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design of skin flaps with a new technique using templates.patterned templates were constructed to assist in planning, performing, and teaching skin flap surgery. templates can be used to design geometrically accurate flaps and to consider different flap orientation strategies. they can be used to align flap tension forces in proper relationship with relaxed skin tension lines.20123312330
expression of campylobacter jejuni invasiveness in cell cultures coinfected with other bacteria.enteroinvasive salmonella, shigella, and escherichia coli strains were found to exert an effect which rendered campylobacter jejuni capable of intracellular localization in epithelial cells in vitro. when monolayers of hep-2 or a-549 cells were challenged with pure cultures of c. jejuni or campylobacter coli, none of the eight strains tested invaded the cells. in contrast, four of these strains were able to localize intracellularly when the cells were challenged with a mixture of campylobacters ...19873312015
introduction of shigella flexneri 2a type and group antigen genes into oral typhoid vaccine strain salmonella typhi ty21a.for protection against dysentery caused by shigella flexneri 2a, an in vivo-constructed recombinant plasmid with genes specifying the s. flexneri type and group antigens located near the pro (min 6) and his (min 44) chromosomal markers, respectively, was made and transferred to the gale salmonella typhi strain ty21a. strain ty21a carrying this recombinant plasmid was shown by immunological and biochemical analyses to express the s. flexneri 2a type and group antigens. mice immunized with this va ...19873312013
entry of shigella flexneri into hela cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation.the enteroinvasive bacterium shigella flexneri expresses a plasmid-mediated capacity to penetrate into nonphagocytic cells. by using 7-nitrobenz-2-oxa-1,3-diazole-phallacidin (nbd-phallacidin), a fluorescent dye which specifically stains microfilaments, we observed condensations of filamentous actin underneath the plasma membrane of hela cells which interacted with the invasive isolate m90t. as demonstrated by indirect immunofluorescence with the antimyosin monoclonal antibody cc-212, myosin acc ...19873312007
atrio-ventricular block associated with shigella flexneri infection. 19873311739
[steroidogenesis in ovarian tumors]. 20123311390
evaluation of bronchodilator responsiveness in mechanically ventilated patients.airway pressure, flow, and volume were measured before and after administration of aerosolized metaproterenol during controlled mechanical inflation and stepwise deflation of the relaxed respiratory system in 13 mechanically ventilated patients. an increase in passive expiratory flow at constant respiratory system recoil pressure was considered evidence of bronchodilatation. in 10 patients, at a respiratory system recoil pressure of 6 cm h2o (vp6), expiratory flow increased 21 to 500% above preb ...20123310772
warfarin and the biochemistry of the vitamin k dependent proteins.we have reviewed the biochemistry of the normal and warfarinized vitamin k-dependent coagulation proteins, both individually and as members of their respective macromolecular enzyme complexes. much has been learned in the past 10-15 years about the molecular mechanisms of coagulation. however, we have only scratched the surface and are beset by a number of interesting challenges. clearly, we must begin to dissect the other vitamin k-dependent macromolecular enzyme complexes as has been done for ...20123310538
[morphological changes in the lungs after single whole-body irradiation in rabbits].morphological changes in rabbit lungs were studied after whole-body nonuniform irradiation (24 gy) the head and the abdomen being shielded. acute pneumonitis was shown to develop between the 17th and the 24th day after irradiation. no pulmonary fibrosis was registered 60 days following irradiation. embolised megakaryocytes were found in the lung capillaries between the 8th and the 24th day after irradiation.19873306764
chronobiology and epidemiology.epidemiology and chronobiology are two emerging scientific disciplines of the 20th century. in the united states and certain european and asian countries, epidemiology is a well-developed science; however, in many countries the field is not yet well practiced. too, in several european countries and certain centers in the united states, chronobiology is quite well known and respected as a science. yet, in many countries this field is just now being recognized. although epidemiologists are concern ...19873306581
okt3 rescue in refractory renal rejection.a community hospital-based transplant program participated in the study of orthoclone okt3 as a treatment for refractory renal rejection. a total of 16 patients receiving varied oral immunosuppressive regimens, and developing steroid-resistant acute rejection, were treated with okt3. thirteen of the 16 patients completed a 10-day course of therapy with reversal of rejection in all 13. rerejection occurred in 1 of the 13 patients; the remaining 12 have normal renal function. fever, chills, and di ...20123306423
a new chromogenic test for the detection of urokinase in the genus shigella.a simple test for detection of urokinase in shigella is described. the test is performed by suspending a loopful of bacteria in 100 microliters of a buffered 1mm solution of benzoyl-beta-alanyl glycyl-arginyl-4-nitroanilide acetate (chromozym u). enzymatic activity is revealed by formation of a yellow colour after 24 h of incubation at 37 degrees c. the test is able to differentiate serotypes of shigella dysenteriae, shigella flexneri, shigella boydii. the results suggest the possibility of incl ...19873306294
[demonstration of anti-laminin antibodies in the serum of healthy subjects].antibodies directed against laminin, a glycoprotein of basement membranes, have been sought for in the sera of 347 healthy subjects by a method relying on the agglutination of laminin-coated latex particles. fifty-five subjects (15.9%) hae been found to be positive, 37 with a titre of 2, 14 with a titre of 4 and 4 with a titer of 8. applied to 106 patients whose a renal biopsy had been examined by immunofluorescence, the test yielded positive results in 91% of patients with linear deposits as co ...20123304440
[reaction of the hematopoietic system in mice to the administration of virulent and avirulent strains of shigella flexneri 2a].the influence of live bacteria and antigenic preparations of virulent and avirulent stains of shigella flexneri 2a on the endogenous splenic colony formation in murine hematopoietic cells has been studied. the different stimulating activity of live microbial cells of virulent and avirulent strains shigella flexneri 2a and their antigenic preparations on the endogenous colony formation has been shown. the effect observed depends on the preparation doses and time of their administration before irr ...19873304434
molecular cloning and expression of a synthetic dna coding for the antimicrobial protein of bull seminal plasma.a dna carrying the coding sequence for the antimicrobial protein from bull seminal plasma (sap) was obtained by enzymic ligation of six synthetic oligonucleotides. the 162 bp synthetic dna fragment was cloned into the c-terminal part of the lacz-gene employing the vector pur289. expression in e. coli in the presence of the inducer isopropylthiogalactoside (iptg) led to the formation of a fusion protein, which was shown by immuno-blotting to contain immuno-reactive antimicrobial protein. approxim ...19873304335
production of monospecific antibodies to a low-abundance hepatic membrane protein using nitrocellulose immobilized protein as antigen.membrane proteins from primary cultures of rat hepatocytes were separated by two-dimensional polyacrylamide gel electrophoresis. the proteins were transferred to nitrocellulose paper which was then dissolved in dimethyl sulfoxide and this mixture was used as a primary immunogen in rabbits. subsequent immunizations were performed using nonsolubilized protein immobilized on nitrocellulose paper. a monospecific polyclonal antibody was generated against a specific mitochondrial membrane protein (mp- ...19873304007
retardation of cell cycle progression in yeast cells recovering from dna damage: a study at the single cell level.pedigree analyses of individual yeast cells recovering from dna damage were performed and time intervals between morphological landmark events during the cell cycle (bud emergence and cell separation), were recorded for three generations. the associated nuclear behavior was monitored with the aid of dapi staining. the following observations were made: all agents tested (x-rays, mms, ems, mnng, nitrous acid) delayed the first bud emergence after treatment, which indicates inhibition of the initia ...19873302599
[the men behind the syndrome: johannes peutz and harold jeghers. the explorers of an underdiagnosed condition with intestinal polyps and mucocutaneous pigmentations]. 20123302567
transition to flight nursing: three experiences. 20123302460
shigellosis in bangladesh: a reply. 19873302055
clinical presentation of shigellosis during the 1984 epidemic of bacillary dysentery in west bengal. 19873301795
treatment of bacillary dysentery: a comparison between enoxacin and nalidixic acid.a prospective randomized study has been conducted in rwanda to compare the efficacy of enoxacin versus nalidixic acid for the treatment of bacillary dysentery in adults. seventeen patients received nalidixic acid and 21 received enoxacin. all isolates (37 shigella, 1 campylobacter) were sensitive in vitro to the two drugs. all patients showed a favourable clinical and bacteriological response and the results obtained with both drugs were comparable. enoxacin seems to be a good alternative to nal ...19873301783
[reye-like syndrome due to shigella flexneri in a child]. 19873301584
ultrastructural study on the bacterial symbiont in giardia lamblia. 19863300600
live dysentery vaccine "vadizen" (t32-istrati) immunogenicity against shigella-like challenge in animals. 19863300598
corneal ulcer caused by shigella flexneri in an infant. 19873300355
multiple enteric pathogens in a patient with diarrhoea.a woman who recently arrived in canada from india developed a febrile, diarrhoeal illness. stool culture revealed the presence of salmonella typhi, campylobacter fetus subspecies jejuni and shigella flexneri. concurrent infection with these three pathogens does not appear to have been previously reported. the possibility of multiple pathogens should be considered in travellers who fail to respond to treatment of a single organism.19873299934
childhood cancer.the literature generally supports the evolving recognition that childhood cancers are influenced by the environment. this article discusses specific childhood cancers in regard to paternal and maternal occupation.20123299786
comparative bio-availability of theophylline whole and halved sustained-release tablets.in a randomised, multiple-dose, cross-over study in 14 healthy volunteers, plasma theophylline concentrations were compared during a 12-hour dosing interval after repeated administration of theophylline (euphyllin retard; byk gulden) as whole and halved tablets. bio-availability of theophylline from the halved tablets relative to the whole tablets was: 116% (100%, 134%) for the extent of absorption as judged by the area under the concentration time curve (auc) and 115% (99%, 135%) for the rate o ...20123299763
[growth and development of a population of the causative agent during an infection]. 19873299739
erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation.the avian acute leukemia virus e26 induces a mixed erythroid-myeloid leukemia in chickens and carries two distinct oncogenes, v-myb and v-ets. recently, a novel gene named erg, closely related to the v-ets oncogene, was identified in human colo 320 cells and the nucleotide sequence of its approximately 5.0-kilobase transcript, erg 1 was determined. in the present study, the nucleotide sequence of the alternatively spliced transcript, erg 2, was found to differ from erg 1 by a splicing event that ...19873299708
the protein subunits of the double-stranded rna dependent rna polymerase and methyltransferase of the cytoplasmic polyhedrosis virus of silkworm, bombyx mori.the particles of cpv of silkworm contain double-stranded rna polymerase and methyltransferase. it was reported in a previous paper that the genome-enzyme complex could be isolated. the genome-enzyme complex shows high enzyme activity of rna polymerase and methyltransferase in spite of the fact that it consists of only 5 percent of the protein. in order to clarify the protein subunits of the rna polymerase and methyltransferase, two methods were adopted. the sds-polyacrylamide gel electrophoretog ...19863299695
[diagnosis, prevention and treatment of drug allergy]. 20123299343
rubens peale and his spectacles. 20123298707
epinephrine, glucose, and lactate infusion in exercising adrenodemedullated rats.the purpose of this study was to determine the metabolic function of the marked increase in plasma epinephrine which occurs in fasted rats during treadmill exercise. fasted adrenodemedullated (adm) and sham-operated (sham) rats were run on a rodent treadmill (21 m/min, 15% grade) for 30 min or until exhaustion. adm rats were infused with saline, epinephrine, glucose, or lactate during the exercise bouts. adm saline-infused rats showed markedly reduced endurance, hypoglycemia, elevated plasma ins ...19873298192
examination by ultrasound of legg-calvé-perthes disease.eleven patients with legg-calvé-perthes disease (lcp) were examined ultrasonographically for their femoral head deformity. the outline of the cartilaginous femoral head was well demonstrated, and the image obtained corresponded to that observed by arthrography. using ultrasonography, a simple method was developed to determine the rate of deformity due to lcp. ultrasonography does not have the hazards of x-ray and is useful for the diagnosis of lcp.20113297450
examination by ultrasound of legg-calvé-perthes disease.eleven patients with legg-calvé-perthes disease (lcp) were examined ultrasonographically for their femoral head deformity. the outline of the cartilaginous femoral head was well demonstrated, and the image obtained corresponded to that observed by arthrography. using ultrasonography, a simple method was developed to determine the rate of deformity due to lcp. ultrasonography does not have the hazards of x-ray and is useful for the diagnosis of lcp.20113297450
behavior of beta 2-microglobulin in patients with chronic renal failure undergoing hemodialysis, hemodiafiltration and continuous ambulatory peritoneal dialysis (capd).beta 2-microglobulin (beta 2-m) is the major component of a new form of amyloid deposit found in carpal tunnel syndrome and dialysis arthropathy of long-term hemodialysis patients. in 52 patients on maintenance hemodialysis, serum beta 2-m concentration was elevated to 37.9 +/- 1.4 (normal 1.2 +/- 0.6) mg/l. it was correlated with the time on hemodialysis (r = 0.43, p less than 0.01) and was inversely correlated with residual renal function (r = 0.87, p less than 0.001). in 20 patients on capd, ...20123297439
humoral response in mice immunized with outer membrane proteins of shigella flexneri.intraperitoneal immunization of mice with outer membrane proteins (omp) of sh. flexneri induced in the animals a synthesis of specific antibodies. their level determined by elisa test was found to be relatively low in the sera of animals immunized with a single dose (10 micrograms) of omp; it was markedly higher in mice immunized with two doses of omp, and very high after three fold immunization. the specific antibodies maintained in the animals for 8-16 weeks after immunization. anti-omp sera g ...19863296993
[gardnerella vaginalis in nonspecific vaginitis]. 19873296818
[dynamics of bacterial polysensitization in acute dysentery in children depending on the species of the causative agent].studies on polysensitization, evaluated by the neutrophil damage index, have been made with the use of dysenterin and the allergens of hemolytic staphylococci, enterococci and escherichia coli. the studies have revealed that both specific and nonspecific sensitization to hemolytic staphylococci and enterococci is higher in dysentery caused by shigella flexneri than in dysentery caused by s. sonnei and has the tendency to increase in the course of the disease.19873296580
toxic megacolon complicating shigellosis. 19873295219
bacterial invasion of fibroblasts induces interferon production.although bacteria and/or bacterial products have been shown to induce interferon (ifn) production in cells of the immune system, the ability of non-lymphoid cells to produce ifn in response to bacterial products and/or bacterial invasion is currently unknown. in this study we examined murine and human fibroblasts for their ability to produce ifn in response to challenge with the invasive bacteria shigella flexneri and enteroinvasive escherichia coli. both human and murine primary cell cultures p ...19873295042
an accessory protein identical to mouse egasyn is complexed with rat microsomal beta-glucuronidase and is identical to rat esterase-3.we report biochemical, immunological, and genetic studies which demonstrate that an accessory protein with the essential features of mouse egasyn is complexed with and stabilizes a portion of beta-glucuronidase in microsomes of rat liver. the accessory protein exists as a complex with beta-glucuronidase since it coprecipitates with beta-glucuronidase after treatment of extracts with a specific beta-glucuronidase antibody. the two proteins are associated by noncovalent bonds since they are easily ...19873294829
an aminoacyl-trna synthetase complex in escherichia coli.aminoacyl-trna synthetases from several strains of escherichia coli are shown to elute as a high-molecular-weight complex on 6% agarose columns (bio-gel a-5m). in contrast, very little synthetase activity was observed in such complexes on sephadex g-200 columns, suggesting that these enzymes may interact with or are dissociated during chromatography on dextran. the size of the complex observed on bio-gel a-5m was influenced by the method of cell breakage and the salt concentrations present in bu ...19873294804
molecular cloning of invasion plasmid antigen (ipa) genes from shigella flexneri: analysis of ipa gene products and genetic mapping.tn5-tagged invasion plasmid dna (pwr110) from shigella flexneri serotype 5 (strain m90t) was cloned into the expression vector lambda gt11. recombinant phage (lambda gt11sfl) expressing pwr110-encoded polypeptide antigens were identified by using rabbit antisera directed against s. flexneri m90t invasion plasmid antigens. antigens encoded by lambda gt11sfl recombinant phage were characterized by reacting affinity-purified antibodies, eluted from nitrocellulose-bound plaques of lambda gt11sfl rec ...19873294797
effects of marine mammal parasites on human health. 19873294653
[technic of the peroperative use of doppler in neurosurgery].intraoperative doppler exploration during neurosurgery was used during treatment of intracranial aneurysms, arteriovenous malformations (avm) and cerebral revascularization by extra-intra cranial anastomosis (eica). it was also employed to study behavior of cortical arteries under different conditions. during treatment of aneurysms, doppler can show, prior to clipping, whether blood flow through. the flow is regular--spasm of supply artery provokes acceleration of blood rate. after clipping it i ...20053294324
demetrio sodi-pallares: the man and his thought. 19883293862
nonsteroidal anti-inflammatory drugs, and hypertension. 20093293496
hormonal abnormalities in obesity.we have found a number of interesting hormonal abnormalities in obese men and women: 1) obese women have normal levels of estrone, total estradiol, and total testosterone, but as a consequence of their subnormal levels of shbg, their levels of free estradiol and free testosterone are significantly elevated. 2) massive weight loss in obese women (to still elevated weight) results in normalization of the previously elevated free estradiol and free testosterone. 3) obese women have normal plasma dh ...20113293358
hormonal abnormalities in obesity.we have found a number of interesting hormonal abnormalities in obese men and women: 1) obese women have normal levels of estrone, total estradiol, and total testosterone, but as a consequence of their subnormal levels of shbg, their levels of free estradiol and free testosterone are significantly elevated. 2) massive weight loss in obese women (to still elevated weight) results in normalization of the previously elevated free estradiol and free testosterone. 3) obese women have normal plasma dh ...20113293358
redressing the balance. 20123292931
salmonellal mycotic abdominal-aortic aneurysm.a patient is described with a mycotic abdominal-aortic aneurysm that was caused by salmonella typhimurium, who presented to hospital four months after a urinary-tract infection that was caused by the same organism. the urinary-tract infection may have resulted from an episode of transient salmonellal bacteraemia, the significance of which was not appreciated. the pathogenesis, clinical features, treatment and prognosis of arteritis due to salmonella species are reviewed. the early diagnosis and ...19883292882
salmonellal mycotic abdominal-aortic aneurysm.a patient is described with a mycotic abdominal-aortic aneurysm that was caused by salmonella typhimurium, who presented to hospital four months after a urinary-tract infection that was caused by the same organism. the urinary-tract infection may have resulted from an episode of transient salmonellal bacteraemia, the significance of which was not appreciated. the pathogenesis, clinical features, treatment and prognosis of arteritis due to salmonella species are reviewed. the early diagnosis and ...19883292882
nonunion of intercondylar eminence fracture of the tibia.an unusual case of symptomatic nonunion of an intercondylar eminence fracture in an adult is presented. the nonunion was successfully treated using internal fixation and bone grafting.20093290508
suggestion to supplement shigella flexneri classification scheme with the subserovar shigella flexneri 4c: phenotypic characteristics of strains.a new serovar of shigella flexneri has been isolated with increasing frequency in the ussr. it has the antigenic formula iv:7,8. we suggest that it be incorporated into the classification scheme as s. flexneri subserovar 4c. the 212 strains of this proposed subserovar examined to date display biochemical and serological properties typical of the species, are sensitive to the genus-specific bacteriophage, and cause keratoconjunctivitis in the sereny test.19883290245
ifosfamide and vp-16213 combination chemotherapy combined with ablative chemotherapy and autologous marrow transplantation as salvage treatment for malignant lymphoma.eighteen patients with high-grade malignant lymphoma were treated with ifosfamide-vp16213 combinations after failing to respond completely or after relapsing on chop-like therapy. responders to the salvage therapy were subsequently treated with ablative chemotherapy (bcnu, vp-16213, ara-c and melfalan) and autografted. of these 18 patients six were in relapse, six were partial responders and six failed chop-like therapy. there were two complete remissions and seven partial responses to the ifosf ...20113289942
[changes in the degree of sensitivity to antibiotics of shigella isolated from patients with dysentery in a city infectious disease hospital over the past 8 years].changes in sensitivity of shigella and in particular shigella flexneri isolated from dysentery patients in a city infection hospital within 8 years i.e. from 1977 to 1985 were followed. it was shown that the changes were to the greater extent connected with preferable use of certain antibiotics in the hospital.19883288150
muscular contraction. 20123288085
[clinico-immunological characteristics of mixed intestinal infections in children]. 19883287323
conservation of an atp-binding domain among reca proteins from proteus vulgaris, erwinia carotovora, shigella flexneri, and escherichia coli k-12 and b/r.the purified reca proteins encoded by the cloned genes from proteus vulgaris, erwinia carotovora, shigella flexneri, and escherichia coli b/r were compared with the reca protein from e. coli k-12. each of the proteins hydrolyzed atp in the presence of single-stranded dna, and each was covalently modified with the photoaffinity atp analog 8-azidoadenosine 5'-triphosphate (8n3atp). two-dimensional tryptic maps of the four heterologous reca proteins demonstrated considerable structural conservation ...19883286605
chiasmal compression caused by a catheter in the suprasellar cistern. 20093285696
serum antibodies to lipopolysaccharide and natural immunity to shigellosis in an israeli military population. 19883283258
reaction of anti-hla-b monoclonal antibodies with envelope proteins of shigella species. evidence for molecular mimicry in the spondyloarthropathies.immunologic cross-reactivity between enteric bacteria and the hla-b27 protein may play a role in the etiology of reiter's syndrome and reactive arthritis. the reactivity of two anti-b27 mab (b27m1 and b27m2) with envelope proteins of shigella flexneri isolated from reiter's syndrome patients was studied by western blot analysis. proteins with an apparent mr of approximately 36 and 23 kda reacted with both mab in ascites. mab against related hla class i ag b7 and b40 did not react with the 23 kda ...19883283236
cardiac nuclear medicine, present status, future hopes as seen from the view of a cardiologist.the present techniques of nuclear medicine that are used in cardiology are critically evaluated. they are used mainly for the assessment of coronary circulation (measurement of regional flow and perfusion), on the determination of left ventricular muscle function (radionuclear ventriculography) and on the study of cardiac metabolism. the last-mentioned technique is unique insofar as (except for magnetic resonance imaging) there is no other method available to analyse myocardial metabolism noninv ...19883282883
[electrical activity of the heart atria]. 20123282619
quality of commercially produced shigella serogrouping and serotyping antisera.shigella grouping antisera from five manufacturers and typing antisera from two were purchased and evaluated with homologous and heterologous shigella strains in the slide agglutination test. only 31 of 73 (42%) antisera were satisfactory. in many instances, the antisera gave negative, as opposed to weak, reactions when they should have given strong positive reactions. four reagents cross-reacted with shigella strains. of the 19 polyvalent grouping antisera to subgroups shigella dysenteriae sero ...19883281972
abdominal pregnancy: current concepts of management.nine cases of early and six cases of advanced abdominal pregnancy managed at the university of mississippi medical center over a 20-year period are reviewed. an incidence of one abdominal pregnancy in 4857 deliveries occurred in this series. a perinatal mortality rate of 83% and no maternal mortality were noted, in contrast to published rates of 40-95% and 0.5-18%, respectively. important current concepts of management include difficulty in diagnosis, predisposing risk factors, suggestive signs ...20123281075
richard bright, pioneer epileptologist. 20123281059
toxoplasmosis and the acquired immune deficiency syndrome.the literature on toxoplasmosis in the acquired immune deficiency syndrome is reviewed with reference to more than 140 cases from various centres. the incidence, pathogenesis, clinical features, diagnosis, treatment and prognosis are considered.19883280690
[therapy of rheumatic disease of the future. a critical review of trends and new developments]. 20123280449
protein binding sites on escherichia coli 16s ribosomal rna; rna regions that are protected by proteins s7, s9 and s19, and by proteins s8, s15 and s17.selected groups of isolated 14c-labelled proteins from e. coli 30s ribosomal subunits were reconstituted with 32p-labelled 16s rna, and the reconstituted complexes were partially digested with ribonuclease a. rna fragments protected by the proteins were separated by gel electrophoresis and subjected to sequence analysis. complexes containing proteins s7 and s19 protected an rna region comprising helices 29 to 32, part of helix 41, and helices 42 and 43 of the 16s rna secondary structure. additio ...19883279390
combined parenteral and oral immunization results in an enhanced mucosal immunoglobulin a response to shigella flexneri.achieving a vigorous secretory immunoglobulin a (iga) response in intestinal secretions usually requires multiple doses of antigen given orally, while systemic immunity is more easily attained by parenteral immunization. this study examines the role of combined parenteral and oral immunizations to enhance the early mucosal immune response to an enteropathogen. we have used a chronically isolated intestinal-loop model in rabbits as a probe to monitor kinetically the initial (primary) local immune ...19883278985
a basic replicon of virulence-associated plasmids of shigella spp. and enteroinvasive escherichia coli is homologous with a basic replicon in plasmids of incf groups.shigella species and enteroinvasive escherichia coli strains carry a large (120- to 140-megadalton) plasmid called pinv, which contains genes essential for the invasiveness of these pathogens. hybridization with specific probes derived from the repfic and repfib replicons of the incf1 ent plasmid p307 showed that pinvs present in 35 clinical isolates are homologous with repfic but not repfib, regardless of the serogroup of the shigella or e. coli strain. repfic of p307, in turn, is very similar ...19883278983
pulmonary embolism. part ii. management. 20113278644
epidemiological aspects of studying outcome in rheumatoid arthritis.knowledge of the outcome of rheumatoid arthritis (ra) is important both to the patient and to the rheumatologist. however, little data exist on the long-term outcome and effects of treatment on the disease. consideration is given to the problems that arise in the choice of methods and measures to be used in an outcome study. patient selection is an underestimated factor, which often produces biases and problems of comparability. useful lessons can be learnt from examining outcome studies in othe ...20113277685
epidemiological aspects of studying outcome in rheumatoid arthritis.knowledge of the outcome of rheumatoid arthritis (ra) is important both to the patient and to the rheumatologist. however, little data exist on the long-term outcome and effects of treatment on the disease. consideration is given to the problems that arise in the choice of methods and measures to be used in an outcome study. patient selection is an underestimated factor, which often produces biases and problems of comparability. useful lessons can be learnt from examining outcome studies in othe ...20113277685
shigella bacteremia. 19883277577
experimental portal fibrosis produced by intraportal injection of killed nonpathogenic escherichia coli in rabbits.an attempt was made to develop an animal model for the study of the etiology of noncirrhotic portal fibrosis or idiopathic portal hypertension based on the assumption that it is related to chronic abdominal infection. rabbits were given killed nonpathogenic escherichia coli intraportally or intravenously. the animals to which a mixture of killed e. coli and rabbit antiserum (aggregated e. coli) was given intraportally developed remarkable histologic changes in the liver. the early inflammatory r ...19883276575
contamination of freshly slaughtered pig carcasses with human pathogenic yersinia enterocolitica.evidence is presented for the extent of contamination of freshly slaughtered pig carscasses with human pathogenic yersinia enterocolitica and shows the significance of faecal contamination as a source of infection. swab samples collected from the rectum and the surface of a total of 1458 pig carcasses were examined for the presence of human pathogenic y. enterocolitica. y. enterocolitica, biovar iv, serogroup 0:3, were isolated from the rectum of 360 pigs (24.7%). the organism was isolated from ...19883275322
salvage of the exposed breast implant.exposure of silicone breast implants may occur as a result of hematoma and infection, inadequate soft tissue coverage, use of steroids, or trauma. in various series the incidence of severe complications is reported to range from 1% to 4%. when exposure of the implant has occurred, most authors recommend removal with replacement four to six months later. in 11 patients we successfully salvaged the exposed breast implant. the technique was initially presented in 5 patients in 1974. successful salv ...20123273018
corrective methods for class ii patients. 20123272961
color drawings: a means of identifying problems in children.between the ages of seven and nine years, the child develops a schema or way to draw his version of the world. drawings are revealing in that they can help assess a child's behavior. figure drawings are useful in determining general cognitive development, self-image, and level of maturity (harris, 1963; dileo, 1973; dileo, 1983; and koppitz, 1968). as the child progresses through developmental stages in perceiving and using color, she similarly progresses in her drawing abilities. distinction, i ...20123272927
[attempts at limiting necrotic areas in acute myocardial infarction by intravenous infusion of dipyridamole]. 20123271275
the structure of te(oh)6.na3p3o9.k3p3o9.the structure of this compound, originally described in space group c2/c [averbuch-pouchot & durif (1987). acta cryst. c43, 1653-1655] is properly described as rhombohedral, space group r3c, with a = 12.355 (4) a, a = 51.01 (2) degrees, z = 2. (hexagonal cell: a = 10.640 (4), c = 32.16 (2) a, z = 6). revised coordinates are given.20123271075
structure of 6-dodecyl-2-methoxy-1,4-benzoquinone, a new synthetic contact allergen.c19h30o3, mr = 306.45, triclinic, p-1, a = 5.453 (1), b = 5.608 (1), c = 30.129 (2) a, alpha = 85.85 (1), beta = 88.66 (1), gamma = 83.02 (1) degree, v = 912.0 (1) a3, z = 2, dx = 1.116 mg m-3, cu k alpha radiation, lambda = 1.5418 a, mu = 0.548 mm-1, f(000) = 336, t = 296 k, r is 0.040 for 2489 observed unique reflections. the aliphatic side chain is slightly rotated from the quinone ring. the angle between the quinone-ring plane and the mean dodecyl-chain plane is 20.8 (2) degrees. the average ...20123271072
healthy nutrition. preventing nutrition-related diseases in europe. 20123270512
clinical spectrum of primary empty sella turcica.over recent years empty sella turcica has become more frequently diagnosed with high resolution computerized tomography and the associated clinical abnormalities have been better described. in this article the spectrum of clinical presentation is based on a review of 26 cases with six illustrative case reports. recommendations for management and further assessment are presented. it is important for clinicians to be aware of the varying presentations of this syndrome, since it should not be consi ...20123270319
[the method for collection of data on dental health among adults in skien]. 20113270026
electrophysiologic effects of aspirin on myocardium: interaction with catecholamine. 19883269682
electrophysiologic effects of aspirin on myocardium: interaction with catecholamine. 19883269682
cervical cord extradural haematoma with familial cutaneous haemangiomas.this case report confirms the link between familial cutaneous haemangiomas and haemangiomas of the spinal extradural space. haemorrhage from a cervical extradural haemangioma may cause a haematoma resulting in an anterior cord syndrome. recovery is possible with early diagnosis and surgical decompression at the involved level. if the diagnosis is not made the patient may die from this extradural cervical compression. diagnosis involves myelography with spinal angiography to confirm the site and ...20113267309
ionic basis of receptor potential of frog taste cells induced by acid stimuli.1. the ionic mechanism underlying the receptor potential in frog taste cells induced by acid stimuli was studied with single microelectrodes by replacing superficial and interstitial fluids of the tongue with modified saline solutions. 2. the removal of na+, ca2+ and cl- from the normal interstitial fluid did not affect the receptor potential induced by acid stimuli. interstitial 100 mm-k+ saline did not affect the acid response. 3. the receptor potential was reduced greatly when ca2+ was remove ...20113267156
elastic properties of relaxed, activated, and rigor muscle fibers measured with microsecond resolution.tension responses due to small and rapid length changes (completed within 40 microseconds) were obtained from skinned single-fiber segments (4- to 7-mm length) of the iliofibularis muscle of the frog incubated in relaxing, rigor, and activating solution. the fibers were skinned by freeze-drying. the first 500 microseconds of the responses for all three conditions could be described with a linear model, in which the fiber is regarded as a rod composed of infinitesimally small identical segments, ...20123266558
early and late complications of endoscopic oesophageal varices sclerotherapy.we report the complications of perendoscopic sclerotherapy observed during treatment of oesophageal varices in 104 patients and 409 sclerotherapy sessions. complications were related to each individual session and to the aim of the treatment (therapeutic or prophylactic). major complications occurred in 17.3% of the patients treated: 13 cases of severe bleeding and 5 of oesophageal stricture. conservative therapy stopped haemorrhage in all but 4 patients, who died of uncontrolled bleeding (3.8%) ...20123266535
cultural construction of the menopausal syndrome: the japanese case.europe and north america have been the focus of most research on the menopause and its symptoms. in this study, in the course of in-depth interviews japanese physicians and women were asked to describe the menopausal experience. a cross-sectional survey concerning women and their health at midlife was then distributed to 1738 women. the analysis in this paper is based on the replies received from 1141 non-hysterectomized women aged 45-55. factor analysis was used to group the symptoms these wome ...20113265758
[incidence of ischemic heart disease in relation to major risk factors among moscow male residents aged 20-29 years].a representative random sample of 3,308 male residents aged 20-59 years from a moscow district was examined. only 74% of them participated in the study. routine epidemiological methods were used to identify various forms of coronary heart disease (chd). the prevalence of chd was 9.7% in the population with the incidence of definite chd of 5% and possible chd of 4.6%. the prevalence of chd was significantly associated with age, arterial hypertension, hypercholesterolemia, hypertriglyceridemia, hy ...20123265747
the 28-kda/32-kda activation antigen ea 1. further characterization and signal requirements for its expression.the tumor promoter pma has been shown to induce the expression of a 28-kda/32-kda early activation ag, termed ea 1, on resting t cells. under nonreducing conditions, ea 1 was detected by sds-page as a diffuse band in the 60-kda region. in this study, this diffuse band was resolved into 56-kda and 60-kda bands. endoglycosidase f treatment of ea 1 resulted in the appearance of a single band with a mr of 48 kda. upon reduction, the 48-kda band was shown to be composed of 24-kda peptides. diagonal g ...20123264302
human cryptosporidiosis in north queensland.during a 12-month period, feces from 780 persons from the townsville region were evaluated by the kinyoun acid-fast strain, and 36 (4.6%) immunocompetent patients were found to have cryptosporidium oocysts. twenty-five index cases were identified; 13 (8.6%) cases from 151 patients were from palm island, an isolated aboriginal community in the wet tropics and 12 (1.9%) cases from 629 patients were from the dry tropics of townsville. all 11 secondary cases were associated with a person-to-person o ...19883264149
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