Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| systematic analysis of the ssrab virulon of salmonella enterica. | intracellular salmonella enterica serovar typhimurium deploys the salmonella pathogenicity island 2 (spi2)-encoded type iii secretion system (t3ss) to modify host cell functions and accomplish intracellular replication. this virulence function is controlled by the two-component system ssrab that regulates the expression of several operons in spi2 and, in addition, a large number of genes for non-spi2-encoded effector proteins. here, we analyzed the relative expression levels of members of the ss ... | 2010 | 19858298 |
| ctx-m-2-producing salmonella typhimurium isolated from pediatric patients and poultry in brazil. | ten salmonella enterica serovar typhimurium isolates producing ctx-m-2 extended-spectrum beta-lactamase were identified from clinical and poultry sources in two distant cities in brazil between 2003 and 2004. they included two isolates from pediatric patients and eight isolates from poultry or its environment. all isolates exhibited coresistance to non-beta-lactam antimicrobials including tetracycline and trimethoprim/sulfamethoxazole. the ctx-m-2 gene was located on transferable plasmids with s ... | 2009 | 19857139 |
| molecular epidemiology and genetic environment of acquired bla acc-1 in salmonella enterica serotype livingstone causing a large nosocomial outbreak in tunisia. | eighty-four isolates of salmonella enterica serovar livingstone were collected from patients hospitalized in a pediatric ward in sfax hospital (south tunisia). these isolates were responsible for two nosocomial outbreaks in 2000 and 2002. twenty-eight clinical isolates of s. enterica serovar livingstone were also obtained in two other tunisian hospitals in monastir (central tunisia) and tunis (north tunisia), respectively, in 2002 and 2003. pulsed-field gel electrophoresis yielded that these iso ... | 2009 | 19857134 |
| infected abdominal aortic aneurysm caused by nontyphoid salmonella in an immunocompromised patient with rheumatoid arthritis. | nontyphoid salmonella strains are important pathogens commonly found worldwide, typically causing gastrointestinal illness. here, we report a case of a 66-yearold man with an abdominal aortic infected (or so-called mycotic) aneurysm caused by salmonella enterica subsp. enterica serovar enteritidis (s. enteritidis). he had multiple risk factors for atherosclerosis: age over 60, a long history of smoking, an 8-year history of diabetes mellitus, and a 10-year history of rheumatoid arthritis treated ... | 2009 | 19856069 |
| phage therapy to reduce preprocessing salmonella infections in market-weight swine. | contamination of meat products with food-borne pathogens usually results from the carcass coming in contact with the feces of an infected animal during processing. in the case of salmonella, pigs can become colonized with the organism during transport and lairage from contaminated trailers and holding pens, resulting in increased pathogen shedding just prior to processing. increased shedding, in turn, amplifies the likelihood of carcass contamination by magnifying the amount of bacteria that ent ... | 2010 | 19854929 |
| beta-lactam resistance in salmonella strains isolated from retail meats in the united states by the national antimicrobial resistance monitoring system between 2002 and 2006. | ampicillin-resistant (amp(r)) salmonella enterica isolates (n = 344) representing 32 serotypes isolated from retail meats from 2002 to 2006 were tested for susceptibility to 21 other antimicrobial agents and screened for the presence of five beta-lactamase gene families (bla(cmy), bla(tem), bla(shv), bla(oxa), and bla(ctx-m)) and class 1 integrons. among the amp(r) isolates, 66.9% were resistant to five or more antimicrobials and 4.9% were resistant to 10 or more antimicrobials. coresistance to ... | 2009 | 19854922 |
| evaluation of live-attenuated salmonella vaccines expressing campylobacter antigens for control of c. jejuni in poultry. | campylobacter jejuni is a zoonotic bacterial pathogen of worldwide importance. it is estimated that 460,000 human infections occur in the united kingdom per annum and these involve acute enteritis and may be complicated by severe systemic sequelae. such infections are frequently associated with the consumption of contaminated poultry meat and strategies to control c. jejuni in poultry are expected to limit pathogen entry into the food chain and the incidence of human disease. toward this aim, a ... | 2010 | 19853682 |
| phage-type specific markers identified by diversity arrays technology (dart) analysis of salmonella enterica ssp. enterica serovars enteritidis and typhimurium. | diversity arrays technology (dart) was applied to differentiate between s. enterica serovar enteritidis and typhimurium strains, respectively. ten and eleven, mainly phage and plasmid-related markers were identified for serovars enteritidis and typhimurium. in combination, these markers can be used for subtyping among and within phage types. | 2010 | 19852988 |
| effect of adjuvants on immune response and protective immunity elicited by recombinant hsp60 (groel) of salmonella typhi against s. typhi infection. | heat shock proteins (hsps) have been reported to be dominant antigens for the host immune response to various pathogens and thus, have great potential for use in vaccination. in the present study, we evaluated the immunogenicity and protective efficacy of groel of salmonella enterica serovar typhi against lethal infection by s. typhi ty2 in mice with or without adjuvants. anti groel-igg titers were significantly higher in mice immunized with either groel-alone or in combination with alum/complet ... | 2010 | 19851830 |
| identification and characterization of a novel antibacterial peptide, avian beta-defensin 2 from ducks. | in this study, a novel avian beta-defensin (avbd) was isolated from duck pancreas. the complete nucleotide sequence of the gene contained an 195 bp open reading frame encoding 64 amino acids. homology, characterization and comparison of the gene with avbd from other avian species confirmed that it was duck avbd2. the mrna expression of the gene was analyzed in 17 tissues from 21-day-old ducks. avbd2 was highly expressed in the trachea, crop, heart, bone marrow, and pancreas; moderately expressed ... | 2009 | 19851734 |
| diagnostic utility of a single widal test in the diagnosis of typhoid fever at aga khan university hospital (akuh), nairobi, kenya. | typhoid fever is a systemic illness caused by salmonella enterica serovar typhi (s. typhi) and is endemic in kenya, where a single widal test done on an acute phase serum is the most commonly used test. using a cut-off value of 1:320 for both o and h agglutinins as being diagnostic of s. typhi, only 18 (26%) of our patients had diagnostic titres; 37 (53.6%) had o and h titres less than 1:40. our study showed that widal testing done on an acute phase serum of a patient suspected to have typhoid f ... | 2010 | 19850607 |
| induction of cxc chemokine messenger-rna expression in chicken oviduct epithelial cells by salmonella enterica serovar enteritidis via the type three secretion system-1. | the messenger-rna (mrna) expression of selected cytokines and chemokines in primary chicken oviduct epithelial cells (coec) was determined following in vitro infections with wild-type or type three secretion system (t3ss)-mutant salmonella enterica serovar enteritidis (se) strains. all se strains examined in this study elicited the expression of proinflammatory immune mediators including inducible nitric oxide synthase (inos), cxcli1 (k60), cxcli2 (il-8), ccli3 (k203), and ccli4 (mip-1beta). se ... | 2009 | 19848079 |
| identification of salmonella enterica subspecies i, salmonella enterica serovars typhimurium, enteritidis and typhi using multiplex pcr. | this study was designed to develop a multiplex pcr method with five specific primer pairs for the detection of salmonella spp., salmonella subspecies i, salmonella enterica serovars typhimurium, typhi and enteritidis. a multiplex pcr was constructed with five primer pairs for the detection of salmonella and pathogenic salmonella serovars, including a specific primer pair for salmonella typhi, based on the sequence comparison between genomic dna sequences of 12 salmonella strains. each primer pai ... | 2009 | 19843307 |
| the synergistic activity of triclosan and ciprofloxacin on biofilms of salmonella typhimurium. | triclosan is a biocide whose wide use has raised a debate about the potential benefits vs. hazards of the incorporation of antimicrobials in consumer products. the purpose of the present study was to determine whether exposure of biofilms of salmonella enterica serovar typhimurium to triclosan influences the tolerance of the bacteria towards antibiotics such as ciprofloxacin and vice versa. a synergistic antibiofilm activity was observed when the biofilms were treated with triclosan before or to ... | 2009 | 19843306 |
| ndp52: the missing link between ubiquitinated bacteria and autophagy. | mammalian cells ubiquitinate bacteria that erroneously enter the cytosol and target these intruding microbes for destruction by autophagy. new work shows that the protein ndp52 directly binds to ubiquitinated bacteria and facilitates the assembly of an autophagic membrane that surrounds these invaders. | 2009 | 19841643 |
| multistate outbreak of salmonella infections associated with small turtle exposure, 2007-2008. | turtle-associated salmonellosis was increasingly recognized in the united states during the 1960s, leading to a federal ban in 1975 on the sale of turtles <4 inches in carapace length (small turtles). although sporadic reports of turtle-associated salmonella are frequent, outbreaks are rare. in september 2007, several patients with salmonella enterica serotype paratyphi b var java infections reported recent turtle exposure. we conducted an investigation to determine the source and extent of the ... | 2009 | 19841114 |
| supplement 2003-2007 (no. 47) to the white-kauffmann-le minor scheme. | this supplement reports the characterization of 70 new salmonella serovars recognized between 2003 and 2007 by the who collaborating center for reference and research on salmonella: 44 were assigned to salmonella enterica subspecies enterica, 11 to subspecies salamae, 5 to subspecies arizonae, 8 to subspecies diarizonae, one to subspecies houtenae and one to salmonella bongori. one new serovar, mygdal, displayed a new h factor, h:z(91). | 2010 | 19840847 |
| rpos- and crp-dependent transcriptional control of salmonella typhi taia and hlye genes: role of environmental conditions. | a novel pathogenicity island, spi-18, carries the taia-hlye operon, encoding virulence factors in salmonella typhi. to determine the effects of certain environmental conditions on the expression of these genes, beta-galactosidase assays, rt-pcr reactions, western blot analyses and measurement of hemolytic activity were performed. the conditions studied are those likely found by s. typhi during infection in the human host. we found rpos-dependent transcriptional upregulation in low ph and high os ... | 2009 | 19835951 |
| comparative analysis of acid resistance in listeria monocytogenes and salmonella enterica strains before and after exposure to poultry decontaminants. role of the glutamate decarboxylase (gad) system. | data on the ability of chemical poultry decontaminants to induce an acid stress response in pathogenic bacteria are lacking. this study was undertaken in order to compare the survival rates in acid broths of listeria monocytogenes and salmonella enterica strains, both exposed to and not exposed to decontaminants. the contribution of the glutamate decarboxylase (gad) acid resistance system to the survival of bacteria in acid media was also examined. four strains (l. monocytogenes serovar 1/2, l. ... | 2009 | 19835779 |
| effect of x-ray treatments on inoculated escherichia coli o157: h7, salmonella enterica, shigella flexneri and vibrio parahaemolyticus in ready-to-eat shrimp. | this study was conducted to evaluate the inactivation effect of x-ray treatments on escherichia coli o157: h7, salmonella enteric (s. enterica), shigella flexneri (s. flexneri) and vibrio parahaemolyticus (v. parahaemolyticus) artificially inoculated in ready-to-eat (rte) shrimp. a mixed culture of three strains of each tested pathogen was used to inoculate rte shrimp. the shrimp samples were inoculated individually with selected pathogenic bacteria then aseptically placed in sterile plastic cup ... | 2009 | 19835772 |
| myo-inositol transport by salmonella enterica serovar typhimurium. | in salmonella enterica serovar typhimurium, the genomic island gei4417/4436 has recently been identified to be responsible for myo-inositol (mi) utilization. here, two of the four island-encoded permeases are identified as the mi transporters of this pathogen. in-frame deletion of iolt1 (stm4418) led to a severe growth defect, and deletion of iolt1 (stm4419) to a slight growth defect in the presence of mi. these phenotypes could be complemented by providing the putative transporter genes in tran ... | 2010 | 19833776 |
| development of an oligonucleotide-based microarray to detect multiple foodborne pathogens. | escherichia coli o157:h7, salmonella enterica, listeria monocytogenes and campylobacter jejuni are considered important pathogens causing the most food-related human illnesses worldwide. current methods for pathogen detection have limitations in the effectiveness of identifying multiple foodborne pathogens. in this study, a pathogen detection microarray was developed using various 70-mer oligonucleotides specifically targeting the above pathogens. to reduce the cost of detection, each microarray ... | 2010 | 19833198 |
| changes of physiological and biochemical properties of salmonella enterica serovar typhimurium by deletion of cpxr and lon genes using allelic exchange method. | to construct a novel salmonella attenuated live vaccine, the cpxr and lon genes were deleted from a wild-type salmonella enterica serovar typhimurium (s. typhimurium) using allelic exchange method, resulting in s. typhimurium ck31 (deltacpxr), ck38 (deltalon), and ck111 (deltacpxr/lon). these mutated strains were grown normally, as was the wild-type strain. the biochemical properties of the mutants remained highly similar to those of the wild-type. in comparison with the wild-type, 1.5 to 3.3-fo ... | 2009 | 19833153 |
| a rapid screen of broth enrichments for salmonella enterica serovars enteritidis, hadar, heidelberg, and typhimurium by using an allelotyping multiplex pcr that targets o- and h-antigen alleles. | salmonella continues to cause significant foodborne outbreaks, best illustrated with recent outbreaks associated with peanut butter, raw tomatoes, and serrano peppers. to ascertain the likely source of the outbreak, bacterial typing is essential to this process. while pcr has become an important detection tool for pathogens in foods, pcr can also identify strain differences by targeting gene(s) or sequences exhibiting polymorphisms or variability in its distribution within the bacterial populati ... | 2009 | 19833046 |
| isolation of salmonella enterica in laying-hen flocks and assessment of eggshell contamination in france. | the present investigation was conducted in conjunction with the european union baseline study for the estimation of salmonella prevalence in laying-hen flocks. it aimed at evaluating eggshell contamination in farms positive for salmonella, characterizing the genetic patterns of salmonella strains and identifying the factors associated with salmonella contamination of eggshells. for this purpose, a total of 4,200 eggs were collected from 28 positive flocks and analyzed according to draft annex d ... | 2009 | 19833029 |
| simultaneous enrichment of shiga toxin-producing escherichia coli o157 and o26 and salmonella in food samples using universal preenrichment broth. | universal preenrichment broth (upb) was compared with modified escherichia coli broth with novobiocin (mec+n) for enrichment of shiga toxin-producing e. coli o157 and o26, and with buffered peptone water (bpw) for preenrichment of salmonella enterica. ten strains each of the three pathogens were inoculated into beef and radish sprouts following thermal, freezing, or no treatment. with regard to o157 and o26, upb incubated at 42 degrees c recovered significantly more cells from inoculated beef th ... | 2009 | 19833028 |
| [serovars of salmonella enterica subspecies enterica and its antimicrobial resistance in slaughterhouse pigs]. | a study was carried out in order to determine the prevalence of salmonella and its serovars among porcine slaughterhouses, to evaluate the antimicrobial resistance profiles and to know the presence of class 1 integrons as possible reservoir of resistance. from a total of 386 samples from four porcine slaughterhouses of buenos aires and santa fe provinces (argentina), 93 (24.1%) salmonella enterica subspecies enterica strains were identified, 52 (55.9%) from cecal contents and 41 (44.1%) from ile ... | 2009 | 19831314 |
| salmonella enterica serovar israel causing perforating appendicitis. | 2010 | 19828346 | |
| a novel inhibitor of chlamydophila pneumoniae protein kinase d (pknd) inhibits phosphorylation of cdsd and suppresses bacterial replication. | we have shown previously that chlamydophila pneumoniae contains a dual-specific ser/thr protein kinase that phosphorylates cdsd, a structural component of the type iii secretion apparatus. to further study the role of pknd in growth and development we sought to identify a pknd inhibitor to determine whether pknd activity is required for replication. | 2009 | 19828035 |
| simultaneous assay of every salmonella typhi gene using one million transposon mutants. | very high-throughput sequencing technologies need to be matched by high-throughput functional studies if we are to make full use of the current explosion in genome sequences. we have generated a very large bacterial mutant pool, consisting of an estimated 1.1 million transposon mutants and we have used genomic dna from this mutant pool, and illumina nucleotide sequencing to prime from the transposon and sequence into the adjacent target dna. with this method, which we have called tradis (transpo ... | 2009 | 19826075 |
| evidence for il-6 promoter nuclear activation in u937 cells stimulated with salmonella enterica serovar typhimurium porins. | interleukin-6 (il-6) is a pleiotropic cytokine and plays an active role in inflammatory and immune responses, contributing to a multitude of physiological and pathophysiological processes. in this study, we address the molecular mechanism of il-6 transcriptional induction and propose a correlation between activated nf-kappab localization and il-6 expression. in particular, we detected, by chip assay, that occupation of the il-6 gene promoter site is dependent on activated nf-kappab. in fact, aft ... | 2009 | 19825524 |
| antimicrobial resistance and virulence genes in salmonella enterica isolates from dairy cows. | one hundred sixty salmonella enterica isolates from clinically healthy dairy cows were assayed for antibiotic susceptibilities, the presence of class 1 integrons, antimicrobial resistance genes and virulence genes, and conjugal transfer of antimicrobial resistance determinants. one hundred nine (68%) of the salmonella isolates were resistant to at least 1 antibiotic, and 14 isolates (9%) were multiresistant. the most prevalent resistance observed was to streptomycin (64%). class 1 integrons were ... | 2010 | 19821743 |
| the tbk1 adaptor and autophagy receptor ndp52 restricts the proliferation of ubiquitin-coated bacteria. | cell-autonomous innate immune responses against bacteria attempting to colonize the cytosol of mammalian cells are incompletely understood. polyubiquitylated proteins can accumulate on the surface of such bacteria, and bacterial growth is restricted by tank-binding kinase (tbk1). here we show that ndp52, not previously known to contribute to innate immunity, recognizes ubiquitin-coated salmonella enterica in human cells and, by binding the adaptor proteins nap1 and sintbad, recruits tbk1. knockd ... | 2009 | 19820708 |
| characteristics and dynamics of salmonella contamination along the coast of agadir, morocco. | the occurrence of salmonella enterica in the environment of tropical and desert regions has remained largely uninvestigated in many areas of the world, including africa. in the present study, we investigated the presence of salmonella spp. along 122 km of the coastline of agadir (southern morocco) in relation to environmental parameters. a total of 801 samples of seawater (243), marine sediment (279), and mussels (279) were collected from six sites between july 2004 and may 2008. the overall pre ... | 2009 | 19820155 |
| salmonella enterica serovar typhimurium can detect acyl homoserine lactone production by yersinia enterocolitica in mice. | luxr-type transcription factors detect acyl homoserine lactones (ahls) and are typically used by bacteria to determine the population density of their own species. escherichia coli and salmonella enterica serovar typhimurium cannot synthesize ahls but can detect the ahls produced by other bacterial species using the luxr homolog, sdia. previously we determined that s. typhimurium did not detect ahls during transit through the gastrointestinal tract of a guinea pig, a rabbit, a cow, 5 mice, 6 pig ... | 2010 | 19820103 |
| ten years experience of salmonella infections in cambridge, uk. | review of all salmonella infections diagnosed in the cambridge area over 10 years. | 2010 | 19819256 |
| functional and molecular characterization of pse34 encoding a type iv secretion system in salmonella enterica serotype enteritidis phage type 34. | salmonella enterica serotype enteritidis infection remains a serious public health threat to humans. salmonella enteritidis phage type 4 (pt4) is a clone that has already caused a global pandemic for years. to investigate why pt34 becomes a subdominantly emerging phage type, molecular characterizations, including serotyping, pulsed-field gel electrophoresis (pfge), phage typing, and plasmid profiling, were carried out on pt34. the results indicated that relative to pt4, pt34 contained an additio ... | 2009 | 19817860 |
| a tdca mutation reduces the invasive ability of salmonella enterica serovar typhimurium. | we previously observed that the transcription of some flagellar genes decreased in salmonella typhimurium tdca mutant, which is a gene encoding the transcriptional activator of the tdc operon. since flagella-mediated bacterial motility accelerates the invasion of salmonella, we have examined the effect of tdca mutation on the invasive ability as well as the flagellar biosynthesis in s. typhimurium. a tdca mutation caused defects in motility and formation of flagellin protein, flic in s. typhimur ... | 2009 | 19812899 |
| overexpression, purification, and immunogenicity of recombinant porin proteins of salmonella enterica serovar typhi (s. typhi). | porin proteins of gram-negative bacteria are outer membrane proteins that act as receptors for bacteriophages and are involved in a variety of functions like solute transport, pathogenesis, and immunity. salmonella enterica serovar typhi (s. typhi), a gram-negative bacterium, is the causative agent of typhoid fever. porins of s. typhi have been shown to have a potential role in diagnostics and vaccination. in the present study, the major outer membrane proteins ompf and ompc from s. typhi were c ... | 2009 | 19809263 |
| identification of salmonella pullorum genomic sequences using suppression subtractive hybridization. | pullorum disease affecting poultry is caused by salmonella enterica serovar pullorum and results in severe economic loss every year, especially in countries with a developing poultry industry. the pathogenesis of s. pullorum is not yet well defined, as the specific virulence factors still need to be identified. thus, to isolate specific dna fragments belonging to s. pullorum, this study used suppression subtractive hybridization. as such, the genome of the s. pullorum c79-13 strain was subtracte ... | 2009 | 19809245 |
| m-01zh09, an oral live attenuated salmonella enterica serovar typhi vaccine for the prevention of typhoid fever. | typhoid fever remains a major health problem globally, particularly in the developing world. the increased emergence of several multidrug-resistant strains of salmonella enterica serovar typhi has made the management of the disease increasingly difficult. although vaccines against typhoid fever are available, improvements are desired in dosage, immunogenicity and tolerability. emergent biosolutions inc is developing m-01zh09, a single-dose oral vaccine against typhoid fever based on an attenuate ... | 2009 | 19806505 |
| changing trends in antimicrobial resistance of salmonella enterica serovar typhi and salmonella enterica serovar paratyphi a in chennai. | chloramphenicol was considered the anti-microbial gold standard for typhoid treatment but, following the increasing worldwide frequency of antibiotic resistance, ciprofloxacin has been the mainstay of therapy since 1980. recent studies have shown a shifting of susceptibility to conventional drugs like chloramphenicol, ampicillin and cotrimoxazole. the primary objective of the study was to evaluate the in vitro activity of chloramphenicol and other first-line drugs in comparison with cephalospori ... | 2009 | 19805957 |
| eradication of intracellular salmonella enterica serovar typhimurium with a small-molecule, host cell-directed agent. | eradication of intracellular pathogenic bacteria with host-directed chemical agents has been an anticipated innovation in the treatment of antibiotic-resistant bacteria. we previously synthesized and characterized a novel small-molecule agent, ar-12, that induces autophagy and inhibits the akt kinase in cancer cells. as both autophagy and the akt kinase have been shown recently to play roles in the intracellular survival of several intracellular bacteria, including salmonella enterica serovar ty ... | 2009 | 19805568 |
| regulated delayed expression of rfah in an attenuated salmonella enterica serovar typhimurium vaccine enhances immunogenicity of outer membrane proteins and a heterologous antigen. | rfah is a transcriptional antiterminator that reduces the polarity of long operons encoding secreted and surface-associated cell components of salmonella enterica serovar typhimurium, including o antigen and lipopolysaccharide core sugars. a deltarfah mutant strain is attenuated in mice (50% lethal dose [ld(50)], >10(8) cfu). to examine the potential for using rfah in conjunction with other attenuating mutations, we designed a series of strains in which we replaced the native rfah promoter with ... | 2009 | 19805538 |
| the long-lived nature of clostridium perfringens iota toxin in mammalian cells induces delayed apoptosis. | mono-adp ribosylation of actin by bacterial toxins, such as clostridium perfringens iota or clostridium botulinum c2 toxins, results in rapid depolymerization of actin filaments and cell rounding. here we report that treatment of african green monkey kidney (vero) cells with iota toxin resulted in delayed caspase-dependent death. unmodified actin did not reappear in toxin-treated cells, and enzyme-active toxin was detectable in the cytosol for at least 24 h. c2 toxin showed comparable, long-live ... | 2009 | 19805536 |
| increased expression of mg(2+) transport proteins enhances the survival of salmonella enterica at high temperature. | mg(2+) homeostasis is important for salmonella pathogenesis. in salmonella enterica, the transcription of the mgta gene, which encodes a mg(2+) transporter, is regulated by a mg(2+)-sensing riboswitch [cromie mj, shi y, latifi t, groisman ea (2006) cell 125:71-84]. in a genetic analysis of the determinants of thermotolerance in s. enterica serovar typhimurium, we isolated the chr-1 mutation that increased the resistance of exponential phase cells to killing by high temperature. this mutation is ... | 2009 | 19805196 |
| a coiled-coil motif that sequesters ions to the hydrophobic core. | most core residues of coiled coils are hydrophobic. occasional polar residues are thought to lower stability, but impart structural specificity. the coiled coils of trimeric autotransporter adhesins (taas) are conspicuous for their large number of polar residues in position d of the core, which often leads to their prediction as natively unstructured regions. the most frequent residue, asparagine (n@d), can occur in runs of up to 19 consecutive heptads, frequently in the motif [i/v]xxntxx. in th ... | 2009 | 19805097 |
| autophagy in immunity against intracellular bacteria. | autophagy is an innate immune defense mechanism against various intracellular bacterial pathogens, such as salmonella enterica serovar typhimurium (s. typhimurium), listeria monocytogenes and shigella flexneri. s. typhimurium uses type three secretion systems (t3sss) to invade mammalian cells and replicate in salmonella-containing vacuoles (scvs). a small population of intracellular s. typhimurium is targeted by autophagy shortly after infection. evidence suggests that these bacteria are present ... | 2009 | 19802566 |
| neonatal sepsis due to salmonella typhi and paratyphi a. | sepsis due to salmonella enterica serovar typhi and paratyphi a is rare in neonates. though described as a mild and unrecognized illness in infants, life-threatening complications and even deaths have been reported. we present five cases of neonatal septicaemia due to s. typhi and s. paratyphi a. the cases were presented because of their interesting clinical presentations and possible modes of transmission. salmonella infections should be considered in the differential diagnosis of sepsis neonat ... | 2009 | 19801808 |
| analysis of the variability in the number of viable bacteria after mild heat treatment of food. | variability in the numbers of bacteria remaining in saline solution and whole milk following mild heat treatment has been studied with listeria innocua, enterococcus faecalis, salmonella enterica serovar enteritidis, and pseudomonas fluorescens. as expected, the most heat-resistant bacterium was e. faecalis, while p. fluorescens was the least heat resistant, and all bacteria showed greater thermal resistance in whole milk than in saline solution. despite the differences in the inactivation kinet ... | 2009 | 19801476 |
| activated by different signals, the phop/phoq two-component system differentially regulates metal uptake. | the phop/phoq two-component system controls several physiological and virulence functions in salmonella enterica. this system is activated by low mg(2+), acidic ph, and antimicrobial peptides, but the biological consequences resulting from sensing multiple signals are presently unclear. here, we report that the phop/phoq system regulates different salmonella genes depending on whether the inducing signal is acidic ph or low mg(2+). when salmonella experiences acidic ph, the phop/phoq system prom ... | 2009 | 19801407 |
| emergence of multidrug-resistant salmonella enterica serovar typhi with reduced susceptibility to fluoroquinolones in cambodia. | from december 2006 to april 2009, we conducted an etiology study among cambodian patients presenting with acute fever of unknown origin. salmonella enterica serovar typhi was detected in 0.9% (41/4985) blood cultures. antimicrobial susceptibility testing showed decreased susceptibility to ampicillin (56% resistant; mic(90), >256 microg/ml), chloramphenicol (56% resistant; mic(90), >256 microg/ml), trimethoprim/sulfamethoxazole (56% resistant; mic(90), >256 microg/ml), nalidixic acid (81% resista ... | 2010 | 19800753 |
| seroprevalence of antibodies against salmonella enterica subsp. enterica serovar gallinarum-pullorum in wild doves (zenaida asiatica and zenaida macroura) from the northeast of mexico. | a cross-sectional survey was conducted in order to determine the seroprevalence and to identify some factors associated with the presence of antibodies against salmonella enterica subsp. enterica serovar gallinarum-pullorum in white-winged (zenaida asiatica) and mourning doves (zenaida macroura) from hunting areas of northeast mexico. from september to october 2006, 201 serum samples were analyzed with the seroagglutination test. the overall seroprevalence of s. enterica subsp. enterica serovar ... | 2010 | 19800701 |
| edible apple film wraps containing plant antimicrobials inactivate foodborne pathogens on meat and poultry products. | apple-based edible films containing plant antimicrobials were evaluated for their activity against pathogenic bacteria on meat and poultry products. salmonella enterica or e. coli o157:h7 (10(7) cfu/g) cultures were surface inoculated on chicken breasts and listeria monocytogenes (10(6) cfu/g) on ham. the inoculated products were then wrapped with edible films containing 3 concentrations (0.5%, 1.5%, and 3%) of cinnamaldehyde or carvacrol. following incubation at either 23 or 4 degrees c for 72 ... | 2009 | 19799671 |
| dsbl and dsbi contribute to periplasmic disulfide bond formation in salmonella enterica serovar typhimurium. | disulfide bond formation in periplasmic proteins is catalysed by the dsba/dsbb system in most gram-negative bacteria. salmonella enterica serovar typhimurium also encodes a paralogous pair of proteins to dsba and dsbb, dsbl and dsbi, respectively, downstream of a periplasmic arylsulfate sulfotransferase (asst). we show that dsbl and dsbi function as a redox pair contributing to periplasmic disulfide bond formation and, as such, affect transcription of the salmonella pathogenicity island 1 (spi1) ... | 2009 | 19797361 |
| superior protective immunity against murine listeriosis by combined vaccination with cpg dna and recombinant salmonella enterica serovar typhimurium. | preexisting antivector immunity can severely compromise the ability of salmonella enterica serovar typhimurium live vaccines to induce protective cd8 t-cell frequencies after type iii secretion system-mediated heterologous protein translocation in orally immunized mice. to circumvent this problem, we injected cpg dna admixed to the immunodominant p60(217-225) peptide from listeria monocytogenes subcutaneously into balb/c mice and coadministered a p60-translocating salmonella strain by the orogas ... | 2009 | 19797070 |
| effect of the o-antigen length of lipopolysaccharide on the functions of type iii secretion systems in salmonella enterica. | the virulence of salmonella enterica critically depends on the functions of two type iii secretion systems (t3ss), with the salmonella pathogenicity island 1 (spi1)-encoded t3ss required for host cell invasion and the spi2-t3ss enabling salmonella to proliferate within host cells. a further t3ss is required for the assembly of the flagella. most serovars of salmonella also possess a lipopolysaccharide with a complex o-antigen (oag) structure. the number of oag units attached to the core polysacc ... | 2009 | 19797066 |
| bacterial growth rate and host factors as determinants of intracellular bacterial distributions in systemic salmonella enterica infections. | bacteria of the species salmonella enterica cause a range of life-threatening diseases in humans and animals worldwide. the within-host quantitative, spatial, and temporal dynamics of s. enterica interactions are key to understanding how immunity acts on these infections and how bacteria evade immune surveillance. in this study, we test hypotheses generated from mathematical models of in vivo dynamics of salmonella infections with experimental observation of bacteria at the single-cell level in ... | 2009 | 19797065 |
| diagnosis of endotoxemia with gram-negative bacteremia is bacterial species dependent: a meta-analysis of clinical studies. | endotoxemia is undetectable for up to 60% of cases of bacteremia caused by gram-negative (gn) species, a discordance attributed to the limitations of the limulus assay for endotoxemia. the lipid a structure of the endotoxin molecule is critical for the sensing of gn bacteria by the host immune system although not so for sensing by the limulus assay. the lipid a structure of commensal enterobacteriaceae is hexa-acyl, whereas non-enterobacteriaceae have a broader range of structures. by using a pr ... | 2009 | 19794055 |
| salmonella enterica serovar typhi with ctx-m beta-lactamase, germany. | 2009 | 19788837 | |
| the plague of athens: epidemiology and paleopathology. | in 430 bc, a plague struck the city of athens, which was then under siege by sparta during the peloponnesian war (431-404 bc). in the next 3 years, most of the population was infected, and perhaps as many as 75,000 to 100,000 people, 25% of the city's population, died. the athenian general and historian thucydides left an eye-witness account of this plague and a detailed description to allow future generations to identify the disease should it break out again. because of the importance of thucyd ... | 2009 | 19787658 |
| characterization of the first extended-spectrum beta-lactamase-producing nontyphoidal salmonella strains isolated in tehran, iran. | the infections caused by salmonella remain a significant public health problem throughout the world. beta-lactams and fluoroquinolones are generally used to treat invasive salmonella infections, but emergence and spread of antibiotic-resistant strains are being increasingly notified in many countries. in particular, detection of extended-spectrum beta-lactamases (esbls) in salmonella spp. is a newly emerging threat worldwide. this study was carried out to characterize beta-lactamase-producing sa ... | 2010 | 19785534 |
| characterization of extended-spectrum cephalosporin-resistant salmonella enterica serovar heidelberg isolated from humans in the united states. | during the past decade, extended-spectrum cephalosporin resistance has increased among human isolates of salmonella enterica serovar heidelberg, the fourth most common serotype in the united states. we therefore characterized 54 heidelberg isolates with decreased susceptibility (minimum inhibitory concentrations >or=2 mg/l) to ceftriaxone or ceftiofur; 49 (90.7%) contained the cmy-type beta-lactamase (bla(cmy)) gene. the 49 bla(cmy)-positive human heidelberg isolates demonstrated a high degree o ... | 2010 | 19785533 |
| synergistic antibacterial and anti-inflammatory activity of temporin a and modified temporin b in vivo. | temporins are antimicrobial peptides secreted by the granular glands of the european red frog (rana temporaria). they are 10-14 amino acid long polypeptides active prevalently against gram positive bacteria. this study shows that a synthetic temporin b analogue (tb-yk), acquires the capacity to act in synergism with temporin a and to exert antimicrobial and anti-inflammatory activity in vivo against gram positive and gram negative bacteria. administration of 3.4 mg/kg of temporin a (ta)+1.6 mg/k ... | 2009 | 19784377 |
| effect of carbohydrate composition in barley and oat cultivars on microbial ecophysiology and proliferation of salmonella enterica in an in vitro model of the porcine gastrointestinal tract. | the influence of the carbohydrate (cho) composition of cereal cultivars on microbial ecophysiology was studied using an in vitro model of the porcine gastrointestinal tract. ten hull-less barley cultivars, six barley cultivars with hulls, six oat cultivars, and six oat groats that differed in beta-glucan, nonstarch polysaccharide (nsp), and starch contents and starch type were hydrolyzed enzymatically and incubated for 72 h with pig feces. fermentation kinetics were modeled, and microbial compos ... | 2009 | 19783749 |
| differential involvement of atg16l1 in crohn disease and canonical autophagy: analysis of the organization of the atg16l1 complex in fibroblasts. | a single nucleotide polymorphism in atg16l1, an autophagy-related gene (atg), is a risk factor for crohn disease, a major form of chronic inflammatory bowel disease. however, it is still unknown how the atg16l1 variant contributes to disease development. the atg16l1 protein possesses a c-terminal wd repeat domain whose function is entirely unknown, and the crohn disease-associated mutation (t300a) is within this domain. to elucidate the function of the wd repeat domain, we established an experim ... | 2009 | 19783656 |
| comparative genomics of ethanolamine utilization. | ethanolamine can be used as a source of carbon and nitrogen by phylogenetically diverse bacteria. ethanolamine-ammonia lyase, the enzyme that breaks ethanolamine into acetaldehyde and ammonia, is encoded by the gene tandem eutbc. despite extensive studies of ethanolamine utilization in salmonella enterica serovar typhimurium, much remains to be learned about eutbc structure and catalytic mechanism, about the evolutionary origin of ethanolamine utilization, and about regulatory links between the ... | 2009 | 19783625 |
| luxs-based quorum sensing does not affect the ability of salmonella enterica serovar typhimurium to express the spi-1 type 3 secretion system, induce membrane ruffles, or invade epithelial cells. | bacterial species can communicate by producing and sensing small autoinducer molecules by a process known as quorum sensing. salmonella enterica produces autoinducer 2 (ai-2) via the luxs synthase gene, which is used by some bacterial pathogens to coordinate virulence gene expression with population density. we investigated whether the luxs gene might affect the ability of salmonella enterica serovar typhimurium to invade epithelial cells. no differences were found between the wild-type strain o ... | 2009 | 19783624 |
| promoter strength properties of the complete sigma e regulon of escherichia coli and salmonella enterica. | the sigma(e)-directed envelope stress response maintains outer membrane homeostasis and is an important virulence determinant upon host infection in escherichia coli and related bacteria. sigma(e) is activated by at least two distinct mechanisms: accumulation of outer membrane porin precursors and an increase in the alarmone ppgpp upon transition to stationary phase. expression of the sigma(e) regulon is driven from a suite of approximately 60 sigma(e)-dependent promoters. using green fluorescen ... | 2009 | 19783623 |
| integration of microfiltration and anion-exchange nanoparticles-based magnetic separation with maldi mass spectrometry for bacterial analysis. | matrix-assisted laser desorption ionization mass spectrometry (maldi-ms) is powerful in characterizing and identifying bacterial isolates. however, sufficient quantities of bacterial cells are required for generating maldi mass spectra and a procedure to isolate and enrich target bacteria from sample matrix prior to maldi-ms analysis is often necessary. in this paper, anion-exchange superparamagnetic nanoparticles (nps), i.e., fluidmag-deae and fluidmag-q, were employed to capture aeromonas, sal ... | 2009 | 19782231 |
| effects of yeast probiotic formulation on viability, revival and protection against infection with salmonella enterica ssp. enterica serovar typhimurium in mice. | to compare the effects of five yeast probiotic formulations on viability, revival and washout kinetic in the digestive tract of mice, and the protection against an experimental infection with salmonella enterica serovar typhimurium. | 2009 | 19780950 |
| identification of a new promoter for the response regulator rcsb expression in salmonella enterica serovar typhimurium. | the rcscdb (rcs) phosphorelay system regulates capsule synthesis, flagella production and other cellular activities in several enteric bacteria. this system consists of three proteins: the sensor rcsc, the cognate response regulator rcsb and the histidine-containing phosphotransfer protein rcsd (yojn), which is hypothesized to act as an intermediary in the phosphotransfer from rcsc to rcsb. the rcsc gene is convergently transcribed toward rcsb, which follows rcsd in what appears to be a two-gene ... | 2009 | 19780840 |
| real-time fret pcr assay for salmonella enterica serotype detection in food. | salmonella enterica subsp. enterica serotypes are leading etiological agents of food-borne gastroenteritis. traditional identification is laborious and time intensive. faster molecular methods may allow early identification in contaminated food products. we developed a real-time, fluorescence resonance energy transfer hybridization probe polymerase chain reaction (pcr) assay for s. enterica serotypes on the basis of the exclusive presence of the apee gene in salmonella typhimurium. assay sensiti ... | 2009 | 19780376 |
| selective inhibition of type iii secretion activated signaling by the salmonella effector avra. | salmonella enterica utilizes a type iii secretion system (ttss) encoded in its pathogenicity island 1 to mediate its initial interactions with intestinal epithelial cells, which are characterized by the stimulation of actin cytoskeleton reorganization and a profound reprogramming of gene expression. these responses result from the stimulation of rho-family gtpases and downstream signaling pathways by specific effector proteins delivered by this ttss. we show here that avra, an effector protein o ... | 2009 | 19779561 |
| decreased fluoroquinolone susceptibility in mutants of salmonella serovars other than typhimurium: detection of novel mutations involved in modulated expression of rama and soxs. | mutants of five salmonella enterica serovars were investigated for structural changes in regulatory regions known to be involved in the up-regulation of efflux pumps. | 2009 | 19778917 |
| dogs can harbour more than fleas. | 2009 | 19778761 | |
| growth and survival of antibiotic-resistant salmonella typhimurium dt104 in liquid egg products. | since 11 september 2001, quality and food safety are no longer the concerns of only consumers, industry, regulatory agencies, or other government officials. liquid foods that are prepared or stored in bulk, including liquid egg products, are considered to be at potential risk for sabotage. because of their versatility, low price, and functional properties, many of these products are being marketed. four of the most common products of this type are whole egg, egg albumen, 10% sugared yolk, and 10 ... | 2009 | 19777905 |
| molecular characterization of biofilm formation and attachment of salmonella enterica serovar typhimurium dt104 on food contact surfaces. | the molecular mechanism of biofilm formation by salmonella typhimuriun dt104 was characterized for a better understanding of its attachment and colonization in food processing environments. a library of random mutagenized clones was screened for phenotypic analyses of their ability to form biofilm, pellicle, curli, and cellulose. the genes identified were involved in lipopolysaccharide synthesis, assembly of flagella, regulation of rrna biosynthesis, and outer membrane transportation and signali ... | 2009 | 19777884 |
| planktonic and biofilm communities from 7-day-old chicken cecal microflora cultures: characterization and resistance to salmonella colonization. | information implicating bacterial biofilms as contributory factors in the development of environmental bacterial resistance has been increasing. there is a lack of information regarding the role of biofilms within the microbial ecology of the gastrointestinal tract of food animals. this work used a continuous-flow chemostat model derived from the ceca of 7-day-old chicks to characterize these communities and their ability to neutralize invasion by salmonella enterica serovar typhimurium. we char ... | 2009 | 19777880 |
| mutations in the salmonella enterica serovar choleraesuis camp-receptor protein gene lead to functional defects in the spi-1 type iii secretion system. | salmonella enterica serovar choleraesuis (salmonella choleraesuis) causes a lethal systemic infection (salmonellosis) in swine. live attenuated salmonella choleraesuis vaccines are effective in preventing the disease, and isolates of salmonella choleraesuis with mutations in the camp-receptor protein (crp) gene (salmonella choleraesuis deltacrp) are the most widely used, although the basis of the attenuation remains unclear. the objective of this study was to determine if the attenuated phenotyp ... | 2010 | 19775595 |
| salmonella--the ultimate insider. salmonella virulence factors that modulate intracellular survival. | salmonella enterica serovar typhimurium is a common facultative intracellular pathogen that causes food-borne gastroenteritis in millions of people worldwide. intracellular survival and replication are important virulence determinants and the bacteria can be found in a variety of phagocytic and non-phagocytic cells in vivo. invasion of host cells and intracellular survival are dependent on two type iii secretion systems, t3ss1 and t3ss2, each of which translocates a distinct set of effector prot ... | 2009 | 19775254 |
| functional characterization of ssae, a novel chaperone protein of the type iii secretion system encoded by salmonella pathogenicity island 2. | the type iii secretion system (t3ss) encoded by salmonella pathogenicity island 2 (spi-2) is involved in systemic infection and intracellular replication of salmonella enterica serovar typhimurium. in this study, we investigated the function of ssae, a small cytoplasmic protein encoded within the spi-2 locus, which shows structural similarity to the t3ss class v chaperones. an s. enterica serovar typhimurium ssae mutant failed to secrete spi-2 translocator sseb and spi-2-dependent effector pipb ... | 2009 | 19767440 |
| a protein important for antimicrobial peptide resistance, ydei/omda, is in the periplasm and interacts with ompd/nmpc. | antimicrobial peptides (amps) kill or prevent the growth of microbes. amps are made by virtually all single and multicellular organisms and are encountered by bacteria in diverse environments, including within a host. bacteria use sensor-kinase systems to respond to amps or damage caused by amps. salmonella enterica deploys at least three different sensor-kinase systems to modify gene expression in the presence of amps: phop-phoq, pmra-pmrb, and rcsb-rcsc-rcsd. the ydei gene is regulated by the ... | 2009 | 19767429 |
| thioredoxin 1 participates in the activity of the salmonella enterica serovar typhimurium pathogenicity island 2 type iii secretion system. | the facultative intracellular pathogen salmonella enterica serovar typhimurium relies on its salmonella pathogenicity island 2 (spi2) type iii secretion system (t3ss) for intracellular replication and virulence. we report that the oxidoreductase thioredoxin 1 (trxa) and spi2 are coinduced for expression under in vitro conditions that mimic an intravacuolar environment, that trxa is needed for proper spi2 activity under these conditions, and that trxa is indispensable for spi2 activity in both ph ... | 2009 | 19767428 |
| antioxidant and antibacterial activities of the leaf essential oils of himalayan lauraceae species. | the leaf essential oils from seven himalayan lauraceae species viz. neolitsea pallens, lindera pulcherrima, dodecadenia grandiflora, persea duthiei, persea odoratissima, persea gamblei and phoebe lanceolata exhibited potent antioxidant and antibacterial activities. the in vitro antioxidant activity was assessed by using beta-carotene bleaching assay, reducing power, dpph radical scavenging and inhibition of lipid peroxidation methods. the oils of d. grandiflora and l. pulcherrima showed a potent ... | 2010 | 19766161 |
| effect of iron on cytolysin a expression in salmonella enterica serovar typhi. | previously, a novel protein clya (cytolysin a) has been identified in escherichia coli k-12, salmonella enterica serovars typhi and paratyphi a and shigella. salmonella spp. synthesize substantial amounts of clya upon infection of the human host, although the mechanism by which clya is induced in vivo is unclear. since environmental signals could control the expression of virulence determinants, clya expression in s. typhi ty2 was tested by western blotting in the presence of normal pooled human ... | 2009 | 19763423 |
| nucleolar proteins suppress caenorhabditis elegans innate immunity by inhibiting p53/cep-1. | the tumor suppressor p53 has been implicated in multiple functions that play key roles in health and disease, including ribosome biogenesis, control of aging, and cell cycle regulation. a genetic screen for negative regulators of innate immunity in caenorhabditis elegans led to the identification of a mutation in nol-6, a nucleolar rna-associated protein (nrap), which is involved in ribosome biogenesis and conserved across eukaryotic organisms. mutation or silencing of nol-6 and other nucleolar ... | 2009 | 19763173 |
| emergence of extended-spectrum beta-lactamases in clinical isolates of salmonella enterica in tehran, iran. | the purpose of the current study was to investigate the presence and molecular type(s) of extended-spectrum beta-lactamases (esbls) in salmonella spp. isolates obtained from patients with diarrhea in hospitals of tehran, iran. over a period of 17 months, 129 salmonella spp. were isolated from fecal samples and tested for susceptibility using the kirby-bauer disk diffusion method; then, screening for esbl-producing isolates and determination of their minimum inhibitory concentrations were carried ... | 2009 | 19762986 |
| molecular investigation of salmonella choleraesuis and salmonella hadar strains isolated from humans in turkey. | eleven salmonella choleraesuis and seven salmonella hadar strains isolated from various clinical humand samples were investigated by plasmid profile analysis, enterobacterial repetitive intergenic consensus-polymerase chain reaction (eric-pcr) and pulsed-field gel electrophoresis (pfge) in order to obtain information at a molecular level on the epidemiology of s. choleraesuis and s. hadar, which are significantly present in turkey. plasmid profile analysis showed that 10 (90.9%) of 11 s. cholera ... | 2009 | 19762985 |
| isolated ulcerative skin lesion caused by salmonella weltevreden. | salmonella enterica serovar weltevreden is not a commonly isolated serotype in india. we report isolation of salmonella weltevreden, from an unusual site--an ulcer on the gluteal region of a patient who had undergone coronary artery bypass surgery. to our knowledge, salmonellae have never been reported to cause isolated ulcerative lesions on the skin. this is the first report of an isolated ulcerative lesion on the skin caused by salmonella weltevreden. our findings indicate that there may be mo ... | 2009 | 19762977 |
| dam and its role in pathogenicity of salmonella enterica. | dam methylation is an essential factor involved in the virulence of an increasing number of bacterial pathogens including salmonella enterica. lack of dam methylation causes severe attenuation in animal models. it has been proposed that dysregulation of dam activity is potentially a general strategy for the generation of vaccines against bacterial pathogens. in this review, we focus our attention on the role of methylation by dam protein in regulating bacterial gene expression and virulence in s ... | 2009 | 19762965 |
| high level of resistance to nalidixic acid in salmonella enterica serovar typhi in central india. | fluoroquinolones are the drugs of choice for the treatment of typhoid fever. but the recent increase in minimum inhibitory concentration (mic) values of ciprofloxacin in salmonella typhi may result in delayed response and serious complications. nalidixic acid resistance has been used as an indirect evidence of increased minimum inhibitory concentration for ciprofloxacin in salmonella typhi. | 2009 | 19762961 |
| application of pcr-based serogrouping of selected salmonella serotypes in malaysia. | differentiation of salmonella enterica into its serogroups is important for epidemiological study. the objective of the study was to apply a multiplex pcr targeting serogroups a, b, c1, d, e and vi-positive strains of salmonella enterica commonly found in malaysia. a separate h-typing multiplex pcr which identified flagellar antigen "a", "b" or "d" was also optimized to confirm clinical serotypes, s. paratyphi a and s. typhi. | 2009 | 19762954 |
| exposure of escherichia coli and salmonella enterica serovar typhimurium to triclosan induces a species-specific response, including drug detoxification. | the use of triclosan within various environments has been linked to the development of multiple drug resistance (mdr) through the increased expression of efflux pumps such as acrab-tolc. in this work, we investigate the effect of triclosan exposure in order to ascertain the response of two species to the presence of this widely used biocide. | 2009 | 19759044 |
| salmonella derby cross-protection study. | an avirulent live (avl), salmonella choleraesuis vaccine (salmo shield live [grand laboratories, inc.]) was administered to pigs at weaning or 3 weeks of age. two weeks after vaccination the vaccinated pigs as well as unvaccinated control pigs were challenged intranasally with a commonly isolated environmental salmonella serotype, s. derby. at 2, 4, and 6 weeks after challenge, pigs were euthanized and cultured for s. derby. although the number of pigs in this study was too small to draw any def ... | 2000 | 19757566 |
| drug resistance patterns of salmonella isolates of equine origin from india. | salmonellosis is a zoonosis, and one of the most serious public health and animal health problems. | 2009 | 19755745 |
| characterisation of a live salmonella vaccine stably expressing the mycobacterium tuberculosis ag85b-esat6 fusion protein. | a recombinant salmonella enterica serovar typhimurium (s. typhimurium) vaccine strain was constructed that stably expressed the mycobacterium tuberculosis fusion antigen ag85b-esat6 from the chromosome. live oral vaccination of mice with the salmonella/ag85b-esat6 strain generated a potent anti-ag85b-esat6 t(h)1 response with high antibody titres with a igg2a-bias and significant ifn-gamma production lasting over a 120-day period. when mice primed with the salmonella/ag85b-esat6 vaccine were muc ... | 2009 | 19755145 |
| 2d proteome analysis initiates new insights on the salmonella typhimurium luxs protein. | quorum sensing is a term describing a bacterial communication system mediated by the production and recognition of small signaling molecules. the luxs enzyme, catalyzing the synthesis of ai-2, is conserved in a wide diversity of bacteria. ai-2 has therefore been suggested as an interspecies quorum sensing signal. to investigate the role of endogenous ai-2 in protein expression of the gram-negative pathogen salmonella enterica serovar typhimurium (s. typhimurium), we performed a 2d-dige proteomic ... | 2009 | 19754952 |
| salmonella osteomyelitis in new-onset diabetes mellitus. | salmonella species are rare bacterial isolates in osteomyelitis. this article describes a case of an otherwise healthy, active duty male military member with an insidious onset of right knee pain during a deployment to kuwait. his work-up revealed an infectious process in the distal femur. operative treatment and intravenous antibiotics resolved the infection. intraoperative cultures revealed the rare isolate salmonella enterica serotype c2 (newport). postoperative medical management revealed ne ... | 2009 | 19750996 |
| prevalence and antibiotic-resistance of salmonella isolated from food in morocco. | salmonellosis remains one of the most frequent food-borne diseases worldwide, especially in developing countries. the emergence of antimicrobial resistance in salmonella isolates from food can potentially compromise the treatment of these infections. this investigation was conducted for the first time in morocco both to detect the occurrence of salmonella in foods as well as to determine the antibiotic resistance profile of the salmonella isolates. | 2009 | 19749447 |