Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| in vitro potency of doripenem tested against an international collection of rarely isolated bacterial pathogens. | doripenem, a new 1beta-methyl parenteral carbapenem, has very broad-spectrum activity against gram-positive and gram-negative aerobic bacteria. as noted here, the spectrum and potency extended to many rarely isolated species sampled by the doripenem global surveillance program. among the species or species groups with <or=0.14% prevalence (1959 strains tested), doripenem was active against 98.9% of enterobacteriaceae at <or=0.5 microg/ml. similarly, more than 90% of other rarely isolated gram-ne ... | 2009 | 19302927 |
| [primary bacteremias caused by pasteurella multocida]. | 2008 | 19296005 | |
| expression, purification and crystallization of class c acid phosphatases from francisella tularensis and pasteurella multocida. | class c nonspecific acid phosphatases are bacterial enzymes that are secreted across the cytoplasmic membrane and hydrolyze a variety of phosphomonoesters at acidic ph. these enzymes are of interest for the development of improved vaccines and clinical diagnostic methods. in one case, the category a pathogen francisella tularensis, the class c phosphatase plays a role in bacterial fitness. here, the cloning, expression, purification and crystallization methods for the class c acid phosphatases f ... | 2009 | 19255471 |
| identification of immunogenic proteins associated with protection against haemorrhagic septicaemia after vaccination of calves with a live-attenuated aroa derivative of pasteurella multocida b:2. | pasteurella multocida serotype b:2 is the causative agent of haemorrhagic septicaemia (hs), a fatal disease of cattle and buffaloes. as a step towards the identification of individual antigens that may protect against hs, proteins present in a sonicated cell extract (sce) and outer-membrane protein (omp) preparation of a wild-type p. multocida serotype b:2 were investigated by immunoblotting with sera from calves which had been protected against challenge with a virulent strain of p. multocida b ... | 2009 | 19243798 |
| [pasteurella multocida bacteremic meningitis]. | human infections by pasteurella multocida are usually associated with bites or scratches from dogs and cats. many of them are accompanied by other oropharyngeal microorganisms of these animals. we herein present a case of bacteremic meningitis by p. multocida in an 86-year-old woman who was living with seven cats. even though no skin or soft tissue infection was recorded, it is possible that a mild infection had gone undetected and a subsequent bacteremia had impacted on the meninges, or that me ... | 2008 | 19213242 |
| functions and regulatory mechanisms of gq-signaling pathways. | gq family members of heterotrimeric g protein activate beta isoforms of phospholipase c that hydrolyzes phosphatidylinositol phosphate to diacylglycerol and inositol trisphosphate, leading to the protein kinase c activation and intracellular ca(2+) mobilization, respectively. to understand the functions and regulatory mechanisms of gq-signaling pathways, we first introduce the galphaq-interacting proteins, which function as the effectors and the modulators of gq. next, we describe the pasteurell ... | 2009 | 19212139 |
| antimicrobial properties of the equine alpha-defensin defa1 against bacterial horse pathogens. | defensins are small effector molecules of the innate immune system, synthesised by various organisms including plants and animals. the peptides act as endogenous antibiotics with an antimicrobial activity against a broad spectrum of microbes including bacteria, fungi and viruses. alpha-defensins are a subgroup of the defensin family, their synthesis is limited to some tissues and furthermore to some mammalian species including the horse. equine defa1 is an enteric alpha-defensin exclusively prod ... | 2009 | 19211153 |
| neonatal pasteurellosis: a review of reported cases. | pasteurellosis is an uncommon infectious disease in humans mainly caused by pasteurella multocida infection in neonates and has been rarely reported. | 2009 | 19208671 |
| breast prosthesis infected by pasteurella multocida. | 2008 | 19186571 | |
| respiratory disease in calves: microbiological investigations on trans-tracheally aspirated bronchoalveolar fluid and acute phase protein response. | trans-tracheal aspirations from 56 apparently healthy calves and 34 calves with clinical signs of pneumonia were collected in six different herds during september and november 2002. the 90 samples were cultivated and investigated by pcr tests targeting the species histophilus somni, mannheimia haemolytica, pasteurella multocida, mycoplasma bovis, mycoplasma dispar, and mycoplasma bovirhinis. a pcr test amplifying the lktc-artj intergenic region was evaluated and shown to be specific for the two ... | 2009 | 19186010 |
| virulence of pasteurella multocida subsp. multocida isolated from outbreaks of fowl cholera in wild birds for domestic poultry and game birds. | chickens, turkeys, partridges and pheasants were experimentally infected with pasteurella multocida subsp. multocida to investigate whether outbreaks of fowl cholera in avifauna might represent a risk for organic, backyard and industrial poultry production. birds were infected intra-tracheally with a strain of p. multocida subsp. multocida (40605-1) isolated from outbreaks of fowl cholera in wild birds in denmark. p. multocida subsp. multocida strain p-1059 was included as a reference strain. th ... | 2001 | 19184870 |
| identification and typing of pasteurella multocida: a review. | pasteurella multocida is an important pathogen of many avian species. this review critically examines recent developments in new-generation tests for the identification and typing of this bacterium. two polymerase chain reaction (pcr) tests have been reported for p . multocida. both tests show promise as diagnostic tests that could be considered for routine use. however, there have not yet been effective evaluation studies that examine the ability of these new tests to distinguish between p. mul ... | 2000 | 19184816 |
| investigations on the carrier rate of pasteurella multocida in healthy commercial poultry flocks and flocks affected by fowl cholera. | twenty flocks of web-footed birds (pekin and muscovy ducks and geese) and eight flocks of chickens raised under intensive management were examined for the presence of carriers of pasteurella multocida. five hundred and seventy-eight web-footed birds and 240 chickens from healthy flocks, as well as from flocks affected by fowl cholera, were investigated. a total of 135 isolates (80 from healthy flocks and 55 from flocks affected by fowl cholera) were obtained from the pharyngeal and cloacal mucos ... | 2000 | 19184799 |
| identification of novel glycosyltransferases required for assembly of the pasteurella multocida a:1 lipopolysaccharide and their involvement in virulence. | we previously determined the structure of the pasteurella multocida heddleston type 1 lipopolysaccharide (lps) molecule and characterized some of the transferases essential for lps biosynthesis. we also showed that p. multocida strains expressing truncated lps display reduced virulence. here, we have identified all of the remaining glycosyltransferases required for synthesis of the oligosaccharide extension of the p. multocida heddleston type 1 lps, including a novel alpha-1,6 glucosyltransferas ... | 2009 | 19168738 |
| isolation, antimicrobial resistance, and virulence genes of pasteurella multocida strains from swine in china. | a total of 233 isolates of pasteurella multocida were obtained from 2,912 cases of clinical respiratory disease in pigs in china, giving an isolation rate of 8.0%. serogroup a p. multocida isolates were isolated from 92 cases (39.5%), and serogroup d isolates were isolated from 128 cases (54.9%); 12 isolates (5.2%) were untypeable. p. multocida was the fourth most frequent pathogenic bacterium recovered from the respiratory tract, after streptococcus suis, haemophilus parasuis, and escherichia c ... | 2009 | 19158260 |
| characterisation and comparison of avian pasteurella multocida strains by conventional and eric-pcr assays. | sixty-one avian strains of pasteurella multocida were characterised and compared by biochemical tests, capsular pcr typing and eric-pcr. the strains were recovered from various avian species (goose, duck, muscovy duck, turkey, chicken and pheasant) and represented different geographic locations in hungary. forty-two strains (69%) were identified as p. multocida subsp. multocida and 19 strains (31%) as p. multocida subsp. septica. the strains were grouped into 7 different biovars (1, 2, 3, 4, 5, ... | 2008 | 19149098 |
| host-pathogen interactions of actinobacillus pleuropneumoniae with porcine lung and tracheal epithelial cells. | host-pathogen interactions are of great importance in understanding the pathogenesis of infectious microorganisms. we developed in vitro models to study the host-pathogen interactions of porcine respiratory tract pathogens using two immortalized epithelial cell lines, namely, the newborn pig trachea (nptr) and st. jude porcine lung (sjpl) cell lines. we first studied the interactions of actinobacillus pleuropneumoniae, an important swine pathogen, using these models. under conditions where cytot ... | 2009 | 19139196 |
| recurrent infective endocarditis with uncommon gram-negative pasteurella multocida and pseudomonas aeruginosa: a case report. | infective endocarditis (ie) due to gram-negative bacteria is a rare occurrence, with a relative frequency of less than 10% compared to that caused by gram-positive bacteria. herein is presented the fatal case of a 66-year-old man who had undergone mechanical aortic valve replacement 10 years previously, and developed aortic valve ie after sepsis with pasteurella multocida caused by a cat bite at the left medial ankle. in addition, the patient suffered five months later from mitral and aortic val ... | 2008 | 19137805 |
| pasteurella multocida toxin activates gbetagamma dimers of heterotrimeric g proteins. | the mitogenic pasteurella multocida toxin (pmt) is a major virulence factor of p. multocida, which causes pasteurellosis in man and animals. the toxin activates the small gtpase rhoa, the map kinase erk and stat proteins via the stimulation of members of two g protein families, g(q) and g(12/13). pmt action also results in an increase in inositol phosphates, which is due to the stimulation of plcbeta via galpha(q). recent studies indicate that pmt additionally activates galpha(i) to inhibit aden ... | 2009 | 19135527 |
| first case of pasteurella multocida endocarditis of the tricuspid valve: a favorable outcome following medical treatment. | we describe a rare case of tricuspid valve endocarditis caused by pasteurella multocida in an elderly woman with no previous history of valvular heart disease. risk factors included contact with animals and old age. the patient was treated successfully with five days of intravenous ampicillin followed by four weeks of oral ciprofloxacin. | 2009 | 19121968 |
| pathological changes in the respiratory tract of goats infected by pasteurella multocida b:2. | clinical and pathological changes are described in groups of five goats pretreated with dexamethasone and then infected with a large dose of pasteurella multocida b:2 (the cause of haemorrhagic septicaemia) by the intratracheal, subcutaneous or intranasal route (groups a, b and c, respectively). in group a, two goats died (on day 1 and 4 post-inoculation); in group b three died (days 2, 5 and 14); and in group c one died (day 20). the infecting organism was recovered from the four goats that die ... | 2009 | 19110260 |
| [84-year old woman with necrotic ulcer on the left lower limb]. | 2008 | 19100137 | |
| pasteurellaceae come1 proteins combine the properties of fibronectin adhesins and dna binding competence proteins. | a novel fibronectin-binding protein from pasteurella multocida (pm1665) that binds to the fibronectin type iii(9-10) modules via two helix-hairpin-helix motifs has recently been described [1]. this protein shares homology with competence-related dna-binding and uptake proteins (comea and come) from gram-positive and gram-negative bacteria. here, we show that recombinant pm1665 (now designated come1) also binds to dna through the same helix-hairpin-helix motifs required for fibronectin-binding. t ... | 2008 | 19098981 |
| histophilus somni biofilm formation in cardiopulmonary tissue of the bovine host following respiratory challenge. | biofilms form in a variety of host sites following infection with many bacterial species. however, the study of biofilms in a host is hindered due to the lack of protocols for the proper experimental investigation of biofilms in vivo. histophilus somni is an agent of respiratory and systemic diseases in bovines, and readily forms biofilms in vitro. in the present study the capability of h. somni to form biofilms in cardiopulmonary tissue following experimental respiratory infection in the bovine ... | 2009 | 19095078 |
| bacterial taxa associated with the hematophagous mite dermanyssus gallinae detected by 16s rrna pcr amplification and ttge fingerprinting. | dermanyssus gallinae (arthropoda, mesostigmata) is suspected to be involved in the transmission of a wide variety of pathogens, but nothing is known about its associated non-pathogenic bacterial community. to address this question, we examined the composition of bacterial communities in d. gallinae collected from standard poultry farms in brittany, france. genetic fingerprints of bacterial communities were generated by temporal temperature gradient gel electrophoresis (ttge) separation of indivi ... | 2009 | 19027065 |
| [pasteurella multocida meningitis in a 93-year-old woman following a cat bite]. | pasteurella multocida is commensal of the normal nasopharynx or gastrointestinal flora in many domestic and wild animals. cat and dog bites usually cause soft tissue infections. p. multocida is an unusual causative agent of meningitis which tends to affect neonates or aged patients. the authors report a case (a 93-year-old woman) of p. multocida meningitis induced by a cat bite with dramatic sequels leading to complete patient disability. | 2009 | 19013736 |
| in vitro activities of tulathromycin and ceftiofur combined with other antimicrobial agents using bovine pasteurella multocida and mannheimia haemolytica isolates. | the purpose of this study was to determine the activities of two antibacterial agents used in the treatment of bovine respiratory infections-tulathromycin, a macrolide, and ceftiofur, a third-generation cephalosporin-alone, in combination with each other, and in combination with each of seven additional antibiotics (tilmicosin, florfenicol, enrofloxacin, danofloxacin, ampicillin, tetracycline, and penicillin g) against bovine pasteurella multocida (n = 60) and mannheimia haemolytica (n = 10) iso ... | 2008 | 19003782 |
| efficacy of metaphylactic florfenicol therapy during natural outbreaks of bovine respiratory disease. | the efficacy of an injectable formulation of florfenicol (300 mg/ml) as metaphylactic control of naturally occurring bovine respiratory disease (brd) was evaluated in two double-blind randomly controlled field studies on two dutch veal calf herds (a and b). cattle aged not older than 3 months and in the direct presence of calves with clinical respiratory disease were randomly allocated to treatment with 40 mg/kg florfenicol subcutaneously (s.c.) a positive control treatment (12.5 mg/kg tilmicosi ... | 2008 | 19000268 |
| [expression and purification of an adhesive protein of rabbit pasteurella multocida c51-3 and detection of its antigenicity]. | the cp36 gene encoding an adhesive protein was amplified by pcr from genomic dna of rabbit p. multocida c51-3 strain, and cloned into the pmd18-t vector and then sequenced. the mature adhesive protein without a signal peptide of cpm36 gene was amplified by pcr from the recombinant plasmid pmd18-cp36, then cloned into the prokaryotic expression vector pqe30 to provide a recombinant plasmid pqe30-cpm36. the recombinant protein of cpm36 was produced in escherichia coli m15 harboring the recombinant ... | 2008 | 18998549 |
| pattern classification of phylogeny signals. | in this paper we propose the minimum entropy clustering (mec) method for clustering genes based on their phylogenetic signals. this entropy based method will cluster two genes together when their concatenation can decrease the entropy. an integral feature of mec is that it chooses the number of clusters automatically, which is a major advantage over the other methods. our simulation results show that this method is quite successful in clustering genes with a common phylogeny. | 2008 | 18976226 |
| complete chemoenzymatic synthesis of the forssman antigen using novel glycosyltransferases identified in campylobacter jejuni and pasteurella multocida. | we have identified an alpha1,4-galactosyltransferase (cgtd) and a beta1,3-n-acetylgalactosaminyltransferase (cgte) in the lipooligosaccharide (los) locus of campylobacter jejuni lio87. strains that carry these genes may have the capability of synthesizing mimics of the p blood group antigens of the globoseries glycolipids. we have also identified an alpha1,3-n-acetylgalactosaminyltransferase (pm1138) from pasteurella multocida pm70, which is involved in the synthesis of an los-bound forssman ant ... | 2009 | 18955372 |
| histidine residues at the active site of the pasteurella multocida toxin. | we have investigated histidine residues near the active site of the mitogenic pasteurella multocida toxin. mutation of h1202 or h1228 had little effect, while the effect of mutation on h1223 depended on the amino acid substituted. mutation of h1205 caused complete loss of activity, indicating its importance in pmt activity. | 2007 | 18949067 |
| quantification and characterization of enzymatically produced hyaluronan with fluorophore-assisted carbohydrate electrophoresis. | hyaluronan (ha) is a polysaccharide with high-potential medical applications, depending on the chain length and the chain length distribution. special interest goes to homogeneous ha oligosaccharides, which can be enzymatically produced using pasteurella multocida hyaluronan synthase (pmhas). we have developed a sensitive, simple, and fast method, based on fluorophore-assisted carbohydrate electrophoresis (face), for characterization and quantification of polymerization products. a chromatograph ... | 2009 | 18948072 |
| mannan-binding lectin (mbl) in two chicken breeds and the correlation with experimental pasteurella multocida infection. | the present study is the first demonstration of an association of the genetic serum mannan-binding lectin (mbl) concentration with bacterial infections in chickens. the genetic serum mbl concentration was determined in two chicken breeds, and the association with the specific pasteurella multocida humoral immune response during an experimental infection was examined. furthermore, we examined the association of the genetic serum mbl concentration with systemic infection. the chickens with systemi ... | 2010 | 18922580 |
| comparison of mouse-protective tests and chick-protective tests of over 600 chemicals against pasteurella multocida. | 1948 | 18886539 | |
| penicillin in the treatment of experimental infections with pasteurella multocida. | 1948 | 18877801 | |
| the effect of streptomycin on pasteurella multocida in vitro, and on fowl cholera in turkeys. | 1948 | 18873072 | |
| recurrent septicemia and osteomyelitis caused by pasteurella multocida in a patient with chronic lymphatic leukemia. | 2008 | 18847173 | |
| pasteurella multocida sepsis--should immunocompromised patients give up their pets? | 2008 | 18847171 | |
| bacteremic community-acquired pneumonia due to pasteurella multocida. | an 87-year-old man was admitted to hospital because of fever, productive cough, dyspnea and altered consciousness. his medical history was significant for chronic obstructive pulmonary disease. he owned several pets. physical examination and a chest radiograph revealed right upper lobe pneumonia. blood cultures taken on admission yielded pasteurella multocida and antimicrobial susceptibility testing showed susceptibility to beta-lactams. the fever subsided four days after treatment with intraven ... | 2009 | 18845465 |
| safety and efficacy testing of a novel multivalent bovine bacterial respiratory vaccine composed of five bacterins and two immunogens. | bovine bacterial respiratory diseases have been one of the most serious problems due to their high mortality and economic loss in calves. the vaccinations of bovine bacterial respiratory vaccines have been complex because of no multivalent vaccine. in this study, novel multivalent bovine bacterial respiratory vaccine (brv) was developed and tested for its safety and efficacy. brv was composed of two immunogens and five bacterins. these were leukotoxoid and bacterin of mannheimia haemolytica type ... | 2008 | 18840971 |
| antibiograms of pathogenic bacteria isolated from laboratory rabbits in ibadan, nigeria. | antibiotic sensitivity patterns of 21 bacterial isolates from some clinically ill new zealand rabbits were evaluated against 12 commonly used antibiotics by the kirby-bauer disk-diffusion sensitivity testing method. the 21 isolates consisted of six bordetella bronchiseptica, eight pasteurella multocida, four staphylococcus aureus and three pseudomonas alcaligenes that were associated with snuffles, pneumonia, otitis media, genital infections and conjunctivitis in these groups of caged rabbits. t ... | 2008 | 18840619 |
| fatal fulminant sepsis due to a cat bite in an immunocompromised patient. | pasteurella multocida infections in humans can present as localized infections of soft tissues surrounding the lesions, as respiratory tract infections or as systemic infections with slow or fulminant development. over 90% of human infections are cases of wound infections or abscesses related to a bite, scratch, or licking of skin lesions by a cat or dog. severe systemic diseases such as pneumonia, lung abscess, peritonitis, endocarditis, meningitis and sepsis are also well known, especially in ... | 2008 | 18820856 |
| why your housecat's trite little bite could cause you quite a fright: a study of domestic felines on the occurrence and antibiotic susceptibility of pasteurella multocida. | approximately four to five million animal bite wounds are reported in the usa each year. domestic companion animals inflict the majority of these wounds. although canine bites far outnumber feline bites, unlike the dog, the cat's bite is worse than its bark; 20-80% of all cat bites will become infected, compared with only 3-18% of dog bite wounds. pasteurella multocida is the most commonly cultured bacterium from infected cat bite wounds. anyone seeking medical attention for a cat-inflicted bite ... | 2008 | 18811910 |
| influence of systemic fluoroquinolone administration on the presence of pasteurella multocida in the upper respiratory tract of clinically healthy calves. | the influence of enrofloxacin administration (5 mg/kg) for five consecutive days on the occurrence of pasteurella multocida in the upper respiratory tract of two healthy calves was monitored over a 10-day period. from nasal swabs of two additional healthy control calves, which received a placebo saline administration, p. multocida was isolated throughout the study period. in the enrofloxacin treated calves, p. multocida was not demonstrated in the nasopharynx from 48 h after the first injection ... | 2008 | 18808692 |
| sepsis of total knee arthroplasty after domestic cat bite: should we warn patients? | 2008 | 18795185 | |
| molecular analysis of florfenicol-resistant pasteurella multocida isolates in germany. | three florfenicol-resistant pasteurella multocida isolates from germany, two from swine and one from a calf, were investigated for the genetics and transferability of florfenicol resistance. | 2008 | 18786941 |
| an avirulent live pasteurella multocida vaccine for drinking water and aerosol administration against turkey cholera. | a naturally avirulent isolant of pasteurella multocida (heddleston sero-type 3) was investigated as a seed strain for the development of a live vaccine against turkey pasteurellosis. laboratory trials showed that when given in aerosol form at a dosage of 5 x 10(8) c.f.u. per m(2), of barn floor, the vaccine produced satisfactory protection against both homologous and heterologous serotypes challenge administered by aerosol. likewise, turkeys vaccinated once, twice or three times, and challenged ... | 1979 | 18770466 |
| studies on pasteurella gallinarum. | in two outbreaks of disease in chickens associated with pasteurella gallinarum infection swollen and inflamed wattles were symptoms. a bacteriological study was carried out of 42 p. gallinarum strains isolated from the two outbreaks and from sporadic cases in fowls. serotyping by the gel diffusion precipitin test indicated that all five strains from one outbreak and 82% of isolants from 22 sporadic cases belonged to one serotype, antigenically unrelated to pasteurella multocida. all four isolant ... | 1977 | 18770350 |
| reticuloendotheliosis antigen for the agar gel precipitation test. | an antigen for gel precipitation was prepared from chick embryo fibroblast cultures inoculated with the reticuloendotheliosis virus. the specificity of the reaction was confirmed with reference reticuloendotheliosis and spleen necrosis sera. no precipitation reactions occurred between this antigen and marek's disease, newcastle disease, infectious bronchitis, pasteurella multocida and haemorrhagic enteritis antisera. | 1977 | 18770334 |
| taxonomy of some recently described avian pasteurella/actinobacillus-like organisms as indicated by deoxyribonucleic acid relatedness. | members of the family pasteurellaceae pohl 1981 are frequently encountered in birds as parasites or pathogens, e.g. the well-known species pasteurella multocida, pasteurella gallinarum, haemophilus paragallinarum, and three species containing strains that had been previously classified as "haemophilus avium"(pasteurella avium, pasteurella volantium, and an unnamed pasteurella species defined by mutters et al., 1985). a variety of additional taxa which had been tentatively assigned to the family ... | 1985 | 18766923 |
| acute septicaemic pasteurella multocida infection in an african grey parrot (psittacus erithacus timneh) after a bite from a pet rat (rattus norvegicus). | p. multocida infections in man and birds as a sequel to animal bites are reviewed and a case report is presented of a fatal p. multocida septicaemia in a parrot after a bite from a pet rat. the need for immediate intravenous or intramuscular treatment of birds with a penicillin after bites from all mammals is stressed. | 1986 | 18766580 |
| identification of pasteurella multocida isolates of ruminant origin using polymerase chain reaction and their antibiogram study. | a total of 100 isolates of pasteurella multocida from various ruminant species (cattle, buffalo and sheep) belonging to different parts of country were identified using pasteurella multocida-pcr (pm-pcr) and capsular pcr assays. pm-pcr revealed an amplicon of approximately 460 bp in all the isolates tested. as regards capsular pcr, 36 of 38 cattle isolates and 30 of 34 buffalo isolates were found to belong to capsular serogroup b whereas rest of the cattle and buffalo isolates belonged to serogr ... | 2009 | 18759064 |
| characterization of tolc efflux pump proteins from pasteurella multocida. | two tolc homologs, pm0527 and pm1980, were identified for pasteurella multocida. a pm0527 mutant displayed increased susceptibility to a range of chemicals, including rifampin (512-fold) and acridine orange (128-fold). a pm1980 mutant showed increased susceptibility to rifampin, ceftazidime, and vancomycin. | 2008 | 18725450 |
| development and application of a reverse transcriptase polymerase chain reaction to detect chinese isolates of duck hepatitis virus type 1. | we developed a reverse transcriptase polymerase chain reaction (rt-pcr) method for the detection of duck hepatitis virus type 1 (dhv-1) in the tissues of infected and clinically affected ducks and in chick and duck embryos. we found the assay to be effective in detecting the virus in china, where it is being used in studies on the epidemiology of the disease. we applied this simple and rapid diagnostic method to the detection of dhv isolates grown in chick and duck embryos and in tissues obtaine ... | 2009 | 18706944 |
| heterologous protective immunization elicited in mice by pasteurella multocida fur omph. | different strategies have been developed to produce vaccines against pasteurella multocida. the approach described herein involves overexpression on the bacterial cell surface of fur-regulated iromps (iron-regulated outer-membrane proteins). accordingly, the ability of fur mutants to promote heterologous protection was examined in a swiss mouse animal model. twofur mutants derived from p. multocida were isolated, one of which was also defective in the omph protein. in mice challenged with virule ... | 2008 | 18683628 |
| vaccination of young turkeys against fowl cholera. | turkey poults vaccinated at one day of age with commercial inactivated pasteurella multocida (pm) bacterin responded with low titres of antibody (ab) as measured by elisa, but had an acceptable degree of resistance when challenged with the x-73 strain of pm until 13 weeks of age. turkeys vaccinated at 3 and/or 6 weeks of age responded with higher ab titres and were resistant to virulent challenge with pm. turkey poults vaccinated at 3 and/or 6 weeks of age with a commercial live pm vaccine had a ... | 1990 | 18679920 |
| virulence and infectivity of a: 14 strains of pasteurella multocida for turkey poults. | strains of pasteurella multocida, capsular serogroup a and somatic serotype 14, (a: 14) isolated from turkeys which had succumbed to fowl cholera were examined for virulence and infectivity. groups of 2-week-old poults were injected intramuscularly with one of three strains. slight to moderate virulence, based on mortality, was noted. poults that survived exposure were frequently affected with exudative airsacculitis. intramuscular, intra-air sac and intranasal exposure of 6-week-old poults with ... | 1989 | 18679893 |
| neurological bacterial diseases in possums and gliders: a review of eight cases. | 2008 | 18673470 | |
| molecular phylogenetic analysis of tryptophanyl-trna synthetase of actinobacillus actinomycetemcomitans. | aminoacyl-trna synthetase family enzymes are of particular interest for creating universal phylogenetic trees and understanding the gene flow as these enzymes perform the basic and analogous biochemical function of protein synthesis in all extant organisms. among them, tryptophanyl-trna synthetase (trp-rs) plays a foremost role in phylogeny owing to the close relationship with tyrosine-trna synthetase. in this study, the sequence of the gene trp-rs was amplified using degenerated adenylation dom ... | 2008 | 18669030 |
| salpingitis in web-footed birds: prevalence, aetiology and significance. | among 4,893,447 ducks slaughtered during a 10 year period in a single slaughterhouse in denmark 7,190 (0.15%) were condemned because of salpingitis. a further 21,658 ducks (0.44%) were approved for human consumption after the inflamed salpinx had been removed. annual condemnation due to salpingitis varied from 0 to 0.53% and total condemnation varied from 1.30 to 2.72%, with an average of 1.98%. sixteen different bacterial species were isolated in pure culture from salpingitis in 7 week-old duck ... | 1995 | 18645801 |
| membrane morphology and leukotoxin secretion are associated with a novel membrane protein of aggregatibacter actinomycetemcomitans. | gram-negative bacteria display either a flat or an irregular outer membrane. the periodontal pathogen aggregatibacter (actinobacillus) actinomycetemcomitans has an irregular outer membrane. we have identified a gene that is associated with the biogenesis of this morphology. the gene is part of a three-gene operon and codes for a 141-kda protein designated morphogenesis protein c (morc), which is conserved in several gram-negative bacteria including haemophilus influenzae and pasteurella multocid ... | 2008 | 18621903 |
| usage of antimicrobials and occurrence of antimicrobial resistance among bacteria from mink. | the usage of antimicrobials for treatment of mink and the occurrence of antimicrobial resistance among the most important bacterial pathogens in mink was investigated. the aim of the study was to provide data, which may serve as a basis for the formulation of recommendations for prudent use of antimicrobials for mink. a total of 164 haemolytic staphylococci, 49 haemolytic streptococci, 39 pseudomonas aeruginosa, 13 pasteurella multocida, and 1093 escherichia coli isolates from danish mink were i ... | 2009 | 18620819 |
| prevalence of antimicrobial resistance among bacterial pathogens isolated from cattle in different european countries: 2002-2004. | the project "antibiotic resistance in bacteria of animal origin - ii" (arbao-ii) was funded by the european union (fair5-qlk2-2002-01146) for the period 2003-2005, with the aim to establish a continuous monitoring of antimicrobial susceptibility among veterinary laboratories in european countries based on validated and harmonised methodologies. available summary data of the susceptibility testing of the bacterial pathogens from the different laboratories were collected. | 2008 | 18611246 |
| vaccination with pasteurella multocida recombinant ompa induces strong but non-protective and deleterious th2-type immune response in mice. | pasteurella multocida ompa (pmompa) belongs to the major and multifunctional escherichia coli ompa family of proteins. we have previously reported that the protein is conserved, immunogenic and an adhesin that binds host cells and host cell extracellular matrix molecules [dabo sm, confer aw, quijano-blas ra. molecular and immunological characterization of pasteurella multocida serotype a:3 ompa: evidence of its role in p. multocida interaction with extracellular matrix molecules. microb pathog 2 ... | 2008 | 18598730 |
| effect of age at the time of vaccination on antibody titers and feedlot performance in beef calves. | to compare antibody responses, feedlot morbidity and mortality rates, feedlot performance, and carcass value for calves vaccinated with 1 of 2 vaccination strategies and for unvaccinated control calves. | 2008 | 18593324 |
| what is your diagnosis? respiratory abscess. | 2008 | 18593309 | |
| respiratory pasteurellosis: infection or colonization? | respiratory infection by pasteurella multocida is uncommon and usually occurs in patients with an underlying lung disease, advanced age and/or immunodepression. in this study, we describe the clinical and microbiological characteristics of a series of 14 patients in whom pasteurella multocida was isolated from lower respiratory tract samples, over a period of 21 y (1986-2006). differentiation between colonization and infection allows establishment of early antibiotic treatment. | 2008 | 18584547 |
| activation of galpha (i) and subsequent uncoupling of receptor-galpha(i) signaling by pasteurella multocida toxin. | bacterial protein toxins are powerful tools for elucidating signaling mechanisms in eukaryotic cells. a number of bacterial protein toxins, e.g. cholera toxin, pertussis toxin (ptx), or pasteurella multocida toxin (pmt), target heterotrimeric g proteins and have been used to stimulate or block specific signaling pathways or to demonstrate the contribution of their target proteins in cellular effects. pmt is a major virulence factor of p. multocida causing pasteurellosis in man and animals and is ... | 2008 | 18583341 |
| effects of commingling beef calves from different sources and weaning protocols during a forty-two-day receiving period on performance and bovine respiratory disease. | the study objective was to determine health and performance of ranch calves from different preconditioning strategies during a 42-d receiving period when commingled with calves of unknown health histories from multiple sources. steer calves from a single source ranch (ranch) were weaned and immediately shipped to a feedlot (wean, initial bw = 247 +/- 29 kg); weaned on the ranch for 45 d before shipping, but did not receive any vaccinations (wean45, initial bw = 231 +/- 26 kg); or weaned, vaccina ... | 2008 | 18567723 |
| pasteurella multocida sialic acid aldolase: a promising biocatalyst. | sialic acid aldolases or n-acetylneuraminate lyases (nanas) catalyze the reversible aldol cleavage of n-acetylneuraminic acid (neu5ac) to form pyruvate and n-acetyl-d: -mannosamine (mannac). a capillary electrophoresis assay was developed to directly characterize the activities of nanas in both neu5ac cleavage and neu5ac synthesis directions. the assay was used to obtain the ph profile and the kinetic data of a nana cloned from pasteurella multocida p-1059 (pmnana) and a previously reported reco ... | 2008 | 18521592 |
| a comparison of 2 vaccination programs in feedlot calves at ultra-high risk of developing undifferentiated fever/bovine respiratory disease. | the aim of this study was to compare 2 vaccination programs in feedlot calves at ultra-high risk of developing undifferentiated fever (uf)/bovine respiratory disease (brd). at feedlot arrival, 3882 calves were enrolled in the study and randomly allocated to 2 groups, which were housed by group in 12 pens. at the time of allocation, 1 group (mlv3-bt2) received a multivalent, modified-live viral vaccine containing infectious bovine rhinotracheitis virus (ibrv) and types i and ii bovine viral diarr ... | 2008 | 18512457 |
| proliferation and transmission patterns of pasteurella multocida b:2 in goats. | this report describes the proliferation and transmission patterns of pasteurella multocida b:2 among stressful goats, created through dexamethasone injections. thirty seven clinically healthy adult goats were divided into three groups consisted of 15 goats in group a, 11 goats in group b and the remaining 11 in group c. at the start of the study, all goats of group a were exposed intranasally to 1.97 x 10(10) cfu/ml of live p multocida b:2. dexamethasone was immediately administered intramuscula ... | 2008 | 18509941 |
| prevalence of actinobacillus pleuropneumoniae, actinobacillus suis, haemophilus parasuis, pasteurella multocida, and streptococcus suis in representative ontario swine herds. | tonsillar and nasal swabs were collected from weanling pigs in 50 representative ontario swine herds and tested for the presence of 5 important bacterial upper respiratory tract pathogens. all but 1 herd (2%) tested positive for streptococcus suis by polymerase chain reaction (pcr); 48% of herds were s. suis serovar 2, 1/2 positive. in all but 2 herds there was evidence of haemophilus parasuis infection. in contrast, toxigenic strains of pasteurella multocida were detected by a p. multocida--enz ... | 2008 | 18505187 |
| a compendium of antibiotic-induced transcription profiles reveals broad regulation of pasteurella multocida virulence genes. | the transcriptional responses of pasteurella multocida to eight antibiotics with known mode of actions (moas) and one novel antibiotic compound with an unknown moa were collected to create a compendium of transcriptional profiles for moa studies. at minimal inhibitory concentration the three bactericidal compounds enrofloxacin, cefquinome and the novel compound had a minor impact on gene regulation with approximately 1% of the p. multocida genome affected, whilst the bacteriostatic compounds flo ... | 2008 | 18501535 |
| detection by in-situ hybridization of pasteurella multocida toxin (toxa) gene in the lungs of naturally infected pigs. | in-situ hybridization with a non-radioactive digoxigenin-labelled probe was used to detect the pasteurella multocida toxin (pmt) gene in tissue sections of pneumonic lung from pigs naturally infected with toxigenic p. multocida. the morphology of host cells was preserved despite the relatively high temperature used in the incubation procedure. pulmonary abscessation was observed in 13 pigs naturally infected with toxigenic p. multocida type a (three pigs) or d (10 pigs). in these 13 pigs a stron ... | 2008 | 18495148 |
| meningitis and subgaleal, subdural, epidural empyema due to pasteurella multocida. | pasteurella is a gram-negative coccobacillus found in 70-90% of oral cavities of cats, and as well, is isolated from the digestive systems of dogs, rats, rabbits, monkeys, and other animals. pasteurella multocida has been known to cause infections in humans, the most familiar being soft tissue infection after animal bites. however, this organism may affect a variety of systems, causing serious disease. pasteurella multocida can cause septic arthritis, osteomyelitis, pneumonia, endocarditis, meni ... | 2010 | 18486411 |
| phenotypic and genotypic characters of isolates of pasteurella multocida obtained from back-yard poultry and from two outbreaks of avian cholera in avifauna in denmark. | two outbreaks of fowl cholera in the avifauna in denmark, affecting primarily eiders but also cormorants, gulls and oyster-catchers were shown to be caused by the same clone of pasteurella multocida ssp. multocida by restriction enzyme analysis (rea) and ribotyping, using the enzymes hpaii and hhai and phenotypic characterization. this observation indicated spread by migratory birds. it was shown that the outbreak clone was closely related to isolates of pasteurella multocida ssp. multocida obta ... | 1998 | 18484015 |
| effect of centchroman on cellular and humoral immunity. | centchroman (ormeloxifene) is a nonsteroidal selective estrogen receptor modulator that is used as once a week oral contraceptive agent. the effect of centchroman on the immune system was evaluated by using different experimental models such as carbon clearance test, cyclophosphamide induced neutropenia, neutrophil adhesion test, effect on serum immunoglobulins, mice lethality test and indirect haemagglutination test. the first three models namely carbon clearance test, cyclophosphamide induced ... | 2007 | 18476393 |
| pasteurella multocida bacteremia in a patient with ovarian cancer and chemotherapy-induced neutropenia. | background:pasteurella multocida is a commensal organism found in the saliva and oropharynx of domestic animals. it causes a variety of human infections ranging from cellulitis to bacteremia and sepsis. the severity of infection is somewhat related to the immunocompetency of the infected host. an immunocompromised host is more likely to suffer a disseminated infection as a result of contact with this organism than an immunocompetent host. this case report and review of the literature are present ... | 1995 | 18472893 |
| effects of subminimum inhibitory concentrations of antibiotics on the pasteurella multocida proteome: a systems approach. | to identify key regulators of subminimum inhibitory concentration (sub-mic) antibiotic response in the pasteurella multocida proteome, we applied systems approaches. using 2d-lc-esi-ms(2), we achieved 53% proteome coverage. to study the differential protein expression in response to sub-mic antibiotics in the context of protein interaction networks, we inferred p. multocida pm70 protein interaction network from orthologous proteins. we then overlaid the differential protein expression data onto ... | 2008 | 18464924 |
| identification of pasteurella multocida chaps-soluble outer membrane proteins. | fowl cholera continues to be of concern to the poultry industry, especially for turkey growers. this disease costs the turkey industry millions of dollars annually. in order to develop improved live attenuated vaccines or subunit vaccines, the outer-membrane proteins of pasteurella multocida were examined with the use of proteomics. of the 11 proteins total present in an outer-membrane subfraction of p. multocida, four additional proteins were identified, completing the composition of the deterg ... | 2008 | 18459313 |
| [celulitis in an 88-year old woman]. | 2008 | 18457640 | |
| [characteristics and immunogenicity of the n-terminal and c-terminal recombinants of pasteurella multocida toxin]. | in this study, five fragments of recombinant subunit pasteurella multocida toxin (pmt) were constructed. only pet28a-n1518 and pet28b-c2115 could be expressed efficiently in escherichia coli. the molecular weight of the fusion proteins was 57 kda and 78 kda .western blot confirmed that the two proteins could specifically react with antiserum against pasteurella multocida toxin. no mice died after the intraperitoneal administration of these two proteins with the dose of 200 microg per mouse, but ... | 2008 | 18438004 |
| using amplified fragment length polymorphism analysis to differentiate isolates of pasteurella multocida serotype 1. | avian cholera, an infectious disease caused by the bacterium pasteurella multocida, kills thousands of north american wild waterfowl annually. pasteurella multocida serotype 1 isolates cultured during a laboratory challenge study of mallards (anas platyrhynchos) and collected from wild birds and environmental samples during avian cholera outbreaks were characterized using amplified fragment length polymorphism (aflp) analysis, a whole-genome dna fingerprinting technique. comparison of the aflp p ... | 2008 | 18436655 |
| magnetic resonance imaging features of spinal epidural empyema in five dogs. | spinal epidural empyema is defined an accumulation of purulent material in the epidural space of the vertebral canal. spinal epidural empyema should be considered as a differential diagnosis in dogs with pyrexia, spinal pain, and rapidly progressing myelopathy. magnetic resonance (mr) imaging is the imaging test of choice in humans. here, we describe the mr imaging features of five dogs with confirmed spinal epidural empyema. the epidural lesions appeared as high or mixed signal masses in t2-wei ... | 2008 | 18418993 |
| protection of chickens from fowl cholera by vaccination with recombinant adhesive protein of pasteurella multocida. | the recombinant adhesive protein (rcp39) of pasteurella multocida strain p-1059 (serovar a:3) was prepared and purified with a hybrid condition of affinity chromatography. the rcp39 was highly protective for chickens from fowl cholera by challenge-exposure with parental strain p-1059 or heterologous strain x-73 (serovar a:1) compared to various kind of vaccines. sixteen groups of ten chickens each were subcutaneously inoculated twice with 100, 200 or 400 microg proteins of rcp39, native cp39, na ... | 2008 | 18403068 |
| atrophic rhinitis vaccine composition triggers different serological profiles that do not correlate with protection. | atrophic rhinitis (ar) is a widespread and economically important disease of swine caused by bordetella bronchiseptica and pasteurella multocida. it can be controlled by vaccination. this study investigates the effect of altering the composition (adjuvants and/or addition of formalin-inactivated p. multocida toxin, fpmt) of conventional vaccines on the serological profile and on protection against ar in swine. a significantly higher b. bronchiseptica specific antibody titre was detected for vacc ... | 2008 | 18401954 |
| protein kinase d links gq-coupled receptors to camp response element-binding protein (creb)-ser133 phosphorylation in the heart. | many growth regulatory stimuli promote camp response element-binding protein (creb) ser(133) phosphorylation, but the physiologically relevant creb-ser(133) kinase(s) in the heart remains uncertain. this study identifies a novel role for protein kinase d (pkd) as an in vivo cardiac creb-ser(133) kinase. we show that thrombin activates a pkcdelta-pkd pathway leading to creb-ser(133) phosphorylation in cardiomyocytes and cardiac fibroblasts. alpha(1)-adrenergic receptors also activate a pkcdelta-p ... | 2008 | 18378685 |
| the c3 domain of pasteurella multocida toxin is the minimal domain responsible for activation of gq-dependent calcium and mitogenic signaling. | the large 1285-amino-acid protein toxin from pasteurella multocida (pmt) is a multifunctional single-chain polypeptide that binds to and enters eukaryotic cells and acts intracellularly to promote g(q) and g(12/13) protein-dependent calcium and mitogenic signal transduction. previous studies indicated that the intracellular activity domain responsible for pmt action was located within the c-terminal 600-700 amino acids. in this study, we have exogenously expressed a series of n- and c-terminal p ... | 2008 | 18369188 |
| pasteurella multocida septic shock after a cat scratch in an elderly otherwise healthy woman: a case report. | pasteurella multocida, a gram-negative coccobacillus, is a commensal in the nasopharynx of many animals. p. multocida infections most commonly involve the skin, soft tissues, and respiratory tract, particularly in immunosuppressed patients. the present case illustrates a severe articular infection caused by this bacterium, leading to septic shock, in an elderly, otherwise healthy woman, after a simple scratch of a cat. | 2008 | 18358966 |
| evaluation of different api systems for identification of porcine pasteurella multocida isolates. | an exhaustive biochemical characterisation of 60 porcine pasteurella multocida clinical isolates recovered from lesions indicative of pneumonia, previously confirmed by pcr and all belonging to the capsular serogroup a, was performed by means of four commercial systems. the api 20ne correctly identified almost all isolates (95%), but only 60% could be ascribed to this species by the api 20e method. the high diversity exhibited by the api 50chb/e system, with six different patterns, does not advi ... | 2008 | 18343468 |
| associations between pathogens in healthy pigs and pigs with pneumonia. | the aim of this study was to evaluate the associations between different pathogens in the development of pneumonia and bronchopneumonia in pigs. samples of bronchoalveolar lavage fluid from 100 pigs showing no clinical signs and 239 pigs with clinical signs of respiratory disease were examined for mycoplasma hyopneumoniae, mycoplasma hyorhinis, us-type porcine respiratory and reproductive syndrome virus (prrsv), eu-type prrsv, porcine circovirus type 2 (pcv-2), influenza virus type a, alpha-haem ... | 2008 | 18310558 |
| structural analysis of sialyltransferase pm0188 from pasteurella multocida complexed with donor analogue and acceptor sugar. | pm0188 is a newly identified sialyltransferase from p. multocida which transfers sialic acid from cytidine 5'-monophosphonuraminic acid (cmp-neuac) to an acceptor sugar. although sialyltransferases are involved in important biological functions like cell-cell recognition, cell differentiation and receptor-ligand interactions, little is known about their catalytic mechanism. here, we report the x-ray crystal structures of pm0188 in the presence of an acceptor sugar and a donor sugar analogue, rev ... | 2008 | 18304450 |
| [acclimating, screening of dominant bacteria for degrading phthalic acid esters and study on its degradation]. | to define the method of acclimating isolating and screening of dominant bacteria for phthalic acid esters biodegradation and study their plasmids. | 2007 | 18303624 |
| terpenoid compositions, and antioxidant and antimicrobial properties of the rhizome essential oils of different hedychium species. | a phytochemical study of the rhizome essential oils of four different hedychium species was performed by means of gc and gc/ms analyses. h. ellipticum mainly contained 1,8-cineole, sabinene, and terpin-4-ol, while h. aurantiacum possessed terpin-4-ol, para-cymene, and bornyl acetate as the major entities. similarly, trans-meta-mentha-2,8-diene and linalool were noticed in h. coronarium. three different collections (i-iii) of h. spicatum showed amazing differences in the relative contents of thei ... | 2008 | 18293443 |
| promotion of immunity of mice to pasteurella multocida and hog cholera vaccine by pig interleukin-6 gene and cpg motifs. | a novel oligodeoxynuleotides containing 11 cpg motifs was synthesized and inserted into the vr1020 plasmid containing pig interleukin-6 (il-6) gene (vpil6) to construct recombinant plasmid, vpil6c. the chitosan nanoparticles (cnp) were prepared by ionic cross linkage to entrap the vpil6c (vpil6c-cnp), vpil6 (vpil6-cnp) and cpg (cpg-cnp). 42-day old female mice were divided into four groups and intramuscularly injected respectively with 6 pmol vpil6c-cnp, vpil6-cnp, cpg-cnp and vr1020-cnp along w ... | 2009 | 18279956 |
| anion secretion evoked by pasteurella multocida toxin across rat colon. | stimulation of muscarinic receptors is known to have a biphasic effect on colonic cl(-) secretion: a short-lasting activation, which is followed by a long-lasting inhibition. in order to find out, which role gq proteins play in both processes, pasteurella multocida toxin was used, a known activator of g alpha q. this toxin (1.5 microg/ml) had a dual action on short-circuit current (isc) across rat distal colon: it stimulated transiently isc and subsequently down-regulated the isc evoked by ca2+- ... | 2008 | 18279849 |
| phenotypic and genotypic characterisation of pasteurella multocida strains isolated from pigs in hungary. | a total of 146 pasteurella multocida strains isolated from swine in hungary in the last 20 years were examined. biochemical characterisation and pcr-based techniques were used to determine species, subspecies, biovar, capsule type and presence of the toxa gene. eighty-seven percent of the isolates belonged to p. multocida ssp. multocida, and 98% of these had biovar 3 or were trehalose- or lactose-fermenting or ornithine decarboxylase negative variants of that. ten percent of the strains were p. ... | 2007 | 18277702 |
| evaluation of pyelonephritis in culled indoor and outdoor high parity sows. | the present trial was conducted in hungary in neighboring large indoor and outdoor pig production units, belonging to the same breeding company. rejected kidneys from 201 (out of 241; 83.4%) outdoor, and 191 (out of 512, 37.3%) indoor high parity sows, with previous history of recidiving postparturient fever and excessive postparturient vulvovaginal discharge were gross pathologically bacteriologically, and histologically evaluated. all rejected kidneys revealed chronic pyelonephritis. in outdoo ... | 2008 | 18265757 |