Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| bactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra. | cyclotides are a family of plant peptides characterized by a cystine knot embedded in a macrocyclic backbone. they bind to and disrupt phospholipid membranes, which explain their lytic activity on cells. in this study, we expose the full antibacterial potency of cyclotides by avoiding its inhibition by rich growth media assay conditions. for that purpose a two-step microdilution assay protocol was developed, using non-growing conditions during initial peptide incubation. a diverse set of cycloti ... | 2017 | 28669767 |
| evaluation of the bactericidal activity of telavancin against staphylococcus aureus using revised testing guidelines. | the in vitro broth microdilution testing method for telavancin, a lipoglycopeptide active against s. aureus, was revised in 2014 to include polysorbate-80 in the test media. this study evaluates the bactericidal activity of telavancin against s. aureus in media containing polysorbate-80 by in vitro time-kill analysis alongside relevant comparators. | 2017 | 28669676 |
| next generation dna sequencing of tissues from infected diabetic foot ulcers. | we used next generation dna sequencing to profile the microbiome of infected diabetic foot ulcers (dfus). the microbiota was correlated to clinical parameters and treatment outcomes to determine if directed antimicrobial therapy based on conventional microbiological cultures are relevant based on genomic analysis. patients≥18years presenting with a new diabetic foot infection (dfi) who had not received topical or oral antimicrobials in the two weeks prior to presentation, were eligible for enrol ... | 2017 | 28669650 |
| nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of japanese society of chemotherapy, the japanese association for infectious diseases, and the japanese society for clinical microbiology in 2012: general view of the pathogens' antibacterial susceptibility. | the nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from the patients in japan was conducted by japanese society of chemotherapy, japanese association for infectious diseases and japanese society for clinical microbiology in 2012. the isolates were collected from clinical specimens obtained from well-diagnosed adult patients with respiratory tract infections during the period between january and december in 2012 by three societies. antimicrobial suscept ... | 2017 | 28669567 |
| attenuating staphylococcus aureus virulence by targeting flotillin protein scaffold activity. | scaffold proteins are ubiquitous chaperones that bind proteins and facilitate physical interaction of multi-enzyme complexes. here we used a biochemical approach to dissect the scaffold activity of the flotillin-homolog protein floa of the multi-drug-resistant human pathogen staphylococcus aureus. we show that floa promotes oligomerization of membrane protein complexes, such as the membrane-associated rnase rny, which forms part of the rna-degradation machinery called the degradosome. cells lack ... | 2017 | 28669526 |
| cathelicidin production and release by mammary epithelial cells during infectious mastitis. | cathelicidins are well-characterized antimicrobial peptides (amps) that are present in significant amounts in mastitic milk. neutrophils are believed to be the main producers of these amps, while the role of mammary epithelial cells (mecs) in their production and release is still unclear. in this work, cathelicidin production patterns were investigated in mammary tissues of ewes infected by staphylococcus aureus, streptococcus uberis, or mycoplasma agalactiae, with a combined approach including ... | 2017 | 28669389 |
| antibiotic activity of emerimicin iv isolated from emericellopsis minima from talcahuano bay, chile. | due to the increasing emergence of resistance of bacterial pathogens to current antibiotics, we have examined the marine fungi present in sea sediments obtained 200 m offshore to discover new antibacterial compounds active against multidrug-resistant bacteria. one strain, identified as emericellopsis minima, was isolated from sediments of talcahuano bay (chile). from the liquid culture of e. minima, we isolated emerimicin iv, a unique fungal peptaibol that exhibited antibacterial activity. the s ... | 2017 | 28669240 |
| suppressive antibiotic therapy with oral doxycycline for staphylococcus aureus prosthetic joint infection: a retrospective study of 39 patients. | the aim of this study was to describe the use of oral doxycycline as suppressive antibiotic therapy (sat) in patients with staphylococcus aureus periprosthetic (hip or knee) joint infections. the medical charts of all patients with surgical revisions for s. aureus hip or knee prosthetic joint infections (pjis) who were given doxycycline-based sat because of a high risk of failure of various origins were reviewed. data regarding tolerability and effectiveness of doxycycline-based sat were analyse ... | 2017 | 28668689 |
| moxifloxacin plus rifampin as an alternative for levofloxacin plus rifampin in the treatment of a prosthetic joint infection with staphylococcus aureus. | the combination of a fluorquinolone with rifampin is one of the cornerstones in the treatment of a prosthetic joint infection (pji) caused by staphylococci. moxifloxacin is highly active against methicillin susceptible s. aureus (mssa), and therefore, an attractive agent to use. however, several studies reported a lowering in serum moxifloxacin levels when combined with rifampin. the clinical relevance remains unclear. we determined the outcome of patients with an early acute pji caused by mssa ... | 2017 | 28668678 |
| 10-valent pneumococcal conjugate vaccine (pcv10) decreases metabolic activity but not nasopharyngeal carriage of streptococcus pneumoniae and haemophilus influenzae. | the effect of pneumococcal vaccination is widely variable when measured by nasopharyngeal carriage of vaccine and non-vaccine targets. the aim of this study was to compare the carriage rates and metabolic activity of streptococcus pneumoniae, staphylococcus aureus, haemophilus influenzae and moraxella catarrhalis among children who were or were not vaccinated with pcv10. | 2017 | 28668567 |
| a fusion protein of the synthetic igg-binding domain and aequorin: expression and purification from e. coli cells and its application. | aequorin is a ca(2+)-binding photoprotein that is a complex of apoaequorin (apoaq) and 2-peroxycoelenterazine. in this study, the fusion protein (zz-apoaq) composed of the synthetic igg-binding domain (zz domain) derived from staphylococcus aureus protein a and apoaq was expressed into the periplasmic space of escherichia coli cells. zz-apoaq was highly purified using ni-chelate affinity chromatography followed by igg affinity chromatography. zz-aq was prepared from purified zz-apoaq by incubati ... | 2017 | 28668497 |
| identification of a pvl-negative sccmec-iva sublineage of the methicillin-resistant staphylococcus aureus cc80 lineage: understanding the clonal origin of ca-mrsa. | community-acquired (ca) methicillin-resistant staphylococcus aureus (mrsa) isolates belonging to clonal complex 80 (cc80) are recognized as the european ca-mrsa. the prevailing european ca-mrsa clone carries a type ivc staphylococcal cassette chromosome mec (sccmec) and expresses panton-valentine leukocidin (pvl). recently, a significant increase of pvl-negative cc80 mrsa has been observed in denmark. the aim of this study was to examine their genetics and epidemiology, and to compare them to th ... | 2017 | 28668467 |
| synthetic scale-up of a novel fluorescent probe and its biological evaluation for surface detection of staphylococcus aureus. | this paper reports on the lgx fluorometric test for enzymatic mrsa/mssa detection. it highlights the reasons rhodamines have been overlooked and also strategies to improve the synthesis of rhodamine-peptide conjugates. evaluation of the lgx test for detection of mrsa/mssa on surfaces is undertaken in the presence of potentially confounding e. coli and s. epidermidis for the first time. | 2017 | 28668278 |
| protein-protein interaction: tandem affinity purification in bacteria. | the discovery of protein-protein interaction networks can lead to the unveiling of protein complex(es) forming cellular machinerie(s) or reveal component proteins of a specific cellular pathway. deciphering protein-protein interaction networks therefore contributes to a deeper understanding of how cells function. here we describe the protocol to perform tandem affinity purification (tap) in bacteria, which enables the identification of the partners of a bait protein under native conditions. this ... | 2017 | 28667616 |
| a green strategy for the synthesis of sulfone derivatives of p-methylaminophenol: kinetic evaluation and antibacterial susceptibility. | this is one of the few examples in which the diverse products have been synthesized just by changing the applied potential. the synthesis of sulfonyl derivatives of p-methylaminophenol were carried out by reaction of the electrogenerated p-methylquinoneimine with sulfinic acids. various types of mono (msp), bis (bsp) and tris (tsp) sulfonyl p-methyl aminophenols were obtained by changing the electrode potential, in one pot under green conditions. the mono sulfonyl-p-(methylamino)phenol derivativ ... | 2017 | 28667267 |
| bacteriocins of non-aureus staphylococci isolated from bovine milk. | non-aureus staphylococci (nas), the bacteria most commonly isolated from the bovine udder, potentially protect the udder against infection by major mastitis pathogens due to bacteriocin production. in this study, we determined the inhibitory capability of 441 bovine nas isolates (comprising 26 species) against bovine staphylococcus aureus furthermore, inhibiting isolates were tested against a human methicillin-resistant s. aureus (mrsa) isolate using a cross-streaking method. we determined the p ... | 2017 | 28667105 |
| endogenous endophthalmitis and osteomyelitis associated with interleukin 17 inhibitor treatment for psoriasis in a patient with diabetes. | a 64-year-old man with type 2 diabetes mellitus and plaque psoriasis presented to the emergency room with 3 days of progressive right eye pain and decreased vision. after extensive workup and multidisciplinary team effort, the patient was diagnosed with and treated for unilateral endogenous methicillin-sensitive staphylococcus aureus endophthalmitis, bacteraemia and osteomyelitis of the foot. the patient had been started on the interleukin 17 (il-17) inhibitor secukinumab for his treatment-resis ... | 2017 | 28667056 |
| synthesis and characterization of zro2 nanoparticles-antimicrobial activity and their prospective role in dental care. | nanomaterials are exerting a pull on deal with biological and pharmaceutical applications. biomedical grade of zirconia reveals potential mechanical features of oxide ceramics. in this study, antimicrobial activity and anti-tooth decay applications of the synthesized nps of zro2 were determined. the as-prepared zro2 nps were characterized by uv-vis spectroscopy, ftir and xrd, which determined the formation of zro2nps and their crystalline nature. sem analysis further revealed spherical shaped np ... | 2017 | 28666841 |
| evaluation of sedation-related medication errors in contact isolation patients in the icu. | patients in the intensive care unit (icu), may be placed in contact isolation (ci) for meticillin-resistant staphylococcus aureus (mrsa) colonization to prevent transmission. prior studies suggest that isolated patients may receive substandard care compared to patients not on isolation. an optimal level of sedation is required to facilitate mechanical ventilation (mv) and to minimize adverse outcomes. | 2017 | 28666781 |
| impact of moving to a new hospital build, with a high proportion of single rooms, on healthcare-associated infections and outbreaks. | clostridium difficile infection, meticillin-sensitive staphylococcus aureus (mssa) and escherichia coli bacteraemia rates, and bed-days lost during norovirus outbreaks at north bristol nhs trust were analysed over a five-year period to determine whether moving to a new-build hospital with 75% single rooms reduced healthcare-associated infection rates. c. difficile, mssa bacteraemia and e. coli bacteraemia showed no change in the rate of decline after the move. bed-days lost due to norovirus were ... | 2017 | 28666780 |
| activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens. | there is a clear need for new antimicrobials to improve current treatment of chronic lung infection in people with cystic fibrosis (cf). this study determined the activities of antimicrobial peptides (amps) and ivacaftor, a novel cf transmembrane conductance regulator potentiator, for cf treatment. antimicrobial activities of amps [ll37, human β-defensins (hβd) 1-4 and slpi] and ivacaftor against clinical respiratory isolates (pseudomonas aeruginosa, staphylococcus aureus, streptococcus spp., ac ... | 2017 | 28666755 |
| recently approved antibacterials for methicillin-resistant staphylococcus aureus (mrsa) and other gram-positive pathogens: the shock of the new. | a number of novel antimicrobial drugs with activity against gram-positive bacterial pathogens have been licensed in the past 4 years. these drugs have the potential to enrich the group of intravenous drugs already available that are in common use against methicillin-resistant staphylococcus aureus (mrsa), vancomycin-resistant enterococci and other antibiotic-resistant gram-positive pathogens. the advantages and disadvantages of these drugs are not yet fully appreciated. here we review the five m ... | 2017 | 28666751 |
| soluble factors from biofilm of candida albicans and staphylococcus aureus promote cell death and inflammatory response. | the objective of this study was to better understand the effects of soluble factors from biofilm of single- and mixed-species candida albicans (c. albicans) and methicillin-sensitive staphylococcus aureus (mssa) cultures after 36 h in culture on keratinocytes (nok-si and hacat) and macrophages (j774a.1). soluble factors from biofilms of c. albicans and mssa were collected and incubated with keratinocytes and macrophages, which were subsequently evaluated by cell viability assays (mtt). lactate d ... | 2017 | 28666415 |
| prevalence of multidrug resistant bacteria in refugees: a prospective case control study in an obstetric cohort. | purpose to determine the prevalence of multidrug resistant (mdr) bacteria in a cohort of pregnant refugee women. methods in a prospective case control study, surveillance cultures for mdr bacteria (methicillin-resistant staphylococcus aureus [mrsa], vancomycin-resistant enterococci [vre], mdr gram-negative bacteria [mrgn]) were analysed between october 2015 and june 2016 from a cohort of 50 pregnant refugee women and 50 resident controls in the obstetric unit of a german tertiary referral hospit ... | 2017 | 28666305 |
| hplc-ms/ms targeted metabolic profiling reveals distinct metabolic profiles from staphylococcus aureus small-colony variants. | staphylococcus aureus is a world-wide health threat due to its prevalence and possible resistance to antibiotic treatment. a variety reasons can contribute to s. aureus antibiotic resistance and one group of phenotypes that may be discovered from s. aureus is named small-colony variants (scvs). this study focused on applying a hplc-ms/ms based targeted metabolic profiling approach to detect a set of metabolites that are dysregulated during s. aureus scvs formation. over one hundred and eighty me ... | 2017 | 28666225 |
| molecular mechanics of staphylococcus aureus adhesin, cna, and the inhibition of bacterial adhesion by stretching collagen. | bacterial adhesion to collagen, the most abundant protein in humans, is a critical step in the initiation and persistence of numerous bacterial infections. in this study, we explore the collagen binding mechanism of the multi-modular cell wall anchored collagen adhesin (cna) in staphylococcus aureus and examine how applied mechanical forces can modulate adhesion ability. the common structural-functional elements and domain organization of cna are present across over 50 genera of bacteria. throug ... | 2017 | 28665944 |
| septic arthritis of the shoulder: a comparison of treatment methods. | in-hospital outcomes were compared among patients with shoulder septic arthritis treated with arthrocentesis, open irrigation and débridement, or arthroscopic irrigation and débridement. | 2017 | 28665804 |
| surveillance of bacterial colonisation on contact surfaces in different medical wards. | this study was conducted to determine the bacterial colonization of some bacterial groups, including extended-spectrum β-lactamase (esbls) producers and methicillin-resistant staphylococcus aureus (mrsa), on surfaces of the equipment and instruments in patient rooms and other workspaces in three different medical wards. the number of microorganisms on swabs was determined with the colony count method on selective microbiological mediums. the aerobic mesophylic microorganisms were found in 73.5 % ... | 2017 | 28665797 |
| isolation and characterization of sesquiterpenoids from cassia buds and their antimicrobial activities. | cassia buds, the immature fruits of cinnamomum cassia (lauraceae), are widely consumed as a food spice, dietary supplements, flavoring agents, and preservatives. in this study, cassia buds were phytochemically investigated for the first time, leading to the isolation of 2 new sesquiterpenoids (1 and 2) and 10 known sesquiterpenoids (3-12). their structures were determined by spectrometric and spectroscopic analyses, including nuclear magnetic resonance, high-resolution electrospray ionization ma ... | 2017 | 28665598 |
| prophylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases. | objective wound infections following spinal surgery for deformity place a high toll on patients, providers, and the health care system. the prophylactic application of intraoperative vancomycin powder has been shown to lower the infection risk after thoracolumbar decompression and fusion for deformity correction. the purpose of this study was to assess the microbiological patterns of postoperative surgical site infections (ssis) after prophylactic use of vancomycin powder in adult patients under ... | 2017 | 28665245 |
| how do fluorescence spectroscopy and multimodal fluorescence imaging help to dissect the enhanced efficiency of the vancomycin-rifampin combination against staphylococcus aureus infections? | staphylococcus aureus is one of the most frequent pathogens responsible for biofilm-associated infections. among current clinical antibiotics, very few enable long-term successful treatment. thus, it becomes necessary to better understand antibiotic failures and successes in treating infections in order to master the use of proper antibiotic therapies. in this context, we took benefit from a set of fluorescence spectroscopy and imaging methods, with the support of conventional microbiological to ... | 2017 | 28664201 |
| data on the surface morphology of additively manufactured ti-6al-4v implants during processing by plasma electrolytic oxidation. | additively manufactured ti-6al-4v implants were biofunctionalized using plasma electrolytic oxidation. at various time points during this process scanning electron microscopy imaging was performed to analyze the surface morphology (van hengel et al., 2017) [1]. this data shows the changes in surface morphology during plasma electrolytic oxidation. data presented in this article are related to the research article "selective laser melting porous metallic implants with immobilized silver nanoparti ... | 2017 | 28664174 |
| potentiating antimicrobial efficacy of propolis through niosomal-based system for administration. | propolis is a multicomponent active, complex resinous substance collected by honeybees (apis mellifera) from a variety of plant sources. this study was designed to improve the antimicrobial efficacy of propolis by engineering a niosomal-based system for topical application. | 2015 | 28664114 |
| antimicrobial and cytotoxic evaluation of some herbal essential oils in comparison with common antibiotics in bioassay condition. | since ancient times, various infectious diseases have been treated using herbal drugs. today, efforts regarding the discovery of the effectual components of plants possessing antimicrobial properties are advanced. herbal essential oils are widely used for treatment of various diseases, and they play an important role in health care considerations. | 2014 | 28664090 |
| monitoring in vitro antibacterial efficacy of 26 indian spices against multidrug resistant urinary tract infecting bacteria. | to screen methanolic extracts of 26 commonly used indian spices against nine species of uropathogenic bacteria (enterococcus faecalis, staphylococcus aureus, acinetobacter baumannii, citrobacter freundii, enterobacter aerogenes, escherichia coli, klebsiella pneumoniae, proteus mirabilis, and pseudomonas aeruginosa), isolated from clinical samples of a tertiary care hospital for antibacterial activity. | 2014 | 28664089 |
| skin infection caused by a novel strain of staphylococcus pseudintermedius in a siberian husky dog owner. | introduction.staphylococcus pseudintermedius, an opportunistic pathogen of dogs and cats, is rarely reported to cause infection in humans. here, we describe a case of severe skin infection caused by s. pseudintermedius, in a 47-year-old male, a dog owner; to the best of our knowledge, this is the first such case reported from scotland. case presentation. the patient presented with a short history of a severe ecthyma-like lesion on his forehead, with smaller lesions on his abdomen and legs. bacte ... | 2017 | 28663821 |
| septic arthritis caused by an emerging st121 methicillin-susceptible, pvl-negative staphylococcus aureus harbouring a variant of bone sialoprotein-binding protein gene. | st121/agr-iv methicillin-susceptible staphylococcus aureus was isolated from a patient of septic arthritis (synovial fluid, blood, skin and nasal cavity). although the panton-valentine leukocidin (pvl) gene was negative, this isolate harboured a gene encoding a variant of bone sialoprotein-binding protein with a shortened sd-repeat region. | 2017 | 28663800 |
| identification of tigecycline- and vancomycin-resistant staphylococcus aureus strains among patients with urinary tract infection in iran. | methicillin-resistant staphylococcus aureus (mrsa) is one of the major causes of hospital- and community-acquired infections worldwide. although s. aureus rarely accounts for urinary tract infections (uti), untreated uti can lead to several complications. for decades vancomycin has been used for the treatment of mrsa infections. this study was performed to assess the in vitro activity of vancomycin, tigecycline, linezolid and quinupristin/dalfopristin against mrsa isolates from uti patients. thi ... | 2017 | 28663797 |
| infection prophylaxis for breast implant surgery: could we do better? | objective: infective complications following breast implant surgery may result in implant removal. this causes patient distress and is costly to treat. a range of precautions is undertaken at the time of surgery to reduce infection, with varying levels of supporting evidence. this study aimed to determine how frequently and consistently infection prevention precautions are used during breast implant surgery. methods: multicenter observational study of surgical practice with real-time data collec ... | 2017 | 28663774 |
| successful management of above knee amputation with combined and modified nerve blocks. | we report a successful management of a case of methicillin-resistant staphylococcus aureus positive right lower limb cellulitis for above knee amputation under combined nerve blocks. the ongoing sepsis, thrombocytopenia, and severe respiratory infection with wheeze made us avoid both neuraxial block and general anesthesia and plan for a nerve block. we instituted a modified high inguinal femoral block along with sciatic and lateral femoral nerve blocks separately to successfully conduct the case ... | 2017 | 28663654 |
| national healthcare safety network (nhsn) dialysis event surveillance report for 2014. | persons receiving outpatient hemodialysis are at risk for bloodstream and vascular access infections. the centers for disease control and prevention conducts surveillance for these infections through the national healthcare safety network. we summarize 2014 data submitted to national healthcare safety network dialysis event surveillance. | 2017 | 28663227 |
| thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis. | the aim of the present study was to develop thermoplastic polyurethane (tpu)-based intravaginal rings (ivrs) for prophylaxis and treatment of bacterial vaginosis via hot melt extrusion/injection molding. therefore, different tpu grades were processed in combination with lactic acid or metronidazole, targeting a sustained lactic acid release over a 28day-period and sustained metronidazole release over 4-7days. hot melt extrusion of lactic acid/tpu combinations required a lower extrusion temperatu ... | 2017 | 28663088 |
| the influence of experimental conditions on the final result of photoinhibition of staphylococcus aureus. | by and large, phototherapies are a promising approach to promote inactivation of microorganisms using light exposure, providing an effective alternative to control multidrug-resistant bacterial infections. considering this, intercomparison between experiments is vitally important. most experiments are performed using multiwell plates in which the volume of the culture medium is not standardized. in such cases, light attenuation and the distance it travels, which also depends on the volume and ve ... | 2017 | 28662923 |
| panton-valentine leukocidin-producing staphylococcus aureus infection of the neck that mimicked disseminated malignancy. | 2017 | 28662921 | |
| a discrete event simulation model of patient flow in a general hospital incorporating infection control policy for methicillin-resistant staphylococcus aureus (mrsa) and vancomycin-resistant enterococcus (vre). | hospitalized patients are assigned to available staffed beds based on patient acuity and services required. in hospitals with double-occupancy rooms, patients must be additionally matched by gender. patients with methicillin-resistant staphylococcus aureus (mrsa) or vancomycin-resistant enterococcus (vre) must be bedded in single-occupancy rooms or cohorted with other patients with similar mrsa/vre flags. | 2017 | 28662601 |
| three new abietane-type diterpenoids from plectranthus africanus and their antibacterial activities. | three new abietane-type diterpenoids, plectranthroyleanones a - c (1 - 3), together with five known compounds (4 - 8) were isolated from the methanol extract of the whole plant of plectranthus africanus using column chromatography techniques. the structures of the new compounds were elucidated using a combination of 1d and 2d nmr and hresims analyses. compound 1 exhibited weak activities with minimal inhibitory concentration values of 75 µg/ml against gram-positive bacteria, bacillus subtilis an ... | 2017 | 28662528 |
| innovative non-thermal plasma disinfection process inside sealed bags: assessment of bactericidal and sporicidal effectiveness in regard to current sterilization norms. | in this work, we developed a device capable to generate a non-thermal plasma discharge inside a sealed bag. the aim of this study was to assess the effectiveness of the oxygen, nitrogen and argon plasma sterilization on pseudomonas aeruginosa, staphylococcus aureus and bacillus subtilis spores according to the nf en 556 norm. moreover the bag integrity which is a critical key to maintain the sterile state of items after the end of the process was verified by fourier transform infrared (ftir) and ... | 2017 | 28662202 |
| fluoro-carba-sugars are glycomimetic activators of the glms ribozyme. | the glms ribozyme is a bacterial gene-regulating riboswitch that controls cell wall synthesis, depending on glucosamine-6-phosphate as a cofactor. due to the presence of this ribozyme in several human pathogen bacteria (e.g. mrsa, vrsa), the glms ribozyme represents an attractive target for the development of artificial cofactors. the substitution of the ring oxygen in carbohydrates by functionalized methylene groups leads to a new generation of glycomimetics that exploits distinct interaction p ... | 2017 | 28661578 |
| prevalence of methicillin-resistant staphylococcus aureus from equine nasopharyngeal and guttural pouch wash samples. | methicillin-resistant staphylococcus aureus (mrsa) is recognized as a cause of nosocomial infections in both human and veterinary medicine. studies that examine the nasopharynx and guttural pouches of the horse as carriage sites for mrsa have not been reported. | 2017 | 28661019 |
| the role of antimicrobial sutures in preventing surgical site infection. | introduction healthcare associated infections (hcais) are falling following widespread and enforced introduction of guidelines, particularly those that have addressed antibiotic resistant pathogens such as methicillin resistant staphylococcus aureus or emergent pathogens such as clostridium difficile, but no such decline has been seen in the incidence of surgical site infection (ssi), either in the uk, the eu or the us. ssi is one of the hcais, which are all avoidable complications of a surgical ... | 2017 | 28660816 |
| plant-derived antimicrobials to fight against multi-drug-resistant human pathogens. | antibiotic resistance is becoming a pivotal concern for public health that has accelerated the search for new antimicrobial molecules from nature. numbers of human pathogens have inevitably evolved to become resistant to various currently available drugs causing considerable mortality and morbidity worldwide. it is apparent that novel antibiotics are urgently warranted to combat these life-threatening pathogens. in recent years, there have been an increasing number of studies to discover new bio ... | 2017 | 28660459 |
| the immunomodulatory effect of trichophyton rubrum exoantigens in the treatment of experimental septic arthritis. | understanding the nature and function of fungal exoantigens might lead to novel approaches in the treatment and prophylaxis of some infectious diseases. septic arthritis represents a serious problem for medicine due to the high incidence rate and severe complications. | 2017 | 28659996 |
| pterostilbene, a methoxylated resveratrol derivative, efficiently eradicates planktonic, biofilm, and intracellular mrsa by topical application. | pterostilbene is a methoxylated derivative of resveratrol originated from natural sources. we investigated the antibacterial activity of pterostilbene against drug-resistant staphylococcus aureus and the feasibility of using it to treat cutaneous bacteria. the antimicrobial effect was evaluated using an in vitro culture model and an in vivo mouse model of cutaneous infection. the minimum inhibitory concentration (mic) assay demonstrated a superior biocidal activity of pterostilbene compared to r ... | 2017 | 28659908 |
| antimicrobial potential of bacteria associated with marine sea slugs from north sulawesi, indonesia. | nudibranchia, marine soft-bodied organisms, developed, due to the absence of a protective shell, different strategies to protect themselves against putative predators and fouling organisms. one strategy is to use chemical weapons to distract predators, as well as pathogenic microorganisms. hence, these gastropods take advantage of the incorporation of chemical molecules. thereby the original source of these natural products varies; it might be the food source, de novo synthesis from the sea slug ... | 2017 | 28659904 |
| rapid phenotypic detection of microbial resistance in gram-positive bacteria by a real-time laser scattering method. | we developed a methodology for antimicrobial susceptibility testing (ast) based on the bacterioscan(tm)216r laser scattering technology, using methicillin resistance in staphylococcus aureus and vancomycin resistance in enterococci as exemplar for important resistance phenotypes. fifty methicillin-resistant (mrsa) and 50 methicillin-susceptible (mssa) s. aureus, as well as 50 vancomycin-resistant enterococci (vre) and 50 vancomycin-susceptible enterococci (vse) isolates were used for the study. ... | 2017 | 28659889 |
| nutritional strategies and gut microbiota composition as risk factors for necrotizing enterocolitis in very-preterm infants. | background: the pathophysiology of necrotizing enterocolitis (nec) remains poorly understood.objective: we assessed the relation between feeding strategies, intestinal microbiota composition, and the development of nec.design: we performed a prospective nationwide population-based study, epipage 2 (etude epidémiologique sur les petits ages gestationnels), including preterm infants born at <32 wk of gestation in france in 2011. from individual characteristics observed during the first week of lif ... | 2017 | 28659297 |
| chemical composition and antimicrobial activity of the essential oil of mentha mozaffarianii jamzad growing wild and cultivated in iran. | the aerial parts of wild and cultivated mentha mozaffarianii jamzad were collected at full flowering stage from two provinces (hormozgan and fars) of iran. the essential oils were extracted by a clevenger approach and analysed using gc and gc-ms. the main components in wild plants were piperitenone (33.85%), piperitone (21.18%), linalool (6.89%), pulegone (5.93%), 1, 8.cineole (5.49%), piperitenone oxide (5.17%) and menthone (4.69%) and in cultivated plants, cis-piperitone epoxide (28.89%), lina ... | 2017 | 28658991 |
| a placebo-controlled trial of antibiotics for smaller skin abscesses. | uncomplicated skin abscesses are common, yet the appropriate management of the condition in the era of community-associated methicillin-resistant staphylococcus aureus (mrsa) is unclear. | 2017 | 28657870 |
| hematologic complications in a patient with glycine soja polyagglutination following fresh frozen plasma transfusion. | polyagglutination is a rare and underdiagnosed condition, characterized by agglutination of red blood cells(rbcs) with almost all abo-compatible adult sera. polyagglutination can occur when a cryptantigen is exposed on rbcs via microbial enzyme activity. becausenearly all adults naturally produce antibodies against cryptantigens, transfusion of plasma can cause unexpected hemolysis and hematologic complications, such as thrombocytopenia and disseminated intravascular coagulation, in patients who ... | 2017 | 28657762 |
| epidermal growth factor receptor signaling enhances the proinflammatory effects of staphylococcus aureus gamma-toxin on the mucosa. | staphylococcus aureus (s. aureus) produces many different exotoxins including the gamma-toxins, hlgab and hlgcb. gamma-toxins form pores in both leukocyte and erythrocyte membranes, resulting in cell lysis. the genes encoding gamma-toxins are present in most strains of s. aureus, and are commonly expressed in clinical isolates recovered from menstrual toxic shock syndrome (mtss) patients. this study set out to investigate the cytotoxic and proinflammatory effects of gamma-toxins on vaginal epith ... | 2017 | 28657583 |
| self-sterilizing sputtered films for applications in hospital facilities. | this review addresses the preparation of antibacterial 2d textile and thin polymer films and 3d surfaces like catheters for applications in hospital and health care facilities. the sputtering of films applying different levels of energy led to the deposition of metal/oxide/composite/films showing differentiated antibacterial kinetics and surface microstructure. the optimization of the film composition in regards to the antibacterial active component was carried out in each case to attain the fas ... | 2017 | 28657579 |
| mapping quorum sensing onto neural networks to understand collective decision making in heterogeneous microbial communities. | microbial communities frequently communicate via quorum sensing (qs), where cells produce, secrete, and respond to a threshold level of an autoinducer (ai) molecule, thereby modulating gene expression. however, the biology of qs remains incompletely understood in heterogeneous communities, where variant bacterial strains possess distinct qs systems that produce chemically unique ais. ai molecules bind to 'cognate' receptors, but also to 'non-cognate' receptors found in other strains, resulting i ... | 2017 | 28656904 |
| a network model of hand hygiene: how good is good enough to stop the spread of mrsa? | background simulation models have been used to investigate the impact of hand hygiene on methicillin-resistant staphylococcus aureus (mrsa) transmission within the healthcare setting, but they have been limited by their ability to accurately model complex patient-provider interactions. methods using a network-based modeling approach, we created a simulated neonatal intensive care unit (nicu) representing the potential for per-hour infant-infant mrsa transmission via the healthcare worker resulti ... | 2017 | 28656884 |
| parenteral irons versus transfused red blood cells for treatment of anemia during canine experimental bacterial pneumonia. | no studies have been performed comparing intravenous (iv) iron with transfused red blood cells (rbcs) for treating anemia during infection. in a previous report, transfused older rbcs increased free iron release and mortality in infected animals when compared to fresher cells. we hypothesized that treating anemia during infection with transfused fresh rbcs, with minimal free iron release, would prove superior to iv iron therapy. | 2017 | 28656646 |
| heparin mimics extracellular dna in binding to cell surface-localized proteins and promoting staphylococcus aureus biofilm formation. | staphylococcus aureus is a leading cause of catheter-related bloodstream infections. biofilms form on these implants and are held together by a matrix composed of proteins, polysaccharides, and extracellular dna (edna). heparin is a sulfated glycosaminoglycan that is routinely used in central venous catheters to prevent thrombosis, but it has been shown to stimulate s. aureus biofilm formation through an unknown mechanism. data presented here reveal that heparin enhances biofilm capacity in many ... | 2017 | 28656173 |
| sulfide homeostasis and nitroxyl intersect via formation of reactive sulfur species in staphylococcus aureus. | staphylococcus aureus is a commensal human pathogen and a major cause of nosocomial infections. as gaseous signaling molecules, endogenous hydrogen sulfide (h2s) and nitric oxide (no·) protect s. aureus from antibiotic stress synergistically, which we propose involves the intermediacy of nitroxyl (hno). here, we examine the effect of exogenous sulfide and hno on the transcriptome and the formation of low-molecular-weight (lmw) thiol persulfides of bacillithiol, cysteine, and coenzyme a as repres ... | 2017 | 28656172 |
| vancomycin resistance in staphylococcus aureus . | the evolution of staphylococcus aureus during the modern antibiotic era has been delineated by distinct strain emergence events, many of which include acquisition of antibiotic resistance. the relative high burden of methicillin-resistant s. aureus (mrsa) in healthcare and community settings is a major concern worldwide. vancomycin, a glycopeptide antibiotic that inhibits cell wall biosynthesis, remains a drug of choice for treatment of severe mrsa infections. s. aureus strains exhibiting increa ... | 2017 | 28656013 |
| emergence and spread of antibiotic resistance in west africa : contributing factors and threat assessment. | the emergence and spread of antibiotic resistance present a major public health issue in both developed (dc) and less developed countries (ldc). worldwide, its main cause is the uncontrolled and unjustified use of antibiotics. in countries with limited resources, such as west african nations, other features, more specifically socioeconomic and behavioral factors, contribute to exacerbate this problem. the objective of this review is to give an update of the common and specific factors involved i ... | 2017 | 28655675 |
| genetic diversity of pvl-positive community-onset methicillin-resistant staphylococcus aureus isolated at a university hospital in japan. | community-acquired methicillin-resistant staphylococcus aureus (ca-mrsa) is pathogenic to healthy individuals and a significant issue throughout the world. panton-valentine leukocidin gene (pvl)-positive sequence type (st) 8-staphylococcal cassette chromosome (scc) mec type iv (st8-iv) as represented by the usa300 clone, is the most prevalent ca-mrsa in many countries. however, the prevalence of pvl-positive ca-mrsa was limited in japan. here, we report the incidence of pvl-positive community-on ... | 2017 | 28655502 |
| keratinocytes as sensors and central players in the immune defense against staphylococcus aureus in the skin. | healthy human skin provides an effective mechanical as well as immunologic barrier against pathogenic microorganisms with keratinocytes as the main cell type in the epidermis actively participating and orchestrating the innate immune response of the skin. as constituent of the outermost layer encountering potential pathogens they have to sense signals from the environment and must be able to initiate a differential immune response to harmless commensals and harmful pathogens. staphylococci are a ... | 2017 | 28655473 |
| synthesis and antibacterial activity of novel 4″-o-(1-aralkyl-1,2,3-triazol-4-methyl-carbamoyl) azithromycin analogs. | three novel structural series of 4″-o-(1-aralkyl-1,2,3-triazol-4-methyl-carbamoyl) azithromycin analogs were designed, synthesized and evaluated for their in vitro antibacterial activity. all the target compounds exhibited excellent activity against erythromycin-susceptible streptococcus pyogenes, and significantly improved activity against three phenotypes of erythromycin-resistant streptococcus pneumoniae compared with clarithromycin and azithromycin. among the three series of azithromycin ana ... | 2017 | 28655423 |
| evaluation of factors associated with the achievement of an optimal teicoplanin trough concentration . | because teicoplanin has a long serum half-life, a longer period of time is needed to achieve a steady-state concentration compared with vancomycin. the administration of an initial loading dose has been recommended to reach an effective teicoplanin serum concentration for the treatment of methicillin-resistant <italic>staphylococcus aureus</italic> (mrsa). however, little is known regarding factors that affect teicoplanin concentration. this study aimed to retrospectively determine which factors ... | 2017 | 28655381 |
| growth-dependent activity of the cold shock cspa promoter + 5' utr and production of the protein cspa in staphylococcus aureus newman. | research involving the cold shock gene cspa of the medically important bacterium staphylococcus aureus is steadily increasing as the relationships between the activity of this gene at 37 °c and a spectrum of virulence factors (e.g., biofilm formation, capsule production) as well as stress-related genes (e.g., alkaline shock protein, asp-23 and the alternative sigma factor, sigb) are distinguished. fundamental to each of these discoveries is defining the regulation of cspa and the production of i ... | 2017 | 28655334 |
| assessment of staphylococcus aureus along milk value chain and its public health importance in sebeta, central oromia, ethiopia. | staphylococcus aureus is one of the leading causes of gastroenteritis acquired from contaminated foods such as milk and milk products. however, such information is limited in ethiopia. a cross-sectional study was conducted to assess the contamination of milk with s. aureus and knowledge, attitudes and practices (kap) of actors along the milk value chain in sebeta, central oromia, ethiopia. a total of 291 samples collected from dairy farms, milk collection centers (mccs) and processing plant were ... | 2017 | 28655298 |
| specific and selective probes for staphylococcus aureus from phage-displayed random peptide libraries. | staphylococcus aureus is a major human pathogen causing health care-associated and community-associated infections. early diagnosis is essential to prevent disease progression and to reduce complications that can be serious. in this study, we selected, from a 9-mer phage peptide library, a phage clone displaying peptide capable of specific binding to s. aureus cell surface, namely st.au9ivs5 (sequence peptide rvrsapsss).the ability of the isolated phage clone to interact specifically with s. aur ... | 2017 | 28654884 |
| evidence for the presence of cell-surface-bound and intracellular bactericidal toxins in the dinoflagellate heterocapsa circularisquama. | heterocapsa circularisquama, a harmful dinoflagellate, has multiple haemolytic toxins that are considered to be involved in the toxic mechanism against shellfish and certain species of zooplankton. to evaluate the further nature of the toxins of h. circularisquama, we investigated its effects on several species of bacteria. by colony formation assay, we found that h. circularisquama had antibacterial activity toward the marine bacterium vibrio alginolyticus in a cell density-dependent manner. wh ... | 2017 | 28654772 |
| estimating the disease burden of methicillin-resistant staphylococcus aureus in japan: retrospective database study of japanese hospitals. | the nationwide impact of antimicrobial-resistant infections on healthcare facilities throughout japan has yet to be examined. this study aimed to estimate the disease burden of methicillin-resistant staphylococcus aureus (mrsa) infections in japanese hospitals. | 2017 | 28654675 |
| a bright future for antibiotics? | multidrug resistance is a global threat as the clinically available potent antibiotic drugs are becoming exceedingly scarce. for example, increasing drug resistance among gram-positive bacteria is responsible for approximately one-third of nosocomial infections. as ribosomes are a major target for these drugs, they may serve as suitable objects for novel development of next-generation antibiotics. three-dimensional structures of ribosomal particles from staphylococcus aureus obtained by x-ray cr ... | 2017 | 28654325 |
| ultralong hydroxyapatite nanowires-based paper co-loaded with silver nanoparticles and antibiotic for long-term antibacterial benefit. | hydroxyapatite is a kind of biocompatible, environmentally friendly, and versatile inorganic biomaterial. herein, the preparation of ultralong hydroxyapatite nanowires (hapnws)-based antibacterial paper co-loaded with silver nanoparticles (agnps) and antibiotic is reported. hapnws are used to prepare agnps in situ using an aqueous solution containing agno3 under the sunlight without added reducing agent at room temperature. subsequently, ciprofloxacin (cip) as an antibiotic is loaded on the hapn ... | 2017 | 28654270 |
| labradorins with antibacterial activity produced by pseudomonas sp. | the urgent need for new antibacterial drugs has led to renewed interest in microorganisms, which historically have been the main source of previously discovered antibiotics. the present study describes the discovery of two new antibacterial oxazolylindole type alkaloids, labradorins 5 (1) and 6 (2), which were isolated and characterized from two isolates of pseudomonas sp., along with four previously known tryptophane derived alkaloids. the structures of 1 and 2 were determined by nmr spectrosco ... | 2017 | 28654009 |
| exploitation of spr to investigate the importance of glycan chains in the interaction between lactoferrin and bacteria. | bovine lactoferrin (lf) has been shown to prevent adhesion to and invasion of mammalian cell lines by pathogenic bacteria, with evidence for direct bacterial binding by the milk glycoprotein. however, the glycosylation pattern of lf changes over the lactation cycle. in this study, we aim to investigate the effect that this variation has on the milk glycoprotein's ability to interact with pathogens. surface plasmon resonance technology was employed to compare the binding of lf from colostrum (ear ... | 2017 | 28653977 |
| impact of bovine and human serum albumin on curcumin in vitro activity against staphylococcus aureus. | this study evaluated the impact of ph (7.4 and 6.5), bovine serum albumin (bsa), and human serum albumin (hsa) on curcumin activity against 2 reference, 1 clinical, and 10 environmental strains of staphylococcus aureus (s. aureus). minimal inhibitory concentrations (mics) of curcumin against s. aureus were statistically indifferent (p>0.05) at ph7.4 and ph6.5. activity of curcumin against s. aureus was reduced by two folds in the presence of 1.25-5% bsa/hsa. | 2017 | 28653935 |
| identification and growth optimization of a marine bacillus dk1-sa11 having potential of producing broad spectrum antimicrobial compounds. | control of harmful bacteria in food, aquaculture, pharmaceuticals, agriculture, hospitals and recreation water pools are of great global concern. marine bacteria are an enormous source of bio-controlling agents. the aim of this study was to identify and optimize the growth conditions including effect of different biotic and abiotic factors on antimicrobial activity of strain dk1-sa11 isolated from qingdao bay of china yellow sea. microscopic characterization, api® 20e and 50 chb kit base carbohy ... | 2017 | 28653930 |
| screening of leaves extracts from calamus aromaticus for their antimicrobial activity by disc diffusion assay. | the current research investigates the anti-microbial activities of different solvent extracted samples from the leaves of calamus aromaticus against gram positive, gram negative bacteria and fungi using 500, 1000 and 2000 μg disc(-1) concentrations. escherichia coli, citorbacter freundii and candida albicans showed resistivity to crude methanolic extract and the same microbes were more susceptible to water extracted fractions. maximum activity was measured by hexane extracted fractions against p ... | 2017 | 28653924 |
| kitchen phytochemicals from allium cepa - their role in multidrug resistance. | bacterial resistance to antibiotics is increasingly becoming a concern to public health. current antibiotics have failed to bring desirable results to many bacterial infections due to multi-resistant strains. so, concerted efforts are being made to curve this with the help of dietary phytohemicals. a number of dietary phytochemical are being put to trials for antimicrobial activity; however it is worthwhile to search such a part of diet that is very frequently used by major population. keeping t ... | 2017 | 28653923 |
| antibacterial and antioxidant properties of various solvents extracts of abutilon theophrasti medic. leaves. | this paper described the extraction procedure of six extracts from abutilon theophrasti medic. leaves and evaluated antioxidant and antibacterial activity of different extracts by hydroxyl radical, dpph radical scavenging, broth micro-dilution and agar-well diffusion methods. the six extracts were prepared by the two extraction procedures: (i) water was the extraction solvent; (ii) 90% alcohol extract was extracted by petroleum ether, chloroform, ethyl acetate and n-butanol in turn. extract yiel ... | 2017 | 28653920 |
| biological activities of allium sativum and zingiber officinale extracts on clinically important bacterial pathogens, their phytochemical and ft-ir spectroscopic analysis. | the spread of bacterial infectious diseases is a major public threat. herbs and spices have offered an excellent, important and useful source of antimicrobial agents against many pathological infections. in the current study, the antimicrobial potency of fresh, naturally and commercial dried allium sativum and zingiber officinale extracts had been investigated against seven local clinical bacterial isolates such as escherichia coli, pseudomonas aeruginosa, klebsiella pneumonia, staphylococcus au ... | 2017 | 28653916 |
| evaluation of anti-oxidative, antimicrobial and anti-diabetic potential of adiantum venustum and identification of its phytochemicals through gc-ms. | the present study aimed to explore antioxidant, antimicrobial and anti-diabetic properties of the fern adiantum venustum. the tpc (total phenolic content) of methanolic extract of the plant was 247.95±0.0007μg of gallic acid equivalents per gram of dried extract (mg gae/g). the highest tpc was in n-butanolic fraction, which was 981.45±0.1562mg gae/g. hexane fraction showed lowest tpc (256.95±0.0420mg gae/g). ethyl acetate fraction exhibited highest total flavonoid content (tfc), i.e., 62.0±0.050 ... | 2017 | 28653913 |
| residual risk of bacterial contamination of platelets: six years of experience with sterility testing. | canadian blood services screens 100% of platelet concentrates (pcs) for bacterial contamination with the bact/alert system. quality-control sterility testing of 1% (≥10 units) of outdated pcs is performed monthly. data from routine screening, quality-control testing, and septic reactions obtained from 2010 to 2016 are presented herein. | 2017 | 28653472 |
| identification of set11 from staphylococcus aureus mu50 strain as a ortholog of ssl7 via bioinformatic analysis and determination of its possible targets from human serum using cnbr-pull down assays. | to identify and characterize staphylococcus exotoxin-like (set) protein set11 from staphylococcus aureus mu50 strain and its possible targets proteins from human blood/serum. | 2017 | 28653102 |
| in vitro studies of nanosilver-doped titanium implants for oral and maxillofacial surgery. | the addition of an antibacterial agent to dental implants may provide the opportunity to decrease the percentage of implant failures due to peri-implantitis. for this purpose, in this study, the potential efficacy of nanosilver-doped titanium biomaterials was determined. titanium disks were incorporated with silver nanoparticles over different time periods by tollens reaction, which is considered to be an eco-friendly, cheap, and easy-to-perform method. the surface roughness, wettability, and si ... | 2017 | 28652733 |
| efficacy of antibiotic treatment of implant-associated staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study. | the efficacy of antibiotic monotherapy and combination therapy in the treatment of implant-associated infection by staphylococcus aureus was evaluated in an animal study. the femoral medullary cavity of 66 male wistar rats was contaminated with s. aureus (atcc 29213) and a metal device was implanted, of which 61 could be evaluated. six treatment groups were studied: flucloxacillin, flucloxacillin in combination with rifampin, moxifloxacin, moxifloxacin in combination with rifampin, rifampin, and ... | 2017 | 28652709 |
| properties of induced antimicrobial activity in musca domestica larvae. | insects produce antimicrobial molecules that contribute to their innate immune responses to eliminate invading microorganisms. to explore the potential utility of these antimicrobial molecules, we focused on larvae of the house fly musca domestica, which is an efficient processor of organic waste and a good resource of protein and oil for animal feeding. the induction of hemagglutinating activity, which is usually accompanied by activation of innate immune responses in fly larvae, was observed i ... | 2017 | 28652511 |
| advances in atopic dermatitis and urticarial in 2016. | this review highlights recent key advances in the pathology and therapies of inflammatory skin diseases, focusing on atopic dermatitis (ad) and chronic spontaneous urticaria (csu). regarding ad, transcriptomic analysis with human samples revealed different immune profiles between childhood and adult ad. phase iii clinical trials of dupilumab, an anti-il-4 receptor α antibody, in the treatment of ad have successfully finished, and dupilumab will appear in clinical practice as the first biologic f ... | 2017 | 28652155 |
| anti-inflammatory effect of man-pen-fang, a chinese herbal compound, on chronic pelvic inflammation in rats. | traditional chinese medicine (tcm) has become the focus of research for the treatment of chronic pelvic inflammatory disease (cpid) based on unique medical theory system. man-pen-fang (mpf), a chinese herbal compound, which is composed of thlaspi arvense l. (cruciferae), gleditsia sinensis lam. (leguminosae), smilax china l. (liliaceae), euonymus alatus (thunb.) sieb. (celastraceae) and vaccaria segetalis (neck.) (caryophyllaceae) mpf has been used for the treatment of cpid and exerted significa ... | 2017 | 28652014 |
| septic arthritis following arthroscopic reconstruction of cruciate ligaments of the knee: retrospective case review. | rupture of cruciate ligaments of the knee is a common injury that is repaired by arthroscopic reconstruction, which can give rise to septic arthritis. the objective of this article is to describe the clinical and microbiological aspects of this entity. | 2017 | 28651785 |
| characterization of phytoconstituents and evaluation of antimicrobial activity of silver-extract nanoparticles synthesized from momordica charantia fruit extract. | our present study was conducted to characterize the phytoconstituents present in the aqueous extract of momordica charantia and evaluate the antimicrobial efficacy of silver-extract nanoparticles (ag-extract-nps). | 2017 | 28651578 |
| inactivation of pathogenic microorganisms in freshwater using hso5(-)/uv-a led and hso5(-)/m(n+)/uv-a led oxidation processes. | freshwater disinfection using photolytic and catalytic activation of peroxymonosulphate (pms) through pms/uv-a led and pms/m(n+)/uv-a led [m(n+) = fe(2+) or co(2+)] processes was evaluated through the inactivation of three different bacteria: escherichia coli (gram-negative), bacillus mycoides (sporulated gram-positive), staphylococcus aureus (non-sporulated gram-positive), and the fungus candida albicans. photolytic and catalytic activation of pms were effective in the total inactivation of the ... | 2017 | 28651081 |
| treatment approach for infection of healed fractures after internal fixation. | to review the efficacy of a treatment approach for patients with infection and colonized implants after open reduction and internal fixation of fractures. | 2017 | 28650945 |
| healthy bovines as reservoirs of major pathogenic lineages of staphylococcus aureus in portugal. | the nosocomial prevalence of methicillin-resistant staphylococcus aureus (mrsa) in portugal is close to 50% and remains one of the highest in europe. mrsa reservoirs in the animal setting in portugal have been very poorly investigated, namely among animal husbandry. a total of 52 samples (nasal, inguinal region, and milk) were obtained from bovine animals and analyzed for the presence of s. aureus. the isolates were characterized by pulsed-field gel electrophoresis (pfge), spa typing, sccmec typ ... | 2017 | 28650693 |