Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| ioversol clinical safety summary. | the authors evaluated double-blind comparative and open-label clinical trials in 1,186 patients who received ioversol to evaluate the safety and efficacy of ioversol, a new nonionic low-osmolality contrast medium, at iodine concentrations of 32%, 24%, and 16%. the results indicate that ioversol was well tolerated in all patients and showed fewer adverse effects than conventional ionic agents. the diagnostic efficacy of ioversol was comparable to both conventional and other nonionic agents with r ... | 2009 | 2687200 |
| a novel maturation marker for human sertoli cells. | the maturation of sertoli cells at puberty is critical for the initiation and maintenance of spermatogenesis. little is known about the factors which control sertoli cell maturation. we have examined sertoli cells in testicular specimens from 44 subjects, ranging in age from 6 months to 67 years, for reactivity with a mouse monoclonal antibody (m2a) using the immunoperoxidase reaction. we found positive reactivity with prepubertal but not postpubertal sertoli cells, suggesting that the antigen d ... | 1989 | 2687179 |
| multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen state. | this report describes the clinical results obtained from a multicentre experience of the use of autologous and allogenic cultured human epidermal cells in the treatment of partial and full skin thickness burns. a laboratory has been organized to supply cultured epithelium to burns units in different cities. from may 1986 to december 1988, 58 patients with an age range of 1 to 59 years, and with burns covering between 7 and 95 per cent of the body surface area, have been treated. graftable cultur ... | 1989 | 2686683 |
| recent advances in gastrointestinal malignancy. | 2008 | 2686527 | |
| recent advances in gastrointestinal malignancy. | 2008 | 2686527 | |
| [modern theoretical and practical conceptions of the epidemiology of shigellosis]. | 1989 | 2686310 | |
| [problems in the epidemiology and prevention of intestinal infections]. | 1989 | 2686152 | |
| volvulus of the gallbladder. report of two cases and review of the literature. | torsion or volvulus of the gallbladder is a rare cause of acute cholecystitis. although it has been reported in all age groups, it is most commonly seen in the elderly. with our increasingly aged population, it behooves the clinician to keep this entity in mind when treating the older patient with abdominal pain. we present two cases of torsion of the gallbladder and review the clinical and pathological aspects of this disease. | 2009 | 2685538 |
| interspecies gene transfer in vivo producing an outbreak of multiply resistant shigellosis. | in 1983, a small outbreak of infections caused by a previously unrecognized multiply-drug-resistant shigella flexneri 3a strain occurred on the hopi indian reservation. the index patient, a diabetic woman with recurrent escherichia coli bacteriuria on prophylactic trimethoprim/sulfamethoxazole (tmp/smz) therapy, was hospitalized with concurrent e. coli urinary tract infection and shigellosis. both e. coli isolated from her urine and s. flexneri isolated from her stool were resistant to ampicilli ... | 1989 | 2685126 |
| complications of acute pancreatitis. | in 1925, sir berkeley moynihan stated that "acute pancreatitis is the most terrible of all the calamities that occur in connection with the abdominal viscera." the case of m.h. clearly reflects the accuracy of that statement. it should be pointed out that through the exceptional, dedicated care provided by all members of the health care team, a young woman whose predicted mortality approached 100 percent was restored to her previous state of good health, and has since delivered a healthy baby gi ... | 2009 | 2684542 |
| current concepts in the treatment of peptic ulcer disease: a case-oriented approach, part 1. | 2009 | 2683706 | |
| construction and evaluation of a double mutant of shigella flexneri as a candidate for oral vaccination against shigellosis. | based on studies on the genetic and molecular basis of shigella flexneri invasive properties, we have constructed and evaluated a double mutant of s. flexneri serotype 5 for utilization as a live attenuated oral vaccine against shigellosis. the first mutation, icsa, blocks intracellular spread of bacteria as well as cell-to-cell infection. it affects the capacity of the invasive pathogen to form large abscesses in epithelia. the second mutation, iuc, eliminates production of the siderophore aero ... | 1989 | 2683460 |
| effects of sound on fetal cerebral glucose utilization. | 2009 | 2683108 | |
| thymotaxin, a chemotactic protein, is identical to beta 2-microglobulin. | thymotaxin, an 11-kilodalton protein chemotactic for rat bone marrow hematopoietic precursors, was purified from media conditioned by a rat thymic epithelial cell line. the nh2-terminal sequence of thymotaxin was identical to that of rat beta 2-microglobulin (beta 2m). antibodies to beta 2m removed thymotaxin activity from the fraction containing the 11-kilodalton protein. chemotactic activity was observed with rat plasma beta 2m, human beta 2m, and mouse recombinant beta 2m, further supporting ... | 1989 | 2683083 |
| a comparison of structural features of the walls of coronary arteries from 10 different species. | the intimal thickness of the coronary arteries of humans less than 20 years of age was compared with that 9 other species. it was found that humans were unique amongst the species studied in showing substantial intimal thickening at an early age. the intimal thickening was associated with defects of the internal elastic lamina (iel), which in humans were not repaired, but which in other species were associated with an effective reduplication of the iel. this reformed iel appeared in other specie ... | 1989 | 2682490 |
| [coexistence of abdominal aortic aneurysm and intraabdominal malignancy; two case reports]. | we experienced two cases of abdominal aortic aneurysm which had intra-abdominal malignancy (early gastric cancer). case 1 was a 72 year-old man who was treated by two-stage operation of them. gastrectomy was performed about 7 months prior to the aneurysmectomy. case 2 was a 70 year-old man who was diagnosed both lethal diseases, renal dysfunction, chronic respiratory failure and multiple ventricular arrhythmia. he was treated by one-stage operation and was discharged with no complications. coexi ... | 1989 | 2682201 |
| mucoepidermoid carcinoma arising in a lymphoepithelial cyst--report of a case and review of the literature on branchiogenic carcinoma. | a 59-year-old japanese man who had recently noticed a gradual enlargement in a nodule located in the left anterior part of his neck was admitted for surgical treatment. the histopathological features of the resected tumor were consistent with a typical lymphoepithelial cyst, however, the inner surface epithelium of the cyst showed histological transition to mucoepidermoid carcinoma, which was partially invading the cyst wall. despite clinical efforts in a systemic search, no primary lesions whic ... | 1989 | 2681906 |
| sonographic and pathological staging of patients with clinically localized prostate cancer. | we evaluated 64 patients with clinically localized prostate cancer (on the basis of rectal examination, serum acid phosphatase, bone scan and pelvic computerized tomography scan) by transrectal sonography before radical prostatectomy. of the 48 patients with histologically proved localized prostate cancer sonography overstaged the disease in 5 (10%) and correctly staged it in 43 (90%). all overstaged cancer patients were scanned after either prostatic biopsy (4) or transurethral prostatectomy (1 ... | 2009 | 2681836 |
| 45 years ago--the pioneer health centre, peckham. | 2009 | 2681768 | |
| regulation of plasminogen activators and their inhibitors in rheumatic diseases: new understanding and the potential for new directions. | over the past several years there has been a rapid expansion in our understanding of the fibrinolytic system. this includes knowledge of the components, availability of recombinant reagents and a better understanding of the regulation of fibrinolysis in health and disease. disturbances in the regulation of the balance between fibrin deposition and removal have been implicated in a number of inflammatory diseases including certain rheumatic diseases. this overview summarizes our knowledge of the ... | 2009 | 2681762 |
| parenteral gold therapy for rheumatoid arthritis: a treatment whose time has gone. | 2009 | 2681757 | |
| mechanism of action of gnrh-induced oocyte maturation. | 1989 | 2681744 | |
| the presence of nicotine on root surfaces of periodontally diseased teeth in smokers. | there is a growing body of scientific evidence to support the concept that the use of tobacco products significantly contributes to the progression of periodontal disease or is detrimental to healing following periodontal therapy. several studies have shown toxic effects of nicotine on peripheral circulation and the immune response. the purpose of the present study was to identify and compare the quantity of nicotine present on root planed and nonroot planed surfaces of teeth from smokers. twent ... | 1989 | 2681674 |
| indicators of spontaneous and stimulated nitroblue tetrazole test of polymorphous-nuclear leucocytes in acute dysentery patients. | 140 healthy individuals and 93 sick with acute dysentery were subjected to an examination by spontaneous and by bacterial preparations stimulated reaction with nitroblue tetrazole (nbt test). indicators in healthy persons were normal in the spontaneous, and increased in the nbt test, stimulated by bacterial preparations. indicators of the spontaneous nbt test in patients with acute dysentery were raised with a maximum in the period of early convalescence. stimulation by a live shigella culture-- ... | 1989 | 2681402 |
| herpes simplex infection associated with pemphigus vulgaris. case report and literature review. | a 55-year-old man had an 8-week history of oral ulcers. studies revealed concurrent pemphigus vulgaris and active herpes simplex infection. there have been seven previous case reports of this association, and these are reviewed. | 1989 | 2681299 |
| orientation of reaction center complexes from rhodobacter sphaeroides in proteoliposomes and the effect of o-phenanthroline on electrogenesis during primary photochemical reaction. | the orientation of rhodobacter sphaeroides reaction center complexes (rc complexes) in proteoliposomal membranes was investigated by a direct electrometric method. conditions were found that allow monitoring of only that rc complex fraction that is oriented with its donor side to the inner part of the proteoliposome. it is shown that o-phenanthroline, an inhibitor of electron transfer between primary (qa) and secondary (qb) quinone acceptors, can also inhibit the photoinduced qa reduction. the e ... | 1989 | 2681179 |
| anxiety and physical illness in the elderly. | the prevalence of anxiety disorders increases with advancing age. unfortunately, the diagnosis of anxiety in elderly patients is often reached only after everything else has been ruled out. elderly patients with clinical anxiety often present with physical complaints that mask the underlying anxiety disorder. recognition and management of anxiety disorders in the elderly must be prompt to interrupt the cycle of anxiety-depression, physical illness, and other stresses. | 2009 | 2681174 |
| a 101-kilodalton heme-binding protein associated with congo red binding and virulence of shigella flexneri and enteroinvasive escherichia coli strains. | the ability of shigella flexneri to bind congo red or hemin is associated with virulence. a 101-kilodalton (kda) protein responsible for this phenotype (crb+) in s. flexneri was identified by a tetramethylbenzidine staining procedure which detects heme-protein complexes in polyacrylamide gels. labeling of cell-surface polypeptides with 125i revealed that the 101-kda heme-binding protein is expressed on the cell surface. expression of the protein was regulated by growth temperature and was found ... | 1989 | 2680975 |
| the mhc trans-species hypothesis: in the discussion period. | rather than attempting to summarize what i might have said in my presentation at the symposium honoring professor avrion mitchison and thus merely expounding on data that have in the meantime been published elsewhere, here i will answer some of the criticisms that have been meted out at the trans-species hypothesis in the discussion period. i fancy that av will savour this spiced-up birthday present more than he would its conventional version. | 2008 | 2680919 |
| optimized insulin delivery: achievements and limitations. | 2007 | 2680670 | |
| increase of alveolar pressure reduces systemic-to-pulmonary bronchial blood flow in humans. | we studied the effect of positive alveolar pressure (pa) on systemic to pulmonary bronchial blood flow, q?? in humans. the q?? was measured during total cardiopulmonary bypass as the volume of blood accumulating in the left heart. this blood was vented by gravity from the left heart via a cannula introduced in the right upper pulmonary vein and advanced to the lowest portion of the left heart. in group a (n = 10) the qbr(s-p) was measured for 25 to 95 min with constant pa (4.0 +/- 0.2 cm h2o, me ... | 2008 | 2680319 |
| converging and diverging pathways in polypeptide hormone action. | 2008 | 2680229 | |
| latvian dentists in the 1990s: a born-again profession? | 2009 | 2679989 | |
| status of rotator cuff sonography. | 2009 | 2678244 | |
| transcription by rna polymerase i stimulates mitotic recombination in saccharomyces cerevisiae. | the recombination-stimulating sequence hot1 is derived from the ribosomal dna array of saccharomyces cerevisiae and corresponds to sequences that promote transcription by rna polymerase i. when inserted at a chromosomal location outside the ribosomal dna array, hot1 stimulates mitotic recombination in the adjacent sequences. to investigate the relationship between transcription and recombination, transcription promoted by hot1 was directly examined. these studies demonstrated that transcription ... | 1989 | 2677675 |
| torsion--treatment indications. | rotational problems, when outside the normal range, are referred to as torsional deformity. these deformities are relatively common in infancy and childhood, generally resolve spontaneously with growth, and rarely persist into adult life. there are few situations in which treatment is necessary. (1) rigid metatarsus adductus that does not resolve during the first six months should be corrected by casting. the long leg cast is most effective, as it controls the rotation of the tibia. with the tib ... | 2009 | 2676305 |
| severe acquired aplastic anemia in children: 11-year experience with bone marrow transplantation and immunosuppressive therapy. | we reviewed the management and outcome of severe acquired aplastic anemia in 36 patients younger than 18 years old between march 1977 and june 1987. in most patients, no cause could be found. the best therapeutic results were achieved with allogeneic bone marrow transplantation from histocompatible related donors (14 patients), with a cure rate of 79%. bone marrow transplantation from mismatched related donors was attempted in two patients and failed in both. immunosuppression using antithymocyt ... | 2009 | 2675660 |
| lymphocyte homing. | the phenomenon of "homing" is discussed with respect to patterns of lymphocyte circulation and the molecules on the surface of both endothelium and lymphocytes that mediate this process. in addition, the data are analysed in the context of a model for lymphocyte homing. | 1989 | 2675225 |
| studies on interactions of endotoxin with factors of the contact system of plasma. | 1989 | 2675058 | |
| identification of shigella invasion genes by isolation of temperature-regulated inv::lacz operon fusions. | penetration and multiplication within cells of the human colonic epithelium are hallmarks of shigella spp. pathogenicity. shigella spp. virulence is regulated by growth temperature. strains phenotypically virulent when grown at 37 degrees c are phenotypically avirulent when grown at 30 degrees c. the number of genes involved in shigella spp. pathogenicity and how many virulence genes are temperature regulated are unknown. to facilitate the study of temperature-regulated virulence in shigella spp ... | 1989 | 2674014 |
| clinical & bacteriological profiles of shigellosis in calcutta before & after an epidemic (1984-87). | patients below 5 yr of age, hospitalised for shigellosis over a period of four years (1984-87), were studied. during the epidemic of bacillary dysentery (1984) isolation of different shigella spp. as well as shigella dysenteriae type 1 was high. decreased isolation of sh. dysenteriae type 1 and increased isolation of sh. flexneri was observed during post-epidemic years (1985-87). isolation of different shigella spp. was always above 25 per cent from patients with dysentery and greater than 7 per ... | 1989 | 2674001 |
| morphogen gradients and the control of body pattern in insect embryos. | the basic body plan of insects is set up in response to determinants initially localized at the anterior and posterior poles of the egg. early in development, these determinants give rise to a series of morphogen gradients which in turn trigger a cascade of molecular signals determining the body pattern. this signalling process is outlined and recent experiments testing the roles of these gradient systems in determining anterior and posterior pattern are described. the results of these experimen ... | 2009 | 2673685 |
| computer-assisted structural analysis of polysaccharides with an extended version of casper using 1h- and 13c-n.m.r. data. | the computer program casper, used in the structural analysis of polysaccharides composed of repeating units, has been extended. the extended version uses either unassigned 1h- or 13c-n.m.r. chemical shifts or the complete unassigned c,h-correlation spectrum, and can predict the structure of linear and branched oligo- and poly-saccharides. the number of possible structures, consistent with sugar and methylation analysis, can be decreased by the use of 1jc,h and 3jh,h values. the database, which c ... | 1989 | 2673508 |
| synthesis of prostacyclin and thromboxane a2 by rat gastric mucosa. comparison of 1,6-dimethyl-4-oxo-1,6,7,8,9,9a-hexahydro-4h-pyrido (1,1-a)-pyrimidine-3-carboxamide and cimetidine. | the production of prostacyclin (pgi2) and thromboxane a2 (txa2) was studied in an indometacin-induced ulcer model in rats. the specific activities of prostacyclin synthetase and thromboxane synthetase as well as the tissue content of these prostaglandins were determined. the anti-ulcer effect of cimetidine and a novel agent, i.e. 1,6-dimethyl-4-oxo-1,6,7,8,9,9a-hexahydro-4h-pyrido(1,1-a)-pyrimidine-3- carboxamide (chinoin-127) was compared in this respect. the indometacin treatment shifted the b ... | 1989 | 2673252 |
| malignant hyperthermia. potential crisis in patient care. | 2009 | 2673033 | |
| electron microscopy for the rapid detection and identification of viruses from clinical specimens. | the advantages of using electron microscopy for rapid diagnosis of virus infection from clinical specimens, for identification of virus isolates with unusual properties, and for monitoring endogenous agents in cell cultures are illustrated by several actual cases that have occurred over the years. the importance of using morphological characteristics of viruses for initial identification is emphasized. | 2009 | 2672617 |
| adverse effects of amiodarone. pathogenesis, incidence and management. | amiodarone is an extremely effective antiarrhythmic agent for the treatment of both life-threatening ventricular arrhythmias and refractory supraventricular tachyarrhythmias. subjective minor side effects are common with amiodarone but rarely require discontinuation of therapy and are often handled by dose reduction. serious end-organ toxicity, including pulmonary fibrosis and drug-induced hepatitis, have been the most common indications for discontinuing amiodarone therapy in these patients. | 2009 | 2671595 |
| interleukin-1 potentiates granulopoiesis and thrombopoiesis by producing hematopoietic factors in vivo. | in vivo administration of recombinant human interleukin-1 beta (rhu il-1 beta) selectively enhanced the recovery from granulocytopenia and thrombocytopenia caused by whole body irradiation, in a dose dependent manner. since il-1 itself in vitro had no colony-stimulating activity (csa), we studied whether il-1 can produce hematopoietic factors in vivo, which in turn will promote granulopoiesis and thrombopoiesis. serum from il-1 injected mice showed marked granulocyte/macrophage csa (gm-csa), but ... | 1989 | 2671565 |
| putative start codon ttg for the regulatory protein virg of the hairy-root-inducing plasmid pria4. | the nucleotide sequence of the virg gene for a transcriptional activator on the agropine-type hairy-root-inducing plasmid pria4 was determined. the sequence contained one possible open reading frame. the gene product with a molecular size of 26.5 kda was identified by an escherichia coli coupled-transcription-translation system using cloned virg plasmids as templates. however, neither an atg nor a gtg start codon which could give rise to such a protein was identified in the nucleotide sequence. ... | 1989 | 2670679 |
| asthma and chronic bronchitis in africa. evidence from epidemiologic studies. | 2008 | 2670473 | |
| oviducal storage of spermatozoa in the turkey: its relevance to artificial insemination technology. | 1. this paper addresses questions concerning the role of oviducal sperm selection and storage in the relative inefficiency of turkey reproduction. 2. before the onset of egg production, the turkey has the biological potential to store spermatozoa in its oviduct for periods up to 5 weeks; after the onset of production fewer spermatozoa are retained by the oviduct. 3. a better understanding of the biological mechanisms which regulate sperm selection and storage in the turkey oviduct is necessary t ... | 1989 | 2670069 |
| liver disease associated with exposure to 1,1,1-trichloroethane. | 1,1,1-trichloroethane is a halogenated hydrocarbon solvent commonly used in industry because of its supposed lack of hepatotoxicity. nonetheless, animal studies performed by several independent groups have shown the solvent to induce fat deposition, vacuolar degeneration, and centrilobular necrosis, changes similar to those seen after exposure to carbon tetrachloride, albeit of a much reduced magnitude, in animals exposed to the agent. four patients with fatty liver disease whose work entailed s ... | 1989 | 2669664 |
| macrophages: current views on their differentiation, structure, and function. | macrophages are large mononuclear phagocytes that represent the major differentiated elements of the mononuclear phagocytic system. they arise from distinct progenitors in the bone marrow, and their immediate precursors, the monocytes, emigrate from the vascular compartment into many tissues and organs where they develop into mature macrophages. the latter display diverse morphological and functional characteristics, depending on the environmental stimuli that they receive. this phenotypic heter ... | 2009 | 2669295 |
| [bacillary dysentery--1987]. | 1989 | 2669032 | |
| fungistatic activity of miconazole against candida albicans in relation to ph and concentration of nonprotonated drug. | at less than 10(-5) m, miconazole (mcz) exerts a fungistatic effect on candida albicans, presumably by interfering with ergosterol biosynthesis. the imidazole moiety of mcz is subject to protonation (pka approximately 6.5). based on pka and greater water solubility of protonated (mczh+) versus nonprotonated (mczo) drug, fungistatic action ought to be markedly affected by environmental ph, but apparently it is not. in this report growth phase, ph, and concentrations of mcz and mczo have been stud ... | 1989 | 2668754 |
| molecular cloning and characterization of chromosomal virulence region kcpa of shigella flexneri. | in shigella flexneri, in addition to several well-recognized plasmid-borne virulence loci, at least three genetic loci implicated in pathogenesis have been recognized on the chromosome. to understand more about the pathogenesis of bacillary dysentery at a molecular level, the genetically recognized but previously unidentified kcpa region (one of the chromosomal regions near pure) was cloned and sequenced. a single translatable open reading frame encoding a 12310 dalton protein corresponding to t ... | 1989 | 2668687 |
| purification, crystallization, and preliminary x-ray diffraction studies of the flavoenzyme mercuric ion reductase from bacillus sp. strain rc607. | the flavoenzyme mercuric ion reductase from bacillus sp. strain rc607 was purified by dye-ligand affinity chromatography. the protein was crystallized from solutions of high ionic strength, and one of the two crystal forms obtained has proven suitable for x-ray diffraction studies. preliminary analysis showed that these crystals belong to the tetragonal space group 1422. the unit cell dimensions are a = b = 180.7 a; c = 127.9 a. the diffraction pattern extends to better than 3 a resolution. crys ... | 1989 | 2668287 |
| internalization of shigella flexneri into hela cells occurs without an increase in cytosolic ca2+ concentration. | pathogenic shigella flexneri invades epithelial cells through directed phagocytosis. the role of intracellular free calcium ([ca2+]i) as a signal for this process was tested. no variation in the [ca2+]i could be detected by using the fluorescent indicator fura 2 to measure the [ca2+]i in hela cells during the invasion process. in addition, neither clamping nor maximal decreasing or increasing of the [ca2+]i of hela cells had any effect on their susceptibility to invasion. these data demonstrate ... | 1989 | 2668195 |
| detection and treatment of gastroesophageal reflux disease. | the diagnosis of gerd requires the thoughtful evaluation of a patient's symptoms and clinical course. in young patients with classical reflux symptoms in the absence of untoward complications such as structure, bleeding or pulmonary aspiration, antireflux treatment can be instituted without the need for diagnostic testing. a large number of patients will demonstrate a good clinical response to medical therapy. the diagnostic challenge arises when symptoms of reflux masquerade as cardiac and pulm ... | 2009 | 2668171 |
| mechanics of the healed meniscus in a canine model. | the mechanical behavior of the intact canine stifle joint was studied, using a surgical model of meniscal injury and repair. thirty-eight animals were divided into five study groups: group s received only a sham arthrotomy (without a meniscal incision), groups p13 and p26 received peripheral medial meniscal incisions, and groups r13 and r26 received radial medial meniscus incisions. all meniscal incisions were repaired anatomically with absorbable suture. groups p13 and r13 were sacrificed at 13 ... | 1989 | 2667375 |
| percutaneous nephrostomy in pyonephrosis. | a series of 76 pyonephrotic kidneys in 73 patients were drained by percutaneous nephrostomy (pn) tube and examined to evaluate the contribution of this technique to the treatment of pyonephrosis. in 71 patients, clinical symptoms disappeared 24-48 h after the procedure. two patients died from sepsis subsequent to anuria and underlying malignancy. once the acute phase had remitted, interventional procedures were carried out in 39 cases, and constituted the definitive therapy in 36. in 32 cases, e ... | 1989 | 2667249 |
| captopril test in screening hypertensive patients. | 2009 | 2666599 | |
| use of monoclonal antibodies to type shigella flexneri in bangladesh. | a panel of 10 mouse and rat monoclonal antibodies specific for different type- and group-specific o-antigenic determinants of shigella flexneri lipopolysaccharide was used to serotype 240 isolates of s. flexneri from bangladesh. three immunoglobulin m antibodies were used in a direct slide agglutination test; seven immunoglobulin g antibodies were absorbed to staphylococcus aureus and used in a coagglutination assay. all but 13 of the isolates could be serotyped by using the monclonal antibodies ... | 1989 | 2666435 |
| [long-term results following breast reconstruction]. | a ten-year experience of breast reconstruction (br) at the gustave-roussy institute (paris) provides material for a long-term analysis of carcinologic and cosmetic results. carcinologic results have been studied in a group of 120 breast reconstructions which was matched to a group of 120 mastectomies without br. no statistical difference was observed both for the overall survival and the disease-free survival in both groups. the percentage of local recurrences in the reconstructed breast was inf ... | 2004 | 2666356 |
| [results in microsurgical carotid artery endarterectomy]. | 100 consecutive carotid endarterectomies were performed by a microscopic technique with monitoring of cerebral perfusion by transcranial doppler sonography and eeg. no additional cerebral deficits occurred in this series. perioperative mortality due to medical complications occurred in 2 instances. during the average follow-up period of 15 months, 1 patient suffered a lethal cerebral infarction ipsilateral to the operated carotid artery and 1 patient a contralateral minor stroke. 2 patients died ... | 2009 | 2665064 |
| france: a focus on the new reproduction. | 2009 | 2663772 | |
| indicator dilution time-activity curves demonstrated by rapid magnetic resonance imaging techniques and paramagnetic contrast agent. | indicator dilution time-activity curves are demonstrated using magnetic resonance imaging (mri) as the detector and a paramagnetic contrast agent as the indicator. manganese chloride was injected into a flow phantom. the nuclear magnetic resonance (mr) intensity was measured downstream. several flow rates were used. the observed mr intensity decreased as the paramagnetic indicator passed through the imaging plane. the qualitative changes of the mr intensity decrease varied in accordance with ind ... | 2008 | 2663765 |
| plasmid-associated adherence of shigella flexneri in a hela cell model. | the initial interaction of shigella flexneri with hela cells was studied at 4 degrees c, a temperature that inhibits parasite-directed endocytosis. it was found that invasive strains were 10-fold more adherent to hela cells than were isogenic, noninvasive strains which had lost a 140-megadalton plasmid. adherent strains were also more hydrophobic than were nonadherent strains. | 1989 | 2663729 |
| congo red-mediated regulation of levels of shigella flexneri 2a membrane proteins. | the ability of shigella spp. to bind congo red from agar medium is generally correlated with their virulence properties. we used a metabolically active culture of shigella flexneri 2a to determine the effect of congo red on its membrane protein profiles. virulent s. flexneri grown in the presence of congo red at 37 degrees c showed increased levels of three proteins with mrs of 43,000, 58,000, and 63,000 (43k, 58k, and 63k proteins) in the sarkosyl-soluble membrane fractions. the observed phenom ... | 1989 | 2663721 |
| chloroplast and nuclear genomes of chlamydomonas reinhardtii share homology with escherichia coli genes for dna replication, repair and transcription. | most of the cpdna genes studied to date are genes encoding elements of the photosynthetic apparatus and translational machinery. much less is known about genes encoding the polypeptides involved in transcription, cpdna replication, recombination and repair. the similarities between bacterial and some cpdna genes were exploited to identify some of these chloroplast genes using bacterial probes. probes derived from the escherichia coli genes dnaa, reca, uvrc, transcriptional factor rho, and rpoc w ... | 1989 | 2663186 |
| elimination of malignant clonogenic breast cancer cells from human bone marrow. | autologous bone marrow transplantation is a promising approach to the treatment of breast cancer but is at present limited to patients without bone marrow metastases. to eliminate malignant clonogenic breast cancer cells from normal human bone marrow, immunomagnetic separation has been combined with chemoseparation using 4-hydroperoxycyclophosphamide. breast cancer cell lines have been mixed with a 10-fold excess of irradiated human bone marrow from normal donors. mixtures have been incubated wi ... | 1989 | 2663144 |
| lineage-specific gene rearrangement/deletion: a nonconservative model. | for the lymphocytic descendants of the hematopoietic differentiation pathway, characteristic gene rearrangements result in deletions of significant portions of chromosome regions specifying lymphocyte-specific gene products on either or both chromosomes of each involved pair. molecular mechanisms facilitating the rearrangement/deletion events have been elegantly and fruitfully elaborated in the years since the first documentation of their occurrence by hozumi and tonegawa (n. hozumi and s. toneg ... | 1989 | 2663139 |
| [biological properties of bacteria of the species shigella flexneri]. | some biological properties of s. flexneri have been studied. the strains of this bacterial species have been shown to produce dnaase in 98.8 +/- 0.77% of cases and rnaase in 97.4 +/- 1.5% of cases. the capacity for the positive reaction with congo red as early as after 24-hour incubation in the thermostat has proved to be characteristic of s. flexneri (91.1 +/- 3.6%). if stored at 4 degrees c in semiliquid agar, s. flexneri cultures have been found to retain their capacity for producing the abov ... | 1989 | 2662686 |
| a french research programme: santé-maladie-société (1984-1988). | 2009 | 2662421 | |
| inhibition of proteoglycan synthesis alters extracellular matrix deposition, proliferation, and cytoskeletal organization of rat aortic smooth muscle cells in culture. | arterial proteoglycans have been implicated in several important physiological processes ranging from lipid metabolism to regulation of smooth muscle cell growth. vascular smooth muscle (vsm) cells are the major producers of proteoglycans in the medial layer of blood vessels. to study functional consequences of alterations in vsm proteoglycan metabolism we used 4-methylumbelliferyl-beta-d-xyloside to inhibit proteoglycan synthesis in primary and early passage cultures of rat aortic smooth muscle ... | 1989 | 2661564 |
| renal allograft rejection: possible involvement of lymphokine-activated killer cells. | human renal allograft tissue was recovered at transplant nephrectomy from three patients with irreversible loss of graft function. this tissue was disaggregated and separated into two fractions on the basis of particle size. fraction 1 contained glomeruli and developed a mixed outgrowth containing adherent epithelial and mesangial cells after a limited period of culture. fraction 2 contained fragments of renal tubules and produced monolayers of tubular epithelial cells during culture. a populati ... | 1989 | 2661417 |
| electropherotyping of plasmid dna of different serotypes of shigella flexneri isolated in bangladesh. | one hundred and twenty-five shigella flexneri strains, isolated during january-december 1984, at the dhaka treatment centre of the international centre for diarrhoeal disease research, bangladesh, were serotyped using absorbed rabbit antisera specific for all type- and group-factor antigens, as well as a group of ten mouse and rat monoclonal antibodies. electropherotypes of the plasmid deoxyribonucleic acid (dna) were also determined. s. flexneri 2a was the predominant serotype followed by 3b, 1 ... | 1989 | 2661251 |
| [biliary peritonitis after hepatic biopsy: favorable course with conservative medical treatment]. | in a 53-year-old woman a percutaneous liver biopsy was performed with tru-cut to study persistent hypertransaminasemia. the patient did not present extrahepatic cholestasis. immediately after biopsy the patient had a picture of biliary peritonitis that evolved favorably with conservative medical treatment, including hemodynamic resuscitation, antibiotic therapy, analgesic treatment and monitoring by the resuscitation service. a review is made of the literature on this complication of liver biops ... | 2009 | 2660206 |
| evaluation of the first 60 cases of poly hema posterior chamber lenses implanted in the sulcus. | flexible lenses allow folding and inserting through a small incision. using faulkner's forceps, 60 hydrogel lenses were implanted in the sulcus through a 3.5 mm pocket incision following phacoemulsification. mean follow-up was six months. the lens was suitable for the procedure when it was properly handled. when it was not, untimely unfolding or tears occurred, necessitating prolonged maneuvering in the eye or sometimes replacement of the lens which caused increased trauma. though functional res ... | 2009 | 2659769 |
| [studies on urinary c-peptide excretion in normal children and children with insulin-dependent diabetes mellitus]. | in 115 normal children (3 to 14 years old) and 143 children with insulin-dependent diabetes mellitus (6 to 15 years old), the urinary c-peptide immunoreactivity) was measured for evaluation of the pancreatic b cell function. the urinary c-peptide excretions during o-gtt corresponded to the change of serum c-peptide levels in normal children (n = 27) and the mean value of the excretions in younger children was significantly low. age did not significantly affect basal serum c-peptide levels (ng/ml ... | 2009 | 2659621 |
| the enteric immune response to shigella antigens. | mucosal immunity to some enteropathogens occurs naturally following infection. by learning how to optimize initiation of the mucosal immune response it will be possible to develop vaccines against a wide variety of enteropathogens and their toxic products. in the past few years, we have examined stimulation of the mucosal response to shigella antigens. we have found that the mucosal memory response to shigella lps can be stimulated by oral immunization with live, but not with killed shigella. th ... | 1989 | 2659270 |
| oral shigella vaccines. | 1989 | 2659269 | |
| [determination of shigella antigens in the feces of people, immunized with enteral vaccine prepared from s. flexneri antigen]. | the dynamic determination of the presence of the specific antigen and its activity in the excreta of humans subjected to enteral immunization with vaccine prepared from s. flexneri antigen was made in the agglutination test and neutralization test with the use of, respectively, antibody and antigenic erythrocyte diagnosticums. in the feces and urine of the vaccinees antibodies occurred less commonly and, as a rule, they were less active than those detected in dysentery patients at the correspond ... | 1989 | 2658436 |
| inoculum size in shigellosis and implications for expected mode of transmission. | 1989 | 2656880 | |
| [pemphigus vegetans, a rare variant of pemphigus vulgaris]. | pemphigus vegetans is a variant of pemphigus vulgaris with different clinical manifestations. diagnosis may be difficult because of the varied presentations. a 46-year-old woman with this condition had been treated for behcet's disease because of oral lesions. on admission, prior to dermatological consultation, she was thought to have an infectious disease. the diagnosis of pemphigus vegetans was confirmed by histological and immunofluorescence studies. | 2008 | 2656429 |
| [pemphigus vegetans, a rare variant of pemphigus vulgaris]. | pemphigus vegetans is a variant of pemphigus vulgaris with different clinical manifestations. diagnosis may be difficult because of the varied presentations. a 46-year-old woman with this condition had been treated for behcet's disease because of oral lesions. on admission, prior to dermatological consultation, she was thought to have an infectious disease. the diagnosis of pemphigus vegetans was confirmed by histological and immunofluorescence studies. | 2008 | 2656429 |
| [treatment of cerebral hemorrhage]. | 2008 | 2656221 | |
| applications of immunocytochemistry to diagnostic cytopathology. | immunohistochemical technique is now successfully applied to the cytologic materials. this review article describes details of staining procedures for immunocytochemistry at both light and electron microscopic levels. the clinical application of the technique includes aspiration biopsy cytology for breast lesions, thyroid lesions, lymph nodes, the nervous system, and others. the establishment of carcinoma cells in the body fluid by the demonstration of carcinoembyronic antigen (cea) and the esta ... | 2009 | 2656146 |
| role of prolactin and luteinizing hormone in regulating timing of implantation in the spotted skunk. | the western spotted skunk exhibits an obligate delay of implantation lasting 200-220 days. the pituitary is essential for luteal activation. the corpora lutea, in turn, secrete the hormones necessary for blastocyst implantation. two experiments were designed to determine which pituitary hormones are responsible for increasing luteal activity and induction of implantation. forty-two pregnant skunks with delayed implanting blastocysts were treated as follows: 13 served as untreated controls, 6 rec ... | 2009 | 2655721 |
| control of diarrheal diseases. | the tremendous advances made in the control of diarrheal diseases in the past few years indicate what more can be achieved. even though the lives of an estimated three quarters of a million children are being saved each year, over three million children are still dying from readily preventable diarrheal disease. the challenge is to build on the successes thus far, to learn from experience, to promote changes in health habits that will prevent diarrhea, and to make all of these activities sustain ... | 1989 | 2655632 |
| studies with antibodies to cultured rat glomerular epithelial cells. subepithelial immune deposit formation after in vivo injection. | to investigate the role of glomerular epithelial cell (gec) membrane proteins in the in situ formation of subepithelial immune deposits, the authors raised a rabbit antiserum against gec that had been grown in culture (anti-gec). by indirect immunofluorescence (if) on normal rat kidney, anti-gec stained proximal tubular brush border (bb). after intravenous injection into animals, granular glomerular capillary wall staining for igg was present by ie and subepithelial immune deposits were identifi ... | 1989 | 2655461 |
| dopplersonographic diagnosis of subclavian steal in infants with coarctation of the aorta and interrupted aortic arch. | in two newborns with severe coarctation of the aorta and interrupted aortic arch, subclavian-steal was shown by angiocardiography. in both children pulsed doppler recordings were obtained in the cerebral arteries: normal forward flow during systole and diastole could be shown in the anterior cerebral arteries, both internal carotid arteries, the basilar artery and the right vertebral artery. in the left vertebral artery in both infants a negative flow indicating backflow from the brain could be ... | 2009 | 2654852 |
| [a case of immediate fertility restoration following childbirth]. | we report an unwanted pregnancy following immediately after fulltime childbirth. we could not find previous reports of this nature in international literature. women who give bottle-feeding are even more liable to early return of ovulatory cycles than women who give breastfeeding. if a puerpera has vaginal bleeding (not lochia), there is an increased risk of ovulation as well as of endometritis. it is no longer acceptable to take impossibility to conceive immediately after delivery for granted: ... | 2009 | 2654662 |
| melanin chemistry and melanin precursors in melanoma. | 2009 | 2654299 | |
| t-lymphocyte clones responsive to shigella flexneri. | t lymphocytes from a patient with shigella flexneri dysentery and postdysenteric reactive arthritis were cloned by limiting dilution with recombinant interleukin-2 and a strain of s. flexneri different from that which had infected her. five of eight clones produced proliferated in response to the shigellae used to generate the clones. the response required irradiated syngeneic blood mononuclear cells as antigen-presenting cells. one such clone, mc12, proliferated in response to both the shigella ... | 1989 | 2654177 |
| total body irradiation: single dose, fractions, dose rate. | 2009 | 2653510 | |
| androgen-regulated gene expression. | while a great deal of knowledge on the mechanisms of steroid hormone regulated gene expression now exists, specific information relating to androgens is lacking. a number of experimental systems have been developed and show promise as models for molecular studies of androgen regulation. further development of these models must address the issue of whether or not the androgen receptor behaves similarly to other steroid receptors. this will require progress in the purification of the receptor itse ... | 1989 | 2653194 |
| tropical infections after renal transplantation. | 1989 | 2652678 | |
| [hepatic mesenchymal hamartoma]. | a case is presented of a 10-year-old female twin with a cystic liver mass that debuted as a painless epigastric mass. the lesion was excised by hepatectomy of segments ii and iii, confirming in the review of the cavity the presence of a common mesentery with cecocolonic malposition. the postoperative course was normal and clinical and echographic study of her twin sister disclosed no anomalies. the anatomopathologic study of the lesion revealed a tumor of difficult filiation that presented featu ... | 2009 | 2652212 |
| [resistance to infection. physiology and pathology of the immune system]. | the contribution of observations in congenital deficiency disorders to our understanding of normal mechanisms can hardly be overestimated, as may in particular be seen in the complex field of mechanisms aiming at maintaining the individual integrity. after a brief summary of the natural lines of defense we demonstrate a few cases with typical deficiencies, i.e. of the integuments (ciliary dyskinesia syndrome), of the phagocytes (chronic granulomatous disease = cgd), of specific immune reactions ... | 1989 | 2652037 |