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bioterrorism on the home front: a new challenge for american medicine. 200111722275
death due to bioterrorism-related inhalational anthrax: report of 2 patients.on october 9, 2001, a letter containing anthrax spores was mailed from new jersey to washington, dc. the letter was processed at a major postal facility in washington, dc, and opened in the senate's hart office building on october 15. between october 19 and october 26, there were 5 cases of inhalational anthrax among postal workers who were employed at that major facility or who handled bulk mail originating from that facility. the cases of 2 postal workers who died of inhalational anthrax are r ...200111722269
clinical presentation of inhalational anthrax following bioterrorism exposure: report of 2 surviving patients.the use of anthrax as a weapon of biological terrorism has moved from theory to reality in recent weeks. following processing of a letter containing anthrax spores that had been mailed to a us senator, 5 cases of inhalational anthrax have occurred among postal workers employed at a major postal facility in washington, dc. this report details the clinical presentation, diagnostic workup, and initial therapy of 2 of these patients. the clinical course is in some ways different from what has been d ...200111722268
anthrax: a motor protein determines anthrax susceptibility.a new study has found that polymorphisms in the host gene kif1c, which encodes a kinesin-like motor protein, determine whether mouse macrophages are resistant or sensitive to anthrax lethal toxin. these findings may lead the way to discovering how both germ and host factors might contribute to a lethal infection.200111719234
the loss of innocence. 200111718352
bioterrorism in the united states: take it seriously. 200111718117
hyping bioterrorism obscures real concerns. 200111718116
crystallization and preliminary x-ray study of the edema factor exotoxin adenylyl cyclase domain from bacillus anthracis in the presence of its activator, calmodulin.edema factor from bacillus anthracis is a 92 kda secreted adenylyl cyclase exotoxin and is activated by the host-resident protein calmodulin. calmodulin is a ubiquitous intracellular calcium sensor in eukaryotes and activates edema factor nearly 1000-fold upon binding. while calmodulin has many known effectors, including kinases, phosphodiesterases, motor proteins, channels and type 1 adenylyl cyclases, no structures of calmodulin in complex with a functional enzyme have been solved. the crystal ...200111717504
anthrax as a cancer drug? 200111717324
anthrax. the mystery deepens. 200111715914
who should get flu shots? 200111715913
[this concerns your patients. how does one recognize anthrax? (interview by dr. roland knauer)]. 200111715871
bugs, bared. genome sequences of killer microbes reveal the arsenals of infection. 200111715870
counting deadly spores. 200111715866
clueless in manhattan. 200111715865
cdc has anthrax, smallpox vaccination guidelines available. 200111715817
life on alert. nation remains jittery as threats keep coming. 200111715791
how little we really know. 200111715747
sketchy isn't best. hospitals fault feds for poor anthrax guidance. 200111715739
mapping the anthrax protective antigen binding site on the lethal and edema factors.entry of anthrax edema factor (ef) and lethal factor (lf) into the cytosol of eukaryotic cells depends on their ability to translocate across the endosomal membrane in the presence of anthrax protective antigen (pa). here we report attributes of the n-terminal domains of ef and lf (ef(n) and lf(n), respectively) that are critical for their initial interaction with pa. we found that deletion of the first 36 residues of lf(n) had no effect on its binding to pa or its ability to be translocated. to ...200211714723
anthrax battle continues; office of public health preparedness emerges. 200111713771
bioterrorism. labs tighten security, regardless of need. 200111711648
scientists against biological weapons. 200111711640
see this goop? it kills anthrax. 200111710273
what you should know. confusion about anthrax and what to do about it abounds; here are answers, straight and up to date. 200111710270
into the zone of the unknown. it's been the blind leading the blind through the maze of anthrax. 200111710269
anthrax nation. 200111710268
'i need scientists!'. 200111710160
protecting america. the top 10 priorities. 200111710159
the hunt for the anthrax killers. 200111710155
interim recommendations for protecting workers from exposure to bacillus anthracis in work sites in which mail is handled or processed.cdc has developed interim recommendations to assist personnel responsible for occupational health and safety in developing a comprehensive program to reduce potential cutaneous or inhalational exposures to bacillus anthracis spores among workers in work sites in which mail is handled or processed. such work sites include post offices, mail distribution/handling centers, bulk mail centers, air mail facilities, priority mail processing centers, public and private mail rooms, and other settings in ...200111708595
updated recommendations for antimicrobial prophylaxis among asymptomatic pregnant women after exposure to bacillus anthracis.the antimicrobial of choice for initial prophylactic therapy among asymptomatic pregnant women exposed to bacillus anthracis is ciprofloxacin, 500 mg twice a day for 60 days. in instances in which the specific b. anthracis strain has been shown to be penicillin-sensitive, prophylactic therapy with amoxicillin, 500 mg three times a day for 60 days, may be considered. isolates of b. anthracis implicated in the current bioterrorist attacks are susceptible to penicillin in laboratory tests, but may ...200111708594
update: investigation of bioterrorism-related anthrax and interim guidelines for clinical evaluation of persons with possible anthrax.since october 3, 2001, cdc and state and local public health authorities have been investigating cases of bioterrorism-related anthrax. this report updates findings as of october 31, and includes interim guidelines for the clinical evaluation of persons with possible anthrax. a total of 21 cases (16 confirmed and five suspected) of bioterrorism-related anthrax have been reported among persons who worked in the district of columbia, florida, new jersey, and new york city (figure 1). until the sou ...200111708591
pediatric implications in bioterrorism part ii: postexposure diagnosis and treatment.bioterrorism is an old tactic used in warfare. the use of fatal diseases or man-made poisons to subdue others has not been limited to wartime. trauma personnel should be aware of commonly used agents, the signs and symptoms of their exposure, and recommended treatment. children can be victims of terrorists' acts and need special attention because of their unique response to exposure, varying dosages of medications, and lack of active immunity.200111707769
anthrax in usa--attacks "deadly but treatable". 200111705575
us anthrax scares prompt action on bioterrorism. 200111705502
letter in pakistan tests positive for anthrax spores. 200111705501
risk of deliberately induced anthrax outbreak. 200111705480
recognition and management of anthrax--an update. 200111704686
index case of fatal inhalational anthrax due to bioterrorism in the united states. 200111704685
images in clinical medicine. cutaneous anthrax infection. 200111704684
cutaneous bacillus anthracis infection. 200111704683
experts doubts us is ready for biowarfare attack. 200111702725
anthrax. 200111702421
chemistry. nota bene: know thine enemy. 200111701920
anthrax. biodefense hampered by inadequate tests. 200111701907
counterterrorism. u.s. enlists researchers as fight widens against bioterrorism. 200111701894
crystal structure of the anthrax lethal factor.lethal factor (lf) is a protein (relative molecular mass 90,000) that is critical in the pathogenesis of anthrax. it is a highly specific protease that cleaves members of the mitogen-activated protein kinase kinase (mapkk) family near to their amino termini, leading to the inhibition of one or more signalling pathways. here we describe the crystal structure of lf and its complex with the n terminus of mapkk-2. lf comprises four domains: domain i binds the membrane-translocating component of anth ...200111700563
identification of the cellular receptor for anthrax toxin.the tripartite toxin secreted by bacillus anthracis, the causative agent of anthrax, helps the bacterium evade the immune system and can kill the host during a systemic infection. two components of the toxin enzymatically modify substrates within the cytosol of mammalian cells: oedema factor (of) is an adenylate cyclase that impairs host defences through a variety of mechanisms including inhibiting phagocytosis; lethal factor (lf) is a zinc-dependent protease that cleaves mitogen-activated prote ...200111700562
tackling anthrax. 200111700539
universities address mail security as anthrax fears rise. 200111700511
update: investigation of bioterrorism-related anthrax and interim guidelines for exposure management and antimicrobial therapy, october 2001.since october 3, 2001, cdc and state and local public health authorities have been investigating cases of bioterrorism-related anthrax. this report updates previous findings, provides new information on case investigations in two additional areas, presents the susceptibility patterns of bacillus anthracis isolates, and provides interim recommendations for managing potential threats and exposures and for treating anthrax.200111699843
attempts to stem anthrax fears stumble. 200111699540
war on terror. epidemic threats. 200111699429
war on terror: biochem. tracking anthrax. 200111699428
confusion in spades. the anthrax scares reveal a public-health system in disarray. 200111699231
a no-show vaccine--for a mere $126 million. deal? 200111699229
tools of mass distraction. 200111699228
perspectives. terrorism event no time to be learning on the job. 200111699157
be a patriot. don't hoard cipro! 200111699135
a dose of reality for the health watchdogs. 200111699134
homeland insecurity. 200111699131
anthrax, united states of america (update). 200111697083
bayer cuts price of ciprofloxacin after bush threatens to buy generics. 200111691754
toll of anthrax cases reaches 15. 200111691753
how anthrax gets a grip on cells. 200111691752
prophylactic treatment of anthrax with antibiotics. 200111691746
science marshalled to cut bioterror confusion. 200111689904
crackdown on hazardous agents raises concern for bona fide labs. 200111689899
bioterrorism threat becomes reality. 200111689863
a battle cry for biomedicine. 200111689860
us expands anti-bioterrorist measures. 200111689831
post-exposure anthrax prophylaxis. 200111689760
recognition of illness associated with the intentional release of a biologic agent.on september 11, 2001, following the terrorist incidents in new york city and washington, d.c., cdc recommended heightened surveillance for any unusual disease occurrence or increased numbers of illnesses that might be associated with the terrorist attacks. subsequently, cases of anthrax in florida and new york city have demonstrated the risks associated with intentional release of biologic agents. this report provides guidance for health-care providers and public health personnel about recogniz ...200111686473
update: investigation of anthrax associated with intentional exposure and interim public health guidelines, october 2001.on october 4, 2001, cdc and state and local public health authorities reported a case of inhalational anthrax in florida. additional cases of anthrax subsequently have been reported from florida and new york city. this report updates the findings of these case investigations, which indicate that infections were caused by the intentional release of bacillus anthracis. this report also includes interim guidelines for postexposure prophylaxis for prevention of inhalational anthrax and other informa ...200111686472
bioterrorism: safeguarding the public's health. 200111684202
protecting yourself. 200111682958
a new state of fear. 200111682956
anthrax. deadly delivery. 200111682912
shadow of fear. 200111682911
danger: handle with care. 200111682910
war on terror. a run on antibiotics. 200111682909
war on terror. anxious about anthrax. 200111682908
bioterrorism. researchers question obsession with cipro. 200111679638
anthrax blamed as two postal workers die in united states. 200111679374
preparedness and response to bioterrorism.as we enter the 21st century the threats of biological warfare and bioterrorism (so called asymmetric threats) appear to be more real than ever before. historical evidence suggests that biological weapons have been used, with varying degrees of success, for many centuries. despite the international agreements to ban such weapons, namely the 1925 geneva protocol and the 1975 biological and toxin weapons convention, there is no effective international mechanism for challenging either the developme ...200111676515
human anthrax in india: urgent need for effective prevention.anthrax is a zoonotic illness caused by bacillus anthracis. sporadic cases continue to be reported from many parts of the world. from india, both sporadic cases and outbreaks are being reported regularly. the union territory of pondicherry (a former french colony) lies on the coast of bay of bengal, where the incidence of anthrax is on the rise with 28 cases being detected in the year 1999 and 2000 alone. so far, about 34 human cases have been encountered in this region. recently, an increase in ...200011668934
uk doctors given guidance on dealing with anthrax. 200111668123
us fear of bioterrorism spreads as anthrax cases increase. 200111668122
appropriate responses to bioterrorist threats. 200111668117
airman discharged for refusal to take anthrax vaccine as rebellion grows. 199911647631
bioterrorism. vaccines for biodefense: a system in distress. 200111641476
bioterrorism. this time it was real: knowledge of anthrax put to the test. 200111641469
the 1919 anthrax outbreak in louisiana. 200011640246
the control of woolsorter's disease. 197511630665
[not available]. 197811627960
[not available]. 197311626873
[zoeros pasha's report presented to the sultinate on his return from paris].the ottoman empire dispatched a committee consisting of zoeros pasha, the president, dr. hüseyin remzi and veterinarian hüseyin hüsnü, who were members sent to learn how the method of the vaccination of rabies was practiced in paris in 1886. zoeros pasha relates their studies in paris, as well as his idea on the novelties he observed there and comments on the advantages of them in case of application in the empire, in his report dated december 29th of 1886, prepared on his return from paris. zoe ...199511625087
diseases revisited, or anthrax and bovine spongiform encephalopathy. 199211623149
[anthrax: a malady of animals and of man which hides in the earth].anthrax is an infectious disease of herbivores, especially sheep and cattle, but also of horses, of pigs, of dogs, of wild animals and of humans. bacillus anthracis causes the disease. this bacterium needs plenty of oxygen to procreate and to produce resistant spores, which remains viable in the soil during 3.5 years, at times during 15-20 years. the author tries to follow step by step the evolution of the ideas concerning the origin and the pathology as well as of the veterinarians measures ag ...199711619781
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