pcb-congeners for several weeks. following exposure to the cell culture-propagated pdv isolate 2558/han 88 the complete clinical picture of "1988 seal plague" was provoked in all ten seals inoculated. four out of six pcb-conditioned seals and two out of four seals not loaded with pcbs succu ... | 1992 | 1580105 |
| serologic study of phocine distemper in a population of harbor seals in scotland. | a serologic survey of the prevalence of morbillivirus antibodies was conducted in a population of harbor seals (phoca vitulina) from northeastern scotland, where mortality was comparatively low during the 1988 phocine distemper virus outbreak. none of the 12 seals sampled before the epizootic were seropositive. thirty-five (52%) of 68 seals sampled after the beginning of the epizootic were seropositive, although there were significant age-related differences in both the number of seropositive in ... | 1992 | 1548798 |
| pinniped splenic volumes. | splenic volume was measured by computerized axial tomography in three harbor seals (phoca vitulina) and two california sea lions (zalophus californianus). volumes ranged from 228 to 679 ml, representing 0.8-3.0% of calculated percentage body mass. despite possible variation in the state of splenic contraction during the examination, these values are in the upper range of reported mammalian splenic volumes (as % of body mass). this reinforces the pinniped splenic erythrocyte storage concept. | 1992 | 1539742 |
| a case of cleft palate in a kuril seal (phoca vitulina stejnegeri), from hokkaido, japan. | a male pup kuril seal (phoca vitulina stejnegeri) from hokkaido, japan, was observed with a unilateral and total cleft of the primary palate. complications included a supernumerary tooth, hypoplasia and asymmetry of the face, and deformation of the eyeball and external auditory meatus. an accompanying pneumonia may have resulted from water flowing into the respiratory system due to imperfect closure of the nostril by the cleft. no other abnormalities were found. | 1992 | 1512890 |
| toxic elements and organochlorines in harbor seals (phoca vitulina richardsi), kodiak, alaska, usa. | 1992 | 1504518 | |
| round table on morbilliviruses in marine mammals. | since 1988 morbilliviruses have been increasingly recognized and held responsible for mass mortality amongst harbour seals (phoca vitulina) and other seal species. virus isolations and characterization proved that morbilliviruses from seals in northwest europe were genetically distinct from other known members of this group including canine distemper virus (cdv), rinderpest virus, peste des petits ruminants virus and measles virus. an epidemic in baikal seals in 1987 was apparently caused by a m ... | 1992 | 1481361 |
| herpesvirus infections in seals: a summary of present knowledge. | this review summarises the occurrence of herpesvirus infections in pinnipeds and data from investigations carried out by the authors. these data demonstrate that herpesvirus isolates collected from harbour seals (phoca vitulina linnaeus, 1758) during the 1988 seal epidemic were almost indistinguishable from feline herpesvirus 1 and that antarctic weddell's seals (leptonychotes weddelli lesson, 1826) carry antibodies against seal herpesvirus from the north-western europe seal epidemic. the signif ... | 1992 | 1339068 |
| lenticular lesions in harbour seals (phoca vitulina). | lenticular lesions were found in 21 of 44 mainly younger harbour seals investigated during the epidemic caused by phocine distemper virus (pdv) in 1988/89. malformations and cataracts varied in quality and degree and were histologically characterized by proliferative and/or degenerative lenticular alterations. except for two animals, both eyes were affected symmetrically. for that reason, local exogenous causes are improbable. there was very little evidence for infectious agents isolated from th ... | 1992 | 1291586 |
| dirofilaria immitis infection in a harbor seal. | 1975 | 1176343 | |
| interactions of respiration and the bradycardia of submersion in harbor seals. | six harbor seals with percutaneous tracheostomies were artificially ventilated while immersed. changes in the oxygen content of the inspired gas and in the minute-volume altered the magnitude of the bradycardia observed after the animal had been submerged for 30 s. the average heart rate in five seals changed from 16.7 (s.d. = 4.4) beats per minute during artificial ventilation with n2, to 58.7 (s.d. = 10.4) beats per minute while breathing air, but this cardiac chronotropic effect of oxygen was ... | 1975 | 1175083 |
| metabolism and temperature regulation in young harbor seals phoca vitulina richardi. | metabolism and the ability to regulate core and peripheral temperatures under a variety of ambient conditions were studied in five unrestrained pups (less than 5 wk old) and four 3- to 5-mo-old harbor seals. pups born with nonlanugo (adultlike) hair and little fat were able to swim in 5 degrees c water for several hours without becoming hypothermic. they were also found to tolerate 5 degrees c air temperature with the fur wet and exposed to a 35-knot wind. basal metabolism in pups averaged 0.8 m ... | 1975 | 1167192 |