Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [effect of astragalus membranaceus on electrophysiological activities of acute experimental coxsackie b3 viral myocarditis in mice]. | a murine model for observing the effect of astragalus membranaceus (am) on electrophysiological activity of the right ventricular myocardium was developed in 4 week-old male balb/c mice infected with coxsackie b3 virus (cb3v). the conventional microelectrode technique and real-time microcomputer data processor system was used. the survival rate in infected-am treated mice was significantly higher and the percentage of abnormal action potential was much lower than those in control mice (p < 0.05 ... | 1994 | 7950216 |
| [clinical study of baoyuan dahuang decoction in the treatment of chronic renal failure]. | the quality of life of 56 chronic renal failure (crf) patients using two kinds of treatment has been observed. 36 of them were taken as group a with bun 21.62 +/- 5.96 mmol/l, cr 528.63 +/- 176.3 mumol/l and hb 65 +/- 13 g/l were treated with baoyuan dahuang decoction consisted of panax ginseng, astragalus membranaceus, cassia cinnamomi, glycyrrhiza uralensis and rheum palmatum. result: six symptoms were observed, that were: fatigue, lassitude in loin and legs, aversion of cold, anorexia, sexual ... | 1994 | 7950208 |
| [action of astragalus membranaceus on left ventricular function of angina pectoris]. | the action on left ventricular function of astragalus membranaceus (am), a qi-tonic, in 20 patients with angina pectoris was studied by means of doppler echocardiogram (dec). it showed that cardiac output increased from 5.09 +/- 0.21 to 5.95 +/- 0.18 l/min 2 weeks after am was administered (p < 0.01), and no improvement of left ventricular diastolic function appeared. adenosine triphosphatase activity was not inhibited by using am, which was different from that of digitalis. | 1994 | 7950192 |
| [effect of jian yan ling on serum lipids, apoprotein and lipoprotein-a]. | effect of jian yan ling (jyl, mainly consisted of succinum, pteria margaritifers and astragalus membranaceus etc.) on serum lipids was studied by double-blind method in 128 hyperlipemia patients. patients were divided randomly into two groups, the test groups (64 cases) treated with jyl, while the other 64 cases treated with placebo as control for 3 months. serum total cholesterol (tc), triglyceride (tg), tc-high density lipolipid-cholesterol (tc-hdl-c), apoproteins were observed before and afte ... | 1994 | 7950180 |
| [memory-improving effect of aqueous extract of astragalus membranaceus (fisch.) bge]. | the study shows that the aqueous extract of astragulus membranaceus (amwe) can improve the anisodine-induced impairment on memory acquisition as well as the alcohol-elicited deficit of memory retrieval (number of errors were reduced and latent period was prolonged) in step down, and can also prolong the gasping duration of mice after decapitation at doses of 50g/kg (ig) for 7 days. | 1994 | 7893391 |
| [non-surgical treatment of small cell lung cancer with chemo-radio-immunotherapy and traditional chinese medicine]. | 54 consecutive cases of small cell lung cancer (sclc) were treated with longterm short-interval combined treatment modalities of chemotherapy, radiotherapy (55-65 gy), immunotherapy, traditional chinese medicine (leaf of asiatic ginseng, root of astragalus membranaceus bge, etc) and other adjuvants. chemotherapy consisted of vincristine, cyclophosphamide, methotrexate and carmustine. a complete response of 59.2%, partial response of 38.9% and an overall response of 98.1% were achieved. according ... | 1994 | 7867442 |
| chinese medicinal herbs inhibit growth of murine renal cell carcinoma. | tumors are known to produce factors suppressing immune functions. we previously showed that a murine renal cell carcinoma (renca) suppressed macrophage function in vitro and that this suppression was abolished by co-incubation with extracts of two chinese medicinal herbs. we now report that these phytochemicals are capable of inhibiting growth of renca in vivo. balb/c mice were transplanted intraperitoneally (ip) with 1-2 x 10(5) renca cells. one day after tumor transplant, mice were randomized ... | 1994 | 7812364 |
| [clinical observation on the treatment of ischemic heart disease with astragalus membranaceus]. | 92 patients suffering from ischemic heart disease was successfully treated with astragalus membranaceus (am). the effect of the treatment was compared with that of nifedipine and tab. salviae miltiorrhizae. the clinical practice showed that the group treated with am yielded better results. after having administered the drug, the patients were markedly relieved from angina pectoris (heart stroke). meanwhile the improvement of clinical objective index such as electrocardiogram (ekg) and impedance ... | 1995 | 7787395 |
| [effects of shi-ka-ron and chinese herbs in mice treated with anti-tumor agent mitomycin c]. | the shi-ka-ron, and its constituent chinese herbs lithospermum erythrorhizon, astragalus membranaceus and ligusticum wallichii were administered with antitumor agent, mitomycin c (mmc) to icr mice, and their effects on murine macrophages and lymphocytes were studied. peritoneal macrophages were significantly inhibited both in their number and chemotactic activity by mmc treatment. splenic weight and blastogenic responsiveness to concanavalin a of spleen lymphocytes also decreased significantly i ... | 1995 | 7787389 |
| cycloartane triterpene glycosides from the hairy root cultures of astragalus membranaceus. | agroastragaloside ii, a new astragaloside was isolated from the hairy root culture of astragalus membranaceus. its structure was established as 3-o-beta-(2'-o-acetyl)-d-xylopyranosyl-6-o-beta-d-glucopyranosyl-(24s)- 3 beta,6 alpha,16 beta,24,25-pentahydroxy-9,19-cyclolanostane on the basis of spectroscopic data. three known astragalosides, astragaloside ii, isoastragaloside i and 3-o-beta-d-xylopyranosyl-cycloastragenol were also isolated. | 1994 | 7765758 |
| effects of compound injection of pyrola rotundifolia l and astragalus membranaceus bge on experimental guinea pigs' gentamicin ototoxicity. | in attempting to find drugs effective in preventing and remedying ototoxic injury caused by aminoglycoside antibiotics, we relied on the theory that the induction of ototoxic injury by aminoglycoside antibiotics is related to a decrease of cyclic adenosine monophosphate and rna content in the cochlea or a dysfunction of the kidney. we selected pyrola rotundifolia l and astragalus membranaceus bge from traditional chinese herbal medicine, made a compound injection of them, and observed the effect ... | 1995 | 7747908 |
| [intervention of lidocaine and astragalus membranaceus on ventricular late potentials]. | 16 and 22 patients with positive ventricular late potentials (lp) recorded on signal-averaged electrocardiograms (saecg) were treated with lidocaine 100 mg iv. or astragalus membranaceus 24 g iv. drip for 2 weeks respectively. as a result, the saecgs of 2 (12.5%) and 3 (13.6%) of them normalized respectively. compared with baseline, there were no significant changes in average hfqrsd, las and rms 40 after treatment of lidocaine. hfqrsd and las were shortened significantly 115.9 +/- 29.9 vs 125.1 ... | 1994 | 7719092 |
| [experimental studies on the effects of danggui buxue decoction on il-2 production of blood-deficient mice]. | danggui buxue decoction has shown the effect of significantly promoting the splenic capacity of blood-deficient mice in interleukin-2(il-2)production (p < 0.001). individual analysis of herbal formula has shown that il-2 production can be promoted in splenic lymphocytes of blood-deficient mice given angelica sinensis or astragalus membranaceus (p < 0.001). | 1994 | 7718137 |
| [effect and mechanism of astragalus membranaceus on coxsackie b3 virus rna in mice]. | using balb/c mice infected with coxsackie virus b3 (cvb3) as a model, the effect of astragalus membranaceus (am) on cvb3-rna has been observed in myocardial tissues of mice by rna-rna in situ hybridization with negative-strand rna probes leballing with 35s and quantitative imaging analysis of positive hybridization signals. the mechanism of its effect on cvb3-rna has also been investigated by induction with am and detection of beta-interferon (beta-ifn). results showed that the copy numbers of c ... | 1994 | 7703635 |
| [comparison of effect of astragalus membranaceus and huoxuefang on thromboxane, prostacyclin and adenosine cyclic monophosphate in cerebral reperfusion injury in rabbits]. | the cerebral ischemia rabbit model was made by using the occlusion of four vessels. the results showed that txb2 and camp contents in brain tissues and the latter in plasma markedly increased (p < 0.05, p < 0.01), the 6-keto-pgf1 alpha in brain tissues significantly lowered (p < 0.05) in ischemia formed 30 minutes and 45 minutes after reperfusion. after intravenous injection of astragalus membranaceus (am) extracts (3.3 g/kg), huoxuefang (hxfo and yiqi houxue fang (yqhxf) consisted of am and hxf ... | 1995 | 7647534 |
| [effects of astragalus membranaceus on left ventricular function and oxygen free radical in acute myocardial infarction patients and mechanism of its cardiotonic action]. | dynamic observations for 4 weeks were made on left ventricular function and oxygen free radical (ofr) in 43 patients first suffering from acute myocardial infarction and hospitalized in coronary care unit with an attack less than 36 hours. the results showed that the astragalus membranaceus (am) could strengthen the left ventricular function and had an effect of anti-ofr. after administration of am, the ratio of pre-ejection period/left ventricular ejection time (pep/lvet) was decreased, the sup ... | 1995 | 7647526 |
| [effect of astragalus membranaceus on t-lymphocyte subsets in patients with viral myocarditis]. | the efficacy of astragalus membranaceus (am) oral liquor combined with routine therapy and routine therapy alone on t-lymphocyte subsets of peripheral blood in viral myocarditis patients have been studied. the results showed that the t-lymphocyte subsets profile and okt4/okt8 ratio of peripheral blood were significantly lower in viral myocarditis patients than that in healthy control (p < 0.05, 0.01). routine therapy combined with am could significantly enhance okt3, okt4 and okt4/okt8 ratio in ... | 1995 | 7549379 |
| preliminary observations on the effects of the chinese medicinal herbs astragalus membranaceus and ligustrum lucidum on lymphocyte blastogenic responses. | the biological effects of extracts of two chinese medicinal herbs, astragalus membranaceus and ligustrum lucidum, on in vitro lymphocyte blastogenesis were assessed. aqueous extracts augmented the spontaneous [3h]thymidine incorporation in the mononuclear cells (mnc) of 14 normal subjects from 273.0 to 609.3 counts per minute (cpm) and 252.9 to 656.9 cpm for the two herbs, respectively. the stimulation indices were 2.4 and 3.1, respectively (p less than 0.001). they also augmented the proliferat ... | 1983 | 6644339 |
| immune restoration and/or augmentation of local graft versus host reaction by traditional chinese medicinal herbs. | the in vitro restorative effect of aqueous extracts from two traditional chinese medicinal herbs were studied in 19 cancer patients and in 15 normal healthy donors. using the local graft versus host (gvh) reaction as a test assay for t-cell function, the extract from astragalus membranaceus (10 microgram/ml) induced a restored reaction in nine of ten patients with an increase in local gvh reaction from 18.2 plus/minus 15.8 mm3 to 112.9 plus/minus 94.2 mm3 (p less than 0.01). the extract from lig ... | 1983 | 6336578 |
| [study on the biologically active constituents of astragalus membranaceus]. | 1984 | 6237798 | |
| [effect of ph on hemolytic activity and stability of astragalus membranaceus injection]. | 1984 | 6237759 | |
| [preliminary observation on the therapeutic effect of astragalus membranaceus in experimental anti-glomerular basement membrane nephritis in rabbits]. | 1983 | 6227416 | |
| [effects of astragalus membranaceus on enhancement of mouse natural killer cell activity]. | 1983 | 6197202 | |
| [on the pharmacognosy of astragalus membranaceus tish (bge)]. | 2014 | 5611766 | |
| treating amenorrhea in vital energy-deficient patients with angelica sinensis-astragalus membranaceus menstruation-regulating decoction. | 2013 | 3807414 | |
| [the effect of the chinese medical herbs astragalus membranaceus and angelica sinensis on 3 kinds of experimental nephritis]. | 1986 | 3743217 | |
| [changes in proteinuria, renal function and immunity after treatment with injections of a solution of astragalus membranaceus]. | 1987 | 3690764 | |
| [synergism of astragalus membranaceus with interferon in the treatment of cervical erosion and their antiviral activities]. | 1987 | 3319216 | |
| fractionated extract of astragalus membranaceus, a chinese medicinal herb, potentiates lak cell cytotoxicity generated by a low dose of recombinant interleukin-2. | success with ril-2 immunotherapy of human cancer appears to depend on the administration of high doses which are frequently associated with excessive toxicity. future use of ril-2 will require certain modifications based on the use of lower doses of ril-2 without significant loss of antitumor efficacy. we tested in vitro the possibility of potentiating the activity of ril-2 in terms of lak cell generation. we hypothesized that co-incubation of lak cell precursors with a chinese herbal extract (f ... | 1988 | 3264344 |
| immunotherapy with chinese medicinal herbs. ii. reversal of cyclophosphamide-induced immune suppression by administration of fractionated astragalus membranaceus in vivo. | a partially purified fraction (f3) with an estimated molecular weight of 20,000 to 25,000 derived from the traditional chinese medicinal herb astragalus membranaceus, was found to possess a potent immunorestorative activity in vitro. its capacity to aborogate the local xenogeneic graft versus host reaction (xgvhr) following injection in vivo was further studied in a newly developed animal model designed for preclinical evaluation of various biological response modifiers. f3 was injected intraven ... | 1988 | 3260961 |
| immunotherapy with chinese medicinal herbs. i. immune restoration of local xenogeneic graft-versus-host reaction in cancer patients by fractionated astragalus membranaceus in vitro. | the in vitro immunomodulatory activity of fractions derived from astragalus membranaceus, an herb commonly used in the practice of traditional chinese medicine, was first screened by studying their individual effects on mononuclear cells (mnc) derived from healthy normal donors using the local xenogeneic graft-versus-host reaction (xgvhr). sephacryl s-200 column-separated fraction 3 (mw 20,000-25,000) along with its crude extract precursor, fraction 7, and another crude extract derivative, fract ... | 1988 | 3260960 |
| [pharmacological action of astragalus membranaceus on the central nervous system in mice]. | 2010 | 2952357 | |
| [quantitative determination of astragaloside a in astragalus membranaceus]. | 1986 | 2952353 | |
| effect of astragalus membranaceus injecta on coxsackie b-2 virus infected rat beating heart cell culture. | 1987 | 2827966 | |
| [immune restoration of local xenogeneic graft-versus-host reaction in cancer patients in vitro and reversal of cyclophosphamide-induced immune suppression in the rat in vivo by fractionated astragalus membranaceus]. | through the process of fractionation, purification by gel filtration chromatography and thereafter the screening with an in vitro local xenogeneic graft-versus-host reaction (xgvhr) model, a fraction was identified as a potent immunorestorative agent and was designated "fraction 3" (f3). using the xgvhr in vitro as a model assay for t cell function again, f3 was studied on mononuclear cells (mnc) from 13 cancer patients and exhibited significant immunorestorative activity, with an increase in lo ... | 1989 | 2789109 |
| [a clinical study on the treatment of acute upper digestive tract hemorrhage with wen-she decoction]. | this paper deals with the prospective clinical study on treatment of acute upper digestive tract hemorrhage with wen-she decoction (wsd). an opened sequential controlled trial method of simple orientation quality reaction was adopted in this study. 7 cases were treated and all of them were cured. it was concluded that wsd was an excellent therapy to treat the middle or small amount hemorrhage of acute upper digestive tract. the effective rate of wsd of the stool ob (+) becoming (-) within 5 days ... | 1989 | 2766422 |
| [an experimental study on the anti-senility effects of shou xing bu zhi]. | this paper presents the anti-senility effects of shou xing bu zhi (sxbz. made of thirteen herbs: polygonum multiflorum, codonopsis silvestris, astragalus membranaceus, poria cocos, etc.) in mice. the mice were administered with the sxbz orally at dosage of 10 g/kg daily for three months. the results showed that the lipofuscin of liver and brain tissues was significantly reduced in both young (1 month old) and adult (11 months) mice. examination of lipid peroxidation of liver tissue revealed a ma ... | 1989 | 2758519 |
| [influence of astragalus membranaceus (am) polysaccharide fb on immunologic function of human periphery blood lymphocyte]. | chemotherapy and/or radiotherapy are believed to further lower the already low cellular immunologic response of cancer patients giving poorer prognosis. a number of chinese medicinal herbs known as fuzheng therapy (fzt), in which am is an active one, are being used to enhance the natural host defence function in cancer patients. among some fractions of am polysaccharide extracts, fb was the strongest. in vitro restorative effects of fb in 18 normal healthy individuals and in 9 previously untreat ... | 1989 | 2612327 |
| [effect of astragalus membranaceus on electrical activities of coxsackie b-2 virus-infected rat myocardial cells in culture]. | beating myocardial cell cultures of neonatal rats were prepared in vitro and infected with coxsackie b-2 virus. the cells were evaluated in the post-infected period for changes in beating percentage and cytopathic effect (cpe), alterations in the electrical activities by standard microelectrode techniques, and the protective effect of astragalus membranaceus (am) on coxsackie b-2 virus-infected neonatal rat myocardial cell cultures was observed. the beating percentage began to decrease in the in ... | 1989 | 2550160 |
| [influence of yang-restoring herb medicines upon metabolism of thyroid hormone in normal rats and a drug administration schedule]. | large dose of yang-restoring herb medicines. (radix codonopsis pilosulae, astragalus membranaceus, radix aconiti praeparata, epimedium brevicornum, cortex cinnamomi and herba cistanchis) may exert an unfavorable effect on normal rats, i. e. natural weight gain reduced (p less than 0.01), serum t3 decreased (p less than 0.05), rt3, trh levels raised (p less than 0.01) and tsh showed a raising tendency. lower t3 and higher rt3 levels may be the effects of yang-restoring herb medicines on the perip ... | 1989 | 2500264 |
| [advances in immuno-pharmacological studies on astragalus membranaceus]. | 1986 | 2425990 | |
| [preliminary study of traditional chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases]. | this paper reports the clinical treatment of 100 patients with minimal brain dysfunction (mbd), their age ranged from 7-14.2 years, and the average age was 10.5. patients were divided into tcm and wm group randomly. the tcm group (80 cases) were treated with the therapy of subdueing hyperactivity of the liver and invigorating the function of the spleen by using: bupleurum chinense, scutellaria baicalensis, astragalus membranaceus, codonopsis pilosula, ligustrum lucidum, lophatherum gracile and t ... | 1990 | 2397543 |
| [immunomodulatory action of the total saponin of gynostemma pentaphylla]. | the specimen of the total saponin for this experimental study was extracted from gynostemma pentaphylla growing in suining county in hunan province. weight of immune organs, content of anti-srbc hemolysin, rate of special ea-rfc formation and percentage of nk cell activity had been employed for the study as experimental indices, both the normal healthy mice and the mice with immunity impairment due to cyclophosphamide (cy) management as experimental models. the results of the study exhibited: (1 ... | 1990 | 2364471 |
| [clinical study of 96 cases with chronic hepatitis b treated with jiedu yanggan gao by a double-blind method]. | this paper reported 96 cases with chronic hepatitis b treated by a double-blind method. there were 51 cases of observation group(og) and 45 cases of control group (cg). og was treated with jiedu yanggan gao consisting of artemisia capillaris, taraxacum mongolicum, plantago seed, cephalanoplos segetum, hedyotis diffusa, flos chrysanthemi indici, smilax glabra, astragalus membranaceus, salviae miltiorrhizae, fructus polygonii orientalis, radix paeoniae alba, polygonatum sibiricum, etc.). cg was pr ... | 1990 | 2364464 |
| [f3, a fractionated extract of astragalus membranaceus, potentiates lymphokine-activated killer cell cytotoxicity generated by low-dose recombinant interleukin-2]. | success with ril-2 immunotherapy of human cancer appears to depend on the administration of high doses which are frequently associated with excessive toxicity. future use of ril-2 will require certain modifications based on the use of lower doses of ril-2 without significant loss of antitumor efficacy. the authors tested in vitro the possibility of potentiating the activity of ril-2 in terms of lak cell generation. the authors hypothesized that co-incubation of lak cell precursors with a chinese ... | 1990 | 2350835 |
| hepatoprotective effects of astraglus root. | oral administration of an ethanol extract of the root of astragalus membranaceus alleviated liver injury induced by stilbenemidine. pre-administration in mice reduced elevated sgpt levels and subacute toxicity of stilbenemidine, decreased pentobarbital-induced loss of righting reflex and protected hepatic cells from pathological changes. | 1990 | 2255205 |
| viral etiology of chronic cervicitis and its therapeutic response to a recombinant interferon. | chronic cervicitis was shown to be related to papillomavirus type 16(hpv-16), herpes simplex virus type 2 and cytomegalovirus (cmv) infections as demonstrated by dna hybridization technique and virus isolation method from samples taken from erosive and normal cervices. after one course of treatment with recombinant interferon alpha 1 (rifn-alpha 1), 93.8% of cases showed clinical improvement and 60% marked improvement. the hpv-16 and hsv detection rates dropped down significantly after rifn-alph ... | 1990 | 2173655 |
| effect of astragalus membranaceus on electric activities of cultured rat beating heart cells infected with coxsackie b-2 virus. | astragalus membranaceus (am) which has a protective effect on rat beating heart cells infected experimentally with coxsackie b-2 virus was evaluated on the basis of changes in morphologic and electric activity of the cells. rhythm, beating frequency, beating percentage, cardiac cellular damage and cytopathic effects (cpe) were monitored every 24 h after challenge; electric activities parameters were measured by conventional intracellular microelectrode technique. significant protective effects w ... | 1990 | 2164463 |
| treatment of experimental coxsackie b-3 viral myocarditis with astragalus membranaceus in mice. | a murine model system for observing the effect of astragalus membranaceus (am) on experimental myocarditis caused by coxsackie b-3 virus (cb3v) was developed in 4-week-old male balb/c mice. gross, histopathologic and ultrastructural examinations of the infected-am treated group showed that the severity and involved area of the myocardial lesions became milder and smaller than those in the infected-ns treated mice. the total lesion area, and the total lesion area/total myocardial area examined (% ... | 1990 | 2161724 |
| enhancement of the immune response in mice by astragalus membranaceus extracts. | astragalus membranaceus extracts injected into normal mice or mice immunodepressed by cyclophosphamide or radiation treatment or by aging are able to enhance the antibody response to a t-dependent antigen. optimal conditions for maximum effect have been established in normal c3h/hej and (c57b1/10 x dba/2)f1 mice. enhancement of the antibody response was associated with increase of th cell activity in normal and immunodepressed mice. the biological activity of endotoxin-free extracts is dependent ... | 2003 | 2149722 |
| [isolation and identification of chemical constituents of astragalus root]. | ten constituents have been isolated from the alcoholic extract of astragalus membranaceus var. monghlicum root. all of them were identified. among them astraisoflavanin (3s-(-)-mucronulatol-7-o-d-glucopyranoside) is a new compound. dimethyl 4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphyenyl 1-2, 2'-dicarboxylate is a known synthetic compound, but it was first isolated from natural resource astragalus root and identified by the authors. | 1990 | 2092578 |
| [the combined modulating effects of cerium nitrate with certain chinese traditional drugs on altered cell-mediated immunities in scald mice]. | altered cell-mediated immunities (cmi) is one of the important causes of increased susceptibility to infection and, high mortality of burned patients. this paper presents the experimental work on mice with scald injury to restore their altered cmi by local application of cerium nitrate (ce) or systemic administration of astragalus membranaceus (am) or lonicera japonica thunb (ljt), as well as combination use of these drugs. the proliferative response to con a and the ability of il-2 production o ... | 1990 | 2086133 |
| [effect of fu-zheng qu-xie on gastric disease infected with campylobacter pyloridis]. | chinese herbal medicine and gentamycin were used separately in the treatment of 75 cases of gastric disease by campylobacter pyloridis (cp). surveying the changes of the gastrofiberscope, pathological test, bacteriology and immunology. this study, found that in the chinese herbal medicine group clinical symptoms were obviously improving the effective rate for cp being 80% (24/30), the death rate for cp 30% (9/30), and the effective rate for patho-histological changes 50% (15/30). differences of ... | 1991 | 2065393 |
| [primary research on the clinical significance of ventricular late potentials (vlps), and the impact of mexiletine, lidocaine and astragalus membranaceus on vlps]. | the body surface signal-averaged electrocardiogram (saecg) was recorded on 316 cardiac patients, 84% (266 patients) of whom were also taken 24-hour holter ecg. vlps were detected positively in 6.1%, 25%, 25.7%, 14.3% and 5.5% of patients with angina pectoris, myocardial infarction, myocarditis, cardiomyopathy and arrhythmia of unknown origin respectively, and the patients with complex ventricular arrhythmia had more vlps positive determination definitely (p less than 0.05). the specificity of vl ... | 1977 | 1879028 |
| chinese medicinal herbs reverse macrophage suppression induced by urological tumors. | tumors are known to produce factors suppressing macrophage function. in this study we demonstrated in vitro suppression of macrophage chemiluminescent oxidative burst associated with viable cells and cell-free extracts of two urological neoplasms--murine renal cell carcinoma (renca) and murine bladder tumor (mbt). suppression was reversed by extracts of two chinese medicinal herbs, astragalus membranaceus (am) and ligustrum lucidum (ll). murine macrophage cell line j774 was incubated with either ... | 1991 | 1856958 |
| [effect of astragalus membranaceus on erythrocyte sodium content and sodium transport in the coronary heart disease]. | the purpose of this study was to investigate the effect of astragalus membranaceus (am) on erythrocyte sodium content and sodium transport in the coronary heart disease(chd). 67 cases of chd was randomly divided into treatment group (tg) and control group (cg), tg (45 cases) were treated with am intravenous 24 g/d infused into 5% glucose 250 ml, cg (22 cases) with 5% glucose 250 ml. after a curable stage of 14 days, results showed that the erythrocyte sodium content was markedly decreased and th ... | 1991 | 1667511 |
| [clinical and experimental study of the effect of kang er xin-i on viral myocarditis]. | kang er xin-i (kex-i) is a proved recipe used to treat viral myocarditis. it consists of lonicera japonica, ophiopogon japonicus, astragalus membranaceus mainly and possesses the effect of clearing away heat and toxic materials and supplementing the vital energy and nourishing. the clinical study was carried out with kex-i according to a random, paired and cross-over design. coenzyme q10 was used as a control and left ventricular function was observed. the result showed: after being treated with ... | 1991 | 1659497 |
| [the effect of astragalus polysaccharide on endotoxin-induced toxicity in mice]. | astragalus polysaccharide (aps), an active component, was isolated from the radix of astragalus membranaceus bge var. mongholicus (bge) hsiao, and the effects of aps on e. coli endotoxin-induced liver damage were investigated in mice. the results showed that when mice were pretreated with aps (30, 60, 100 mg.kg-1.d-1 x 7d, ip), the survival rate of endotoxin intoxicated mice was increased the lowering of atp levels and adenylate energy charge in mouse liver could be prevented. aps 100 mg.kg-1 co ... | 1992 | 1529714 |
| [experimental study on yiqi-huoxue therapy of liver fibrosis]. | the experimental hepatic fibrosis was treated with yiqi (reinforcing qi, yq) huoxue (activating blood circulation, hx) principle which was consisted of astragalus membranaceus, ligusticum wallichii, paeonia lactiflora, etc. after stimulation with ccl4 over four months, the wistar rat developed liver fibrosis. rats were divided into the normal control, the toxifying control, yqhx group and hx group. the experimental period lasted over four months. results: (1) mortality of animal: both toxifying ... | 1992 | 1498545 |
| astragalus membranaceus stimulates human sperm motility in vitro. | poor sperm motility is an important cause of male infertility. in an attempt to identify chinese medicinal herbs that might improve human sperm motility in vitro, we screened water extracts of 18 herbs with a trans-membrane migration method which measured the percentage of sperm that moved across the 5 micron pores of a nucleopore membrane from a semen-drug mixture into phosphate buffered saline during 2 hours incubation. astragalus membranaceus was the only herb that showed a significant stimul ... | 1992 | 1471613 |
| phytochemicals potentiate interleukin-2 generated lymphokine-activated killer cell cytotoxicity against murine renal cell carcinoma. | the success of adoptive immunotherapy using recombinant interleukin-2 (ril-2) and lymphokine-activated killer (lak) cells in several cancers has been hampered by severe toxicity associated with high doses of ril-2. methods that reduce the dosage of ril-2 without loss of clinical efficacy are needed. in this study we determined the in vitro effect of a phytochemical immune modulator, astragalus membranaceus (am), and two fractions isolated by high-performance liquid chromatography on the cytotoxi ... | 1992 | 1445669 |
| chinese medicinal herbs modulate mutagenesis, dna binding and metabolism of aflatoxin b1. | oldenlandia diffusa (od) and scutellaria barbata (sb) have been used in traditional chinese medicine for treating liver, lung and rectal tumors while astragalus membranaceus (am) and ligustrum lucidum (ll) are often used as an adjunct in cancer therapy. in this study, we determined the effects of aqueous extracts of these four herbs on aflatoxin b1 (afb1)-induced mutagenesis using salmonella typhimurium ta100 as the bacterial tester strain and rat liver 9000 x g supernatant as the activation sys ... | 1992 | 1377337 |
| mechanism of inhibition of hiv-1 infection in vitro by purified extract of prunella vulgaris. | crude extracts of four chinese herbs, arctium lappa, astragalus membranaceus, andrographis paniculata, and prunella vulgaris, were assessed in several tissue culture lines for anti-hiv activity and for cytotoxicity. one extract, obtained from p. vulgaris, was able to significantly inhibit hiv-1 replication with relatively low cytotoxicity. the active factor was purified using sequential precipitations with ethanol and n-butanol, followed by reverse-phase and gel permeation high-performance liqui ... | 1992 | 1371029 |
| [fungi isolated from diseased medicinal plants]. | one hundred and forty-four fungal isolates were obtained from diseased paeonia albiflora pall. var. trichocarpa bung., astragalus membranaceus bung., lithospermum erythrorhizon sieb. et zucc., ledebouriella seseloides wolff and bupleurum falcatum l. which were collected in the test field of tsukuba medicinal plant research station, national institute of hygienic sciences. most of them were identified into 15 genera containing 8 species. fungal species presumed to be pathogens of the host plants ... | 1992 | 1364438 |
| [effects of mixture of astragalus membranaceus, fructus ligustri lucidi and eclipta prostrata on immune function in mice]. | a chinese medicine mixture containing astragalus membranaceus, fructus ligustri lucidi and eclipta prostrata(afe), was fed to mice 9g/kg, 20g/kg, respectively for seven days. observe the effects of afe on the immune function in mice. the experiment showed that the two dosages of afe could obviously raise the conversion percentage of lymphocytes (p < 0.01) and serum igg level (41%-47%) of the mice. the weights of the thymus and spleensed increased in the two groups compared with those in the norm ... | 1992 | 1304546 |
| [effects of astragalus membranaceus and tripterygium hypoglancum on natural killer cell activity of peripheral blood mononuclear in systemic lupus erythematosus]. | natural killer (nk) activity of peripheral blood mononuclear cells (pbmc) from 28 patients with systemic lupus erythematosus (sle) was measured using enzyme-release assay. the sle patients had significantly decreased nk activity in comparing with normal controls. the levels of nk activity correlated with disease activity. pre-incubation of pbmc separately with astragalus membranaceus and tripterygium hypoglaucum or with their mixture considerably stimulated nk cytotoxicity both in sle patients a ... | 1992 | 1301849 |
| shi-quan-da-bu-tang (ten significant tonic decoction), sqt. a potent chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs. | shi-quan-da-bu-tang (ten significant tonic decoction), or sqt (juzentaihoto, tj-48) was formulated by taiping hui-min ju (public welfare pharmacy bureau) in chinese song dynasty in ad 1200. it is prepared by extracting a mixture of ten medical herbs (rehmannia glutinosa, paeonia lactiflora, liqusticum wallichii, angelica sinesis, glycyrrhiza uralensis, poria cocos, atractylodes macrocephala, panax ginseng. astragalus membranaceus and cinnamomum cassia) that tone the blood and vital energy, and s ... | 1992 | 1294861 |
| [inotropic action of astragalus membranaceus bge. saponins and its possible mechanism]. | astragalus membranaceus saponins (ams) 50-200 micrograms/ml had a positive inotropic action on the isolated working heart of rats, but in the case of 30 micrograms/ml the inotropic action turned negative. the contractility recovered after washing out the ams. strophanthin k performed in a similar manner as ams. ams 500 micrograms/ml decreased the resting potential of cultured rat heart cells by 10 mv. the results suggest that ams plays its inotropic role through influencing the na-k-atpase. | 1992 | 1292500 |