Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| supply chain vulnerable in many ways. | the specter of terrorism has reached the materials management department, now that a supply room worker in a new york hospital has died from anthrax. at the same time, the tragedy of the sept. 11 attacks has led hospitals and their vendors to realize that "partnership" is not just a trendy word for business association anymore; it is a strategy for survival. | 2001 | 11775270 |
| bioterrorism. | 2001 | 11774753 | |
| biological agents: weapons of warfare and bioterrorism. | the use of microorganisms as agents of biological warfare is considered inevitable for several reasons, including ease of production and dispersion, delayed onset, ability to cause high rates of morbidity and mortality, and difficulty in diagnosis. biological agents that have been identified as posing the greatest threat are variola major (smallpox), bacillus anthracis (anthrax), yersinia pestis (plague), clostridium botulinum toxin (botulism), francisella tularensis (tularaemia), filoviruses (e ... | 2001 | 11774197 |
| science and the fight against bioterrorism. | 2002 | 11772930 | |
| september 11: the response and role of public health. | 2002 | 11772747 | |
| optimization of the cell wall microenvironment allows increased production of recombinant bacillus anthracis protective antigen from b. subtilis. | the stability of heterologous proteins secreted by gram-positive bacteria is greatly influenced by the microenvironment on the trans side of the cytoplasmic membrane, and secreted heterologous proteins are susceptible to rapid degradation by host cell proteases. in bacillus subtilis, degradation occurs either as the proteins emerge from the presecretory translocase and prior to folding into their native conformation or after the native conformation has been reached. the former process generally ... | 2002 | 11772631 |
| optic neuritis after anthrax vaccination. | to report the occurrence of optic neuritis after anthrax vaccination in two patients. | 2002 | 11772587 |
| is anthrax the next lyme disease? | 2001 | 11771484 | |
| systemic toxins. signs, symptoms & management of patients in septic shock. | 2001 | 11771375 | |
| use of onsite technologies for rapidly assessing environmental bacillus anthracis contamination on surfaces in buildings. | environmental sampling to ascertain the presence of bacillus anthracis spores in buildings is an important tool for assessing risk for exposure. similar to diagnostic testing, culture with positive identification of b. anthracis (cdc culture method) is the confirmatory test. laboratory-based polymerase chain reaction (pcr) methods for detecting genetic material of b. anthracis can be used in preliminary assessments and as adjuncts to microbiologic methods. although these tests are consistent wit ... | 2001 | 11770505 |
| update: investigation of bioterrorism-related anthrax--connecticut, 2001. | cdc and state and local health departments continue investigating cases of bioterrorism-related anthrax. this report revises the number of suspected cases and updates the investigation of a 94-year-old connecticut (ct) resident who died from inhalational anthrax. | 2001 | 11770501 |
| [female patient with cutaneous anthrax in belgium]. | a 23-year-old turkish woman was admitted with an infection of the left thumb. the clinical picture was typical for cutaneous anthrax. microbiological tests confirmed the diagnosis 'infection by bacillus anthracis'. she recovered when treated with penicillin, although later tests revealed that the bacteria were resistant to this antibiotic. the patient became infected in belgium as a result of wounding herself on the teeth of an illegally slaughtered sheep, which had possibly become infected in t ... | 2001 | 11770267 |
| [anthrax due to deliberate infection]. | anthrax is a zoonosis which is particularly prevalent in cattle, goats and sheep and is caused by bacillus anthracis, a gram-positive spore forming aerobic microorganism. the endospores can survive outside of the body for many decades. the natural form of anthrax has a cutaneous, pulmonary and intestinal form. the pulmonary form can be rapidly fatal but is difficult to recognise due to an initially non-specific, flu-like clinical picture. as a result of spores being inhaled, a mediastinal lympha ... | 2001 | 11770263 |
| [infectious diseases as a weapon: vigilance is needed]. | the deliberate inclusion of bacillus anthracis spores in mail has led to several cases of anthrax in the usa of which to date four have been fatal. shortly before these incidents, the health council of the netherlands had issued an advisory document which stressed the need for a well-established infrastructure and rigorous protocols so that an immediate and adequate response to cases of bioterrorism could be ensured. physicians are expected to know the characteristics of the relevant diseases an ... | 2001 | 11770262 |
| are you ready for anthrax, or worse? you must revamp your bioterrorism plan. | a study has shown that eds are unprepared to handle mass casualties of bioterrorism, and plans must be revamped. alternate care and triage areas must be selected in advance and may include parking lots and hallways between buildings. care for contaminated patients in areas that can be abandoned, so regular patient care areas are not disrupted. have a system in place to decontaminate patients before they enter the ed. | 2001 | 11769134 |
| anthrax, bioterrorism fears stimulate immune, other research. | 2001 | 11768882 | |
| the anthrax detectives. | 2001 | 11767897 | |
| old biological threats. | 2001 | 11766557 | |
| anthrax. | 2001 | 11766556 | |
| pasteur returns. | 2001 | 11766555 | |
| bioterrorism: defending the public's health in a time of national crisis. | 2001 | 11765711 | |
| [anthrax and carbuncle]. | anthrax is a name given in french language to two distinct infectious diseases. one corresponds to carbuncle which is a collection of boils. the other one corresponds to the english term anthrax. this condition has a clinical presentation and an outcome that vary according to the inoculation site being cutaneous, pulmonary or digestive, and to the bacterial and toxin spread in the body. | 2001 | 11765578 |
| cashing in on fear. | 2001 | 11765372 | |
| bioterrorism: what practicing physicians can do. | 2001 | 11765124 | |
| bioterrorism: an unintended boost to public health? | 2001 | 11765120 | |
| biological and chemical terrorism: recognition and management. | primary care physicians will be on the front line in detecting and managing any future terrorist attacks that use chemical or biological agents. this article reviews how to recognize and treat disease caused by exposure to nerve agents, blistering agents, hydrogen cyanide, ricin, anthrax, smallpox, plague, and botulinum toxin. | 2001 | 11765118 |
| september 11. | 2001 | 11765105 | |
| cdc updates interim guidelines for anthrax exposure management and antimicrobial therapy. | 2001 | 11764868 | |
| from the centers for disease control and prevention. recommendations for antimicrobial prophylaxis for children and breastfeeding mothers and treatment of children with anthrax. | 2001 | 11763855 | |
| from the centers for disease control and prevention. investigation of bioterrorism-related anthrax, 2001. | 2001 | 11763854 | |
| jama patient page. anthrax. | 2001 | 11763849 | |
| from the centers for disease control and prevention. interim guidelines for investigation of and response to bacillus anthracis exposures. | 2001 | 11763848 | |
| from the centers for disease control and prevention. considerations for distinguishing influenza-like illness from inhalational anthrax. | 2001 | 11763847 | |
| from the centers for disease control and prevention. investigation of bioterrorism-related anthrax and adverse events from antimicrobial prophylaxis. | 2001 | 11763846 | |
| pharmacy preparedness for incidents involving weapons of mass destruction. | recent worldwide terrorist acts and hoaxes have heightened awareness that incidents involving weapons of mass destruction (wmd) may occur in the united states. with federal funding assistance, local domestic preparedness programs have been initiated to train and equip emergency services and emergency department personnel in the management of large numbers of casualties exposed to nuclear, biological, or chemical (nbc) agents. hospital pharmacies will be required to provide antidotes, antibiotics ... | 2001 | 11763806 |
| ciprofloxacin frenzy. | 2001 | 11763803 | |
| special health care team screens postal workers for anthrax. | 2001 | 11763796 | |
| cdc broadcast aims to improve clinicians' grasp of anthrax issues. | 2001 | 11763795 | |
| clinicians must be voice of reason, reassurance now that bioterrorism battle has been joined. | 2001 | 11763593 | |
| anthrax: walking the fine line between precaution and panic. | 2001 | 11762587 | |
| how much is enough? aha, lawmakers debate federal funding for bioterrorism preparation. | the anthrax outbreak was just the beginning. recently the nation's hospitals got their first taste of dealing with a bioterrorism attack. and as fears of different terrorist onslaughts escalate, healthcare providers struggle to answer questions they never faced before--and to anticipate new ones. | 2001 | 11761733 |
| wv department of health and human services. information for physicians: anthrax. | 2001 | 11761656 | |
| overlooked in cipro hype: other anti-anthrax meds. | 2001 | 11761591 | |
| bioterrorism. implications for the occupational and environmental health nurse. | 1. bioterrorism is the intentional release of a biological agent--bacterial, viral, or genetically altered--to instill fear or create chaos, massive casualities, illness, and death in humans, animals, or plants. 2. the threat of bioterrorism is real. although every community is vulnerable, terrorists seek densely populated, highly visible targets. 3. occupational and environmental health nurses must to be able to recognize and report signs and symptoms of an early bioweapons outbreak in their wo ... | 2001 | 11760706 |
| [anthrax transmission from patient to patient?]. | 2001 | 11760547 | |
| [anthrax. description of symptoms, findings, diagnostics and treatment of infection]. | 2001 | 11760546 | |
| smallpox and anthrax vaccine information. | 2001 | 11760366 | |
| from the centers for disease control and prevention. interim recommendations for protecting workers from exposure to bacillus anthracis in work sites in which mail is handled or processed. | 2001 | 11759669 | |
| from the centers for disease control and prevention. updated recommendations for antimicrobial prophylaxis among asymptomatic pregnant women after exposure to bacillus anthracis. | 2001 | 11759668 | |
| from the centers for disease control and prevention. investigation of bioterrorism-related anthrax and interim guidelines for clinical evaluation of persons with possible anthrax. | 2001 | 11759667 | |
| evaluating the threat. | 2001 | 11759581 | |
| anthrax vaccine: what you need to know. | 2001 | 11759436 | |
| anthrax: a primer for practitioners. | 2001 | 11759435 | |
| cdc issues guidelines on illnesses associated with intentional release of biologic agents. | 2001 | 11759081 | |
| from the centers for disease control and prevention. update: investigation of bioterrorism-related anthrax and interim guidelines for exposure management and antimicrobial therapy, october 2001. | 2001 | 11757528 | |
| from the centers for disease control and prevention. recognition of illness associated with the intentional release of a biologic agent. | 2001 | 11757497 | |
| from the centers for disease control and prevention. investigation of anthrax associated with intentional exposure and interim public health guidelines, october 2001. | 2001 | 11757496 | |
| bioterrorism--biotechnology to the rescue? | 2002 | 11753354 | |
| breakthrough of the year. the year of living dangerously. | 2001 | 11752537 | |
| betawrap: successful prediction of parallel beta -helices from primary sequence reveals an association with many microbial pathogens. | the amino acid sequence rules that specify beta-sheet structure in proteins remain obscure. a subclass of beta-sheet proteins, parallel beta-helices, represent a processive folding of the chain into an elongated topologically simpler fold than globular beta-sheets. in this paper, we present a computational approach that predicts the right-handed parallel beta-helix supersecondary structural motif in primary amino acid sequences by using beta-strand interactions learned from non-beta-helix struct ... | 2001 | 11752429 |
| control of anthrax toxin gene expression by the transition state regulator abrb. | bacillus anthracis produces the anthrax toxin proteins protective antigen (pa), lethal factor (lf), and edema factor (ef) in a growth phase-dependent manner when cultured in liquid medium. expression of the toxin genes paga, lef, and cya peaks in late log phase, and steady-state levels of the toxin proteins are highest during the transition into stationary phase. here we show that an apparent transition state regulator negatively regulates toxin gene expression. we identified two orthologues of ... | 2002 | 11751813 |
| bioterrorism. lessons learned so far. | 2001 | 11751087 | |
| antimicrobial sensitivity in enterobacteria from aids patients, zambia. | mycoplasma contamination of the licensed anthrax vaccine administered to military personnel has been suggested as a possible cause of persian gulf illness. vaccine samples tested by nonmilitary laboratories were negative for viable mycoplasma and mycoplasma dna and did not support its survival. mycoplasma contamination of anthrax vaccine should not be considered a possible cause of illness. | 2002 | 11749759 |
| bioterrorism pressure on research agendas. | 2001 | 11747829 | |
| bioterrorism-related inhalational anthrax: the first 10 cases reported in the united states. | from october 4 to november 2, 2001, the first 10 confirmed cases of inhalational anthrax caused by intentional release of bacillus anthracis were identified in the united states. epidemiologic investigation indicated that the outbreak, in the district of columbia, florida, new jersey, and new york, resulted from intentional delivery of b. anthracis spores through mailed letters or packages. we describe the clinical presentation and course of these cases of bioterrorism-related inhalational anthr ... | 2001 | 11747719 |
| detection of specific bacillus anthracis spore biomarkers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tofms) was applied for the characterization of bacillus anthracis spore biomarkers. b. anthracis spores were extracted under a simple procedure, followed by linear mode analysis, using sinapinic acid as the matrix. several markers with a mass range of 4-7 kda were detected in three b. anthracis strains: vollum, sterne and v770-np1-r. similar spectra were also obtained for spore extracts of two members ... | 2001 | 11746875 |
| the department of defense birth defects registry: overview of a new surveillance system. | the u.s. department of defense (dod) is challenged with monitoring and protecting the health and wellbeing of its service members. the growing number of women on active duty and the diverse hazardous exposures associated with military service make reproductive health issues a special concern of dod. to address this concern, the dod birth defects registry was established at the dod center for deployment health research located at the naval health research center, san diego, california. | 2001 | 11745841 |
| responding to bioterrorism. | 2001 | 11743010 | |
| plasmid-encoded autolysin in bacillus anthracis: modular structure and catalytic properties. | a bacillus anthracis virulence plasmid-encoded peptidoglycan hydrolase (amia) with sequence similarity to n-acetylmuramoyl-l-alanine amidases hydrolyzes peptidoglycan independently of cell wall binding. residues h341, e355, h415, and e486 are absolutely required for catalysis. many amia paralogs are fused to different sorting signals, suggesting that these modular proteins result from domain shuffling. | 2002 | 11741877 |
| bacillus anthracis pxo1 plasmid sequence conservation among closely related bacterial species. | the complete sequencing and annotation of the 181.7-kb bacillus anthracis virulence plasmid pxo1 predicted 143 genes but could only assign putative functions to 45. hybridization assays, pcr amplification, and dna sequencing were used to determine whether pxo1 open reading frame (orf) sequences were present in other bacilli and more distantly related bacterial genera. eighteen bacillus species isolates and four other bacterial species were tested for the presence of 106 pxo1 orfs. three orfs wer ... | 2002 | 11741853 |
| anthrax evidence implies us culprit. | 2001 | 11740513 | |
| edwin klebs's grundversuche. | in 1876, discussions of the role of microorganisms in disease causation focused on anthrax and wound infections, and even in respect to these diseases there was controversy. in a series of papers on the pathologicality of bacteria, edwin klebs identified four "grundversuche" (fundamental tests) that provided a basis for his own research strategy. the grundversuche can be read as the following hypotheses: first, all bacteria are pathological; second, bacteria never occur spontaneously; third, eve ... | 2001 | 11740130 |
| vaccines, biological warfare, and bioterrorism. | this article presents a brief history of the use of biological agents in warfare and bioterrorism. bacillus anthracis, smallpox virus, and yersinia pestis, historically have been and currently are considered the most likely candidates for potential use under these circumstances. this article discusses the clinical syndromes these agents cause and the role of vaccines in protection against them. | 2001 | 11739031 |
| anthrax vaccine: short-term safety experience in humans. | bacillus anthracis is the major terrorist and biological warfare agent of concern to civilian and military medical planners. the licensed anthrax vaccine, adsorbed (ava) is believed to be an effective prophylactic medical countermeasure against this threat. our objective in this report was to expand the safety database for this vaccine by assessing data on self-reported, short-term safety of ava during more than 25 years of use, measured by local and systemic adverse events temporally associated ... | 2001 | 11738765 |
| induction of hepatitis c virus-specific cytotoxic t lymphocytes in mice by immunization with dendritic cells treated with an anthrax toxin fusion protein. | as a novel and safe vaccine strategy, the anthrax toxin-mediated antigen delivery system composed of lethal factor (lf) fusion protein and protective antigen (pa) has been studied to prime hepatitis c virus (hcv) core-specific cytotoxic t lymphocytes (ctls) in vivo. the core epitope fused to lf (lf-core) together with pa induces a negligible core-specific ctl response in mice, whereas core-specific ctl are effectively primed in mice by injecting dendritic cells (dcs) treated in vitro with lf-cor ... | 2001 | 11738742 |
| in vitro resistance of bacillus anthracis sterne to doxycycline, macrolides and quinolones. | bacillus anthracis is a potential biological warfare agent. its ability to develop resistance to antimicrobial agents currently recommended for the treatment of anthrax infection is a major concern. b. anthracis sterne was grown from a live veterinary vaccine and used it to test for the development of resistance after 21 sequential subcultures in sub-inhibitory concentrations of doxycycline and three quinolones (ciprofloxacin, alatrofloxacin and gatifloxacin) and 15 sequential subcultures in sub ... | 2001 | 11738344 |
| [bacillus anthracis and bioterrorism]. | 2001 | 11738001 | |
| winter, plague and pestilence. | 2001 | 11737937 | |
| cutaneous anthrax: still a reality in india. | 2001 | 11737702 | |
| fate of germinated bacillus anthracis spores in primary murine macrophages. | we investigated the fate of germinated bacillus anthracis spores after their germination in swiss murine peritoneal macrophages and in the cell line raw264.7. we found that the lethal toxin and the oedema toxin are germ-associated factors that are essential for the survival of the vegetative form in host cells. we also found that px02 is not involved in this complex pathogenic process. by transmission electron microscopy, we showed the tight interaction between the exosporium of the spore and th ... | 2001 | 11737637 |
| us anti-bioterror efforts swiftly expanding. | 2001 | 11731763 | |
| anthrax. a 'sure killer' yields to medicine. | 2001 | 11729281 | |
| a second anthrax genome project. | 2001 | 11729280 | |
| anthrax. can lab sleuths clinch the case? | 2001 | 11729279 | |
| taking anthrax's genetic fingerprints. | 2001 | 11729278 | |
| early and aggressive treatment saves us anthrax victims. | 2001 | 11728555 | |
| bleach, gas, or foam? | 2001 | 11727474 | |
| 'we're all working together.' new york-area hospitals redouble efforts in face of anthrax death. | the death of a new york hospital worker from inhalation anthrax last week put new strains on an overburdened public health system. the fact that no source of the bacteria could be found only added to the difficulties. hospitals along the east coast battled clinical, logistical and financial problems from the outbreak. | 2001 | 11727463 |
| bioterrorism: a clear and present danger. | 2001 | 11726956 | |
| rapid anthrax test developed. | 2001 | 11726951 | |
| bioterrorism watch. clinicians must be voice of reason, reassurance now that bioterrorism battle has been joined. | 2001 | 11725496 | |
| molecular investigation of the aum shinrikyo anthrax release in kameido, japan. | in 1993, the aum shinrikyo cult aerosolized bacillus anthracis spores over kameido, japan. spore samples were obtained from the release site, cultured, and characterized by molecular genetic typing. the isolates were consistent with strain sterne 34f2, which is used in japan for animal prophylaxis against anthrax. | 2001 | 11724885 |
| update: interim recommendations for antimicrobial prophylaxis for children and breastfeeding mothers and treatment of children with anthrax. | ciprofloxacin or doxycycline is recommended for antimicrobial prophylaxis and treatment of adults and children with bacillus anthracis infection associated with the recent bioterrorist attacks in the united states. amoxicillin is an option for antimicrobial prophylaxis for children and pregnant women and to complete treatment of cutaneous disease when b. anthracis is susceptible to penicillin, as is the case in the recent attacks. use of ciprofloxacin or doxycycline might be associated with adve ... | 2001 | 11724160 |
| update: investigation of bioterrorism-related anthrax, 2001. | this report updates the investigation of bioterrorism-related anthrax and the provision of antimicrobial prophylaxis to exposed persons and highlights cdc assistance to other countries investigating cases of bioterrorism-related anthrax. since november 7, 2001, cdc and state and local public health agencies have identified no new cases of bioterrorism-related anthrax. as of november 14, a total of 22 cases of anthrax has met the cdc case definition; 10 were confirmed inhalational anthrax, and 12 ... | 2001 | 11724158 |
| interim guidelines for investigation of and response to bacillus anthracis exposures. | environmental sampling. environmental testing to detect b. anthracis on surfaces or in the air can be used to investigate known or suspected exposure events. the highest priority of an investigation is to evaluate the risk for exposure to aerosolized b. anthracis spores. persons collecting and testing samples should 1) obtain adequate samples, 2) avoid cross-contamination during processing, and 3) ensure proficient laboratory testing and interpretation of test results. a positive laboratory test ... | 2001 | 11724154 |
| considerations for distinguishing influenza-like illness from inhalational anthrax. | cdc has issued guidelines on the evaluation of persons with a history of exposure to bacillus anthracis spores or who have an occupational or environmental risk for anthrax exposure. this notice describes the clinical evaluation of persons who are not known to be at increased risk for anthrax but who have symptoms of influenza-like illness (ili). clinicians evaluating persons with ili should consider a combination of epidemiologic, clinical, and, if indicated, laboratory and radiographic test re ... | 2001 | 11724153 |
| update: investigation of bioterrorism-related anthrax and adverse events from antimicrobial prophylaxis. | cdc and state and local public health authorities continue to investigate cases of bioterrorism-related anthrax. as of november 7, a total of 22 cases of anthrax have been identified according to the cdc surveillance case definition; 10 were confirmed inhalational anthrax cases and 12 cases (seven confirmed and five suspected) were cutaneous anthrax (table 1). the majority of cases have occurred in persons working at postal facilities in new jersey (nj) and the district of columbia (dc) in which ... | 2001 | 11724150 |
| something she called a fever: michelet, derrida, and dust. | 2001 | 11724069 | |
| [bacillus anthracis, an old friend in a new appearance?]. | 2001 | 11723811 | |
| optimization of an oligonucleotide microchip for microbial identification studies: a non-equilibrium dissociation approach. | the utility of a high-density oligonucleotide microarray (microchip) for identifying strains of five closely related bacilli (bacillus anthracis, bacillus cereus, bacillus mycoides, bacillus medusa and bacillus subtilis) was demonstrated using an approach that compares the non-equilibrium dissociation rates ('melting curves') of all probe-target duplexes simultaneously. for this study, a hierarchical set of 30 oligonucleotide probes targeting the 16s ribosomal rna of these bacilli at multiple le ... | 2001 | 11722542 |