Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| in vitro processing of anthrax toxin protective antigen by recombinant pc1 (spc3) and bovine intermediate lobe secretory vesicle membranes. | protective antigen (pa), an 83-kda protein produced by bacillus anthracis, requires proteolytic activation at a tetrabasic site (rkkr167) before it can combine with either edema factor or lethal factor on the cell surface. the complex is then endocytosed and the target cell intoxicated. previous work has demonstrated that furin, a ubiquitously distributed, subtilisin-like protease, can perform this cleavage. in this study, another member of the furin family, pc1 (spc3), was tested as a putative ... | 1995 | 7840657 |
| characterization of the bacillus anthracis s-layer: cloning and sequencing of the structural gene. | bacillus anthracis, a gram-positive, spore-forming bacterium, is the etiological agent of anthrax. the gene coding for the s-layer protein (sap) was cloned on two contiguous fragments in escherichia coli, and the complete sequence of the structural gene was determined. the protein, sap, is composed of 814 residues, including a classical prokaryotic 29-amino-acid signal peptide. the mature form has a calculated molecular mass of 83.7 kda and a molecular mass of 94 kda on a sodium dodecyl sulfate- ... | 1995 | 7836294 |
| [a case of the cutaneous form of anthrax]. | 1994 | 7831895 | |
| the transformation frequency of plasmids into bacillus anthracis is affected by adenine methylation. | plasmids pltv1 and phv33, capable of replicating in both gram+ and gram- bacterial hosts (shuttle vectors), when derived from the escherichia coli strain hb101, were inactive in an electro-transformation assay employing the bacillus anthracis strains delta ames-1 and delta v1b-1 as recipients. the same plasmids isolated from the dna methyltransferase (mtase)-deficient e. coli strain gm2929 (dam, dcm), were able to transform the b. anthracis strains at a frequency of 10(2)-10(3) transformants/mic ... | 1995 | 7828932 |
| identification and characterization of a trans-activator involved in the regulation of encapsulation by bacillus anthracis. | production of the plasmid-pxo2-encoded capsule by bacillus anthracis is required for full virulence of the organism. the induction of capsule synthesis in vitro requires growth in the presence of bicarbonate and co2; however, little else is known about the regulation of capsule synthesis and the role it plays in the expression of virulence. recently, transposon tn917 mutagenesis of b. anthracis plasmid pxo2 identified genes involved in capsule production and genes associated with virulence in in ... | 1995 | 7828912 |
| proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases. | before intoxication can occur, anthrax toxin protective antigen (pa), pseudomonas exotoxin a (pe), and diphtheria toxin (dt) must be activated by proteolytic cleavage at specific amino acid sequences. previously, it was shown that pa and dt can be activated by furin. in chinese hamster ovary (cho) cells, wild-type (rkkr) and cleavage site mutants of pa, each administered with a modified form of anthrax toxin lethal factor (the n terminus of lethal factor fused to pe domain iii), had the followin ... | 1995 | 7806387 |
| live bacterial vaccines for animals. | 1995 | 7796957 | |
| pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein. | the alpha 2-macroglobulin (alpha 2m) receptor/low-density lipoprotein receptor-related protein (lrp) is important for the clearance of proteases, protease-inhibitor complexes, and various ligands associated with lipid metabolism. while the regulation of receptor function is poorly understood, the addition of high concentrations of the 39-kd receptor-associated protein (rap) to cells inhibits the binding and/or uptake of many of these ligands. previously, we (kounnas, m.z., r.e. morris, m.r. thom ... | 1995 | 7790352 |
| anthrax: from mesopotamia to molecular biology. | 1995 | 7784488 | |
| protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus. | the edema factor (ef) and lethal factor (lf) components of anthrax toxin require anthrax protective antigen (pa) for binding and entry into mammalian cells. after internalization by receptor-mediated endocytosis, pa facilitates the translocation of ef and lf across the membrane of an acidic intracellular compartment. to characterize the translocation process, we generated chimeric proteins composed of the pa recognition domain of lf (lfn; residues 1-255) fused to either the amino-terminus or the ... | 1995 | 7783638 |
| the ecology of anthrax spores: tough but not invincible. | bacillus anthracis is the causative agent of anthrax, a serious and often fatal disease of wild and domestic animals. central to the persistence of anthrax in an area is the ability of b. anthracis to form long-lasting, highly resistant spores. understanding the ecology of anthrax spores is essential if one hopes to control epidemics. studies on the ecology of anthrax have found a correlation between the disease and specific soil factors, such as alkaline ph, high moisture, and high organic cont ... | 1995 | 7773917 |
| evaluation of the biolog system for the identification of bacillus anthracis. | the potential of the biolog system for the identification of bacillus anthracis was evaluated. in-house generated databases allowed the correct identification of 19 of 20 isolates of b. anthracis within 24 h. five strains of the closely related b. cereus/thuringiensis group were misidentified as b. anthracis. for this reason the test could only serve as a primary screen with further testing being required to confirm identity. in addition 20% of all the strains of bacilli examined during the stud ... | 1995 | 7766114 |
| evaluation of bacillus subtilis strain is53 for the production of bacillus anthracis protective antigen. | an asporogenous strain of bacillus subtilis, is53, transformed with plasmid ppa102, produces the protective antigen (pa) component of the tripartite toxin of b. anthracis. addition of yeast extract was required to support growth and pa production in all the media examined. protective antigen expression was down-regulated during exponential growth and extracellular proteases caused marked degradation of the mature protein. | 1994 | 7765396 |
| differentiation of bacillus anthracis and other 'bacillus cereus group' bacteria using is231-derived sequences. | sequences based on the conserved 20 bp inverted repeat of is231 variants were used as polymerase chain reaction-based fingerprinting primers of the member species of the bacillus cereus group (b. anthracis, b. cereus, b. thuringiensis and b. mycoides), because of their close association with transposons, principally tn4430 in b. thuringiensis. fingerprints of b. anthracis were simple, and specifically allowed its identification and sub-differentiation from other members of the group. fingerprint ... | 1995 | 7750728 |
| the infection hazards of human cadavers. | cadavers may pose infection hazards to people who handle them. none of the organisms that caused mass death in the past--for example, plague, cholera, typhoid, tuberculosis, anthrax, smallpox--is likely to survive long in buried human remains. items such as mould spores or lead dust are much greater risks to those involved in exhumations. infectious conditions and pathogens in the recently deceased that present particular risks include tuberculosis, group a streptococcal infection, gastrointesti ... | 1995 | 7749455 |
| purification and characterization of the major surface array protein from the avirulent bacillus anthracis delta sterne-1. | many prokaryotic organisms possess surface layer (s-layer) proteins that are components of the outermost cell envelope. with immunogold labeling, it was demonstrated that the protein extractable antigen 1 (ea1) was localized on the outer surface and specifically to cell wall fragments from bacillus anthracis which retained the s layer. when grown in rich medium under aerobic conditions, the avirulent strain delta sterne-1 released large amounts of ea1 into the medium. this ea1 had no higher-orde ... | 1995 | 7730281 |
| a particular class of virulence factors: calmodulin-activated bacterial adenylate cyclases. | 1994 | 7696748 | |
| genetic variability of bacillus anthracis and related species. | we evaluated the abilities of pulsed-field gel electrophoresis (pfge) and sequences of intergenic spacer regions (isrs) between two highly conserved genes, 16s-23s rdna and gyrb-gyra isrs, to detect variation in strains of bacillus anthracis as well as two closely related species, b. cereus atcc 14579 and b. mycoides atcc 6462. for each restriction enzyme, (noti, sfii, and smai), the pfge banding patterns for three b. anthracis strains (ames, vollum, and sterne) were identical. however, closely ... | 1995 | 7665658 |
| intestinal anthrax in a two-year-old child. | 1995 | 7638018 | |
| [a case for diagnosis: anthrax of the eyelids]. | 1994 | 7632010 | |
| sensitive detection of biotoxoids and bacterial spores using an immunomagnetic electrochemiluminescence sensor. | extremely sensitive detection of various biotoxoids and bacterial spores using the commercial origen analyzer was achieved by capture on antibody-conjugated micron sized magnetic beads (mbs) followed by binding of ruthenium (ii) trisbipyridal chelate (ru(bpy)2+3-labelled reporter antibodies. immunomagnetically captured target materials were collected on a magnet. electrochemiluminescence (ecl) was evoked from the ru(bpy)3(2+)-tagged reporter antibodies by application of an electrical potential. ... | 1995 | 7612203 |
| a nested pcr method for the detection of bacillus anthracis in environmental samples collected from former tannery sites. | a nested pcr has been developed to detect bacillus anthracis spores in natural soil and waste samples which may be heavily contaminated by organic and inorganic compounds as is the case at former tannery sites. outer and inner pairs of primers were designed from the protective antigen gene of the plasmid px01 as well as from the genes b and c of the capsule region of the plasmid px02. the dna was prepared from an enrichment broth after killing the vegetative cells by h2o2 treatment. the method a ... | 1995 | 7600011 |
| guidelines for vaccination of horses. the american association of equine practitioners' vaccination guidelines subcommittee of the avma council on biologic and therapeutic agents. | 1995 | 7591939 | |
| [introduction to the commemorative session of the centennial of the death of louis pasteur]. | when elected a member of académie de médecine in 1873, pasteur was well known for his achievements in chemistry, fermentation and silk worm diseases. he denied spontaneity of diseases, their cause are living germs. passionate disputations took place in academy on subjects of septicaemia, childbirth fever, or fowl cholera. in 1881, his success was obtained by vaccination of sheep against epidemic anthrax: his method of virus action softening was available for many human infections diseases, in sp ... | 1995 | 7583455 |
| nasal anthrax in boston. | 1995 | 7568363 | |
| a case of anthrax septicaemia in a london teaching hospital. | 1995 | 7550591 | |
| effect of anthrax toxin's lethal factor on ion channels formed by the protective antigen. | protective antigen (pa), a component of anthrax toxin, mediates translocation of the toxin's lethal and edema factors (lf and ef, respectively) to the cytoplasm, via a pathway involving their release from an acidic intracellular compartment. pa63, a 63-kda proteolytic fragment of pa, can be induced to form ionconductive channels in the plasma membrane of mammalian cells by acidification of the medium. these channels are believed to be comprised of dodecyl sulfate-resistant oligomers (heptameric ... | 1995 | 7543106 |
| comparative analysis of the 16s to 23s ribosomal intergenic spacer sequences of bacillus thuringiensis strains and subspecies and of closely related species. | bacillus thuringiensis spacer regions between the 16s and 23s rrnas were amplified with conserved primers, designated 19-mer and 23-mer primers. a spacer region of 144 bp was determined for all of 6 b. thuringiensis strains, 7 b. thuringiensis subspecies, and 11 b. thuringiensis field isolates, as well as for the closely related species bacillus cereus and bacillus anthracis. computer analysis and alignment of nucleotide sequences identified three mutations and one deletion in the intergenic spa ... | 1995 | 7538281 |
| the channel formed in planar lipid bilayers by the protective antigen component of anthrax toxin. | anthrax toxin consists of three proteins: edema factor (ef, 89 kda), lethal factor (lf, 90 kda), and protective antigen (pa, 83 kda). the former two gain access to the cytosol, where they exert their respective toxic effects on a cell, only in binary combination with pa. the proposed pathways of ef and lf transport consists of (i) pa attaching to a membrane receptor; (ii) its proteolytic cleavage into two fragments, of which the larger, 63 kda piece (pa63) remains attached to the receptor; (iii) ... | 1994 | 7512762 |
| enzyme-linked immunosorbent assay using a recombinant baculovirus-expressed bacillus anthracis protective antigen (pa): measurement of human anti-pa antibodies. | we developed an antigen capture enzyme-linked immunosorbent assay (elisa) which does not require purified protective antigen (pa) for detection of human antibodies to bacillus anthracis pa. lysates of spodoptera frugiperda (sf-9) cells infected with recombinant baculovirus containing the pa gene were used as the source of pa to develop the elisa. recombinant pa from crude sf-9 cell lysates or pa purified from b. anthracis sterne strain was captured by an anti-pa monoclonal antibody coated onto m ... | 1994 | 7496927 |
| acting against anthrax. us military veterinarian helps haitians and their animals. | 1995 | 7493881 | |
| pathology of experimental inhalation anthrax in the rhesus monkey. | the inhalation form of anthrax, although rare, is nearly always fatal because of the rapid progression of the disease with little host response until the terminal stages of the disease. the gulf war heightened the concern that anthrax could be used as a biologic weapon. past studies modeling pathologic changes in human inhalation anthrax have used the rhesus monkey. | 1995 | 7474943 |
| [water as a vector of infection: waterborne bacteria (author's transl)]. | the cholera and typhoid epidemics caused by drinking water were still characterized, at the beginning of the century by a high rate of morbidity and lethality. in addition to these micro-organisms, there are yet other pathogens which find their way into the drinking water. therefore the pathogens causing infection and for which water can serve as a vector, are shown in a survey and for some of them their survival times in the various types of water are mentioned. the remedial measures which were ... | 1980 | 7456871 |
| [jet immunization with polyvalent vaccine against plague, tularemia, and anthrax]. | 1980 | 7445856 | |
| [case of recurrent human anthrax occurring several weeks after the primary disease]. | the carbuncle was located on the back of the right hand in the primary anthrax infection and on the lower third of the right leg in the secondary infection. in both cases the diagnosis of anthrax was confirmed bacteriologically and by the anthraxin test. the course of the secondary infection was less severe. the conclusion on the possibility for rare cases of anthrax recurring has been made. this fact may be important for the assessment of immunity. | 1980 | 7445847 |
| the effects of war on the control of diseases of livestock in rhodesia (zimbabwe). | the disruption of veterinary services in the tribal areas of rhodesia (now zimbabwe) during seven years of conflict resulted in serious epidemics of disease. the cessation of dipping was followed by the death of an estimated one million cattle from tick-borne disease. heavy mortality followed the disruption of control measures for trypanosomiasis. foot-and-mouth disease and anthrax spread widely in the tribal areas. rabies, normally restricted to areas bordering botswana and mocambique, became w ... | 1980 | 7445371 |
| death at sverdlovsk: a critical diagnosis. | 1980 | 7433972 | |
| [epidemiologic analysis of anthrax in sverdlovsk]. | 1980 | 7415678 | |
| anthrax in humans in zimbabwe. | 1980 | 7407895 | |
| anthrax and its transmission to humans. | 1980 | 7407891 | |
| reporting of zoonotic diseases. | departments of public health and agriculture in all 50 states of the united states and the district of columbia were queried in 1977 to determine which of some selected zoonoses are reportable, the method of reporting and the diagnostic stage at which reporting is required. fifty-three of the 62 diseases on the public health questionnaire were listed as reportable, with hepatitis a required by 49 of the 51 jurisdictions. telephone reporting was required in nearly 19% of the disease-jurisdiction ... | 1980 | 7395853 |
| transmission of anthrax. | 1980 | 7371075 | |
| [rare form of anthrax with a lesion of the lids of both eyes]. | 1980 | 7366166 | |
| an epizootic of anthrax in goats and sheep in danbatta nigeria. | 1981 | 7348590 | |
| [errors in diagnosing a case of anthrax]. | 1981 | 7345591 | |
| methods of quantitative microbiological analyses that support the diagnosis, treatment, and prognosis of human infection. | the microorganisms responsible for the production of an infection may be considered to be in two classes: classical microbes and host-defined microbes. classical microbes are those pathogens which fulfill the koch-henle postulates, and their isolation from a host indicates infection. they are not normally part of the body's normal flora, although they may be acquired by the host and enter into a passive relationship known as the carrier state. examples of this type of microbe are bacillus anthra ... | 1981 | 7273838 |
| anthrax meningitis in zimbabwe. | 1981 | 7261058 | |
| [anthrax meningitis: an ostensibly primary case]. | 1981 | 7232164 | |
| intestinal anthrax in man: a case report. | 1980 | 7214503 | |
| [outbreak of anthrax infections in human and domestic animals and the treatment of infectious foci in jiayu county]. | 1982 | 7185449 | |
| a major epidemic of anthrax in zimbabwe. | 1982 | 7168859 | |
| anthrax in infants and children in afghanistan. | 1982 | 7152595 | |
| communicable disease report. united kingdom--october to december 1981. | 1982 | 7140228 | |
| [anthrax of the eyelids]. | 1982 | 7132185 | |
| anthrax island. why worry? | 1982 | 7099248 | |
| [robert koch; man and work (author's transl)]. | the paper presents a brief survey of robert koch's brilliant achievement in medicine, with particular emphasis being placed on his discovery of the tubercle bacillus made known on 24th march, 1882, his information about the aetiology of anthrax in 1876, and the pathogens of wound infection (1878), as his most valuable contributions to medical research and practice. robert koch can truly be regarded as one of the great benefactors of mankind. he was a genius endowed with spiritual and practical a ... | 1982 | 7046286 |
| anthrax toxin. | 1981 | 7025030 | |
| virgil on anthrax. | 1981 | 7023266 | |
| inhalation anthrax. | 1980 | 7013615 | |
| anthrax. william smith greenfield, m.d., f.r.c.p., professor superintendent, the brown animal sanatory institution (1878-81). concerning the priority due to him for the production of the first vaccine against anthrax. | the purpose of this paper is to draw attention to the fact that w. s. greenfield, working at the brown animal sanatory institution in london, prepared an effective vaccine against anthrax and described his results some months before the experiment of pasteur at pouilly-le-fort. partly through lack of financial support and partly due to opposition by the antivivisectionists, greenfield was forced to confine his experiments to a small number of animals, but his results were nevertheless conclusive ... | 1980 | 7007487 |
| the value of animal models. | 1980 | 7006406 | |
| [anthrax in the differential diagnosis of surgical skin infections]. | 1980 | 6999823 | |
| [war and protection against epidemics]. | 1980 | 6998225 | |
| gram-positive pneumonias. | 1980 | 6993804 | |
| [rare form of anthrax]. | 1981 | 6974923 | |
| [dermatologic form of anthrax diagnosed at the dental clinic]. | 1980 | 6931659 | |
| case of anthrax meningitis survival. | 1981 | 6895865 | |
| [a review of 35 anthrax cases]. | of 35 cases diagnosed as anthrax during 1.9.1981 - 1.12.1982, 18 were females (51,4%) and 17 were males (48,6%), the mean age was 39,7. all of the women were housewives, 14 male patients were farmers, 1 was a tradesman, 1 a worker, and 1 a butcher. it was localised on the skin in 31 cases (88,6%) and in the throat in 4 cases (11,4%). penicillin was used for treatment. in one of the cases with throat localisation, sepsis developed, leading to death. | 1983 | 6888296 |
| a major epidemic of anthrax in zimbabwe. part ii. | 1983 | 6861201 | |
| [findings on the spread of anthrax spores in the provincial territory of milan with tanneries]. | this paper presents the results of a research, started since 1976, on the environmental spreading of the anthrax spores in the county of milan, where there is an high concentration of leather manufactures preparing and tanning skins mostly imported from africa. b. anthracis spores were found in the raw skins, in the sewage water from the tanning units and in the fresh and dry sludges from the tannery water treatment plants. we propose hereby few operational procedures for the sanitizing of the i ... | 1982 | 6821338 |
| [comparative study of three lysogenic systems for the testing of potential mutagens and carcinogens]. | 1982 | 6820616 | |
| [effect of specific vaccinal antigens and preparations on general resistance in growing experimental and domestic animals]. | studied was the effect of some viral and bacterial antigens as well as of a preparation obtained by filatov's method (modified by the author) on the general resistance in growing laboratory and domestic animals. it was found that in infantile albino mice the best protection against challenge with escherichia coli and pasteurella avicida was provided through the treatment with a biostimulator and a killed culture of a strongly proteolytic, unidentified strain of the 't3' bacterium. the vaccines a ... | 1982 | 6820584 |
| assessment of immunofluorescence measurements of individual bacteria in direct and indirect assays for bacillus anthracis and bacillus cereus spores. | 1982 | 6819288 | |
| [new immunofluorescent method for the rapid determination of microbial antibiotic sensitivity]. | a new procedure for rapid determination of the levels of antibiotic sensitivity in pathogenic microorganisms with the use of fluorescent antibodies is described. the procedure was developed with the use of a model of the vaccinal strains of bacillus anthracis. it is based on determination of the microbial antibiotic resistance with the method of serial dilutions on solid media. still, the medium with an antibiotic is inoculated instead of the pathogen with the native material subject to the anal ... | 1982 | 6816140 |
| anthrax-specific "ap 50-like" phages isolated from bacillus cereus strains. | phages exerting a specific action on bacillus anthracis were isolated from mitomycin c-induced concentrated lysates of 5 bacillus cereus strains producing megacin a (phospholipase a). in electron micrographs the phages closely resembled the anthrax-specific, lipid containing phage ap 50 isolated earlier from soil sample. the phages were similar to ap 50 also in their antigenic and chemical structure, host range and sensitivity to organic solvents, detergents and caesium chloride. the dna charact ... | 1982 | 6814198 |
| new method for differentiating members of the bacillus cereus group: collaborative study. | a collaborative study was conducted of a new method for differentiating members of the bacillus cereus group. using the new method, each of 14 collaborators identified 8 bacillus cultures, which represented 3 biotypes of the b. cereus group. each culture was tested for motility, hemolytic activity on trypticase-soy-sheep blood agar, and rhizoid growth on nutrient agar; carbol-fuchsin stain was used to determine the presence of protein toxin crystals. cultures were identified as b. cereus (biotyp ... | 1982 | 6813307 |
| [cytochemical changes in the peripheral blood leukocytes of guinea pigs inoculated against plague, tularemia and anthrax]. | the immunization of guinea pigs with trivaccine and monovaccines against plaque, tularemia and anthrax induces a decrease in the activity of acidic phosphatase in lymphocytes, as well as a decrease in the number of lymphocytes containing this enzyme. a decrease in the activity of alkaline phosphatase and peroxidase had been found to occur in neutrophil leukocytes. besides, neutrophil leukocytes have shown an increase in the activity of acidic phosphatase and nonspecific esterases. the study base ... | 1982 | 6812331 |
| [a simple micromethod for the determination of specific igg content against bacterial somatic antigens in rabbit immune sera by a modified enzyme immunoassay]. | 1982 | 6810590 | |
| [epidemiological situation of human carbuncle in upper volta (author's transl)]. | after the statistical statement concerning human carbuncle in upper volta in 1976, 1977 and 1978, the authors report their clinical and epidemiological ascertainments observed during the opportunity of four surveys. among the cutaneous forms, cephalic localization is the most frequently observed. visceral forms are essentially digestive, sometimes respiratory, never neurological. in its voltaic foci (grounds made of clayey alluvium, regulatory flooded), carbuncle stretches to endemic-sporadic fo ... | 1982 | 6809350 |
| [robert koch, founder of modern microbiology]. | 1982 | 6808776 | |
| [a hundred years ago: robert koch discovers the agent of tuberculosis]. | 1982 | 6808663 | |
| an 1898 report by gamaleya for a lytic agent specific for bacillus anthracis. | 1982 | 6806352 | |
| anthrax island. | 1982 | 6803170 | |
| evaluation of a microfluorometer in immunofluorescence assays of individual spores of bacillus anthracis and bacillus cereus. | a microfluorometer was constructed by modifying a standard fluorescent microscope with a fibre optic eyepiece and a simple photometric system. it was evaluated in direct immunofluorescence assays of bacillus anthracis and bacillus cereus spores immobilised on multispot microscope slides. from measurements of stable fluorescent crystals comparable in size to the spores, it was inferred that the fluorescence intensity of a stained bacterium could be measured with good precision. fluctuation of a e ... | 1982 | 6802901 |
| anthrax meningitis. | 1981 | 6800657 | |
| anthrax island. | 1982 | 6799833 | |
| a new test of differentiation of bacillus cereus and bacillus anthracis based on the existence of spore appendages. | 1981 | 6799753 | |
| anthrax surveillance 1961-80. | 1982 | 6799106 | |
| bacillus anthracis on gruinard island. | 1981 | 6795509 | |
| observations on infections associated with south wales natural waters. | 1981 | 6795173 | |
| [stability of the chief properties of live anthrax vaccine produced in liquid and solid nutrient media]. | 1981 | 6792839 | |
| anthrax. | 1981 | 6792089 | |
| [immunogenic effect of anthrax protective antigen]. | in experimental immunization of sheep and goats against anthrax the vaccine containing our own protective antigen (pa) whose serological activity was evaluated by the titre 1:16 was used. pa was adsorbed on aluminium hydroxide gel at the ratio 30 parts of gel and 100 parts of antigen. in the control experiment the doses of the virulent anthrax strain were as follows: 10(6) (sheep) and 5.10(6) (goats). the single vaccination provided only 60% protection, the repeated 100% protection. by the titra ... | 1981 | 6791360 |
| anthrax meningitis, a rare clinical entity. | 1981 | 6790511 | |
| [human carbuncle (anthrax) presentation of a case]. | a case of human anthrax in a 12-month-old child is presented. most recent literature and pathophysiology of this disease was reviewed. our attention was called upon patient's age, rarity of this disease in our country and mainly, the form of presentation which difficulted the clinical and laboratory diagnosis. it was characterized by the presence of pustules over the entire surface of the body, with respiratory and neurological manifestations. diagnosis was made on the basis of cultures of skin ... | 1981 | 6789847 |
| [anthrax]. | 1981 | 6789028 | |
| comparison of growth and toxin production in two vaccine strains of bacillus anthracis. | two vaccine strains of bacillus anthracis were monitored in a 10-liter fermentor to compare growth patterns and toxin production. under identical conditions, the sterne strain produced all three components of anthrax toxin, whereas strain v770 produced only the protective antigen. | 1981 | 6787986 |
| determination of the physicochemical and microbiological quality of carcass, bone and blood meal. | the ph value and the moisture, fat and protein content of abattoir by-products which are commercially available in the republic of south africa were examined, and the total bacterial count and the extent of salmonella, escherichia coli, bacillus, yeast and fungus contamination were determined. the extremes and reasonably attainable quality standards were deduced from the highest frequency and mean values of these figures. the total bacterial count was not statistically predictable from variables ... | 1980 | 6785682 |
| the occurrence and significance to animal health of leptospira, mycobacterium, escherichia coli, brucella abortus and bacillus anthracis in sewage and sewage sludges. | samples of sewage, sewage sludge and sewage effluent from one or more of four sewage treatment plants were examined for the presence of leptospira, mycobacterium, escherichia coli, brucella abortus and bacillus anthracis. brucella abortus and bacillus anthracis were not isolated. eleven strains of e. coli potentially enteropathogenic for calves or piglets, eight pathogenic strains of mycobacterium and one patho;genic leptospira strain were isolated from 101, 189 and 189 samples respectively. sew ... | 1981 | 6780619 |
| [survival of anthrax spores on surfaces (author's transl)]. | the survival of spores of bac. anthracis on the surfaces of wood, resopal, aluminum, teflon, pvc, lacquered sheet metal and ceramics was investigated during a period of 987 days. two figures are showing the logarithmical reduction rates of germ counts on these materials. the lowest reduction rates were found on wood, the highest on ceramics. on dark surfaces the reduction rate was not as high as on light ones. the increase of relative humidity from 35% to 45% seems to enforce th inactivation of ... | 1980 | 6779445 |