Publications

[somatic antigens of shigella and escherichia coli. determination of the structure of o-specific polysaccharide from shigella boydii type 12 and its serological properties compared with the o-specific polysaccharide from escherichia coli].	the structure of the o-specific polysaccharide of the somatic antigen (lipopolysaccharide) of shigella boydii, type 12, was established by 1h- and 13c-nmr, methylation analysis and partial acid hydrolysis methods. the polysaccharide consists of pentasaccharide repeating units of the following structure: (formula; see text) the amount of o-acetyl groups was far less than stoichiometric, only about 2 for 3-4 repeating units. nevertheless, the results of serological studies revealed 3-o-acetyl-alph ...	1986	2430583
predicted conformations for the immunodominant region of the circumsporozoite protein of the human malaria parasite plasmodium falciparum.	the circumsporozoite protein of the human malaria parasite plasmodium falciparum contains multiple tandem repeats of the amino acid sequence asn-ala-asn-pro. the repeated sequence encompasses the immunodominant region of the protein, and antibodies raised against it are potent inhibitors of invasion and development of sporozoites in cultured hepatocytes. using a modified build-up procedure, we have explored a large number of possible helical and near-helical conformations of a terminally blocked ...	1986	2426702
tissue integration of a12o3-ceramic dental implants (frialit)--a case report.	the tissue intraosseous integration of a12o3-ceramic dental implants (frialit) is studied in a patient case, where an implant-fracture made it necessary to remove the implant from a patient's jaw. the surgical removing of the apical part of the implant with the use of a trepan bur made it possible to examine and visualize histologically and microradiographically the tissue adjacent to the implant. the results of both the histological and microradiographical studies showed that a good healing and ...	2007	2374995
kinetics of "p"-site-mediated inhibition of adenylyl cyclase and the requirements for substrate.	the kinetics of "p"-site-mediated inhibition of adenylyl cyclase was studied with the detergent-solubilized enzyme from rat brain. mn2(+)-activated adenylyl cyclase exhibited typical noncompetitive inhibition by 2'-d3'-amp or 2',5'-dideoxyadenosine (2',5'-ddado). however, enzyme that was preactivated with guanosine 5'-o-(3-thiotriphosphate) (gtp gamma s) or proteolytically with ninhibin (+ gtp gamma s) exhibited apparently uncompetitive inhibition with either 2'-d3'-amp or 2',5'-ddado and with e ...	1990	2365688
[study of the blink reflex in spinocerebellar degeneration].	blink reflex (br) was composed of r1 and r2. r1 is considered to indicate the brainstem function. the purpose of this study was to evaluate the brainstem function of spinocerebellar degeneration (scd) by the r1 latency (r1). br was evoked by the percutaneous stimulation of supraorbital nerve. and r1 was measured by the action potential of orbucularis oculi muscle. direct response was recorded by the percutaneous stimulation of facial nerve to determine the terminal latency of facial nerve (d). b ...	2008	2364628
[current views on the pathomorphology and pathogenesis of dysentery].	according to the literature and the authors' data in patients who died of dysentery shigellae are found seldom because of postmortem shedding of superficial colonic epithelium infected by them. shigella adhesion and invasion into the colonocytes are regularly found in the colon biopsies. as shown recently in experiments, shigella outer membrane proteins forming "contact haemolysin" ("virulence plasmid" product) are responsible for their invasion. in the small intestine this cytotoxin is destroye ...	1990	2281980
structural aspects of pathology in alzheimer's disease.	the characteristic lesions of alzheimer's disease, neurofibrillary tangles and neuritic plaques, are the sites of accumulation of abnormal fibrillar material. the structure of the paired helical filament from tangles has been analysed by electron microscopy and biochemical studies have shown that it contains microtubule associated protein tau as a component. fibrils of beta-amyloid in the neuritic plaque arise by polymerization of a small proteolytic fragment of a much larger precursor protein. ...	2008	2268679
[bacteriology and epidemiology of shigellas isolated at the army hospital in djibouti].	in a space of 26 months 108 shigellas were isolated from 104 patients with sporadic and benign diseases. 90% of the subjects were young french. both s. dysenteriae and s. boydii make up 21% of the strains studied. 13% of the germs are multiresistance. multiresistance can enhance development of serious sickness if a virulent strain comes in.	1990	2263188
glucocorticoid-regulated gene expression in the immune system. analysis of glucocorticoid-regulated transcripts from the mouse macrophage-like cell line p388d1.	to further elucidate the molecular mechanisms underlying glucocorticoid-mediated immune suppression, we have exploited cdna cloning and subtractive screening methods to identify glucocorticoid-regulated transcripts in the mouse macrophage-like cell line, p388d1. two of the three isolated glucocorticoid-regulated mrna species corresponded to genes potentially important to immunoregulation: one glucocorticoid-suppressed mrna species probably encoded the previously uncloned 3-hydroxy-3-methylglutar ...	1990	2258621
[a new serotype of shigella boydii].	two strains which belong to the same serotype of shigella were isolated from the bloody-pus stool of two patients (in 1986) and is reported in this paper. the results were identical both showing agglutination in low titer with serotype 8 of s. dysenteriae and serotype 4 of s. boydii when the two strains were checked well with all kinds of diagnostic antisera and vice versa, ie the antisera produced by the two strains were also checked well with sera prepared with the representative strains of al ...	1990	2251827
[bacillary dysentery--1988].		1990	2251385
the monitoring of foodhandlers in papua new guinea.	in early 1987 guidelines were re-enforced for pre-employment medicals and 6-monthly health checks on foodhandlers in the ok tedi mining project in papua new guinea. the health monitoring program was stepped up as a result of two typhoid cases imported from the highlands and catering subcontractors failing to comply with the necessary pre-placement medicals for foodhandlers. highlanders made up 28% (49/174) of the ok tedi catering department's workforce in 1987. the initial screen of 155 foodhand ...	1990	2238835
age, sex, and region adjusted concentrations of chromium and nickel in lung tissue.	chromium (cr) and nickel (ni) concentrations were measured in lung tissue from 110 random necropsies by means of atomic absorption spectrometry. the subjects originated from the ruhr district (bochum (71 cases) and dortmund (16 cases) areas), which has been defined as a particular pollution area with locally high cr and ni emissions, and from münster and vicinity (23 cases). the cr and ni concentrations in lung tissue of the subjects from the ruhr district (3.09 (sd 2.99) micrograms cr/g, 0.65 ( ...	2007	2223660
age, sex, and region adjusted concentrations of chromium and nickel in lung tissue.	chromium (cr) and nickel (ni) concentrations were measured in lung tissue from 110 random necropsies by means of atomic absorption spectrometry. the subjects originated from the ruhr district (bochum (71 cases) and dortmund (16 cases) areas), which has been defined as a particular pollution area with locally high cr and ni emissions, and from münster and vicinity (23 cases). the cr and ni concentrations in lung tissue of the subjects from the ruhr district (3.09 (sd 2.99) micrograms cr/g, 0.65 ( ...	2007	2223660
childhood shigellosis: clinical and bacteriological study.	ninety-three children with shigellosis were hospitalized in a regional hospital in kuwait during the year 1988. s. flexneri was the most common isolate (54%) followed by s. sonnei (39%) and s. boydii (7%). in addition to the gastrointestinal manifestations, 14 patients (15%) developed generalized convulsions. the benign and self-limiting nature of the convulsions associated with shigellosis means that neither diagnostic procedure nor drug therapy are usually necessary. the disease was self-limit ...	1990	2202839
plasmid profile analysis and antimicrobial susceptibility patterns of shigella isolates from nigeria.	in an epidemiological survey, plasmid profiles and antimicrobial susceptibility testing of 100 shigella isolates in lagos, nigeria was done. all the isolates were sensitive to nalidixic acid, nitrofurantoin and ciprofloxacin. the commonest antimicrobial susceptibility pattern was resistance to ampicillin, colistin sulphate, co-trimoxazole, streptomycin and tetracycline. all but 4 of 100 isolates screened contained one or more plasmids. plasmid profile analysis distinguished more strains than did ...	1990	2200702
polymerase chain reaction for detection of invasive shigella flexneri in food.	the polymerase chain reaction (pcr) was used to amplify a 760-base-pair (bp) fragment with the 220-kbp invasive plasmids of enteroinvasive escherichia coli, shigella flexneri, shigella dysenteriae, shigella boydii, and shigella sonnei as templates. this pcr product was easily detected by agarose gel electrophoresis. a 210-bp acci-psti fragment lying within the amplified region was used as a probe in southern hybridization blots and showed that the pcr-generated product was derived from the invas ...	1990	2200336
[the importance of shigella boydii in shigellosis morbidity in the ussr].	the etiological role of s. boydii in shigella infections registered at different territories of the ussr in 1986-1987 was analyzed. as established by this analysis, s. boydii infection occurred mainly at the territories with unsatisfactory water supply of the population; from these territories the infection spread to ther territories of the ussr. the dominating serovars causing s. boydii dysentery, as well as shigella infections, at different territories of the ussr was shown to be identical, wh ...	1990	2195811
somatostatin receptor incidence and distribution in breast cancer using receptor autoradiography: relationship to egf receptors.	somatostatin receptors (ss-r) were measured with in vitro receptor autoradiography using the ss analog 125i-[tyr3]-sms 201-995 as radioligand in 342 breast-tumor samples. in a group of 158 "small" tumor samples (mean section surface: 14 mm2 +/- 0.4; mean +/- sem), 34 tumors (21%) were ss-r positive. in a group of 72 "large" tumor samples (mean size: 180 mm2 +/- 8; mean +/- sem), 33 tumors (46%) were ss-r positive. in this second group, more than half of the tumors had a non-homogeneous distribut ...	2007	2168344
an attempt to structurally convert mu-selective morphine toward delta-receptor binding: dimerization based on enkephalin conformation.	in order to elucidate the substrate specificities for mu- and delta-opioid receptors, dimerization of the mu-specific morphine molecule was attempted, based on the hypothesis of the possible relationship between the molecular conformation of endogenous enkephalin and its selectivity for each opioid receptor. the nor2 ([normorphine]n-ch2-ch2-n[normorphine]) thus synthesized exhibited agonist activity showing a preference for binding with the delta-opioid receptor, compared with the parent morphin ...	1990	2164938
[antibiotic resistance of shigella isolated in the kara-kalpak a.s.s.r. 1987-1988].	sensitivity of shigella spp. isolated in one of the hospitals of nukus within 1987-1988 and earlier in 1977 and 1985 was studied. s. flexneri 1-5 remained the main causative agents of dysentery on the territory. however, beginning from 1987 there were registered cases of dysentery caused by s. dysenteriae 1. the isolates were most sensitive to cefotaxime, cephaloridine, polymyxin b and gentamicin. the majority of the isolates were resistant to tetracycline, levomycetin (chloramphenicol) and stre ...	1990	2144726
effects of chronic non-ketotic diabetes and aging on myocardial function and fatty acid oxidation.	the effects of aging and chronic non-ketotic diabetes on contractile properties, oxygen consumption, palmitate oxidation and morphology were studied in isolated, perfused working hearts of 2, 9, 12 and 22 month old rats. the heart rate, coronary flow, and oxygen consumption were no different among the 9, 12 and 22 month control and diabetic hearts. cardiac work was not depressed in control hearts until 22 months of age. depression of cardiac output due to aging in the control hearts progressed i ...	1990	2141842
[health economics--stopgap measures are no decisions. interview by kaj nyman].		2006	2095080
molecular analysis of strains of shigella boydii isolated in northern and southern italy.	in the years 1981-1988, shigella boydii played a very limited role in the aetiology of diarrhoeal disease in italy. however, between september and november, 1985, 19 isolates of serotype 2 were recovered in northern italy from a dysentery outbreak which occurred in a geriatrics hospital in abbiategrasso (milan, lombardy) and seven were identified in southern italy during the period january-july, 1986 from apparently unrelated infection cases occurring in brindisi (apulia). these isolates were co ...	1990	2092367
palindromic unit highly repetitive dna sequences exhibit species specificity within enterobacteriaceae.	palindromic units (pu, or rep for repetitive extragenic palindrome) constitute a family of dna sequences of 40 nucleotides which is highly repeated in the genome of escherichia coli. we analysed the presence of pu sequences in 99 different bacterial genomes by cross-hybridization. when pu sequences were used as a probe, only dna from enterobacteriaceae closely related to e. coli exhibited an appreciable hybridization signal: shigella sonnei, shigella boydii, salmonella enteritica serotype typhim ...	1990	2092362
[clinico-morphological comparisons in different types of dysentery].	clinical evidence and morphological picture of rectal biopsy specimens were analysed for 125 dysentery patients. as compared to a light course, moderately severe and severe dysentery presented enhanced microbial adherence and an elevated level of large lymphocytes in the external epithelium of the rectum, deeper penetration of shigella into crypts. on day 9-15 of the disease in attenuation of the clinical symptoms in severe and moderately dysentery morphological shifts persisted whereas the ligh ...	1990	2084341
[shigellosis].		1990	2076763
[recurrent thromboembolism disclosing protein c deficiency. apropos of a case with familial investigation].	every thromboembolic manifestation, especially in young subjects, calls for an aetiological study in which haemostasis is evaluated primarily with assays of physiological coagulation inhibitors: protein c, protein s and antithrombin iii. protein c deficiency is found in 6 to 7% of thromboembolic manifestations. we report the case of a 21-year old man who had phlebitis followed by pulmonary embolism without facilitating factors. protein c level was 50% of normal value (0.50 iu/ml). the patient re ...	1990	2075365
[problem of clinico-roentgenological diagnosis of acute pneumonia in infants in their first few months of life].	studies into the problems of diagnosing pneumonia in children of the first months of life carried out for many years have shown that pneumonia may be referred to the diseases with indefinite diagnostic criteria. in view of this fact the x-raying of the chest should be regarded as a method of varifying the diagnosis of pneumonia. the roentgenographic findings should be estimated bearing in mind the presence or lack of a syndrome such as bronchial obstruction and the epidemiological anamnesis data ...	2007	2075041
nonsquamous tumors of the head and neck in the geriatric population.	thyroid tumors, salivary gland tumors, and non-hodgkin's lymphoma are described. psychosocial issues involving the geriatric patient are discussed. case reports of a number of geriatric tumor patients are included.	2007	2074986
[directions of an ethic in genetic engineering: evaluation of an ethic for biotechnology].	a fundamentalistic point of view is for the evaluation of genetic engineering inadequate. using ethics to evaluate the consequences is not valid for gene transfers across species as a morally relevant criterion but is rather the assessment of toxic, pathogenic, and ecological effects of transgenic organisms. a criterion for human genetics is not the inviolability of the human embryo, but social and human tolerance and the consent of the affected.	1990	2074899
site-specific recombinase genes in three shigella subgroups and nucleotide sequences of a pinb gene and an invertible b segment from shigella boydii.	inversional switching systems in procaryotes are composed of an invertible dna segment and a site-specific recombinase gene adjacent to or contained in the segment. four related but functionally distinct systems have previously been characterized in detail: the salmonella typhimurium h segment-hin gene (h-hin), phage mu g-gin, phage p1 c-cin, and escherichia coli e14 p-pin. in this article we report the isolation and characterization of three new recombinase genes: pinb, pind, and defective pinf ...	1991	2061288
a weak adaptive response to alkylation damage in salmonella typhimurium.	an efficient adaptive response to alkylation damage was observed in several enterobacterial species, including klebsiella aerogenes, shigella sonnei, shigella boydii, escherichia alkalescens, escherichia hermanii, and escherichia fergusonii. increased o6-methylguanine-dna and methylphosphotriester-dna methyltransferase activities correlated with the induction of a 39-kda protein recognized by monoclonal antibodies raised against the escherichia coli ada protein. induced methyltransferase activit ...	1991	2050626
four decades of shigellosis in israel: epidemiology of a growing public health problem.	despite the improved standard of living in israel, shigellosis remains a common disease. examination of trends in the incidence of shigellosis in israel between 1951 and 1987 showed a period of declining rates followed by an increase in the reported incidence beginning around 1969. this increase was mainly due to shigella sonnei; rates of infection with shigella flexneri remained relatively constant. trends showed marked differences between age groups and between ethnic groups. in comparison, th ...	1991	2041956
pathogenicity of foodborne salmonella.	salmonella remains a leading etiological agent in bacterial foodborne diseases. although human salmonellosis generally presents as a self-limiting episode of enterocolitis, the disease can degenerate into chronic and debilitating conditions. antibiotic treatment of uncomplicated salmonellosis is contra-indicated because it tends to prolong the carrier state. clinical management of systemic infections with newer drugs such as third-generation cephalosporins and quinolones is most promising, parti ...	1991	2018704
inhibition by anti-cd2 monoclonal antibodies of anti-cd3-induced t cell-dependent b cell activation.	anti-cd3 mab can activate t cells to help in b cell activation as detected by late events, such as maturation of b cells into ig-secreting cells (igsc), or by early events, such as b cell surface expression of the activation marker cd23. two different anti-cd2 mab each inhibited anti-cd3-induced t cell-dependent b cell activation in a dose-dependent fashion. neither irradiation of the t cells prior to culture nor depletion of cd8+ cells abrogated the inhibitory effects of anti-cd2 mab. despite t ...	2007	1976440
esophageal function and dysfunction.		2007	1951923
a new role for radiologists in the development of cardiac surgery.		2007	1950902
reactive modifications of the autonomous time structure in the human organism.	the spectrum of biological rhythms exhibits characteristic principles of biological time structure which also rule the functional behaviour. with increasing period lengths the rhythms become increasingly complex. in the long-wave section the rhythmic functions find their corresponding cycles in the environment, whereas the shorter waves represent only endogenous autonomous rhythms, which maintain an internal time order by means of frequency- and phase-coordination. under resting conditions and i ...	1991	1932773
[mr tomography of aneurysmal bone cyst].	the preoperative findings of magnetic resonance imaging (mri) in six histology-proven aneurysmal bone cysts (abc) are examined and compared with previous publications concerning mri of abc. the signal intensities differ considerably, and not all of our cases conform with the literature data. they can be summarised in three different subheadings: one form that is very inhomogeneous in t1- and t2-weighting, with fluid-fluid levels in the cystic spaces; one intermediate form without fluid-fluid lev ...	2007	1932722
[the effect of tetracycline and vitamin e on energy metabolism in cardiac mitochondria of old rabbits pretreated with isoproterenol].	the possibility of eliminating adverse effects of tetracycline and isoproterenol pretreatment on energy generation of myocardial mitochondria by vitamin e administration was investigated in old rabbits. vitamin e administered in doses of 1.5 mg per kg body weight over 6 days was found to improve energy metabolism in old rabbits whose metabolism had been deranged by isoproterenol pretreatment in the dose of 1.5 mg per kg body weight. subsequent administration of vitamin e to rabbits pretreated wi ...	1991	1913199
["masked" autoantibodies from the serum of healthy blood donors cross-reacting with dna and bacterial lipopolysaccharides].	the "masked" autoantibodies with polyspecific activity were found in the serum of healthy donors. it is shown that these antibodies are able to react with antigens after the ion exchange chromatography with qae-sephadex. it was found that these "masked" antibodies are able to cross-react with dna and lipopolysaccharides of wide-spread species of bacteria. the possible role of these antibodies as in protection of organism from the external antigens as in the origin of autoimmune diseases is discu ...	1991	1908720
simultaneous infection with multiple serotypes of shigellae in a patient.	we isolated three different serotypes of shigella on admission from a patient with dysentery as well as a shigella-like organism and campylobacter jejuni upon follow-up. the patient produced serum antibodies to all three serotypes of shigellae.	1991	1889185
in the aftermath: health care in kuwait city.		2007	1865865
replantation in children.	the authors have replanted 162 parts in 120 children over the past 15 years. the youngest patient, undergoing successful replantation, was aged 7 months, 3 weeks. unlike an adult, any child suffering a traumatic amputation should be considered for a possible replantation. replantation should consist of minimal bone shortening to preserve epiphyseal plates, with repair of all severed structures. longitudinal k-wires usually provide adequate fixation. our survival rate for complete replantation in ...	2007	1865815
n-nitroso compounds, genotoxins and their precursors in gastric juice from humans with and without precancerous lesions of the stomach.	we are investigating the interrelationships between levels of total n-nitroso compounds (noc), genotoxic activity (both before and after nitrosation), degree of bacterial colonization in gastric juice and degree of severity or absence of precancerous lesions of the stomach. the mean level of constitutive total noc in gastric juice was similar in the different groups of patients, but it was higher in acidic gastric juice (n = 30) than in gastric juice at ph greater than 4.5 (n = 12). acid-catalys ...	2007	1855844
perfusion characteristics of hepatic cavernous hemangioma using intravenous ct angiography (ivcta).	thirty-three patients with 35 proven hepatic cavernous hemangiomas (hch) were studied with intravenous ct angiography (ivcta). 15 scans were performed during the first 30 s after bolus (6 ml/s) injection of 50 ml iodinated contrast material. thereafter 2 scans/min were obtained up to 30 min. three criteria were utilized at ivcta to make a specific diagnosis of hch: (1) detection of an intense mural nodular enhancement in the arterial phase. the density in the nodular region(s) should have a dens ...	2007	1855518
olfactory dysfunction in parkinson's disease.	an olfactory function test in 18 patients with parkinson's disease (pd) and 10 age-matched control subjects was performed. both detection and recognition thresholds were measured with five kinds of synthesized odorants (t & t olfactometry). before each test, rhinoscopic inspections were performed to exclude subjects who could have respiratory hyposmia. both detection and recognition thresholds in patients with pd were significantly elevated in comparison with those of control subjects. auditory ...	2007	1852411
absence of na+,k(+)-atpase regulation of endosomal acidification in k562 erythroleukemia cells. analysis via inhibition of transferrin recycling by low temperatures.	transferrin (tf) acidification has been shown to be limited to ph 6 in murine balb/c 3t3 fibroblasts, human a549 epidermoid carcinoma cells, and chinese hamster ovary cells and is followed by alkalinization during recycling. in contrast, tf acidification in the human erythroleukemic cell line k562 proceeds to below ph 5.5, and alkalinization of internal tf during recycling is not observed. to explore the regulation of endosomal ph in k562 cells, we determined whether the existence of an early en ...	1991	1847374
molecular epidemiology of shigella infections: plasmid profiles, serotype correlation, and restriction endonuclease analysis.	plasmid isolation was used to refine the epidemiologic analysis for 168 shigellosis cases in pima county, ariz. plasmids of less than 20 kb were used for comparison of plasmid profiles. plasmid patterns for each species were distinct. a total of 57 of 74 (77%) shigella flexneri strains could be placed into seven plasmid patterns, 70 of 79 (89%) shigella sonnei strains could be placed into seven patterns, 12 shigella boydii strains could be placed into six patterns, and each of 3 shigella dysente ...	1991	1847148
[the functional status of the endocrine pancreas in patients with acute intestinal infections].	ria was used to measure the content of insulin, c-peptide and glucagon in blood plasma of 84 patients with acute dysentery and food toxicoinfections. the studies were carried out in the acute disease period and before the discharge from hospital. the data obtained indicate that despite the appreciable differences in the disease pathogenesis, the pathophysiological mechanisms influencing pancreatic function are similar in many respects. the changes are characterized by an increase in plasma insul ...	1991	1810055
[the structure and absolute configuration of isorupestonic acid from artemisia rupestris l].	a new sesquiterpene compound named isorupestonic acid was isolated from artemisia rupestris and its absolute stereostructure was elucidated as 3b by spectral and x-ray crystallographic methods. interestingly, the isorupestonic acid is based upon an unusual 6, 7 membered ring skeleton differing from the 5, 7 membered ring rupestonic acid although both have the same absolute configuration at c-1. the biogenesis of isorupestonic acid most likely involves breaking the c4-c5 bond of rupestonic skelet ...	2007	1805508
serotype distribution and antimicrobial resistance of shigella isolates in singapore.	serogrouping of 506 shigella strains isolated in singapore from 1986 to 1990 showed that shigella flexneri (60.3%) was the most common, followed by s. sonnei (33.6%), s. boydii (3.2%) and s. dysenteriae (3%). of the 23 shigella serotypes identified, the predominant ones were s. flexneri types 2a and 1b, s. boydii types 1 and 5, and s. dysenteriae types 1 and 3. more than 80% of the shigella species were resistant to at least one antimicrobial drug, and the incidence of multiresistance was partic ...	1991	1800565
furosemide inhibits the centrally-mediated pressor response to clonidine in conscious, normotensive rats.	1. the effect of furosemide on the pressor response induced by intracerebroventricular (i.c.v.) injection of clonidine was investigated in freely moving, normotensive rats with chronically implanted arterial catheters. 2. when injected i.c.v., clonidine at doses of 5 and 10 micrograms produced a dose-dependent pressor response and a decrease in heart rate. no depressor response was induced by clonidine. 3. systemic (i.v.) pretreatment with furosemide (2-10 mg kg-1) increased urine volume and dos ...	1991	1797326
transcatheter management of pseudoaneurysms complicating pancreatitis.	hemorrhage from rupture of an arterial pseudoaneurysm is a potentially fatal complication of pancreatitis. seventeen patients underwent transcatheter embolization of 23 arteries for the treatment of 20 arterial pseudoaneurysms secondary to pancreatitis. their records were reviewed retrospectively to evaluate the clinical benefit of transcatheter therapy. at presentation, 15 of the 17 patients had gastrointestinal, intrasplenic, retroperitoneal, intraperitoneal, or postoperative wound bleeding. t ...	2006	1797219
transcatheter management of pseudoaneurysms complicating pancreatitis.	hemorrhage from rupture of an arterial pseudoaneurysm is a potentially fatal complication of pancreatitis. seventeen patients underwent transcatheter embolization of 23 arteries for the treatment of 20 arterial pseudoaneurysms secondary to pancreatitis. their records were reviewed retrospectively to evaluate the clinical benefit of transcatheter therapy. at presentation, 15 of the 17 patients had gastrointestinal, intrasplenic, retroperitoneal, intraperitoneal, or postoperative wound bleeding. t ...	2006	1797219
on the regulation of collagen-fibril shape and form.		2006	1794563
[continuous noninvasive recording of circulatory parameters while performing the valsalva test under elevated ambient pressure].	the results are presented which confirm applicability of the valsalva test as a functional exercise for the cardiovascular system while studying changes of the circulation regulation under high ambient pressure. methods of transthoracic tetrapolar impedance plethysmography, electro- and intervalocardiography and mean arterial pressure measurement by means of the oscillometric servosystem are shown as adequate and highly informative under these conditions.	2005	1790814
development of an in vitro microtest to assess drug susceptibility of babesia bovis and babesia bigemina.	continuous cultivation of the bovine hemoparasites babesia bovis and babesia bigemina was developed as an in vitro microtest to assess parasite susceptibility to babesicidal compounds. reproducibility of parasite multiplication rates was independent of culture size, making it possible to use a microscale of 100 microliters for each test sample. inhibitory concentrations (ic50s) of a commonly used babesicide, quinuronium sulfate, evaluated by this in vitro method were found to be 5 x 10(-8) g/ml ...	1991	1779305
[case study reports, no. 181 (society for scientific nursing)].		2006	1764935
plasmid-associated resistance to pivmecillinam in shigella flexneri and shigella boydii.		1991	1761454
antimicrobial resistance trends of shigellae isolates from calabar, nigeria.	during a 3-year study (january 1986-december 1988), stools of 2200 diarrhoeal or dysenteric patients were examined by culturing and 108 (4.9%) were found positive for shigellae. shigella flexneri was the commonest species isolated (54.6%), followed by sh. dysenteriae (24.1%). patients aged less than or equal to 15 years accounted for 51.4% of cases. shigellae over the 3 years showed high and sometimes rising resistance to ampicillin, chloramphenicol, streptomycin and cotrimoxazole and complete r ...	1991	1758013
contact-haemolysin production by entero-invasive escherichia coli and shigellae.	entero-invasive escherichia coli (eiec) and shigellae were tested for contact-haemolysin (ch) with red blood cells (rbcs) of guinea-pig, rabbit, rat, mouse, monkey, man, sheep and chicken; all bacteria showed the best lysis with guinea-pig rbcs. the best culture medium for ch activity of shigellae was tryptic soy broth, and for eiec it was casamino acid-yeast extract broth with 1 mm cacl2. ch production by all species was best at the slightly alkaline ph which is optimal for growth; it was also ...	1991	1753390
possible mechanisms underlying the slow lactose fermentation phenotype in shigella spp.	a southern hybridization analysis revealed that the region homologous to escherichia coli lacz was present on the chromosomal dnas of beta-galactosidase-positive shigella strains, such as shigella dysenteriae serovar 1 and shigella sonnei strains, whereas this region was absent from chromosomal dnas of beta-galactosidase-negative strains of shigella flexneri and shigella boydii. we found that the lacy-a region was deficient in s. dysenteriae serovar 1 and believe that this is the reason for the ...	1991	1746953
relatedness of o-specific lipopolysaccharide side chain genes from strains of shigella boydii type 12 belonging to two clonal groups and from escherichia coli o7:k1.	the o-specific lipopolysaccharide side chains of escherichia coli o7 and shigella boydii type 12 possess similar but not identical chemical structures. we investigated the genetic relatedness between the o-specific side chain genes in members of these two species. examination of outer membrane protein and lipopolysaccharide (lps) banding patterns demonstrated that five strains which had been identified as s. boydii type 12 fell into two clonal groups, sb1 and sb2. hybridizations with o7-specific ...	1991	1718868
[antigenic polysaccharides of shigella bacteria. structure of the polysaccharide chain of the lipopolysaccharide from shigella boydii, type 11].	on mild acid degradation of the shigella boydii, type 11 lipopolysaccharide, the corresponding o-specific polysaccharide composed of d-glucuronic acid, 2-acetylamino-2-deoxy-d-glucose, d-ribose and l-rhamnose residues in the ratio 1:1:1:3 was obtained. methylation, partial acid hydrolysis and 13c-nmr spectral data for the polysaccharide led to the structure of the oligosaccharide repeating unit as a branched hexasaccharide: [formula: see text]. numerous o-acetyl groups attached non-stoichiometri ...	1991	1712200
characterization of shigella dysenteriae serotypes 11, 12, and 13.	we conducted serologic and biochemical studies on strains of three provisional shigella serotypes. included were 19 strains of serotype 3873-50 from three countries (1 from mexico, 1 from netherlands antilles, and 17 from the united states), 13 strains of serotype 3341-55 from three countries (1 from canada, 1 from bulgaria, and 11 from the united states), and 19 strains of serotype 19809-73 from two countries (16 from israel and 3 from the united states). reactions of these strains with homolog ...	1990	1701447
conduction velocity distribution of afferent fibers innervating the rat urinary bladder.	the conduction velocities of individual afferent fibers innervating the rat urinary bladder were determined by the antidromic stimulation of dorsal roots while recording from bladder postganglionic nerves. conduction velocities ranged from 0.5 to 21.0 m/s; 70% of the velocities were less than 2.5 m/s. the distribution within the dorsal roots was ipsilateral with 84% in l6 and 16% in s1. neuroanatomical tracing with horseradish peroxidase applied to individual bladder postganglionic nerves result ...	1990	1698508
decreased monocyte-induced angiogenesis in scleroderma.		2006	1698391
transient cytokeratin expression in skeletal muscle during murine embryogenesis.	cytokeratin expression was investigated in paravertebral skeletal musculature of 10 d and 18 d old embryos as well as in adult nmri-mice. the muscular nature of the evaluated tissue was evidenced by their expression of vimentin and desmin. binding moieties for cytokeratin antibodies (polyclonal and monoclonal) could be demonstrated only in muscle cells of 10 d old embryos. concerning subtypes, the mouse equivalents of the human cytokeratins nos. 8, 18 and 19 could be made probable. the importanc ...	1990	1698345
monoclonal antibodies to quebec strain (q17) of bovine rotavirus.	fourteen monoclonal antibodies (mabs) against "quebec" strain (q17) of bovine rotavirus were isolated and characterized. four were specific for viral protein vp7 and ten were specific for viral protein vp6. five different isotypes were represented by this group of antibodies. all of the anti-vp6 and none of the anti-vp7 antibodies were sensitive to the effects of periodate on their antigen. the antibodies could be separated into three groups based on their relative resistance to the dissociation ...	1990	1698323
molecular epidemiology of trimethoprim-resistant shigella boydii serotype 2 strains from bulgaria.	in 1990 an increased number of strains of shigella boydii serotype 2 were isolated from different regions of bulgaria. strains were reported as sporadic, although they showed identical phenotypic characteristics, including resistance to ampicillin, carbenicillin, streptomycin, sulfonamide, tetracycline, ticarcillin, and trimethoprim. the objective of this study was to determine the genetic relatedness of the strains and the mechanism of their antimicrobial resistance. plasmid fingerprinting show ...	1992	1624559
[obesity. various aspects in daily practice].	overweight and obesity are the most often encountered disease conditions in general practice. recent evidence of the importance of fat distribution is discussed. the basic therapeutic approach for the most effective therapy of obesity is probably the combination of a dietary (hypocaloric), a behavioral and a physical activity approach. in this general overview the physiologic background of abdominal obesity and some selected therapeutic implications are discussed.	2006	1594849
estimating the probability of spontaneous abortion in the presence of induced abortion and vice versa.	an integrated approach to estimate the total number of pregnancies that begin in a population during one calendar year and the probability of spontaneous abortion is described. this includes an indirect estimate of the number of pregnancies that result in spontaneous abortions. the method simultaneously takes into account the proportion of induced abortions that are censored by spontaneous abortions and vice versa in order to estimate the true annual number of spontaneous and induced abortions f ...	2006	1594736
copulatory analgesia in male rats ensues from arousal, motor activity, and genital stimulation: blockage by manipulation and restraint.	the effect of copulation on the vocalization threshold to tail shock (vtts) was assessed in freely-moving, sexually experienced, wistar male rats. mean vtts during the first copulation was 40% above the baseline values and slightly decreased during the first postejaculatory interval (pei; 28% above baseline). vtts mean values further increased during the second copulatory series (93% above baseline and 63% during the pei). testing at the same intervals in noncopulating rats did not induce analge ...	1992	1594675
acamprosate modulates synaptosomal gaba transmission in chronically alcoholised rats.	male sprague-dawley rats were pulmonary alcoholised for 30 days. six were treated with acamprosate (400 mg/kg/day, po) during alcoholisation. the control nonalcoholised group also received acamprosate (400 mg/kg/day, po) during the 30 days. at the end of the experiment, brains areas (cortex, hippocampus, thalamus, striatum, and olfactory bulbs) were dissected for the study of synaptosomal 3h-gaba uptake. in another experiment, gaba levels were determined in the same areas using hplc with electro ...	1992	1594633
identification and analysis of the gene encoding human pc2, a prohormone convertase expressed in neuroendocrine tissues.	in recent studies we have identified pc2 and pc3, members of a family of serine proteases that are related structurally to subtilisin, and have provided evidence that these are involved in the tissue-specific processing of prohormones and neuropeptides. pc2 is expressed at high levels in the islets of langerhans, where it participates in the processing of proinsulin to insulin (s.p.s. and d.f.s., unpublished data). to evaluate the regulated expression of the human pc2 (hpc2) gene we have analyze ...	1992	1594602
characterization of aeromonas caviae antigens which cross-react with shigella boydii 5.	live and boiled cells of 16 strains of aeromonas caviae, isolated from patients with diarrhea, agglutinated with shigella boydii 5 antiserum in a slide test. further studies with seven selected strains showed agglutination with boiled cells in a tube test. lipopolysaccharide antigen extracted from one of these strains cross-reacted with s. boydii 5 in enzyme-linked immunosorbent assay and immunoblot studies. either all or the majority of the seven strains possessed properties deemed to be diarrh ...	1992	1583145
bioactive polymers: in vitro and in vivo study of controlled release neomycin.	neomycin is coupled on xanthan-a polysaccharide of microbial biosynthesis produced by xanthomonas campestris-through ionic complexation. the kinetics of neomycin release, in vitro, at ph = 8.2 is studied. a controlled release of neomycin, following a zero order kinetics is observed, regardless of the eluent flow. neomycin complexed on xanthan, administered in a unique daily dose to patients suffering from dysentery in the 100 cases taken in study, has shown a high clinical efficiency as compared ...	1992	1573555
drug resistance and plasmid profile of shigellae in taiwan.	one hundred and twenty-eight shigella strains isolated from newborn and infant human faecal specimens at kaohsiung medical college hospital in taiwan were serogrouped, serotyped and examined for drug-resistance patterns and for the presence of plasmids. forty-seven per cent of the isolates were found to belong to the shigella sonnei serogroup, 41% to the s. flexneri group, 9% to the s. boydii group and 3% to the s. dysenteriae group. the serotype with the greatest number of strains was s. sonnei ...	1992	1547844
[major hypereosinophilia disclosing colonic cancer].		2006	1533927
asbestos: the turbulent interface between science and policy.		2006	1489439
[bacillary dysentery--1990].		1992	1475396
[the theoretical and practical interpretations of the basic manifestations of the epidemic process in shigellosis].		1992	1466177
[the etiological structure of shigellosis in the former ussr--an indicator of the activity of the main routes of infection transmission].	the data on the etiological structure of shigella infections in the ussr in 1988-1989 are presented. the study showed the dominating role of s. flexneri with s. sonnei also retaining great importance in shigella infections. the process of the liquidation of s. dysenteriae and s. boydii infections began in some large cities. the domination of dysentery caused by s. flexneri and a high typhoid rate, particularly in central asia, were due to poor water supply of the population. the spread of dysent ...	1992	1455964
shigellosis in children: a prospective hospital based study.	from 1985 to 1988, fecal samples of 950 hospitalized children suffering from diarrhea or dysentery were screened for shigella species using standard methods. shigella species were isolated as sole pathogen from 192 (20.2%) cases and s. flexneri type 2 was the predominant serotype. shigella infection was prevalent throughout the year with high isolation rate during the summer and early monsoon months. shigella strains isolated during the period were resistant to most of the commonly used drugs fo ...	1992	1452309
concentration of milk secretory immunoglobulin a against shigella virulence plasmid-associated antigens as a predictor of symptom status in shigella-infected breast-fed infants.	we conducted a prospective, community-based study of healthy breast-fed mexican infants to determine the protective effects of anti-shigella secretory iga antibodies in milk. milk samples were collected monthly, and stool culture specimens were obtained weekly and at the time of episodes of diarrhea. nineteen breast-fed infants were found to have shigella flexneri, shigella boydii, or shigella sonnei in stool samples. ages of the 10 infants with symptomatic infection and the nine with asymptomat ...	1992	1447644
health checks on patients 75 years and over in nottinghamshire after the new gp contract.	to investigate annual health checks for patients of 75 years and over required by the 1990 contract for general practitioners.	2006	1393076
the vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies.	angiogenesis plays critical roles in organ development during embryonic and fetal life, wound healing and in a variety of pathological conditions. vascular endothelial growth factor (vegf) is a secreted growth factor specific for vascular endothelial cells which induces angiogenesis in vivo. to gain a better understanding of the physiological role of vegf, we have generated and characterized four murine monoclonal antibodies (mabs) using the 165 amino acid species of recombinant human vegf as im ...	1992	1380254
[lipid and mineral metabolism and morbidity with temporary loss of work capacity in miners].	examination is performed on 87 miners from mine for copper production subject to intensive local vibrations with average rate of increase (k) of the norms for the individual octave frequencies 2.4 times for 3 h exposure of the working shift, as well as to intensive noise--113-115 db/a equivalent level, general dust--23 mg/m3, fine dust--3.5 mg/m3 and fine quartz--0.43 mg/m3. there are data for vibration effect--changes in the cold test, vibration sensoriness, ultra sound sonometry, in all miners ...	2005	1364539
sexual transmission of htlv infections in southern india.		1992	1346809
[bacteriology of shigella isolated in a tropical zone chu].	from 1981 to 1991, five hundred eighty one shigella's strains were isolated in the laboratories of the chu fann of dakar. they represent 24.8 per cent of enteropathogen agents and 4.3 per cent of diarrhoeae causative agents. shigella flexneri was predominant (71%), following by shigella dysenteriae (14.5%), shigella sonnei (11.4%) and shigella boydii (2.5%). in pediatric hospital 90 per cent of strains were isolated between 1 and 5 years age; in adults, the pic was found from 20 to 30 years. fiv ...	1992	1345084
neonatal tetanus: a developmental follow-up study.		2005	1278947
editorial: who owns your medical records?		2005	1262726
circadian properties of the rhythmic system in individual nucleated and enucleated cells of acetabularia mediterranea.		2005	1248525
the forgotten treatment modality in bipolar illness: psychotherapy.	the author presents 31 bipolar patients treated with combined lithium prophylaxis and psychotherapy for up to 41 months. the grave prognosis of untreated bipolar illness is reviewed. the improved prognosis with lithium prophylaxis alone is reviewed. the author demonstrates an improved prognosis when lithium prophylaxis is combined with psychotherapy and discusses his findings as to why lithium prophylaxis alone still predicts a grave outcome.	2005	1183307
effect of plasma protein binding on elimination of bilirubin.		1975	1151726
[antigenic relationships between "levinea amalonatica" and "shigella dysenteriae" and "boydii" (author's transl)].	twenty-eight strains among thirty-five levinea amalonatica show o antigenic relationships with shigella as follows: with s. dysenteriae 3 (5 strains), s. dysenteriae 4 (1 strain), s. dysenteriae 5 (3 strains), s. dysenteriae 7 (11 strains), s. boydii 6 (7 strains), and with both s. boydii 15 and s. dysenteriae 8 (1 strain). these strains do not induce purulent keratogenous conjunctivitis in guinea pigs as shigella do.	1975	1098541
shigella strains associated with infantile diarrhea in the kaohsiung area.	in 1969 and 1974, 375 shigella strains were isolated in the kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. in 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. the isolation rates were higher in may (21.2%), october (20.8%), april (20.6%), august (19.7), november (18.8%) and january (18.5%), than in o ...	1975	1097211
superiority of macconkey's agar over salmonella-shigella agar for isolation of shigella dysenteriae type 1.	the efficiency of macconkey's agar in the isolation of various types of shigella was compared with that of salmonella-shigella (ss) agar during an extensive 18-month outbreak of disease caused by shigella. in all, 1,580 isolates of shigella were obtained from 12,307 rectal swab and fecal samples of patients with diarrhea and their contacts by direct plating onto macconkey's and ss agars. shigella dysenteriae type 1 and shigella flexneri constituted 55 percent and 33 percent of all isolates, resp ...	1975	1094073