Publications

mechanisms of immunity in tuberculosis.		1979	113763
mycobacterium leprae and phenoloxidase activity.	our earlier studies indicated that the enzyme o-diphenoloxidase was absent in mycobacterium leprae separated from depromatous human tissues. at that time the bacilli were not available from any other source. the existence or absence of this enzyme in m. leprae recovered from infected armadillo tissues were reinvestigated. the intact cells which were metabolically active, failed to oxidize dopa. likewise, dopa and its derivatives were not oxidized by the enzymatically active cell-free preparation ...	1978	113650
lysosomal enzymes and microbicidal capacity of activated macrophage.	a relation was sought between acid phosphatase contents and the presence of tubercle bacilli inside the peritoneal exudate cells (pec) of normal guinea pigs and those immunized with bcg. this was done to investigate the role lysosomal enzymes play in the microbicidal capacity of the cell. in both normal and immune animals tubercle bacilli were present only in those pec that contained acid phosphatase. cells without acid phosphatase did not contain bacilli. thus, only activated cells ingested bac ...	1978	113649
[a long-term observation on previously treated cases of pulmonary tuberculosis retreated with rifampicin for more than six months (author's transl)].		1979	113607
purification of antibodies to bacterial antigens by an immunoadsorbent and a method to quantify their reaction with insoluble bacterial targets.	a combination of procedures was employed to develop a radioimmunoassay which quantified the binding of antibodies to antigens of either intact propionibacterium acnes or to antigens of insoluble extracts derived from the bacteria. reactive antibody populations were purified by use of bacterial immunoadsorbents which were prepared by coupling p. acnes to diethylaminoethyl cellulose. binding of antibodies was detected with [125i]staphylococcal protein a ([125i]spa) and optimal conditions for the a ...	1979	113462
influence of dimethyl sulfoxide (dmso) on restoring sensitivity of mycobacterial strains resistant to chemotherapeutic compounds.		1979	113379
effects of panax ginseng extracts on the growth of mycobacterium tuberculosis h37rv.		1979	113372
immunization against schistosoma mansoni in rhesus monkeys and the requirement of activation of both cell-mediated and humoral mechanisms.	when groups of rhesus monkeys were pretreated with bcg plus hyperimmune serum from monkeys with chronic schistosomiasis or with dialyzable transfer factor from uninfected monkeys plus hyperimmune serum and were challenged with 1,500 cercariae of schistosoma mansoni, the mean worm burdens were significantly lower than that of untreated controls. pretreatment with neither bcg alone nor corynebacterium parvum plus a membrane antigen of adult worms of s. mansoni affected susceptibility. neither lymp ...	1979	113342
delayed hypersensitivity in ambystoma mexicanum.		1979	113261
isoniazid inhibition of the synthesis of monounsaturated long-chain fatty acids in mycobacterium tuberculosis h37ra.	isoniazid inhibited c(24) and c(26) monounsaturated fatty acid synthesis in mycobacterium tuberculosis h37ra. time courses of this inhibition and that of mycolic acid synthesis were similar.	1979	112917
hydroxylamine sensitivity and salt tolerance in screening and identifying mycobacteria.	hydroxylamine sensitivity offered no advantage over p-nitrobenzoic acid in distinguishing between tubercle bacilli and other (opportunist and non-significant) mycobacteria. it was of limited use in identification procedures. salt tolerance assisted in the identification of strains which may be mycobacterium triviale and m. chelonei var borstelense.	1979	112745
tuberculin hypersensitivity following bcg vaccination in brisbane school children.	seven hundred and fifty brisbane school children were tuberculin tested, in paired groups, with purified protein derivatives of mycobacterium tuberculosis, bovis, bcg and avium. reaction to avian ppd were stronger than to any of the others used. this finding may be of some importance in interpreting the variation in protection afforded by bcg vaccination.	1979	112744
the flotation method for detection of tubercle bacilli in sputum smears.	both the flotation smear examination and culture techniques yielded results for detection of tubercle bacilli which were superior to either direct smear examination or to examination of smear from liquefied or liquefied-centrifuged sputum specimens.	1979	112743
pathology of tuberculosis.		1979	112687
thoracic tuberculosis: laboratory aspects.		1979	112686
thoracic tuberculosis: clinical aspects.		1979	112685
[combined infection with yersinia pseudotuberculosis and mycobacterium tuberculosis as a rare cause of obstructive icterus].		1979	112451
[inhibitory effect of tuberculoglycoprotein on lysosomal enzyme activity (author's transl)].		1979	112316
[l-phase growth of mycobacteria. 2. consideration on the survival of tubercle bacillus in caseous lesion (author's transl)].		1979	112315
status of drug resistance of mycobacterium tuberculosis strains isolated from hospitalized patients in lucknow.		1979	112054
tuberculous cervical lymphadenitis.		1979	111794
diagnosis and management of tuberculosis.		1979	111269
tuberculosis of the cns presenting as mass lesions.		1979	111206
brain tuberculoma. diagnosis and treatment.		1979	110891
immunoregulation in infection caused by mycobacterium tuberculosis: the presence of suppressor monocytes and the alteration of subpopulations of t lymphocytes.	this study was designed to characterize qualitative and quantitative alterations, occurring before and during chemotherapy, in the mononuclear cells of patients with infections caused by mycobacterium tuberculosis. a hemolytic plaque-forming (pfc) assay indicated that the production of antibody to sheep red blood cells by pokeweed mitogen (pwm)-stimulated lymphocytes was suppressed in treated and untreated patients as compared with that in normal adult donors (p less than 0.001). the removal of ...	1979	110887
three types of mycolic acid from mycobacterium tuberculosis brévanne: implications for structure-function relationships in pathogenesis.	saponification of the chloroform-soluble wax from mycobacterium tuberculosis brévanne led to the isolation of three classes of mycolic acid containing characteristic functional groups along the methylene backbone: type alpha (two cyclopropane rings); type beta (methoxyl, methyl, and cyclopropane); and type gamma (ketone, methyl, and cyclopropane). the structures of these acids were elucidated principally by mass spectrometry. the high mass region of the keto mycolate is presented showing the mer ...	1979	110779
antigenic differences between extracts of actively replicating and synchronized resting cells of mycobacterium tuberculosis.	protein extracts were prepared from aerobically replicating cells of mycobacterium tuberculosis and from synchronized non-replicating cells derived from the sediments of non-agitated cultures. although both preparations share a number of antigens, the extracts of the non-replicating cells also contain antigenic components that are not shared by the replicating cells, and which can be isolated and visualized by immunoaffinity chromatography and immunoelectrophoretic techniques.	1979	110697
immunobiology and species distribution of mycobacterium tuberculosis antigen 5.	the immunobiology and mycobacterial species distribution of immunoabsorbent affinity chromatography-purified mycobacterium tuberculosis antigen 5 have been studied. in delayed hypersensitivity skin tests, antigen 5 was nearly equipotent with tuberculin-purified protein derivative in sensitized guinea pigs. in vitro, antigen 5 was capable of stimulating the production of migration inhibitory factor by cultured lymphocytes from sensitized guinea pigs and humans. antigen 5 stimulated thymidine inco ...	1979	110696
diagnosis of tuberculosis: routine cultures of bronchial washings are not indicated.	during a five-year period, cultures of bronchial washings for mycobacterium tuberculosis were obtained almost routinely (859 of 1,012 bronchoscopic examinations.). this practice proved costly, and the diagnostic yield was extremely low. only three cases were diagnosed solely by this method (0.35 percent). five other cases were false-positive. additionally, 39 patients with known active pulmonary tuberculosis had false-negative cultures of bronchial washings; 13 of these 39 patients were receivin ...	1979	110539
tuberculosis in oriental immigrants: a study in military dependents.	tuberculosis in oriental immigrants is likely to be resistant to therapy with certain drugs. in 73 military dependents with positive cultures for tuberculosis who immigrated from six asian countries, the tuberculosis was found to be resistant to isoniazid in 58 percent (42 patients), to streptomycin in 36 percent (26 patients), to p-amino-salicylic acid in 14 percent (ten patients), to rifampin in 7 percent (five patients), and to ethambutol in 7 percent (five patients). despite the presence of ...	1979	110538
"routine."--a practice to be abjured.		1979	110537
[tuberculosis in patients deceased of renal insufficiency in a long-term hemodialysis program].	eight cases of tuberculosis were seen in a series of patients dying of renal insufficiency after having been subjected to a long-term haemodialysis. in 5 cases mycobacterium tuberculosis was successfully cultivated (4 were typed as human, 1 as bovine). in 5 cases the disease affected mainly the lymph nodes, not the lungs. in 3 of these a prevalence of abscessing specific granulomas with the presence of leucocytes was noted on microscopical examination. the findings have been regarded as possibly ...	1979	110471
u.s. public health service cooperative trial of three rifampin-isoniazid regimens in treatment of pulmonary tuberculosis.	a total of 822 patients with newly diagnosed pulmonary tuberculosis were assigned randomly to one of 3 daily rifampin-isoniazid (rif-inh) regimens: 450, 600, or 750 mg of rif in combination with 300 mg of inh. after an initial 20 weeks of therapy with rif-inh, patients recieved 300 mg of inh and 15 mg of ethambutol (emb) per kg of body weight for either 12 or 18 months after their sputum cultures became negative. the rate of bacteriologic conversion of sputum among the 3 rif-inh regimens was com ...	1979	110184
pulmonary manifestations of mycobacterium intracellularis.	pulmonary manifestations in 114 patients with at least two sputum cultures positive for m. intracellularis, no history of any kind of tuberculosis, and not other potential pathogen are described. even with these stringent diagnostic criteria, seven patients had normal chest radiographs and another seven had reticulonodular-appearing disease without a definite focus of infection. in the other 100 patients, 92% had infiltrates in the apical and/or posterior segments of the upper lobes, and 88% had ...	1979	110071
[incidence of drug resistance of mycobacterium tuberculosis].		1979	109992
[sensitivity of mycobacterium tuberculosis to antitubercular agents].		1979	109991
the value of the routine guinea-pig test.		1979	109980
further studies of mycobacteriophage 33d (warsaw) for differentiation of bcg from m. bovis and m. tubeculosis.	mycobacteriophage 33d (warsaw) was used to differentiate bacille calmette-guerin (bcg) strains from m. bovis and m. tuberculosis. known strains as well as clinical strains of bcg were used in the study. single plaque isolations and adsorption studies demonstrated that phage 33d (warsaw) did not adsorb to bcg cultures.	1979	109978
direct migration inhibition test with leukocytes as indicator of mycobacterial antigens in the human body.	in 32 patients with newly detected pulmonary tuberculosis positive on smear and culture, included in a controlled clinical trial, a significant correlation between diminishing inhibition of leukocyte migration (induced by ppd) and reduction of mycobacterial population in the sputum during the course of chemotherapy has been demonstrated. the changes of mycobacterial population in the host have been assessed in two ways: an indirect assessment was made from the time taken to achieve sputum smear ...	1979	109977
[lymphocyte transformation test in patients with active tuberculosis and in healthy subjects frequently exposed to m tuberculosis].		1979	109821
fatal tuberculosis in young children.	three young children with advanced cavitary pulmonary tuberculosis died between 1974 and 1978. two of the patients had tuberculous meningitis as well. all diagnoses were verified at autopsy; however, all tuberculin skin tests were negative. these instances emphasize the difficulty of establishing the diagnosis of tuberculosis in young children. tuberculosis should be considered in the differential diagnosis of cavitary chest disease in young children, even those with negative tuberculin skin tes ...	1979	109806
confusion of legionella pneumophila and mycobacterium tuberculosis.		1979	109752
[effect of various disinfectants (phenol derivatives, quaternary ammonium compounds, aldehydes and chloramine) on human type tubercle bacilli sensitive and resistant to antibacillary drugs].		1979	109709
the effect of pretreatment with bcg on infection with schistosoma mansoni in mice and monkeys.		1978	109612
demonstration of tuberculostearic acid in sputum from patients with pulmonary tuberculosis by selected ion monitoring.	selected ion monitoring was used to detect tuberculostearic acid (10-methyloctadecanoic acid) in sputum from patients with pulmonary tuberculosis. the specimens were autoclaved, lyophilized, extracted, and methanolysed before being subjected to thin-layer chromatography and injected into the gas chromatograph/mass spectrometer. tuberculostearic acid could be detected in five of six tuberculous sputum specimens containing acid-fast rods detectable by light microscopy of ziehl-neelsen stained smea ...	1979	109465
immunodiffusion studies of various structural preparations from mycobacterial cells.	various structures and other preparations from mycobacterial cells were analyzed by immunodiffusion. the preparations were obtained from four strains referred to the species mycobacterium bovis (bcg), mycobacterium fortuitum, mycobacterium phlei and mycobacterium smegmatis. they represented cell walls (cw), culture filtrates (cf), artificially disintegrated cell material (xp), protoplasms (pp), crude ribosomes (cr), ribosomal 50s subunits (50s), ribosomal 30s subunits (30s), ribosomal 16s core p ...	1979	109402
immunodiffusion studies of ribosomes in classification of mycobacteria and related taxa.	ribosomal preparations consisting of crude ribosomes (cr), 30s subunits (30s) and 16s core particles (16s) from four strains of the species mycobacterium bovis (bcg), mycobacterium fortuitum, mycobacterium phlei and mycobacterium smegmatis were analyzed by immunodiffusion technique for taxonomical purposes. the ribosomal preparations tested contained several interspecies cross-reacting precipitinogens. the number of precipitinogens demonstrated at the homologous reactions was generally larger th ...	1979	109401
prophylactic effect of bcg cell-wall skeleton on the tumor induction by 7,12-dimethylbenz[a]anthracene in mice: strain difference.	prophylactic effect of repeated intravenous administrations of oil-attached bcg cell-wall skeleton (bcg-cws) on the induction of tumor by 7,12-dimethylbenz[a]anthracene (dmba) was investigated in various strains of mice. the subcutaneous injection of dmba emulsified in oil induced squamous cell carcinoma in almost all of the strains of mice. treatment of c57bl/6, balb/c, and ddo strains with bcg-cws with appropriate route and timing resulted in the retardation of dmba-induced tumor development m ...	1979	109342
biochemical changes in avian tissues during infection.	major sources of error in studies of diet--infectious disease interactions relate to failure 1) to define the stage of a disease cycle; and 2) to determine the extent of disease involvement at time of sampling. the former can be determined from clinical and biochemical observations from time of inoculation to recovery or mortality; the latter can be calculated from indexes obtained from histological preparations, changes in body temperatures, and other clinical symptoms, including weight loss an ...	1979	109321
[criteria of resistance of some antibiotics and chemotherapeutics for strains of mycobacterium tuberculosis isolated in czechoslovakia. cycloserin, ethionamide, pyrazinamide, rifampicin, and ethambutol (author's transl)].		1979	109213
purification and properties of valyl-trna synthetase from mycobacterium smegmatis.	valyl-trna synthetase from mycobacterium smegmatis has been purified over 1200-fold by conventional techniques as well as affinity chromatography on valyl-aminohexyl sepharose columns. the purified preparation is homogeneous by electrophoretic and immunologic criteria. the enzyme is a tetramer of approximate molecular weight of 120,000, composed of a single type of subunit. the synthetase exhibited maximal activity between 35--40 degrees c and ph 6.8--7.0. the pure enzyme though stable for sever ...	1979	109126
primary drug resistance in children. drug susceptibility of strains of mycobacterium tuberculosis isolated from children during the years 1973 through 1977 at the kings county hospital center of brooklyn.	a continuing study of the frequency of primary drug resistance among children treated at the kings county hospital center of brooklyn during the years 1973 through 1977 showed a high incidence of primary drug resistance to isoniazid (8.8 per cent) and to streptomycin (12.3 per cent). in contrast, there were no strains resistant to cycloserine, viomycin, ethambutol, or rifampin, and only one of 57 strains (1.8 per cent) was resistant to ethionamide, and one (1.8 per cent) was resistant to para-am ...	1979	109024
the booster phenomenon in serial tuberculin testing.	to determine the frequency, magnitude, and causes of the booster phenomenon in tuberculin testing, a total of 1,478 employees from 10 hospitals throughout the united states received sequential intradermal tests using ppd-t. in addition, approximately 70 per cent were initially tested with ppd-g. boosting was found in all age groups tested, but increased with age. it occurred as soon as one week after an initial tuberculin test, but rarely before that time. the boosted reactions were apparently c ...	1979	109023
miliary tuberculosis in children. clinical and laboratory manifestation in 19 patients.	the clinical course of 19 children with miliary tuberculosis was studied. complaints were nonspecific and included fever, anorexia, weight loss, and night sweats. although all but one child had a miliary infiltrate visible on the chest roentgenogram, only 13 had a positive reaction to the purified protein derivative of the tuberculin test at admission to the hospital. outcome was excellent unless the child also had tuberculous meningitis or was in a far advanced state of the disease. miliary tub ...	1979	108996
drug sensitivity of m. leprae isolated from leprosy patients administered dds for long period of time.	drug sensitivity was tested using liquid medium on three stains isolated from the subcutaneous nodules of l-type patients who have long been administered dds alone. the results revealed that the first strain was resistant to dds up to the concentration of 1.0 microgram/ml suggesting as if it were dds dependent or enhanced strain, whereas the second strain was completely sensitive to dds even at the lowest concentration of 0.01 microgram/ml suggesting possible inactivation of this drug in the hos ...	1978	108909
induction kinetics of delayed hypersensitivity towards mycobacterium tuberculosis and m. avium: analysis of cross-reactions elicited by ppd-tuberculin and ppd-b.		1978	108772
[effect of carbon dioxide on the inoculability of mycobacterium tuberculosis from pathological material].		1979	108674
mycobacterium scrofulaceum infection in erythrocebus patas monkeys.	mycobacterium scrofulaceum was cultured from two of seven tuberculin reactors in a group of 12 erythrocebus patas monkeys. one monkey reacted atypically to 0.1 ml of 2.5 mg veterinary tuberculin after having shown no reaction to four previous tests administered at 2-week intervals. the reaction consisted of edema with no induration or erythema at 24 hours and was completely dissipated at 36 hours. responses to additional tests using veterinary tuberculin (2.5 mg) and mycobacterium bovis purified ...	1979	108474
[tuberculosis and changes in the tissue lipids].		1979	108447
[bactericidal effect of rifampicin on resting tubercle bacilli in vitro (author's transl)].		1979	108446
tuberculosis of the mandible presenting as 'lumpy jaw'.		1979	108413
thrombocyte migration and the release of thrombocyte inhibitory factor (thrif) by t and b cells in the chicken.	the elaboration of various inhibitory factors by sensitized lymphocytes has been reported for both mammals and birds. until recently, the ability of the b cell to elaborate these had been questioned by a number of investigators. we have demonstrated the release of a lymphocyte inhibitory factor from the avian thymus and bursal lymphocyte. the avian thrombocyte is active in haemostasis as well as being a phagocytic cell. we have demonstrated that the ability of the thrombocyte to migrate, signifi ...	1979	108206
immunosuppression by mycobacterial arabinomannan.		1979	108041
benign presentation of tuberculous meningitis.		1979	107992
[epidemiological and clinical aspects of drug-resistant tubercle bacilli in children treated in the years 1961--1976].		1979	107515
immunologic functions and in vitro activation of cultured macrophage tumor lines.	five murine monocyte of macrophage tumor lines adapted to culture were characterized for differentiated properties. they ingested zymosan and latex beads, bore receptors for immunoglobulin and complement, synthesized lysozyme (most of which was secreted), and produced granulocyte colony-stimulating activity, either spontaneously or inducibly. some of the lines also mediated phagocytosis and exocytosis of red blood cells (rbc) and lysis of tumor targets, dependent on the presence of specific anti ...	1978	107454
[short course chemotherapy for pulmonary tuberculosis with duration for 6 months after sputum negative conversion. (report 1)--report of the 19--20th a series of controlled trial of chemotherapy--(author's transl)].		1979	107362
[effect of amikacin on experimental tuberculosis of mice (author's transl)].		1979	107361
[sputum positive conversion among retreatment cases with pulmonary tuberculosis converted to negative by the use of rifampicin (author's transl)].		1979	107360
isoprenoid quinones in the classification of coryneform and related bacteria.	menaquinones were the only isoprenoid quinones found in 85 of the 95 coryneform bacteria examined. dihydromenaquinones having nine isoprene units were the main components isolated from corynebacterium bovis, from other glutamic acid-producing strains, and from arthrobacter globiformis and related species. dihydromenaquinones with eight isoprene units were found in brevibacterium linens, the remaining corynebacterium species and strains probably belonging to the genus rhodococcus. tetrahydromenaq ...	1979	107269
acetylated methylmannose polysaccharide of streptomyces griseus. locations of the acetyl groups.	the positions of esterification of the 4 to 5 acetyl residues in the acetylated methylmannose-containing polysaccharide from streptomyces griseus have been established by the methyl replacement technique, wherein ester substituents are specifically replaced with methyl ether substituents. the newly incorporated methyl groups were distinguished from 3-o-methyl groups by the use of polysaccharide containing radioactively labeled endogenous methyl groups. the positions of methyl group localization ...	1979	107171
pericarditis due to mycobacterium tuberculosis and mycobacterium fortuitum: a case report.	in this case study, pericarditis results from mycobacterium tuberculosis and mycobacterium fortuitum. both organisms were isolated from three different clinical specimens: a pericardial fluid, pericardium, and a thoracentesis fluid. a mixed mycobacterial culture was initially suspected upon examining ziehl-neelsen stained smears prepared from the primary cultures following seven to ten days of incubation. dilutions and subcultures were subsequently performed, confirming the presence of two diffe ...	1979	106725
cross-reactions between mycobacteria. ii. crossed immunoelectrophoretic analysis of soluble antigens of bcg and comparison with other mycobacteria.	cross-reactions between mycobacterium bovis bcg and various other mycobacteria, nocardia asteroides, corynebacterium pyogenes and listeria monocytogenes were studied by incorporating antibodies against these bacteria in the intermediate gel of a crossed immunoelectrophoretic system with bcg antigen and anti-bcg antibodies. in the bcg reference system forty-four distinct antigenic components were recorded, of which thiryt-three cross-reacted with mycobacterium tuberculosis, twenty-five with m. av ...	1979	106465
[study of the milk of nursing mothers with tuberculosis for mycobacterium tuberculosis].		1979	106387
[microbiological studies in the clinical picture of osteoarticular tuberculosis].		1979	106386
[biological characteristics of the specific and nonspecific microflora in osteoarticular tuberculosis].		1979	106385
[effect of temperature fluctuations in sending pathological material on the inoculability of mycobacterium tuberculosis].		1979	106384
[comparative study of methods for the bacterioscopic diagnosis of tuberculosis and of methods for determining drug sensitivity].		1979	106383
[decrease of isoniazid-resistant mycobacterium strains].		1979	106354
[persisters and chemotherapy in tuberculous infection (author's transl)].		1978	106180
cell-mediated immunity on secretory surfaces.		1978	105574
[the use of mycobacteria in the estimation of the concentration of antibiotics, antimycotics and antituberculotics (author's transl)].	the possibility of using the rapid resistance test to determine the levels of antibiotic, antimycotic and antituberculotic drugs is systematically investigated. as a rule the incubation time reduced to seven days for tubercel bacilli results in a lower inhibitor concentration (mic) than with other microbiological methods used in tuberculosis diagnostics due to a lower inactivation of the drugs. the mic of antibiotics and antituberculotics is found between 0.02 and 15 microgram/ml; for penicillin ...	1978	105479
[prognostic value of isolation of drug-resistant mycobacterium tuberculosis].		1978	105475
[detection of mycobacterium tuberculosis with the parallel use of various methods].		1979	105353
[bacteriostatic activity of the blood in pulmonary tuberculosis and its clinical significance].		1979	105352
[action of iodophoric disinfectants and chlorhexidine-containing preparations on human-type tubercle bacilli].		1979	105345
effect of mycobacterial water-soluble adjuvant (maf3) on the immune response of guinea pigs to the hapten-carrier conjugates.		1978	105230
[adjuvant activity and antigenicity of maf3 determined by the lymphocyte blastogenesis (author's transl)].		1978	105172
bovine tuberculosis.		1978	105166
the effect of cortisone on the accumulation, activation, and necrosis of macrophages in tuberculous lesions.	rabbits were injected intramuscularly with cortisone acetate (2 mg/kg) on alternate days. six days after the first injection these rabbits and controls were injected intradermally in multiple sites with bcg (the vaccine strain of tubercle bacillus). periodically, over the next 2 months, the resulting lesions were measured and surgically biopsied, and the animals were tuberculin-tested. macrophage activation in the bcg lesions was evaluated histochemically by staining for beta-galactosidase activ ...	1978	104930
recovery from tuberculous meningitis.		1979	104758
[is bacteriophage typing of mycobacterium tuberculosis of practical value?].		1978	104757
growth characteristics of atypical mycobacteria in water and their comparative resistance to disinfectants.	with the increasing significance of group iv atypical mycobacteria as etiological agents in a variety of infections, studies were conducted to determine their growth capabilities in water and their comparative resistance to disinfectants used to decontaminate hospital equipment. isolates of mycobaterium chelonei (tm strains) from peritoneal fluids of patients and peritoneal dialysis machines were able to multiply in commercial distilled water, with generation times at 25 degrees c ranging from 8 ...	1978	104656
a continuing survey of tuberculosis primary drug resistance in the united states: march 1975 to november 1977. a united states public health service cooperative study.		1978	104647
cell-mediated and humoral immune responses of cattle to brucella abortus, mycobacterium bovis, and tetanus toxoid: immunization of the fetus.		1978	104646
cell-mediated and humoral immune responses of cattle to brucella abortus, mycobacterium bovis, and tetanus toxoid: evaluation of immunization and assay techniques.	a concentration of 2.5 x 10(-5) m 2-mercaptoethanol (2-me) added to the medium in lymphocyte blastogenesis assays increased both the uptake of [3h]thymidine in unstimulated lymphocyte cultures and the probability of detecting antigen-sensitized cattle. the use of 2-me did not cause lymphocytes from unsensitized cattle to react positively in blastogenesis assays. a crude brucella lysate prepared from brucella abortus strain 19 was compared with a well-characterized brucella protein allergen prepa ...	1978	104645
radiographic manifestations of pulmonary mycobacterium kansasii infections.	the radiographic characteristics of 187 pristine cases of pulmonary mycobacterium kansasii infection are reviewed. the cases were selected from a total of 309 patients with two positive sputum cultures. all but three of the 187 patients had pulmonary disease. the progenitive focus of disease almost always involved the upper lobes, the right side (72%) more often than the left (50%). upper lobe disease began posterior to the trachea in every case. only one patient had disease that originated in a ...	1978	104602
[leprosy].		1978	104538
isolation of m. leprae using semi-synthetic solid agar medium.	the primary isolation of m. leprae from leprous nodules was carried out using agar slant prepared by solidifying the basic compositions of m-y series to confirm the reproducibility of the preliminary studies. results revealed that l-feb-75 strain represented thin membraneous growth from about 20th week and it crept up the culture tube wall at about 30th week of incubation at 37 degrees c. l-jun-75 strain, on the other hand, exhibited numerous, white and rough colonies of submiliary size on vario ...	1978	104536
stimulating effect of leucine on the growth of m. leprae.	m-y 16j agar slant was prepared by modifying m-y 14b which has hitherto been used most widely in our experiments by increasing the amount of na pantothenate and adding leucine, and the growth stimulating effect was investigated referring to the foregoing subculture experiments. the results revealed that the growth of m. leprae was stimulated remarkably in the primary isolation quite similarly to the subculture. this seemed to be resulted from stimulated biosynthesis of fatty acids by the leucine ...	1978	104535