Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| comparative anatomical distribution of 5-ht1a receptor mrna and 5-ht1a binding in rat brain--a combined in situ hybridisation/in vitro receptor autoradiographic study. | the present study examined the comparative distribution of 5-ht1a receptor mrna and 5-ht1a receptors in rat brain using a combination of in situ hybridisation histochemistry and in vitro receptor autoradiography. 5-ht1a mrna was visualized using a 910 bp crna probe synthesised from a bali-pvuii fragment of the rat 5-ht1a reetor gene, while 5-ht1a receptors were labelled with the 5-ht1a-selective ligand 8-oh-dpat. in general terms, there was a complementary distribution of cells expressing 5-ht1a ... | 1991 | 1797349 |
| comparative anatomical distribution of 5-ht1a receptor mrna and 5-ht1a binding in rat brain--a combined in situ hybridisation/in vitro receptor autoradiographic study. | the present study examined the comparative distribution of 5-ht1a receptor mrna and 5-ht1a receptors in rat brain using a combination of in situ hybridisation histochemistry and in vitro receptor autoradiography. 5-ht1a mrna was visualized using a 910 bp crna probe synthesised from a bali-pvuii fragment of the rat 5-ht1a reetor gene, while 5-ht1a receptors were labelled with the 5-ht1a-selective ligand 8-oh-dpat. in general terms, there was a complementary distribution of cells expressing 5-ht1a ... | 1991 | 1797349 |
| intravenous hypertonic saline induces fos immunoreactivity in neurons throughout the lamina terminalis. | expression of fos, the protein product of c-fos, was studied immunohistochemically in the forebrain of rats infused intravenously with hypertonic solutions. intravenous 1.5 or 0.75 mol/l nacl or 1.2 mol/l sucrose in 0.15 mol/l nacl, but not isotonic 0.15 mol/l nacl, caused increased fos expression in the hypothalamic paraventricular and supraoptic nuclei and throughout the lamina terminalis (organum vasculosum laminae terminalis, median preoptic nucleus and subfornical organ). these results show ... | 1991 | 1797341 |
| intravenous hypertonic saline induces fos immunoreactivity in neurons throughout the lamina terminalis. | expression of fos, the protein product of c-fos, was studied immunohistochemically in the forebrain of rats infused intravenously with hypertonic solutions. intravenous 1.5 or 0.75 mol/l nacl or 1.2 mol/l sucrose in 0.15 mol/l nacl, but not isotonic 0.15 mol/l nacl, caused increased fos expression in the hypothalamic paraventricular and supraoptic nuclei and throughout the lamina terminalis (organum vasculosum laminae terminalis, median preoptic nucleus and subfornical organ). these results show ... | 1991 | 1797341 |
| effects of the glycine prodrug milacemide (2-n-pentylaminoacetamide) on catecholamine secretion from isolated adrenal medulla chromaffin cells. | 1. milacemide (2-n-pentylaminoacetamide) is a glycine prodrug which readily crosses the blood brain barrier and increases brain glycine and glycineamide. in vitro and in vivo studies, with numerous tissues, including adrenal chromaffin cells, have clearly shown that the formation of the latter metabolites is exclusively mediated by monoamine oxidase b for which milacemide is a substrate. 2. milacemide, glycineamide and glycine caused a time- and dose-dependent release of catecholamines from bovi ... | 1991 | 1797336 |
| effects of the glycine prodrug milacemide (2-n-pentylaminoacetamide) on catecholamine secretion from isolated adrenal medulla chromaffin cells. | 1. milacemide (2-n-pentylaminoacetamide) is a glycine prodrug which readily crosses the blood brain barrier and increases brain glycine and glycineamide. in vitro and in vivo studies, with numerous tissues, including adrenal chromaffin cells, have clearly shown that the formation of the latter metabolites is exclusively mediated by monoamine oxidase b for which milacemide is a substrate. 2. milacemide, glycineamide and glycine caused a time- and dose-dependent release of catecholamines from bovi ... | 1991 | 1797336 |
| endotoxin induces eosinophil accumulation in the rat pleural cavity. | changes in eosinophil counts after intrathoracic (it) injection of endotoxin (lps) were investigated in wistar rats (150-180 g). increasing doses of endotoxin (62.5-500 ng/cavity) induced a dose-dependent increase in the number of eosinophils recovered from the rat pleural cavity 24 h later. the eosinophilia was apparent within 24 h, peaked within 48 h (from 0.76 +/- 0.12 to 3.68 +/- 0.51 eosinophils x 10(6)/cavity, p less than 0.001) and returned to basal levels 120 h after the it injection of ... | 1991 | 1797292 |
| endotoxin induces eosinophil accumulation in the rat pleural cavity. | changes in eosinophil counts after intrathoracic (it) injection of endotoxin (lps) were investigated in wistar rats (150-180 g). increasing doses of endotoxin (62.5-500 ng/cavity) induced a dose-dependent increase in the number of eosinophils recovered from the rat pleural cavity 24 h later. the eosinophilia was apparent within 24 h, peaked within 48 h (from 0.76 +/- 0.12 to 3.68 +/- 0.51 eosinophils x 10(6)/cavity, p less than 0.001) and returned to basal levels 120 h after the it injection of ... | 1991 | 1797292 |
| bacteriocin-mediated inhibition of clostridium botulinum spores by lactic acid bacteria at refrigeration and abuse temperatures. | the bacteriocinogenicity of lactococcus lactis atcc 11454, pediococcus pentosaceus atcc 43200, p. pentosaceus atcc 43201, lactobacillus plantarum bn, l. plantarum lb592, l. plantarum lb75, and lactobacillus acidophilus n2 against clostridium botulinum spores at 4, 10, 15, and 35 degrees c was investigated by modified deferred and simultaneous antagonism methods. all the strains, except l. acidophilus n2, produced inhibition zones on lawns of c. botulinum spores at 30 degrees c. l. plantarum bn, ... | 1991 | 1785919 |
| recovery of vancomycin-resistant gram-positive cocci from pediatric liver transplant recipients. | between november 1988 and october 1989, 49 first-time pediatric liver transplant recipients at the children's hospital of pittsburgh were prospectively monitored for the presence of stool colonization and the development of disease caused by vancomycin-resistant gram-positive cocci (vrgpc). quantitative stool culturing was done on a weekly basis, and cultures were planted onto a selective medium for vrgpc. isolates for which the mic was greater than or equal to 8 were considered resistant to van ... | 1991 | 1774255 |
| septicaemia caused by pediococcus pentosaceus: a new opportunistic pathogen. | a case of septicaemia caused by pediococcus pentosaceus is described. the role played by pediococci, and other vancomycin-resistant gram-positive cocci, in disease states is examined. we suggest that in immunocompromised patients these organisms act as opportunist pathogens. this would appear to be the first reported case of p. pentosaceus septicaemia. | 1991 | 1753117 |
| conduction velocity distribution of afferent fibers innervating the rat urinary bladder. | the conduction velocities of individual afferent fibers innervating the rat urinary bladder were determined by the antidromic stimulation of dorsal roots while recording from bladder postganglionic nerves. conduction velocities ranged from 0.5 to 21.0 m/s; 70% of the velocities were less than 2.5 m/s. the distribution within the dorsal roots was ipsilateral with 84% in l6 and 16% in s1. neuroanatomical tracing with horseradish peroxidase applied to individual bladder postganglionic nerves result ... | 1990 | 1698508 |
| treatment of multiple intracranial aneurysms in the anterior circulation--case report. | a 69-year-old female underwent surgery for subarachnoid hemorrhage due to a ruptured intracranial aneurysm. nine additional aneurysms were found. four of the latter nine aneurysms were clipped in a second operation, and two were wrapped. | 2006 | 1694273 |
| spatial and temporal regulations in helicoidal extracellular matrices: comparison between plant and animal systems. | this paper proposes an overview of the last few years' investigations regarding the helicoid formation in extracellular matrices (ecms). despite the architectural polymorphism displayed among the layered ecm throughout the living kingdom, helicoidal structures are often described in ecms and appear as an optimal mechanical device. helicoids correspond to complex two-phases composites, formation and regulation of which are still a source of debate. taking the time-event into consideration, it is ... | 2006 | 1636171 |
| soft tissue sarcomas: experience with intraoperative brachytherapy in the conservative management. | forty-eight patients with soft tissue sarcomas were treated with iridium implant after wide local excision between 1980 and 1990 at our institution. external irradiation was also given postoperatively in 33 patients with initially resectable tumours (treatment a) and preoperatively in 3 with initially unresectable tumours (treatment c); brachytherapy was the only treatment in 12 patients presenting small superficial tumours or recurring after previous irradiation (treatment b). median follow up ... | 2006 | 1622870 |
| headspace flavour compounds produced by yeasts and lactobacilli during fermentation of preferments and bread doughs. | production of volatile flavour compounds during fermentation with pure cultures of saccharomyces cerevisiae and candida guilliermondii, lactobacillus brevis and lactobacillus plantarum have been investigated, using wheat doughs and several preferements as substrates. for yeast, preferments consisted of 10% (w/v) glucose, maltose and sucrose solutions, whereas for lactobacilli they consisted of supplemented and unsupplemented (3% and 10% (w/v)) glucose solutions, and a 10% (w/v) wheat flour slurr ... | 1992 | 1622751 |
| pharmacokinetic interaction between 1,3-butadiene and styrene in sprague-dawley rats. | gas uptake studies were carried out to evaluate kinetic interactions between 1,3-butadiene and styrene in sprague-dawley rats. the animals were co-exposed by inhalation to a mixture of 1,3-butadiene between 20 and 6000 ppm (v/v) and styrene between 0 and 500 ppm. the data demonstrate that metabolism of 1,3-butadiene was partially inhibited by styrene. the inhibition was competitive at atmospheric concentrations of styrene up to 90 ppm. higher concentrations of styrene resulted in a small additio ... | 1992 | 1610292 |
| occurrence of antinuclear antibodies in an unselected pregnancy population. | the occurrence of antinuclear antibodies (ana) in an unselected population of pregnant women was studied by an indirect immunofluorescence method. six women out of 116 were ana-positive (5.2%), 2 of them having a moderately high titre (1:160 and 1:320) and 1 complement-fixing ana. the antigenic specificity of ana was anti-single-stranded dna in 2 cases and rnaase-sensitive anti-extractable nuclear antigen in 1 case. two of the ana-positive women had pre-eclampsia laevis and 1 had a premature del ... | 2006 | 1563653 |
| external cephalic version and daily post-versional maternal self-assessment of fetal presentation. a prospective study. | external cephalic version (ecv) using tocolysis is a widely recognized low-risk intervention in cases of breech presentation, particularly in areas where resources are scarce and the perinatal mortality is high in vaginal breech deliveries. in such a setting, pregnant women were trained to make regular self-assessments of the presenting fetal part after ecv in order to detect spontaneous reversions to breech presentation. it was found that such maternal involvement could significantly improve th ... | 2006 | 1563651 |
| intrauterine resuscitation in the severely distressed fetal dog. | severe fetal distress was produced in 16 fetal dogs by successive and/or prolonged occlusion of the maternal abdominal aorta in an acute surgical preparation, and was characterized in fetal arterial blood of 7.06 for ph, 10 mm hg for o2, 127 mm hg for co2, and fetal heart rate decelerations. five fetuses recovered spontaneously in utero and delivered normally; 3 needed maternal oxygenation before delivery; 3 suddenly died in utero; 5 fetuses were delivered while still alive in utero when the tph ... | 1992 | 1563650 |
| medical waste: science vs politics. | 2006 | 1539964 | |
| cd45 isoform expression on human neonatal t cells: expression and turnover of cd45 isoforms on neonatal versus adult t cells after activation. | neonatal t cells are phenotypically similar to "naive" t cells from adult donors in the cd45 isoform expression. despite the phenotypic similarity, large differences were found between neonatal and adult t cells when t cells were activated. after activation with pha, adult cd45ra+ t cells began to express cd45ro and no loss of cd45ra expression had yet occurred at day 3 post-stimulation. three days after activation, cd45ra+ neonatal t cells also coexpressed cd45ro; however, in contrast to adult ... | 1992 | 1534035 |
| the effects of na(+)-k(+)-cl- co-transport and cl(-)-hco3-exchange blockade on the membrane potential and intracellular chloride levels of rat arterial smooth muscle, in vitro. | membrane potential and intracellular chloride levels have been measured simultaneously in vascular smooth muscle from the femoral artery of the rat, in vitro, using double-barrelled chloride-sensitive microelectrodes. these values are compared in the presence and absence of bicarbonate, and inhibitors of cl(-)-hco3- exchange and na(+)-k(+)-cl- co-transport. both dids and bumetanide caused a hyperpolarization of membrane potential (em) and a fall in [cl-]i, in the presence of extracellular hco3-. ... | 1992 | 1489543 |
| the scope of professional practice. | 2006 | 1483017 | |
| capture, mutate, quantitate: variations of a central pcr scheme. | 2006 | 1472383 | |
| transforming growth factor beta and basic fibroblast growth factor synergistically promote early bovine embryo development during the fourth cell cycle. | developmentally competent bovine blastocysts were produced by adding transforming growth factor beta (tgf beta) and basic fibroblast growth factor (bfgf) to serum-free cultures of in vitro produced, 2-cell bovine embryos. the effects of tgf beta were evaluated because this growth factor signals synthesis and secretion of the extracellular matrix component fibronectin and its receptor. previous investigations have demonstrated that fibronectin promotes early bovine embryo development in vitro. th ... | 1992 | 1472373 |
| pyomyositis and cryptococcal sepsis in an hiv-infected patient with severe granulocyte defect. | 1992 | 1472345 | |
| [the comprehensive diagnosis and treatment of lymphosarcoma of the pharynx]. | modern methods (intrascopic and other instrumental) were used to increase the diagnostic efficiency and extension of the tumour process in 22 patients with lymphosarcoma of the pharynx. optimal treatment efficacy is achieved in lymphosarcoma of the pharynx by combined use of surgical, radiation (non-traditional course) treatment as well as chemotherapy which is used at early stages as an adjunctive method. | 2006 | 1448998 |
| unilateral headache with features of hemicrania continua and cervicogenic headache--a case report. | a case is presented which has features of cervicogenic headache and of hemicrania continua. a sudden maneuver of the neck and later a greater occipital nerve block, both resulted in relief of the pain. a cervical cause is suggested. | 2006 | 1446991 |
| effects of magnesium on cocaine-reinforced responding in mice, rats and squirrel monkeys. | 1992 | 1435977 | |
| promoting sexual health. | 2006 | 1392896 | |
| inhibition of trypsin by t-butyloxycarbonyl-alpha-aza-(4-aminophenyl)alanine phenyl ester. | t-butyloxycarbonyl-alpha-aza-(4-aminophenyl)alanine phenyl ester (iii: r = nh2) has been synthesized. the rate of inhibition of trypsin (ec 3.4.21.4) by this compound (due to acylation followed by slower deacylation) shows a marked ph maximum at approximately 6. the shape of the ph-rate curve is discussed in terms of (i) the normal ph-activity curve of trypsin reacting with a charged substrate, i.e. the protonated form of the amino compound, (ii) the deprotonation of the 4-amino group with pka 4 ... | 2006 | 1367228 |
| reaction mechanism of glutamate racemase, a pyridoxal phosphate-independent amino acid racemase. | glutamate racemase of pediococcus pentosaceus contained no cofactor, and was completely inactivated by a thiol reagent. the role of a cysteine residue in the enzyme reaction was studied by chemical modification. the modification of this cysteine residue resulted in a concomitant loss of activity. dl-glutamate protected the enzyme from inactivation. the inactivated enzyme was reactivated by addition of dithiothreitol. the racemization in 2h2o showed an overshoot in the optical rotation of glutama ... | 1992 | 1358877 |
| [molecular bases of chronic granulomatous disease--analysis of the involvement of cytosol factors for nadph oxidase]. | during the past 5 years, the discovery of cell-free superoxide generation system (bromberg y, pick e: cell immunol 88:213-221, 1984) has been revolutionized our understanding of phagocyte superoxide generation. using cell-free system, it was clarified that nadph oxidase for superoxide generation was comprised of components present in both the plasma membrane as well as in the cytosol. this oxidase could be kept inactive by keeping its components separated from each other within the cell and then ... | 2005 | 1317471 |
| concentrations of endothelial-cell-stimulating angiogenesis factor, a major component of human uterine angiogenesis factor, in human and bovine embryonic tissues and decidua. | embryonic development involves the establishment of new patterns of vascular growth in the fetus and within the lining of the womb. a factor, human uterine angiogenesis factor, has been purified from the decidua and stimulates the growth of blood vessels in collagen sponge implants and in the chick chorioallantoic membrane. evidence is presented that suggests that a major active component of human uterine angiogenesis factor is an activator of latent matrix metalloproteinases, of low m(r), calle ... | 1992 | 1317450 |
| on the mechanism of action of picrotoxin on gaba receptor channels in dissociated sympathetic neurones of the rat. | 1. the mechanism of action of picrotoxin on gaba receptor channels in rat sympathetic neurones has been investigated with whole-cell clamp. in addition, the action of picrotoxin on single gaba channels has been examined in outside-out membrane patches from these cells. 2. picrotoxin, at concentrations which dramatically reduced the amplitude of whole-cell gaba currents, did not alter the spectral time constants or single-channel conductance estimated by analysis of gaba-activated current noise. ... | 1992 | 1317428 |
| tert-butyl hydroperoxide-induced radical production in rat liver mitochondria. | when rat liver mitochondria are treated with tert-butyl hydroperoxide (tbhp) in the presence of the spin trap 5,5-dimethyl-1-pyrroline n-oxide (dmpo), electron paramagnetic resonance (epr) signals are detected attributable to spin adducts resulting from the trapping of methyl, tert-butoxyl, and tert-butylperoxyl radicals. the addition of respiratory substrate results in a 3- to 7.5-fold increase in the signal intensity of the dmpo/methyl adduct, no change in the signal intensity of the dmpo/tert ... | 1992 | 1317326 |
| use of adeno-associated virus as a general transduction vector for mammalian cells. | 1992 | 1316261 | |
| epidemiologic observations on suicides in virginia. | 2005 | 1266370 | |
| linkage studies between hl-a and gpt polymorphisms and other genetic markers. | the phenotypes of 56 families with 126 children from the hamburg area as well as gene frequencies and segregation of the genetic markers gpt, ap, ada, ak, pgm1, pgm3, 6-pgd, che, c3, gc, tf, hp and cp were studied. in regard to linkage, the informative families were correlated to the results of hl-a and gpt typing. the linkage was tested according to the sequential test by morton (1955). see article. for other gene loci, linkage to the hl-a or gpt system could not be proved. but the positive lod ... | 2005 | 1251571 |
| a 2-year follow-up of 72 hyperactive boys. classroom behavior and peer acceptance. | a 2-year, prospective follow-up of 72 hyperactive boys (94 per cent of the initial sample) examined classroom and home behavior, academic achievement, peer status, and depressive symptomatology for patients and a matched control group. sixty-five per cent of the sample was still on medication at follow-up. the patient group continued to manifest behavioral and academic difficulty. off-drug classroom behavior showed considerable stability from baseline to 2-year follow-up which did not appear to ... | 2005 | 1249566 |
| management of pathological fractures at the mayo clinic. | 2005 | 1234120 | |
| effects of subzero temperatures on the microcirculation in the oral mucous membrane. | 2005 | 1214600 | |
| a volumetric assessment of pollen levels in the air of ann arbor, michigan. | 2005 | 1196148 | |
| [thrombotic occlusion and late lysis in the arteria subclavia lusoria dextra]. | case history of a 45 years aged male patient with an aortic arch anomaly. thrombotic occlusion of the a. lusoria dextra with symptoms of a subclavian-steal syndrome and anoxia in the right hand. spontaneous lysis after 8 weeks is documentated by arteriography. | 2005 | 1183296 |
| thoughts about medical writing. xxix. authorship-who, and where? | 2005 | 1169027 | |
| [massive lower gastrointestinal hemorrhage of diverticular origin. diagnostic and therapeutic problems]. | 2005 | 1082809 | |
| transplantation behavior of a.th and a.tl t-cell lymphomas in congenic resistant and hybrid strains. | seven spontaneously arising t-cell lymphomas originating in a.th or a.tl mice, which are congenic for the immune response gene (i) chromosomal segment were described. when transplanted into partner strains which were incompatible at the i region, the tumors were rapidly rejected. rejection was proposed to be due to the presence of antigens controlled by i-region genes. | 2005 | 1079852 |
| [the total suppression of the external pancreatic secretion of the dog (author's transl)]. | 1979 | 544203 | |
| effects of ca+ and k+ on oscillatory afterpotentials in dog ventricular muscle fibers. | 1979 | 522140 | |
| the need for health care--a pilot survey with general practice. | a feasibility study was carried out in two places in wiltshire of a method of ascertaining the morbidity of the population. traditional medical history taking and examination of the individuals were completed in a random sample of the population, of whom 89 per cent were contacted. the method appears feasible for a survey of sufficient size to measure morbidity and the study gave useful preliminary indications of unmet health care need. the cost of such a larger survey would be small in relation ... | 2004 | 522069 |
| a study of repeat prescription cards in a general practice. | a study of repeat prescription cards in a general practice revealed problems in good record keeping and patient recall. a system involving a repeat register was therefore developed to create an easily accessible practice record and a recall procedure was initiated. greater control over repeat cards is now possible.examination of the age and sex of the card-holders showed a high proportion of elderly females. by scrutiny of the contents of the cards, a profile of prescribing in the practice was d ... | 2004 | 522065 |
| external factors influencing blood gas analysis: quality control revisited. | 2004 | 517557 | |
| the lipid composition of rat brain aggregating cell cultures during development. | the lipid and fatty acid composition of rat brain was studied during its development both in vivo and in an aggregating cell culture system. although the amount of lipid present in the cultures was very low, the increase in glycolipid content corresponded closely to the period of intense myelin formation. very long chain fatty acids (hydroxylated and unsubstituted) were present in 41-day cultures. in comparison to the in vivo situation, myelination was delayed in vitro and, after 40 days in cult ... | 1979 | 514541 |
| lung biopsy in sarcoidosis. | 2004 | 421597 | |
| the myelodysplasia and hydrocephalus program in nebraska: a 15 year review of costs and benefits. | 2004 | 412114 | |
| application of laser raman and infrared spectroscopy to the analysis of membrane structure. | 2004 | 383152 | |
| clifford d. evans. | 2004 | 383130 | |
| aortic valve replacement in a case of ehlers danlos syndrome. | a case of ehlers danlos syndrome is described in a 54-year-old caucasian male. he had calcific aortic valve disease and dilatation of the ascending aorta. an aortic valve replacement was performed using a starr prosthesis. | 2004 | 383121 |
| legionnaires' disease. a cause of lung abscess. | 2004 | 368366 | |
| [eosinophilic leukosis]. | 2003 | 290268 | |
| [fractures of the temporomandibular joint extension in growth years]. | 1963 | 278340 | |
| insulin resistance due to a defect distal to the insulin receptor: demonstration in a patient with leprechaunism. | we have studied a 2-year-old girl with acanthosis nigricans, glucose intolerance, marked hyperinsulinemia, and somatic features characteristic of the leprechaunism syndrome. circulating plasma insulin levels were increased up to 50-fold and the patient showed a blunted hypoglycemic response to an injection of exogenous insulin (0.2 units/kg), indicating the presence of severe insulin resistance. insulin purified from the patient's plasma was normal on the basis of chromatographic, electrophoreti ... | 1978 | 277948 |
| coercive treatment for alcoholic 'driving under the influence of liquor' offenders. | 1991 | 270362 | |
| a case of gastric leiomyoblastoma with metastasis to the liver. | 2003 | 262300 | |
| [thyroid ectopy. growth retardation]. | 2003 | 262258 | |
| isoelectric focusing of proteins using a ph gradient created by a concentration gradient of nonelectrolytes in solution. | a new method of producing a stable ph gradient in buffer solutions is suggested, obtained by the concentration gradient of a nonelectrolyte in buffer solutions as a result of the gradual change in the dielectric properties of the solution. the maximal concentrations of nonelectrolyte which do not influence the protein configuration allow a ph gradient with a range of two ph units to be produced. it is suggested that the properties of some polyols (i.e. glycerol or mannitol) be used to change the ... | 1975 | 238655 |
| common mesophilic anaerobes, including clostridium botulinum and clostridium tetani, in 21 soil specimens. | a relatively rich medium was markedly superior to a dilute medium for the isolation of anaerobic bacteria from soil. the obligate anaerobes isolated from 21 soil samples were all clostridia and the counts ranged from 2.7 x 10-2 to 3.3 x 10-6 per g. the organisms most frequently isolated were clostridium subterminate, c. sordelii, c. sporogenes, c. indolis, c. bifermentans, c. mangenoti, and c. perfringens. seventeen other species were also recognized but almost one-third of the isolates could no ... | 1975 | 238468 |
| characterization of a unique cell line (laz 221) from human acute lymphocytic ("null" cell) leukemia. | a unique human cell line designated laz 221 has been established from the peripheral blood of a patient with acute lymphocytic leukemia of the "null" cell type. the cell line does not possess the epstein-barr virus nuclear antigen and has a karyotype of 45,xx,-9,-12,+(9q12q). both the established cell line and the patient's uncultured blast cells share the same phenotypic markers. they both lack t-cell markers. they fail to form sheep erythrocyte rosettes and do not react with t-cell-specific an ... | 1978 | 205365 |
| cell membrane structure of human giant-celled glioblastoma. | a giant-cell glioblastoma was examined by electron microscopy and by the freeze-fracture technique. the cell membranes bordering the extensive extracellular space often showed complicated undulations and peripheral vacuoles as well as occasional microvilli or filopodia. the undulations were mainly composed of plasmalemmal vesicles as well as of large (400--800 nm in diameter) and small (30--50 nm in diameter) localized protrusions and invaginations of the cell membrane. deep invaginations of the ... | 1978 | 205080 |
| distribution of corticotrophin releasing factor activity within the hypothalamic-pituitary complex of rats and cattle. | an assay system involving cultured rat adenohypophysial cells from either intact or adrenalectomized donors was used to study the distribution of corticotrophin releasing factor (crf) activity in the hypothalamic-pituitary complex of rats and cattle. in the rat hypothalamus, crf activity was most concentrated in the median eminence, but crf was present in the stalk and the posterior pituitary gland in much higher concentrations than in the median eminence in both species. the dose--response slop ... | 1977 | 201710 |
| the equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver. | the reversibility of the nad+ kinase reaction was established, and the kinetic parameters of the rate equation in the reverse direction were determined. the equilibrium constant of the reaction was determined by using the purified pigeon liver enzyme and radioactively labelled nicotinamide nucleotides. the relationship between kinetic parameters of the forward and reverse reactions is in reasonable agreement with the measured equilibrium constant. as expected from the proposed mechanism of actio ... | 2003 | 201249 |
| herpesvirus-induced urolithiasis in specific-pathogen-free male cats. | 1977 | 201200 | |
| actions and interactions of theophylline and imidazole on cardiac contractility, phosphorylase activation and cyclic amp. | injection of 1.0 mg theophylline and 1.6 mg imidazole into guinea-pig hearts perfused by the langendorff technique increased cardiac contractile force by 20.0 +/- 1.0% and 23.3 +/- 1.2% over control and activated phosphorylase without producing significant changes in cyclic amp levels. when guinea-pig hearts were perfused with theophylline (10(-3) m) or imidazole (20 mm), injection of either imidazole or theophylline did not further increase cardiac contractility or phosphorylase a levels. in al ... | 1976 | 183614 |
| [cyclic amp. biochemical and clinical aspects]. | 2003 | 166470 | |
| [relation between endocrinology and psychiatry. some recent developments]. | relations between endocrinology and psychiatry are developing in two main directions: behavioural effects of hormones. after the effects of peripheral hormones, recent works are concerned with a.c.t.h. and antidiuretic hormone (which interfere with memory process) and with hypothalamic peptides (which might have psychotropic properties, independant of their endocrine regulation function). -correlations between psychiatric syndroms and endocrine disorders. in some mentally depressed patients, dis ... | 2003 | 165466 |
| deoxyribinucleic acid-binding proteins in virus-transformed cell lines. | the synthesis of proteins with affinity for dna has been studied in clones of a syrian hamster cell line (nil) and subclones of this line transformed by polyoma virus (nil-py) or hamster sarcoma virus (nil-hsv). the results show that the synthesis of dna-binding proteins in nil and in its virus-transformed derivatives nil-py and nil-hsv is very similar in exponentially growing cells, but in dense culture there is a very significant difference in the level of a protein (p8), which is much higher ... | 1975 | 165180 |
| effect of a mild exercise program on myocardial function and the development of hypertrophy. | cardiac function and the development of myocardial hypertrophy were studied in rats conditioned by an exercise program consisting of 8 wk of running on a treadmill. at the end of the training period a group of exercised and sedentary rats was subjected to hemodynamic evaluation under general anesthesia. except for a slight elevation in the heart rates of the exercised animals there were no significant differences between the exercised and sedentary rats at rest. following an increase in afterloa ... | 1979 | 154493 |
| satellite association in human metaphases. a comparative study of normal individuals, patients with down syndrome and their parents. | 1979 | 154489 | |
| synthetic arterial grafts. iii. the outcome in 22 patients with synthetic axillofemoral bypass grafts. | during the 4-year period 1973--76, 22 patients were operated upon with axillofemoral bypass grafts at the department of surgery in lund. they were high-risk patients with severe ischaemia of the leg or previous graft infections. fourteen of the 22 grafts were well-functioning after the longest observation time of 32 months. the operative procedure is described and postoperative compliations are reviewed. the axillofemoral bypass reconstruction is recommended as an alternative for this category o ... | 2003 | 152457 |
| functional differences of ouabain and ethacrynic acid on renal potassium metabolism in dogs. | current concepts provide inadequate explanations for the effects of ethacrynic acid (eca) and ouabain (oua) on renal potassium metabolism because neither the site of action, nor the tubular effects have been agrreed upon. in the present study on anaesthetized dogs, in vivo inhibitory effects of eca on mitochondria or na-k-atpase were excluded. firstly, eca hardly reduced outer medullary metabolic rates in kidneys exposed to oua and 2,4-dinitrophenol. secondly, whereas oua reduced renal na-katpa ... | 1978 | 152453 |
| assessing the physically disabled: social factors in rehousing. | 2003 | 152442 | |
| [diagnostic problems of primary amyloidosis]. | surgical liver biopsy specimen of a women aged 58 with "biliary complaints" showed amyloid deposits of unknown nature. after a nearly two-years-course of the disease the patient died of cardiac and renal failure. clinical findings and laboratory tests without abnormal serum globulins suggested primary amyloidosis. morphologically amyloid was present in the heart, tongue, striated muscles and in many parenchymatous organs and endocrine glands. by electron microscopy no difference was revealed bet ... | 2003 | 152408 |
| unrestricted donations are capital funds, not revenue. | 2003 | 152389 | |
| [state of dental health of a group of handicapped adult in jönköping]. | 2003 | 150056 | |
| hodgkin's disease in children. | 2003 | 149946 | |
| [j. a. comenius' magia et scientia]. | 2002 | 135380 | |
| [menetrier's disease: protein-losing gastropathy and antiplasmin therapy (author's transl)]. | 2002 | 135109 | |
| [chemotherapy of swine dysentery]. | 1975 | 129937 | |
| [importance of hygiene in the prevention of infectious atrophic rhinitis]. | 1975 | 129905 | |
| spasticity: actions of selectivity activated group ii muscle spindle afferents on extensor motoneurons. | 1975 | 129880 | |
| staphylococcal micrococcins. i. isolation of antibiotic-producing strains. | seven strains belonging to the family micrococcaceae and possessing strong antagonistic properties against staph. aureus and several other gram-positive bacteria, have been isolated. the strains were characterized and identified, phage typed, tested for antibiotic-sensitivity and antagonistic activities. two patients of inhibition were noted. | 1975 | 126688 |
| [histochemical changes in the morphologic structure of tissues in women with inflammatory diseases of the internal genital organs]. | 2002 | 124045 | |
| the radiographic diagnosis of heart disease in the dog. | 1975 | 123974 | |
| the diagnosis of genitourinary neoplasms. | 2002 | 123911 | |
| [quantitative changes in the cellular makeup of the spleen in mice infected with the rauscher leukemia virus and brucella abortus]. | changes in the absolute number of splenic cells of mice infected with rauscher leukemia virus (rlv) and a day later--with living brucella (ba) were studied. the increase in the absolute number of splenic cells of mice infected with rlv + ba was initially caused by the lymphoid tissue reaction to brycella and then by the development of leukemia. the number of reticular cells in the spleen appeared to be larger than the control (rlv) within all observation periods; the number of basophilic normocy ... | 1979 | 111416 |
| [laboratory diagnosis of group d streptococcus]. | after taxonomic listing of group d streptococci, the authors discuss the methodology of the bacteriologic diagnosis of infections produced by these bacteria, showing the way in which the pathological products are collected, the strains isolated and seeded. the strains are identified in two stages: (1) group identification by group antigen identification, resistance to oxacillin, development at +45 degrees, development on bilaesculin media; (2) species and variety identification by biochemical, p ... | 1979 | 111334 |
| congenital hypothyroidism control programs. a cost-benefit analysis. | comprehensive screening programs to control congenital hypothyroidism (ch), a preventable form of mental retardation, are being considered by some public health agencies. the proposed programs would test neonates' blood for thyroxine and, if warranted, provide follow-up testing and therapy. the estimated cost of detecting a single case of ch is $9,300, which includes specimen collection, laboratory analysis, and retesting of border-line cases. the present value of the treatment costs of ch adds ... | 1998 | 108409 |
| [action for children]. | 1998 | 107435 | |
| primary structure of a human iga1 immunoglobulin. iv. streptococcal iga1 protease, digestion, fab and fc fragments, and the complete amino acid sequence of the alpha 1 heavy chain. | in order to establish the complete amino acid sequence of the human iga alpha1 chain bur, iga1 protease from streptococcus sanguis was employed to generate fabalpha and fcalpha fragments in the final stage of this investigation. cyanogen bromide cleavage of the fabalpha fragment followed by reduction and aminoethylation produced the fd' fragment (residues 84 to 227); this contains part of the variable region (vr), the whole first constant domain (calpha1), and part of the hinge region of this he ... | 1979 | 107164 |