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[leptospirosis on the island of reunion. iii. epidemiologic study].in the island of reunion, rodents and wild dogs can be carriers of leptospires. aquatic environmental plays an important part. human contamination is associated with water and sugar cane. animals are infected by numerous serogroups.19836671268
[leptospirosis on the island of reunion. i. human leptospiroses].human leptospiroses in the island of reunion have a common point: they are severe diseases. approximately 50 to 60 cases are biologically diagnosed every year. the number of cases is correlated with rainfall. the predominating serogroup is icterohaemorrhagiae, followed by canicola, grippotyphosa and australis.19836671266
forfeiture of proceeds of drug-related crimes: a british commonwealth perspective.the forfeiture of the proceeds of drug-related offences does not seem to have received much attention as yet from british commonwealth countries. whereas in some of these countries specific legislation exists in relation to forfeiture, in many other countries the act of forfeiture falls within the purview of general criminal law. forfeiture presupposes enquiry and search, two procedures which involve integral aspects of present-day human rights law, and which seem to be impeded at almost every s ...19836556074
[rift valley fever and zinga virus: a pathogenic arbovirus in man and animal new for madagascar].virus zinga strains have been isolated from several pools of mosquitoes collected in perinet area, 130 km far from tananarive, at the institut pasteur of madagascar in 1980. although this virus is pathogenic for man, it seemed to give only a mild illness and did not appear to constitute a problem of public health. but today it is seen in quite a different way; since the who center for arbovirus reference and research of new haven has shown the serologic identity between virus zinga and an anothe ...19846534285
[influenza and lemurs]. 19816282228
[enteroviruses of madagascar. 20 years' activity of the virology laboratory of the pasteur institute of madagascar]. 19806263198
[two cases of ankylosing spondylitis in negroes from indian ocean (author's transl)].are reported: the first one, observed in tananarive, on a 26 years old man born in madagascar, with involvement of sacroiliac articulation and rachis. the second one, observed in marseille on a 20 years old man who was born in la reunion, with serious right coxitis and sacroileitis. in the second case, the investigation of hla b27 antigen was positive. both cases were probably primitive. a review of literature shows unusualness of ankylosing spondylitis in tropical countries.19806251565
arboviruses and lemurs in madagascar: a preliminary note.the epidemiological role played by lemurs in the circulation of arboviruses in madagascar has been studied. from serological (hai) tests, exposure of lemurs to alphaviruses and flaviviruses appears to vary considerably with location and species of lemur; positive tests varied from 0 to 32%. finally, the data concerning the lemurophilic part of the mosquito fauna suggests that some lemur species and man are infected by the same arboviruses, especially west nile virus. the susceptibility of these ...19826125046
can elephants transmit disease to man? 19665950618
[recent survey of leptospirosis on madagascar. contribution to the study of human, bovine and porcine leptospirosis in the southern region]. 19685756585
[the temperature and distribution of human bilharziasis in madagascar]. 19675633316
focality and spatial units of transmission in human malaria. 19715580455
viral investigation of the 1968-69 hong kong influenza epidemic in ceylon. 19705514120
epidemic of influenza in ceylon 1969. 19705514119
paratelphusa rugosa as the second intermediate host of achillurbainia, a trematode transmissible to man. 19715090981
isolation of two strains of dengue type 2 virus from human cases in ceylon. 19725035193
[role of animals and birds as sources of salmonella infections in man (literature review)]. 19704927791
dirofilaria infection in man in ceylon. 19734749081
four more cases of human infection with dirofilaria (nochtiella). 19724659135
entomological aspects of filariasis control in sri lanka.historical events and suitable environmental conditions in the southwestern coastal areas of sri lanka have led to the establishment of a zone of endemic filariasis caused by wuchereria bancrofti and transmitted by culex pipiens fatigans. the previous brugia malayi foci, scattered over widely dispersed areas of the island, were apparently completely eliminated as a result of control of the mansonia vectors by the destruction of the larval host plants in their swamp habitats. control measures by ...19744619057
feeding studies in ceylonese babies.a study of the effects of 4 milk preparations on the early growth of low birth-weight newborns in ceylon is reported. the following parameters were studied: mortality; weight gain; tolerance, as indicated by the incidence of diarrhea and the presence of sugar in the stools; blood glucose levels; and blood urea and serum sodium levels. a powdered and partially skimmed cow's milk, nestogen, was used as it is available in the government hospitals throughout the island. 2 strengths constituted f ...19744499504
human infections with dirofilaria, a filarial parasite of animals in ceylon, with a brief review of recent cases. 19714149857
changes in the prevalence of intestinal parasites in the human population of the seychelles from 1917 to 1977. 19853935786
[identification of the first human leptospira strain in the island of la réunion].the first leptospira strain of the island of la réunion isolated from a patient hospitalized at saint-pierre, is identified l. icterohaemorrhagiae icterohaemorrhagiae. the importance and severity of leptospiroses in the island of la réunion are to be emphasized.19853886179
[first human cases of food-induced botulism in madagascar]. 19863800494
[epidemiologic survey of the cysticercosis endemic on réunion island].the high incidence of cysticercosis was underestimated in reunion island before computed tomography (january, 1984). in 1974, soulayrolles et boyer-vidal found that cysticercosis was responsible for 0.5 p. 100 of the cases of epilepsy. in hospitalized people, routine cranial and muscles radiographies detected: 1/among 242 epileptics: 183 men: 36 positive (19.67 p. 100); 59 women: 9 positive (15.25 p. 100), 2/among 166 non epileptic-related neurological disorders: 106 men, 6 positive (5.66 p. 100 ...19863797934
mobilization of antibiotic resistance genes among farm animals and human hosts in a developing country (sri lanka). 19873629267
natural history of periodontal disease in man. rapid, moderate and no loss of attachment in sri lankan laborers 14 to 46 years of age.this paper describes the initiation, rate of progress of periodontal disease and consequent tooth loss in a population never exposed to any programs or incidents relative to prevention and treatment of dental diseases. the group consisted of 480 male laborers at two tea plantations in sri lanka. the study design and baseline data have been published. at the initial examination in 1970, the age of the participants ranged between 14 and 31 years. subsequent examinations occurred in 1971, 1973, 197 ...19863487557
medical and human-factor aspects of the first fatal helicopter accident in sri lanka. 19873442876
formicophilia, an unusual paraphilia, treated with counseling and behavior therapy.the case of a buddhist man suffering from formicophilia, a rare paraphilia, is presented. rather than aiming at the elimination of the sexual deviation, counseling and behavior therapy were applied to alleviate the patient's feelings of guilt and depression and improve his self-image. the 12-week therapy was successful in achieving these goals and in addition resulted in a dramatic reduction of the paraphilic behavior. gains were maintained at one-year follow-up.19873434651
immunomodulatory activity of an aqueous extract of azadirachta indica stem bark.the interference of an aqueous extract of the stem bark of azadirachta indica with different parts of the human immune system was investigated. the extract showed strong anticomplementary effects which were dose-and time-dependent and most pronounced in the classical complement pathway assay. moreover, a dose-dependent decrease in the chemiluminescence of polymorphonuclear leukocytes was observed and a dose-dependent increase in the production of migration inhibition factor by lymphocytes.19873302545
[study of an influenza epidemic in tananarive (february 1987)]. 19883242424
[arbovirus infections on the island of nosy-be; serologic and entomologic findings].since 1977, the pasteur institute of madagascar has been studying, during six surveys, the arboviruses of nosy-be area, in the north-west of madagascar. 47.2 p. 100 out of 271 human sera and 11.3 p. 100 out of 150 animal sera (mostly from lemurs), tested for antibodies to 16 arboviruses by the haemagglutination inhibition test, are positive. the results show an important prevalence of flaviviruses. west-nile and dengue 1 viruses were probably circulating some years before the surveys. antibodies ...19883242421
[evaluation of the work conducted by the madagascar pasteur institute in the study of human immunodeficiency virus (hiv) seropositivity in that country].since late 1985, the institut pasteur de madagascar has studied the problem of the distribution of hiv in the island. with the approval and cooperation of the malagasy ministry of health, a number of different surveys have been undertaken, particularly of those sections of the population diagnosed as being of "high-risk". in 1987, a malagasy prostitute from the country's second largest port was identified as seropositive. one case of clinical aids was diagnosed in 1988 in a franco-malagasy subje ...19883221789
screening for cytotoxic activity of plants used in traditional medicine.a total of 260 extracts have been prepared from 75 medicinal plant species collected in africa, panama and mauritius. three different concentrations of each extract have been screened in vitro for cytotoxic activity using a colorimetric assay to determine cell survival of human colon carcinoma co115 cells. fifteen plants showed ed50 values between 10.0 and 1.0 micrograms/ml but more significant activities were obtained in 11 (ed50 range 1.0-0.1 micrograms/ml) and 3 (ed50 range 0.1-0.01 microgram ...19883193790
serological examinations of slaughtered animals (cattle and goats) in the slaughter-house of colombo/sri lanka towards antibodies against brucellosis, q-fever, rmsf-rickettsia-group, listeriosis, echinococcosis and adenoviruses.serological examinations of slaughtered animals (76 cattle and 184 goats) in the slaughter-house of colombo/sri lanka revealed antibodies against listeriosis, brucellosis, q-fever, rmsf-rickettsia-group, echinococcus and adenoviruses. as the results show, part of this zooanthroponosis has a role to play in human medicine and human infections are to be expected.19883139493
upper pleistocene fossil hominids from sri lanka.between 1978 and 1983 hominid skeletal remains were collected from the cave sites of batadomba lena and beli lena kitulgala in sri lanka (formerly ceylon). these are the most ancient specimens of anatomically modern homo sapiens found thus far in south asia, radiocarbon dates placing them in the upper pleistocene. morphometric analysis of the remains of some 38 individuals from the two sites indicates that these populations were characterized by medium stature, moderate to pronounced cranial and ...19873111269
modulation of human malaria transmission by anti-gamete transmission blocking immunity.natural plasmodium vivax malaria infections in man evoke anti-gamete transmission blocking antibodies which influence the infectivity of malaria patients to the vector mosquito. in this study, entomological, immunological and parasitological data obtained through the monitoring of an epidemic of human vivax malaria in sri lanka were used in a mathematical simulation to assess the effect of naturally induced transmission blocking immunity on malaria transmission. a mathematical model to describe ...19883076711
[clinical aspects and prognostic factors of icterohemorrhagic leptospirosis in adults. apropos of 249 cases in la reunion].human leptospirosis of the classical and severe icterohemorrhagic type, usually due to the l. icterohaemorrhagiae serogroup, is frequent in la réunion. in a retrospective study conducted between 1980 and 1984 in 249 adult patients, the mortality rate was 13 p. 100. our data and those found in the literature indicate that the main cause of death is pneumopathy, followed by profuse haemorrhages, arrhythmias and cardiovascular collapse. acute renal failure is common and often severe; it facilitates ...19883067293
[viral etiology of acute respiratory infections in madagascan children].a total of 80 nasopharyngeal secretions collected from malagasy children (53 boys and 27 girls) with viral acute respiratory infection, aged from 6 days to 10 year old admitted to the pediatric department of antananarivo general hospital from may to july 1983, were investigated by indirect immunofluorescence method. 54--samples were found positive for respiratory viruses. distribution according age groups and sex has been studied: children belonging to 25-36 month age group and male sex were mor ...19863026268
a field study of infection with human t-cell leukemia virus among asian primates.asian nonhuman primates were surveyed seroepidemiologically for natural infection with human t-cell leukemia virus (atlv/htlv) or a closely related agent. materials from various primates (three genera [macaca, presbytis, and hylobates], 17 species, totalling 1,079 animals) under natural conditions were obtained in the field study. virus infection was determined by the indirect immunofluorescence test using htlv-specific antigens. animals seropositive for htlv were found only among macaques origi ...19852999568
[arboviroses in the region of nosy-bé, madagascar. serologic and entomologic data].since 1977, the pasteur institute of madagascar has been studying, during six surveys, the arboviruses of nosy-be area, in the north-west of madagascar. 47.2% out of 271 human sera and 11.3% out of 151 sera of lemurs, tested for antibodies to 16 arboviruses by the haemagglutination inhibition test, are positive. the results show an important prevalence of flaviviruses. west nile and dengue 1 viruses were probably circulating some years before the surveys. antibodies against sindbis and rift vall ...19882900082
human t-lymphotropic virus type i antibodies in the serum of patients with tropical spastic paraparesis in the seychelles.tropical spastic paraparesis (tsp), a chronic myelopathy of unknown etiology, was studied in the seychelles. human t-lymphotropic virus type i (htlv-i) and human immunodeficiency virus antibodies were determined using an enzyme-linked immunosorbent assay and confirmed with an indirect fluorescent antibody test in serum samples of 20 patients with tsp and 16 controls. test results indicated that 17 patients (85%) and two controls (transverse myelopathy and clinically probable multiple sclerosis) ...19872883962
neuroepidemiology of human t-lymphotrophic virus type-i-associated tropical spastic paraparesis.tropical spastic paraparesis (tsp) is a chronic neurological syndrome of gradual onset involving the pyramidal tracts and upper motor neurons, resulting in weakness and stiffness of the lower extremities, hyperactive tendon reflexes, spasticity, low back pain, and urinary disturbances. clusters of endemic tsp have been noted in africa, the seychelles islands, colombia, and the caribbean. recently, studies have linked human t-lymphotrophic virus type-i (htlv-i) with the endemic form of the diseas ...19892786158
[human leptospirosis in reunion island. a 3-year epidemiological study (1985-1987)].during a three-year period (1985-1987), in reunion island, 252 cases of leptospirosis were clinically diagnosed in humans, and serologically confirmed. the epidemiological study showed a significant male predominance, presence during all ages of life; no month and no geographical zone are spared but maximal incidences are noted during periods of and in localities with the most important rainfall. severe forms are frequent but mortality remains low.19892743523
[malaria in 1988 in a village of the malagasy highland plateaux. epidemiological findings].in 1988, the malaria research unit of the madagascar pasteur institute settled an out-patients clinic in manarintsoa, a village of the highland plateaux where epidemic malaria appeared recently. 2776 consultants presented between january and june. in addition, the 200 schoolchildren were examined thrice. for each individual, clinical examination and thick and thin blood smears were performed. in the out-patients, parasite rates were above 50% each month and in each age group; the mean parasite r ...19892699226
reaching the unreached.embodied in the child survival revolution are ideological, methodological, and organizational innovations aimed at radical change in the condition of the world's children as rapidly as possible. in countries such as sri lanka, child survival and health for all by the year 2000 often seem to be impossible goals, given the tumultuous socioeconomic and political conditions. in sri lanka, the quality of life has been eroded, not enhanced, by the importation of western technology and managerial cap ...19892638906
viral hepatitis in sri lanka. 19892627726
the use of praziquantel in human infection with dipylidium. 19892617586
characterization of anti-complement compounds from azadirachta indica.the crude aqueous extract of azadirachta indica bark possesses an inhibitory activity on both classical (cp) and alternative pathway (ap) activation of human complement. purification of the compounds with the guidance of the ap-inhibitory activity involved extraction with methanol, dialysis, ion-exchange procedures and gel-permeation chromatography. this sequence yielded two polymers, nb-i and nb-ii, one a highly active compound with a relatively low molecular weight (nb-ii) and the other a less ...19892615417
the extraparasitic life cycle of toxocara vitulorum in the village environment of sri lanka.the extraparasitic life cycle of toxocara vitulorum of buffalo in the villages of sri lanka is related to observations on buffalo behaviour, experimental studies on the development and persistence of the eggs in soil and in wallows and the presence of eggs in village locations. calf faeces on soil were rapidly incorporated by insect activity and the eggs developed only slightly slower than in the laboratory. some infective eggs persisted 3-4 cm deep for 17 months, finally dying during a prolonge ...19892588478
[transmission cycles of the west-nile virus in madagascar, indian ocean].virological, serological and entomological research conducted in madagascar since 1975, reveal the wide-spread presence of west-nile virus on the island. this arbovirus has been isolated from humans, parrots and egrets. vectors belong to the genus culex (e.g. cx. decens, cx. quinquefasciatus, cx. antennatus, cx. univittatus), however the virus has also been isolated from aedes and anopheles. serological tests carried out on over 1,600 human and almost 1,000 animal sera, revealed that human being ...19892575365
[evaluation of 30-year-activity of the virology laboratory of the pasteur institute in madagascar (1958-1987)].the authors studied the different activities of pasteur institute virology laboratory since it was created. in general virology laboratory, 1.685 viral strains were isolated from 9.533 studied samples (17.6% of positivity). enterovirus represented 90% of the viral strains. from 2.417 taking of rhino-pharynx, 133 myxovirus were isolated: a/h3n2 represented 76% of them. 10.776 patients, from 36.169 antirabic department consultants, were vaccinated and 600 had an antirabic serotherapy. 2.828 suspec ...19892561255
seroprevalence of human parvovirus b19 infection in sao tomé and principe, malawi and mascarene islands.the prevalence of antibodies to human parvovirus b19 (anti-b19 igg) in sera (n = 577) from sao tomé and principe, malawi and mascarene islands (mauritius and rodriguez islands) was determined by antibody capture elisa. the b19 prevalence was 51.5% on sao tomé and principe, 58.4% in malawi, and 55.0% on the mauritius mainland and 2.2% on rodriguez island, indicating that b19 virus is highly prevalent not only in europe, japan and the americas but also in the african region. rodriguez islands has ...19892550018
[bacterial, viral and parasitological study of a population of chaerophon pumila bats in anjiro, madagascar].this bacterial, viral and parasitical study of the insect eater bats chaerophon pumila allowed to isolate, from stools of 88 of them, 115 bacterial strains to enterobacteriaceae family: some of them were identified as very atypical, rare or potentially pathogenic for man. from salivary glands, brain and blood, 13 viral strains were also isolated: 8 of them were less identified as dakar-bat virus. any parasite was observed.19892517389
genetic relationship among the musk shrews, suncus murinus insectivora, inhabiting islands and the continent based on mitochondrial dna types.cleavage patterns of mitochondrial dna (mtdna) by restriction endonucleases were examined in musk shrews collected at six trapping sites on two japanese and two indonesian islands, on sri lanka, situated close to the indian subcontinent, and on the mainland of east bengal in bangladesh. no variation of mtdnas was found among the japanese and indonesian shrews, despite their geographical isolation by the sera. in contrast, at least six mtdna types were present in the sri lanka and the bangladesh ...19902383245
[serological surveillance of west nile virus infection in a village of the central highlands in madagascar].a serological survey on the frequency of west nile virus antibodies has been carried out in a village near antananarivo. igg antibodies were searched for by enzyme-linked immunosorbent assay on 460 sera collected in december 1988 and on 494 sera collected in july 1989. the prevalence of west nile virus antibodies varied from 13.4% to 21.8% between the beginning and the end of the rainy season. seroconversion was observed in 14.7% of 354 paired serum samples collected in december and july which h ...19902369170
human salmonella and shigella infections in moroni, the capital of great comoro island (1987-1988).over a period of two years 98 cultures of salmonella and 17 cultures of shigella were isolated at the el maarouf hospital, moroni, capital of the comoros. almost half of the isolates were from children under 5 years. salmonella belonged to a limited range of serotypes, s. typhi dominating in adults and s. enteritidis in children, often with bacteraemia. antibiotic resistance was virtually absent in salmonella and without clinical significance in shigella. the high isolation rate of s. enteritidi ...19902291695
[historical epidemiology of malaria in the archipelago of the mascarenes (indian ocean)].the mascarenes islands (mauritius, rodrigues and reunion) have been for the last few centuries a place of rest and convalescence for sailors, soldiers and inhabitants of the other regions of the indian ocean affected by "intermittent fevers". in the middle of the nineteenth century a severe and deadly malaria epidemic occurred first in mauritius and then in reunion island. it took a century to bring the disease under control, but this has in no way diminished the risk of its re-introduction. com ...19902291690
[ecological factors in the renewed outbreak of malaria in madagascar].the new epidemic of malaria which spread on the madagascar high plateau in 1986-1987 is due to the combination of several factors (some of which are analysed by the authors, especially those related to anopheles, parasite and man). the authors compare the situations on the high plateau and on st mary island, on the east madagascar coast, where the malaria is stable. concerning the vector, the most interesting fact is the come-back of anopheles funestus on the high plateau from which it had disap ...19902208464
[the cost of a campaign against malaria. general considerations].malaria is yet one of the major tropical problems and the technical evolution of the malaria campaigns since 90 years is a witness of its complexity. the cost of a programme against malaria, including house spraying, case finding with chemotherapy and chemoprophylaxis for pregnant women, must allow a long-term (10 years) mobilization of resources. in mayotte island (comoro archipelago), the cost of the malaria campaign was, in 1987, about 6 us $ by inhabitant. without man power cost, the house s ...19902208452
malaria transmission and vector biology in manarintsoa, high plateaux of madagascar.to evaluate the factors which determine the transmission level of falciparum malaria, entomological and parasitological surveys were conducted from october 1988 to february 1990 in manarintsoa in the central highland plateaux of madagascar. mosquitoes were collected for 928 man-nights in pit shelters and indoor resting sites. malaria vectors were anopheles arabiensis and an. funestus, with no evidence of the presence of an. gambiae sensu stricto. vectors were mainly exophilic and zoophilic. the ...19902202220
human t cell proliferative responses to plasmodium vivax antigens: evidence of immunosuppression following prolonged exposure to endemic malaria.human t cell proliferative responses, of 33 adult sri lankans convalescing from plasmodium vivax infections, to several p. vivax antigens (i.e. a soluble extract of asexual erythrocytic stage parasites and two cloned antigens that are potential vaccine candidates pv200 and gam-1) were assessed. the peripheral blood mononuclear cell proliferative responses to the soluble extract of p. vivax, as assessed by studying both the proportion of responders and the degree of the response, were significant ...19902196178
characteristics of malaria transmission in kataragama, sri lanka: a focus for immuno-epidemiological studies.parasitological and entomological parameters of malaria transmission were monitored for 17 months in 3,625 residents in a plasmodium vivax malaria endemic region in southern sri lanka; the study area consisted of 7 contiguous villages where routine national malaria control operations were being conducted. malaria was monitored in every resident; fever patients were screened and 4 periodical mass blood surveys were conducted. an annual malaria incidence rate of 23.1% was reported during the perio ...19902184688
anthropophagy and aggregation behaviour of the sandfly phlebotomus argentipes in sri lanka.the visceral leishmaniasis (vl) vector phlebotomus argentipes annandale & brunetti is widely distributed throughout the indian sub-continent and s.e. asia. the absence of vl in areas such as sri lanka has been attributed to the zoophilic nature of p.argentipes, since they were not recorded biting man. field studies on p.argentipes were undertaken in the central highlands of sri lanka, near kandy, in may 1988. male sandflies outnumbered females on cows by 19:1, and were regularly spaced at all de ...19902132972
[malaria vectors and their role in transmission, in manarintsoa in the highland plateaux of madagascar from 1988 to 1990].to evaluate the factors determining malaria transmission level, entomological and parasitological surveys were conducted from october 1988 to february 1990 in manarintsoa, in the central highland plateaux of madagascar. mosquitoes were collected during 928 man-nights of captures, in pit shelters and in indoors resting sites. the malaria vectors were an. arabiensis and an. funestus, with no evidence of the presence of an. gambiae s.s. the vectors were mainly exophilic and zoophilic. the index of ...19902078088
[preliminary study on malaria transmission at the end of the rainy season in mahitsy near tananarive].this survey carried out from march to june 1989, demonstrated the important part of an. funestus in malaria transmission, in mahisty, a village near the malagasy capital city. end of march, the number of an. funestus bites reached 6 per man per night, and only 0.75 for an. gambiae s.l. in march a mean of 23 an. funestus per room were found as indoor resting mosquitoes. one indoor resting an. funestus, caught in june, was positive against p. vivax by elisa. observed of 52 indoor-resting an. funes ...19902078087
[seroepidemiologic survey on plague in an endemic zone: cumulative results: 1987-1990].plague is a bacterial disease, induced by yersinia pestis growth in rodents, with human transmission by fleas. in numerous cases, lymph node reaction is important. this survey (329 patients and contacts) is the most extensive ever realised, associating plasmidic virulence and immunity studies. from the results, we can retain that: all the strains were 47 plasmid+. the immunity was precocious, specific, of high titer and persistent. in conclusion, in plaque endemic zone, high bacillus circulation ...19902078084
[surveillance of influenza in tananarive. 1989].the authors report results of epidemiological survey of influenza in tananarive. this survey is based on respiratory morbidity observed in an interprofessional health center, and virus isolation. two viruses have circulated in 1989: b virus (b/victoria/2/87) during first half-year, and a: a/victoria/36/88 (h1n1) virus during dry season with a pick in november. influenzae has been responsible of grouped sporadic cases without epidemic diffusion.19902078081
possible rift valley fever outbreak in man and cattle in madagascar. 19912068735
the natural history and clinical course of calculus formation in man.this paper describes levels and progression of supra- and subgingival calculus undisturbed by active professional intervention or home care between 1970 and 1985 in sri lanka, or when removed at regular intervals between 1969 and 1988 in norway. in the sri lankan tea laborers, both supra- and subgingival calculus formation started before age 14 years. at 40 years of age, all participants and almost all teeth and tooth surfaces had calculus. tea laborers who both smoked tobacco and chewed betel h ...19912061415
effect of artocarpus heterophyllus and asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients.investigations were carried out to evaluate the effects of hot-water extracts of artocarpus heterophyllus leaves and asteracanthus longifolia whole plant material on the glucose tolerance of normal human subjects and maturity-onset diabetic patients. the extracts of both artocarpus heterophyllus and asteracanthus longifolia significantly improved glucose tolerance in the normal subjects and the diabetic patients when investigated at oral doses equivalent to 20 g/kg of starting material.19912056756
htlv-i in neurological patients from some indian ocean islands. 19912051310
a sri lankan man with eosinophilia, wheezing, and cough. 19912041965
antigenic variations in west nile virus strains isolated in madagascar since 1978.the antigenic interrelationship between 52 madagascan west nile isolates and two prototype viruses (eg101 and g2266) was assessed by an immunofluorescent technique using monoclonal antibodies. this analysis enabled us to define 5 groups of variants, 4 of which were closer to the egyptian strain (eg101) than to the indian prototype (g2266). groups ii and v were dominant whereas strains of groups i and iv were less numerous. one strain belonging to group iii was antigenically similar to the indian ...19901982372
larval survey of surface water-breeding mosquitoes during irrigation development in the mahaweli project, sri lanka.a survey of ground water-breeding mosquitoes was done during 1986-1987 in an area undergoing irrigation development in the mahaweli project of sri lanka. forty-nine species were collected during the 12-mo phase of humans settlement and infrastructure construction, and 42 species during the succeeding 12-mo period under irrigated rice culture. development resulted in the elimination of some preexisting breeding habitats, the modification of others, and the creation of new habits. the overall chan ...19901977912
genetic variation in the cholesteryl ester transfer protein and apolipoprotein a-i genes and its relation to coronary heart disease in a sri lankan population.the influence of variation in the genes for cholesteryl ester transfer protein and apolipoprotein a-i was investigated in 95 patients with coronary heart disease and 95 matched control subjects of south east asian extraction. restriction fragment length polymorphisms (rflps) linked to the cholesteryl ester transfer protein gene taqia and taqib, and to the apolipoprotein a-i gene ssti, were examined to investigate the extent of genetic variation at these loci. none of the alleles defined by these ...19901975178
[the wesselsbron virus, a new arbovirus for madagascar].wesselsbron virus, an african arbovirus group flavivirus, has been isolated in 1989 for the first time in madagascar from aedes circumluteolus collected inside primary forest near the village of marovitsika. serological studies in man using haemagglutination inhibition test have permitted to think that wesselsbron virus have circulated quietly in madagascar. the detection of wesselsbron antibodies in lemurs sets the problem of the biological cycle.19901964039
[impact of the use of larvivorous fish poecilia reticulata on the transmission of malaria in fir of comoros].field tests were conducted in the grande comore island, federal islamic republic of comoros, in order to evaluate the potential of the larvivorous fish poecilia reticulata for the control of the malaria vector anopheles gambiae s.s. due to the high permeability of soil, anopheles breeding sites in all island occurs only in the man-made water reservoirs. the study was carried out from november 1987 to november 1988 within a framework of a malaria and filariasis control programme, supported by who ...19911952700
sperm antimotility properties of a seed extract of abrus precatorius.this study examined the inhibitory effects of a methanol extract of abrus precatorius seeds on the motility of washed human spermatozoa. the extract caused a concentration-related impairment of percentage sperm motility; with the ec50 concentration being 2.29 mg/ml. this effect on motility was essentially irreversible. with the highest concentration tested (20.0 mg/ml), the onset of the antimotility action was almost immediate. in addition, this concentration impaired the functional integrity of ...19911943179
immunomodulatory activity of three sri-lankan medicinal plants used in hepatic disorders.the effects of aqueous extracts of osbeckia octandra whole plant, melothria maderaspatana whole plant and phyllanthus debelis leaves on the human immune system were investigated. the extracts showed strong anticomplement effects on both the classical and alternate pathways of the human complement system in vitro. the effects were dose-dependent and most pronounced in the classical complement pathway assay. the extracts also exhibited a direct dose-dependent inhibition of luminol-induced chemilum ...19911943175
a serologic study of california serogroup bunyaviruses in sri lanka.a seroepidemiologic study of california (cal) serogroup viruses (genus bunyavirus, family bunyaviridae) was carried out on 952 human and 1,834 animal sera collected from different ecological zones of sri lanka (latitudes 5-10 degrees n, longitudes 79-82 degrees e). the sera were screened for neutralizing antibody to lumbo (lum), snowshoe hare (ssh), and trivittatus (tvt) viruses by plaque neutralization tests on vero cells. of 2,786 sera screened, 262 (9.5%) had antibody to one or more viruses t ...19911928574
the significance of low density microfilaraemia in the transmission of wuchereria bancrofti by culex (culex) quinquefasciatus say in sri lanka.laboratory-bred culex quinquefasciatus were fed on carriers with low and moderate densities of microfilariae (mf) of wuchereria bancrofti. in the first series of experiments, mosquitoes were dissected 12 d after feeding. the percentage of infected mosquitoes and the numbers of larvae per infected mosquito were directly proportional to the mf density at the time of feeding. there was an overall high infection rate and a wide distribution of larvae per individual mosquito at all levels, except for ...19911887486
anopheline ecology and malaria infection during the irrigation development of an area of the mahaweli project, sri lanka.a study on adult anopheline ecology and malaria vector incrimination was carried out from 1986 to 1989 during irrigation development in an area of the mahaweli project in eastern sri lanka. eleven potential vector species were collected resting indoors or by using human or bovid bait, and from light trap catches. overall, anopheles vagus (donitz), an. annularis (van der wulp), and an. subpictus (grassi) were the most prevalent, and an. culicifacies (giles) and an. barbirostris (van der wulp) wer ...19911877717
clustering of malaria infections within an endemic population: risk of malaria associated with the type of housing construction.the occurrence of malaria infections due to plasmodium vivax and p. falciparum was monitored in a population of 3,023 people living in six contiguous villages in kataragama, an area of endemic malaria in southern sri lanka, over a period of 17 months. the annual incidence of malaria in this population during the study period was 25.8%. malaria attacks were clustered, occurring more frequently than expected in certain individuals and housing groups and less frequently than expected in others. in ...19911867350
[seroepidemiological study of human leptospirosis at reunion island].in order to evaluate the prevalence of human leptospirosis in reunion island and to identify possible risk factors, a study was realised on a representative population sample of 3.338 persons. the prevalence of leptospirosis, diagnosed by elisa and confirmed by micro agglutination test, was 1.1%. male predominance and higher prevalence in rainy parts of the island, were confirmed. it has not been possible to display risk factors such as housing conditions or professional exercise. the serologica ...19911866480
a mathematical model for plasmodium vivax malaria transmission: estimation of the impact of transmission-blocking immunity in an endemic area.we have developed a multi-state mathematical model to describe the transmission of plasmodium vivax malaria; the model accommodates variable transmission-blocking/enhancing immunity during the course of a blood infection, a short memory for boosting immunity, and relapses. using the model, we simulated the incidence of human malaria, sporozoite rates in the vector population, and the level of transmission-blocking immunity for the infected population over a period of time. field data from an epi ...19911786621
[prevalence of antibodies to west nile virus in youngsters from 5 to 20 years old in madagascar].in 1990 a serological investigation among 3,177 children (5 to 20 years old) sera has been conducted by the pasteur institute of madagascar in several areas of madagascar, in order to evaluate the prevalence of west nile virus antibodies. 29.9% out of human sera tested by elisa for west nile igg antibodies are positive, that shows a rather high level of west nile virus circulation in madagascar. prevalence is increasing with age but no significant difference has been registered among prevalence ...19911764750
genetic complexity of plasmodium vivax parasites in individual human infections analyzed with monoclonal antibodies against variant epitopes on a single parasite protein.monoclonal antibodies against variant epitopes of a highly polymorphic protein (pv200) in schizonts of plasmodium vivax have been used to analyze the variety of genetically distinct populations of parasites present in the peripheral blood of individual p. vivax infections in sri lanka. in 9 out of 10 isolates of freshly drawn p. vivax infected blood from different individuals, parasites of only 1 pv200 serotype was found within each individual infection, even though parasites were serotypically ...19901690521
[longitudinal study on malaria transmission and biology of vectors in the island of sainte marie, on the east coast of madagascar, from 1988 to 1990].a 17-month longitudinal malaria survey was carried out in sainte marie island, on the east coast of madagascar, from november 1988 to march 1990. during 706 man-nights of captures, 46401 mosquitoes belonging to 32 species were caught. sporozoïte rates were calculated by elisa. the malaria vectors were anopheles gambiae sensu stricto, an. funestus and an. mascarensis. an. gambiae was the main vector. it was highly anthropophilic and partially exophilic. transmission by this species mainly occurre ...19911688287
[virus manombo (mg ar 966), a provisionally new arbovirus isolated from culicidae in madagascar].in april 1987, a virus strain was isolated from a pool of mansonia uniformis caught on human bait, in a tropical primary rain forest area of the south-east coast of madagascar. antigenically, this virus may not be related to other known viruses, and constitutes a provisionally new arbovirus called virus manombo.19911688286
immune responses against sexual stages of plasmodium vivax during human malarial infections in sri lanka.during natural infections of p. vivax malaria a variety of immune responses to the infection affect infectivity of the parasites to mosquitoes. sexual stage antigens present in the blood stage parasites induce antibodies which may either enhance or suppress the infectivity of the sexual parasites to mosquitoes. subsequent infections of p. vivax do not, unless occurring within less than 4 months, boost this response indicating a very short immune memory for the relevant antigens. blood infection ...19911688139
rift valley fever on the east coast of madagascar.in march 1990, a rift valley fever virus (rvfv) outbreak was suspected in the district of fenerive on the east coast of madagascar after an abnormally high incidence of abortions and disease in livestock. sera from humans and cattle were tested for rvfv antibodies by immunofluorescence assay (ifa) and elisa-igm capture. sera and mosquitoes collected in the same area were tested for virus isolation by tissue culture and suckling mouse intracerebral inoculation, and for antigen detection by an eli ...19911687082
survey of adult mosquitoes (diptera: culicidae) during irrigation development in the mahaweli project, sri lanka.a survey of adult mosquitoes was done during 1986-1987 in an area undergoing irrigation development in the mahaweli project of sri lanka. the study encompassed two 12-mo phases of settlement and irrigation, respectively. diurnal human bait catches yielded 1,427 female mosquitoes in 27 species. nocturnal collections (human bait, cdc light traps, indoor resting catches) produced a total of 30,491 females in 67 species. comparisons with an earlier survey in the predevelopment forest showed that the ...19911678784
agricultural practices affect arthritis.it has been suggested that boron deficiency in food may be a cause of some arthritis (newnham 1979). epidemiological studies were done to try to ascertain why some countries have more or less arthritis than other countries. jamaica, mauritius, fiji and israel were visited with a view to ascertaining the boron levels of locally consumed food as it was suspected that excessive use of soluble chemical fertilizers had damaged the soils of the sugar producing lands. food grown on these soils were fou ...19911645463
a genetic marker at the glucokinase gene locus for type 2 (non-insulin-dependent) diabetes mellitus in mauritian creoles.the prevalence of type 2 (non-insulin-dependent) diabetes mellitus is high in mauritius, a multiethnic island nation in the southwestern indian ocean. evaluation of candidate genes in the different ethnic groups represents a means of assessing the genetic component. as glucokinase is known to be a key regulator of glucose homeostasis in liver and pancreatic beta-cells, the human gene was isolated and a dinucleotide repeat (ca)n marker was identified at this locus. a polymerase chain reaction ass ...19921644240
the natural history of periodontal disease in man: prevalence, severity, and extent of gingival recession.this paper describes the occurrence and levels of gingival recession in 2 cohorts of individuals participating in parallel longitudinal studies in norway (1969-1988) and sri lanka (1970-1990), covering the age range from 15 to 50 years. in the norwegian cohort gingival recession had begun early in life. it occurred in greater than or equal to 60% of the 20 year-olds and was confined to the buccal surfaces. at 30, greater than or equal to 70% had recession, which still was found mainly on buccal ...19921625148
is anopheles mascarensis a new malaria vector in madagascar?anopheles mascarensis de meillon, 1947, a mosquito that is native to madagascar, is reported for the first time to act as a vector of plasmodium falciparum malaria. from september 1989 to march 1990, 2, 499 an. mascarensis specimens from different regions of madagascar were tested by an enzyme-linked immunosorbent assay (elisa), using monoclonal antibodies against the circumsporozoite (cs) protein of the four human species of plasmodium. the salivary glands of 237 specimens were also dissected. ...19921536380
malaria transmission by anopheles subpictus (diptera: culicidae) in a new irrigation project in sri lanka.indoor resting anopheles subpictus in a new irrigation scheme in sri lanka were investigated during 1989-1990 for malaria infection by dissection and elisa, and human feeding rates by elisa analysis of blood meals. indoor resting abundance was 22.3 females per house per 15-min catch in april-june 1989, 2.2 in november-december 1989, and 7.5 in april-june 1990. elisa-based malaria infection rates (plasmodium vivax and p. falciparum combined) were 1.4% during april-june and 3.2% during november-de ...19921495065
malaria transmission and vector biology on sainte marie island, madagascar.a 17-mo longitudinal malaria survey (november 1988-march 1990) was carried out on sainte marie island, an area on the east coast of madagascar which is frequently visited by tourists. during 706 man-nights of capture, 46,401 mosquitoes belonging to 32 species were caught. sporozoite rates were determined by elisa and incriminated anopheles gambiae giles s.s., an. funestus giles, and an. mascarensis de meillon as vectors of malaria. an. gambiae, the main vector, was highly anthropophilic but larg ...19921495029
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