Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [analysis of dermatophyte flora at a private clinic in sapporo during the period 1992 to 2001]. | statistical analysis was made of a total of 5530 patients (6798 cases) of dermatophytoses presenting at our private clinic during the period 1992 to 2001. the number of patients and cases represents 8.0% and 9.8% of the entire outpatient population during that time, respectively. sex ratio (male/female) was 1.5. among the 6798 dermatophytoses cases, tinea pedis was most frequent (65.8%), followed by tinea unguium (20.7%), tinea cruris (7.2%), tinea corporis (3.9%), tinea manuum (2.4%) and tinea ... | 2003 | 12913811 |
| recombinant expression and antigenic properties of a 31.5-kda keratinolytic subtilisin-like serine protease from microsporum canis. | a secreted 31.5-kda keratinolytic subtilase (sub3; aj431180) is thought to be a microsporum canis virulence factor and represents a candidate for vaccination trials. in this study, the recombinant keratinase (r-sub3) was produced by the pichia pastoris expression system and purified to homogeneity. recombinant sub3 displayed identical biochemical properties with the native protease. experimentally cutaneously infected guinea pigs showed specific lymphoproliferative response towards r-sub3, while ... | 2003 | 12900052 |
| inhibition of dermatophytes by optical brighteners. | the aim of this study was to investigate a possible effect of optical brighteners on the growth of dermatophytes. typical strains of trichophyton rubrum, t. mentagrophytes, microsporum canis and epidermophyton floccosum were grown on agar plates containing two different brighteners of stilbenedisulfonic acid type in concentrations between 5 x 10(-5) and 1 x 10(-2) mol l-1 and their thallus diameters were compared with controls. in addition, hyphae grown with brighteners were compared with contro ... | 2003 | 12870200 |
| onychomycosis in systemic lupus erythematosus: a case control study. | immunosuppressed patients are prone to develop onychomycosis. in systemic lupus erythematosus (sle) there are no previous studies. we aimed to establish the prevalence, clinical characteristics, and organisms causing onychomycosis in sle patients compared with controls. | 2003 | 12858446 |
| antifungal activity of the methanolic extract and alkaloids of glaucium oxylobum. | the methanolic extract and total alkaloids of the aerial parts of glaucium oxylobum exhibited good activity against microsporum gypseum, microsporum canis, trichophyton mentagrophytes and epidermophyton floccosum. four alkaloids, dicentrine, glaucine, protopine, and alpha-allocryptopine, were identified as the compounds responsible for the antifungal activity of this plant. | 2003 | 12837370 |
| [three years incidence of dermatophytes in a hospital in porto (portugal)]. | we evaluated the incidence of dermatophytes isolated at our hospital in the years of 1997 to 2000 and correlated it with anatomical site and age. trichophyton rubrum was the predominant species in all anatomical sites, excluding scalp, followed by microsporum canis, the leading agent of tinea capitis. all dermatophytosis, except tinea capitis by m. canis and trichophyton schoenleinnii appeared mainly in adult patients. our results revealed no substantial differences to other portuguese studies r ... | 2002 | 12825982 |
| [prevalence of zoophilic dermatophytes in the sarajevo region]. | zoophlic dermatophytes are common cause of tinea infections in europe, especially in mediterranean area. the aim of our study was to determine the prevalence of zoophilic dermatophytes in sarajevo area, during a five-year period (1998-2002). samples (skin scrapings or nail fragments) were taken from 2,142 patients who presented with suspected dermatophytoses and cultured on sabouraud agar. after three weeks of incubations 465 (21.7%) dermatophytes were identified based on macroscopic and microsc ... | 2003 | 12822383 |
| dermatophytes isolated from domestic animals in iran. | between 1994 and 1998, a total of 790 feather, hair and skin specimens from a variety of animals with suspected dermatophytoses were studied, of which 248 (31.4%) yielded dermatophytes. the most frequent dermatophytes isolated were microsporum canis (38.3%), trichophyton verrucosum (31.8%), t. mentagrophytes (13.3%) and m. gypseum (7.7%). there was a significantly higher proportion of positive cultures from cats (54.8%) than dogs (8.2%), and m. canis was the most common species isolated (87.2 an ... | 2003 | 12801367 |
| prevalence of tinea capitis in primary schools in turkey. | the aim of our study was to determine the prevalence of tinea capitis in middle anatolia. between february 2000 and april 2000, a school survey of 4760 primary school children was carried out and 34 cases of tinea capitis were clinically diagnosed. sixteen (0.3%) of them were diagnosed both clinically and using culture. eighteen cases (52.9%) were diagnosed microscopically whereas the remaining 16 cases (47.0%) had a clinical diagnose. we also isolated and identified the following species of fun ... | 2003 | 12801366 |
| dermatomycoses in the rijeka area, croatia, before, during and after the war 1990-1999. | the frequency of dermatomycoses as well as the spectrum of causative agents in the rijeka area, northwestern part of croatia, in the periods before and during the war (1990-1994) and in the postwar period (1995-1999) were analyzed. a total of 20 463 patients with clinically suspected dermatomycoses referred to the department of dermatovenerology, clinical hospital center rijeka, was examined. in the period from 1990 till 1994, 2462 samples were positive, compared with 2250 positive samples durin ... | 2003 | 12801365 |
| the prevalence of immediate and delayed type hypersensitivity reactions to microsporum canis antigens in cats. | spontaneous recovery from microsporum canis infections in cats is thought to be dependent on the development of a competent immune response. the purpose of this study was to determine the prevalence of positive delayed type hypersensitivity reactions in cats with and without dermatophytosis. four groups of cats were intradermally skin tested with m canis extract and test sites were evaluated both subjectively and objectively at 0, 24 and 48 h after injection. delayed intradermal testing (idt) re ... | 2003 | 12765626 |
| fluorescent method for studying the morphogenesis and viability of dermatophyte cells. | the dermatophyte microsporum canis is commonly isolated from human and animal infection. the morphogenesis of this fungus was studied during its developmental stages through the fluorescent method fluorescein diacetate and ethidium bromide. to this end, 50 microl dermatophyte suspension were transferred onto cellophane wrapping esterilized discs (2.5 cm of diameter) placed over the surface of sabouraud dextrose agar on petri dishes and incubated at 25 degrees c for 30 days. every 60 minutes duri ... | 2003 | 12733625 |
| effects of lufenuron treatment in cats on the establishment and course of microsporum canis infection following exposure to infected cats. | to determine effects of lufenuron treatment in cats on the establishment and course of microsporum canis infection following exposure to infected cats. | 2003 | 12725307 |
| in vitro antagonistic activity of monoterpenes and their mixtures against 'toe nail fungus' pathogens. | the antibiotic effect of the active ingredients in meijer medicated chest rub (eucalyptus oil, camphor and menthol) as well as the inactive ingredients (thymol, oil of turpentine, oil of nutmeg and oil of cedar leaf) were studied in vitro using the fungal pathogens responsible for onychomycosis, such as the dermatophytes tricophyton rubrum, trichophyton mentagrophytes, microsporum canis, epidermophyton fl occosum and epidermophyton stockdale. the zones of inhibition data revealed that camphor (1 ... | 2003 | 12722144 |
| [clinical and epidemiological survey of dermatophytoses in jaen (spain)] | prevalence of dermatophytosis, with respect to age and sex and dermatophyte species, in jaen was investigated during a period of three years (1996-1999). the prevalence of dermatophytosis over three years was 4.48 cases / 1000 inhabitants. the isolated species were: microsporum canis (48.6%), trichophyton mentagrophytes (27.1%), epidermophyton floccosum (10%), trichophyton rubrum (8.6%), trichophyton violaceum (4.3%), and microsporum gypseum (1.4%). the most frequently observed dermatophytoses w ... | 2002 | 12716229 |
| dermatophytes isolated from symptomatic dogs and cats in tuscany, italy during a 15-year-period. | between january, 1, 1986 and december, 31, 2000, dermatological specimens from 10.678 animals (7.650 cats and 3.028 dogs) were examined for dermatophytes. all the animals presented clinical signs of ringworm. two thousand-four hundred fifty-six of the 10.678 (23%) examined animals scored positive for dermatophytes, 566 out of 3.028 canine (18.7%) and 1890 out of 7.650 feline specimens (24.7%). microsporum canis constituted 83% and 97% of the isolated dermatophytes respectively in dogs and cats, ... | 2002 | 12715942 |
| characteristics of superficial mycoses in malta. | a study was conducted to determine the chief agents of superficial mycoses in malta. data were collected over a 5-year period from mycologic investigations carried out on all dermatologic specimens sent to the mycology laboratory at st. luke's hospital in malta. | 2003 | 12694490 |
| synergistic inhibition of the growth in vitro of microsporum canis by miconazole and chlorhexidine. | an agar dilution technique was used to assess the minimum inhibitory concentrations (mic) of miconazole, chlorhexidine and a 1:1 combination of both agents for 10 isolates of microsporum canis. for nine of 10 of the isolates, a combination of miconazole and chlorhexidine was more effective than either agent alone; fractional inhibitory concentration indices indicated a synergistic effect for five isolates and an additive effect for four. these results illustrate the potent antimycotic effect of ... | 2003 | 12662267 |
| tinea capitis in cleveland: survey of elementary school students. | tinea capitis, a fungal infection of the scalp, is of increasing public health importance, and trichophyton tonsurans has become the primary causative agent in north america. | 2003 | 12582387 |
| fluconazole in the treatment of pediatric tinea capitis caused by microsporum canis. | fluconazole has been shown to be effective in the treatment of fungal scalp infections in children; however, there is limited experience of its use in microsporum scalp infections. we studied 11 children with tinea capitis caused by microsporum canis who received oral fluconazole at a dose of 5-7.5 mg/kg/day for 6 weeks. mycological cure was observed in two of the 11 patients at week 4 from the start of therapy, in four patients at week 8 and in three patients at week 16. one of the remaining pa ... | 2002 | 12512234 |
| in vitro antimicrobial activity of ethanol and water extracts of cassia alata. | crude ethanol and water extract of leaves and barks from cassia alata were tested in vitro against fungi, (aspergillus fumigatus and microsporum canis), yeast (candida albicans) and bacteria (staphylococcus aereus and escherichia coli). c. albicans showed concentration-dependent susceptibility towards both the ethanol and water extracts from the barks, but resistant towards the extracts of leaves. the degree of susceptibility varied, the water extract from barks showed bigger inhibition zone tha ... | 2003 | 12499068 |
| involvement of tnf-alpha changes in human cancer development, prevention and palliative care. | cancer development and ageing are complex sciences. from the study on the process of rodent carcinogenesis, we identified tumor necrosis factor-alpha (tnf-alpha) as an important mediator of cancer development. this paper presents three clinical examples of tnf-alpha up-regulation: by cord factors of mycobacterium tuberculosis, such as trehalose 6-monomycolate, as an activator of protein kinase c and by a cord factor like fraction of microsporum canis obtained in the air inside houses in thailand ... | 2002 | 12470903 |
| fluconazole downregulates metallothionein expression and increases copper cytotoxicity in microsporum canis. | azole antifungals are widely used to treat infections with dermatophyte fungi. whereas it is well established that this class of drugs interferes with fungal ergosterol synthesis, little is known about its potential other biological effects. here we report the isolation and structural organization of microsporum canis metallothionein gene and demonstrate that fluconazole is able to downregulate the baseline as well as copper-induced expression of this gene. since this effect occurred within 30 m ... | 2002 | 12470632 |
| safety and immunologic effects after inoculation of inactivated and combined live-inactivated dermatophytosis vaccines in cats. | to determine antidermatophyte immunologic effects of an experimental combined live-inactivated dermatophytosis vaccine (clidv) and a commercial inactivated dermatophytosis vaccine (idv) in cats and to evaluate adverse effects associated with administration of these vaccines. | 2002 | 12428663 |
| isolation of a microsporum canis gene family encoding three subtilisin-like proteases expressed in vivo. | microsporum canis is the main agent of dermatophytosis in dogs and cats and is responsible for frequent zoonosis. the pathogenesis of the disease remains largely unknown, however. among potential fungal virulence factors are secreted keratinolytic proteases, whose molecular characterization would be an important step towards the understanding of dermatophytic infection pathogenesis. m. canis secretes a 31.5 kda keratinolytic subtilisin-like protease as the major component in a culture medium con ... | 2002 | 12406327 |
| antifungal evaluation of bis mannich bases derived from acetophenones and their corresponding piperidinols and stability studies. | the development of resistance to current antifungal therapeutics drives the search for effective new agents. the fact that some acetophenone-derived mannich bases had shown antifungal activities in our previous studies led us to design and synthesize acetophenone-derived bis mannich bases, b1-b5, bis(beta-aroylethyl)methylamine hydrochlorides, to evaluate their antifungal activity. these bis mannich bases were then converted to the corresponding piperidinols, c1-c5, which are structural isomers ... | 2002 | 12392084 |
| chemical analysis and antifungal activity of the essential oil of calea clematidea. | the chemical composition of the essential oils of calea clematidea baker obtained by hydrodistillation of the leaves and flowers was analysed by gc and gc/ms and the oils were assayed for their antifungal activities. the essential oil of the leaves showed a high content of a new natural epoxy terpenoid, named clemateol (ca. 70 %), with minor amounts of o-vanillin (6.5 %), spathulenol (4.2 %), alpha-terpinene (4.0 %), germacrene b (2.9 %), yomogi alcohol (1.8 %), ( e)-caryophylene (1.7 %), m-cyme ... | 2002 | 12357399 |
| unusual presentation of microsporum canis in human hair. | this study reports an unusual presentation of microsporum canis in infected human hair in a three-year-old boy. infected hairs showed ectothrix colonization with a mass of small conidia and numerous macroconidia typical of the genus microsporum. the infected hairs also showed strong invasion by hyphae bearing small numbers of arthroconidia. these hyphae were thinner and longer than those normally found in hair and scalp. it is well known that in cases of tinea capitis due to m. canis, ectothrix ... | 2002 | 12230223 |
| secreted metalloprotease gene family of microsporum canis. | keratinolytic proteases secreted by dermatophytes are likely to be virulence-related factors. microsporum canis, the main agent of dermatophytosis in dogs and cats, causes a zoonosis that is frequently reported. using aspergillus fumigatus metalloprotease genomic sequence (mep) as a probe, three genes (mep1, mep2, and mep3) were isolated from an m. canis genomic library. they presented a quite-high percentage of identity with both a. fumigatus mep and aspergillus oryzae neutral protease i genes. ... | 2002 | 12228297 |
| survey of dermatophyte infections in the lausanne area switzerland. | the dermatophytes are important in the swiss medical environment since 5-10% of consultations in dermatology concern mycotic infections. | 2002 | 12218248 |
| terbinafine: efficacy and tolerability in young children with tinea capitis due to microsporum canis. | we carried out an open, prospective, uncontrolled study to evaluate the efficacy and tolerability of terbinafine in the treatment of young children with tinea capitis due to microsporum canis. | 2002 | 12195561 |
| [morphological study of human hair infected with microsporum canis]. | some aspects in forensic medical examination of hairs damaged by microsporum canis are discussed. the data of microscopic, fluorescent, and serological studies of damaged hairs and methods for their examination are presented. | 2002 | 12165955 |
| use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes. | the sensititre yeastone antifungal panel was used to test 49 dermatophytes belonging to the species epidermophyton floccosum, microsporum gypseum, microsporum canis, trichophyton tonsurans, trichophyton rubrum, and trichophyton mentagrophytes. the mics of four antifungals obtained with the sensititre yeastone antifungal panel were compared with those obtained by the reference nccls microdilution method. the levels of agreement between the two methods (<or=2 dilutions) were 81.6% with amphoterici ... | 2002 | 12089289 |
| evaluation of the efficacy of oral lufenuron combined with topical enilconazole for the management of dermatophytosis in catteries. | the efficacy of oral lufenuron, a chitin synthetase inhibitor, combined with topical enilconazole, was evaluated for the management of microsporum canis infection in 100 cats housed in two catteries in france. the cats were treated with weekly rinses with enilconazole (0.2 per cent) for four weeks and, in each cattery, one group (a) was also treated with micronised griseofulvin (25 mg/kg administered orally twice a day for five weeks) and a second group (b) was treated with 60 mg/kg lufenuron ad ... | 2002 | 12081306 |
| yeasts of the genus candida are the dominant cause of onychomycosis in libyan women but not men: results of a 2-year surveillance study. | the reported frequency of recovery of fungi from infected nails varies according to the geographical area. | 2002 | 12072073 |
| in vitro susceptibility of microsporum canis and other dermatophyte isolates from veterinary infections during therapy with terbinafine or griseofulvin. | we investigated the in vitro activity of terbinafine against fresh veterinary isolates of microsporum canis and the potential of this organism to develop resistance in vivo during oral therapy. dermatophyte cultures (n = 300) were obtained from naturally infected cats and dogs undergoing oral therapy with terbinafine or griseofulvin. m. canis comprised 92% of isolates; other species included microsporum gypseum and trichophyton mentagrophytes. minimum inhibitory concentrations (mics) and minimum ... | 2002 | 12058731 |
| production of extracellular enzymes by microsporum canis and their role in its virulence. | microsporum canis is the most prevalent dermatophyte of domestic animals. several enzymes produced by dermatophytes, particularly keratinases, are considered to play a role in the virulence of this fungus. to investigate the possible relationship between the clinical status of m. canis infection and enzymatic activity of isolates, we studied the relationship between keratinase, elastase, lipase and dnase levels produced in vitro by different isolates and virulence as expressed in a guinea pig mo ... | 2001 | 12054058 |
| proximal white subungual onychomycosis caused by microsporum canis in systemic lupus erythematosus. | we report the case of a mexican lupus patient who developed proximal white subungual onychomycosis on multiple toenails. microsporum canis was the causative agent. both nail invasion by m. canis and proximal white subungual onychomycosis are rare conditions indicative of an underlying immunodeficiency. | 2002 | 12036214 |
| drug efficacy of terbinafine hydrochloride (lamisil) during oral treatment of cats, experimentally infected with microsporum canis. | cats represent a primary source of microsporum canis infections in humans. terbinafine hydrochloride (lamisil) is commonly used in the treatment of microsporosis in humans as its fungicidal action permits short periods of treatment. the aim of the present study was to estimate the efficacy of the drug in cats. nine cats were experimentally infected with m. canis and treated with terbinafine hydrochloride at a dose of 10-20 mg/kg (once daily, sid; low-dose group, ldg). another nine cats were simi ... | 2002 | 12019941 |
| case report. rosacea-like tinea incognito. | we report a case of dermatophytosis of the face due to microsporum canis that was exacerbated and altered clinically by a long-term application of topical corticosteroids. we considered this case a rosacea-like tinea incognito of the beard area. | 2002 | 12000520 |
| a study of dermatophytoses in sana'a, yemen republic. | the present study describes the extent and causative agents of dermatophytoses in sana'a, the capital of yemen republic. out of 1100 patients with various skin diseases, 16.6% were affected with dermatophytoses. among them, 70% were male and the age group 11-20 years was most susceptible to tinea infections. tinea corporis was the most common disease, followed by tinea capitis. one hundred and seventy isolates of dermatophytes related to 9 species were identified. microsporum canis was the most ... | 2002 | 12000511 |
| dermatophytes and other fungi associated with skin mycoses in tripoli, libya. | this study sought to determine the prevalence of skin infections and their causative agents in the libyan population. samples were collected from 2224 patients attending the dermatology clinics of the tripoli medical centre (tmc) between august 1997 and december 1999 and were submitted to a mycology laboratory for analysis. diagnosis was confirmed by microscopic examination in 1180 cases (53.1%) and the causative agent was isolated and cultured in 1160 cases (52.2%). dermatophytes, malassezia fu ... | 2002 | 12000510 |
| trichophyton violaceum is the dominant cause of tinea capitis in children in tripoli, libya: results of a two year survey. | the causative agents of tinea capitis in libyan nationals attending the out patient dermatology clinic of the tripoli medical centre over the period december 1997 to december 1999 were investigated. samples (hair and scalp scrapings) were taken from 940 patients who presented with suspected tinea capitis. the etiological agents were identified in 584 cases. trichophyton violaceum was found to be the most prevalent organism isolated being responsible for 64.4% (376/584) of culture positive cases, ... | 2002 | 11998877 |
| [fungistatic activity of a sesquiterpene lactone (tomentosin) isolated from fresh inula viscosa (asteraceae) flowers from the puglia region]. | a sesquiterpene lactone, tomentosin, has been isolated and identified form inula viscosá ait (asteraceae) flowers. the molecule, at 1 mg/ml concentration, showed to be active in vitro against microsporum canis, microsporum gypseum and trichophyton mentagrophytes. | 2001 | 11921538 |
| efficacy of oral terbinafine in feline dermatophytosis due to microsporum canis. | microsporum canis is the dermatophyte most commonly responsible for ringworm in cats. the purpose of this paper was to evaluate the in vivo efficacy of oral terbinafine (lamisil; sandoz) in the treatment of feline ringworm caused by m canis, and to consider this drug as an alternative to griseofulvin or imidazoles. fifteen cats infected with m canis were treated orally once daily with 30 mg/kg of terbinafine over a 2-week period. all treated animals were checked for dermatophytes on the last day ... | 1999 | 11919014 |
| synthesis of variously 9,9-dialkylated octahydropyrimido [3,4-a]-s-triazines with potential antifungal activity. | 9,9-dialkyloctahydropyrimido[3,4-a]-s-triazines were synthesized by iminodimethylation reaction between a 5,5-dialkyl-6-aminopyrimidine-2.4(3h,5h)-dione, a substituted aniline and two moles of formaldehyde. the synthesis of.5,5-dialkyl-6-aminopy-rimidinedione consisted of the condensation of urea with ethyl 2,2-dialkylcyanoacetates. 18 octahydropyrimido[3,4-a]-s-triazines were synthesized and compounds resulting from a supplementary aminomethylation were also obtained. most of these compounds we ... | 2002 | 11902652 |
| evaluation of topically applied enilconazole for the treatment of dermatophytosis in a persian cattery. | many persian catteries have long-standing dermatophyte infections and are particularly difficult to treat. enilconazole is a topical antifungal agent that has demonstrated good efficacy in recent studies. twenty-two persian cats naturally infected with microsporum canis in a breeding cattery were treated with topical 0.2% enilconazole and monitored for 180 days. the treatments were repeated every 3 days for a total of eight applications. all the cats improved clinically and became culture negati ... | 2002 | 11896967 |
| [epidemiology and etiology of dermatophytosis in goiânia, go, brazil]. | dermatophytes are a group of closely related fungi that have the capacity to invade keratinized tissue (skin, hair, and nails) of humans and animals to produce infections called dermatophytosis. in order to review the etiology and epidemiology of dermatophytosis in goiânia, go, 1955 specimens with diagnostic suspicion of dermatophytic lesions, were collected from january to december, 1999, from the mycology laboratory in the institute of tropical pathology and public health, federal university o ... | 2002 | 11873256 |
| topical treatment of tinea capitis in a neonate. | tinea capitis is the most common fungal skin infection in children. given that this infection invades the hair shaft and the pilosebaceous unit, systemic antifungal therapy is the gold standard of treatment. despite the neonate's increased susceptibility to infections, tinea capitis is rare in this population. we present the case of a 16-day-old infant with tinea capitis caused by microsporum canis and effectively treated with topical bifonazole 1%. | 2002 | 11868981 |
| case report. tinea corporis due to microsporum canis in a professional cyclist. | we report the case of a 20-year-old man, a professional cyclist, with multiple scaling plaques on his limbs that had been present for 40 days. our case of tinea corporis presented some peculiarities related to the aetiological agent microsporum canis and also its mode of transmission. | 2002 | 11856439 |
| efficacy of itraconazole as a combined continuous/pulse therapy in feline dermatophytosis: preliminary results in nine cases. | this study evaluated the efficacy of itraconazole as a combined continuous/pulse therapy for feline dermatophytosis. nine cats with dermatophytosis caused by microsporum canis were treated with itraconazole at 10 mg kg(-1) orally once daily for 28 days and then on an alternate week regimen (1 week off, 1 week on) at the same dosage. cats were re-evaluated by physical examination and fungal culture at days 28, 42, 56 and 70 if necessary. treatment was stopped when two consecutive negative fungal ... | 2001 | 11844225 |
| itraconazole is effective in the treatment of tinea capitis caused by microsporum canis. | tinea capitis is a relatively common superficial fungal infection in children which requires oral antifungal therapy. in a prospective, open study over 24 weeks, itraconazole 5 mg/kg/day, given as capsules or as an oral suspension for a period of 2-12 weeks, was used to treat children 1-12 years of age who had m. canis tinea capitis. children with mycologic evidence of m. canis tinea capitis were entered into the study and asked to return at week 2 and then every 2 weeks thereafter until cured, ... | 2001 | 11841643 |
| tinea capitis in infants less than 1 year of age. | tinea capitis is the most frequent manifestation of dermatophyte infection in children, but because it is rare in the first months of life it is often misdiagnosed. here we report 15 cases of tinea capitis observed in italy in infants less than 1 year of age. there were 10 boys and 5 girls (mean age 6 months). diagnosis was confirmed by mycologic examination. microsporum canis was isolated in nine cases and trichophyton mentagrophytes in three. these 12 infants were italian and animals were the ... | 2001 | 11841628 |
| synthesis of some 4-(alkylidene/arylidene)amino-2,4-dihydro-5- (2-thienyl)-3h-1,2,4-triazole-3-thiones tested for antimicrobial activity. | a series of 4-(alkylidene/arylidene)amino-2,4-dihydro-5- (2-thienyl)-3h-1,2,4-triazole-3-thiones (2a-h) were synthesized. the structural elucidation of all the compounds was made on the basis of analytical and spectral data (ir, 1h-nmr and eims). all synthesized compounds were evaluated for in vitro antimicrobial activity against various bacteria and fungi. some of the compounds demonstrated antimicrobial activity against staphylococcus aureus atcc 6538, staphylococcus epidermidis atcc 12228, tr ... | 2001 | 11822231 |
| dermatophytoses in prague, czech republic, between 1987 and 1998. | over a 12-year period, from 1987 to 1998, the spectrum of aetiological agents isolated from 11208 patients (6265 females and 4943 males) suspected of having dermatomycosis was analysed in the mycological laboratory of the department of dermatology, charles university, prague. the most frequently examined locations were toenails (34.9%), feet (15.6%), fingernails (12.8%), toe webs (11%), trunk (10%) and hands (8.7%). dermatophytes were isolated from 5605 (30.2%) of all 18528 samples examined. amo ... | 2001 | 11820263 |
| phenotypic characterization of microsporum canis isolated from cats and dogs. | to characterize strains of microsporum canis that infect dogs and cats in são paulo city, 30 isolates of this dermatophyte were tested for their ability to assimilate carbon and nitrogen sources, for proteinase and phospholipase secretion, for susceptibility to yeast killer toxins, and for susceptibility to the antifungals fluconazole, ketoconazole, itraconazole, 5-fluorocytosine and amphotericin b, in e test. all samples assimilated the nitrogen sources asparagine, ammonium sulphate, urea and s ... | 2001 | 11820261 |
| further evaluation of rwandan medicinal plant extracts for their antimicrobial and antiviral activities. | a total of 45 rwandan plant extracts, belonging to 37 different plant species out of 21 families, were investigated for their antibacterial, antifungal, and antiviral properties. the plants were selected on the base of their ethnomedicinal use against infections and autoimmune diseases. from all the plant extracts tested, only clematis hirsuta (leaves) showed a pronounced antifungal activity against candida albicans and the dermatophytes trichophyton rubrum, epidermophyton floccosum, and microsp ... | 2002 | 11801376 |
| tinea cruris due to combined infections of trichophyton mentagrophytes and microsporum canis. a case report. | 2001 | 11800157 | |
| tinea capitis in adults during 1981-95 in northern greece. | the mycological laboratory of our hospital examined 31,073 patients between 1981 and 1995. sex, age, the residence of patients, the clinical type of tinea and contacts with other persons and animals were investigated. all the patients were also examined under wood's light. tinea capitis was diagnosed in 35 adults. trichophyton violaceum was the commonest aetiological agent (54.5%), especially in elderly women. the other anthropophilic fungi were t. rubrum (8.5%), t. schoenleinii (5.7%) and t. to ... | 2001 | 11766106 |
| determination of terbinafine hydrochloride in cat hair by two chromatographic methods. | terbinafine hydrochloride (terbhcl) concentration on the site of infection with microsporum canis is a very important indicator of drug effectiveness. several chromatographic methods exist that can be used for the determination of terbhcl concentration in biological samples. a high performance liquid chromatographic (hplc) method and a gas chromatographic (gc) method have been compared and critically evaluated for the determination of a terbhcl levels in cat hair. the sensitivity and the lineari ... | 2001 | 11748682 |
| pseudomycetoma caused by microsporum canis in a persian cat: lack of response to oral terbinafine. | an eight-year-old neutered female persian cat with a four-year history of relapsing skin disease, characterised by ulcerated nodules with a yellow granular discharge, was examined. a diagnosis of granulomatous dermatitis and panniculitis (pseudomycetoma) caused by microsporum canis was made on the basis of history, clinical signs, histopathological examination of skin biopsy specimens and culture of macerated tissue. because previous therapy, comprising repeated surgical excision and the adminis ... | 2001 | 11721986 |
| a study of the efficacy of topical and systemic therapy for the treatment of feline microsporum canis infection. | microsporum canis infection was induced in 21 healthy spf-derived cats. once infection was established (4 weeks after inoculation) the cats were divided into three equal groups housed in separate rooms and monitored for 16 weeks. during this time, group a cats received oral griseofulvin at approximately 50 mg/kg daily and were shampooed twice weekly with a product containing chlorhexidine and miconazole. group b cats were treated with griseofulvin alone, and group c cats served as untreated cont ... | 2000 | 11716608 |
| [an epidemiological study for fungus isolation during the twenty-five year periods from 1976 to 2000 in kitasato university hospital]. | we investigated an epidemiological study for fungus isolation in our hospital from 1976 to 2000. for 25 years, the total sample number of fungus examination were 64,296, and after 1988, the total sample number increased suddenly. as a whole, the positive ratio was constantly about 40%. when our hospital opened, the obstetrical and gynecological samples showed 38.8% for fungus examination, but recently, samples of the respiratory organ has increased. ratio of isolation for yeast, candida albicans ... | 2001 | 11712361 |
| tinea capitis in europe: new perspective on an old problem. | a survey of tinea capitis conducted under the auspices of the european confederation of medical mycology showed that laboratories contributing to a voluntary scheme for reporting have recently been seeing a different pattern of scalp ringworm. the survey was conducted among 92 medical mycology laboratories across 19 european countries by postal questionnaire comparing the years 1987 with 1997. the survey shows an overall increase in the numbers of cases caused by anthropophilic infections, which ... | 2001 | 11683286 |
| doubled dose of oral terbinafine is required for microsporum canis tinea capitis. | fourteen children, ages 1-15 years, with microsporum canis tinea capitis were given oral terbinafine for 4 weeks at the recommended daily dose according to their weight: 10-20 kg, 62.5 mg; 20-40 kg, 125 mg; > 40 kg, 250 mg. because none of the patients had clinically responded to treatment by week 4 the dose of terbinafine was doubled (up to 250 mg) for an additional 4-8 weeks in six patients, and continued at the original dose in six patients. two patients dropped out of the study. on final eva ... | 2001 | 11576412 |
| terbinafine hydrochloride treatment of microsporum canis experimentally-induced ringworm in cats. | cats represent the most important source of microsporum canis infection to people. terbinafine hydrochloride is commonly used in the treatment of microsporosis. its fungicidal action permits short period of treatment. it was our objective to evaluate the effectiveness of this drug in treatment of microsporosis in cats. we treated nine experimentally m. canis infected cats with terbinafine at a dose of 10-20mg/kg sid (low-dose group, ldg), nine cats with 30-40mg/kg sid (high-dose group, hdg), and ... | 2001 | 11557156 |
| cutaneous xanthomas with concurrent demodicosis and dermatophytosis in a cat. | multiple cutaneous xanthomas, associated with fasting hyperlipidaemia, are described in a 9-month-old domestic long-haired cat. a severely pruritic, papular, and crusting dermatitis affecting the head and neck, initially diagnosed as lesions of the eosinophilic granuloma complex, progressively developed on the head and pinnae. pruritus was controlled with administration of prednisolone and chlorambucil. repeat histological examination confirmed the diagnosis of cutaneous xanthoma and concurrent ... | 2001 | 11549045 |
| application of pcr to distinguish common species of dermatophytes. | this report describes the application of pcr fingerprinting for the identification of species and varieties of common dermatophytes and related fungi utilizing as a single primer the simple repetitive oligonucleotide (gaca)(4). the primer was able to amplify all the strains, producing species-specific profiles for microsporum canis, microsporum gypseum, trichophyton rubrum, trichophyton ajelloi, and epidermophyton floccosum. intraspecific variability was not observed for these species. instead, ... | 2001 | 11526185 |
| expression of ubiquitin gene in microsporum canis and trichophyton mentagrophytes cultured with fluconazole. | the expression of the ubiquitin (ub) gene in dermatophytes was examined for its relation to resistance against the antifungal drug fluconazole. the nucleotide sequences and the deduced amino acid sequences of the ub gene in microsporum canis were proven to be 99% similar to those of the ub gene in trichophyton mentagrophytes. expression of mrna of ub in m. canis and t. mentagrophytes was enhanced when the fungi were cultured with fluconazole. the antifungal activity of fluconazole against these ... | 2001 | 11502529 |
| two cases of dermatophytic pseudomycetoma in the dog: an immunohistochemical study. | two cases of canine dermatophytic pseudomycetoma resulting in subcutaneous nodules resembling those previously reported in persian cats are described. culture performed from one nodule yielded dark yellow colonies consistent with microsporum canis. immunohistochemistry, using rabbit anti-m. canis, demonstrated specific binding to fungal elements in paraffin sections. the specificity of the antiserum was further tested by an agar gel immunodiffusion assay using a soluble extract from a feline iso ... | 2001 | 11493404 |
| hair and scalp mycobiota in school children in nablus area. | hair and scalp mycobiota of 1389 clinically normal children aged 6-12 years attending 12 schools in the nablus district, palestinian authority, was assessed on three occasions over 8-month period (october 1998-may 1999) using the hair brush technique. one hundred and one fungal species belonging to 33 genera were recovered: 6 dermatophytes, 16 dermatophyte-like keratinophilic fungi, and 79 other keratinophilic fungal species. species varied considerably in their frequency of occurrence and abund ... | 2001 | 11469760 |
| purification and characterization of a 43.5 kda keratinolytic metalloprotease from microsporum canis. | a keratinolytic protease secreted by a feline clinical isolate of microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by affinity chromatography on bacitracin-agarose and by hydrophobic chromatography on octyl-agarose. the enzyme had an apparent molecular mass of 43.5 kda and the pi was 7.7. it had a significant activity against keratin azure, elastin-congo red and denatured type i collagen (azocoll). using the latt ... | 2001 | 11446530 |
| evaluation of the dermatophyte test medium rapidvet-d. | the performance of the dermatophyte test medium (dtm) rapidvet-d was assessed using hair samples collected from experimentally infected guinea pigs. three dermatophyte species were included in the study: microsporum canis, trichophyton mentagrophytes and trichophyton equinum. dtm substrates were inoculated with infected hairs and scales, incubated at 18, 21, 24, 27 or 37 degrees c and examined daily for 15 days. the rapidity of colour change was clearly related to the incubation temperature and ... | 2001 | 11420927 |
| effectiveness of terbinafine in the eradication of microsporum canis from laboratory cats. | in this study, the coats of 20 cats with no dermatophytosis lesions were sampled for colonization by microsporum canis, which was isolated in 45% of cases. all cats were treated with oral terbinafine for 3 weeks. the drug was administered orally at a daily dosage 8.25 mg kg-1. mycologic status was assessed at the end of the treatment; and after follow-up at 2 days, and 4 and 9 weeks. the final evaluation revealed a complete mycologic cure of all cats by obtaining negative cultures, thereby demon ... | 2001 | 11413930 |
| case report. onychomycosis due to microsporum canis. | a case of distal subungual onychomycosis of the big toe due to microsporum canis is reported in a 69-year-old male asthma patient who had been treated with systemic corticosteroids for the last 3 years. the nail infection was contracted from a cat who was a healthy carrier. the patient was treated successfully with intermittent itraconazole therapy. | 2001 | 11413924 |
| oral terbinafine for tinea capitis due to microsporum canis in children. | 2001 | 11411922 | |
| antifungal activity of modified hederagenin glycosides from the leaves of kalopanax pictum var. chinense. | monodesmosides which were obtained from the partial degradation of hederagenin bisdesmosides exhibited significant antifungal effect against microsporum canis, coccidioides immitis, trichophyton mentagrophytes, cryptococcus neoformans, and candida albicans at the minimal inhibitory concentrations of 6.25-25 microg/ml. the hederagenin glycosides were isolated from the leaves of kalopanax pictum var. chinense. | 2001 | 11411568 |
| the aetiological agents of tinea capitis in zaragoza (spain). | between 1977 and 1997, 190 cases of tinea capitis were observed. the age groups most commonly infected were 1-10 years old. the following dermatophytes were isolated: microsporum canis (119), trichophyton mentagrophytes (57), trichophyton tonsurans (seven), trichophyton verrucosum (three), trichophyton violaceum (one), trichophyton schoenleinii (one), trichophyton soudanense (one) and microsporum audouinii (one). | 2001 | 11398641 |
| a case of feline otitis externa due to microsporum canis. | we describe a case of a 3-month-old persian male cat with a persistent waxy, ceruminous, otic discharge in both external auditory canals. after microbiological culture, only microsporum canis was isolated with no concurrent fungal or bacterial flora. fungal otitis due to dermatophytes was diagnosed and specific treatment with griseofulvin was administered. after 4 weeks of treatment, no m. canis colonies were isolated and clinical recovery had occurred. in view of this case, dermatophytosis shou ... | 2001 | 11346273 |
| a specific pcr assay for the dermatophyte fungus microsporum canis. | a dna fragment of approximately 1.2 kb, generated from the common dermatophyte microsporum canis by arbitrarily primed polymerase chain reaction (pcr) using random primer opu13, was cloned and sequenced. based on the resulting sequencing data, a forward primer (mc1f) and a reverse primer (mc1r) have been designed and assessed by pcr for their usefulness in the improved identification of m. canis. the results obtained suggest that these primers are specific for m. canis, as a band of 900 bp was a ... | 2001 | 11346271 |
| tinea capitis: study of asymptomatic carriers and sick adolescents, adults and elderly who live with children with the disease. | tinea capitis is a dermatophyte infection that occurs mainly in childhood; there are few reports, in brazil, in adolescents and adults. the detection of asymptomatic carriers is of great importance in the disease control. from february 1998 to february 1999, a study was performed at the outpatient dermatologic unit of instituto de puericultura e pediatria martagão gesteira (universidade federal do rio de janeiro, brasil) to verify the frequency of asymptomatic carriers and tinea capitis between ... | 2001 | 11340482 |
| dermatophytoses in children: study of 137 cases. | dermatophytoses are common fungal infections caused by dermatophytes but there are few data about this condition in the childhood. 137 children below the age of 12 and clinically diagnosed as tineas were investigated prospectively at instituto de puericultura e pediatria, rio de janeiro, from 1994 to 1999. hair, skin/nails scraping and pus swabs were collected from lesions and processed for fungus. male children from 2 to 12 years were mostly affected; tinea capitis (78 cases) mainly caused by m ... | 2001 | 11340481 |
| [advances in molecular biology of dermatophytes]. | during the 44th meeting of the japanese society for medical mycology in nagasaki, 2000, a forum was held entitled advances in molecular biology of dermatophytes. based on the subject, target molecules and kind of approach, we selected seven presentations from over 100 of the poster abstracts. six of them concerned identification and one concerned viability. summaries of the 7 presentations are given in this article. of presentations on the identification methods, 5 demonstrated their usefulness: ... | 2001 | 11331468 |
| tinea capitis in two elderly women: transmission at the hairdresser. | tinea capitis is rare in the elderly. we report cases of two elderly women who presented to our dermatology clinic within 8 weeks of each other, with scalp scaling and alopecia. in both cases, microsporum canis grew on fungal culture of their hair, and required prolonged treatment with terbinafine. neither of them gave a history of contact with young children or any animals. both were fairly fit and not systemically immunocompromised. however, both had been regularly visiting the same hairdresse ... | 2001 | 11298558 |
| antifungal activity of some mono, bis and quaternary mannich bases derived from acetophenone. | the development of resistance to current antifungal therapeutics drives search for new effective agents. some mannich bases have antifungal activity, but no information is available regarding the antifungal activity of acetophenone derived mannich bases. mono mannich bases of acetophenone 1-3 were synthesized and converted into their corresponding bis derivatives, 5-7. representative quaternary derivatives 4 and 8 were also synthesized. antifungal activities of the compounds were evaluated using ... | 2001 | 11215330 |
| microsporum canis tinea capitis in an 8-month-old infant successfully treated with 2 weekly pulses of oral itraconazole. | we report an 8-month-old girl with tinea capitis caused by microsporum canis which was successfully treated with two pulses of oral itraconazole 50 mg/day, each of 1 week duration with an interval of 2 weeks. m. canis tinea capitis can be a difficult therapeutic problem in an infant, as the treatment is usually long, lasting up to 4-6 weeks with griseofulvin and 6-12 weeks with terbinafine, and the desire to provide a safe systemic therapy is particularly important. with an intermittent regimen ... | 2001 | 11207976 |
| [urban and rural mycozoonoses]. | the main mycozoonoses are due to specific dermatophytes which are pathogens for man and animals. contamination occurs most often after close contact with the animal showing clinical lesions or with inapparent carriage only. the contaminated environment also participates to the mycozoonotic epidemics. interhuman transmission is more rarely encountered. young children before puberty are most receptive to the disease. the main urban mycozoonosis is due to microsporum canis transmitted by dogs and c ... | 2000 | 11195712 |
| tinea faciei due to microsporum canis abscess formation. | superficial dermatophyte infections are common in children; however, complications are encountered rarely. we describe a child with tinea faciei caused by microsporum canis, who subsequently developed an abscess. complete resolution occurred after treatment with oral terbinafine. | 2000 | 11167972 |
| [molecular biological methods and their consequences in taxonomy and diagnosis of dermatophytes]. | trichophyton rubrum, t. mentagrophytes, t. verrucosum, microsporum canis, m. gypseum and epidermophyton flocoosum represent the cause of human dermatomycoses isolated most often at the university hospital of dermatology in graz, austria, between 1991 and 1998. so far, identification was mainly based on the cultivation of fungal isolates on special media as well as on the analysis of their microscopic characters. restriction enzyme length polymorphisms (rflps) were now used to identify these huma ... | 2000 | 11098620 |
| [epidemiology, clinic and treatment of dermatomycoses caused by zoophilic dermatophytes] . | in the last 50 years the spectrum of agents of dermatophytoses changed. the change is remarkable especially in the case of zoophilic dermatophytes. microsporum canis has displaced trichophyton verrucosum. in the period from 1966 to 1970 2822 dermatophytoses were registered as occupational dermatoses in the former german democratic republic. in the following years the number of these diseases was continuously reduced, between 1981 and 1985 down to 995 cases. this reduction is predominantly the re ... | 2000 | 11098618 |
| optimizing the therapeutic approach in tinea capitis of childhood with itraconazole. | tinea capitis is the most common dermatophytosis of childhood with increasing incidence. whereas griseofulvin is considered by many as the mainstay of treatment, newer oral antifungal agents, including fluconazole, itraconazole and terbinafine have demonstrated higher efficacy, resulting in shorter treatment durations. | 2000 | 11069511 |
| [dermatophytoses due to domestic animals]. | dermatophytoses are superficial skin infections due to dermatophytes which are filamentous fungi. some dermatophytes can be hosted by domestic animals. in belgium, microsporum canis, trichophyton (t.) mentagrophytes variety mentagrophytes, t. verrucosum and t. equinum are zoophilic species capable of infecting humans. animals, clinical aspects in humans and the investigations needed will be reviewed. treatment should target animal and patient but also limit the spread of the infection. topical t ... | 2000 | 11068472 |
| characterization of an extracellular keratinase from microsporum canis. | extracellular keratinase (ekase) 48-, 34- and 31.5-kda polypeptides, which were isolated from microsporum canis and examined by immunoblotting reacted with a monoclonal antibody against ekase of m. canis. we analyzed the amino acid and determined the first 17 amino acid nh2-terminal sequences of the 48-, 34- and 31.5-kda polypeptides. these polypeptides had a high aspartic acid, glycine and alanine content, respectively. the first 17 amino acid residues of the 34-kda polypeptide were homologous ... | 2000 | 11064325 |
| [microsporum canis mycetoma of the scalp]. | mycetoma is a chronic subcutaneous tumefaction with presence of grains or granules. etiological agents include bacteria or filamentous fungi. mycetoma due to dermatophytes is uncommon, mainly occurring in africa. to our knowledge, no case has been reported in the west indies. only two observations of micosporum canis mycetoma in humans have been reported in the literature. we report a third case of mycetoma of the scalp caused by this fungus. | 2000 | 11011164 |
| the development of the method for the determination of terbinafine in cat's plasma and hair. | clinical investigations of terbinafine indicate its high treatment activity against infections by several dermatophytes. its efficiency was tested also in the treatment of microsporosis in cats. the distribution of terbinafine in cat's plasma and hair is important for the identification of the drug efficiency. a fast and reliable reversed-phase high performance liquid chromatographic method with appropriate sample preparation has been developed. reliability, good reproducibility and low detectio ... | 2000 | 11005657 |
| nosocomial ringworm in a neonatal intensive care unit: a nurse and her cat. | an outbreak of nosocomial ringworm involved five infants in a neonatal intensive care unit. the index case was a nurse infected with microsporum canis by her cat. after standard infection control measures were initiated, the outbreak was resolved successfully by an interdisciplinary professional collaboration of physician and veterinary dermatologists and infection control personnel. | 2000 | 11001268 |
| detection of microsporum canis in the skin scrapings and hairs of dogs with dermatophytosis based on sequences of the chitin synthase 1 gene. | in the present study, to confirm microsporum canis infection rapidly, we detected the chitin synthase gene 1 (chs1) gene of m. canis in the hair and skin samples of four dogs with dermatophytosis. amplification of the dnas in the four samples with chs1 primers yielded fragments of about 620-bp. nucleotide sequence analysis of the chs1 gene fragments from samples and a reference strain of m. canis gene showed more than 99% similarity. the method presented in this study can rapidly detect the dna ... | 2000 | 10981834 |
| tinea capitis. | tinea capitis is a common dermatophyte infection of the scalp in children. dermatophytes are classified into three genera; tinea capitis is caused predominantly by trichophyton or microsporum species. on the basis of host preference and natural habitat, dermatophytes are also classified as anthropophilic, geophilic and zoophilic. the etiological agents of tinea capitis usually fall in the first and last categories. in north america, tinea capitis is now predominantly due to trichophyton tonsuran ... | 2000 | 10975696 |
| microsporum canis associated with otitis externa in a persian cat. | 2000 | 10955895 | |
| antifungal effects of hydrolysable tannins and related compounds on dermatophytes, mould fungi and yeasts. | a series of hydrolysable tannins and related compounds was evaluated for antifungal activities against filamentous fungi (epidermophyton floccosum; microsporum canis; microsporum gypseum; trichophyton mentagrophytes; trichophyton rubrum; trichophyton tonsurans; trichophyton terrestre; penicillium italicum; aspergillus fumigatus; mucor racemosus; rhizopus nigricans) and opportunistic yeasts (candida albicans; candida glabrata; candidata krusei; cryptococcus neoformans), using the agar dilution me ... | 2000 | 10928561 |