Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| human papillomavirus and oropharyngeal cancer survival. | 2010 | 20942677 | |
| [human papillomavirus]. | 2010 | 20942076 | |
| evaluation of oncogenic human papillomavirus rna and dna tests with liquid-based cytology in primary cervical cancer screening: the fase study. | the aptima® hpv assay (ahpv) allows detection of 14 high-risk human papillomavirus (hpv) rna types in cervical specimens. until present, the assay has been compared to hpv dna tests only in triage settings. herein, we compare ahpv with a dna assay (hybrid capture® 2; hc2) and liquid-based cytology (lbc; using preservcyt® thinprep liquid pap) in a screening setting (french aptima screening evaluation [fase] study). women (n = 5,006) aged 20-65 were screened by gynecologists in 17 private practice ... | 2010 | 20941740 |
| human papillomavirus e2 protein with single activation domain initiates hpv18 genome replication, but is not sufficient for long-term maintenance of virus genome. | the papillomavirus life cycle is regulated by a family of proteins encoded by the e2 open reading frame; e2 proteins regulate viral gene expression, dna replication and genome maintenance. we have previously shown that the bovine papillomavirus (bpv1) full-length e2 protein forms heterodimers with repressor forms of e2, and these e2 heterodimers serve as activators of transcription and replication during the viral life cycle. in the present study, using the single-chain e2 heterodimer as a model ... | 2010 | 20940072 |
| [comparison of the diagnostic utility from visual inspection with acetic acid and cervical cytology]. | in mexico, cervical cancer is the second leading cause of death in women after breast cancer. the human papillomavirus is associated with intraepithelial lesions, detected up to 99.7% of cervical carcinomas. despite being easy to detect is a condition that many women suffer. | 2010 | 20939236 |
| factors associated with prevalent abnormal anal cytology in a large cohort of hiv-infected adults in the united states. | the prevalence of and risk factors for abnormal anal cytology among men and women with human immunodeficiency virus (hiv) infection have not been extensively investigated. | 2010 | 20925532 |
| asian society of gynecologic oncology workshop 2010. | this workshop was held on july 31-august 1, 2010 and was organized to promote the academic environment and to enhance the communication among asian countries prior to the 2nd biennial meeting of australian society of gynaecologic oncologists (asgo), which will be held on november 3-5, 2011. we summarized the whole contents presented at the workshop. regarding cervical cancer screening in asia, particularly in low resource settings, and an update on human papillomavirus (hpv) vaccination was desc ... | 2010 | 20922136 |
| apropos knowledge and attitudes of adult peruvian women vis-à-vis human papillomavirus, cervical cancer, and the human papillomavirus vaccine. | 2010 | 20885172 | |
| off-label high-risk hpv dna testing of vaginal asc-us and lsil cytologic abnormalities at parkland hospital. | to investigate the frequency and outcome of high-risk human papillomavirus (hpv) dna testing of atypical squamous cell of unknown significance (asc-us) and low-grade squamous intraepithelial lesion (lsil) vaginal thinprep pap tests (tppts). | 2010 | 20885164 |
| cutaneous hpv5 e6 causes increased expression of osteoprotegerin and interleukin 6 which contribute to evasion of uv-induced apoptosis. | human papillomaviruses (hpvs) are small dna viruses, which specifically infect keratinocytes at different body sites. the association between cutaneous squamous cell carcinoma (scc) formation, ultraviolet (uv) irradiation and infection with a high-risk subset of cutaneous hpvs has been postulated although the underlying molecular mechanisms by which hpv may play a role in scc development are not yet fully elucidated. expression of the viral e6 oncoprotein has been shown to interfere with dna dam ... | 2010 | 20884685 |
| prevalence of high-risk human papillomavirus types and cervical squamous intraepithelial lesions in women over 30 years of age in st. petersburg, russia. | cytology-based screening has significantly decreased incidence of and mortality from cervical cancer. high sensitivity of high-risk human papillomavirus (hrhpv) test for the detection of high-grade cervical intraepithelial neoplasia (cin) makes it a useful screening tool, especially in settings where cytology is not available or not quality assured. the study aimed to determine the prevalence of hrhpv and associated cervical lesions in russian women over 30 years of age and to assess usefulness ... | 2010 | 20884314 |
| novaprep(®) vial test is a suitable liquid-based cytology medium for high risk human papillomavirus testing by hybrid capture 2. | liquid-based cytology (lbc) for cervical cancer screening presents the advantage that cytological and virological investigations can be undertaken from the same specimen. nevertheless, the fixative may alter dna integrity and the sample may be inadequate for hpv dna detection. the novaprep(®) vial test (nvt) (novacyt, vélizy-villacoublay, france) is a new device dedicated to lbc which permits an automated cell spreading over slides and an automated cell sampling for molecular analyses. | 2010 | 20884288 |
| triggering of death receptor apoptotic signaling by human papillomavirus 16 e2 protein in cervical cancer cell lines is mediated by interaction with c-flip. | human papillomavirus (hpv) e2 gene disruption is one of the key features of hpv-induced cervical malignant transformation. though it is thought to prevent progression of carcinogenesis, the pro-apoptotic function of e2 protein remains poorly understood. this study shows that expression of hpv16 e2 induces apoptosis both in hpv-positive and -negative cervical cancer cell lines and leads to hyperactivation of caspase-8 and caspase-3. activation of these signaling factors is responsible for the obs ... | 2011 | 20882347 |
| hpv knowledge in mexican college students: implications for intervention programmes. | in order to promote new human papillomavirus (hpv) prevention and detection methods effectively in mexico, it is important to understand how much the population knows about the virus. this study aimed to determine the demographic and behavioural factors associated with hpv awareness and knowledge in a population of mexican college students. with a response rate of 77%, data were collected from 1109 college students aged 17-25 years old at the autonomous university of the state of morelos in 2006 ... | 2010 | 20880104 |
| cervical hpv infection in brazil: systematic review. | to assess the prevalence of human papillomavirus (hpv) infection in women in brazil. | 2010 | 20877926 |
| composite cervical adenocarcinoma composed of adenoma malignum and gastric type adenocarcinoma (dedifferentiated adenoma malignum) in a patient with peutz jeghers syndrome. | an unusual cervical adenocarcinoma is reported in a 50-year-old woman with a history of peutz jeghers syndrome. the carcinoma contained two morphologically distinct and spatially separate components, one comprising typical well differentiated adenoma malignum and the other a moderately differentiated neoplasm, in keeping with gastric type adenocarcinoma. both components were positive for hik1083 and muc6 and negative for p16, and did not contain human papillomavirus. it is believed that such a c ... | 2010 | 20876329 |
| mutational analysis of kinetic partitioning in protein folding and protein-dna binding. | kinetic partitioning between competing routes is present in many biological processes. here, we propose a methodology to characterize kinetic partitioning through site-directed mutagenesis and apply it to parallel routes for unfolding of the ti i27 protein and for recognition of its target dna by the human papillomavirus e2 protein. the balance between the two competing reaction routes can be quantified by the partitioning constant k(p). k(p) is easily modulated by point mutations, opening the w ... | 2010 | 20876193 |
| prevalence of low-risk and high-risk types of human papillomavirus and other risk factors for hpv infection in germany within different age groups in women up to 30 years of age: an epidemiological observational study. | human papillomavirus (hpv) infection is frequent in young women and persistent infection may lead to cervical cancer. therefore, vaccination against hpv is recommended for young women in the age group from 12-17 years in germany. however, epidemiological data on the prevalence of hpv types and risk factors for infection for younger women in germany is scarce. to address this, an observational study was performed in germany including 1,692 women aged 10-30 years. after a routine pap smear, cervic ... | 2010 | 20872721 |
| cervical cancer working group report. | disease burden of cervical cancer in asia was summarized. human papillomavirus 16 is the most oncogenic human papillomavirus type. korea's national cervical cancer screening program targets women aged 30 or over, with coverage of almost 80%. japan has a long history (50 years) of cervical cancer screening, and cytological screening programs have reduced the incidence/mortality of cervical cancer by 70%. but, recent cervical cancer screening coverage is ∼24%. modeling suggested that vaccination o ... | 2010 | 20870919 |
| human papillomavirus-positive basaloid squamous cell carcinomas of the head and neck. | 2010 | 20868902 | |
| [infection of human papillomavirus 16/18 dna in patients with head and neck squamous cell carcinoma and its relationship with expression of ki-67 and p53 protein]. | to detect the infection of human papillomavirus (hpv) 16/18 in patients with head and neck squamous cell carcinoma and explore the relationship between hpv infection and expressions of ki-67 and p53 proteins in tumor tissue. | 2010 | 20868604 |
| medical and surgical approaches to vulvar intraepithelial neoplasia. | vulvar intraepithelial neoplasia (vin) is a precursor to invasive vulvar carcinoma. the two major types of vin, usual and differentiated, differ in epidemiology, pathogenesis, clinical manifestations, pathology, and malignant potential. usual vin commonly occurs in younger women. it is associated with human papillomavirus and tends to have multifocal and multicentric involvement. differentiated vin is frequently associated with benign vulvar dermatoses such as lichen sclerosus and lichen simplex ... | 2010 | 20868402 |
| disparities in human papillomavirus vaccine series initiation among adolescent girls enrolled in florida medicaid programs, 2006-2008. | to better understand the human papillomavirus (hpv) vaccine series initiation among 9-17-year-old female medicaid beneficiaries in florida programs between june 2006 and december 2008 (n = 237,015). | 2010 | 20864008 |
| [a study on the relationship between hpv infection and the oncogenesis of primary squamous carcinoma of the lung.]. | to research the relationship between human papillomavirus (hpv) infection and the oncogenesis of primary squamous carcinoma of the lung. | 1998 | 20863461 |
| changes in knowledge of cervical cancer prevention and human papillomavirus among women with human immunodeficiency virus. | to estimate changes in high-risk women's knowledge of cervical cancer prevention, human papillomavirus (hpv), and hpv vaccination since introduction and marketing of hpv vaccines. | 2010 | 20859159 |
| hla-cw group 1 ligands for kir increase susceptibility to invasive cervical cancer. | inherited genetic polymorphisms within immune response genes have been shown to associate with risk of invasive cervical cancer (icc) and its immediate precursor, cervical intraepithelial neoplasia grade 3. here, we used the transmission/disequilibrium test to detect disease-liability alleles and investigate haplotype transmission of kir and hla class i polymorphisms in a large family-based population of women with cervical cancer and their biological parents (359 trios). the effect of distinct ... | 2010 | 20857097 |
| hpv vaccine acceptance, utilization and expected impacts in the u.s.: where are we now? | human papillomavirus (hpv) vaccines represent a remarkable opportunity for the primary prevention of cervical cancer and other hpv-related diseases. with almost four years of vaccine availability now accrued in the united states (u.s.), data are beginning to accumulate about vaccine utilization patterns and how these may be affected by public opinions about the vaccines. this article describes the burden of hpv infection and related disease in the u.s., and reviews what is currently known about ... | 2010 | 20855941 |
| human papillomavirus infections in laryngeal cancer. | although the association and clinical significance of human papillomavirus (hpv) infections with a subset of head and neck cancers, particularly for oropharyngeal carcinoma, has recently been well documented, the involvement of hpv in laryngeal cancer has been inadequately evaluated. herein we review the currently known associations of hpv infections in diseases of the larynx and their potential for oncogenicity. using several methods of detection, hpv dna has been detected in benign (papillomat ... | 2011 | 20848441 |
| prevalence of high-risk human papillomavirus types (hpv-16, hpv-18) and their physical status in primary laryngeal squamous cell carcinoma. | recently oncogenetic human papilloma virus(hpv) infection has been suggested to promote laryngeal squamous cell carcinoma(lscc). to determine the prevalence and genotypes of hpv infection in laryngeal cancer specimens, 84 specimens from pathologically confirmed lscc patients were studied for the presence of viral dna and possible virus integration into the cellular genome. hpv genotyping was assayed prior to the integration analysis by using two pcr-based assays, including hpv-16 and-18 e7 type- ... | 2010 | 20845999 |
| global proficiency study of human papillomavirus genotyping. | internationally comparable quality assurance of human papillomavirus (hpv) dna detection and typing methods is essential for evaluation of hpv vaccines and effective monitoring and implementation of hpv vaccination programs. therefore, the world health organization (who) hpv laboratory network (labnet) designed an international proficiency study. following announcement at the who website, the responding laboratories performed hpv typing using one or more of their usual assays on 43 coded samples ... | 2010 | 20844222 |
| long-term absolute risk of cervical intraepithelial neoplasia grade 3 or worse following human papillomavirus infection: role of persistence. | infection with high-risk human papillomavirus (hpv) is the main cause of high-grade cervical intraepithelial neoplasia (cin) and cancer. it has been suggested that information about high-risk hpv type-specific infection might make cervical cancer screening more effective. persistent hpv infection could also be a useful screening marker. we estimated the long-term risk of high-grade cin after one-time detection of high-risk hpv dna and after persistent infection with individual high-risk hpv type ... | 2010 | 20841605 |
| a modeling framework for the analysis of hpv incidence and persistence: a semi-parametric approach for clustered binary longitudinal data analysis. | human papillomavirus (hpv) infection is a common sexually transmitted disease of growing public health importance, and over 40 genotypes have been identified in genital infections. current hpv cohort studies often follow participants at pre-determined visits, such as every 6 months, and data generated from such epidemiology studies can be described as clustered longitudinal binary data where correlation arises in two ways: the directionless clustering due to the multiple genotypes tested within ... | 2010 | 20839368 |
| in vivo mechanisms of vaccine-induced protection against hpv infection. | using a human papillomavirus (hpv) cervicovaginal murine challenge model, we microscopically examined the in vivo mechanisms of l1 virus-like particle (vlp) and l2 vaccine-induced inhibition of infection. in vivo hpv infection requires an initial association with the acellular basement membrane (bm) to induce conformational changes in the virion that permit its association with the keratinocyte cell surface. by passive transfer of immune serum, we determined that anti-l1 antibodies can interfere ... | 2010 | 20833377 |
| stopping hpvs dead in their tracts. | vaccines are currently available to prevent infection of the genital tract and subsequent disease for some human papillomavirus (hpv) types, and attempts to develop broadly cross-reactive hpv vaccines are progressing. a recently developed murine model of cervicovaginal hpv infection examines the mechanisms by which antibodies prevent infection in vivo. | 2010 | 20833372 |
| [multifocal epithelial hyperplasia: a familial case]. | multifocal epithelial hyperplasia (meh), or heck disease, is a disease of the oral mucosa rarely seen in spain. it is caused by the human papillomavirus (hpv), and is mainly associated with types 13 and 32. it appears in childhood (3-18 years) and a higher prevalence is reported in women and certain ethnic groups (american indians and eskimos). it consists of a benign, asymptomatic epithelial proliferation in the form of multiple papules of 3-10mm with a normal oral mucosa colour. the case invol ... | 2010 | 20833119 |
| impaired toll-like receptor 7 and 9 signaling: from chronic viral infections to cancer. | hiv-1, hepatitis b virus, hepatitis c virus, and human papillomavirus type 16 cause persistent infections that frequently precede cancer development. virions of these viruses are weak inducers of interferon-α and impair toll-like receptor (tlr)9 function. loss of tlr9 responsiveness also occurs in tumors without viral etiology such as breast, ovary, and head and neck carcinomas. recent reports have suggested that viruses and components of the tumor microenviroment interact with regulatory recept ... | 2010 | 20832362 |
| absence of high-risk human papillomavirus (hpv) detection in endocervical adenocarcinoma with gastric morphology and phenotype. | a subset of endocervical-type mucinous adenocarcinomas (acs) of the uterine cervix exhibit a gastric phenotype and morphology, as reported in cases of minimal deviation ac in which the presence of human papillomavirus (hpv) has been rarely detected. to investigate the hpv-independent pathway of carcinogenesis in cases of gastric-type ac, we investigated the common high-risk hpv (hr-hpv) status in 52 nonsquamous cell carcinomas, using a pcr-based typing method and immunohistochemistry of p16ink4a ... | 2010 | 20829441 |
| [detection and quantification of human papillomavirus genital infections: virological, epidemiological, and clinical applications]. | human papillomaviruses (hpv) are the main risk factor for cervical cancer. by introducing its dna into the genome of infected human cells, the virus expresses two oncoproteins (e6 and e7) that induce inactivation of tumour suppressors and telomerase. hpv infection is extremely common. but most of women will clear the infection over an 8-10-month period without developing any cervical lesion. in fact, it is the persistence of infection that truly exposes to the risk of cervical cancer. hpv testin ... | 2011 | 20828954 |
| prevalence and genotype distribution of cervical human papillomavirus infection in macao. | population-specific epidemiological data on human papillomavirus (hpv) infection are essential for formulating strategies to prevent cervical cancer. the age-specific prevalence of hpv infection was determined among 1,600 women enrolled for cervical screening in macao. a u-shaped age-specific prevalence curve with a first peak (prevalence rate, 10%) at 20-25 years and a second peak (13%) at 51-55 years was observed. co-infections with multiple types were detected in 32.5% of hpv-positive subject ... | 2010 | 20827770 |
| human papillomavirus and tar hypothesis for squamous cell cervical cancer. | 2010 | 20826942 | |
| prevalence of human papillomavirus types in high-grade cervical intraepithelial neoplasia and cancer in italy. | the aim of this multicentric study was to identify human papillomavirus (hpv) type distribution in invasive cervical cancer and high-grade cervical intraepithelial neoplasia 2/3 (cin2/3) in italy. | 2010 | 20826836 |
| randomized healthservices study of human papillomavirus-based management of low-grade cytological abnormalities. | human papillomavirus (hpv)-based management of women with borderline atypical squamous cells of undetermined significance (ascus) or mildly abnormal cervical intraepithelial neoplasia (cini) cervical cytology has been extensively studied in the research setting. we wished to assess safety and health care resource use of a real-life health care policy using hpv triaging. all 15 outpatient clinics involved in the organized population-based screening program in stockholm, sweden screening program w ... | 2011 | 20824706 |
| age-specific prevalence of human papillomavirus by grade of cervical cytology in tibetan women. | human papillomavirus (hpv) is believed to be the most common sexually transmitted infection. however, little is known about the prevalence and distribution of hpv types in china. we aimed to assess the prevalence and the distribution of hpv types as well as risks for abnormal cervical cytology in women who reside in the tibetan autonomous region of china. | 2010 | 20819533 |
| [clinical features and prognosis of cervical cancer in young women]. | to investigate the prevalence, etiology, clinical presentation and pathological features, treatment and prognosis of cervical cancer in young women. | 2010 | 20818083 |
| tumor therapy in mice by using a tumor antigen linked to modulin peptides from staphylococcus epidermidis. | staphylococcus epidermidis releases a complex of at least four peptides, termed phenol-soluble modulins (psm), which stimulate macrophages to produce proinflammatory cytokines via activation of tlr2 signalling pathway. we demonstrated that covalent linkage of psm peptides to an antigen facilitate its capture by dendritic cells and, in combination with different tlr ligands, can favour the in vivo induction of strong and persistent antigen-specific immune responses. treatment of mice grafted with ... | 2010 | 20817012 |
| presence of human papillomavirus infection determined by hybrid capture assay in cervical lesions in a venezuelan population. | the aim of this study was to establish the presence of hpv infection in cervical lesions in a venezuelan population, by hybrid capture assay ii (hca ii), and its association with cytological diagnosis. the study included 1483 cervical samples analysed at laboratorios citomed, caracas, venezuela, from 2005 to 2007. the woman age range was between 20 and 58 years, and the mean age was 28.8. hpv infection was determined using hca ii. the cytological diagnosis of the smears showed lsil in 1120/1483 ... | 2010 | 20815154 |
| hpv-16 e5 down-regulates expression of surface hla class i and reduces recognition by cd8 t cells. | hpv-16 is the major causes of cervical cancer. persistence of infection is a necessary event for progression of the infection to cancer. among other factors, virus persistence is due the viral proteins fighting the immune response. hpv-16 e5 down-regulates mhc/hla class i, which is much reduced on the cell surface and accumulates in the golgi apparatus in cells expressing e5. this effect is observed also in w12 cells, which mimic early cervical intraepithelial progression to cervical cancer. the ... | 2010 | 20813390 |
| safety and immunogenicity of the quadrivalent human papillomavirus vaccine in hiv-1-infected men. | human immunodeficiency virus type 1 (hiv-1)-infected men are at increased risk for anal cancer. human papillomavirus (hpv) vaccination may prevent anal cancer caused by vaccine types. | 2010 | 20812850 |
| re: impact of human papillomavirus (hpv)-6/11/16/18 vaccine on all hpv-associated genital diseases in young women. | 2010 | 20811003 | |
| reasons for non-vaccination against hpv and future vaccination intentions among 19-26 year-old women. | despite cdc recommendations regarding universal catch-up vaccination against human papillomavirus (hpv), only about ten percent of young adult women in the united states have been vaccinated. the purpose of this study was to better understand reasons for non-vaccination among insured 19-26 year-old women and to evaluate future vaccination intentions. | 2010 | 20809965 |
| evaluation of atypical squamous cells on conventional cytology smears: an experience from a screening program practiced in limited resource settings. | the bethesda system (tbs) 2001 has subdivided the category of atypical squamous cells (asc) into: asc-us (undetermined significance) and asc-h (cannot exclude high-grade squamous intraepithelial lesion (hsil)). the present study is an analysis of asc-us and asc-h cases diagnosed in a screening program practiced in limited resource settings. | 2010 | 20806086 |
| middle- and high-school health education regarding adolescent vaccines and human papillomavirus. | we performed a mail-based survey of health education teachers in 6 states with diverse health education environments to better understand health education curricula in secondary schools related to adolescent vaccination and human papillomavirus (hpv) infection. of the 198 respondents (response rate 68%), 66% and 71% reported teaching adolescents about recommended vaccines and hpv, respectively. middle schools were significantly less likely to include these topics in their health curriculum than ... | 2010 | 20801244 |
| treatment of genital warts: facts and controversies. | there are two opposing approaches in the treatment of genital warts: (1) the traditional approach advocates complete elimination of all lesions, and (2) a second approach regards condyloma as merely a cosmetic nuisance. after a long journey through many arguments and scientific papers, we have concluded that many unknowns, uncertainties, and controversies concerning the value of treatment of genital warts in terms of clearing and curing the disease (ie, eradicating the viruses, preventing cancer ... | 2010 | 20797516 |
| local hyperthermia could induce antiviral activity by endogenous interferon-dependent pathway in condyloma acuminata. | local hyperthermia has been successfully used in the treatment of viral warts by mechanisms that have largely remained unclear. using an organotypic culture system, we found that hyperthermia at 42 °c and 45 °c could induce a significant increase in the transcriptional expression of interferon (ifn)-α, ifn-β and ifn-γ, in a temperature-dependent manner in condyloma acuminata (ca), but not in normal skin. accordingly, local hyperthermia could enhance the expression of 2'-5' oligoadenylate synthas ... | 2010 | 20797409 |
| human papilloma virus persistence and neopterin, folate and homocysteine levels in cervical dysplasias. | objective: to investigate the relationship between human papilloma virus (hpv) infection persistence and serum folate, vitamin b12, homocysteine, neopterin levels in cervical dysplasia. study design: through the years 2007-2008, 122 women who have admitted to gynecology clinic were evaluated for cervical cytology, demographical characteristics, hpv infection, serum folate, vitamin b12, homocysteine, albumin, and neopterin levels. results: considering all the cases, the highest percentage of the ... | 2010 | 20740364 |
| modification of human papillomavirus minor capsid protein l2 by sumoylation. | the human papillomavirus (hpv) minor capsid protein l2 plays important roles in the generation of infectious viral particles and in the initial steps of infection. here we show that hpv-16 l2 protein is sumoylated at lysine 35 and that sumoylation affects its stability. interestingly, the sumoylated form of l2 cannot bind to the major capsid protein l1, suggesting a mechanism by which capsid assembly may be modulated in an infected cell. additionally, l2 appears to modulate the overall sumoylati ... | 2010 | 20739540 |
| human papillomavirus infection and anal dysplasia in renal transplant recipients. | immunosuppression is a known risk factor for anal human papillomavirus (hpv) disease, including anal squamous cell carcinoma. additional risk factors for hpv-related disease have not been studied in the renal transplant population. the demographics of anal hpv and associated risk factors were investigated in this population. | 2010 | 20730855 |
| seroprevalence and determinants of eight high-risk human papillomavirus types in homosexual men, heterosexual men, and women: a population-based study in amsterdam. | to determine differences in the seroprevalence of high-risk human papillomavirus (hrhpv) types between men having sex with men (msm), heterosexual men and women, we analyzed seroprevalence and risk factors for 8 hrhpv in the general population of amsterdam, the netherlands. | 2010 | 20729796 |
| human papillomavirus in ameloblastoma. | ameloblastomas are benign epithelial tumors of odontogenic origin, with a high recurrence rate and local aggressiveness. a few preliminary studies have demonstrated hpv presence mainly in peripheral ameloblastomas. the purpose of this study was to detect hpv-dna in intraosseous ameloblastomas. | 2010 | 20727492 |
| prevention of human papilloma virus infection with vaccines. | human papilloma virus (hpv) is present in all the cases of cervical cancer. it can also cause other diseases like genital warts, condylomata accuminata, cervical intraepithelial neoplasia and anogenital cancers. cervical cancer is the second most common cause of death from cancer. to improve the mortality from cervical cancers it is extremely important to prevent the hpv infection. in this review we have discussed the role of hpv vaccines in preventing the hpv infections and so the cervical canc ... | 2010 | 20726203 |
| human papillomavirus and survival in patients with base of tongue cancer. | the incidence of base of tongue cancer is increasing in sweden and the proportion of human papillomavirus (hpv) positive cancer has increased in stockholm, sweden. between 2006 and 2007, 84% of base of tongue cancer cases in stockholm were hpv-positive. the objective of this study was to assess the impact of hpv status on prognosis for base of tongue cancer patients. one-hundred and nine patients were diagnosed with base of tongue cancer between 1998 and 2007 in stockholm county and 95 paraffin- ... | 2011 | 20725995 |
| hpv vaccination's second act: promotion, competition, and compulsion. | developments regarding human papillomavirus (hpv) vaccines will transform hpv vaccination in the united states while simultaneously raising several new policy and ethical concerns. policymakers, vaccine manufacturers, and the public health community must now respond to the presence of competing vaccines that are similar but distinct, particularly with respect to genital wart prevention and the benefits of vaccinating males. this work arises in the shadow of the contentious introduction of the hp ... | 2010 | 20724671 |
| prevalence and stability of antibodies to 37 human papillomavirus types--a population-based longitudinal study. | information about serostability of cutaneous hpv types over time is very limited. we investigated seroprevalence and serostability of 37 different hpv types over 4½ years in an australian population-based study. sera and data were analyzed for 390 people who had never been diagnosed with scc and had blood collected in 1992, 1993 and 1996. eighty-six percent of participants were seropositive to at least one of the 37 hpv types at baseline. hpv-4 was the type with the highest seroprevalence (41%), ... | 2010 | 20723959 |
| inclusion and exclusion in mid-life lesbians' experiences of the pap test. | lesbians are said to feel excluded by sexual health messages that presume heterosexuality, a finding linked to lower levels of papanicolaou (pap) testing. this paper discusses a small, focused qualitative study based in calgary, canada that illuminated mid-life lesbians' experiences and perceptions of pap testing and health. participants indicated that they felt compelled and invited to access pap testing by an inclusive discourse - that of 'mid-life', a period associated with an increased need ... | 2010 | 20721767 |
| human papillomavirus (hpv) vaccine acceptance and perceived effectiveness, and hpv infection concern among young new zealand university students. | two-hundred undergraduate students completed an anonymous questionnaire after viewing a human papillomavirus (hpv) vaccine television commercial. eight-four percent of participants would accept a free hpv vaccine, whereas 47% were unconcerned about future personal hpv infection risk. males were less likely to accept a free hpv vaccine and to be concerned about future personal hpv infection risk. perceived hpv vaccine effectiveness was significantly greater among participants who had previously h ... | 2010 | 20719233 |
| global reduction of cervical cancer with human papillomavirus vaccines: insights from the hepatitis b virus vaccine experience. | worldwide, prophylactic vaccines against two major human cancers are now commercially available: hepatitis b virus (hbv) vaccines (first licensed in 1982) against primary hepatocellular carcinoma and human papillomavirus (hpv) vaccines (first licensed 2006) against cervical cancer. initial implementation strategies for hbv vaccination were not successful in preventing disease in the community: it took 15 years for significant global reduction in the burden of this disease. | 2010 | 20719231 |
| models of cervical screening in the era of human papillomavirus vaccination. | epidemiologic and economic evaluation using simulation modelling can support complex policy decisions, and is an important tool in predicting the future interaction between human papillomavirus vaccination and cervical screening. several categories of screening program evaluation are of interest, including: (1) changes to screening considered over the short term, over which the effects of vaccination should be confined to the youngest age groups (<30 years old); (2) the medium and long-term effe ... | 2010 | 20719228 |
| us physicians' intentions regarding impact of human papillomavirus vaccine on cervical cancer screening. | us cervical cancer screening recommendations have not changed since the human papillomavirus (hpv) vaccine introduction in 2006, but epidemiological and cost-effectiveness studies indicate that recommendations will need to change for fully vaccinated women. we evaluated physician intentions regarding hpv vaccine's impact on future screening. | 2010 | 20719225 |
| human papillomavirus vaccine acceptability among a national sample of adult women in the usa. | in the usa, the human papillomavirus (hpv) vaccine is currently licensed for 9-26-year-old females, but licensure for women over 26 years is being considered. the aim of the current study was to investigate the association of sociodemographic and health-related factors to hpv vaccine acceptability among adult women. | 2010 | 20719219 |
| low rates of free human papillomavirus vaccine uptake among young women. | to determine uptake of quadrivalent human papillomavirus recombinant vaccine (quadrivalent; gardasil((r)), merck, new jersey, usa) offered under optimal conditions to women 18 to 24 years of age, and to identify predictors of uptake. | 2010 | 20719216 |
| human papillomavirus vaccine introduction in vietnam: formative research findings. | formative research is a useful tool for designing new health interventions. this paper presents key findings from formative research conducted in vietnam to guide human papillomavirus (hpv) vaccine introduction. | 2010 | 20719213 |
| cancers attributable to human papillomavirus infection. | although the human papillomavirus (hpv) vaccine was introduced primarily as a cervical cancer prevention vaccine, hpv has a causal role in several types of cancer. this article reviews the epidemiological evidence for the role of hpv in human cancer, and describes australian trends in these cancers. hpv is a necessary cause of cervical cancer. the currently vaccine-preventable subtypes of hpv 16 and 18 are responsible for ~70% of cervical cancer. the introduction of an organised pap smear progra ... | 2010 | 20719211 |
| cervical cancer screening in mediterranean countries: implications for the future. | prompted by feedback from the 34th european congress of cytology (ecc), the practice of including a special symposium in the programme was continued in the 35th ecc in lisbon (2009) by arranging a satellite symposium entitled 'cervical cancer screening in the mediterranean countries'. because of the importance to the future of this discipline, it was felt appropriate to summarize the highlights of this symposium here. cervical cancer prevention strategies in the countries participating in the sy ... | 2010 | 20718841 |
| in vitro activity of dermaseptin s1 derivatives against genital pathogens. | the aim of this study was to evaluate the biological activity of nine dermaseptin-s1 (drs-s1) derivatives (synthesized by solid-phase methods and purified) against different pathogens causing genital infections (trichomonas vaginalis, herpes simplex virus, papillomavirus). the in vitro activity on t. vaginalis was determined by counting the protozoon in a hemocytometer after vital staining with trypan blue; antiviral activity of the compounds was tested on monolayers of vero cells for herpes sim ... | 2010 | 20718719 |
| production and purification of human papillomavirus type 33 l1 virus-like particles from spodoptera frugiperda 9 cells using two-step column chromatography. | the major capsid protein l1 of human papillomavirus (hpv) is essential in construction of recombinant antigen vaccines against cervical cancer. hpv type 33 accounts for about 10% of all hpv infections in asia. the gene encoding the major capsid protein l1 of the high-risk hpv type 33 was isolated from a korean patient and expressed in sf-9 insect cells using a baculovirus expression system. hpv33 l1 protein was isolated by two-step chromatographic purification using strong-cation exchange and ce ... | 2011 | 20716445 |
| assessing the relationship between hiv infection and cervical cancer in côte d'ivoire: a case-control study. | the association between hiv infection and invasive cervical cancer that has been reported may reflect differential prevalence of human papillomavirus (hpv) infection or uncontrolled confounding. we conducted a case-control study in a west african population to assess the relationship between hiv infection and invasive cervical cancer, taking into account hpv infection and other potential risk factors for cervical cancer. | 2010 | 20716343 |
| topical 5-fluorouracil treatment of anal intraepithelial neoplasia in human immunodeficiency virus-positive men. | anal intraepithelial neoplasia (ain), a human papillomavirus (hpv)-induced potential precursor lesion of anal cancer, is frequent among human immunodeficiency virus (hiv)-positive men who have sex with men (msm). so far, only a few prospective studies have been performed on the topical treatment of ain, especially at the intra-anal location. | 2010 | 20716208 |
| impact of vaccinating boys and men against hpv in the united states. | we assessed the public health impact and value of vaccinating boys and men with the quadrivalent hpv vaccine in the united states. we used mathematical population models, accounting for both the direct and indirect protective effects of vaccination. inputs for the models were obtained from public data sources, published literature, and analyses of clinical trial data. compared with a program of vaccinating girls and women only, including boys and men 9-26 years of age would further decrease the ... | 2010 | 20713101 |
| the acceptability of human papillomavirus vaccine among parents and guardians of newborn to 10-year-old children. | the purpose of our study was to evaluate hpv vaccine acceptance among parents and guardians of children aged 0-10 years. | 2011 | 20709581 |
| how parents hear about human papillomavirus vaccine: implications for uptake. | to examine correlates of human papillomavirus (hpv) vaccine awareness and information sources in a state requiring schools to inform parents about hpv vaccine. | 2010 | 20708571 |
| voluntary school-based human papillomavirus vaccination: an efficient and acceptable model for achieving high vaccine coverage in adolescents. | 2010 | 20708557 | |
| evaluation of quality control procedures in an oesophageal cancer cohort study in anyang, china. | we wished to evaluate the efficiency of internal quality control procedures of a cohort study investigating human papilloma virus (hpv) infection as a key exposure factor in oesophageal cancer in anyang, china. this was done by testing 2395 environmental/equipment swab and mock quality control samples from 14 loci on sample collection equipment for human β-globin and hpv dna. human β-globin was present in 3.88% of these samples but no hpv dna was detected. there was no evidence of hpv dna contam ... | 2010 | 20708302 |
| expression of hpv6b l1/ebv lmp2 multiepitope and immunogenicity in mice. | human papillomavirus (hpv) major capsid protein l1 is an important vehicle for the delivery of epitopes. to investigate the expression and immunogenicity of hybridized hpv6b l1 containing multiepitope of epstein-barr virus (ebv) latency membrane protein 2 (lmp2), a recombinant plasmid pcdna3.1(+) containing mammalian codon-optimization hpv6b l1 gene and ebv lmp2 multiepitope was constructed. the ebv lmp2 multiepitope containing t- and b-cell epitope-rich peptides was inserted into c-terminal of ... | 2010 | 20705592 |
| oncogenic human papilloma virus and cervical pre-cancerous lesions in brothel-based sex workers in india. | a community-based cross-sectional study was conducted in brothel-based sex workers of west bengal, eastern india, to determine their oncogenic human papillomavirus (hpv) status and the presence of pre-cancerous lesions. a total of 229 sex workers from three districts of west bengal participated in the study. all the study participants were interviewed with the aid of a pre-tested questionnaire to determine their sociodemographics, risk behaviour and risk perceptions after obtaining informed verb ... | 2008 | 20701853 |
| the role of sexual behavior and human papillomavirus persistence in predicting repeated infections with new human papillomavirus types. | although human papillomavirus (hpv) infections are common in young women, the rate of and risk for repeated new infections are not well documented. we examined the rate of and risks for new hpv detection in young women. | 2010 | 20696663 |
| establishment of an erythroid cell line from primary cd36+ erythroid progenitor cells. | most continuous cell lines with erythroid characteristics are derived from patients with myelogenous leukemia or erythroleukemia. among them, a few cell lines have been reported to be positive for cd36. we tried to establish a continuous erythroid cell line from the primary cd36(+) erythroid progenitor cells (epcs) by the lentivirus-mediated gene transduction system. | 2010 | 20696208 |
| penile cancer--prevention and premalignant conditions. | relatively little evidence is available in the published studies on the prevention of penile cancer and premalignant conditions of the penis. the present review examined the current evidence available in preventing penile cancer and pathologic subtypes of premalignant conditions and their treatment. the recommendations made in the present review formulate the basis of the recent 2009 international consultation on urologic disease consensus publishing group. | 2010 | 20691883 |
| hpv in head and neck cancers among 5-year survivors. | 2010 | 20689367 | |
| detection of human telomerase rna gene in cervical cancer and precancerous lesions: comparison with cytological and human papillomavirus dna test findings. | the aims of this study were to compare the findings of fluorescence in situ hybridization (fish) detection of human telomerase rna gene (hterc) amplification with that of cytological and human papillomavirus (hpv) dna tests and explore the possibility to improve the accuracy of the diagnoses of high-grade cervical intraepithelial neoplasia (cin) and cervical cancer. | 2010 | 20686384 |
| lack of association between extramammary paget's disease and human papillomavirus infection. | 2010 | 20685084 | |
| association between serum cytokine profiles and clearance or persistence of high-risk human papillomavirus infection: a prospective study. | the cytokines that may be associated with the clearance or persistence of high-risk human papillomavirus (hpv) infection in patients with mild dysplasia or less of the uterine cervix were determined. | 2010 | 20683410 |
| current status of human papillomavirus vaccines. | 2010 | 20677402 | |
| vaccination with a human papillomavirus (hpv)-16/18 as04-adjuvanted cervical cancer vaccine in korean girls aged 10-14 years. | the human papillomavirus (hpv)-16/18 as04-adjuvanted cervical cancer vaccine has been demonstrated to be highly efficacious and immunogenic with a favorable safety profile. this study assessed the immunogenicity and safety of the hpv-16/18 as04-adjuvanted vaccine in healthy korean girls aged 10-14 yr. this multi-center, observer-blind trial randomly assigned 321 healthy girls to receive three doses (0, 1, 6-month schedule) of hpv-16/18 as04-adjuvanted vaccine or hepatitis a vaccine. immunogenici ... | 2010 | 20676333 |
| cell cycle-dependent acetylation of rb2/p130 in nih3t3 cells. | the retinoblastoma protein (prb) and the prb-related proteins, p130 and p107, form the 'pocket protein' family of cell cycle regulatory factors. a well characterized function of these proteins is the cell cycle-dependent regulation of e2f-responsive genes. the biological activity of pocket proteins is regulated by phosphorylation and for the founding member prb it has been shown that acetylation also has an important role in modulating its function during the cell cycle. here, we show that hyper ... | 2010 | 20676144 |
| human papillomavirus vaccine coverage. | 2010 | 20674714 | |
| cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of pp2a to induce cell cycle arrest/apoptosis and inhibits tumor progression. | p53 is the most studied tumor suppressor and its overexpression may or may not cause cell death depending upon the genetic background of the cells. p53 is degraded by human papillomavirus (hpv) e6 protein in cervical carcinoma. several stress activated kinases are known to phosphorylate p53 and, among them cyclin dependent kinase 5 (cdk5) is one of the kinase studied in neuronal cell system. recently, the involvement of cdk5 in phosphorylating p53 has been shown in certain cancer types. phosphor ... | 2010 | 20673369 |
| acceptability of prophylactic human papillomavirus vaccination among adult men. | hpv vaccine acceptability was examined as part of a cohort study of hpv infection among adult males. | 2010 | 20671442 |
| prospective study of human papillomavirus (hpv) types, hpv persistence, and risk of squamous cell carcinoma of the cervix. | the link between squamous cell cervical carcinoma and human papillomavirus (hpv) 16/18 is well established, but the magnitude of the risk association is uncertain and the importance of other high-risk hpv (hrhpv) types is unclear. | 2010 | 20671136 |
| human papillomavirus detection and typing in thin prep cervical cytologic specimens comparing the digene hybrid capture ii assay, the roche linear array hpv genotyping assay, and the kurabo genesquare microarray assay. | three methods for the detection of hpv dna were compared in cervical cytologic specimens: the digene hybrid capture ii assay (hc), the roche linear array hpv genotyping assay (la) and the kurabo genesquare microarray (gs). the main goals of the study were to correlate cytology with hpv detection and to determine agreement between assay pairs for hpv detection. thin-prep pap smears were performed and supernates were tested by hc, la, and gs. for specimens reacting with the hpv 52/33/35/58 probe i ... | 2010 | 20670658 |
| overexpression of htert increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines. | to overcome loss of stem-like properties and spontaneous differentiation those hinder the expansion and application of human mesenchymal stem cells (hmscs), we have clonally isolated permanent and stable human msc lines by ectopic overexpression of primary cell cultures of hmscs with hpv 16 e6e7 and human telomerase reverse transcriptase (htert) genes. these cells were found to have a differentiation potential far beyond the ordinary hmscs. they expressed trophoectoderm and germline specific mar ... | 2010 | 20670406 |