Publications

TitleAbstractYear
Filter
PMID(sorted descending)
Filter
between-year variation and spatial dynamics of cryptosporidium spp. and giardia spp. infections in naturally infected rodent populations.prevalence and abundance of cryptosporidium spp. and giardia spp. infections were studied over the 8-year period in 3 species of rodents in n.e. poland (bank vole myodes glareolus-1523; yellow-necked mouse apodemus flavicollis- 638; common vole microtus arvalis- 419). prevalence was 53.8, 28.1 and 62.3% respectively for cryptosporidium spp. and 58.3, 24.4 and 74.2% respectively for giardia spp. prevalence and abundance of infection varied markedly across 8 years of the study with 1998 and 2002 b ...200818992178
island selection on mammalian life-histories: genetic differentiation in offspring size.since darwin's pioneering work, evolutionary changes in isolated island populations of vertebrates have continued to provide the strongest evidence for the theory of natural selection. besides macro-evolutionary changes, micro-evolutionary changes and the relative importance of natural selection vs. genetic drift are under intense investigation. our study focuses on the genetic differentiation in morphological and life-history traits in insular populations of a small mammal the bank vole myodes ...200818954431
laboratory model of adaptive radiation: a selection experiment in the bank vole.in a laboratory colony of a wild rodent, the bank vole myodes (=clethrionomys) glareolus, a multiway artificial selection experiment was applied to mimic evolution toward high aerobic metabolism achieved during locomotor activity, predatory behavior, and ability to cope with herbivorous diet. four lines for each of the selection directions and four unselected control lines have been maintained. after three generations of within-family selection, the maximum rate of oxygen consumption achieved du ...201018781839
nmr structure of the bank vole prion protein at 20 degrees c contains a structured loop of residues 165-171.the recent introduction of bank vole (clethrionomys glareolus) as an additional laboratory animal for research on prion diseases revealed an important difference when compared to the mouse and the syrian hamster, since bank voles show a high susceptibility to infection by brain homogenates from a wide range of diseased species such as sheep, goats, and humans. in this context, we determined the nmr structure of the c-terminal globular domain of the recombinant bank vole prion protein (bvprp) [bv ...200818773909
time series analysis performed on nephropathia epidemica in humans of northern sweden in relation to bank vole population dynamic and the nao index.time series analysis was performed on two data series of human nephropathia epidemica (ne) infections in northern sweden between the years 1959-1975 and 1985-2006. the analysis confirms that the bank vole (myodes glareolus), the main reservoir species, shows regular peaks in population density approximately every fourth year. the periodicity in ne cases of the more recent time period (1985-2006) is 2.8-3.3 years and the older period shows a periodicity ranging 3.4-4.2 years, but this is not sign ...200918771520
puumala hantavirus excretion kinetics in bank voles (myodes glareolus).puumala hantavirus is present in bank voles (myodes glareolus) and is believed to be spread mainly by contaminated excretions. in this study, we subcutaneously inoculated 10 bank voles with puumala virus and sampled excretions until day 133 postinfection. levels of shed viral rna peaked within 11-28, 14-21, and 11-28 days postinfection for saliva, urine, and feces, respectively. the latest detection of viral rna was 84, 44, and 44 days postinfection in saliva, urine, and feces, respectively. in ...200818680643
prion protein amino acid determinants of differential susceptibility and molecular feature of prion strains in mice and voles.the bank vole is a rodent susceptible to different prion strains from humans and various animal species. we analyzed the transmission features of different prions in a panel of seven rodent species which showed various degrees of phylogenetic affinity and specific prion protein (prp) sequence divergences in order to investigate the basis of vole susceptibility in comparison to other rodent models. at first, we found a differential susceptibility of bank and field voles compared to c57bl/6 and wo ...200818654630
behaviour and resource use of two competing vole species under shared predation risk.indirect interaction between two competing species via a shared predator may be an important determinant of population and community dynamics. we studied the effect of predation risk imposed by the least weasel mustela nivalis nivalis on space use, foraging and activity of two competing vole species, the grey-sided vole myodes rufocanus, and the bank vole myodes glareolus. the experiment was conducted in a large indoor arena, consisting of microhabitat structures providing food, shelter, trees f ...200818612651
hantavirus disease (nephropathia epidemica) in belgium: effects of tree seed production and climate.recently, human cases of nephropathia epidemica (ne) due to puumala virus infection in europe have increased. following the hypothesis that high reservoir host abundance induces higher transmission rates to humans, explanations for this altered epidemiology must be sought in factors that cause bank vole (myodes glareolus) abundance peaks. in western europe, these abundance peaks are often related to high tree seed production, which is supposedly triggered by specific weather conditions. we evalu ...200918606026
temporal and between-site variation in helminth communities of bank voles ( myodes glareolus) from n.e. poland. 1. regional fauna and component community levels.helminth infections were studied in bank voles (myodes glareolus) from 3 woodland sites in n.e. poland in the late summers of 1999 and 2002, to assess the temporal stability of derived statistics describing the regional helminth fauna and component community structure, and spatial influence on the latter. regional helminth fauna changed dramatically between the two years, primarily due to a fall in the abundance of syphacia petrusewiczi but was partially compensated for by an increase in mesoces ...200818598578
[the role of natural environment in spreading of hantavirus--model of the correlation between host, pathogen and human infections].the environmental changes caused by humans influence ecosystem and thus have significant impact on occurrence of emerging and re-emerging diseases. the hantavirus infection belong to the one of them. the aim of this paper was to present current knowledge about relationship between hantavirus, their natural host and the spread of the infection to people. rodents constitute both the natural host of the hantaviruses and the reservoir of hantavirus for environment. circulation of the virus in the ro ...200718572496
accumulation of point mutations and reassortment of genomic rna segments are involved in the microevolution of puumala hantavirus in a bank vole (myodes glareolus) population.the genetic diversity of puumala hantavirus (puuv) was studied in a local population of its natural host, the bank vole (myodes glareolus). the trapping area (2.5 x 2.5 km) at konnevesi, central finland, included 14 trapping sites, at least 500 m apart; altogether, 147 voles were captured during may and october 2005. partial sequences of the s, m and l viral genome segments were recovered from 40 animals. seven, 12 and 17 variants were detected for the s, m and l sequences, respectively; these r ...200818559935
detection of all known parechoviruses by real-time pcr.the parechovirus genus of the picornaviridae family contains two species, human parechovirus (hpev) and ljungan virus (lv). the hpevs (including the former echoviruses 22 and 23, now hpev type 1 (hpev1) and hpev2, respectively) cause a wide spectrum of disease, including aseptic meningitis, gastroenteritis, encephalitis, acute respiratory illness, and neonatal sepsis-like disease. the lvs were isolated from bank voles in sweden during a search for an infectious agent linked to fatal myocarditis ...200818524969
temporal and between-site variation in helminth communities of bank voles ( myodes glareolus) from n.e. poland. 2. the infracommunity level.the relative importance of temporal and spatial effects was assessed in helminth communities of bank voles (myodes glareolus) in 3 woodland sites in n.e. poland in the late summers of 1999 and 2002. among common species the rank order of sites in relation to prevalence and abundance of infection was maintained between surveys. site effects accounted for most of the deviance (in statistical models), and time was less important, so the exact location from which voles were sampled was of critical i ...200818513460
[hantavirus infections].hantaviruses are enveloped single-stranded ribonucleic acid (rna) viruses that belong to the family bunyaviridae. they are widely distributed and maintained in populations of specific insectivores or rodent host species (mice or rats). in their natural host, hantaviruses develop persistent and asymptomatic infections with lifelong virus shedding in excreta. transmission to humans occurs via direct contact with faeces, urine and saliva of infected rodents, in particular by inhaling virus contamin ...200818497244
male rank affects reproductive success and offspring performance in bank voles.laboratory studies reveal that in several rodent species the females prefer dominant males as mating partners. here we investigate the correlation between males' social rank and their reproductive success. similar numbers of females mating with relatively more dominant or relatively more subordinate males produced a litter, and parturition took place 19-21 days after mating. relatively more dominant males tended to sire more pups than did relatively more subordinates, but the mean number of offs ...200818495182
molecular and serological evidence of borrelia burgdorferi sensu lato in wild rodents in the czech republic.the aim of the present study was to determine the frequency and spatial distribution of the borrelia species in wild rodents in the czech republic. in total, 293 muscle tissue samples and 106 sera from 293 wild rodents captured in north bohemia and north-east and south moravia were examined for the presence of borrelia spp. and antibodies. muscle samples were investigated with real-time polymerase chain reaction (pcr) with a reca primer set, with dna quantification and melting curve analysis, an ...200818454596
estimating the exposure of small mammals at three sites within the chernobyl exclusion zone--a test application of the erica tool.an essential step in the development of any modelling tool is the validation of its predictions. this paper describes a study conducted within the chernobyl exclusion zone to acquire data to conduct an independent test of the predictions of the erica tool which is designed for use in assessments of radiological risk to the environment. small mammals were repeatedly trapped at three woodland sites between early july and mid-august 2005. thermoluminescent dosimeters mounted on collars were fitted ...200818450342
[fleas community in introduced siberian chipmunks (tamias sibiricus laxmann) in forest of sénart, france].we examined the fleas community in an introduced population of siberian chipmunks, tamias sibiricus, between 2005 and 2007, in the forest of sénart (essonne, france). we collected and identified 383 fleas on 463 chipmunks (total: 1,891 captures on 471 chipmunks). in 2005, 120 fleas were also collected on 65 bank voles, clethrionomys glareolus, and on 25 wood mice, apodemus sylvaticus, trapped within the same area. ceratophyllus sciurorum sciurorum formed 73.6% of the chipmunks' flea community, w ...200818416245
bartonella spp. infection in rodents from different habitats in the mazury lake district, northeast poland.four rodent species (clethrionomys glareolus, apodemus flavicollis, microtus arvalis, m. oeconomus) were captured in the period 2004-2006 in the mazury lake district, northeast poland, to determine the prevalence and genetic diversity of bartonella species. the presence of bartonellae was assessed using polymerase chain reaction (pcr) with primers cs140f and bhcs1137n, amplifying a fragment of the glta gene. bartonella dna was detected in 313 (30.6%) of 1024 rodents sampled: in 181 c. glareolus, ...200818399782
ecological and biological factors involved in the transmission of echinococcus multilocularis in the french ardennes.in order to identify the respective importance of the ecological and biological factors involved in the transmission of echinococcus multilocularis, we estimated grassland vole intermediate host (microtus sp. and arvicola terrestris) population densities, in relation to the diet of the definitive host (red fox, vulpes vulpes) and with the prevalence of e. multilocularis in the fox population. the study was conducted in the ardennes, north-eastern france, which is an area with a high incidence of ...200818394209
population, environmental, and community effects on local bank vole (myodes glareolus) puumala virus infection in an area with low human incidence.in this study, the distribution of puumala hantavirus (puuv) infection in local bank vole myodes glareolus populations in an area with low human puuv infection (nephropathia epidemica [ne]) incidence in northern belgium was monitored for 2 consecutive years. bank voles were trapped in preferred habitat and tested for anti-puuv igg. infection data were related to individual bank vole features, population demography, and environmental variables. rare occurrence of puuv infection was found and puuv ...200818370592
spatial and temporal patterning of bank vole demography and the epidemiology of the puumala hantavirus in northeastern france.epidemiological data from bank voles, myodes glareolus, naturally infected by the hantavirus puumala (puuv) were collected by a capture-mark-recapture protocol from 2000 to 2002 in the french department of ardennes. four monitored trapping sites were established in two forests located in two cantons (flize and monthermé). we captured 912 bank voles corresponding to 557 different individuals during 8820 trapping nights for an overall trapping success of 10.34%. the average puuv seroprevalence was ...200818325126
prevalence of toxoplasma gondii in small mammals from the ardennes region, france.serum samples from 218 small mammals trapped in forest and grassland in the ardennes region (north-eastern france) were tested for antibodies to toxoplasma gondii. using the modified agglutination test, positive results were found in 4/92 apodemus sp., 3/64 clethrionomys glareolus, 0/26 microtus agrestis, 0/4 micromys minutus, 3/5 sorex sp., 2/9 arvicola terrestris, and 7/18 talpa europaea. toxoplasma gondii was not isolated from the heart of seropositive individuals after bioassay in mice. sero ...200718303774
frequency and density-dependent selection on life-history strategies--a field experiment.negative frequency-dependence, which favors rare genotypes, promotes the maintenance of genetic variability and is of interest as a potential explanation for genetic differentiation. density-dependent selection may also promote cyclic changes in frequencies of genotypes. here we show evidence for both density-dependent and negative frequency-dependent selection on opposite life-history tactics (low or high reproductive effort, re) in the bank vole (myodes glareolus). density-dependent selection ...200818301764
puumala hantavirus genetic variability in an endemic region (northern sweden).puumala hantavirus (puuv), naturally harboured and shed by bank voles (myodes [clethrionomys] glareolus), is the etiological agent to nephropathia epidemica (ne), a mild haemorrhagic fever with renal syndrome. both host and virus are found throughout much of the european continent and in northern sweden ne is the second most prevalent serious febrile viral infection after influenza. the reliability of diagnostics by pcr depends on genetic variability for the detection of viral nucleic acids in u ...200818296126
estrogens: a new player in spermatogenesis.the mammalian testis serves two main functions: production of spermatozoa and synthesis of steroids; among them, estrogens are the end products obtained from the irreversible transformation of androgens by aromatase. the aromatase is encoded by a single gene (cyp19) in humans which contains 18 exons, 9 of them being translated. in rat the aromatase activity is mainly located in sertoli cells of immature animals and then in leydig cells of adults. moreover rat germ cells represent an additional s ...200718292817
transfer of mitochondrial genome of the northern redbacked vole (clethrionomys rutilus) to the bank vole (c. glareolus) in northwestern europe. 201718274484
long-term fitness benefits of polyandry in a small mammal, the bank vole clethrionomys glareolus.polyandry, i.e. mating with multiple males within one reproductive event, is a common female mating strategy but its adaptive function is often unclear. we tested whether polyandrous females gain genetic benefits by comparing fitness traits of monandrous (mated twice with a single male) and polyandrous (mated twice with two different males) female bank voles clethrionomys glareolus. we raised the offspring in the laboratory until adulthood and measured their body size, before releasing them to o ...200818270151
eye morphology in some wild rodents.the eye anatomy of six rodent species (murinae: apodemus sylvaticus, mus domesticus, and mus spretus; arvicolinae: clethrionomys glareolus, arvicola terrestris and microtus arvalis) was compared by means of light or electron microscopy to determine adaptive, and evolutive signals. our observations revealed inter-specific morphological differences, which were moderate among representatives of the same subfamily. specifically, traits that distinguished murines from arvicolines were the globe's rel ...200818197899
echinococcus multilocularis in belgium: prevalence in red foxes (vulpes vulpes) and in different species of potential intermediate hosts.echinococcus multilocularis causes a rare but potentially lethal zoonotic infection in humans. this tapeworm is known to be endemic in foxes in several countries of western and central europe. in western europe, the common vole (microtus arvalis) and the water vole (arvicola terrestris) are considered to be the most important intermediate host species of this cestode whereas the red fox is by far the most important final host. the purpose of this study was to provide data on the prevalences in w ...200818164551
a cell line infectible by prion strains from different species.it has been shown previously that ovine prion protein (prp(c)) renders rabbit epithelial rk13 cells permissive to the multiplication of ovine prions, thus providing evidence that species barriers can be crossed in cultured cells through the expression of a relevant prp(c). the present study significantly extended this observation by showing that mouse and bank vole prions can be propagated in rk13 cells that express the corresponding prp(c). importantly, the respective molecular patterns of abno ...200818089759
survival of male tengmalm's owls increases with cover of old forest in their territory.the loss and fragmentation of forest habitats have been considered to pose a worldwide threat to the viability of forest-dwelling animals, especially to species that occupy old forests. we investigated whether the annual survival of sedentary male tengmalm's owls aegolius funereus was associated with the cover of old coniferous forests in finland. survival and recapture probabilities varied annually with density changes in populations of the main prey (microtus voles). when this variation was co ...200818080142
environmental conditions and puumala virus transmission in belgium.non-vector-borne zoonoses such as puumala hantavirus (puuv) can be transmitted directly, by physical contact between infected and susceptible hosts, or indirectly, with the environment as an intermediate. the objective of this study is to better understand the causal link between environmental features and puuv prevalence in bank vole population in belgium, and hence with transmission risk to humans. our hypothesis was that environmental conditions controlling the direct and indirect transmissio ...200718078526
[the impact of nematode invasions on the pattern of cryptosporidium parvum infection in wild rodents].fragmentation of the environment by natural barriers (lakes, mountain ranges) and human activities (towns, major roads, agriculture) can lead to isolated subpopulations of hosts. the study was carried out in mazury lake district in north-east of poland, the region rich in forests, lakes, rivers and canals, which are able to create passable such barriers. population of bank voles (myodes glareolus) and yellow-necked mice (apodemus flavicollis)--dominant woodland rodents--showed local differences ...200718075159
kinship, dispersal and hantavirus transmission in bank and common voles.hantaviruses are among the main emerging infectious agents in europe. their mode of transmission in natura is still not well known. in particular, social features and behaviours could be crucial for understanding the persistence and the spread of hantaviruses in rodent populations. here, we investigated the importance of kinclustering and dispersal in hantavirus transmission by combining a fine-scale spatiotemporal survey (4 km2) and a population genetics approach. two specific host-hantavirus s ...200818071626
[structure of populations and ecological nishes of ectoparasites in the parasite communities of small forest mammals].the paper reports the results of eight-year investigations on the ectoparasites of rodents and insectivores carried out in southern taiga of the ilmen-volkhov lowland (novgorod region) and kurgolovsky reserve (leningrad region). twelve species of small mammals were captured including three dominate species--bank vole clethrionomys glareolus (2722 specimens), common shrew sorex araneus (1658 specimens), and wood mouse apodemus uralensis (367 specimens). parasite community of the bank vole compris ...200718052001
[the estimation of 90sr and 137cs excretion parameters from the organism of wild and laboratory small mammals in vivo, after natural contamination of them in the chernobyl zone].in the course of laboratory experiment, parameters of 90sr and 137cs excretion were estimated in individuals of bank vole clethrionomys glareolus, captured at one of the most contaminated sites of the chernobyl zone. the animals were kept under laboratory conditions using "clean" feed during 50 days. the similar investigation was carried out with laboratory mice mus musculus (big blue line) during a longer period (184 days). the measurements of 90sr content in the animals' body were in vivo carr ...200718051678
borrelia burgdorferi sensu lato in siberian chipmunks (tamias sibiricus) introduced in suburban forests in france.numerous vertebrate reservoirs have been described for borrelia burgdorferi sensu lato (sl), which includes the etiological agents of lyme borreliosis (lb). the siberian chipmunk (tamias sibiricus) is a rodent originating from asia, where it is suspected to be a b. burgdorferi reservoir. it has been intentionally released into the wild in europe since the 1970s, but has not yet been subject to any study regarding its association with the lb agent. in this paper we studied siberian chipmunk infes ...200718021026
infanticide in the evolution of reproductive synchrony: effects on reproductive success.synchronous breeding in animals and plants has stimulated both a theoretical and empirical examination of the possible benefits of active synchronization. the selective pressures of predation and infanticide are the strongest candidates proposed to explain the evolution of reproductive synchrony. alternatively, breeding asynchronously with conspecifics may ensure a greater availability of resources per breeder. however, the possible fitness benefits resulting from active asynchronization have no ...200817983462
ultrasonic calls of bank vole pups isolated and exposed to cold or to nest odor.bank vole pups produce ultrasounds when isolated from the nest, as other rodents do. the present study was intended to elucidate the possible interaction between the social stress of isolation from the mother and the physical stress of low ambient temperature during the nesting period. although bank vole pups removed from nests and monitored at nest temperature vocalized at high frequency, the number and duration of signals increased at lower ambient temperature. in the tested voles it appears t ...200817961612
field survey of rodents for hepatozoon infections in an endemic focus of american canine hepatozoonosis.eighteen of 31 (58%) cotton rats (sigmodon hispidus) and 8 of 24 (33.3%) white-footed mice (peromyscus leucopus) that were wild-trapped from 4 american canine hepatozoonosis endemic sites in oklahoma were infected with hepatozoon species. the predilection organ for merogony of the hepatozoon species in cotton rats was the liver. meronts were not detected in any of the white-footed mice. a 488 bp dna fragment that includes a variable region of the 18s rrna hepatozoon gene amplified from blood or ...200717942230
the cost of reproduction induced by body size at birth and breeding density.body size at birth has implications for the quality of individuals throughout their life. although large body size is generally considered an advantage, the relationship between body size at birth and long-term fitness is often complicated. under spatial or temporal variation in environmental conditions, such as the seasonally changing densities of fennoscandian vole populations, selection should favor variation in offspring phenotypes, as different qualities may be beneficial in different condi ...200717924957
[identification of a new puumala hantavirus subtype in rodents from china].in order to detect the nucleic acid of puumala hantavirus, rna was extracted from lungs of bank voles captured in northeast china, and partial s and m genome segments of puumala virus were amplified by rt-pcr and sequenced. phylogenetic analysis suggested that chinese puumala virus had diverged from the common node of puuv, with accumulating nucleotide substitutions and formed a distinct lineage from other puumala viruses. newly found puumala virus was most closely related to the kamiiso-8cr-95 ...200717894236
parasite fauna of the bank vole (clethrionomys glareolus) in an urban region of germany: reservoir host of zoonotic metazoan parasites?in the present study, 29 bank voles (clethrionomys glareolus) were studied for their endo- and ectoparasite fauna. the rodents were trapped in dormagen, a city in north rhine-westphalia, germany. a total of ten different parasite species were identified: four endoparasite (four nematoda) and six ectoparasite (three insecta, three arachnida) species. the predominant endoparasite was the nematode aonchotheca murissylvatici, followed by the nematode heligmosomum costellatum, while the flea ctenopht ...200717849150
endemic hantavirus infection impairs the winter survival of its rodent host.the influence of pathogens on host fitness is one of the key questions in infection ecology. hantaviruses have coevolved with their hosts and are generally thought to have little or no effect on host survival or reproduction. we examined the effect of puumala virus (puuv) infection on the winter survival of bank voles (myodes glareolus), the host of this virus. the data were collected by monitoring 22 islands over three consecutive winters (a total of 55 island populations) in an endemic area of ...200717824420
sex- and concentration-dependent effects of predator feces on seasonal regulation of body mass in the bank vole clethrionomys glareolus.increased perception of predation risk can cause changes in activity, feeding and reproductive behavior in a wide range of taxa. many small mammals in the temperate zone exhibit fluctuations in body mass in response to changing photoperiod. bank voles lose body mass in winter which they regain when photoperiod increases in the spring. to determine if predation risk affects seasonal changes in body mass (bm), bank voles were exposed to two concentrations (low: lc and high: hc) of weasel feces. fo ...200717822704
[skin lesions in small mammals parasitized by psorergates apodemi and p. dissimilis (gheyletoidea: psorergatidae)].histopathology in the sites of localization and parasiting of the mites psorergates apodemi fain et al., 1966 and p. dissimilis fain et al., 1966 on the ural field mouse apodemus uralensis (pallas) and the bank vole clethrionomys glareolus (schreber) is described. the mites affected all epidermis cell layers down to the cambium layer and caused hyperkeratosis.200717722644
mitochondrial control region variation in bank voles (clethrionomys glareolus) is not related to chernobyl radiation exposure.three previous studies at chernobyl, ukraine, documented elevated mitochondrial dna diversity in bank voles (clethrionomys glareolus) from radioactively contaminated sites. little evidence was found to link patterns of diversity in contaminated areas to radiation exposure, but the experimental design precluded discriminating among alternative explanations for elevated diversity in exposed groups. reference sites selected for the studies were relatively distant from contaminated sites and, additi ...200717713225
distribution of androgen receptor and steroid hormone concentrations in ovaries of immature bank voles: effect of photoperiod.immunolocalisation of androgen receptor (ar) and steroid contents were analyzed in the ovaries of 7- and 14-day-old bank voles, reared in a long (ld) and short (sd) photoperiod. the strongest ar immunoreaction was found in the stromal cells, especially in the ovaries of 7-day-old animals, and in the granulosa cells of all types of ovarian follicles. oocytes and the cells of surface epithelium were ar positive. the amount of ovarian androgens was relatively high, whereas the level of estradiol wa ...200717707468
tick-borne zoonotic bacteria in wild and domestic small mammals in northern spain.the prevalence and diversity of tick-borne zoonotic bacteria (borrelia spp., anaplasma phagocytophilum, coxiella burnetii, and spotted fever group rickettsiae) infecting 253 small mammals captured in the basque country (spain) were assessed using pcr and reverse line blot hybridization. trapping sites were selected around sheep farms (study 1, 2000 to 2002) and recreational parks (study 2, 2003 to 2005). the majority of the studied mammals (162) were wood mice (apodemus sylvaticus), but six othe ...200717693556
association between the dqa mhc class ii gene and puumala virus infection in myodes glareolus, the bank vole.puumala virus (puuv) is a hantavirus specifically harboured by the bank vole, myodes (earlier clethrionomys) glareolus. it causes a mild form of hemorrhagic fever with renal syndrome (hfrs) in humans, called nephropathia epidemica (ne). the clinical severity of ne is variable among patients and depends on their major histocompatibility complex (mhc) genetic background. in this study we investigated the potential role of class ii mhc gene polymorphism in the susceptibility/resistance to puuv in t ...200817693139
characterization of beta-cell function of pancreatic islets isolated from bank voles developing glucose intolerance/diabetes: an animal model showing features of both type 1 and type 2 diabetes mellitus, and a possible role of the ljungan virus.bank voles (clethrionomys glareolus) kept in captivity develop diabetes mellitus to a significant extent. also in wild bank voles, elevated blood glucose has been observed. a newly isolated picornavirus named ljungan virus (lv) has been found in the pancreas of these bank voles. moreover, lv infection in combination with environmental factors may cause glucose intolerance/diabetes (gint/d) in normal mice. the aim of the present study was to investigate the functional characteristics of pancreati ...200717686482
an attempt to control a natural focus of leptospirosis grippotyphosa by rodenticide--a long-term study (1977-2004).the purpose of the study was to suppress a known natural focus of field fever exerting an influence on animal hosts of leptospires--small terrestrial mammals (s.t.m.) by rodenticide. after repeated application of the zinc phosphide rodenticide, the s.t.m. were regularly live-trapped and checked for leptospirosis by dark-field microscopy and culture of their renal tissue and serological examination. isolated leptospira strains were typed by help of rabbit factor sera. the deratization influenced ...200717655177
replication of ljungan virus in cell culture: the genomic 5'-end, infectious cdna clones and host cell response to viral infections.ljungan virus (lv) is a picornavirus recently isolated from bank voles (clethrionomys glareolus). the previously uncharacterised 5'-end sequence of the lv genome was determined. infectious cdna clones were constructed of the wild type lv prototype strain 87-012 and of the cytolytically replicating cell culture adapted variant 87-012g. virus generated from cdna clones showed identical growth characteristics as uncloned virus stocks. cell culture adapted lv, 87-012g, showed a clear cytopathic effe ...200717645978
ecological differences and coexistence in a guild of microparasites: bartonella in wild rodents.the study of ecological differences among coexisting microparasites has been largely neglected, but it addresses important and unusual issues because there is no clear distinction in such cases between conventional (resource) and apparent competition. here patterns in the population dynamics are examined for four species of bartonella (bacterial parasites) coexisting in two wild rodent hosts, bank voles (clethrionomys glareolus) and wood mice (apodemus sylvaticus). using generalized linear model ...200717645030
hantavirus disease outbreak in germany: limitations of routine serological diagnostics and clustering of virus sequences of human and rodent origin.in europe, hemorrhagic fever with renal syndrome results mainly from infection with puumala virus (puuv) or dobrava virus. for 31 patients from a hantavirus disease outbreak in lower bavaria, a district in southeast germany, serodiagnosis was undertaken by enzyme-linked immunosorbent assay, immunofluorescence assay, and immunoblot analysis. in a few of these cases, however, puuv-specific typing of antibodies by these standard assays failed and a virus neutralization assay under biosafety level 3 ...200717626170
signal reliability compromised by genotype-by-environment interaction and potential mechanisms for its preservation.sexual selection based on signaling requires that signals used by females in mate choice are reliable indicators of a male's heritable total fitness. a signal and the preference for it are expected to be heritable, resulting in the maintenance of genetic covariance between these two traits. however, a recent article has proposed that signals may quickly become unreliable in the presence of both environmental variation and genotype-by-environment interaction (g x e) with crossing reaction norms, ...200717598753
estrogens and male reproduction: a new concept.the mammalian testis serves two main functions: production of spermatozoa and synthesis of steroids; among them estrogens are the end products obtained from the irreversible transformation of androgens by a microsomal enzymatic complex named aromatase. the aromatase is encoded by a single gene (cyp19) in humans which contains 18 exons, 9 of them being translated. in rats, the aromatase activity is mainly located in sertoli cells of immature rats and then in leydig cells of adult rats. we have de ...200717581673
joint effects of dietary cadmium and polychlorinated biphenyls on metallothionein induction, lipid peroxidation and histopathology in the kidneys and liver of bank voles.free-living bank voles have been shown to be more sensitive to cadmium (cd) toxicity than the rodents exposed to cd under laboratory conditions. the present study was designed to find out whether polychlorinated biphenyls (pcbs), common environmental co-contaminants, increase susceptibility to cd toxicity through inhibition of metallothionein (mt) synthesis-a low molecular weight protein that is considered to be a primary intracellular component of the protective mechanism. for 12 weeks, the mal ...200817560650
puumala hantavirus viremia diagnosed by real-time reverse transcriptase pcr using samples from patients with hemorrhagic fever and renal syndrome.puumala virus (puuv) is the endemic hantavirus in northern sweden and causes nephropathia epidemica (ne), a milder form of hemorrhagic fever with renal syndrome. there is a need for fast and reliable diagnostics to differentiate the disease from other infections. by aligning virus rna sequences isolated from 11 different bank voles and one human patient, we designed a real-time reverse transcriptase (rt) pcr method for detection of puuv rna. the real-time rt-pcr assay showed linearity from 20 to ...200717537944
the nerve cells of the neostriatum in the common shrew (sorex araneus) and bank vole (clethrionomys glareolus): a golgi comparative study.the studies were carried out on 12 brains derived from adult representatives of two mammalian orders, insectivora and rodentia. the neostriatum was compared in the common shrew (sorex araneus) and bank vole (clethrionomys glareolus). three main types of striatal neuron were distinguished in the common shrew and five types of neurons in the bank vole. the fifth type of bank vole neurons was additionally divided into two subtypes with respect to dendritic pattern.200717533595
puumala and tula hantaviruses in france.the first genome sequences of tula (tulv) and puumala (puuv) hantaviruses undoubtedly originated from france were recovered from tissue samples of european common voles and bank voles captured in jura region. genetic analysis of s and m segments of french puuv strain revealed its highest similarity to strains from neighboring belgium and germany and also from slovakia. on phylogenetic trees, french puuv strain was placed within the central european lineage formed by strains from these three coun ...200717532080
a new dicrocoeliid from the bank vole clethrionomys glareolus (rodentia: microtidae) from poland.a new dicrocoeliid trematode, brachylecithum glareoli n. sp., is described from the biliary ducts of the bank vole, clethrionomys glareolus, in southwest poland. this is the first dicrocoeliid species described in rodents from poland. it is characterized mainly by the maximum body width at the level of the vitellaria; large, longitudinally oval testes; round, or transversely oval, ovary that is smaller than the testes; vitellaria located in the midbody; cirrus sac dorsally overlapping ventral su ...200717436955
novel prion protein conformation and glycotype in creutzfeldt-jakob disease.to describe a novel molecular and pathological phenotype of creutzfeldt-jakob disease. patient a 69-year-old woman with behavioral and personality changes followed by rapidly evolving dementia.200717420324
heavy-metal concentrations in small mammals from a diffusely polluted floodplain: importance of species- and location-specific characteristics.the soil of several floodplain areas along large european rivers shows increased levels of heavy metals as a relict from past sedimentation of contaminants. these levels may pose risks of accumulation in food webs and toxicologic effects on flora and fauna. however, for floodplains, data on heavy-metal concentrations in vertebrates are scarce. moreover, these environments are characterised by periodical flooding cycles influencing ecologic processes and patterns. to investigate whether the sugge ...200717387425
molecular detection of bartonella species infecting rodents in slovenia.rodents, collected in three zoogeographical regions across slovenia, were tested for the presence of bartonellae using direct pcr-based amplification of 16s/23s rrna gene intergenic spacer region (its) fragments from splenic dna extracts. bartonella dna was detected in four species of rodents, apodemus flavicollis, apodemus sylvaticus, apodemus agrarius and clethrionomys glareolus, in all three zoogeographic regions at an overall prevalence of 40.4%. the prevalence of infection varied significan ...200717374132
[seasonal variation in hematological indices in bank vole (clethrionomys glareolus) in different reproductive states].hematological and hematopoietic indices were studied in various seasons in bank vole in different reproductive states. the seasonal variation in the indices demonstrated patterns typical of each state and reflecting the adaptive response to changed habitat conditions.201617352196
gene duplication, allelic diversity, selection processes and adaptive value of mhc class ii drb genes of the bank vole, clethrionomys glareolus.the generation and maintenance of allelic polymorphism in genes of the major histocompatibility complex (mhc) is a central issue in evolutionary genetics. recently, the focus has changed from ex situ to in situ populations to understand the mechanisms that determine adaptive mhc polymorphism under natural selection. birth-and-death evolution and gene conversion events are considered to generate sequence diversity in mhc genes, which subsequently is maintained by balancing selection through paras ...200717351770
murine gammaherpesvirus 68: a model for the study of epstein-barr virus infections and related diseases.epstein-barr virus (ebv) is a ubiquitous human gammaherpesvirus (ghv) that causes acute infection and establishes life-long latency. ebv is associated with the development of b-cell lymphoproliferative disorders, several malignant cancers, the syndrome of infectious mononucleosis, and chronic interstitial lung disease. although the molecular biology of ebv has been characterized extensively, the associated disease conditions and their pathogenesis are difficult to study in human populations beca ...200717348290
the dynamics of murid gammaherpesvirus 4 within wild, sympatric populations of bank voles and wood mice.murid gammaherpesvirus 4 (muhv-4) is widely used as a small animal model for understanding gammaherpesvirus infections in man. however, there have been no epidemiological studies of the virus in wild populations of small mammals. as muhv-4 both infects cells associated with the respiratory and immune systems and attempts to evade immune control via various molecular mechanisms, infection may reduce immunocompetence with potentially serious fitness consequences for individuals. here we report a l ...200717347391
dioxin exposure in contaminated sawmill area: the use of molar teeth and bone of bank vole (clethrionomys glareolus) and field vole (microtus agrestis) as biomarkers.developmental disorders of teeth are among the most sensitive targets of polychlorinated dibenzo-p-dioxin and -furan (pcdd/f) exposure. in rats, 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) reduces dose-dependently the size of molars, most severely the third lower molars. dioxins also have effects on developing bone, including altered bone mineral density as well as reduced bending breaking force and stiffness. the aim of this study was to evaluate the use of the third lower molar and long bones a ...200717335869
expression of metallothionein genes i and ii in bank vole clethrionomys glareolus populations chronically exposed in situ to heavy metals.the expression of two metallothionein genes (mt-i and mt-ii) in the liver, kidney, and gonad of bank voles collected at four metal-contaminated sites (cd, zn, pb, and fe) were measured using the quantitative real-time pcr method (qpcr). relative mt gene expression was calculated by applying a normalization factor (nf) using the expression of two housekeeping genes, ribosomal 18s and beta-actin. relative mt expression in tissues of animals from contaminated sites was up to 54.8-fold higher than t ...200717328220
the effect of seasonal host birth rates on disease persistence.in this paper, we add seasonality to the birth rate of an sir model with density dependence in the death rate. we find that disease persistence can be explained by considering the average value of the seasonal term. if the basic reproductive ratio r(0)>1 with this average value then the disease will persist and if r(0)<1 with this average value then the disease will die out. however, if the underlying non-seasonal model displays oscillations towards the equilibrium then the dynamics of the seaso ...200717316708
biomagnification of pbdes in three small terrestrial food chains.eight polybrominated diphenyl ethers (pbde) congeners (iupac nos. 28, 47, 99, 100, 153, 154, 183, and 209) were measured in passerines (great tits--parus major), wood mice (apodemus sylvaticus), and bank voles (clethrionomys glareolus). these data were combined with previously obtained data on pbdes in common buzzards (buteo buteo), sparrowhawks (accipiter nisus), and red fox (vulpes vulpes). this enabled estimation of the biomagnification potential of pbdes in the following three terrestrial fo ...200717310700
haemoparasites of common shrews (sorex araneus) in northwest england.the presence of haemoparasites belonging to the taxa anaplasma, bartonella and trypanosoma was determined among 76 common shrews (sorex araneus) from northwest england. anaplasma phagocytophilum dna was recovered from the blood of 1 shrew (1.3%), with the amplified 16s rrna sequence identical to one previously reported from a bank vole (clethrionomys glareolus). trypanosoma spp. dna was detected in 9 shrews (11.8%), the amplified 18s rdna fragments being indistinguishable from one another, and d ...200717288633
abundance of wild rodents, ticks and environmental risk of lyme borreliosis: a longitudinal study in an area of mazury lakes district of poland.the results of a longitudinal epidemiological survey in two contrasting habitats in an area of the mazury lakes district of poland indicate that both host and vector (ixodes ricinus) densities, may be the most important risk factors for the tick-transmitted spirochetes of borrelia burgdirferi s.l. however, the results also highlight that even related host species, such as the wild rodents apodemus flavicollis and clethrionomys glareolus that share the same habitat, can show quite different dynam ...200617196004
tick-borne encephalitis virus in clethrionomys glareolus in the czech republic.a total of 474 specimens from 157 rodents caught at the military training area of boletice in the south of the czech republic from may to november 1999 were screened for tbev by nested pcr. tbev-specific rna was amplified from lung, kidney, and spleen derived from one clethrionomys glareolus in the first rt-pcr round. sequence analysis revealed a 100% identity to the tbev strain neudoerfl. tbev presence in the sample was confirmed by mouse brain passage of backup samples and cell culture. the re ...200617187572
seasonal variations in detecting borrelia burgdorferi sensu lato in rodents from north eastern austria.austria is well known as an endemic area of lyme borreliosis. to assess the annual variation of rodent populations that may host agents of lyme borreliosis we collected rodents in northeastern austria. life traps were set out every six weeks during a year consecutively in one each of the three different zones (hohenau, ernstbrunn, vienna woods) that cover the main habitat characteristics of small mammals in northeastern austria. rodents were collected and identified. samples of heart, urine blad ...200617186171
costs of coexistence along a gradient of competitor densities: an experiment with arvicoline rodents.1. costs of coexistence for species with indirect resource competition usually increase monotonically with competitor numbers. very little is known though about the shape of the cost function for species with direct interference competition. 2. here we report the results of an experiment with two vole species in artificial coexistence in large enclosures, where density of the dominant competitor species (microtus agrestis) was manipulated. experimental populations of the subordinate vole species ...200717184354
the neuronal structure of the dorsal nucleus of the lateral geniculate body in the common shrew (sorex araneus) and the bank vole (clethrionomys glareolus): golgi and nissl studies.the topography and neuronal structure of the dorsal nucleus of the lateral geniculate body (gld) of the common shrew and the bank vole are similar. the lateral geniculate body of both the species examined has a homogeneous structure and no observable cytoarchitectonic lamination. on the basis of the shape of the dendritic arbours as well as the pattern of dendritic arborisations the following two types of neurons were distinguished. type i "bushy" neurons that have multipolar or round perikarya ...200617171615
recognition of kin in bank voles (clethrionomys glareolus).the ability of animals to recognise their kin plays an important role in sexual selection. this study addressed the question of whether there is sibling recognition between young and adult bank vole females and males, and if so, how kin are recognised. the behavioural data from these experiments show that bank vole females can recognise their sibling brothers on the basis of their odours. in two-choice preference tests, prepubertal females were more attracted to the scent of socially known sibli ...200717145068
[species composition, host association and niche differentiation in fleas of small mammals in the ilmen-volkhov lowland].species composition, abundance, annual cycles, and host association of fleas parasitizing small mammals were investigated. the problem of niche differentiation in these insects is considered on the base of the comparative analysis of their annual cycles. the annual cycles of the fleas are revealed to be similar in the case of few number of flea species in parasite community. thus, two species parasitizing sorex araneus (doratopsylla dasycnema and palaeopsylla soricis), as well as three species a ...200617144403
variation in transfer factor of radiocaesium in bank voles (clethrionomys glareolus) in clear cut and mature forest sites after the chernobyl accident.bank voles that were collected between 1986 and 2004 at sites in chernobyl fallout areas of northern sweden showed higher (137)cs activity concentrations at the mature forest sites compared to clear cuts. this difference was not attributed to differences in ground deposition between sites but to differences in aggregated transfer rates to voles. differences in transfer between forest types were evident for all years 1986-2004 but the change occurred at different rates in the two habitats. the ap ...200717137685
quantitative measure of sexual selection with respect to the operational sex ratio: a comparison of selection indices.despite numerous indices proposed to predict the evolution of mating systems, a unified measure of sexual selection has remained elusive. three previous studies have compared indices of sexual selection under laboratory conditions. here, we use a genetic study to compare the most widely used measures of sexual selection in natural populations. we explored the mating and reproductive successes of male and female bank voles, clethrionomys glareolus, across manipulated operational sex ratios (osrs) ...200717134998
cadmium, zinc and iron interactions in the tissues of bank vole clethrionomys glareolus after exposure to low and high doses of cadmium chloride.in present study, bank voles clethrionomys glareolus were peritioneally injected with different doses of cadmium, 0, 1.5, 3.0 mg cd/kg body mass. animals were sacrificed on the 21st day after cadmium exposure and the liver and kidney were obtained for cadmium, zinc and iron analysis using atomic absorption spectrometry. results showed that cadmium had accumulated in the tissues according to dosage and sex. cadmium affected the survival and body masses of dosed females. cadmium decreased the iron ...200717120143
[wild small mammals are the reservoir hosts of the bartonella genus bacteria in the south of moscow region].a total of 103 blood samples collected from wild small mammals captured in the prioksko-terrasny reserve on the south of moscow region were studied to determine the bartonellae prevalence. the examined species were the yellow-necked mice apodemus flavicollis (35 samples), the european wood mouse apodemus uralensis (10 samples), the bank vole clethrionomys glareolus (51 samples), the house mouse mus musculus (3 samples), the common vole microtus arvalis (2 samples), and the shrew sorex araneus (2 ...200617094651
simple epidemiological model predicts the relationships between prevalence and abundance in ixodid ticks.we tested whether the prevalence of ticks can be predicted reliably from a simple epidemiological model that takes into account only mean abundance and its variance. we used data on the abundance and distribution of larvae and nymphs of 2 ixodid ticks parasitic on small mammals (apodemus agrarius, apodemus flavicollis, apodemus uralensis, clethrionomys glareolus and microtus arvalis) in central europe. ixodes trianguliceps is active all year round, occurs in the study area in the mountain and su ...200717032480
dynamics of puumala virus infection in bank voles in ardennes department (france).the hantaviruses (genus hantavirus, family bunyaviridae) include human pathogens and occur worldwide. in western and central europe, the predominant serotype is puumala (puu) virus, which causes epidemic nephropathy. voles are considered to be the main reservoir and the vector of puu virus. a total of 719 rodents (mainly clethrionomys glareolus, apodemus sp.) trapped by capture-mark-recapture (cmr) in four sites in ardennes department (france) between april 2004 and october 2005 were tested for ...200617027178
[echinococcus multilocularis in grisons: distribution in foxes and presence of potential intermediate hosts].the southern border of the european endemic area of echinococcus multilocularis runs along the alpine crest. this endemic transition area was analysed in the canton grisons on a small spatial scale. a total of 543 foxes originating from 10 areas north and 4 areas south of the main alpine divide were investigated. parasites were isolated using the sedimentation and counting technique on intestinal contents. the mean prevalence of e. multilocularis was 6.4% with significant differences between dif ...200617024979
maternal antibodies postpone hantavirus infection and enhance individual breeding success.the transfer of maternal antibodies from mother to progeny is a well-known phenomenon in avian and mammalian species. optimally, they protect the newborn against the pathogens in the environment. the effect of maternal antibodies on microparasite transmission dynamics may have important consequences for both the fitness of the host and the epizootic processes of the pathogens. however, there is a scarcity of studies examining these effects in free-living wild species. we studied the influence of ...200617015326
quantitative profiling of the pathological prion protein allotypes in bank voles by liquid chromatography-mass spectrometry.the conversion of the cellular prion protein (prp(c)) into a misfolded isoform (prp(tse)) that accumulates in the brain of affected individuals is the key feature of transmissible spongiform encephalopaties (tses). susceptibility to tses is influenced by polymorphisms of the prion gene suggesting that the presence of certain amino acid residues may facilitate the pathological conversion. in this work, we describe a quantitative, fast and reliable hplc-ms method that allowed to demonstrate that i ...200717008136
a northern glacial refugium for bank voles (clethrionomys glareolus).there is controversy and uncertainty on how far north there were glacial refugia for temperate species during the pleistocene glaciations and in the extent of the contribution of such refugia to present-day populations. we examined these issues using phylogeographic analysis of a european woodland mammal, the bank vole (clethrionomys glareolus). a bayesian coalescence analysis indicates that a bank vole population survived the height of the last glaciation (approximately 25,000-10,000 years b.p. ...200617001012
puumala hantavirus in slovenia: analyses of s and m segment sequences recovered from patients and rodents.in slovenia, the co-existence of dobrava and puumala (puuv) hantaviruses in a single endemic region has been demonstrated. this study presents selected slovenian hfrs cases caused by puuv combined with genetic analysis of viral genome sequences recovered from clinical specimens and tissue samples of clethrionomys glareolus (bank voles). serum samples from nine hfrs patients were included in the study. rodents study sites were selected with regard to the hfrs cases. partial s segment sequences we ...200716997412
eimeria-parasites are associated with a lowered mother's and offspring's body condition in island and mainland populations of the bank vole.this study, based on correlative data, tests the hypothesis that infections with eimeria spp. parasites exert a significant loss of fitness of bank voles (clethrionomys glareolus) reflected in lower reproductive success and survival, declining host population densities and are associated positively with population size. the study was conducted in 20 mainland and 27 island populations in central finland during may-september in 1999. faecal samples showed that 28% of 767 individuals were infected ...200716948876
[occurrence of lice (anoplura) in rodents from lover silesia].the data on the lice of small mammals, which can be the vectors of some human pathogens, are rather scarce in poland.200516913503
hepatozoon species infection in wild red squirrels (sciurus vulgaris) on the isle of wight.postmortem examinations of 49 red squirrels (sciurus vulgaris) found dead on the isle of wight revealed the presence of a hepatozoon species in 18 of them (37 per cent). the prevalence of infection was highest in subadult animals and no juveniles were infected. the prevalence was higher in the squirrels dying from natural causes (nine of 12) than in squirrels killed in road accidents (seven of 27). the weight of infection varied, and there were heavy infections in squirrels dying from toxoplasmo ...200616905733
[ecological aspects of infection of bank vole clethrionomys glareolus (schreber, 1780) with trypanosoma (herpetosoma) evotomys hadwen, 1912].the studies were carried out in kosewo górne in the mazurian district (north-east region of poland), in september 1995, september 1996 and between may 1997 and june 1998 each month. the animals were trapped in live traps, and after study they were marked and released. the infection of trypanosomes was detected using microhaematocrit centrifugation technique and in blood smears. the intensity of infection had the range from 50 to 150 000 individuals in 1 ml of blood. the maximal prevalence of inf ...200116886428
[the ecology of cryptosporidium parvum infection in small rodent populations].the prevalence and abundance of cryptosporidium parvum were studied over a three year period (1997-1999) in three species of rodents sampled from forest and abandoned fields in the mazury lake district, poland. the overall prevalence was consistently higher in voles compared with apodemus flavicollis (70.6% in clethrionomys glareolus, 73.0% in microtus arvalis and 27.8% in a. flavicollis). the prevalence and abundance of infection also varied across the 3 years of the study with 1998 being the y ...200116886421
[co-infection of borrelia garinii and b. afzelii in a population of wild rodents from woodland].the maintenance of borrelia burgdorferi s.l. in the environment is dependent on the zoonotic cycle involving tick vectors and certain reservoir hosts. it is well known, that the same species of wild rodents, as well as the vector ixodes ricinus, are often co-infected with at least two genomospecies of b. burgdorferi s.l.: b. afzelii and b. garinii. the ticks collected from two rodent species: clethrionomys glareolus and apodemus flavicollis were examined for the presence of b. burgdorferi s.l., ...200116886420
Displaying items 701 - 800 of 1419