Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| lipid and lipoprotein effects on endothelial eicosanoid formation. | an important function of endothelium is to release pgi2, a prostaglandin produced from arachidonic acid that prevents platelet aggregation and causes arterial relaxation. small amounts of other eicosanoids also are produced, but their role in endothelial function has not been elucidated. much of the arachidonic acid present in the endothelium is obtained preformed from the plasma, either as ffa or from lipoproteins. arachidonic acid is efficiently incorporated into endothelial lipids even when o ... | 2011 | 3061005 |
| a novel action of activin a: stimulation of insulin secretion in rat pancreatic islets. | the present study was conducted to examine an action of activin a on insulin secretion from rat pancreatic islets. in a batch incubation system, activin a stimulated insulin secretion in a dose-dependent manner at concentrations higher than 1 nm. furthermore, activin a greatly potentiated glucose-induced insulin release. when islets were perifused with 1 nm activin a, insulin secretion was barely affected in this system. however, the insulin response to 16.7 mm glucose was greatly enhanced. both ... | 1988 | 3052451 |
| free insulin profiles during intensive treatment with biosynthetic human insulin. | 24 h profiles of free insulin and glucose were determined in insulin-dependent diabetic patients on intensive insulin regimens with biosynthetic human insulin, either as continuous subcutaneous insulin infusion (csii) with mealtime bolus doses (n = 6), or intensified conventional insulin therapy (icit) with preprandial injections of regular insulin and intermediate-acting insulin at bedtime (n = 6). the free insulin profiles were similar to the normal profiles but there were some important diffe ... | 1988 | 3044863 |
| roles of hormonal and nutritional factors in the regulation of rat liver alcohol dehydrogenase activity and ethanol elimination rate in vivo. | fasting reduced the liver alcohol dehydrogenase (adh) activity by 51% (p less than 0.001). insulin, within 2 hr, increased the adh activity found in fasted animals by 28% (p less than 0.02). insulin administration failed to stimulate the reduced adh activity in diabetic rats. however, adh activity in the diabetic-fed rats decreased by 52-54% (p less than 0.001) compared to normal-fed rats regardless of whether they were meal-fed or refed the normal chow. glucagon blocked by 15% (p less than 0.02 ... | 1988 | 3044171 |
| t and b peripheral blood lymphocytes in normal and lymphocytotic sheep. | surface immunoglobulins (sig), peanut agglutinin (pna), spontaneous erythrocyte rosette (e-rosette) and helix pomatia (hp) marker were investigated in normal and bovine leukemia virus (blv)-infected sheep. in normal sheep, 19.3% +/- 4.9 of peripheral blood lymphocytes (pbl) were sig+, whereas 58% +/- 5.69 were pna+, and 19.6 +/- 5.2 were e-rosette forming cells (e-rfc). in blv-induced lymphocytotic sheep, sig+ cells in pbl reached 59.4% +/- 15.06. in the same animals, pna bound to 20.6% +/- 9.69 ... | 1987 | 3040327 |
| localization of quantitative changes in pulmonary beta-receptors in ovalbumin-sensitized guinea pigs. | impaired beta-receptor function has been postulated as one factor contributing to airway hyperreactivity in asthmatic patients. although numerous indirect studies have cast doubt on this theory, none of these previous investigations has been able to directly measure changes in beta-receptor number on intrapulmonary structures capable of affecting the physiologic changes seen in this disease state. to help clarify the intrapulmonary location of such changes, a model of allergic bronchoconstrictio ... | 1987 | 3037954 |
| regional variation in high-density lipoprotein binding to human adipocyte plasma membranes of massively obese subjects. | obesity is associated with significant changes in cholesterol and lipoprotein metabolism. high density lipoprotein (hdl) cholesterol is often reduced and adipose tissue cholesterol stores are increased in obese individuals. this prompted a study on the binding of hld fractions (hdl2 and hdl3) to adipocyte plasma membranes obtained from massively obese subjects (bmi greater than 37 kg m-2) undergoing gastroplasty. regional variation in hdl binding to these adipocyte plasma membranes was demonstra ... | 1987 | 3032643 |
| immunosuppressive properties of human placenta: study of supernatants from short-term syncytiotrophoblast cultures. | using collagenase and mechanical treatment to attempt to eliminate cellular contamination such as macrophages and decidual cells, trophoblast enriched cell suspensions were isolated from the human placenta. with a view to assessing the role of trophoblast in impairing maternal rejection of the fetus, supernatants (spl4) were prepared from these placental cells after short-term culture (4 h). the immunosuppressive activity of these supernatants was studied following application to mitogen-stimula ... | 1986 | 3023607 |
| formation of lattice-like inclusions in circulating erythroblasts of the laboratory mouse (hea/hea) with hereditary congenital erythroblastic anemia. | 1986 | 3020854 | |
| [electron microscopy and histochemical studies of the origin and function of myoepithelioid cells in glomangioma and peripheral barrier arteries]. | epithelioid cells (myoepithelioid cells, glomus cells) are a structural element characteristic of hoyer-grosser shunts (glomus organs, arterio-venous epithelioid cell glomerula) and bailey's glomangioma (masson's angio-neuromyome-artériel, glomus tumors). their functional importance cannot be estimated without knowledge of their histogenetic origin. the myoepithelioid cells are derived from smooth muscle cells, which can be shown ultrastructurally, histochemically, or by light microscopy. | 2010 | 3020817 |
| [nuclear magnetic resonance spectroscopy in medicine: biochemistry of intact tissues]. | 1986 | 3020443 | |
| [nuclear magnetic resonance spectroscopy in medicine: biochemistry of intact tissues]. | 1986 | 3020443 | |
| [morphological changes caused by adrenalectomy in rabbits]. | 1986 | 3019628 | |
| [morphological changes caused by adrenalectomy in rabbits]. | 1986 | 3019628 | |
| central nervous system lesions in suckling mice and rats inoculated intranasally with sialodacryoadenitis virus. | suckling cd-1 and cfw mice and wi wistar rats were inoculated intranasally with sialodacryoadenitis virus. in animals inoculated during the first week of life, there was an acute necrotizing encephalitis with malacia and minimal inflammatory cell response. in mice and rats which survived for up to 12 days post inoculation, loss of brain substance, gitter cells and occasionally mineralized debris were seen. viral antigen was readily demonstrated in neurons and nasal epithelium in trypsin-treated, ... | 1986 | 3004003 |
| demonstration of non-degraded aleutian disease virus (adv) proteins in lung tissue from experimentally infected mink kits. brief report. | isolates of adv replicate to rather high quantities in lungs from neonatally infected mink kits. the virus was analysed for polypeptide composition, and for the first time high molecular weight polypeptides have been observed in in vivo produced advs. these polypeptides are analogous to those of in vitro produced advs. the molecular weights of the structural polypeptides of the low virulence pullman adv and the highly virulent dk and utah i isolates of adv were found to be 88kd and 78kd and in v ... | 1986 | 3002299 |
| restriction endonuclease mapping and cloning of mycobacterium fortuitum var. fortuitum plasmid pal5000. | a restriction map of mycobacterium fortuitum var. fortuitum plasmid pal5000 was established. the unique sites for apai, bamhi, bglii, bsteii, clai, ecori, ecorv, hpai, kpni and nari were located on the 5.0-kb plasmid. the plasmid had no sites for ahaiii, bcli, hindiii, psti, sphi and xbai. pal5000 was cloned into pbr322 and propagated in escherichia coli. three hybrid pal5000-pbr322 plasmids carrying the complete pal5000 sequence were constructed by joining the plasmids at their bamhi, ecori or ... | 1985 | 3002238 |
| restriction endonuclease mapping and cloning of mycobacterium fortuitum var. fortuitum plasmid pal5000. | a restriction map of mycobacterium fortuitum var. fortuitum plasmid pal5000 was established. the unique sites for apai, bamhi, bglii, bsteii, clai, ecori, ecorv, hpai, kpni and nari were located on the 5.0-kb plasmid. the plasmid had no sites for ahaiii, bcli, hindiii, psti, sphi and xbai. pal5000 was cloned into pbr322 and propagated in escherichia coli. three hybrid pal5000-pbr322 plasmids carrying the complete pal5000 sequence were constructed by joining the plasmids at their bamhi, ecori or ... | 1985 | 3002238 |
| [surgery in the treatment of patients with small cell lung cancer]. | the data on surgical and combined treatment of 52 cases of small cell lung cancer are presented and the end results are evaluated. the findings on survival time make the case for surgery as a component of combined treatment of tumor. the best results were obtained in cases of stage i and ii tumor, absence of metastases into intrathoracic lymph nodes, tumor invasion limited to bronchopulmonary lymph nodes or the root of the lung, intermediate cell pattern of small cell lung cancer and surgery fol ... | 2010 | 2998088 |
| oestrus phases of the syrian hamster. | 1988 | 2976222 | |
| the effect of oral retinoid therapy on the normal human immune system. | twenty four patients were studied prior to and after 6 and 12 weeks therapy with isotretinoin (17 patients) for acne and related disorders, or with etretinate (7 patients) for psoriasis and related disorders. patients treated with isotretinoin had a significant reduction in natural killer cell activity at an effector: target cell ratio of 100: 1 at 12 weeks and also a reduction in natural killer cell numbers at this time. patients treated with etretinate had elevated natural killer cell activity ... | 1988 | 2972309 |
| activity of trospectomycin against bacteroides fragilis and other bacteroides species. | the in vitro activity of trospectomycin (u-63366; 6'-n-propyl spectinomycin pentahydrate sulfate) was evaluated against 189 clinical isolates of the bacteroides fragilis group and 65 bacteroides species isolates. at less than or equal to 8 micrograms/ml, the activity of trospectomycin compared favorably with those of clindamycin and cefoxitin against b. fragilis, bacteroides distasonis, and bacteroides vulgatus, and there was no cross resistance to these three drugs among the strains of the b. f ... | 1988 | 2967671 |
| hysteroscopic cannulation and lavage in the treatment of proximal tubal occlusion. | in two patients with apparent pto, as diagnosed by hsg and laparoscopy, tubal patency was restored by hysteroscopic cannulation of the tubal ostia, followed by direct lavage. tubal resection and reanastomosis/reimplantation may not be necessary for all patients with apparent pto. | 2010 | 2957240 |
| normal trunk muscle strength and endurance in women and the effect of exercises and electrical stimulation. part 2: comparative analysis of electrical stimulation and exercises to increase trunk muscle strength and endurance. | several studies have shown positive correlations between muscle strength, flexibility, and the frequency of low-back pain. weak trunk musculature and decreased endurance have thereby come to be identified as significant risk factors in the development of occupational back problems. because it is widely accepted that exercise plays an important role in the conservative treatment and prevention of low-back pain, the goals of most rehabilitative programs involves improving the strength and enduranc ... | 2010 | 2954215 |
| [relation between c-reactive protein and fever during treatment of acute infections in children]. | 2010 | 2950470 | |
| the effect of caffeine on fragile x expression. | caffeine has been reported to enhance the expression of the fragile x [fra(x)] and common fragile sites in peripheral blood lymphocyte cultures (pblc) treated with 5-fluorodeoxyuridine (fudr). one of the effects of caffeine on replicating cells is inhibition of dna repair suggesting that fragile sites may be regions of dna with a high rate of misreplication under the conditions of thymidylate stress induced by fudr. we have studied the effect of caffeine on the expression of the fra(x) and commo ... | 2010 | 2940164 |
| [education in nutrition. goals and methods]. | 2010 | 2937426 | |
| [adaptive effect and withdrawal syndrome of propranolol in relation to norepinephrine and epinephrine]. | 1985 | 2934953 | |
| an anthropometric assessment of huntington's disease patients and families. | an anthropometric investigation was designed to evaluate patterns of physical deterioration in huntington's disease (hd). in this study a comprehensive set of measurements was taken including height, weight, body circumferences, skinfold thickness, and craniofacial, linear, and breadth components of the body, on 44 normal, 26 affected, and 70 at-risk individuals between 14 and 88 years of age. the anthropometric data were converted to z-scores using standards to adjust for age and sex difference ... | 2010 | 2932916 |
| time-resolved fluorescence immunoassay system especially suited for research applications. | 2009 | 2920419 | |
| free and sulfoconjugated catecholamines in normotensive uremic patients: effects of hemodialysis. | in 9 normotensive uremic patients undergoing chronic hemodialysis, the baseline plasma catecholamines varied widely from low-normal to very high; sulfoconjugated plasma catecholamines were constantly high. a dialysis-induced fall of all sulfated catecholamines and epinephrine was observed. norepinephrine decreased in 5 patients and increased in 4, with a strong inverse correlation between predialysis norepinephrine and delta norepinephrine (p less than 0.0001). no correlation was evident between ... | 2010 | 2918946 |
| an american board of orthodontics case report. | a case report is presented of a class ii, division 1 malocclusion with severe excess overjet, vertical maxillary excess, maxillary skeletal protrusion, and relative mandibular retrognathia. the case was treated according to the standards of the american board of orthodontics. | 2010 | 2916472 |
| the halo skeletal fixator. principles of application and maintenance. | the halo skeletal fixator, originally developed for use in patients with poliomyelitis, is now widely used with many types of cervical spine instabilities. despite its demonstrated effectiveness, certain problem areas, including pin loosening and infection, have been identified. these problems have subsequently inspired detailed studies of skull osteology, biomechanics of pin fixation, and comparisons of techniques of application. based on these studies, specific recommendations concerning the a ... | 2010 | 2912611 |
| protective role of serum antibody in immunity to chlamydial genital infection. | female guinea pigs were injected intraperitoneally with pooled immunoglobulin derived from animals immunized to the chlamydial agent of guinea pig inclusion conjunctivitis. genital infections in animals receiving pooled immunoglobulin from immune animals were markedly decreased with regard to the number of inclusions detected compared with control animals. these data indicated that serum-derived antibody was able to provide a degree of protection against a chlamydial genital tract infection. | 1989 | 2909492 |
| long term results of treatment of budd-chiari syndrome by side to side portacaval shunt. | this is a report of a long term prospective study of 13 seriously ill patients with budd-chiari syndrome as a result of occlusion of the hepatic veins who were treated by side to side portacaval shunt from four to 78 weeks after the onset of symptoms and who were under observation for three to 16 years. the patient population was young, ranging in age from 19 to 45 years; seven were men and six were women. the presumed cause was the use of oral contraceptives in three, polycythemia rubra vera in ... | 2010 | 2909130 |
| future trends in the management of peptic ulcer disease. | future trends in the short- and long-term management of peptic ulcer disease are considered. the present state of development of pharmacologic agents for the short-term healing of duodenal and gastric ulcer is impressive, and high rates of healing with rapid symptom relief can be safely achieved with several agents. the problem of ulcer recurrence has not been solved, although new work concerning the role of campylobacter pylori holds promise. the mortality of acute gastrointestinal haemorrhage ... | 1988 | 2906462 |
| nonpalpable testes in young boys: evaluation with mr imaging. | a prospective evaluation of magnetic resonance (mr) imaging for localization of a nonpalpable testis was performed in 24 boys aged 11 months to 6 years. definitive surgical follow-up was obtained for 15 nonpalpable testes in 14 patients who form the basis of this study. mr imaging correctly indicated the unilateral absence of a testis in six of seven patients prospectively and all seven patients retrospectively. surgically localized undescended testes were identified with mr imaging in five of e ... | 2010 | 2902656 |
| use of reca protein to enrich for homologous genes in a genomic library. | reca protein-coated probe has been utilized to enrich genomic digests for desired genes in order to facilitate cloning from genomic libraries. using a previously cloned hla-b27 gene as the reca-coated enrichment probe, we obtained a mean 108x increase in the ratio of specific to nonspecific plaques in lambda libraries screened for b27 variant alleles of estimated 99% homology to the probe. class i genes of lesser homology were less enriched: 6.7x for non-b27 genes of estimated greater than 95% h ... | 2010 | 2901713 |
| possible association between breast cancer and malignant melanoma. | 2010 | 2898922 | |
| possible association between breast cancer and malignant melanoma. | 2010 | 2898922 | |
| intrathecal synthesis of antibodies to human t lymphotropic virus type i and the presence of igg oligoclonal bands in the cerebrospinal fluid of patients with endemic tropical spastic paraparesis. | tropical spastic paraparesis (tsp), a neuromyelopathy predominantly involving the pyramidal tract and commonly observed in tropical and equatorial areas, was recently found to be associated with human t lymphotropic virus type i (htlv-i). we investigated sera and cerebrospinal fluid (csf) from 19 patients with tsp who were from the caribbean area, french guiana, and africa. our results showed an elevated intra-blood-brain barrier igg synthesis rate and an elevated igg index, with an increased ht ... | 1988 | 2897399 |
| effect of infection with eimeria tenella upon the cecal bacterial population in monoflora chickens. | monoflora chickens were established at 2 days of age by an oral inoculation with one of six species of bacteria (lactobacillus acidophilus, bifidobacterium thermophilum, bacteroides vulgatus, clostridium perfringens, escherichia coli, or streptococcus faecalis) and were infected with eimeria tenella (5 x 10(4) oocysts per bird) 2 days later. there were two experimental groups for each bacterium: birds infected with bacteria alone and birds infected with a combination of bacteria and e. tenella. ... | 1987 | 2888103 |
| structure of bordetella pertussis peptidoglycan. | bordetella pertussis tohama phases i and iii were grown to the late-exponential phase in liquid medium containing [3h]diaminopimelic acid and treated by a hot (96 degrees c) sodium dodecyl sulfate extraction procedure. washed sodium dodecyl sulfate-insoluble residue from phases i and iii consisted of complexes containing protein (ca. 40%) and peptidoglycan (60%). subsequent treatment with proteinase k yielded purified peptidoglycan which contained n-acetylglucosamine, n-acetylmuramic acid, alani ... | 1987 | 2887547 |
| phorbol ester and phospholipase c-induced growth hormone secretion from pituitary somatotroph adenoma cells in culture: effects of somatostatin, bromocriptine, and pertussis toxin. | to clarify the role of the breakdown of phosphatidylinositol 4,5-bisphosphate (pip2) in gh secretion in human somatotrophs and the effects of inhibitors of gh secretion on this mechanism, we studied the effects of 12-tetradecanoylphorbol-13-acetate (tpa) and phospholipase c (plase c) on gh secretion and the interactions of somatostatin (srih), bromocriptine, and pertussis toxin (iap) with tpa or plase c, using human gh-secreting pituitary adenoma cells in culture. srih (10(-9)-10(-7) m) inhibite ... | 1987 | 2880863 |
| dose versus survival time curves in the evaluation of 'prompt' and 'delayed' acute toxicities. | the acute toxicity of arecoline, diisopropylfluorophosphate, nicotine and pilocarpine alone or in association with atropine has been evaluated from percentage lethality and from the linear correlation of (doses/(survival time] vs doses. the experimental points obtained with arecoline and diisopropylfluorophosphate, alone or in association with atropine 50 mg kg-1, are apparently ordered according to two straight lines. that at lower doses gave the ld50 values of the compounds studied. the values ... | 2010 | 2869128 |
| foot and ankle injuries in theatrical dancers. | the theatrical dancer is a unique combination of athlete and artist. the physical demands of dance class, rehearsal, and performance can lead to injury, particularly to the foot and ankle. ankle sprains are the most common acute injury. chronic injuries predominate and relate primarily to the repeated impact loading of the foot and ankle on the dance floor. contributing factors include anatomic variation, improper technique, and fatigue. early and aggressive conservative management is usually su ... | 2010 | 2866150 |
| post-translational processing of anglerfish islet somatostatin precursors. | two distinct somatostatin precursors are synthesized in anglerfish (af) islets. in addition to a precursor which has somatostatin 14 (ss-14) as a c-terminal cleavage product, a precursor which contains at its c-terminus [tyr7, gly10] ss-14 as a potential cleavage product is also synthesized. however, even though an arg-lys pair is located immediately n-terminal to ala1 of the c-terminal tetradecapeptide, [tyr7, gly10]ss-14 was not found in significant amounts in extracts of af islets. instead, a ... | 2010 | 2863927 |
| antiviral chemoprophylaxis for cytomegalovirus infection. | 1988 | 2849602 | |
| [role of alpha-1 and alpha-2-adrenoreceptors in achieving the compensatory response of the hemostasis system to plasmin]. | 1988 | 2849566 | |
| is ap4a involved in dna repair processes? | hepatoma tissue culture (htc) cells were incubated in the presence of the alkylating agent n-methyl-n'-nitro-n-nitrosoguanidine (mnng) to study the variations in the bisnucleosides polyphosphates (ap4x) pool size. a transient but sensitive accumulation of these compounds is observed; if 3-aminobenzamide (3ab) which is a potent inhibitor of the adp-ribosyltransferase (adprt) is added after the mnng treatment, a more pronounced and persistent accumulation of ap4x can be seen. a moderate heat-shock ... | 2010 | 2839348 |
| the red nucleus activity in rats deprived of the inferior olivary complex. | the long-term effects of the inferior olive destruction on the red nucleus activity, were studied in the rat following injection of 3-acetylpyridine. as soon as the olivary activity was suppressed, the discharge of the rubral units drastically decreased. then, they progressively recovered the control frequency during the first month, although a normal rubral activity was not restored up to 8 months. the hypothesis is advanced that the olivocerebellar system is essential to shape the activity of ... | 1988 | 2838039 |
| [digital subtraction angiography of acquired arteriovenous fistulas of the extremities]. | the signs of arterio-venous fistulae in the extremities have been evaluated by dsa in 20 patients. angiographic signs for the presence of a-v fistulae are the following findings: dilatation of the supplying artery, elongation of the supplying artery, solitary a-v aneurysm, angiomatous a-v aneurysm, reduced blood flow distal to the a-v fistula, early venous filling, development of a venous collateral circulation and demonstration of retrograde venous flow. angiography remains the method of choice ... | 2009 | 2836906 |
| insulin-like growth factor i binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver. | insulin-like growth factor-i (igf-i) in human hepatoma cells (hep-g2) has, in addition to its effect on cell growth, short-term metabolic effects acting through its own receptor. we have demonstrated that normal human hepatocytes, compared with hep-g2 cells, have virtually no igf-i binding sites. because the rate of growth is the major difference between the hepatoma and the normal liver, we asked if normal liver might express igf-i binding sites under physiologic growth conditions. indeed, wher ... | 1988 | 2832449 |
| nucleic acid sandwich hybridization in detection of hpv 16 dna: technique and its clinical application. | nucleic acid sandwich hybridization technique was used for detection of hpv 16 specific dna in cervical scrapes. alternating hpv 16-psti fragments were cloned into plasmid pbr322 and phage m13mp10. pbr322-clones were used as 32p-labelled probe reagents and the m13mp10 clones as catching reagents in the assay. the detection limit of the test proved to be 1-5 x 10(5) hpv 16 molecules per test. a weak cross reaction was seen with hpv 31 dna but not with the other types tested, e.g. hpv 6, 11, 18 an ... | 2010 | 2832436 |
| [functional paraganglioma (pheochromocytoma) in an aortico-pulmonary location]. | 2009 | 2815638 | |
| [differentiated changes in the activity of the sympathetic nerves induced by glycopenia in spontaneously hypertensive rats]. | 2-deoxy-d-glucose (2-dg) evokes an increase in the efferent discharge rate of the adrenal nerve in anesthetized rats and rabbits. a 63% increase in adrenal sympathetic nerve activity (adrsna) occurred within 15 min after 125 mg/kg 2-dg administration in alert animals, no changes being revealed in the renal sympathetic nerve activity (rensna), blood pressure (bp) or the heart rate (hr). additional administration of 375 mg/kg 2-dg (cumulative dose 500 mg/kg) led to an over 120% increase in the adr ... | 1989 | 2806664 |
| dual-column immunoassays using protein g affinity chromatography. | tandem protein g affinity and reversed-phase chromatography (rpc) columns, coupled with a switching valve, were used for on-line immunoassays of antibodies and antigens. columns with reversibly immobilized antibodies were prepared by adsorbing antibodies on the protein g column. following antigen capture in the immunoaffinity column, antigen-antibody complexes were desorbed, dissociated, and transferred to the rpc column where they were separated and quantified. this system was used to determine ... | 1989 | 2802148 |
| micropuncture localization of the natriuretic effect of interleukin 1. | interleukin 1 (il-1) has been demonstrated to elicit an increase in renal sodium excretion. this effect occurs in the absence of any increase in the filtered load of sodium, raising the possibility of an il-1-mediated decrease in tubule sodium reabsorption. to localize the nephron segment(s) responsible for the natriuretic effect of il-1, we performed micropuncture experiments on rats. intravenous il-1 administration caused a marked increase in sodium excretion that was not accompanied by change ... | 1989 | 2785767 |
| dissection of the prostatic apex for radical cystectomy and detubed ileocystoplasty. | 2007 | 2780674 | |
| subaortic stenosis associated with anomalous right ventricular muscle bundle and ventricular septal defect. | a rare case of biventricular outflow tract obstruction in the form of discrete subaortic membrane and hypertrophic anomalous right ventricular muscle bundle associated with ventricular septal defect is presented. | 2009 | 2777307 |
| rural nursing: developing the theory base. | many health care needs of rural dwellers cannot be adequately met through the use of existing nursing models alone but require unique approaches emphasizing the special needs of this population. the development of an integrated theory base for rural nursing is necessary. a retroductive approach, building upon both qualitative and quantitative research data, is being used to develop a theory of rural nursing. key concepts identified are: work beliefs and health beliefs; isolation and distance; se ... | 2009 | 2772454 |
| antibody responses and protection in mice immunized with herpes simplex virus type 1 antigen immune-stimulating complex preparations. | the formation of immune-stimulating complexes (iscoms) obtained by mixing the glycoside quil a with an antigen preparation derived from herpes simplex virus type 1 (hsv-1)-infected cell cultures using a zwitterionic detergent is described. the hsv-1 antigen preparation incorporated into iscoms elicited significantly greater antibody responses in mice than the same preparation administered together with aluminium hydroxide gel, and provided complete protection against hsv-1 or hsv-2 lethal, syste ... | 1989 | 2769234 |
| [ultrastructure of human adrenal glands at various periods of prenatal morphogenesis]. | as demonstrates the electron microscopical investigation of the adrenals in human embryos and fetuses 6--32-week-old, at the age of 10--12 weeks glomerular and fasciculo-reticular zones are already differentiating. subsequently, during following stages of the prenatal morphogenesis, when ultramicroscopical signs of the zonal belonging of cells and specific activity of steroid-synthesizing organells, the cortical reaction to the birth stress is manifested. installation of the cells of the medulla ... | 1989 | 2764742 |
| dexamethasone suppression test nonsuppression and tardive dyskinesia. | 2009 | 2763856 | |
| the frequency of alcoholism and alcohol related brain disorders in various regions of oslo city. an autopsy study. | the autopsy materials from the 5-year period 1983-1987 from ullevål and aker hospitals in oslo were reviewed. all cases with alcoholism were recorded and the histological sections were re-examined with regard to the presence of wernicke's encephalopathy and alcoholic cerebellar atrophy. the two materials were compared statistically in order to see whether any difference in the frequency of alcoholism and alcohol related brain disorders could be demonstrated between the geographic areas served by ... | 2009 | 2760752 |
| dose-response relationships regarding vitamin b-6 in elderly people: a nationwide nutritional survey (dutch nutritional surveillance system). | the dietary intake and biochemical status of vitamin b-6 in 476 apparently healthy dutch elderly people (aged 65-79 y), who were not using drugs known to affect vitamin b-6 metabolism, were evaluated. intake of vitamin b-6 per gram protein was related to biochemical data, namely plasma pyridoxal 5'-phosphate (plp) and cofactor stimulation of aspartate aminotransferase in erythrocytes (ast-ac). based on a cutoff point of 2.02 for ast-ac, approximately 9% of the elderly people not using vitamin b- ... | 2009 | 2756926 |
| identification by c-banding of two human prostate tumour cell lines, 1013l and du 145. | two human prostate carcinoma cell lines are easily distinguished by c-banding. du 145 has one metacentric chromosome with a large centromeric band, 1 metacentric and 2 acrocentric chromosomes with interstitial c-bands. the y chromosome was present in 48% and 42% of the cells at passages 83 and 106, respectively, whereas in 1013l only one metacentric chromosome contained distinct extra c bands--one at the centromere and one interstitially. the y chromosome was present in 72% of the cells at passa ... | 1989 | 2744886 |
| transferable 5-nitroimidazole resistance in the bacteroides fragilis group. | we report the characterization of a strain of bacteroides vulgatus, bv17, that exhibits a moderate resistance to 5-nitroimidazoles and carries plasmids of 4.5, 5, 7.7, and 56 kb. a genetic determinant involved in this resistance is carried by the 7.7 +/- 0.2-kb plasmid (pip417). this plasmid can be introduced and replicated in a sensitive strain of b. fragilis 638r by transformation or by conjugation. in the latter case, the transfer may involve mobilization by the 56-kb conjugative plasmid (pip ... | 1989 | 2740453 |
| closed intramedullary nailing of diaphyseal fractures of the femur. problems related to anatomical variations of the greater trochanter. | an examination of the radiographs of 100 normal femurs revealed an anatomical variation consisting of lateralization of the trochanteric mass in relation to the femoral diaphysis. this involves disalignment of the apex of the greater trochanter in relation to the medullary canal, with consequent complications during closed intramedullary nailing such as varus of the fracture segments, valgus of the nail, fracture of the medial cortex. since becoming aware of this anatomical variation and its pos ... | 2009 | 2737894 |
| degradation of intestinal glycoproteins by bacteroides vulgatus. | bacteroides vulgatus, isolated from a patient with crohn's disease, produced in gnotobiotic rats 7 constitutive enzymes that might be concerned with the degradation of intestinal glycoproteins. furthermore bacteroides vulgatus caused an almost complete loss of blood group antigenicity of the intestinal glycoproteins. enzymes with the potency to release toxic compounds from hepatic conjugates and plant glycosides, beta-glucuronidase and beta-glucosidase, respectively, were only detectable in smal ... | 1989 | 2721924 |
| u.s./japan cooperative cancer research program. proceedings of the united states-japan melanoma and skin cancer seminar on the biology and comparative features. november 13-15, 1987, tokyo. | 2009 | 2715649 | |
| comparative in vitro activity of cefoxitin, cefotaxime alone, and in combination with desacetylcefotaxime against the bacteroides species. | the agar dilution method was used to determine the inhibitory activity of cefotaxime (ctx) alone, desacetylcefotaxime (dctx) alone, ctx plus dctx, and cefoxitin against 74 clinical isolates of the bacteroides species recovered from diabetic patients with foot ulcers. the study concluded that the addition of dctx to ctx increased the inhibitory activity from 45% to 73% for all strains tested and from 50% to 81% among the 32 strains of bacteroides fragilis. this synergistic interaction against b. ... | 1989 | 2714070 |
| use of the glucose oxidase/peroxidase method for glucose assay leads to overestimation of the inhibition of gluconeogenesis by aminopyrine. | 4-aminoantipyrine strongly inhibits glucose determination by the glucose oxidase/peroxidase/dianisidine assay but does not interfere in the assay using glucose-6-phosphate dehydrogenase, hexokinase and atp. as a result, the inhibition of gluconeogenesis by aminopyrine reported to be 50-90% (bánhegyi, g., mandl, j., antoni, f. and garzó, t. (1987) biochim. biophys. acta 927, 406-416) is strongly overestimated and amounts to only 10-30%. | 1989 | 2713417 |
| protein kinase c is activated in glomeruli from streptozotocin diabetic rats. possible mediation by glucose. | glomerular inositol content and the turnover of polyphosphoinositides was reduced by 58% in 1-2 wk streptozotocin diabetic rats. addition of inositol to the incubation medium increased polyphosphoinositide turnover in glomeruli from diabetic rats to control values. despite the reduction in inositol content and polyphosphoinositide turnover, protein kinase c was activated in glomeruli from diabetic rats, as assessed by an increase in the percentage of enzyme activity associated with the particula ... | 1989 | 2708528 |
| cell type-specific expression of the human transferrin gene. role of promoter, negative, and enhancer elements. | transferrin (tf), the iron transport protein of vertebrate serum, is mainly synthesized in the liver. cis-acting dna elements required for liver-specific expression of the human tf gene were identified by transient and stable expression assays in human hepatoma (hepg2 and hep3b) and epithelial carcinoma (hela) cell lines. deletion analysis of the 5' dna sequences of the gene have defined four functionally different regions: (a) a cell type-specific promoter located between positions -125 and -45 ... | 1989 | 2708361 |
| design, expression, and crystallization of recombinant lectin from the garden pea (pisum sativum). | the propeptide form of the lectin from the garden pea (pisum sativum agglutinin) has been expressed in escherichia coli by attaching its cdna to an inducible promoter. by a number of criteria, including the ability to form dimers, hemagglutination titer, western blot, and enzyme-linked immunosorbent assay, the resulting propeptide molecule is virtually indistinguishable from the mature proteolytically processed lectin isolated from peas. preliminary crystallization experiments using the recombin ... | 1989 | 2708344 |
| when to use posts. | 2009 | 2698331 | |
| sluggish schizophrenia in the modern classification of mental illness. | the concept of latent schizophrenia was developed by e. bleuler (1911) and was further promoted in the studies of a number of research psychiatric schools of europe, the united states, japan, and other countries. in soviet psychiatry, there is a long-established tradition of studying "soft" forms of schizophrenia (kerbikov 1933; rozenshtein 1933; brukhanskii 1934). in the systematics of schizophrenia, developed by snezhnevsky (1969) and his colleagues, sluggish schizophrenia is viewed not as an ... | 2009 | 2696084 |
| the acid-etch retained rest for removable partial dentures. | this article will describe the techniques for composite and metal rests. it will also discuss a clinical follow-up of 18 patients who have had metal or composite rests in place from three to 18 months. | 2009 | 2691082 |
| [ultrasonographic evaluation of hepatic hematoma after biopsy]. | 2009 | 2690789 | |
| role of amino acids in modulating glucose-induced desensitization of the glucose transport system. | amino acids were found to play an integral role in modulating glucose-induced desensitization of the glucose transport system (gts). when adipocytes were treated for 6 h in a defined buffer containing 25 ng/ml insulin, 20 mm glucose, plus the 15 amino acids found in dulbecco's modified eagle's medium, we observed marked desensitization of the gts, manifested by a 60% decrease in maximal insulin responsiveness (mir) and a 2.5-fold reduction in insulin sensitivity. in contrast, little or no desens ... | 1989 | 2687266 |
| decompression surgery in graves' orbitopathy--a review of 14 years' experience at the orbita centrum, amsterdam. | 2008 | 2687051 | |
| differential diagnosis of patients with abnormal serum creatine kinase isoenzymes. | for the diagnosis of myocardial injury, particularly ami, ck-mb has become the gold standard. changing ck-mb activities in serially collected blood from patients with suggestive signs and symptoms of ami is almost pathognomonic for infarction. nevertheless, an increased ck-mb cannot be equated with ami owing to the many other types of inflammatory, traumatic, and miscellaneous forms of injury to the heart and the trace activities of ck-mb in skeletal muscle. other enzyme tests for ami are less e ... | 2009 | 2686905 |
| cancer of colon and rectum. | 2009 | 2686902 | |
| clinical studies of polymyalgia rheumatica. a proposal of diagnostic criteria. | a differential diagnosis of polymyalgia rheumatica (pmr) and rheumatoid arthritis (ra) can be difficult in elderly patients, especially at the prodromal phase of ra. furthermore, it was felt that there might be a diagnostic criteria for pmr specific to the japanese. accordingly, we have retrospectively studied the pmr patients who had come to our hospital, for making a diagnostic criteria. we especially stressed the distinguishing of pmr from ra in elderly patients. the criteria proposed are as ... | 2009 | 2681899 |
| a century of change in neurosurgery at johns hopkins: 1889-1989. | neurosurgical admissions to the johns hopkins hospital during the first year of its existence, the first and last years of harvey cushing's practice, the last years of walter dandy's practice, the last years of earl walker's tenure, and the current neurosurgical case load are reviewed. sixteen patients with neurosurgical problems were admitted during the first year of the hospital's existence. in the first year of harvey cushing's staff appointment, 38 neurosurgical patients were admitted. infec ... | 2009 | 2681565 |
| pathogenicity of the bacteroides fragilis group. | the bacteroides fragilis group is one of the most important pathogens in polymicrobial infections. the distribution of the different members of the b. fragilis group in clinical infections varies. bacteroides fragilis accounts for 63 percent of all the group isolates, bacteroides thetaiotaomicron for 14 percent, bacteroides vulgatus and bacteroides ovatus for seven percent each, bacteroides distasonis for six percent and bacteroides uniformis for two percent. all members of the group induced bac ... | 1989 | 2679351 |
| in vitro susceptibility and in vivo efficacy of antimicrobials in the treatment of bacteroides fragilis-escherichia coli infection in mice. | cefamandole, cefoxitin, cefotetan, ceftizoxime, imipenem plus cilastatin, and ampicillin plus sulbactam were compared in the eradication of subcutaneous abscess in mice caused by bacteroides fragilis group organisms and escherichia coli alone or in combination. the abscesses were examined 5 d after inoculation. b. fragilis group reached log10.1-11.0 organisms per abscess and e. coli log11.6-12.5. imipenem plus cilastatin significantly reduced (in 6.9-10.6 logs) the number of e. coli and all memb ... | 1989 | 2677161 |
| craniofacial trauma. | the treatment of combined major dislocations of the face and skull requires a craniofacial team consisting of a plastic maxillofacial surgeon, a neurosurgeon, an anesthesiologist, and radiologists. the best results can only be achieved at the primary intervention both from a functional and an esthetic standpoint. careful preoperative clinical and radiologic examinations are mandatory to reach these high goals. in primary repair, the cranial approach aims at constructing "a monobloc bone flap" to ... | 2009 | 2672614 |
| dna alkylation and formation of dna interstrand cross-links by potential antitumour 2,5-bis(1-aziridinyl)-1,4-benzoquinones. | a series of 3,6-substituted 2,5-bis(1-aziridinyl)-1,4-benzoquinone derivatives was shown to alkylate calf thymus dna and to form dna interstrand cross-links. alkylation and cross-link formation were enhanced after electrochemical reduction of the compounds and increased with lower ph in the ph range from 4.5 to 8.0. reduction especially shifts the ph at which cross-linking and alkylation occurs to higher values, which are more physiologically relevant. this shift is probably caused by the increa ... | 1989 | 2663197 |
| otospongiosis and sodium fluoride. a clinical double-blind, placebo-controlled study on sodium fluoride treatment in otospongiosis. | the effect of sodium fluoride treatment in patients with otospongiosis has been evaluated in a prospective clinical double-blind, placebo-controlled study of 95 patients. the results showed a statistically significant greater deterioration of hearing loss in the placebo group than in the group actively treated with 40 mg of sodium fluoride daily. these results support the view that sodium fluoride can change otospongiotic, active lesions to more dense, inactive otosclerotic lesions. | 2009 | 2655462 |
| the role of transplantation in liver disease. | liver transplantation is rapidly emerging as the most effective treatment pathway for a growing number of acute and chronic liver disease states. indications and contraindications to transplant are undergoing continuous revision and clarification as experience is accrued in the expanding number of treatment centers. for some disorders such as primary biliary cirrhosis, sclerosing cholangitis, and chronic active hepatitis with cirrhosis, the role of transplantation in patient management is obviou ... | 2008 | 2648619 |
| clinical aspects of liver atrophy. | the implications of selective liver atrophy in the management of hepatobiliary disease have only recently been recognised and discussed. this editorial focuses on clinical aspects of liver atrophy together with some relevant experimental data. | 2009 | 2646358 |
| [questions and answers on urological care. management of a balloon catheter which cannot be removed smoothly]. | 2008 | 2630750 | |
| purification and characterization of a new hydrolase for conjugated bile acids, chenodeoxycholyltaurine hydrolase, from bacteroides vulgatus. | a new hydrolase for conjugated bile acids, tentatively named chenodeoxycholyltaurine hydrolase, was purified to homogeneity from bacteroides vulgatus. this enzyme hydrolyzed taurine-conjugated bile acids but showed no activity toward glycine conjugates. among the taurine conjugates, taurochenodeoxycholic acid was most effectively hydrolyzed, tauro-beta-muricholic and ursodeoxycholic acids were moderately well hydrolyzed, and cholic and 7 beta-cholic acids were hardly hydrolyzed, suggesting that ... | 1989 | 2628421 |
| omental autoimplantation of splenic tissue and intravenous pneumococcal challenge. a comparative study in rats. | splenectomized subjects show a higher incidence of myocardial ischemia and of overwhelming post-splenectomy infection (opsi). it is doubtful that implanted splenic tissue guarantees an adequate protection from opsi. the histological characteristics and the capacity of protection from opsi of two models of omental autoimplantation of splenic tissue in rats were examined. the implanted splenic tissue offers a significant protection from pneumococcal sepsis, even though there is no relation between ... | 1989 | 2628385 |
| fifty hours for the poor? | 2008 | 2612144 | |
| fifty hours for the poor? | 2008 | 2612144 | |
| [analysis of the nursing factors responsible for expanding the sphere of daily activities of patients with parkinson's disease]. | 2008 | 2612141 | |
| [analysis of the nursing factors responsible for expanding the sphere of daily activities of patients with parkinson's disease]. | 2008 | 2612141 |