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effect of antilymphocyte serum on animals experimentally infected with histoplasma capsulatum or cryptococcus neoformans.the anti-mouse and anti-guinea pig antilymphocyte sera (als) prepared for this study were shown to contain cytoxic and leucoagglutinating antibodies, and were capable of producing severe lymphopenia in these animals. guinea pigs treated weekly with als were more susceptible to development of fatal infection when inoculated with histoplasma capsulatum. no fatalities occurred in guinea pigs infected with equal doses of h. capsulatum but treated with normal rabbit serum (nrs) or saline. the time ne ...19695361216
improvement in laboratory diagnosis of pulmonary cryptococcosis.a new differential colour medium prepared with an extract of potatoes and carrots produced ochre-brown pigmentation in cryptococcus neoformans colonies, identical to that obtained with guizotia abyssinica seed extract. the pigment formation was observed to be specific for this pathogenic yeast in a survey of 534 yeast-positive specimens during routine diagnostic work; among 47 c. neoformans-positive specimens were 27 sputa and bronchial aspirations, many overgrown by common yeasts.detection of c ...19695348876
development and evaluation of agglutination and fluorescent antibody procedures for the identification of cryptococcus neoformans. 19655334781
a study of white blood cell and antibody response in mice infected subcutaneously with cryptococcus neoformans. 19655334780
epidemiological and immunological studies of cryptococcus neoformans.walter, jinks e. (university of pittsburgh, pittsburgh, pa.), and robert w. atchison. epidemiological and immunological studies of cryptococcus neoformans. j. bacteriol. 92:82-87. 1966.-the complement-fixation fluorescent-antibody test provided a means of differentiating between antibodies of cryptococcus neoformans and candida albicans. the test was applied to the sera of 134 pigeon fanciers for detection of antibodies to c. neoformans only. about 22% were positive as compared with 3% of a cont ...19665328755
cryptococcus neoformans: ecology and immunology. 19695311973
[identification of cryptococcus neoformans in human cases in minas gerais]. 19655295011
[meningitis caused by "cryptococcus neoformans". (apropos of a clinical case)]. 19665216678
[visceral torulopsis neoformans infection]. 19655215579
in vitro sensitivity to amphotericin b of cryptococcus neoformans isolated in thailand. 19715171413
[occurrence of flocculation reaction with cryptococcus neoformans antigen in the most frequent forms of leukemia]. 19715136008
a survey of zoo aviaries for the presence of histoplasma capsulatum and cryptococcus neoformans. 19715129433
[epidemiologic study of cryptococcus neoformans in mexico]. 19715124656
pigment production of cryptococcus neoformans grown with extracts of guizotia abyssinica.brown pigment(s) formed in cryptococcus neoformans when grown on media containing extracts of the seeds of guizotia abyssinica cannot be extracted by common organic solvents or by 6 n hcl or 2 n naoh. a similar pigmentation was observed in c. neoformans when grown on a medium containing caffeic acid isolated from the hydrolyzed methanol extract of g. abyssinica seeds. its methyl ester and the diacetate thereof, as well as the following structurally related compounds, 3-hydroxytyramine, 3,4-dihyd ...19715119209
bacterial and fungal flora of seagull droppingsd in jersey.in jersey 166 fresh and 122 dried seagull droppings were obtained and studied locally and in london for the presence of bacteria and fungi of potentially pathogenic nature. there were no salmonella or shigella bacteria isolated from the two groups but there was a high proportion of candida albicans obtained from the fresh material (21.7%) and only 1.6% from the dry faeces. cryptococcus neoformans and histoplasma capsulatum were not found in either the dry or fresh droppings. the normal bacterial ...19715104846
meningoencephalitis due to hyphae-forming cryptococcus neoformans. 19715099781
charcoal particle agglutination test for detection of antibody to cryptococcus neoformans: a preliminary report. 19715094496
[meningoencephalitis due to cryptococcus neoformans]. 19715088868
[enzyme chemical studies of cryptococcus neoformans in the brain of rats]. 19664962041
the effect of mammalian and avian sera on the growth of cryptococcus neoformans. 19674960216
survey of poultry, dogs, cats, and monkeys for the presence of salmonella and cryptococcus neoformans. 19664959965
relationship of cryptococcus neoformans to pigeons in milwaukee, wisconsin. 19664959230
cryptococcal meningitis in a case of reticulum cell sarcoma. 19714949798
identification of yeasts in clinical microbiology laboratories. 19714949754
[epidemiology and microbiology of endemic systemic mycoses]. 19714949704
in vitro antifungal activity of clotrimazole (bay b 5097).the in vitro antifungal activity of clotrimazole (bay b 5097) was compared with those of amphotericin b, griseofulvin, nystatin, and pyrrolnitrin. the inhibitory activity of clotrimazole against most systemic pathogens was comparable to that of amphotericin b; minimal inhibitory concentrations of the two drugs for blastomyces dermatitidis, histoplasma capsulatum, sporothrix schenckii, cryptococcus neoformans, and coccidioides immitis were in the range of 0.20 to 3.13 and 0.10 to 6.25 mug/ml, res ...19714949484
viability of cryptococcus neoformans in gastrointestinal tract of chickens. 19714948523
[cryptococcus neoformans: pigment formation on polyphenols]. 19714947982
[animal experiment with cryptococcus neoformans isolated from a patient with chronic meningitis. 1]. 19714945460
effect of relative humidity on survival of candida albicans and other yeasts.individual blastospores of candida albicans were deposited on the surface of 50-mm membranes (millipore corp.) and placed within sealed glass chambers at various relative humidities (rh). after 48 hr, virtually all cells maintained at 100 and 10% rh had survived, but 84% of the cells maintained at 60% rh failed to develop into colonies when transferred to sabouraud medium. no morphological abnormalities could be observed in cells surviving low rh values, but their initial rate of multiplication ...19714943276
primary cutaneous cryptococcosis. 19714943217
survival of a patient transplanted with a kidney infected with cryptococcus neoformans. 19714934356
an atypical strain of cryptococcus neoformans (san felice) vuillemin 1894. ii. cryptococcus neoformans var. gattii var. nov. 19704933034
[serological tests on semi-wild pigeons and on pigeons immunized with killed bacterial antigen for antibodies against cryptococcus neoformans (with a contribution to the fluorescence microscopic test for complement fixing antibodies)]. 19714929057
histopathological observations in experimental cryptococcosis caused by a hypha-producing strain of cryptococcus neoformans (coward strain) in mice. 19714928768
morphological variations of a hypha-forming strain of cryptococcus neoformans (coward strain) in tissues of mice. 19714928767
bovine mastitis caused by cryptococcus neoformans. 19704927160
value and interpretation of serological tests for the diagnosis of cryptococcosis.maximal serological diagnosis of cryptococcosis may be accomplished through the concurrent use of three tests: the latex agglutination (la) test for cryptococcal antigen, and the indirect fluorescent antibody (ifa) and tube agglutination (ta) tests for cryptococcus neoformans antibodies. these tests were applied to 141 serum and cerebral spinal fluid specimens from 66 culturally proven cases of cryptococcosis and to 42 sera from normal subjects and from patients with other systemic mycotic disea ...19684881961
survival of cryptococcus neoformans in the gastrointestinal tract of pigeons following ingestion of the organism. 19684870969
fluorescent-antibody reagent for the identification of cryptococcus neoformans.a sensitive and diagnostically applicable conjugate for the rapid and accurate detection and identification of cryptococcus neoformans has been developed. c. neoformans rabbit antisera were produced by 14 daily intravenous injections of 36 million cells for a total dosage of approximately 500 million cells. cross-staining reactions with species of cryptococcus other than c. neoformans, as well as with candida species, were eliminated by adsorption of the c. neoformans conjugate with cells of c. ...19684868860
cryptococcus neoformans. 3. inhibition of phagocytosis.isolated nonhydrolyzed cryptococcal polysaccharide is a rather specific potent inhibitor of the phagocytosis of cryptococcus neoformans by human leukocytes in vitro. when an encapsulated strain of c. neoformans was cultured in the nonencapsulated state, the rate of phagocytosis was three times greater than when the encapsulated form was used. our theory that capsular material plays a role in the pathogenesis of cryptococcosis requires (i) that c. neoformans exist in soil in a nonencapsulated sta ...19684866104
cryptococcus neoformans. ii. phagocytosis by human leukocytes.twenty-four per cent of the leukocytes from healthy human subjects phagocytized an encapsulated strain of cryptococcus neoformans. phagocytosis was approximately three times more effective with nonencapsulated mutants of c. neoformans. when the mutants reverted to the encapsulated state, the percentages of phagocytosis decreased. these data indicate that cryptococcal polysaccharide inhibits the phagocytosis of c. neoformans by human leukocytes.19674862192
in vitro activity of 5-fluorocytosine against candida and torulopsis species.one hundred yeasts were studied. tests included detailed identification and determination of 24- and 48-hr minimal inhibitory concentrations and minimal fungicidal concentrations of 5-fluorocytosine (5-fc). final identifications included 57 isolates of candida albicans, 15 isolates of c. tropicalis, 13 isolates of c. parapsilosis, 7 isolates of torulopsis glabrata, 3 isolates of c. guilliermondii, 2 isolates each of c. stellatoidea and cryptococcus neoformans, and 1 isolate of candida krusei. tw ...19734799552
amphotericin pharmacophobia.five cases are described in which fear of the possibly hazardous effects of giving amphotericin to patients with kidney disease resulted in death from progressive infection by an amphotericin-sensitive fungus (cryptococcus neoformans in three cases, blastomyces dermatitidis in one case, and histoplasma capsulatum in one case).19734758449
growth of cryptococcus neoformans within human macrophages in vitro.macrophages cultured from human peripheral blood monocytes were infected with cryptococcus neoformans in vitro. although c. neoformans were actively ingested, there was no detectable intracellular killing by macrophages. over 2 days or more, intracellular fungi grew more rapidly than a corresponding inoculum of extracellular cryptococci growing in tissue culture medium containing human serum. macrophages were induced to develop into cells which appeared to be activated by morphological and phago ...19734697791
cryptococcal and other forms of mycotic meningitis. 19724630730
deep mycoses in india. a critical review. 19724630705
pulmonary cryptocococcis followed by pulmonary tuberculosis. a case report. 19724627831
dissociated deficiency of cellular immunological function, cryptococcal meningitis and acute myeloid leukaemia. 19724623441
cryptococcal dermotropism in the rhesus monkey. 19724621964
[diagnosis of the two indigenous deep yeast infections, candidiasis and cryptococcosis (author's transl)]. 19744619500
cell-mediated immunity in cryptococcosis. 19744619352
isolation of cryptococcus neoformans from soil contaminated with pigeon droppings in bangkok. 19744618564
[effects of escherichia coli or its endotoxin on intravenous infection of cryptococcus neoformans duke in mice]. 19744618139
occurrence of cryptococcus neoformans in pigeon excreta in enugu (nigeria). 19734617968
[antimycotic effect of astrantia-, eryngium- and sanicula saponins]. 19744617889
therapy of deep-seated fungal infections with 5-fluorocytosine. 19744616675
[case of isolated pulmonary cryptococcosis]. 19724615649
[position and interest of deep-seated mycoses among the infectious diseases in man (author's transl)]. 19744614190
morphologic aspects in primary cryptococcosis of the skin. 19744614091
isolation of cryptococcus neoformans from pigeon habitats in poona area. 19734613715
letter: mononuclear cells killing cryptococcus. 19744612379
[dnase activity of yeast strains]. 19744612365
[experimental infection of pigeons and chickens with cryptococcus neoformans and further epidemiologic studies]. 19744612362
effects of corticosteroids on human monocyte function.this report examined the effect of corticosteroids in vitro on human peripheral blood monocytes, essential cells in both immune and nonimmune cellular defense mechanisms. monocyte chemotaxis in response to sera, escherichia coli filtrate, and lymphokine chemotactic factor was markedly reduced (p < 0.01) by hydrocortisone succinate (hcs) at 16 mug/ml. methylprednisolone succinate and unesterified hydrocortisone produced similar impairment of monocyte chemotaxis while two drugs which unmodified do ...19744612058
cryptococcal meningitis treated with 5-fluorocytosine and amphotericin b. 19744611967
antimicrobial agents. xxi. dependence of antifungal activity on the structure of the side chain in the pyrimidine group. 19744611876
the influence of antifungal antibiotics on some determinants of virulence in candida albicans and cryptococcus neoformans cells. 19744611784
the interaction of phagocytes and the large-sized parasite cryptococcus neoformans: cytochemical and ultrastructural study. 19744611641
septic arthritis due to nonencapsulated cryptococcus neoformans with coexisting sarcoidosis. 19744611430
nasal cryptococcosis. 19744611401
acid phosphatase levels in the genus candida and their application to the taxonomy and identification of pathogenic candida species. 19744610820
cryptococcosis involving the postorbital area and frontal sinus in a horse. 19744609239
pulmonary cryptococcosis: a case report. 19744608790
[apple and apple-juice as a nutrient substratum for cryptococcus neoformans (author's transl)]. 19744608471
[detection methods of cryptococcus neoformans in cryptococcal infection (author's transl)]. 19744607901
cryptococcosis of bone. case report. 19744606398
pleural involvement in cryptococcosis. 19744604920
experimental cryptococcosis of the skin. 19744604460
cryptococcus neoformans osteomyelitis: case report of two patients. 19744604282
clinical-pathological conference. primary amebic meningoencephalitis in a healthy 7-year-old boy. 19744604236
antiviral agents. chemical modifications of a disulfide antibiotic, acetylaranotin. 19744602597
epidemiology of cryptococcosis: ii. evaluation of patients' environment. 19744600687
epidemiology of cryptococcosis: i. environmental distribution of cryptococci in oklahoma. 19744600686
cryptococcus meningitis--a case report. 19744599901
cryptococcal osteomyelitis treated with 5-fluorocytosine. 19744599881
fatal aplastic anemia resulting from flucytosine. 19744599079
variables influencing susceptibility testing of cryptococcus neoformans to 5-fluorocytosine.the minimum inhibitory concentration (mic) of 5-fluorocytosine (5-fc) was determined for 65 isolates of cryptococcus neoformans by using a twofold serial tube dilution method. the mic was profoundly influenced by incubation temperature, inoculum size, and duration of incubation. by using a standard set of test conditions, 100% of 49 pretreatment isolates of c. neoformans were susceptible to 10 mug of 5-fc per ml or less, and 9 (56%) of 16 isolates recovered during or after 5-fc therapy were mass ...19734598611
5-fluorocytosine resistance in cryptococcus neoformans.isolates of cryptococcus neoformans from six patients were obtained before and after unsuccessful therapy with 5-fluorocytosine (5-fc). post-therapy isolates exhibited massive and stable 5-fc resistance. the frequency of drug-resistant mutants in susceptible isolates of c. neoformans was <0.001% (70.4 +/- 17.9 per 10(7) cryptococci), whereas mutant frequencies in resistant isolates approached 100%. non-drug-induced, spontaneously appearing 5-fc resistant mutants were documented in four susceptib ...19734597734
[on a case of meningoencephalitis caused by cryptococcus neoformans]. 19734597262
the role of the classical and alternate complement pathways in host defenses against cryptococcus neoformans infection. 19744596700
evaluation of a commercial latex agglutination test kit for cryptococcal antigen.two dozen crypto-la kits for detecting cryptococcus neoformans capsular polysaccharide antigens were evaluated. ten kits proved reliable for detecting and titering antigen in clinical materials. fourteen kits were found to be inadequate.19744596394
observations on the occurrence of cryptococcus neoformans in an aviary, using niger-seed creatinine agar and membrane-filtration technique. 19734595824
histologic response to capsule-deficient cryptococcus neoformans. 19734594090
skin testing of guinea pigs and footpad testing of mice with a new antigen for detecting delayed hypersensitivity to cryptococcus neoformans.this study was undertaken to evaluate the potential of a cryptococcal culture filtrate antigen, cryptococcin c184, for detecting delayed hypersensitivity in cryptococcus neoformans-injected animals. the antigen was tested on guinea pigs which had received saline or c. neoformans and on animals sensitized to histoplasma capsulatum, blastomyces dermatitidis, candida albicans, or sporothrix schenckii. a delayed-type hypersensitivity response was elicited by cryptococcin c184 in c. neoformans-inject ...19744593343
[pigeons as a natural reservoir of cryptococcus neoformans strains]. 19744592845
stimulation of phagocytosis of cryptococcus neoformans in human cryptococcal meningitis. 19744592662
editorial: cryptococcosis: an appraisal of some recent developments. 19734592589
observations on the natural habitats of cryptococcus neoformans and nocardia asteroides. 19734592588
antibody-dependent killing of cryptococcus neopormans by human peripheral blood mononuclear cells. 19744589453
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