Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| effects of atrazine and chlorpyrifos on oxidative stress-induced autophagy in the immune organs of common carp (cyprinus carpio l.). | atrazine (atr) and chlorpyrifos (cpf) are the most common agrochemical in the freshwater ecosystems of the world. this study assessed the effects of atr (4.28, 42.8 and 428 μg/l), cpf (1.16, 11.6 and 116 μg/l) and combined atr/cpf (1.13, 11.3 and 113 μg/l) on common carp head kidneys and spleens following 40 d exposure and 40 d recovery treatments. nitric oxide (no) content, activities of anti hydroxyl radical (ahr), anti superoxide anion (asa), peroxidase (pod) and inducible nitric oxide syntha ... | 2015 | 25652291 |
| inheritance of the complete mitochondrial genomes cyprinus capio furong(♀) × cyprinus carpio var.singguonensis(♂). | in this study, 15 sets of primers were used to amplify contiguous, overlapping segments of the complete mitochondrial dna (mtdna) of c. capio furong(♀) × c. carpio var.singguonensis(♂) in order to characterize and compare their mitochondrial genomes. the total length of the mitochondrial genome was 16,581 bp and deposited in the genbank with the accession number kp210473. the organization of the mitochondrial genomes contained 37 genes (13 protein-coding genes, 2 ribosomal rna and 22 transfer rn ... | 2016 | 25648921 |
| the fate of recent duplicated genes following a fourth-round whole genome duplication in a tetraploid fish, common carp (cyprinus carpio). | whole genome duplication (wgd) results in extensive genetic redundancy. in plants and yeast, wgd is followed by rapid gene deletions and intense expression differentiation with slow functional divergence. however, the early evolution of the gene differentiation processes is poorly understood in vertebrates because almost all studied wgds are extremely ancient, and the genomes have returned to a diploid status. common carp had a very recent fourth round of wgd dated to 8 million years ago. it the ... | 2015 | 25645996 |
| genetic connectivity and phenotypic plasticity in the cyprinodont aphanius farsicus from the maharlu basin, south-western iran. | meristic and morphometric characteristics, including otolith data, of the farsi tooth-carp aphanius farsicus, which is endemic to the endorheic maharlu basin in south-western iran, were analysed for a sample of 92 individuals from four spring-streams; dna sequence data (cytochrome b gene) are presented for 29 specimens. some phenotypic variation was detected but the genetic data clearly indicate connectivity between the populations. possible links between phenotypic variation and environmental v ... | 2015 | 25644025 |
| detection of cyanotoxins, β-n-methylamino-l-alanine and microcystins, from a lake surrounded by cases of amyotrophic lateral sclerosis. | a cluster of amyotrophic lateral sclerosis (als) has been previously described to border lake mascoma in enfield, nh, with an incidence of als approximating 25 times expected. we hypothesize a possible association with cyanobacterial blooms that can produce β-n-methylamino-l-alanine (bmaa), a neurotoxic amino acid implicated as a possible cause of als/pdc in guam. muscle, liver, and brain tissue samples from a lake mascoma carp, as well as filtered aerosol samples, were analyzed for microcystins ... | 2015 | 25643180 |
| the resurrection of myxobolus toyamai with a validation of a stunted polar capsule based on morphological evidence. | myxobolus toyamai has long been known as a gill parasite of the common carp cyprinus carpio in europe, asia and north america. recently, a controversy was raised regarding whether this organism was synonymous with thelohanellus toyamai because of ambiguity regarding the validity of the second stunted polar capsule. in the present study, detailed morphological examinations were conducted to reconfirm the presence of the small polar capsule of m. toyamai. the addition of potassium hydroxide or the ... | 2015 | 25640192 |
| effects of cylindrospermopsin on the phagocytic cells of the common carp (cyprinus carpio l.). | cylindrospermopsin is a cyanotoxin with cytotoxic activity. it is released into water during and after cyanobacterial water blooms and thus poses a threat to the health of fish. there is very little information available concerning the effects of the toxin on fish immune cells. in this study, we assessed the potential impact of cylindrospermopsin on the basic functions of phagocytic cells from common carp (cyprinus carpio l.), including phagocytosis, reactive oxygen and nitrogen species producti ... | 2015 | 25639895 |
| anti-inflammatory and hepatoprotective effects of ganoderma lucidum polysaccharides on carbon tetrachloride-induced hepatocyte damage in common carp (cyprinus carpio l.). | the aim of this study was to investigate the anti-inflammatory and hepatoprotective effects of ganoderma lucidum polysaccharides (glps) on carbon tetrachloride (ccl4)-induced hepatocyte damage in common carp (cyprinus carpio l.). glps (0.1, 0.3, 0.6mg/ml) were added to the primary hepatocytes before (pre-treatment), after (post-treatment) and both before and after (pre- and post-treatment) the incubation of the hepatocytes with ccl4 at the concentration of 8mm in the culture medium. the supernat ... | 2015 | 25639226 |
| small interfering rna treatment can inhibit cyprinid herpesvirus 3 associated cell death in vitro. | a cyprinid herpesvirus 3 infection of carp induces a disease which causes substantial losses in carp culture. here we present the use of a possible strategy for the management of the virus infection rna interference based on small interfering rnas. as a result of in vitro studies, we found that a mixture of short interfering rnas specific for viral dna enzyme synthesis and capsid proteins of the cyhv-3 can be a potential inhibitor of virus replication in fibroblastic cells. this gives the basis ... | 2014 | 25638991 |
| resistance of common carp (cyprinus carpio l.) to oxidative stress after chloramine-t treatment is increased by microalgae carotenoid-rich diet. | in fish aquaculture, disinfectants are used against bacterial and protozoal infections. these compounds cause oxidative stress that may stimulate the generation of reactive oxygen species, and subsequently the alteration in antioxidant systems of exposed organisms. antioxidants like carotenoids present in microalgae increase carp resistance to oxidative stress after chemical treatment. | 2014 | 25638369 |
| susceptibility, metacercarial burden, and mortality of juvenile silver barb, common carp, mrigal, and tilapia following exposure to haplorchis taichui. | fish-borne zoonotic trematodes (fzt) including heterophyids and opisthorchiids are prevalent in native and aquaculture fish in southeast asia. fzt are reported highly prevalent in juvenile aquaculture fish that belonged to the family heterophyidae, particularly haplorchis taichui. aquaculture fish are reported to have varying levels of natural infection with h. taichui, but data for their susceptibility as well as resistance to infection are not available. the aim of this study was to determine ... | 2015 | 25636245 |
| examining pyrethroids, carbamates and neonicotenoids in fish, water and sediments from the indus river for potential health risks. | this 3 × 3 factorial study assessed pyrethroids, carbamates and neonicotenoids groups of pesticides in replicated samples of three fish species from low (s1, reference), medium (s2) and heavy (s3) polluted sites receiving agricultural run-offs around the indus river. water and sediment samples from the same sites were also analysed for these pesticides by using high-performance liquid chromatography. out of nine investigated pesticides, only three pesticides (deltamethrin, carbofuran and cyperme ... | 2015 | 25632902 |
| alfaxalone as an intramuscular injectable anesthetic in koi carp (cyprinus carpio). | fish are commonly anesthetized with ms-222 (tricaine methanesulfonate), a sodium-channel-blocker used as an immersion anesthetic, but its mechanism of action as a general anesthetic is uncertain. alfaxalone is a neurosteroid that acts at the gaba(a) receptors. alfaxalone has been evaluated and was deemed successful as an immersion agent in koi carp. alfaxalone is an effective intramuscular anesthetic in multiple species. a reliable intramuscular anesthetic in fish would be useful in multiple set ... | 2014 | 25632673 |
| detection of cyprinid herpesvirus 2 in peripheral blood cells of silver crucian carp, carassius auratus gibelio (bloch), suggests its potential in viral diagnosis. | epidemics caused by cyprinid herpesvirus 2 (cyhv-2) in domestic cyprinid species have been reported in both european and asian countries. although the mechanisms remain unknown, acute cyhv-2 infections generally result in high mortality, and the surviving carps become chronic carriers displaying no external clinical signs. in this study, in situ hybridization analysis showed that cyhv-2 tended to infect peripheral blood cells during either acute or chronic infections in silver crucian carp, cara ... | 2016 | 25630360 |
| complete mitochondrial genome sequence of labeo fimbriatus (bloch, 1975). | the complete mitochondrial genome of labeo fimbriatus, the fringe-lipped carp, was determined for the first time. the genome was 16,614 bp in length and consisted of 13 protein-coding genes, 22 trna genes, 2 rrna genes and one control region. organization of genes and their order are in accordance with other vertebrates. the overall base composition on the plus strand was a: 32.35%, g: 15.46%, c: 27.54%, t: 24.647%, and the a + t content 57%. the control region contains a microsatellite, (ta)12, ... | 2016 | 25629503 |
| temporal dynamics of a local fish community are strongly affected by immigration from the surrounding metacommunity. | a 5-year time series of annual censuses was collected from a large floodplain lake to determine how dynamics of the local fish community were affected by changes in hydrological connectivity with the surrounding metacommunity. the lake was disconnected from the metacommunity for 1 year prior to our study and remained disconnected until 3 months before our third annual census, when a flood reconnected the lake to the metacommunity. we determined how changes in connectivity affected temporal dynam ... | 2015 | 25628877 |
| effect of heat treatment on the n-3/n-6 ratio and content of polyunsaturated fatty acids in fish tissues. | the aim of this study was to compare the effect of different heat treatments (pan-frying, oven-baking, and grilling) on the contents of polyunsaturated fatty acids (pufas) in fish tissue. four fish species were examined: pike, carp, cod, and herring. high performance liquid chromatography, coupled with electrospray ionization and mass spectrometric detection (hplc/esi/ms), was employed for determination of intact lipid molecules containing n-3 and n-6 pufas. although mostly non-polar lipids (tri ... | 2015 | 25624225 |
| preparation of nanoemulsions containing unsaturated fatty acid concentrate-chitosan capsules. | fish oil is rich in unsaturated fatty acids (ω-3), which are highly susceptible to oxidative degradation. the use of encapsulation process to retard the fatty acid oxidation is an interesting alternative. in this work, nanoemulsions containing capsules of unsaturated fatty acids concentrate (ufac) using chitosan as wall material were prepared and characterized. | 2015 | 25617613 |
| dbc1/ccar2 and ccar1 are largely disordered proteins that have evolved from one common ancestor. | deleted in breast cancer 1 (dbc1, ccar2, kiaa1967) is a large, predominantly nuclear, multidomain protein that modulates gene expression by inhibiting several epigenetic modifiers, including the deacetylases sirt1 and hdac3, and the methyltransferase suv39h1. dbc1 shares many highly conserved protein domains with its paralog cell cycle and apoptosis regulator 1 (ccar1, carp-1). in this study, we examined the full-length sequential and structural properties of dbc1 and ccar1 from multiple species ... | 2014 | 25610865 |
| differential effects of alloherpesvirus cyhv-3 and rhabdovirus svcv on apoptosis in fish cells. | whilst herpesviridae, which infect higher vertebrates, actively influence host immune responses to ensure viral replication, it is mostly unknown if alloherpesviridae, which infect lower vertebrates, possess similar abilities. an important antiviral response is clearance of infected cells via apoptosis, which in mammals influences the outcome of infection. here, we utilise common carp infected with cyhv-3 to determine the effect on the expression of genes encoding apoptosis-related proteins (p53 ... | 2015 | 25596969 |
| characterization of two thymosins as immune-related genes in common carp (cyprinus carpio l.). | prothymosin alpha (protα) and thymosin beta (tβ) belong to thymosin family, which consists of a series of highly conserved peptides involved in stimulating immune responses. protα b and tβ are still poorly studied in teleost. here, the full-length cdnas of protα b and tβ-like (tβ-l) were cloned and identified in common carp (cyprinus carpio l.). the expressions of carp protα b and tβ-l exhibited rise-fall pattern and then trended to be stable during early development. after spring viraemia of ca ... | 2015 | 25596145 |
| anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis. | anti-carbamylated protein (anti-carp) antibodies could further elucidate early rheumatoid arthritis (ra) pathogenesis and predict clinical disease. we compared the diagnostic accuracy of anti-carp antibodies for future ra to other ra-related antibodies in military personnel. | 2015 | 25593232 |
| chemical composition and immunomodulatory effects of enzymatic protein hydrolysates from common carp (cyprinus carpio) egg. | the aim of this study was to prepare protein hydrolysates from underutilized common carp (cyprinus carpio) egg and to investigate their immunomodulatory effects in vivo. | 2015 | 25592018 |
| oxidative stress and histopathological alterations in liver of cyprinus carpio l. induced by intraperitoneal injection of microcystin-lr. | microcystins (mcs) are a group of cyclic heptapeptide hepatotoxic peptides produced by cyanobacteria. microcystins-lr (mc-lr) can inhibit the activities of protein phosphatase type 1 and type 2a (pp1 and pp2a) and induce excessive production of reactive oxygen species (ros). however, the detailed toxicological mechanism involving oxidative stress in carp (cyprinus carpio l.) remains largely unclear. in our present study, the effects of sublethal intraperitoneal doses of mc-lr on the oxidative st ... | 2015 | 25586193 |
| profiling of skeletal muscle ankrd2 protein in human cardiac tissue and neonatal rat cardiomyocytes. | muscle-specific mechanosensors ankrd2/arpp (ankyrin repeat protein 2) and ankrd1/carp (cardiac ankyrin repeat protein) have an important role in transcriptional regulation, myofibrillar assembly, cardiogenesis and myogenesis. in skeletal muscle myofibrils, ankrd2 has a structural role as a component of a titin associated stretch-sensing complex, while in the nucleus it exerts regulatory function as transcriptional co-factor. it is also involved in myogenic differentiation and coordination of myo ... | 2015 | 25585647 |
| proteomic changes in the brain of the western painted turtle (chrysemys picta bellii) during exposure to anoxia. | during anoxia, overall protein synthesis is almost undetectable in the brain of the western painted turtle. the aim of this investigation was to address the question of whether there are alterations to specific proteins by comparing the normoxic and anoxic brain proteomes. reductions in creatine kinase, hexokinase, glyceraldehyde-3-phosphate dehydrogenase, and pyruvate kinase reflected the reduced production of adenosine triphosphate (atp) during anoxia while the reduction in transitional endopl ... | 2015 | 25583675 |
| novel associations between contaminant body burdens and biomarkers of reproductive condition in male common carp along multiple gradients of contaminant exposure in lake mead national recreation area, usa. | adult male common carp were sampled in 2007/08 over a full reproductive cycle at lake mead national recreation area. sites sampled included a stream dominated by treated wastewater effluent, a lake basin receiving the streamflow, an upstream lake basin (reference), and a site below hoover dam. individual body burdens for 252 contaminants were measured, and biological variables assessed included physiological [plasma vitellogenin (vtg), estradiol-17β (e2), 11-ketotestosterone (11kt)] and organ [g ... | 2015 | 25583583 |
| chronic exposure to pollutants in madín reservoir (mexico) alters oxidative stress status and flesh quality in the common carp cyprinus carpio. | madín reservoir (mr) is located on the río tlalnepantla in mexico. previous studies seeking to identify pollutants at this site evidence that mr water contains a considerable metal load as well as nonsteroidal anti-inflammatory drugs (nsaids) at concentrations above those determined suitable for aquatic life. this study aimed to evaluate whether chronic exposure to pollutants in mr alters oxidative stress status and flesh quality in muscle of the common carp cyprinus carpio. the following biomar ... | 2015 | 25583264 |
| reversible brain swelling in crucian carp (carassius carassius) and goldfish (carassius auratus) in response to high external ammonia and anoxia. | increased internal ammonia (hyperammonemia) and ischemic/anoxic insults are known to result in a cascade of deleterious events that can culminate in potentially fatal brain swelling in mammals. it is less clear, however, if the brains of fishes respond to ammonia in a similar manner. the present study demonstrated that the crucian carp (carassius carassius) was not only able to endure high environmental ammonia exposure (hea; 2 to 22 mmol l(-1)) but that they experienced 30% increases in brain w ... | 2015 | 25582543 |
| responses of the hepatic glutathione antioxidant defense system and related gene expression in juvenile common carp after chronic treatment with tributyltin. | recently, residual organotin compounds have generally been recognised as relevant sources of aquatic environmental pollutants. however, the effects of these contaminants on the glutathione (gsh)-antioxidant system of fishes have not been adequately studied. in the current study, the chronic effects of tributyltin (tbt) found within antifouling paints for ships, on the gsh antioxidant system and related gene expression in the liver of juvenile common carp (cyprinus carpio) were investigated. fish ... | 2015 | 25582114 |
| trypsin from the digestive system of carp cirrhinus mrigala: purification, characterization and its potential application. | trypsin was purified 35.64-fold with 4.97% recovery from the viscera of carp cirrhinus mrigala (mrigal) by ammonium sulfate precipitation, ion exchange and affinity chromatography. the purified enzyme was active at a wide range of ph (7.0-9.2) and temperature (10-50°c). the purified enzyme exhibited high thermal stability up to 50°c for 1h. the enzyme activity was stabilized by ca(+2) (2mm) up to 7h at 40°c. the km and kcat values of purified enzyme were 0.0672 mm and 92.09/s/mm, respectively. s ... | 2015 | 25577096 |
| chronic effects of tributyltin on multiple biomarkers responses in juvenile common carp, cyprinus carpio. | in this study, the chronic toxic effects of tributyltin (tbt), an antifouling paints commonly present in surface and ground water, on morphological indices, reactive oxygen species (ros) generation, and atpase activity and heat shock protein (hsp) 70 protein in tissues (liver, gill, and white muscle) of common carp were investigated. fish were exposed at sublethal concentrations of tbt (75 ng/l, 0.75 μg/l, and 7.5 μg/l) for 60 days. when compared with the control, there was significant lower con ... | 2016 | 25573135 |
| protective effects of lycium barbarum polysaccharides against carbon tetrachloride-induced hepatotoxicity in precision-cut liver slices in vitro and in vivo in common carp (cyprinus carpio l.). | the protective effects of lycium barbarum polysaccharides (lbps) against carbon tetrachloride-induced hepatotoxicity in common carp were investigated in vitro and in vivo. precision-cut liver slices (pclss) were employed as an in vitro model system. lbps (0.1, 0.3 and 0.6 mg/ml) was added to pclss culture system before (pre-treatment), after (post-treatment) and both before and after (pre- and post-treatment) the exposure of pclss to 12 mm ccl4. the supernatants and pclss were collected for bioc ... | 2015 | 25572856 |
| [the cloning of hif-2α gene and hydroxylation assay of hif-2α odd domain in naked carp from qinghai lake]. | 2014 | 25571630 | |
| assessment of pesticide residues and gene expression in common carp exposed to atrazine and chlorpyrifos: health risk assessments. | this study assessed the impacts of atrazine (atr), chlorpyrifos (cpf) and combined atr/cpf exposure on the kidney of common carp (cyprinus carpio l.). the carp were sampled after a 40-d exposure to cpf and atr, individually or in combination, followed by a 40-d recovery to measure the expression levels of heat shock proteins genes (hsp60, hsp70 and hsp90) and pesticide residues in the kidney tissue. the results revealed that the mrna and protein levels of hsp60, hsp70 and hsp90 were induced in t ... | 2015 | 25568939 |
| [prevalence of sensitization to allergens in 1 139 patients with allergic rhinitis in zhengzhou area]. | to investigate the main allergens in patients with allergic rhinitis in zhengzhou district. | 2014 | 25567444 |
| the in vitro immune modulatory effect of bisphenol a on fish macrophages via estrogen receptor α and nuclear factor-κb signaling. | bisphenol a (bpa) is a well-known environmental endocrine-disrupting chemical. employing primary macrophages from head kidney of red common carp (cyprinus carpio), the present study aimed to evaluate the immune modulatory effect of bpa and to explore its potential action mechanism associated with estrogen receptor (er) and nuclear factor-κb (nf-κb) pathways. a dynamic response process was observed in macrophages upon various concentrations of bpa exposure, which significantly enhanced the antiba ... | 2015 | 25565130 |
| fullerene-associated phenanthrene contributes to bioaccumulation but is not toxic to fish. | the present study investigated the effects of aqueous fullerene suspensions (nc60 ) on the bioavailability and toxicity of phenanthrene (phe) to junior carp (cyprinus carpio). bioaccumulation factors (bafs) were calculated based on total as well as free concentrations of phe. equal baf values were obtained with and without nc60 based on the total concentrations, whereas greater bafs were found in the presence of nc60 when free phe concentrations were applied. the results demonstrated that nc60 c ... | 2015 | 25564991 |
| copper exposure induces toxicity to the antioxidant system via the destruction of nrf2/are signaling and caspase-3-regulated dna damage in fish muscle: amelioration by myo-inositol. | the muscle is the main portion of fish that is consumed by humans. copper (cu) can induce oxidative damage in fish muscle. however, the effects of cu exposure on the muscle antioxidant system and molecular patterns and preventive measures against these effects remain unclear. in this study, ros production, enzymatic and mrna levels of antioxidant enzymes and nf-e2-related factor 2 (nrf2) signaling-related molecules, antioxidant response element (are) binding ability, dna fragmentation and caspas ... | 2015 | 25562835 |
| the effect of reactive oxygen species on motility parameters, dna integrity, tyrosine phosphorylation and phosphatase activity of common carp (cyprinus carpio l.) spermatozoa. | the effect of reactive oxygen species production on the motility parameters, dna integrity, acid phosphatase activity, and protein tyrosine phosphorylation in spermatozoa of the common carp (cyprinus carpio) was investigated. spermatozoa were exposed to different concentrations of xanthine and xanthine oxidase (x-xo) either in the presence or absence of antioxidants for 15 and 60 min. a dose- and time-dependent reduction in spermatozoa motility and velocity was observed. comet assays showed a dr ... | 2015 | 25556750 |
| prevalence and characteristics of cyprinid herpesvirus 3 (cyhv-3) infection in common carp (cyprinus carpio l.) inhabiting three rivers in kochi prefecture, japan. | cyprinid herpesvirus 3 (cyhv-3) causes lethal disease in common and koi carp. mortality by cyhv-3 disease has not been reported since 2011 in kochi prefecture, japan. here, we detected and quantified cyhv-3 in common carp inhabiting three rivers in the prefecture to examine if the carp are carriers of cyhv-3 as a source of infection. cyhv-3 dna was detected in 16.7% (12/72) of brain samples in kagami river, 3.9% (3/76) of brain and 3.9% (3/76) of gill samples in monobe river, and 5.1% (4/79) of ... | 2015 | 25554244 |
| genome wide identification, phylogeny and expression of zinc transporter genes in common carp. | zinc is an essential trace element in organisms, which serves as a cofactor for hundreds of enzymes that are involved in many pivotal biological processes including growth, development, reproduction and immunity. therefore, the homeostasis of zinc in the cell is fundamental. the zinc transporter gene family is a large gene family that encodes proteins which regulate the movement of zinc across cellular and intracellular membranes. however, studies on teleost zinc transporters are mainly limited ... | 2014 | 25551462 |
| effects of curcumin on antioxidative activities and cytokine production in jian carp (cyprinus carpio var. jian) with ccl4-induced liver damage. | we investigated the protective effects of curcumin on liver-damaged cyprinus carpio var. jian (jian carp). the carp were fed 0.1%, 0.5%, or 1.0% curcumin for 60 days, then injected intraperitoneally with 30% carbon tetrachloride solution. liver and blood samples were collected to measure the liver index, serum- and liver-associated enzymes, liver histology, nuclear factor-κb (nf-κb)/c-rel, interleukin-1β (il-1β), tumor necrosis factor-α (tnf-α), and il-12 mrna expression, and the level of nf-κb/ ... | 2015 | 25549934 |
| β-alanine does not act through branched-chain amino acid catabolism in carp, a species with low muscular carnosine storage. | this study was executed to investigate the effect of dietary β-alanine (ba) on amino acid (aa) metabolism and voluntary feed intake in carp (cyprinus carpio) at mildly elevated temperature to exert aa catabolism. twenty-four fish in 12 aquaria were randomly assigned to either a control diet or the same diet with 500 mg ba/kg. a 14-day period at an ideal temperature (23 °c) was followed by 15 days at chronic mildly elevated temperature (27 °c). after the 15 days, all fish were euthanised for musc ... | 2015 | 25549626 |
| haematological effects of 2-phenoxyethanol and etomidate in carp (cyprinus carpio l.). | to evaluate the effects of handling alone versus handling under anaesthesia with 2-phenoxyethanol or etomidate on haematological parameters in carp. | 2015 | 25545607 |
| disturbance in z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy. | familial restrictive cardiomyopathy (frcm) has a poor prognosis due to diastolic dysfunction and restrictive physiology (rp). myocardial stiffness, with or without fibrosis, underlie rp, but the mechanism(s) of restrictive remodeling is unclear. myopalladin (mypn) is a messenger molecule that links structural and gene regulatory molecules via translocation from the z-disk and i-bands to the nucleus in cardiomyocytes. expression of n-terminal mypn peptide results in severe disruption of the sarco ... | 2014 | 25541130 |
| molecular characterization and expression of three preprosomatostatin genes and their association with growth in common carp (cyprinus carpio). | somatostatins (sss) are a structurally diverse family of peptides that play important roles in the regulation of growth, development and metabolism in vertebrates. in this study, three preprosomatostatin genes (psss) in the common carp, cyprinus carpio (cc) were identified and characterized. based on cloned sequences and genome blast, six isoforms of the pss gene in c. carpio (ccpss) were identified and included ccpss1a and ccpss1b, ccpss2a and ccpss2b, and finally, ccpss3a and ccpss3b. the open ... | 2015 | 25536408 |
| zebrafish irf1 regulates ifn antiviral response through binding to ifnϕ1 and ifnϕ3 promoters downstream of myd88 signaling. | in mammals, type i ifns (mainly ifn-α/β) are primarily regulated by transcription factors of the ifn regulatory factor (irf) family. fish ifns do not show a one-to-one orthologous relationship with mammalian type i ifn homologues. using a bacterial one-hybrid reporter screening system and an overexpression approach to explore the molecular mechanism underlying fish ifn induction, we identified zebrafish danio rerio irf (drirf)1 as a positive regulator of the fish ifn antiviral response. among 12 ... | 2015 | 25535281 |
| rdh13l, an enzyme responsible for the aldehyde-alcohol redox coupling reaction (al-ol coupling reaction) to supply 11-cis retinal in the carp cone retinoid cycle. | cone photoreceptors require effective pigment regeneration mechanisms to maintain their sensitivity in the light. our previous studies in carp cones suggested the presence of an unconventional and very effective mechanism to produce 11-cis retinal, the necessary component in pigment regeneration. in this reaction (aldehyde-alcohol redox coupling reaction, al-ol coupling reaction), formation of 11-cis retinal, i.e. oxidation of 11-cis retinol is coupled to reduction of an aldehyde at a 1:1 molar ... | 2015 | 25533474 |
| the compression anastomotic ring-locking procedure: a novel technique for creating a sutureless colonic anastomosis. | compression anastomoses might represent an improvement over traditional hand-sewn or stapled techniques. herein, we describe a novel concept of sutureless colonic anastomosis named compression anastomotic ring-locking procedure (carp). | 2015 | 25531546 |
| assessment of oxidative damage to dna, transcriptional expression of key genes, lipid peroxidation and histopathological changes in carp cyprinus carpio l. following exposure to chronic hypoxic and subsequent recovery in normoxic conditions. | in fish, a complex set of mechanisms deal with environmental stresses including hypoxia. in order to probe the hypothesis that hypoxia-induced stress could be manifested in varieties of pathways, a model species, mirror carp (cyprinus carpio), were chronically exposed to hypoxic condition (dissolved oxygen level: 1.80 ± 0.6 mg/l) for 21 days and subsequently allowed to recover under normoxic condition (dissolved oxygen level: 8.2 ± 0.5 mg/l) for 7 days. at the end of these exposure periods, an i ... | 2015 | 25527733 |
| higher antiviral response of rig-i through enhancing rig-i/mavs-mediated signaling by its long insertion variant in zebrafish. | as an intracellular pattern recognition receptor (prr), the retinoic acid-inducible gene-i (rig-i) is responsible for the recognition of cytosolic viral nucleic acids and the production of type i interferons (ifns). in the present study, an insertion variant of rig-i with 38 amino acids inserted in the n-terminal card2 domain, as well as the typical type, named as rig-ia and rig-ib respectively were identified in zebrafish. rig-ia and rig-ib were all up-regulated following the infection of a neg ... | 2015 | 25524497 |
| fatty acid composition of freshwater wild fish in subalpine lakes: a comparative study. | in this study, the proximate and fatty acid compositions of the muscle tissue of 186 samples of fish belonging to fifteen species of freshwater fish harvested in subalpine lakes (bleak, shad, crucian carp, whitefish, common carp, pike, black bullhead, burbot, perch, italian roach, roach, rudd, wels catfish, chub and tench) were investigated. most of the fish demonstrated a lipid content in the fillet lower than 2.0 g 100 g(-1) wet weight (range 0.6-9.7). a strong relationship between feeding beh ... | 2015 | 25519933 |
| [the effect of weak low-frequency magnetic fields on the intracellular calcium-dependent proteinases of fish]. | the in vivo and in vitro effects of weak, low-frequency magnetic fields with resonance parameters for calcium ions upon intracellular calcium-dependent proteinases (calpains) in the crucian carp (carassius carassius (l.) and roach (rutilus rutilus (l.) were studied. it has been revealed that the impact of a weak low-frequency magnetic field leads to considerable decrease in the activity of calpains in the fish skeletal muscles and brain. | 2016 | 25518552 |
| short and long-term exposure to diclofenac alter oxidative stress status in common carp cyprinus carpio. | diclofenac (dcf) has been detected in significant amounts in municipal treated wastewater effluent. diverse studies report that trace concentrations of dcf may induce toxic effects on different aquatic organisms as well as developmental, reproductive and renal damage. this study aimed to determine whether short and long-term exposure to dcf alter the oxidative stress (os) status in blood, muscle, gills, brain and liver of common carp cyprinus carpio. the median lethal concentration of dcf at 96 ... | 2015 | 25512029 |
| overexpression of ankyrin repeat domain 1 enhances cardiomyocyte apoptosis by promoting p53 activation and mitochondrial dysfunction in rodents. | the ankrd1 (ankyrin repeat domain 1) gene is known to be up-regulated in heart failure and acts as a co-activator of p53, modulating its transcriptional activity, but it remains inconclusive whether this gene promotes or inhibits cell apoptosis. in the present study, we attempted to investigate the role of ankrd1 on angii (angiotensin ii)- or pressure-overload-induced cardiomyocyte apoptosis. in the failing hearts of mice with pressure overload, the protein expression of ankrd1-encoded carp (car ... | 2015 | 25511237 |
| [adaptive increase of serotonergic system activity in tissues of half-migratory and migratory fish at increased water salinity]. | the article deals with studies of the serotoninergic system activity in different tissues of half-migratory fish--the caspian roach (rutilus rutilus caspicus) and carpbream (abramis brama orientalis)--and migratory fish--shemaya (chalcalburnus chalcoides) caught in fresh and brackish waters, as well as in the common carp (cyprinus carpio l.) tissues under effect of brackish water in model experiments. using indirect solid-phase elisa-test, the serotoninergic system activity was evaluated by meas ... | 2014 | 25509051 |
| [effect of serotonin-modulated anticonsolidation protein on formation of long-term memory in carps cyprinus carpio in the model of active avoidance learning]. | effect of serotonin-modulated anticonsolidation protein (smap) that has property of disturbing formation of memory trace in mammals and of learning and memory in teleost fish was studied in the model of active avoidance learning. the experiment was performed in three stages: (1) fry of carps cyprinus carpio l. was injected intracerebrovenricularly with the smap protein at a dose of 0.3 μg/g; control individuals were administered with equal amount of the buffered saline for poikilothermic animals ... | 2014 | 25508936 |
| [effect of rate of water temperature increase on sensitivity of fish digestive glycosidases to action of copper and zinc]. | an increase in sensitivity of glycosidases of intestinal mucosa has been established in fry of goldfish carassius auratus, carp cyprinus carpio, roach rutilus rutilus, and common perch perca fluviatilis to action in vitro of heavy metal ions (copper and zinc at concentrations of 0.1-25 mg/l) at heating of water at the summer period. the inhibitory effect of copper and zinc ions as a rule was higher at the heating rate of 50 degrees c/h than at the rate of 4 degrees c/h. glycosidases of the perch ... | 2014 | 25508933 |
| distribution and bioaccumulation of lead in the coastal watersheds of the northern bohai and yellow seas in china. | in this study, the concentration of lead ([pb]) in the surface water, sediments, soils and muscles of carp and crab in the upstream and downstream coastal watersheds along the northern bohai and yellow seas (nbys) in china was investigated and the risks of pb were evaluated. the mean [pb] in the downstream water (2.62 μg/l) and sediments [24.5 mg/kg, dry mass (dm)] was greater than the chinese seawater quality standard for class i (1 μg/l) and the regional background soil concentration (11.5 mg ... | 2015 | 25503512 |
| analysing codon usage bias of cyprinid herpesvirus 3 and adaptation of this virus to the hosts. | the codon usage patterns of open reading frames (orfs) in cyprinid herpesvirus 3 (cyhv-3) have been investigated in this study. the high correlation between gc12 % and gc3 % suggests that mutational pressure rather than natural selection is the main factor that determines the codon usage and base component in the cyhv-3, while mutational pressure effect results from the high correlation between gc3 % and the first principal axis of principle component analysis (axis 1) on the relative synonymous ... | 2015 | 25491502 |
| [adaptive increase of serotonergic system activity in tissues of half-migratory and migratory fish at increased water salinity]. | the article deals with studies of the serotoninergic system activity in different tissues of half-migratory fish--the caspian roach (rutilus rutilus caspicus) and carpbream (abramis brama orientalis)--and migratory fish--shemaya (chalcalburnus chalcoides) caught in fresh and brackish waters, as well as in the common carp (cyprinus carpio l.) tissues under effect of brackish water in model experiments. using indirect solid-phase elisa-test, the serotoninergic system activity was evaluated by meas ... | 2014 | 25490850 |
| genomic cloning and sequence analysis of interleukin-10 from labeo rohita. | interleukin-10 (il-10) is a pleiotropic cytokine and plays an important role in inflammation, immunoregulation and the pathogenesis of various diseases. therefore, it is our interest to isolate, clone, sequence and characterize il-10 gene from the fish labeo rohita (lr). the gene was amplified using genomic dna isolated from head kidney with primers designed on conserved sequence homologues of fishes belonging to cyprinidae family. the glril-10 is 1467 nucleotides long with five exons and four i ... | 2014 | 25489171 |
| a novel posavirus-related single-stranded rna virus from fish (cyprinus carpio). | the complete genome sequence of a novel +ssrna virus, provisionally named fisavirus 1 (strain hal1/fisa-ssrnav, km434233), identified from a freshwater carp (cyprinus carpio), was determined using viral metagenomics and rt-pcr. the 8712-nt-long genome of hal1/fisa-ssrnav shares the same genome organization (i.e., a potential single orf and n-terminal hel-pro-pol replication domains followed by the structural proteins) and distant phylogenetic relationship to the currently unclassified posaviruse ... | 2015 | 25488292 |
| gill infection model for columnaris disease in common carp and rainbow trout. | challenge models generating gill lesions typical for columnaris disease were developed for the fry of both common carp cyprinus carpio and rainbow trout oncorhynchus mykiss by means of an immersion challenge and flavobacterium columnare field isolates were characterized regarding virulence. carp inoculated with highly virulent isolates revealed diffuse, whitish discoloration of the gills affecting all arches, while in trout mostly unilateral focal lesions, which were restricted to the first two ... | 2015 | 25488182 |
| localization of α-synuclein in teleost central nervous system: immunohistochemical and western blot evidence by 3d5 monoclonal antibody in the common carp, cyprinus carpio. | alpha synuclein (α-syn) is a 140 amino acid vertebrate-specific protein, highly expressed in the human nervous system and abnormally accumulated in parkinson's disease and other neurodegenerative disorders, known as synucleinopathies. the common occurrence of α-syn aggregates suggested a role for α-syn in these disorders, although its biological activity remains poorly understood. given the high degree of sequence similarity between vertebrate α-syns, we investigated this proteins in the central ... | 2015 | 25488013 |
| [effect of serotonin-modulated anticonsolidation protein on formation of long-term memory in carps cyprinus carpio in the model of active avoidance learning]. | effect of serotonin-modulated anticonsolidation protein (smap) that has property of disturbing formation of memory trace in mammals and of learning and memory in teleost fish was studied in the model of active avoidance learning. the experiment was performed in three stages: (1) fry of carps cyprinus carpio l. was injected intracerebrovenricularly with the smap protein at a dose of 0.3 μg/g; control individuals were administered with equal amount of the buffered saline for poikilothermic animals ... | 2014 | 25486805 |
| [effect of rate of water temperature increase on sensitivity of fish digestive glycosidases to action of copper and zinc]. | an increase in sensitivity of glycosidases of intestinal mucosa has been established in fry of goldfish carassius auratus, carp cyprinus carpio, roach rutilus rutilus, and common perch perca fluviatilis to action in vitro of heavy metal ions (copper and zinc at concentrations of 0.1-25 mg/l) at heating of water at the summer period. the inhibitory effect of copper and zinc ions as a rule was higher at the heating rate of 50 degrees c/h than at the rate of 4 degrees c/h. glycosidases of the perch ... | 2014 | 25486802 |
| novel single nucleotide polymorphisms of the insulin-like growth factor-i gene and their associations with growth traits in common carp (cyprinus carpio l.). | insulin-like growth factor-i (igf-i) plays an important role in the growth and development of vertebrates. to study polymorphisms of igf-i, we screened a total of 4555 bp of genomic sequences in four exons and partial introns for the discovery of single nucleotide polymorphism (snp) in common carp (cyprinus carpio). three snps (g.3759t>g, g.7627t>a and g.7722t>c) in intron 2 and a nonsynonymous snp (g.7892c>t) in exon 3 were identified in a pilot population including random parents and their pro ... | 2014 | 25486058 |
| g-protein coupled estrogen receptor (gper) inhibits final oocyte maturation in common carp, cyprinus carpio. | gpr-30, now named as gper (g protein-coupled estrogen receptor) was first identified as an orphan receptor and subsequently shown to be required for estrogen-mediated signaling in certain cancer cells. later studies demonstrated that gper has the characteristics of a high affinity estrogen membrane receptor on atlantic croaker and zebra fish oocytes and mediates estrogen inhibition of oocyte maturation in these two distantly related teleost. to determine the broad application of these findings t ... | 2015 | 25485460 |
| atrazine and chlorpyrifos exposure induces liver autophagic response in common carp. | under normal conditions, autophagy occurs at basal levels but can be induced rapidly in response to stress conditions and extracellular signals. increasing experimental evidence indicates that the expression of autophagy-related genes play very important roles in toxicology. atrazine (atr) and chlorpyrifos (cpf) are the most common agrochemical in the freshwater ecosystems of the world. this study assessed the effects of atr, cpf and combined atr/cpf exposure on the liver of common carp. carp we ... | 2015 | 25483372 |
| caffeine-induced ca(2+) oscillations in type i horizontal cell of carp retina: a mathematical model. | oscillations in intracellular free ca(2+) concentration ([ca(2+)]i) have been observed in a variety of cell types. in the present study, we constructed a mathematical model to simulate the caffeine-induced [ca(2+)]i oscillations based on experimental data obtained from isolated type i horizontal cell of carp retina. the results of model analysis confirm the notion that the caffeine-induced [ca(2+)]i oscillations involve a number of cytoplasmic and endoplasmic ca(2+) processes that interact with ... | 2014 | 25483284 |
| temperature effects on the fracture resistance of scales from cyprinus carpio. | in this investigation the fracture resistance of scales from cyprinus carpio was evaluated as a function of environmental temperature. tear specimens were prepared from scales obtained from three characteristic regions (i.e. head, mid-length and tail) of multiple fish. the fracture resistance was characterized in mode iii loading and over temperatures ranging from -150°c to 21°c. results showed that there was a significant reduction in tear resistance with decreasing temperature and the lowest r ... | 2015 | 25481741 |
| hepatoprotective effects of a chinese herbal formulation, yingchen decoction, on olaquindox-induced hepatopancreas injury in jian carp (cyprinus carpio var. jian). | in order to identify effective hepatoprotective herbs for clinical application in fish farming, 200 mg/kg olaquindox (ola) was added to a basal diet (group 1, control) to form ola diet (group 2), then 1.35, 2.7 and 5.4 % (w/w) of a chinese herbal formulation, yingchen decoction (ycd), were added to the ola diet to form three additional diets for groups 3, 4 and 5, respectively. a total of 375 juvenile jian carp (cyprinus carpio var. jian) (52.12 ± 2.95 g/tail) were divided into five groups (trip ... | 2015 | 25477196 |
| improved methods for capture, extraction, and quantitative assay of environmental dna from asian bigheaded carp (hypophthalmichthys spp.). | indirect, non-invasive detection of rare aquatic macrofauna using aqueous environmental dna (edna) is a relatively new approach to population and biodiversity monitoring. as such, the sensitivity of monitoring results to different methods of edna capture, extraction, and detection is being investigated in many ecosystems and species. one of the first and largest conservation programs with edna-based monitoring as a central instrument focuses on asian bigheaded carp (hypophthalmichthys spp.), an ... | 2014 | 25474207 |
| impact of acute cd²⁺ exposure on the antioxidant defence systems in the skin and red blood cells of common carp (cyprinus carpio). | cd(2+)-induced oxidative stress and its effects on the expression of stress biomarkers and on macromolecule damage in the skin and blood of common carp were studied. both tissues play important roles in the defence mechanisms against external hazards, serving as an anatomical barrier and as connecting tissue between the organs. in the skin, the production of peroxynitrite anion and hydrogen peroxide was almost doubled after exposure to 10 mg/l cd(2+). the accumulation of these oxidant molecules ... | 2015 | 25471726 |
| analysis of mitochondrial respiratory-related genes reveals nuclear and mitochondrial genome cooperation in allotetraploid hybrid. | an allotetraploid hybrid lineage derived from the distant hybridization of red crucian carp (carassius auratus red var., ♀, 2n =100) × common carp (cyprinus carpio l., ♂, 2n =100) was investigated for its mitochondrial and nuclear genome inheritance patterns. based on liver transcriptomic data for this hybrid, red crucian carp, and common carp, we identified 94, 136, and 86 contigs corresponding to 41, 46, and 37 mitochondrial respiratory chain nuclear genes, respectively. mitochondrial respirat ... | 2014 | 25470286 |
| allopolyploidization is not so simple: evidence from the origin of the tribe cyprinini (teleostei: cypriniformes). | the identification of allopolyploidization events benefits from molecular dating and divergence assessments of progenitor genomes. information on gene duplications only, either orthologs or paralogs, provides incomplete information. analyses of mitochondrial dna yield insights into matrilineal history, which may differ from patrilineal evolution. two important food and pet fishes, the common carp (cyprinus carpio) and goldfish (carassius sp.), appear to have experienced allotetraploidization som ... | 2014 | 25470283 |
| species-specific preferences of german recreational anglers for freshwater fishing experiences, with emphasis on the intrinsic utilities of fish stocking and wild fishes. | to answer the question, whether anglers have an intrinsic preference for stocking or a preference for catch outcomes (e.g. catch rates) believed to be maintained by stocking, a discrete choice experiment was conducted among a sample of anglers (n = 1335) in lower saxony, germany. after controlling for catch aspects of the fishing experience, no significant influence of two stocking attributes (stocking frequency and composition of the catch in terms of wild v. hatchery fishes) on the utility gai ... | 2014 | 25469949 |
| phenolic endocrine-disrupting chemicals and intersex in wild crucian carp from hun river, china. | this study investigated the concentrations of phenolic endocrine-disrupting chemicals (edcs) and the incidence of ovo-testis (intersex) in wild crucian carp (carassius carassius) sampled from the hun river. as expected, nonylphenols (np) and bisphenol a (bpa) were detected in all samples, and octylphenols (op) were found in most samples. np concentrations ranged from 1290 ± 584 to 3111 ± 2071 ng g(-1) wet weight (ww) in july and from 1132 ± 644 to 1556 ± 587 ng g(-1) ww in november; op ranged fr ... | 2015 | 25465957 |
| effects and bioaccumulation of 17β-estradiol and 17α-ethynylestradiol following long-term exposure in crucian carp. | bioaccumulation and effects of 17β-estradiol (e2) and 17α-ethynylestradiol (ee2) were assessed by crucian carp (carassius auratus) following single and binary mixture exposures in flow-through exposure system for 16 months. in comparison with water control (dwc) and solvent control (sc), a significant reduction in body weight, body length and gonadosomatic index (gsi), and increase in hepatosomatic index (hsi) and plasma vitellogenin (vtg) levels were observed, in a time- and concentration-depen ... | 2015 | 25463868 |
| effect of different river flow rates on biomarker responses in common carp (cyprinus carpio). | the present study investigated effects of different river flow rates on basal activities of selected biomarkers and the occurrence of oxidative stress in the common carp (cyprinus carpio). juvenile carp were exposed to different river flow rates (5-120 cm/s) by caging for 3 weeks. after this period, one half of the fish were sacrificed and used for analysis. the other half received a single intraperitoneal injection of 3-methylcholanthrene (3-mc) and after 6 days were sacrificed and used for ana ... | 2015 | 25463866 |
| time and concentration dependency of macrogard® induced apoptosis. | in previous studies an effect of β-glucan on apoptosis in fish was noted and in this investigation we determine the time and concentration dependency of this effect. primary cell cultures of pronephric carp cells were incubated for 6, 24, 48 h with various concentrations ranging from 0 to 1000 μg/ml of macrogard(®) β-glucan. apoptosis was monitored via acridine orange staining. results indicate a clear effect of time and concentration on the induction of apoptosis in vitro, with only concentrati ... | 2015 | 25463286 |
| effect of dietary astaxanthin against aeromonas hydrophila infection in common carp, cyprinus carpio. | the effect of astaxanthin at 0, 25, 50, and 100 mg kg(-1) incorporated in basal feed on immune response and disease resistance in cyprinus carpio against aeromonas hydrophila was investigated. when fed with 25 mg kg(-1) diet, the cumulative mortality was 35% whereas it was 10% and 20% with 50 and 100 mg kg(-1) diets. with all enriched diets the growth rate increased significantly from week 1 to 4 when compared with control. however, the specific growth rate (sgr), feed conversion ratio (fcr), an ... | 2014 | 25462460 |
| biological uptake and depuration of sulfadiazine and sulfamethoxazole in common carp (cyprinus carpio). | sulfonamides, a class of the most commonly used antibiotics, are being increasingly released into the aquatic environment and have recently caused considerable concerns. however, knowledge on their fate and ecotoxicological effects upon aquatic organisms is not understood yet. this work investigated mainly the bioconcentration kinetics (uptake/depuration) of sulfadiazine (sdz) and sulfamethoxazole (smz) in common carp (cyprinus carpio) by exposure in different concentrations under semi-static co ... | 2015 | 25462302 |
| toxicological effects of clofibric acid and diclofenac on plasma thyroid hormones of an indian major carp, cirrhinus mrigala during short and long-term exposures. | in the present investigation, the toxicity of most commonly detected pharmaceuticals in the aquatic environment namely clofibric acid (ca) and diclofenac (dcf) was investigated in an indian major carp cirrhinus mrigala. fingerlings of c. mrigala were exposed to different concentrations (1, 10 and 100μgl(-1)) of ca and dcf for a period of 96h (short term) and 35 days (long term). the toxic effects of ca and dcf on thyroid hormones (ths) such as thyroid stimulating hormone (tsh), thyroxine (t4) an ... | 2014 | 25461555 |
| effects of atrazine and chlorpyrifos on dna methylation in the brain and gonad of the common carp. | dna methylation is known to play an important role in the regulation of gene expression in animal. the purpose of the present study was to examine the effect of atrazine (atr), chlorpyrifos (cpf) and combined atr/cpf exposure on dna methylation in the brain and gonad of common carp (cyprinus carpio l.). the carp were sampled after a 40-d exposure to cpf and atr, individually or in combination, followed by a 40-d recovery to measure the levels of global dna methylation and the expression of methy ... | 2015 | 25460047 |
| effect of butylated hydroxytoluene (bht) on the cryopreservation of common carp (cyprinus carpio) spermatozoa. | the aim of the present study was to test the effects of butylated hydroxytoluene (bht) on the cryopreservation of common carp spermatozoa. bht is widely used in the cryopreservation of the spermatozoa of different animal species and successfully sustains the characteristics of spermatozoa during freezing and thawing, but it has not previously been used with fish. after sampling, common carp spermatozoa were diluted with an extender composed of modified kurokura's extender, 10% dmso, and 10% egg ... | 2014 | 25459081 |
| effect of photoperiod on endocrine profiles and vitellogenin expression in european eels anguilla anguilla during artificially induced ovarian development. | the aim of this work was to determine the effects of dark and light conditions on the e2, testosterone and thyroid hormones levels and on the gene expression levels (vitellogenin 1, vitellogenin 2, and estradiol receptor one) in european eels (anguilla anguilla) during ovarian development induced by increasing doses of carp pituitary extracts (cpes). the subjects were divided into 2 groups: 14-hour light:10-hour dark (light group) and 24-hour darkness (dark group). all the eels received intramus ... | 2015 | 25459031 |
| production of inflammatory mediators and extracellular traps by carp macrophages and neutrophils in response to lipopolysaccharide and/or interferon-γ2. | neutrophilic granulocytes and macrophages are crucial for the innate immune response against infections. they migrate into the focus of inflammation, where they efficiently bind, engulf and kill bacteria by proteolytic enzymes, antimicrobial peptides, reactive oxygen (ros) and nitrogen (rns) species. moreover, activated neutrophils and macrophages can form extracellular traps (ets). fish neutrophils and macrophages are morphologically, histochemically, and functionally similar to their mammalian ... | 2015 | 25453727 |
| a cd46-like molecule functional in teleost fish represents an ancestral form of membrane-bound regulators of complement activation. | in the complement system, the regulators of complement activation (rca) play crucial roles in controlling excessive complement activation and in protecting host cell from misdirected attack of complement. several members of rca family have been cloned from cyclostome and bony fish species and classified into soluble and membrane-bound type as in mammalian rca factors. complement-regulatory functions have been described only for soluble rca of lamprey and barred sand bass; however, little is know ... | 2015 | 25452563 |
| effect of dietary isoleucine on the immunity, antioxidant status, tight junctions and microflora in the intestine of juvenile jian carp (cyprinus carpio var. jian). | this study was conducted to investigate the effects of dietary isoleucine (ile) on the immune response, antioxidant status, tight junctions, and microbial population in the intestine of juvenile jian carp (cyprinus carpio var. jian). a total of 1200 juvenile jian carp with average initial weight 6.9 ± 0.03 g were fed semi-purified isonitrogenous diets containing 4.2 (unsupplemented control group), 7.0, 9.5, 11.9, 13.9 and 16.9 g ile kg(-1) diet for 60 days. results indicated that ile supplementa ... | 2014 | 25451003 |
| water quality monitoring using abnormal tail-beat frequency of crucian carp. | fish are rapidly becoming favored as convenient sentinels for behavioral assays of toxic chemical exposure. tail-beat frequency (tbf) of fish is highly correlated with swimming speed, which has been used to detect toxicants. here we examined the effect on tbf of exposure to two chemicals, and evaluated the ability of this novel behavioral parameter to accurately monitor water quality. to further refine our approach, the wall-hitting rate (whr) was used to characterize behavioral avoidance after ... | 2015 | 25450932 |
| preparation of a polyclonal antibody against goldfish (carassius auratus) vitellogenin and its application to detect the estrogenic effects of monocrotophos pesticide. | goldfish (carassius auratus) represents a good model to detect the estrogenic effects of chemicals, and vitellogenin (vtg) is a vital indicator of estrogenic activity. the heterologous anti-carp vtg antibody has previously been used for goldfish vtg detection. here, we report the preparation of an anti-goldfish vtg antibody to improve the sensitivity and specificity of goldfish vtg immunoassays. vtg was purified from the plasma of 17β-estradiol (e2)-induced goldfish by gel filtration followed by ... | 2015 | 25450922 |
| increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling. | we investigated the cellular and molecular mechanisms of diastolic dysfunction in pure volume overload induced by aortocaval fistula (acf) surgery in the mouse. four weeks of volume overload resulted in significant biventricular hypertrophy; protein expression analysis in left ventricular (lv) tissue showed a marked decrease in titin's n2ba/n2b ratio with no change in phosphorylation of titin's spring region. titin-based passive tensions were significantly increased; a result of the decreased n2 ... | 2015 | 25450617 |
| data-analytical stability of cluster-wise and peak-wise inference in fmri data analysis. | carp (2012) demonstrated the large variability that is present in the method sections of fmri studies. this methodological variability between studies limits reproducible research. | 2015 | 25445059 |
| trans- and cis-urocanic acid, biogenic amine and amino acid contents in ikan pekasam (fermented fish) produced from javanese carp (puntius gonionotus) and black tilapia (oreochromis mossambicus). | ikan pekasam is a fermented fish product produced in malaysia and is usually made from freshwater fish with ground roasted uncooked rice as the main source of carbohydrate. in this study, the amino acid, biogenic amine, and trans- and cis-urocanic acid (uca) contents of fifteen commercial samples of ikan pekasam made from javanese carp and black tilapia, that had undergone either natural or acid-assisted fermentation, were quantified. the latter includes either tamarind (tamarindus indica) pulp ... | 2015 | 25442635 |
| investigation of the leptin levels in the blood serum of cyprinus carpio (linnaeus, 1758) and capoeta trutta (heckel, 1843). | leptin is a peptide hormone secreted by adipose tissues in the various teleost fish and vertebrates. leptin has been suggested to have an important role in a range physiological function, including regulation of food intake, reproduction, immune function, energy expenditure, lipid and carbohydrate metabolism. in this study, leptin levels in the blood serum of cyprinus carpio and capoeta trutta were determined. then the results were compared between two species and between sexes of each species. ... | 2015 | 25440001 |
| autoimmune features are associated with chronic antibiotic-refractory pouchitis. | chronic antibiotic-refractory pouchitis (carp) occurs more frequently in patients with ileal pouch-anal anastomosis (ipaa) with concomitant autoimmune disorders. the aim of this study was to assess the overlap between dysregulated immune features in patients with ipaa and their association with carp. | 2015 | 25437817 |
| immunological and histopathological responses of the kidney of common carp (cyprinus carpio l.) sublethally exposed to glyphosate. | glyphosate is a broad-spectrum herbicide frequently used world widely in agricultural and non-agricultural areas to control unwanted plants. health risk of chronic and subchronic exposure of glyphosate on animals and humans has received increasing attention in recent years. the aim of this study was to evaluate the effects of glyphosate on the immunoglobulin m (igm), complement c3 (c3), and lysozyme (lyz) in the kidney of common carp exposed to 52.08 or 104.15mgl(-1) of glyphosate for 168h. the ... | 2015 | 25434756 |