Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| induction of humoral antibody response by soluble polysaccharide of cryptococcus neoformans. | 1974 | 4139653 | |
| letter: the pigeon as reservoir for cryptococcus neoformans. | 1974 | 4138408 | |
| cytochemistry of acid mucosubstance and acid phosphatase in cryptococcus neoformans. | 1974 | 4134831 | |
| the morphology of cryptococcus neoformans in human cryptococcosis. a light-,phase-contrast and electron-microscopic study. | 1971 | 4134556 | |
| cryptococcus neoformans: their identification in body fluids and cultures by mucicarmine stain (mayer). | 1972 | 4131417 | |
| cryptococcus neoformans of unusual morphology. | a case of primary cryptococcosis of the lungs was caused by an isolate of cryptococcus neoformans that assumes a giant form in tissue but which has a normal appearance on artificial culture. electron microscopy revealed gross enlargement of the capsule and plasma membranes in the tissue form. | 1973 | 4121033 |
| cisternal puncture and cryptococcal meningitis. | 1973 | 4119510 | |
| cytology for early diagnosis of cryptococcal tracheo-bronchitis. | 1972 | 4118588 | |
| production of diagnostic pigment by phenoloxidase activity of cryptococcus neoformans. | cryptococcus neoformans produces brown pigmented colonies when grown on agar media made from an extract of potatoes and carrots, broad beans (vicia faba), or guizotia abyssinica seeds. since other yeasts do not produce the pigment, these media are useful as differential isolation media for c. neoformans. similar specific pigment was produced by c. neoformans on chemically defined agar media which contained six different substrates of phenoloxidase (o-diphenol: oxygen oxidoreductase ec 1.10.3.1) ... | 1972 | 4118328 |
| biological and electron microscopic changes in gamma radiated cryptococcus neoformans. | 1972 | 4116042 | |
| the ultrastructure of cryptococcus neoformans. | 1971 | 4106826 | |
| an electron microscopic study of cryptococcus neoformans (coward strain). | 1971 | 4101786 | |
| filamentation and endogenous sporulation in cryptococcus neoformans. | 1970 | 4099976 | |
| [adsorption of some basic dyes in pathogenic strains candida albicans and cryptococcus neoformans]. | 1969 | 4099298 | |
| [gastrointestinal manifestations of aids]. | we studied 26 cases of digestive manifestation in aids. the 26 patients were divided into two different epidemiological groups: 13 homosexual men, constituted the first group; no homosexual patient was in the second group which included 6 haitians, 6 africans and a pakistanian. the clinical manifestation were: a watery chronical diarrhea in 17 cases a bloody diarrhea in 2 cases; a loss of weight in the 26 cases; a dysphagia in five cases; a jaundice in one patient (due to kaposi sarcoma of the a ... | 1985 | 4096504 |
| further studies on thymidine kinase: distribution pattern of the enzyme in bacteria. | various micro-organisms (131 strains of 73 species) were studied for their ability to produce thymidine kinase (tk; ec 2.7.1.21). taking the specific tk activity of escherichia coli k12 [specific activity of sonicated cell extracts 95-194 pmol min-1 (mg protein)-1] as 100%, the test organisms had the following relative specific tk activities. in the gram-positive cocci, staphylococcus aureus (21-84%) showed higher activity than staph. epidermidis (1-20%) and streptococcus (1-7%) except for one s ... | 1985 | 4093763 |
| primary cutaneous cryptococcosis. | a 53-year-old man, a pigeon fancier, with long-standing asthma, treated for years with systemic corticosteroids, developed a fast-growing mass on his right wrist. the diagnosis of cryptococcosis was established by histology and culture of tissue which yielded cryptococcus neoformans. oral treatment with ketoconazole for 3 months resulted in a complete cure with residual hyperpigmentation and minute scars. during a 10-month follow-up, the patient was free of recurrences. | 1985 | 4076505 |
| cerebral torulosis: clinical features and correlation with computed tomography. | cryptococcus neoformans (torula histolytica) is an uncommon cause of infection in the central nervous system. we review 15 cases from all over queensland which have presented in the last 6 years. computed tomography (ct) studies were abnormal in 73.5%, with mass lesions and hydrocephalus being the commonest findings. notable findings were: the disproportionate severity of clinical signs and symptoms as compared with the ct findings, which often were either normal or demonstrated only small granu ... | 1985 | 4075717 |
| cryptococcal meningitis: presentation as sudden deafness. | a patient presented with a bilateral profound hearing loss of sudden onset following a two-month neurologic illness. microscopy and culture of cerebrospinal fluid revealed cryptococcus neoformans. treatment with amphotericin b and 5-fluorocytosine failed to restore hearing. auditory brain stem response and electrical promontory stimulation suggest a profound deafness with poor neuronal survival. this is consistent with previous temporal bone histopathology reports in individuals dying of cryptoc ... | 1985 | 4050983 |
| [a case of cryptococcus neoformans meningitis]. | in this paper, a fatal cryptococcus meningitis has been reported. this type of meningitis is quite rare in this country. | 1985 | 4033472 |
| contribution of complement component c5 to the pathogenesis of experimental murine cryptococcosis. | c5-deficient (c5-) mice succumb much sooner after intravenous inoculation with cryptococcus neoformans than do c5-sufficient (c5+) mice. the c5- mice developed acute, fatal cryptococcal pneumonia, whereas the c5+ mice did not. the pneumonia was characterized by lung viable counts in c5- mice up to 1000-fold higher than in c5+, initial sequestration of twice as much 59fe-labeled c. neoformans, and subsequent development of pulmonary edema. chemotaxis of heterophils (pmns) and mononuclear cells in ... | 1985 | 4023888 |
| surgical treatment for fungal infections in the central nervous system. | the hospital records of 78 patients who underwent surgical therapy for fungal infections of the central nervous system (cns) between 1964 and 1984 are summarized. nine different fungal types were identified, but coccidioides immitis and cryptococcus neoformans accounted for most (67.1%) of the infections. a variety of clinical syndromes were seen, including chronic basal meningitis (45 patients), intracranial mass lesions (12 patients), and communicating hydrocephalus (six patients). thirteen pa ... | 1985 | 4020464 |
| cryptococcus neoformans meningitis. | 1985 | 4016912 | |
| [neurocryptococosis and immunosuppression: experimental model in mice]. | in order to accomplish a model for immunosuppression in experimental conditions two lots of 50 young mice were divided into groups of 10, and submitted to dexamethasone ingestion. two experiments were considered in the study. in the first experiment conditions for immunosuppression were established in 50 mice, by per os supply of several concentrations of dexamethasone in the water given for normal daily intake ad libitum. criteria of immunosuppression considered include: hair standing on end; l ... | 1985 | 4015435 |
| lymphocytic interstitial pneumonia associated with the acquired immune deficiency syndrome. | lymphocytic interstitial pneumonitis (lip) is characterized by interstitial accumulation of mature lymphocytes, plasma cells, and reticuloendothelial cells and is often an unremitting process unresponsive to immunosuppressive therapy. the patient described in this report had severe candidal esophagitis and immunologic findings consistent with the acquired immune deficiency syndrome (aids). there was no evidence of pulmonary infection with pneumocystis carinii, cytomegalovirus, mycobacterium aviu ... | 1985 | 4003948 |
| central nervous system involvement in hairy cell leukemia. | a patient with central nervous system involvement by hairy cell leukemia is reported. hairy cells were identified in the cerebrospinal fluid by electron microscopy and by tartrate-resistant acid phosphatase positive staining. intrathecal treatment with methotrexate resulted in neurologic improvement, but was complicated by cryptococcus neoformans meningitis. the leukemic phase of the disease was later successfully controlled by treatment with alpha interferon. surface marker studies indicated a ... | 1985 | 3999626 |
| [digestive manifestations of the acquired immunodeficiency syndrome (aids): study in 26 patients]. | we studied the gastrointestinal manifestations in 26 cases of aids. the patients belonged to two different epidemiological groups: the first group included thirteen french homosexual men, the second group included 6 haitians, 6 africans and a pakistanian, none of them admit homosexual activity. the clinical manifestations were: chronic watery diarrhea in 17 cases, bloody diarrhea in 2 cases; loss of weight in the 26 cases; dysphagia in five cases; jaundice in one patient (due to kaposi sarcoma o ... | 1985 | 3996815 |
| spastic paraparesis due to cryptococcal osteomyelitis. a case report. | skeletal cryptococcosis is an uncommon infection. isolated osteomyelitis due to cryptococcus neoformans is quite rare. only seven cases of skeletal cryptococcosis with involvement of vertebrae but no systemic infection have been reported. in only one was there paraplegia. since vertebral cryptococcosis seems not to have been reported previously in japan, this case of a 50-year-old coal miner successfully treated for paraparesis caused by cryptococcal spondylitis of the ninth, tenth, and 11th tho ... | 1985 | 3995830 |
| chemotactic activity of cerebrospinal fluid in experimental cryptococcal meningitis. | cerebrospinal fluid from rabbits with chronic cryptococcal meningitis was tested for its chemotactic activity towards polymorphonuclear cells and monocytes. csf chemotactic activity was present; it peaked 5-8 days after infection, coinciding with the time when the number of inflammatory cells in csf was greatest. however, little chemotactic activity could be found in the early stages of infection, during the initial ingress of inflammatory cells. the chemotactic activity appeared to be host-deri ... | 1985 | 3992427 |
| infections due to cryptococcus neoformans. | 1985 | 3987945 | |
| solitary pulmonary nodule due to cryptococcus neoformans and mycobacterium tuberculosis. | this report describes a rare combined infection of cryptococcus neoformans and mycobacterium tuberculosis that manifested as a solitary pulmonary nodule in a nonimmunocompromised patient. transthoracic needle aspiration biopsy was initially nondiagnostic, and histopathologic and culture confirmation of the diagnosis was eventually attained after wedge resection of the nodule. an extensive review of the english literature failed to reveal any reported cases of such a combined infection with a sim ... | 1985 | 3985041 |
| dermatologic manifestations of infections in immunocompromised patients. | thirty-one immunocompromised patients (22 renal allograft recipients, 5 patients receiving chronic corticosteroid therapy, and 4 patients undergoing chemotherapy for acute leukemia) with significant dermatologic infection, excluding typical cellulitis and herpesvirus infections, were retrospectively identified over a 12-year period. of these 31 patients, 15 (48%) had infection restricted to their skin, 6 (19%) appeared to have primary cutaneous infection that spread hematogenously to other parts ... | 1985 | 3974441 |
| cardiac lesions in acquired immune deficiency syndrome (aids). | autopsy findings in 41 patients with acquired immune deficiency syndrome (aids) were reviewed. major pathologic findings in the heart were demonstrated in 10 cases, and metastatic kaposi's sarcoma in either the epicardium or myocardium was revealed in 4 cases, including 1 with additional fibrinous pericarditis. nonbacterial thrombotic endocarditis with embolization to major organs was found in three cases, isolated fibrinous pericarditis of unknown origin was found in two and cryptococcus neofor ... | 1985 | 3973269 |
| cholangitis associated with cryptococcus neoformans. | a 15-yr-old girl presented with complaints of right upper quadrant pain and jaundice. elevation of serum alkaline phosphatase, signs of protal hypertension, and computed tomographic scan findings suggested a diagnosis of primary sclerosing cholangitis. however, cultures of the bile and of the common bile duct specimen obtained during a surgical procedure grew cryptococcus neoformans. treatment with amphotericin b was begun. an episode of upper gastrointestinal bleeding, however, led to the hepat ... | 1985 | 3972225 |
| genetic resistance to murine cryptococcosis: the beige mutation (chédiak-higashi syndrome) in mice. | the influence of the bgj and bg2j mutations on the susceptibility of mice to experimental cryptococcosis was studied in inbred mice of the c57bl/6j and c3h/hej strains. although infected animals with the bg/bg genotype had a significantly shorter lifespan than bg/+ or +/+ animals, c3h/he beige-2j mice were less susceptible than c57bl/6 beige-j mice when compared with nonbeige mice of similar background. on days 18 and 19 after infection, quantitation of cryptococci in the brain, liver, and splee ... | 1985 | 3965401 |
| [cryptococcus neoformans meningoencephalitis in aids]. | the risk for aids patients from cryptococcus neoformans is outlined on the basis of a case report on a 28-year old male patient whose disease was complicated by cryptococcosis. beside the description of the diagnosis of cryptococcosis (demonstration of the agent and its antigen), epidemiological associations (habitat of cr. neoformans in fecal matter of birds) and the clinically, mostly not recognized, route of infection via the lungs is stressed. the effective therapy with the combination of am ... | 1986 | 3959495 |
| studies on the occurrence of cryptococcal meningitis in small animals. | 1985 | 3937055 | |
| virulence of cryptococcus neoformans. regulation of capsule synthesis by carbon dioxide. | cryptococcus neoformans is variably encapsulated in vitro, whereas in tissues it develops a large capsule. we observed that cells of a strain with thin capsules, when growing in a standard fungal culture medium, became heavily encapsulated when incubated in serum-free cell culture medium (dulbecco's modified eagle's medium [dme]). capsule size was quantitated physically by measuring cell volume, and chemically by determining the content of a capsular monosaccharide, glucuronate. the co2/hco-3 co ... | 1985 | 3928681 |
| characterization of protein and mannan polysaccharide antigens of yeasts, moulds, and actinomycetes. | antigens in coccidioidin were compared with purified subfractions via tandem immunoelectrophoresis (iep) and by a combination of advancing line and crossed iep. rocket iep was suitable for titrating the reactions and showing the relationship between column fractions. these techniques required multicomponent antisera produced by hyperimmunization over many months and by the use of known standard migration pairs. the iep variations were used to chart the development of antisera against coccidioidi ... | 1985 | 3916766 |
| biotyping of medically important fungi. | 1985 | 3916765 | |
| natural cell-mediated resistance against cryptococcus neoformans: a possible role for natural killer (nk) cells. | 1985 | 3916764 | |
| a cryptococcus neoformans strain from the brain of a wildlife fox (vulpes vulpes) suspected of rabies: mycological observations and comments. | a cryptococcus neoformans strain which in 1983 caused an infection of the central nervous system (cns) in a wildlife fox with rabies-like symptoms was tested for its strain-specific brown colour effect (bce) on guizotia abyssinica creatinine agar and for its ability to assimilate creatinine. both reactions were found to be positive. these results were found to be largely identical with those of 2 out of 3 strains having caused fatal cryptococcosis in 1970, 1979 and 1983 in persons living in the ... | 1985 | 3914796 |
| [experimental ocular cryptococcosis under the influence of time-limited kidney failure--a pathohistological study]. | this animal experiment is characterized by a missing virulence of cryptococcus neoformans strain a94 (isolated from bird manure) for the immunocompetent mouse after intraperitoneal injection and following hematogenous dissemination into all organs including the central nervous system (cns) and by the induction of a renal failure of short duration by intramuscular injection of glycerine. in 50% of the group of 80 animals damaged in such a way ocular cryptococcosis was found in association with th ... | 1985 | 3914795 |
| [initial cerebrospinal fluid in cryptococcus neoformans meningoencephalitis]. | 1985 | 3914052 | |
| [digestive kaposi's sarcoma in patients with kidney transplantation--report of 2 cases]. | malignant tumors occur with greater frequency in patients with kidney transplants. kaposi's sarcoma (ks), a rare vascular neoformation, represents approximately 3% of them. its uncertain etiology appears to respond to: a chronic antigen stimulation by the transplanted tissue, to a depression of immune responsiveness, to the direct oncogenic action of the immunosuppressive agents, to the activation of oncogenic viruses or to a genetic predisposition of other possible factors. the clinical evoluti ... | 1985 | 3911716 |
| [a simple method for performing yeast carbohydrate assimilation test]. | a modified auxanographic method was employed to perform carbohydrates assimilation test for 25 strains of yeasts representing the following 8 species: candida albicans, c. glabrata, c. krusei, c. parapsilosis, c. stellatoides, c. tropicalis, cryptococcus neoformans, and rhodotorula glutinis. the results obtained were analyzed by comparing with the conventional auxanographic method, and it was found that the modified method was more accurate, rapid and easy in reading. the modified method was obv ... | 1985 | 3910369 |
| [anatomicopathological findings relating to fungal infections: considerations on their increase and microbiological findings]. | 2,366 consecutive autopsies carried out at the institute of anatomy and histopathology of the university of genova over the last 10 years are re-examined. 33 cases of visceral mycosis were found (a frequency of 1.4%). the following factors were considered: number and location of fungal infection, morphological characteristics of mycetes responsible, host tissue reaction, relationship with any other disease manifestation or predisposing factors. it is emphasized that these infections are increasi ... | 1985 | 3908979 |
| chemical characterization of capsular polysaccharide from cryptococcus neoformans serotype a-d. | during a study of serotyping of cryptococcus neoformans, we found that the type strain of c. neoformans (cbs 132) was serotype a-d. this strain agglutinated with both factor 7 serum (specific for serotype a) and factor 8 serum (specific for serotype d) in our serotyping system. therefore, we investigated the chemical structure of the antigenic capsular polysaccharide of this strain. the soluble capsular polysaccharide was obtained from the culture supernatant fluid by precipitation with ethanol. ... | 1985 | 3908888 |
| [cerebrospinal fluid diagnosis of meningeal cryptococcosis]. | cryptococcosis must be taken into account as a cause of basal meningitis. along with a case report, clinical signs and guiding cerebrospinal fluid findings are evaluated. special attention is paid to csf-cytology, which provides important information in terms of identification and clinical course of the disease. for the first time c. neoformans, yielded from csf-samples, was investigated by means of scanning electron microscopy, and compared with yeast cultured in laboratory. | 1985 | 3908261 |
| [novel n-pyrazolylsalicylamides with antifungal activity]. | a number of new n-pyrazolylsalicylamides were prepared by fusion of phenyl salicylate and aminopyrazoles. the condensation reaction is influenced by the substitution at the c-4 position of the aminopyrazole. all the substances obtained were tested for antifungal activity against cryptococcus neoformans and candida albicans. it was found that their fungitoxicity is dependent on the structural feature. | 1985 | 3908143 |
| treatment of systemic mycoses with ketoconazole: in vitro susceptibilities of clinical isolates of systemic and pathogenic fungi to ketoconazole. | ketoconazole was tested in vitro in three different media against 69 isolates of pathogenic fungi by using a macro-broth dilution procedure. the dimorphic systemic pathogens were highly susceptible, with most isolates of blastomyces dermatitidis and histoplasma capsulatum being inhibited and killed by concentrations less than or equal to 0.39 micrograms of ketoconazole/ml. most isolates of coccidioides immitis were also inhibited or killed by 0.39 micrograms of ketoconazole/ml; however, several ... | 1985 | 3905985 |
| large cryptococcus neoformans isolated from brain abscess. | cryptococcus neoformans yeast cells 40 to 60 micron in diameter were seen in an india ink preparation made from a human brain abscess specimen. in culture at 25 degrees c, uniform 5-micron-diameter yeast cells were produced. inoculation into mice produced yeast cells up to 40 micron in diameter, and brain heart infusion broth culture at 35 degrees c produced yeast cells about 25 micron in diameter. a relationship of yeast cell diameter to incubation temperature is suggested. | 1985 | 3905847 |
| adrenal pathology in the acquired immune deficiency syndrome. | adrenal pathology was examined in 41 autopsied patients with the acquired immune deficiency syndrome. this represents the largest series and the first study with quantitation of adrenal cortical necrosis. in 32 cases clinical data were analyzed for features of adrenal insufficiency. common clinical findings included vomiting, diarrhea, fever, hypotension, and hyponatremia. none of the 32 patients showed characteristic skin hyperpigmentation. two patients were suspected premortem to have adrenal ... | 1985 | 3904401 |
| characterization of pathogenic constituents of cryptococcus neoformans strains. | we examined seven strains, comprising five serotypes, of cryptococcus neoformans to determine what constituents of the organisms are responsible for pathogenicity and virulence in balb/c mice. c. neoformans strains were divided into three virulence classes by survival rates after intravenous inoculation of 1 x 10(5) or 1 x 10(7) viable cells, and virulence was found not to be correlated with serotype or capsular size. c. neoformans cells resisted phagocytosis in different degrees in the presence ... | 1985 | 3900645 |
| in vitro binding of natural killer cells to cryptococcus neoformans targets. | nylon wool-nonadherent splenic cells from 7- to 8-week-old cba mice were further fractionated on discontinuous percoll gradients. enrichment of natural killer (nk) cells in percoll fractions 1 and 2 was confirmed by morphological examination, by immunofluorescent staining, and by assessing the cytolytic activity of each percoll cell fraction against yac-1 targets in the 4-h51cr release assay. cells isolated from each percoll fraction were tested for growth-inhibitory activity against cryptococcu ... | 1985 | 3899938 |
| effects of cyclosporine in experimental cryptococcal meningitis. | we studied the effects of cyclosporine on experimental cryptococcal meningitis. like cortisone, cyclosporine depressed the highly effective defense mechanisms of normal rabbits against inoculated cryptococcus neoformans, causing them to develop progressive, fatal cryptococcal meningitis. unlike cortisone, which causes a striking reduction in leukocytes in cerebrospinal fluid, cyclosporine depressed mononuclear cell function rather than numbers. interleukin 2, a primary target for the immunodepre ... | 1985 | 3899932 |
| cryptococcosis in the acquired immunodeficiency syndrome. | the clinical course and response to therapy of 27 patients with cryptococcosis and the acquired immunodeficiency syndrome were reviewed. cryptococcosis was the initial manifestation of the syndrome in 7 patients, and the initial opportunistic infection in an additional 7. meningitis was the commonest clinical feature (18 patients). blood cultures and serum cryptococcal antigen were frequently positive. in patients with meningitis, leukocyte count, protein level, and glucose level in cerebrospina ... | 1985 | 3898951 |
| [primary pulmonary cryptococcosis]. | 1985 | 3898251 | |
| disseminated cryptococcosis in a patient receiving chronic haemodialysis. | systemic infection with cryptococcosis neoformans is described in a young man receiving maintenance haemodialysis. the organism was identified in thin sections of a cervical lymph node using resin embedding and silver staining. there were no predisposing factors other than uraemia. his clinical infection responded to the combination of oral 5-flucytosine and a total of 2.5 g of intravenous amphotericin b. he remains free of relapse after 30 months. | 1985 | 3898055 |
| cutaneous cryptococcosis in three cats. | cutaneous cryptococcosis was diagnosed in 3 cats. no other organ involvement was found. one cat has remained healthy after surgical excision of the cryptococcal skin lesion. one cat was euthanatized after diagnosis. the third cat was treated successfully with a 5-month course of ketoconazole. | 1985 | 3897159 |
| sampling and isolation of cryptococcus neoformans from indoor air with the aid of the reuter centrifugal sampler (rcs) and guizotia abyssinica creatinine agar. a contribution to the mycological-epidemiological control of cr. neoformans in the fecal matter of caged birds. | in february and march 1984, cryptococcus neoformans was detected in the manure and ambient air of a volery in the berlin zoo in which a palm cockatoo (probosciger aterrimus) was kept. both times, 5 colony-forming units of cr. neoformans could be isolated on the differential medium, guizotia abyssinica creatinine agar, from 40 1 of air aspirated by the reuter centrifugal sampler (rcs). the absence of a concurrent growth of moulds was found to be of special importance for the optimal isolation of ... | 1985 | 3895777 |
| susceptibility of congenitally immunodeficient mice to cryptococcus neoformans. | 1985 | 3895244 | |
| modulation of murine natural killer cells by cryptococcus neoformans. | 1985 | 3895239 | |
| serologic diagnosis of focal pneumonia caused by cryptococcus neoformans. | cryptococcal antigen was detected in the serum of 3 patients with biopsy-proved cryptococcus neoformans pneumonitis. it is possible that the specificity of this antigen test will allow the serologic diagnosis of cryptococcal pneumonia and obviate the need for invasive procedures. | 1985 | 3893246 |
| cure of cryptococcal infection during continued immunosuppressive therapy. | cryptococcus neoformans is a significant pathogen in immunosuppressed patients. in renal transplant recipients receiving prednisone, the development of cryptococcosis is associated with a poor prognosis. when such patients develop cryptococcosis they pose a particularly difficult clinical dilemma since withdrawal of prednisone, to facilitate cure of their fungal infection, may predispose to loss of their transplanted kidney. we report our experience with cryptococcal infection in 13 renal transp ... | 1985 | 3889977 |
| studies on the isolation of cryptococcus neoformans from fruits and vegetables. | 1985 | 3889639 | |
| role of the latex agglutination test for cryptococcal antigen in diagnosing disseminated infections with trichosporon beigelii. | 1985 | 3889173 | |
| the role of lumbar puncture in the evaluation of dementia: the durham veterans administration/duke university study. | the use of lumbar puncture (lp) and cerebrospinal fluid (csf) analysis in the routine, initial evaluation of patients with dementia continues to be questioned. this is especially true in the investigation of infectious causes of dementia. to explore this question further, the authors performed a retrospective analysis of 672 hospitalized patients specifically evaluated for dementia. lp and csf analysis were performed on 402 patients (60 per cent); routine bacteriologic, acid-fast, and fungal cul ... | 1985 | 3889117 |
| detection of a trichosporon beigelii antigen cross-reactive with cryptococcus neoformans capsular polysaccharide in serum from a patient with disseminated trichosporon infection. | latex beads coated with anti-cryptococcus neoformans antibody were agglutinated by serum from a bone marrow transplant recipient having a disseminated infection caused by trichosporon beigelii. the cryptococcal latex agglutination titer in the serum of the patient rose to 1:2,560 by the time of his death. necropsy confirmed the disseminated trichosporon infection and absence of c. neoformans. cell wall extracts of the isolate of the patient and two additional strains of t. beigelii agglutinated ... | 1985 | 3889042 |
| production and regeneration of protoplasts from cryptococcus. | protoplasts were quickly and efficiently produced from both varieties of cryptococcus neoformans and from c. laurentii by use of the multi-enzyme product novozym 234. conditions for regeneration of protoplasts are described. dna yield from the novozym-produced protoplasts was superior to that from snail gut enzyme-derived protoplasts. | 1985 | 3887604 |
| evaluation of the new mycotube test-kit for yeast identification. | the performance of a modified mycotube test for the identification of yeasts was evaluated using standard biochemical tests as reference. one hundred and eighty strains belonging to 12 medically important species (15 strains each) were tested. the overall rate of identification was 72%, and rose to 87.8% when macroscopic and microscopic morphologic features were also considered; a 100% rate was obtained with candida albicans, candida krusei, candida parapsilosis, candida pseudotropicalis, candid ... | 1985 | 3886377 |
| [cryptococcosis in a red fox (vulpes vulpes)]. | 1985 | 3885939 | |
| ultrastructure of cryptococcus neoformans in the cerebrospinal fluid of a patient with cryptococcal meningitis. | the ultrastructure of cryptococcus neoformans in the cerebrospinal fluid, which was obtained from a patient suffering from systemic lupus erythematosus and cryptococcal meningitis, before treatment and on the 10th and 20th day after the start of treatment was studied. numerous cryptococci were detected in their cerebrospinal fluid before treatment. however, in most of them their biological activity was low and their organelles were not clear. a few yeasts preserved well their organelles. such ce ... | 1985 | 3885042 |
| occurrence of diploid strains of cryptococcus neoformans. | a mating between niacin and pantothenate auxotrophs of cryptococcus neoformans gave a few prototrophic progeny that were self-fertile. these were uninuclear but contained twice as much dna as the parental strains. segregation of nutritional markers was observed upon sporulation. we conclude that these self-fertile strains are diploids. | 1985 | 3882667 |
| genetic resistance to murine cryptococcosis: increased susceptibility in the cba/n xid mutant strain of mice. | in a survey of 301 normocomplementemic inbred mice (belonging to nine different strains: balb/cn nu/nu and nu/+, cba/n, c57bl/ksj, c57br/cdj, cba/caj, brvr, dw/+, and c57bl/6j) for natural resistance to cryptococcus neoformans, cumulative survival values were found to range from 12 to 22 days. when the average organ weights of infected animals were compared with reference values obtained in uninfected mice of the same age and genetic lineage, the following changes were documented. in the cba/n s ... | 1985 | 3880724 |
| disseminated cryptococcosis presenting as thyroiditis. fine needle aspiration and autopsy findings. | a 47-year-old diabetic ethanol and intravenous drug abuser presented with symptoms and signs indistinguishable from subacute thyroiditis. after cultures of cerebrospinal fluid grew cryptococcus neoformans, the organism was recognized in a review of a fine needle aspirate of the thyroid. postmortem examination documented extensive thyroid inflammation and fibrosis secondary to involvement by widely disseminated c. neoformans. fungal infection is an uncommon cause of thyroiditis, and the need for ... | 1985 | 3859146 |
| [2 cases of mycotic infection caused by cryptococcus neoformans]. | the authors present two cases of cryptococcus neoformans disease in two young persons. its appears, in the first case, a diffuse ganglionnary and cutaneous lesion with an evolutive meningo-encephalic localization, and in the second case it appears only a meningitic lesion. these two observations are characterized by the apparition of the infection in a immunodepression patient and by an unfavorable evolution in spite of the treatment. | 1986 | 3800500 |
| neuropathology of acquired immunodeficiency syndrome (aids). analysis of 22 brazilian cases. | the neuropathologic study of 22 brazilian cases of acquired immuno-deficiency syndrome (aids) was performed. thirteen cases (59%) showed neuropathologic lesions. these included infection by toxoplasma (n = 4), cryptococcus neoformans (n = 3), viral encephalitis (n = 4), primary lymphomas (n = 2), isolated cerebral infarct (n = 1), and reactive gliosis (n = 1). in 2 cases, primary lymphoma and viral encephalitis were associated. axonal spheroids in the gracilis and cuneatus nuclei were present in ... | 1986 | 3794749 |
| the thoracic surgical spectrum of acquired immune deficiency syndrome. | the acquired immune deficiency syndrome has presented a complex and, as yet, unsolvable spectrum of pulmonary disease characterized by bizarre infections, pneumothoraces, respiratory distress, and death. thirty-eight patients underwent 49 surgical procedures during 42 months. ages of the patients ranged from 24 to 56 years. surgical procedures included tracheostomy, closure of air leaks, mediastinoscopy, lobectomy, open lung biopsy, and esophagogastrectomy. hospital mortality was 10 of 38 (24%); ... | 1986 | 3784593 |
| ascorbic acid specific utilization by some yeasts. | one hundred and eighty strains of yeasts belonging to 17 genus and 53 species were screened for their ability to grow on ascorbic acid and iso-ascorbic acid as the sole carbon source. most of the tested strains (157) were unable to grow on either compound. strains of seven species of the genus cryptococcus, of two candida species, of filobasidiella neoformans, trichosporon cutaneum, lipomyces starkeyi, hansenula capsulata, and one strain of aureobasidium pullulans were able to grow on ascorbic a ... | 1986 | 3779527 |
| [cryptococcus neoformans infection in aids]. | 1986 | 3743458 | |
| antifungal activity of ketoconazole with emphasis on zoophilic fungal pathogens. | the antifungal activity of ketoconazole was studied against fungal pathogens associated with various mycotic infections in animals. a concentration of 10 micrograms of ketoconazole/ml of medium proved fungicidal to trichophyton verrucosum. the same concentration acted as a strong fungistat against the majority of the tested dermatophytes. yeasts were generally more sensitive than yeast-like pathogens. ketoconazole also proved fungicidal against pityrosporon canis and strongly inhibitory on crypt ... | 1986 | 3729122 |
| intraventricular therapy of cryptococcal meningitis via a subcutaneous reservoir. | intraventricular administration of amphotericin b for meningitis due to cryptococcus neoformans is usually reserved for selected, seriously ill patients with recurrent disease. between september 1973 and november 1983, 10 of 23 patients treated for cryptococcal meningitis at memorial sloan-kettering cancer center received intraventricular amphotericin b through subcutaneous reservoirs, in addition to systemic therapy. the value of intraventricular amphotericin b was assessed in the 13 patients t ... | 1986 | 3728551 |
| bacteremia and fungemia in patients with acquired immune deficiency syndrome. | patients with acquired immune deficiency syndrome (aids) are known to have identifiable host defense deficiencies, especially deficiencies in cell-mediated immunity. they are at increased risk for developing infections of the bloodstream caused by cryptococcus neoformans and salmonella species. however, bacteremias caused by other enteric gram-negative rods and pseudomonas aeruginosa are found less frequently in patients with aids than in patients without aids (p less than 0.001 and p less than ... | 1986 | 3728378 |
| [infections of the central nervous system in malignant hemopathies]. | central nervous system (cns) infections in immunocompromised hosts are often accompanied by subtle disorders because immunosuppression usually decreases the inflammatory response. cns infections in immunocompromised patients are usually caused by organisms different from those found in the general population. the organism causing cns infection in an immunocompromised host can often be predicted if the type of immune abnormality of the patient is known. the common causes of cns infection in immun ... | 1986 | 3726388 |
| [disseminated cryptococcosis in 2 aids patients. a contribution to cryptococcosis diagnosis in aids]. | in two aids patients (homosexual men) microscopical demonstration of cryptococcus neoformans in samples obtained by puncture of the liver (n = 1) and additionally of the spleen (n = 1) led to the diagnosis of systemic cryptococcosis. using the india ink method capsulated cryptococcus neoformans cells could also be detected in cerebrospinal fluid (csf) and urine. concomitant culture of the fungus from tracheal secretion, csf, urine and faeces confirmed the diagnosis of a disseminated infection; t ... | 1986 | 3720562 |
| cryptococcal pneumonia in a patient with sickle cell disease. | we present the findings in a patient having sickle cell disease who developed multilobar pneumonia. cultures of bronchial aspirates and histologic specimens grew cryptococcus neoformans. there was neither spontaneous clearing of the infection nor a response to bactericidal antibiotics. the patient had no underlying malignant neoplasm or immunodeficiency as indicated by history, physical examination, and specialized tests of humoral and cell-mediated immunity. | 1986 | 3709257 |
| use of cerebrospinal fluid lactic acid concentration in the diagnosis of fungal meningitis. | a patient with a several year history of normal pressure hydrocephalus was found to have an infection owing to cryptococcus neoformans. cryptococcal infection was not suspected until typical cells were observed in a wright's stained smear of cerebrospinal fluid (csf). a review of past medical findings in this patient showed elevated csf values for lactic acid and protein. this case prompted us to review the use of lactic acid as an indicator of fungal meningitis and compare it to other more comm ... | 1987 | 3688826 |
| cryptococcosis in a pup. | disseminated cryptococcosis was diagnosed as the cause of death of a 2-week-old pup. cryptococcus neoformans was isolated from the dam's vaginal discharge, but not from the dam's milk, blood, feces, or environment. during succeeding months, c neoformans was isolated repeatedly from the dam's vagina, even though vaginitis was not evident. one year after the death of the 2-week-old pup, cryptococci could not be isolated from the dam's vagina, and evidence of cryptococcosis was not detected in pups ... | 1987 | 3679958 |
| cutaneous cryptococcal infection presenting as vulvar lesion. | a woman aged 60, who had been immunosuppressed since receiving a renal transplant 17 years before, developed a painless ulcerated lesion on her right labia majora. cryptococcus neoformans was demonstrated by culture and biopsy of the lesion. this is the first reported case of a genital skin lesion caused by c neoformans. | 1987 | 3679221 |
| [cryptococcoma of the adrenal gland]. | the case is described of a 49-year-old man who developed cryptococcal meningo-encephalitis ten months before his death. six months later complicating hydrocephalus occurred which required the implantation of a ventriculo-peritoneal shunt. a further four months later the patient, who was receiving anticoagulation therapy due to deep vein thrombosis, died from intraventricular cerebral haemorrhage. in a blood culture taken shortly before his death, growth of cryptococcus neoformans was detected. a ... | 1987 | 3659876 |
| meningitis due to cryptococcus neoformans biovar gattii in a zairean aids patient. | 1987 | 3622501 | |
| acquired immune deficiency syndrome (aids) in brazil. necropsy findings. | according to the 15 autopsies performed at the department of pathological anatomy, escola paulista de medicina, são paulo, brazil, it was confirmed that acquired immunodeficiency syndrome (aids) occurs preferably in young homosexual males, who die in a short period of time of the disease, which leads to a consumptive state verified by cachexia of the cadavers. the most affected organs of this series were the lungs and encephalum, exactly the ones responsible for the immediate cause of death. in ... | 1987 | 3620018 |
| role of natural killer cells in resistance to cryptococcus neoformans infections in mice. | previous studies have suggested a possible role for natural killer (nk) cells in resistance to some fungal infections, including cryptococcus neoformans infections. the role of nk cells in early clearance of c neoformans from tissues and in long-term survival was studied in mice following intravenous inoculations of the organism. mice treated with anti-asialo gm1 antiserum to temporarily reduce nk activity demonstrated an increase in colony-forming units (cfu) of c neoformans in the lung 24 hour ... | 1987 | 3618730 |
| cryptococcal tonsillitis in a patient with chronic lymphocytic leukemia: an unusual manifestation of cryptococcal disease. | we present a case of chronic tonsillitis in a patient with chronic lymphocytic leukemia. despite empiric radiation and antibiotic therapy, the patient's sore throat and tonsillar enlargement persisted. excisional biopsy of the involved tonsil revealed the presence of cryptococcus neoformans. blood cultures also yielded cryptococcus. specific antifungal therapy resulted in cure. to our knowledge, this is the first case report of cryptococcal infection of the tonsil. this case illustrates the pitf ... | 1987 | 3618590 |
| cryptococcal infection of the spine. a case report. | osseous infection due to cryptococcus neoformans is rare. a case of paraplegia due to vertebral cryptococcal infection in a child is reported. | 1987 | 3603270 |
| [laboratory and clinical study of intravenous miconazole]. | laboratory and clinical study was carried out on miconazole (mcz), a new synthetic imidazole. the antifungal activity of mcz was studied and expressed as mics for clinical isolates. the drug proved to have the highest activity against cryptococcus neoformans, with mics of no more than 0.16 micrograms/ml for all isolates of this species. mics of torulopsis glabrata were 0.08-5 micrograms/ml for all isolates and those of candida albicans and candida tropicalis were 5-20 micrograms/ml for more than ... | 1987 | 3599380 |
| description of a case of rhinosporidiosis in spain. | rhinosporidiosis is reviewed, and the first autochthonous case in spain is presented (site: in the nasal cavity of a 19-year-old male from a rural background). diagnosis was established morphologically after eliminating the possibilities of cryptococcus neoformans, coccidioides immitis, and chrysosporium crescens. clinico-pathological features are described. preparations were stained with hematoxylin-eosin, pas, and methenamine silver, and studied for fluorescence. certain aspects of the epidemi ... | 1987 | 3561472 |
| cryptococcosis in kashmir. | 1987 | 3553929 | |
| [electron microscopy demonstration of the capsule of cryptococcus neoformans]. | 1987 | 3553928 |