Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| nutritional quality and the presence of anti-nutritional factors in leaf protein concentrates (lpc). | leaf protein concentrates were prepared from 25 different plant species. the concentrates contained acceptable levels of all essential amino acids; except methionine which was limiting with chemical scores ranging between 13.5-96%. lpcs from sesbania, nebergrass, lufa and sweet pepper were lethal to the rats. per ranged between 0.28 for safflower lpc up to 1.95 for rape. positive nitrogen balance was obtained with diets based on lpcs with mean values ranging between 6.4 and 22.42 mg n per day. t ... | 1999 | 10719564 |
| isolation and characterization of mitochondrial manganese superoxide dismutase (mnsod) from capsicum annuum l. | a cdna clone for a mitochondrial manganese superoxide dismutase (mnsod) was isolated and characterized from red pepper (capsicum annuum l.). the clone consisted of 941 bp containing one open reading frame (orf) of 687 bp, 34 bp/220 bp of 5'/3'-untranslated region. amino acid sequence of the orf showed the highest homology (86%) with that of nicotiana plumbaginifolia. it encodes for a polypeptide of 228 amino acids with a molecular mass of 25.5 kda and a pi value of 8.39. genomic southern hybridi ... | 1999 | 10672929 |
| evaluation of the efficacy of the crude extracts of capsicum frutescens, citrus limon and opuntia vulgaris against newcastle disease in domestic fowl in tanzania. | prophylactic and therapeutic efficacy of a combination of capsicum frutescens (red pepper), citrus limon (lemon) and opuntia vulgaris (prickly pear) against newcastle disease (nd) in domestic fowl were evaluated. eighty-eight broiler chickens were divided into five groups. birds from three groups were inoculated with velogenic nd virus strain, whereas birds from two groups were left as controls. two groups received a mixture of the plant extract three days prior to inoculation and birds from one ... | 1999 | 10624862 |
| lipid peroxidation and the oxidative burst associated with infection of capsicum annuum by botrytis cinerea | a combination of electron paramagnetic resonance (epr) spectroscopy and analytical chemistry has been used to study the changes in free radical content, transition metal ion status and lipid peroxidation following inoculation of fruits of sweet pepper (capsicum annuum) with botrytis cinerea. epr detected a high concentration of an unidentified free radical associated with the spreading lesion that extends into the surrounding, healthy tissues. in addition, the epr-detectable iron(iii) was highes ... | 1999 | 10607300 |
| latex type i sensitization and allergy in children with atopic dermatitis. evaluation of cross-reactivity to some foods. | recent studies have demonstrated that allergy to natural rubber latex (nrl) is associated with cross-reactivity to certain foods. the aim of this study was to investigate the prevalence of nrl sensitization and allergy in children with atopic dermatitis (n=74). we also examined cross-reactions between latex and foods, and compared the frequency of suspected latex cross-reacting fruits in children with and without nrl-specific immunoglobulin e (ige). twelve of the 74 atopic children studied (16.2 ... | 1999 | 10565556 |
| effects of roasting on pyrazine contents and oxidative stability of red pepper seed oil prior to its extraction. | red pepper seeds were roasted with constant stirring for 6, 9, 10, and 12 min at 210 degrees c, and oils were extracted from the roasted red pepper seeds using an expeller. the iodine values and fatty acid compositions of red pepper seed oils did not change with roasting time. the fatty acid composition of the oil obtained from the red pepper seeds roasted for 6 min was 0.24% myristic acid, 13. 42% palmitic acid, 0.33% palmitoleic acid, 2.07% stearic acid, 10. 18% oleic acid, 73.89% linoleic aci ... | 1999 | 10564041 |
| 2,4-nonadienal and benzaldehyde bioantimutagens in fushimi sweet pepper (fushimi-togarashi). | fushimi sweet pepper, "fushimi-togarashi", is one of the "kyo-yasai", traditional vegetables, in kyoto, japan. the chloroform fraction of fushimi sweet pepper showed bioantimutagenicity on uv induced mutation in escherichia coli b/r wp2. the bioantimutagen was purified with silica gel chromatography and identified as 2, 4-nonadienal (id(50) = 20 microg/plate) on the basis of gc retention time and ei-ms spectrum of authentic 2,4-nonadienal. the sweet pepper also contained a known bioantimutagen, ... | 1999 | 10563930 |
| change in the carotenoid and antioxidant content of spice red pepper (paprika) as a function of ripening and some technological factors. | a study was conducted to investigate the change in quality attributes of red pepper (paprika) (capsicum annuum l. var. km-622) as a function of ripening and some technological factors. of quality attributes, carotenoids and bioantioxidants (ascorbic acid and tocopherols) have been studied. it was found that the dynamics of fruit ripening with regard to carotenoids and bioantioxidants was influenced to a considerable extent by weather conditions of the production season. a rainy and cool season y ... | 1999 | 10563856 |
| study of lability and kinetics of the main carotenoid pigments of red pepper in the de-esterification reaction. | different concentrations of potassium hydroxide in methanol were used to control the time required for complete de-esterification of the carotenoids present in paprika oleoresin, and the effectiveness of the overall process was determined. with concentrated solutions of potash, 20% and 30% (w/v), the reaction was completed in a shorter time but the overall process was less effective. solutions of low concentration, 5% and 10% (w/v), enabled the kinetic study to be carried out and the rates of de ... | 1998 | 10554278 |
| capsaicin induces cystatin s-like substances in submandibular saliva of the rat. | irritating dietary substances such as tannin and papain have been reported to alter the morphology of salivary glands and their secretions. such alterations can be one line of protection from toxic or irritating substances in food. we investigated the effects of dietary capsaicin (a pungent ingredient of hot red pepper) on the rat submandibular gland and its secretions. several groups of animals were offered either control diets or diets containing capsaicin (from 0.0001 to 0.1%) for seven days. ... | 1999 | 10520965 |
| modulation of intestinal functions by food substances. | the small intestinal epithelium plays a crucial role in the digestion/modification of food components, absorption of nutrients and recognition of food-derived signals. it also acts as a barrier against unfavourable materials in food. these intestinal functions may be influenced by food substances. in this paper, the effects of various food substances on the intestinal functions, particularly the absorption functions, are discussed. a new assay method, using a monolayer culture system of human in ... | 1999 | 10399347 |
| [effect of green vegetable on digestive tract absorption of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in rats]. | the effect green vegetable on fecal excretion of polychlorinated dibenzo-p-dioxin (pcdd) congeners and polychlorinated dibenzofuran (pcdf) congeners was examined in male rats. the rats were administered 10% vegetable diets or a basal diet containing 0.2 ml of the causal rice-bran oil of yusho that had occurred in the southwest part of japan in 1968 and kept on the same diet for five days. the fecal excretion of 2,3,7,8-t4cdd and 2,3,4,7,8-p5cdf in the group fed with komatsuna, mitsuba, spinach a ... | 1999 | 10396873 |
| determinants of salt use in cooked meals in the netherlands: attitudes and practices of food preparers. | to assess current habits of using salt and other seasonings in food preparation, and to investigate the psychosocial determinants of salt use. in addition we examined differences in salt consumption and psychosocial determinants with respect to stages of change and socio-economic classes. | 1999 | 10369495 |
| effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in japanese women. | the effects of dietary red pepper added to high-fat (hf) and high-carbohydrate (hc) meals on energy metabolism were examined in thirteen japanese female subjects. after ingesting a standardized dinner on the previous evening, the subjects took an experimental breakfast (1883 kj) under the following four conditions: hf meal, hf and red-pepper (10 g) meal, hc meal, or hc and red-pepper meal. palatability of the experimental meals was measured immediately after the meals. expired air was collected ... | 1998 | 10211048 |
| lack of tumor promoting activity of capsaicin, a principal pungent ingredient of red pepper, in mouse skin carcinogenesis. | capsaicin (trans-8-methyl-n-vanillyl-6-nonenamide) is the major pungent principle of hot peppers of the genus capsicum. there have been numerous investigations to evaluate the effects of capsaicin on experimental carcinogenesis and mutagenesis, but the results are discordant. in the present study, we have assessed the tumor promoting potential of capsaicin using a two stage mouse skin carcinogenesis model. repeated applications of capsaicin (10 mumol) onto the shaven backs of female icr mice fol ... | 1998 | 9891468 |
| cross-reactivity between latex and sweet pepper due to prohevein. | 1998 | 9821486 | |
| [is there a correlation between dietary habits and hemorrhoidal disease?]. | it is empirically accepted that certain foods play a role in the pathogenesis of hemorrhoids or their acute exacerbation. the aim of this work was to determine whether there is a relationship between hemorrhoids and certain food-related or common toxin-related factors. | 1998 | 9767961 |
| protective effects of fruits and vegetables against in vivo clastogenicity of cyclosphosphamide or benzo[a]pyrene in mice. | seven fruits and 10 vegetables commonly consumed in germany were investigated for their anticlastogenic potencies against cyclophosphamide (cp) and benzo[a]pyrene (bap) in the in vivo mouse bone marrow micronucleus assay. we detected protective effects in 76.5% and 70.6% of the samples, respectively, and more or less distinct quantitative differences between the various plant materials and the two clastogens investigated. with respect to cp, moderate activities were exerted by sweet cherries, st ... | 1998 | 9734714 |
| vegetable and fruit consumption and prostate cancer risk: a cohort study in the netherlands. | the association between 21 vegetables and eight fruits and prostate cancer risk was assessed in the netherlands cohort study among 58,279 men of ages 55-69 years at baseline in 1986. after 6.3 years of follow-up, 610 cases with complete vegetable data and 642 cases with complete fruit data were available for analysis. in multivariate case-cohort analyses, the following rate ratios (rrs) and 95% confidence intervals (cis) for vegetable consumption were found (comparing highest versus lowest quint ... | 1998 | 9718219 |
| inhibition of listeria monocytogenes and aeromonas hydrophila by plant extracts in refrigerated cooked beef. | refrigerated ready-to-eat foods are becoming increasingly popular but are often vulnerable to contamination and subsequent growth by psychrotrophic foodborne pathogens. consequently, there is a need for additional methods to assure the safety of these foods. beef slices prepared from roasted whole sirloin tips were used in the study. nine plant extracts were evaluated for ability to inhibit the growth of two psychrotrophic pathogens (aeromonas hydrophila and listeria monocytogenes) in refrigerat ... | 1998 | 9708301 |
| chemoprotective properties of some pungent ingredients present in red pepper and ginger. | there has been a substantial body of data, supporting that dietary factors have a profound impact on prevention as well as etiology of human cancer. capsaicin has been tested by many investigators for its effects on experimental carcinogenesis and mutagenesis. data in the literature indicate that capsaicin has dual effects on carcinogenic and mutagenic processes. at present, there is no solid evidence that hot red and chili peppers or their principal pungent ingredient capsaicin are carcinogenic ... | 1998 | 9675305 |
| effect of pepper and bismuth subsalicylate on gastric pain and surface hydrophobicity in the rat. | the mechanism by which dietary pepper causes dyspepsia and epigastric pain is poorly understood, as is the ability of bismuth subsalicylate (bss) to relieve these symptoms. | 1998 | 9663730 |
| in vitro antimutagenic and in vivo anticlastogenic effects of carotenoids and solvent extracts from fruits and vegetables rich in carotenoids. | the water insoluble residues of some carotenoid-rich fruits and vegetables, such as apricots, oranges, brussels sprouts, carrots, yellow-red peppers, and tomatoes, were sequentially extracted with n-hexane, dichloromethane, acetone, and 2-propanol, and solvent extracted materials were tested for inhibition of mutagenicities induced by aflatoxin b1 (afb1), benzo[a]pyrene (bap), 2-amino-3-methylimidazo[4,5-f]quinoline (iq), and cyclophosphamide (cp) in histidine-deficient strains of salmonella typ ... | 1998 | 9639691 |
| effect of capsaicin-containing red pepper sauce suspension on upper gastrointestinal motility in healthy volunteers. | afferent nerves play a major role in the regulation of gastrointestinal motility. the questions remains if specific food ingredients can selectively activate such fibers. the aim of the study was to investigate the effect of intraesophageal application of a capsaicin-containing red pepper sauce (tabasco) suspension on upper gastrointestinal motility in a controlled trial. after a baseline recording [esophageal motility, balloon distension, electrogastrogram (egg)], red pepper or saline solution ... | 1998 | 9635602 |
| recent advances in understanding of vanilloid receptors: a therapeutic target for treatment of pain and inflammation in skin. | c-fiber sensory afferent neurons, which contain neuropeptides such as calcitonin-gene related peptide and substance p, mediate a wide variety of physiologic responses, including chemogenic pain, thermoregulation, and neurogenic inflammation. capsaicin, the pungent constituent in red pepper, functions to activate and then, at higher doses and longer times, desensitize this class of neurons. this latter response provides the basis for the therapeutic application of capsaicin. a major advance in th ... | 1997 | 9487017 |
| food intake, energy balance and body weight control. | obesity is a multifactorial and complex affectation that is characterized by a long-term excess energy intake (ei) above energy expenditure (ee). since fat oxidation seems to be dependent on sns activation and also seems to remain acutely unaffected by fat intake, this macronutrient is certainly partly responsible for this situation. in addition, high-fat intake does not induce as potent satiety signals or a compensation effect on subsequent ei as do diets rich in carbohydrates or proteins. more ... | 1997 | 9426360 |
| effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages. | the inflammatory mediators secreted by macrophages play an important role in autoimmune diseases. spice components, such as curcumin from turmeric and capsaicin from red pepper, are shown to exhibit antiinflammatory properties. the influence of these spice components on arachidonic acid metabolism and secretion of lysosomal enzymes by macrophages was investigated. rat peritoneal macrophages preincubated with 10 microm curcumin or capsaicin for 1 h inhibited the incorporation of arachidonic acid ... | 1997 | 9397403 |
| isolation and characterization of cytosolic copper/zinc superoxide dismutase from capsicum annuum l. | a cdna clone for a cytosolic cu/zn superoxide dismutase (cu/znsod) was isolated and characterized from red pepper (capsicum annuum l.). the clone consisted of 735 bp containing one open reading frame (orf) of 459 bp, 46 bp of 5'- and 230 bp of 3'-untranslated region. the nucleotide sequence of the orf showed 93% homology with that of nicotiana plumbaginifolia and tomato. it encodes a polypeptide of 154 amino acids with a molecular weight of 15,300. genomic southern hybridization suggested that o ... | 1997 | 9387156 |
| increase in swimming endurance capacity of mice by capsaicin-induced adrenal catecholamine secretion. | increase in endurance swimming capacity caused by capsaicin (cap), a pungent component of red pepper, -induced increase of fat metabolism in mice was investigated using an adjustable-current water pool. the mice administered cap via a stomach tube, showed longer swimming time until exhaustion than the control group of mice, in a dose-dependent manner. the maximal effect was observed at a dose of 10 mg/kg while more than 15 mg/kg had no effect. the increase of endurance was observed only when cap ... | 1997 | 9362118 |
| antibacterial activity of selected fatty acids and essential oils against six meat spoilage organisms. | the antibacterial activity of selected fatty acids and essential oils was examined against two gram-negative (pseudomonas fluorescens and serratia liquefaciens) and four gram-positive (brochothrix thermosphacta, carnobacterium piscicola, lactobacillus curvatus, and lactobacillus sake) bacteria involved in meat spoilage. various amounts of each preservative were added to brain heart infusion or mrs (deman, rogosa and sharpe) agars, and the minimum inhibitory concentration was determined for each ... | 1997 | 9310850 |
| resistance to tobamoviruses in transgenic tobacco plants expressing the coat protein gene of pepper mild mottle virus (korean isolate). | red pepper, one of the most important vegetable crops in korea, is severely affected by viral diseases causing 20-50% reduction in product yield. a pepper strain of tobacco mosaic virus (tmv-p) is the most common virus in red pepper. to study the molecular structure of the tmv-p virus, we generated cdna clones of the viral genome. partial sequencing of a few cdna clones revealed that tmv-p shares a 98% identity at the nucleotide level with the spanish isolate of pepper mild mottle virus (pmmv-s) ... | 1997 | 9264016 |
| intranasal capsaicin is efficacious in non-allergic, non-infectious perennial rhinitis. a placebo-controlled study. | several authors described capsaicin, the pungent substance in red pepper, as an efficacious therapy for non-allergic non-infectious perennial rhinitis (naniper). repeated capsaicin application induces peptide depletion and specific degeneration of the unmyelinated sensory c-fibres in the nasal mucosa. | 1997 | 9249272 |
| [structural changes in the tissues of white rats after capsaicin administration]. | tissue structure of albino rat lung, skin and cornea changing after administration of capsaicin (neurotoxin isolated from red pepper) was studied using light and electron microscope. 5 mg/kg dose causes tissue swelling and microcirculatory bed reaction. 200 mg/kg dose leads to more significant dystrophic tissue alterations. fibrosclerosis signs were found in certain cases. microcirculatory disorders are proposed as the main reason for tissue structure alterations observed, although the mechanism ... | 1997 | 9244551 |
| peppers and pain. the promise of capsaicin. | capsaicin, the most pungent ingredient in red peppers, has been used for centuries to remedy pain. recently, its role has come under reinvestigation due to evidence that the drug acts selectively on a subpopulation of primary sensory neurons with a nociceptive function. these neurons, besides generating pain sensations, participate through an antidromic activation in the process known as neurogenic inflammation. the first exposure to capsaicin intensely activates these neurons in both senses (or ... | 1997 | 9179523 |
| screening of aflatoxins in shiro and ground red pepper in addis ababa. | aflatoxin contamination of shiro and ground red pepper samples collected from government owned good stores, retail shops and open markets in. addis ababa was investigated. from sixty samples each of ground red pepper and shiro, 8 (13.33%) and 5 (8.33%) were positive for aflatoxins, respectively. only aflatoxin b1 was detected in both types of foodstuff. there was no significant difference between the proportion of aflatoxin contained in both ground red pepper and shiro samples. aflatoxin levels ... | 1996 | 9164040 |
| dietary red pepper ingestion increases carbohydrate oxidation at rest and during exercise in runners. | the effects of dietary hot red pepper on energy metabolism at rest and during exercise were examined in long distance male runners 18-23 yr of age. a standardized meal was given on the evening prior to the experiment. the subjects had a meal (2720 kj) with or without 10 g of hot red pepper for breakfast. during rest (2.5 h after meal) and exercise (pedaling for 1 h at 150 w, about 60% vo2max, using cycling ergometry), expired gasses and venous blood were collected. the meal with hot red pepper s ... | 1997 | 9139174 |
| effects of capsaicin on chemically-induced two-stage mouse skin carcinogenesis. | capsaicin (trans-8-methyl-n-vanillyl-6-nonenamide) is a principal pungent ingredient of hot red peppers. there are some controversies with regard to its inherent tumorigenicity and mutagenicity. the present work was undertaken to assess tumor initiating and promotional effects of capsaicin in a two-stage mouse skin carcinogenesis model. a single topical application of capsaicin (10 micromol) followed by twice-weekly applications of 12-o-tetradecanoylphorbol-13-acetate onto shaven backs of female ... | 1997 | 9103286 |
| presence of an acidic glycoprotein in the serum of arthritic rats: modulation by capsaicin and curcumin. | levels of various serum proteins were found to change in adjuvant induced arthritis. increased levels of a glycoprotein with an apparent molecular weight of 72 kda (gp a72) were observed in the sera of arthritic rats. gp a72 is an acidic glycoprotein with a pi of 5.1. gp a72 also showed antitryptic activity. the appearance of gp a72 in the serum preceded the onset of paw inflammation in arthritic rats and persisted in the chronic phase. oral administration of the antiinflammatory spice principle ... | 1997 | 9089639 |
| effect of capsianoside, a diterpene glycoside, on tight-junctional permeability. | previous work (hashimoto et al., (1994) biosci. biotech. biochem. 58, 1345) revealed that a sweet pepper extract enhanced the tight-junctional (tj) permeability of a human intestinal caco-2 cell monolayer. in the present study, the substance which modulated the tj permeability was chromatographically purified from the extract. the active substances were identified as capsianosides a-f, diterpene glycosides. treatment of the cells with capsianoside f, the most active compound, decreased the cellu ... | 1997 | 9042350 |
| isocratic non-aqueous reversed-phase high-performance liquid chromatographic separation of capsanthin and capsorubin in red peppers (capsicum annuum l.), paprika and oleoresin. | a simple, rapid high-performance liquid chromatography method has been devised in order to separate and quantify the xanthophylls capsorubin and capasanthin present in red pepper (capsicum annuum l.) fruits and preparations made from them (paprika and oleoresin). a reversed-phase isocratic non-aqueous system allows the separation of xanthophylls within a few minutes, with detection at 450 nm, using methyl red as internal standard to locate the various carotenoids and xanthophylls found in plant ... | 1997 | 9025261 |
| red pepper effect. | 1996 | 8995873 | |
| evidence for two types of phosphate translocators in sweet-pepper (capsicum annum l.) fruit chromoplasts. | we have investigated whether there is evidence for the presence of different types of phosphate translocators in envelopes purified from pepper-fruit chromoplasts. a method was developed that allowed the purification of envelope membranes from isolated pepper-fruit chromoplasts. proteoliposomes containing envelope-membrane proteins are able to import inorganic phosphate (p1) or glucose 6-phosphate (glc6p). in both cases, the rate of import is strongly dependent upon preloading of proteoliposomes ... | 1996 | 8947460 |
| effects of red-pepper diet on the energy metabolism in men. | we investigated the effects of dietary red pepper on the energy metabolism in male subjects. in the first experiment, after having a standardized dinner on the previous evening, the subjects consumed a breakfast (650 kcal) either with or without 10 g of red pepper. for 150 min after the meal, they took a rest and their expired gas was collected. during the initial 30 min after the meal, the energy expenditure tended to be higher in the red-pepper diet period than in the control diet period. for ... | 1995 | 8926537 |
| natural occurrence of mycotoxins in different spices in egypt. | a total of 120 different samples belonging to 24 kinds of species collected from different places at assiut governorate (egypt) were examined for the natural occurrence of mycotoxins. tlc analysis of spice extracts revealed the presence of aflatoxins (8-35 micrograms/kg) in 16 samples of anise, black pepper, caraway, black cumin, fennel, peppermint, coriander and marjoram, sterigmatocystin (10-23 micrograms/kg) in ten samples of red pepper, caraway, cumin and marjoram and citrinin (8-12 microgra ... | 1995 | 8919936 |
| capsaicin in diet does not affect glycogen contents in the liver and skeletal muscle of rats before and after exercise. | effects of capsaicin, a pungent principle of hot red pepper, on glycogen contents in the liver and skeletal muscle at rest and during exercise were studied in rats. the contents of glycogen in the liver and soleus muscle, and the concentrations of serum glucose, lactate, free fatty acid and glycerol were examined. capsaicin was supplemented at 0.014% of the experimental diet. each group of rats was fed the capsaicin-diet ad libitum for 7 days, and then both groups of rats were fed isoenergetic d ... | 1996 | 8866261 |
| red pepper-induced dermatitis in breast-fed infants. | we report a transient, erythematous dermatitis that formed in 2 infants shortly after breast-feeding from their mothers who had ingested food flavored with red pepper, although the mothers did not display any signs of dermatitis. | 1996 | 8864625 |
| [allergy associated with pepper and latex: new cross reaction?]. | the aim of this study was to point out the frequency of associated sensitization to rubber latex and to sweet pepper. the study included three populations of patients: patients allergic to rubber latex, patients sensitized to rubber latex and patients without any clinical symptoms for rubber latex and sweet pepper (negative controls). we pointed out a high frequency of patients sensitized to sweet pepper among the patients allergic or sensitized to rubber latex which lead to the hypothesis of a ... | 1995 | 8851036 |
| capsaicin or feeding with red peppers during gestation changes the thermonociceptive response of rat offspring. | capsaicin is responsible for the pungent sensation produced by red peppers on the body's mucous membranes. this substance is found naturally in the gender capsicum, widely used in the diet of different cultures in america, asia, and africa. in this paper we used the hot plate model (53 +/- 0.5 degrees c) to study the effect of acute thermonociceptive stimulus on escape response latency in the offspring of rats that were treated during gestation, either with an aqueous red pepper solution (capsic ... | 1996 | 8840903 |
| [daily intake of carotenoids (carotenes and xanthophylls) from total diet and the carotenoid content of selected vegetables and fuit]. | the recommended daily intake is currently either 2 mg of beta-carotene (recommended by dge, germany, in addition to 1.0 (0.8) mg retinol-equivalents for vitamin a requirement) or 5-6 mg of beta-carotene (recommended by nci, usa). the present studies were carried out to investigate to what extent a balanced diet prepared using household or cafeteria methods contributes to achieve the desired intake. beta-carotene and other carotenoids in the total daily diet samples were determined by rp-hplc. in ... | 1996 | 8815648 |
| influence of sundrying on the chemical composition, aflatoxin content and fungal counts of two pepper varieties--capsicum annum and capsicum frutescens. | samples of sundried, matured red pepper, capsicum annum with a moisture content (mc) of 12.7-26.8 percent had on dry weight basis, vitamin c, 5.0-6.4 mg/100 g; crude protein, 0.8-1.2 percent; total soluble solids, 3.3-4.1 percent, and fungal counts of log 4.4-4.5/g. ordinary matured red c. annum had mc, 75.7-78.2 percent vitamin c, 36.1-38.5 mg/100 g; crude protein, 2.4-2.8 percent; total soluble solids, 9.3-9.9 percent and fungal count of log 3.32-3.39/g. sundried matured red c. frutescens had ... | 1996 | 8811723 |
| inhibition of contractile tension by capsaicin in isolated rat papillary muscle. | 1. we examined effects of capsaicin (10(-9) - 10(-5) m), a pungent agent extracted from red pepper, on the contractile tension of rat ventricular papillary muscles stimulated at various cycle lengths (0.2, 0.5, 1, 2 and 5 sec). 2. capsaicin produced a marked concentration-dependent decrease in the amplitude, the rate of rise (dp/dt) and the rate of relaxation (dr/dt) of the tension. 3. however, the half relaxation time and the time to peak tension of the tension were slightly affected by the age ... | 1996 | 8742509 |
| capsaicin does not inhibit the intracellular calcium handling process in rat ventricular papillary muscle. | 1. we studied the effects of capsaicin, a pungent agent extracted from red pepper, on rested-state contraction (rsc) of isolated rat ventricular papillary muscles. 2. the rsc was induced by stimulation, after a rest interval of 5 sec to 10 min, after the twitch tension of the muscle preparation stimulated at the regular stimulus frequency of cycle lengths of 5, 1 or 0.2 sec attained the steady state. 3. drug effects were evaluated on the rsc in the presence of capsaicin 10(-5) m, caffeine 10(-2) ... | 1996 | 8742504 |
| major fruit and vegetable contributors to the main serum carotenoids in the spanish diet. | to identify the main sources of serum carotenoids (lutein, zeaxanthin, lycopene, beta-cryptoxanthin, alpha-carotene and beta-carotene) among the fruits and vegetables in the spanish diet, to be used in the design of food questionnaires and to provide useful information for epidemiological and comparative studies. | 1996 | 8730612 |
| capsaicin in hot chili pepper: carcinogen, co-carcinogen or anticarcinogen? | capsaicin (trans-8-methyl-n-vanillyl-6-nonenamide) is a major pungent ingredient of the capsicum fruits such as hot green and red peppers. besides its use as a food additive in various spicy cuisines, capsaicin is currently utilized for therapeutic purposes to treat various peripheral painful conditions such as rheumatoid arthritis and diabetic neuropathy. considering consumption of capsaicin as a food additive and its current medicinal application in humans, correct evaluation and precise asses ... | 1996 | 8621114 |
| problems with estimating vitamin c intakes. | the vitamin c content of foods was examined from two national databases and new values were obtained by hplc. hplc values were lower in four of the five highest vitamin c contributors to the us diet (orange juice, grapefruit, tomatoes and tomato juice, and potatoes), as well as in broccoli, red peppers, and cooked collard and mustard greens, compared with values from the other databases. when hplc values were substituted in the health habits and history questionnaire, the resulting estimates of ... | 1993 | 8460610 |
| aflatoxin contamination in foods and foodstuffs in tokyo: 1986-1990. | aflatoxins were determined in 3054 samples of foods or foodstuffs, including cereals, nuts, beans, spices, dairy products, dry fruits, and edible oil. samples were collected in tokyo from 1986 to 1990. aflatoxins were found in rice products, adlay, corn, crude sugar, peanut products, pistachio nuts, brazil nuts, sesame products, butter beans, white pepper, red pepper, paprika, nutmeg, and mixed spices. the highest incidence of aflatoxin contamination was observed in nutmeg (80%), and the highest ... | 0 | 8448440 |
| occurrence of the chromoplast protein chra correlates with a fruit-color gene in capsicum annuum. | plant geneticists have determined that the color of ripe fruits of sweet peppers (capsicum annuum l.) is determined by four genes: y, c1, c2 and cl. we have compared the electrophoretic behavior of chromoplast membrane proteins of seven varieties of c. annuum which differ in these genes. chra was detected only in the varieties that had a y+ genotype, and was not affected by variations in the other three genes. the identity of chra was verified by probing blots of sds gels with antiserum to chra. ... | 1993 | 8443347 |
| a rapid capsaicin-activated current in rat trigeminal ganglion neurons. | a subpopulation of pain fibers are activated by capsaicin, the ingredient in red peppers that produces a burning sensation when eaten or placed on skin. previous studies on dorsal root ganglion neurons indicated that capsaicin activates sensory nerves via a single slowly activating and inactivating inward current. in rat trigeminal neurons, we identified a second capsaicin-activated inward current. this current can be distinguished from the slow one in that it rapidly activates and inactivates, ... | 1994 | 8290592 |
| significance for humans of the nutrient contents of the dry fruit of tetrapleura tetraptera. | the nutritional quality of the dry fruit of tetrapleura tetraptera, a tropical deciduous forest tree with characteristic fruits, used as a spice, was assessed. the fruit shell, fruit pulp and seed contained varying amounts of nutrients such as protein, lipids and minerals, which were comparable and some were even higher than popular spices such as red pepper, onion, curry and ginger. the crude fibre content of the fruit shell was noteworthy and can be considered a good source of this nutritional ... | 1994 | 8146103 |
| induction of the anti-carcinogenic enzyme quinone reductase by food extracts using murine hepatoma cells. | over 145 extracts of vegetables, fruits, herbs, spices and beverages which are consumed regularly in the european diet have been surveyed for potential anti-carcinogenic activity using an assay which measures the induction of nad(p)h: (quinone acceptor) menadione oxidoreductase (quinone reductase, qr) activity in murine cells challenged with solutions of potential inducers. when appropriate the study has included extracts prepared from cooked and autolysed material. the results indicate that ext ... | 1994 | 8061594 |
| fermentation and sensory characteristics of kimchi containing potassium chloride as a partial replacement for sodium chloride. | a study was designed to determine the effects of substituting up to 50% of the nacl in kimchi, a fermented chinese cabbage (brassica pekinensis) product containing scallions, garlic, ginger and hot red pepper powder, with kcl. brine water (15% salt) used to soak cabbage contained nacl:kcl ratios of 1:0 (control), 5:1, 2:1 and 1:1 (wt:wt). total acidity and ph of kimchi reached acceptable ranges of 0.4-0.6% (as lactic acid) and 4.4-4.7, respectively, after 13 days of incubation at 13 +/- 1 degree ... | 1994 | 8043352 |
| role of capsaicin, curcumin and dietary n-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages. | reactive oxygen species (ros) generated by activated macrophages play an important role in the initiation of inflammation. ten different spice principles, some of which with known anti-inflammatory properties, were tested for their effect on generation of superoxide anions, hydrogen peroxide and nitrite radical generation by activated rat peritoneal macrophages. preincubation of macrophages with 10 microm capsaicin (from red pepper) or 10 microm curcumin (from turmeric) completely inhibited the ... | 1994 | 7981240 |
| [the value of polish field grown sweet pepper cultivars for freezing and pickling]. | raw and blanched sweet pepper and frozen goods and pickles produced of blanched and non-blanched vegetable were evaluated after 6-month storage, the following cultivars of polish origin being used in the screening: bryza, ino, jantar, kano, kujawianka, passat, sono, and zefir. the compared cultivars differed by the level of analysed indices. the variability range of dry matter content was 25%, of sugars 23%, of starch 97%, of protein 25%, of mineral constituents 24%, and of vitamin c 40%. the bl ... | 1994 | 7792520 |
| identification of a plastid protein involved in vesicle fusion and/or membrane protein translocation. | structural evidence has accumulated suggesting that fusion and/or translocation factors are involved in plastid membrane biogenesis. to test this hypothesis, we have developed an in vitro system in which the extent of fusion and/or translocation is monitored by the conversion of the xanthophyll epoxide (antheraxanthin) into the red ketocarotenoid (capsanthin). only chromoplast membrane vesicles from red pepper fruits (capsicum annuum) contain the required enzyme. vesicles prepared from the mutan ... | 1995 | 7777561 |
| detection of bixin, lycopene, canthaxanthin, and beta-apo-8'-carotenal in products derived from red pepper. | an analytical method using either thin layer or liquid chromatography is proposed for the detection of 4 pigments (bixin, lycopene, canthaxanthin and beta-apo-8'-carotenal) that can be used fraudulently to intensify the natural color of products derived from red pepper (oleoresins, paprika, paprika paste, etc.). similarly, the addition of other colorant natural products containing some of these pigments as major pigments (such as tomato for lycopene and bixa orellana seeds for bixin) can be dete ... | 2015 | 7756865 |
| capsaicin, a double-edged sword: toxicity, metabolism, and chemopreventive potential. | capsaicin (8-methyl-n-vanillyl-6-nonenamide) is a primary pungent and irritating principle present in chilies and red peppers which are widely used as spices. because of its selective effects on the functions of a defined subpopulation of sensory neurons, capsaicin is currently used as a versatile tool for the study of pain mechanisms and also for pharmacotherapy to treat several pain disorders. considering the frequent consumption of capsaicin as a food additive and its current medicinal use, c ... | 1995 | 7746093 |
| clastogenicity of red pepper (capsicum frutescens l.) extracts. | extracts from the fruits of capsicum frutescens l. were tested for their clastogenicity using the mouse-bone-marrow micronucleus (mouse-mn) assay. results of the mouse-mn, an in vivo method, indicated that the isolate cf-1 is clastogenic at the maximum tolerated dose of 1.22 mg/kg mouse. statistical analysis using the wilcoxon two-sample test showed that the null hypothesis, mu tetracycline = mucf-1, is acceptable at 0.05 and 0.01 degrees of significance. hence, the clastogenicity of cf-1 is sta ... | 1994 | 7510827 |
| hypocholesterolemic effect of red pepper & capsaicin. | 1980 | 7461749 | |
| [biological applications of raman resonance spectroscopy and micro-raman resonance spectroscopy]. | advantages are given to illustrate the possibilities of resonance raman spectroscopy in the studies of biological systems. a relation giving the size of porphinato-core of metalloporphyrins from resonance raman frequency is proposed. it can be applied to heme, even in lived state. by illuminating the sample through a microscope, resonance raman effect can be collected from 1 (micrometer)2 of sample. spectra of a vegetal-cell wall (pimento) and of a red corpuscle (hemoglobin) are shown as example ... | 2006 | 7332762 |
| high pressure liquid chromatographic determination of aflatoxins in spices. | high pressure liquid chromatography with fluorescence detection is used to determine aflatoxin in 5 common spices. a 10 micrometer microparticulate silica gel column is used with a dichloromethane-cyclohexane-acetonitrile solvent system to resolve aflatoxins b1, g1, b2, and g2. the fluorescence detector contained a silica gel-packed flowcell. samples of black, white, and red pepper, ginger, and nutmeg were extracted according to a previously published method. recoveries from aflatoxin-free sampl ... | 1981 | 7309657 |
| the effects of capsaicin on intestinal sodium and fluid transport. | capsaicin, the pungent component of red pepper, was studied to determine its inhibitory effect on fluid and na+ absorption using rat and hamster everted jejunal sacs. at a mucosal concentration of 140 mg% incubated for 60 min, capsaicin reduced the fluid transport into the serosal side by 14.8% in rat and 23.9% in hamster. similarly, na+ transport was also inhibited by 12.5% and 26.2% in rat and hamster, respectively. such decrease in serosal sodium coincided with the increase in na+ content of ... | 1980 | 7277177 |
| [effects of inflammation and stimulant diets on functions of autonomic nervous system (author's transl)]. | in usual medical consultation, we have been met a lot of female patients suffering from disturbances of autonomic nervous system such as headache, shoulder-ache and so on. experiments were designed to elucidate whether or not these disturbances of autonomic nervous system were induced by inflammation and accelerated by stimulant diets. functions of autonomic nervous system were examined by lipolysis in rat epididymal adipose tissue which was partly controlled by sympathetic nervous system. it wa ... | 1981 | 7246063 |
| application of a minicolumn detection method for screening spices for aflatoxin. | the minicolumn of holaday and lansden was modified by increasing the height of neutral alumina and including a layer of anhydrous sodium sulphate. using this procedure, aflatoxin was detected in 18 of 125 samples of black pepper, red pepper, ginger and turmeric. a few samples of each spice contained aflatoxin, although red pepper and turmeric showed the highest incidence. aflatoxin b1 quantities ranged from 10 ug/kg to 120 ug/kg when estimated quantitatively by visual comparison with standards o ... | 1980 | 6769994 |
| capsaicin pretreatment prevents disruption of the blood-aqueous barrier in the rabbit eye. | capsaicin, the irritating agent of red pepper, produces ocular inflammation through a neurogenic mechanism. the present study is concerned with the long-term effects of capsaicin pretreatment on the capacity of the eye to respond to different inflammatory stimuli. following retrobulbar injection of capsaicin to rabbits the aqueous flare response induced by subsequent infrared irradiation (ir) of the iris, subcutaneously administered alpha-melanocyte-stimulating hormone (alpha-msh) and exogenousl ... | 1983 | 6602116 |
| [contact allergy to anacardiaceae. a review and case reports of poison ivy allergy in central europe]. | in europe, as opposed to north america, poison-ivy rash is hardly known. for this reason a detailed review of the allergenic members of the anacardiaceae family is given, and the misleading nomenclature of "poison ivy", "poison oak", and some other species of this family are discussed. an up-to-date representation of the chemical structure of the allergenic substance group (denoted as "urushiol") from this family is provided as well as botanical information regarding the plants themselves. preve ... | 1983 | 6227468 |
| microflora of black and red pepper. | dilution cultures of 30 samples of ground black pepper yielded an average of 39,000 colonies of fungi per g, with a range of 1,700 to 310,000 per g. total numbers of colonies of bacteria from 11 samples averaged 194,000,000 per g, with a range from 8,300,000 to 704,000,000 per g. a variety of fungi grew from nearly all surface-disinfected whole peppercorns that were cultured. thirteen samples of ground red pepper from the united states yielded an average of 1,600 colonies of storage fungi per g ... | 1967 | 6035055 |
| irreversible impairment of thermoregulation induced by capsaicin and similar pungent substances in rats and guinea-pigs. | 1. in rats and guinea-pigs a subcutaneous or intraperitoneal injection of capsaicin, the substance responsible for the pungency of red pepper, produces profound hypothermia associated with skin vasodilatation.2. after large doses of capsaicin rats and guinea-pigs become insensitive to the hypothermic action of capsaicin. this densensitization is apparently irreversible since it is present months after the capsaicin treatment.3. capsaicin-desensitized animals are no longer able to protect themsel ... | 1970 | 5498502 |
| [fermentation of the pimento used for stuffing green olives]. | 2000 | 5083210 | |
| processing of pimento waste to provide a pigment source for poultry feed. | 1974 | 4858833 | |
| the effect of red pepper (capsicum frutescens) on gastric acid secretion. | 1973 | 4777542 | |
| control of green peach aphid on sweet peppers in delaware. | 1972 | 4628649 | |
| [antibacterial properties of some spice plants before and after heat treatment]. | this study was carried out to understand the antibacterial properties of some spice plants before and after heat treatment in boiling water. the samples included the core and the outer layers of onion, the white and the green parts of green onion, garlic bulb, ginger, ginger root, sweet pepper, chili pepper, brown pepper, and mustard. the test microorganisms included escherichia coli, salmonella typhimurium, vibrio parahaemolyticus, pseudomonas aeruginosa, proteus vulgaris, staphylococcus aureus ... | 1985 | 4064797 |
| [toxicoderma caused by sweet red pepper]. | 1985 | 4036294 | |
| [the differentiation of parts of paprika fruit by analysis of their mineral constituents]. | in order to determine the trace metals and minor elements in the different parts of the paprika fruit (red pepper) samples were ashed and analysed by an emission spectrographic method. analysis lines of 9 elements (b, p, fe, mg, si, mn, al, ca, cu) were measured in the arc spectra of the samples, and the logarithmic intensity data processed by pattern recognition methods. from the data obtained the three components of the plant ("exocarp", "seed", and "stem") could be correctly classified. mixtu ... | 1985 | 4002864 |
| capsaicin pretreatment attenuates suppression of food intake by cholecystokinin. | capsaicin, the pungent principal in red pepper, has been shown to damage small-diameter peptide-containing sensory neurons. suppression of feeding by cholecystokinin octapeptide (cck op) was attenuated after systemic pretreatment with capsaicin. capsaicin pretreatment did not attenuate suppression of food intake by intragastric preloads. pretreatment of rats with microgram quantities of capsaicin injected into the fourth ventricle, near the sites of vagal afferent termination, also attenuated cc ... | 1985 | 3985191 |
| effect of spiced food on metabolic rate. | since the time of lavoisier it has been known that the ingestion of food in animals and man produces an increase in oxygen consumption. this increase in metabolic rate was originally called 'specific dynamic action' (sda) and is now widely referred to as the thermic effect (te) of food or diet-induced thermogenesis (dit) (rothwell & stock, 1981). much of the early work on the thermic effect was confined to the type and amount of food, notably the macronutrients--proteins, fats and carbohydrates. ... | 1986 | 3957721 |
| co-carcinogenic effects of several korean foods on gastric cancer induced by n-methyl-n'-nitro-n-nitrosoguanidine in rats. | in study i, 48 aci and fisher inbred rats were given mnng 100 micrograms/ml, with or without 1 per cent or 3 per cent red pepper diet; in study ii, 164 sprague-dawley rats given mnng 100 micrograms/ml, with or without 5 per cent or 10 per cent nacl; in study iii, 181 wistar rats given mnng 83 micrograms/ml with or without maejoo 10 gm per cent/diet; in study iv, 78 wistar rats given mnng 83 micrograms/ml with or without ginseng extract 150 micrograms/ml; in study v, 120 wistar rats given mnng 83 ... | 1985 | 3831496 |
| capsaicin, a pungent principle of hot red pepper, evokes catecholamine secretion from the adrenal medulla of anesthetized rats. | using a direct monitoring system for catecholamine (ca) secretion into the adrenal vein, we have demonstrated that capsaicin (cap) evokes ca secretion from the adrenal medulla of pentobarbital-anesthetized rats. a significant increase in epinephrine (e) secretion was seen in rats infused with cap (200 micrograms/kg, i.v.) without a detectable lag after the infusion. norepinephrine (ne) secretion evoked by cap was fairly weak compared with e secretion. the secretion of e evoked by cap was dose-am ... | 1987 | 3814133 |
| [organic acids of various kinds of vegetables. iv. changes in the acids and sugar in tomatoes, sweet peppers and cucumbers during development and ripening]. | concentrations of organic acids and sugars in tomatoes and sweet peppers change notably during ripening. the concentration of malic acid decreases while that of citric acid increases considerably and in redripe fruits clearly exceeds the content of malic acid. several maxima and minima in acid concentrations occur during development. both species show constant proportions of citric and isocitric acid (200:1 and 30:1 respectively). in sweet pepper, quinic and ascorbic acid can be found in noticea ... | 2013 | 3811599 |
| simplified cleanup and gas chromatographic determination of organophosphorus pesticides in crops. | a simple and efficient cleanup method for gas chromatographic determination of 23 organophosphorus pesticides in crops including onion is described. the sample was extracted with acetone. the extract was purified with coagulating solution, which contained ammonium chloride and phosphoric acid, and then filtered by suction. the filtrate was diluted with nacl solution and reextracted with benzene. the organic layer was evaporated and injected into a gas chromatograph equipped with a flame photomet ... | 1987 | 3610958 |
| some pungent principles of spices cause the adrenal medulla to secrete catecholamine in anesthetized rats. | we recently reported that capsaicin, a pungent principle of hot red pepper, evokes catecholamine secretion from the rat adrenal medulla. in this study, the effects of some pungent principles of spices on adrenal catecholamine secretion were investigated as compared with that of capsaicin. an increase in catecholamine, especially epinephrine, secretion was observed not only on capsaicin infusion but also on piperine (a pungent principle of pepper) and zingerone (ginger) infusion. even on infusion ... | 1988 | 3375268 |
| mould deterioration of agricultural commodities during transit: problems faced by developing countries. | huge quantities of agricultural commodities are being either imported or exported by the developing countries. the commodities have to be transported from the fields of cultivation to the centres of consumption, considerable time being taken for the movement not only because of long distances but also because of various socio-economic, environmental and biological reasons. these commodities are likely to be damaged by mould growth and subsequent aflatoxin accumulation. if the contamination occur ... | 2010 | 3275325 |
| study of the bacillus flora of nigerian spices. | bacteriological examination of 230 samples of five different unprocessed spices (aligator pepper, red pepper, black pepper, thyme and curry powder) collected randomly from port harcourt main markets revealed that the spices were highly contaminated, with bacterial counts ranging from 1.8 x 10(4) to 1.1 x 10(8) per gram. bacillus cereus was isolated in high numbers in the majority of the 230 samples examined. it was also observed that other bacillus spp. including b. subtilis, b. polymyxa and b. ... | 1988 | 3275301 |
| non-mutagenicity of capsaicin in albino mice. | capsaicin, the active principle of red pepper, administered intraperitoneally to adult male mice at doses of 0.4, 0.8 or 1.6 mg/kg body weight/day (1/20, 1/10 or 1/5 of the ld50) on five consecutive days, did not induce any clinical signs of toxicity. no significant alterations were observed in epididymal weights, caudal sperm counts, testicular weights or testicular histology. in the sperm morphology assay, sperms at 1, 3, 5 and 7 wk did not reveal any treatment-related increase in the incidenc ... | 2011 | 3209135 |
| headaches and sinus disease: the endoscopic approach. | headaches can be of sinugenic origin even if this cause may not be suspected from the case history. endoscopy of the lateral nasal wall with rigid cold light endoscopes in combination with polytomography or computed tomography usually will reveal the underlying causes hidden from the unaided eye, the operating microscope, and standard x-ray examination. small lesions in the lesser cells of the ethmoid complex may give rise to headaches, especially when located in the key areas of the ethmoid inf ... | 1988 | 3140703 |
| inhibition of calcium and calmodulin-dependent phosphodiesterase activity in rats by capsaicin. | capsaicin, reported to elevate hormone sensitive lipase (hsl), is also found to inhibit the ca++ and calmodulin-dependent camp phosphodiesterase (pde) activity in adipose tissue of rats, fed high fat diet. the dependence of the enzyme activity on ca++ and calmodulin in vitro, in control rats, is shown by its substantial lowering in the presence of egta and inhibition by trifluoperazine (tfp) (ic50 between 10-20 microm). this enzyme activity is also inhibited by both red pepper extract (80% inhib ... | 1987 | 3118870 |
| effect of red pepper and black pepper on the stomach. | spices have long been implicated as a cause of gastric mucosal injury. we assessed the effects of red and black pepper on the gastric mucosa using double-blind intragastric administration of test meals containing red pepper (0.1-1.5 g) or black pepper (1.5 g) to healthy human volunteers; aspirin (655 mg) and distilled water were used as positive and negative controls, respectively. serial gastric washes were performed after test meal administration and gastric contents were analyzed for dna, pep ... | 1987 | 3103424 |
| spectrophotometric analysis of irradiated spices. | seven different spices (thyme, cinnamon, coriander, caraway, pimento, paprika, black pepper) were treated by gamma radiation at an absorbed dose of 10 kgy, and the effect on chemical quality was determined. the effects of this dose were assessed by spectrophotometric analysis of some water-soluble constituents of spices (carbohydrates; carbonyl compounds) and on the content of water-insoluble steam-volatile oils. the colour of paprika and the content of piperine in pepper held in different packa ... | 1987 | 3040629 |
| effects of capsaicin on lipid metabolism in rats fed a high fat diet. | effects of capsaicin, a pungent principle of hot red pepper, were studied in experiments using male rats fed a diet containing 30% lard. capsaicin was supplemented at 0.014% of the diet. the level of serum triglyceride was lower when capsaicin was present in the diet than when it was not. levels of serum cholesterol and pre-beta-lipoprotein were not affected by the supplementation of capsaicin. the perirenal adipose tissue weight was lower when capsaicin was present in the diet than when it was ... | 1986 | 2875141 |
| resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper. | resiniferatoxin is an extremely irritant diterpene present in the latex of several members of the genus euphorbia. its mechanism of action has been shown to be clearly distinct from that of the structurally related phorbol esters. since resiniferatoxin possesses a 4-hydroxy-3-methoxyphenyl substituent, a key feature of capsaicin, the major pungent ingredient of plants of the genus capsicum, we examined the ability of resiniferatoxin to induce typical capsaicin responses. we report here that trea ... | 1989 | 2747924 |