Publications

TitleAbstractYear
Filter
PMID(sorted descending)
Filter
inhibition of the growth in vitro of trichophyton mentagrophytes, trichophyton erinacei and microsporum persicolor by miconazole and chlorhexidine.an agar dilution technique was used to assess the minimum inhibitory concentrations (mics) of miconazole, chlorhexidine and a 1:1 combination of both agents for 9 isolates of trichophyton mentagrophytes, 9 isolates of trichophyton erinacei and 5 isolates of microsporum persicolor. mics of chlorhexidine did not vary significantly between the three dermatophyte species tested, but the mics of miconazole alone and in combination with chlorhexidine for t. erinacei were significantly greater that tho ...200516238813
pharmacokinetics of terbinafine in young children treated for tinea capitis.dermatophytes are the most common cause of human fungal infections. response rates to existing therapy are lower than optimal, but newer agents like terbinafine hold promise for improved management of such infections. this investigation was designed to evaluate the single dose and steady state pharmacokinetics of terbinafine in young children with tinea capitis.200516220086
in-vitro antibacterial, antifungal and cytotoxic activities of some coumarins and their metal complexes.a series of new antibacterial and antifungal coumarin-derived compounds and their transition metal complexes [cobalt (ii), copper (ii), nickel (ii) and zinc (ii)] have been synthesized, characterized and screened for their in vitro antibacterial activity against escherichia coli, klebsiella pneumoniae, proteus mirabilis, pseudomonas aeruginosa, salmonella typhi, shigella dysenteriae, bacillus cereus, corynebacterium diphtheriae, staphylococcus aureus and streptococcus pyogenes bacterial strains ...200516206827
prevalence of dermatophytic fungal infections in children: a recent study in anambra state, nigeria.we conducted a recent survey of dermatological fungal infections amongst children in both urban and rural parts of anambra state in the south-east geographical flank of nigeria during the period january 2003 to december 2003. samples were collected from 1624 children with clinically suggestive lesions and also between the ages of 4 and 16. young children aged 7-11 and 4- 6 years had significantly higher incidences (p < 0.05) than their older colleagues aged 12-16 years among samples proved to be ...200516205973
eastern cottontail (sylvilagus floridanus) as carrier of dermatophyte fungi.eastern cottontail (sylvilagus floridanus, fam. leporidae), introduced into piedmont (italy) in the 1960s, was studied as carrier of dermatophyte fungi. of 216 hair samples collected from animals culled between september 1999 and july 2000 in the province of alessandria (piedmont, italy) during a pest control project, 57 (26.4%) yielded dermatophyte colonies. as two different species of dermatophytes grew from two samples, a total of 59 fungal isolates (26.5%) were obtained. six dermatophyte spe ...200516170613
chemical composition and antidermatophytic properties of volatile fractions of hexanic extract from leaves of cupressus lusitanica mill. from cameroon.the chemical composition of five column fractions of hexanic leaf extract of cupressus lusitanica were analysed by gas chromatography and gas chromatography-mass spectrometry and then tested for their antidermatophytic activities using the agar dilution method. the first fraction (f(1)) has only hydrocabon monoterpenes with alpha-pinene (80.0%) as major component. the main constituents of the second fraction (f(2)) were epi-bicyclosesquiphellandrene (35.3%), epi-zonarene (10.3%), 1s, cis-calamen ...200616169171
survey of dermatophytes on clinically normal cats in the southeast of england.to report the incidence of dermatophytes on the hair coat of asymptomatic cats in the southeast of england. asymptomatic cats are often blamed for transmission of dermatophytes between animals and humans. this study may help to clarify whether cats are responsible for the increase in fungal infections among the human population.200516167594
phenotypical and molecular characterization of microsporum canis strains in north-east brazil.this study investigated the possible correlation between the phenotypical and genotypical characteristics of microsporum canis isolated from cats and dogs in north-east brazil.200516162228
lung cancer in asian women-the environment and genes.the mortality rate of lung cancer in asian women has increased significantly in the past few decades. environmental factors include tobacco smoke (active and environmental), other indoor pollutions (cooking oil vapours, coal burning, fungus spores), diet, and infections. active tobacco smoking is not the major factor. the relative risk of lung cancer among non-smoking women ever exposed to environmental smoke from their husbands was 1.20 from a meta-analysis. cooking oil vapours associated with ...200516135162
[enzyme activities of dermatophytes isolated from different clinical samples by apizym method].dermatophytes' enzymes may have a role in chronic superficial infections. in this study it was planned to investigate the possible relationship between the enzymatic activities of the dermatophytes and acute or chronic course of the infections. dermatophytes were isolated from 58 (72%) out of 81 patients with superficial infections. the infections were divided into two groups as acute (< or = 6 weeks) or chronic (> 6 weeks). isolated fungi were identified by the classical methods and apizym meth ...200516128029
heat stable antimicrobial activity of allium ascalonicum against bacteria and fungi.to study antimicrobial activity of shallot in comparison with that of garlic and onion against 23 strains of fungi and bacteria, water extracts of garlic, shallot and onion bulbs were prepared. each extract was studied in different forms for their antimicrobial activity viz., fresh extract, dry extract and autoclaved extract. minimal inhibitory concentration and minimal lethal concentrations of these extracts were determined against all organisms by broth dilution susceptibility test. fresh extr ...200516121720
antifungal susceptibility and genotypical pattern of microsporum canis strains.dermatophytes are a group of fungi that are capable of invading keratinized tissues of humans and other animals. antifungal susceptibility analysis and genetic studies by random amplification of polymorphic dna (rapd), have been used to detect polymorphism as well as determining the possible resistance of dermatophytes to antifungals. the aim of this study was to evaluate the possible correlation between the antifungal susceptibility and genotypical pattern of microsporum canis strains isolated ...200516121230
dermatophytes can trigger cooperative (camp-like) haemolytic reactions.dermatophytes usually grow on skin that is also colonized by bacteria. therefore, a possible interaction between dermatophytes and bacteria is of potential relevance for the pathogenesis of skin infections. cell membranes contribute substantially to epidermal barrier function. erythrocyte haemolysis is a model commonly used to study membrane-damaging effects of microbial factors. cooperative (camp-like) haemolytic reactions are known from distinct bacteria, but not from dermatophytes and bacteri ...200516120147
metalloprotease gene of arthroderma gypseum.the full-length cdna sequence for metalloprotease (mep) of arthroderma gypseum (one of the teleomorphs of the microsporum gypseum complex) was determined by the 5'-rapid amplification of cdna ends (race) and 3'-race methods using cdna as a template. the full-length cdna sequence of the mep (2,670 bp) gene was proved to encode 677 amino acids. the amino acid sequence of the a. gypseum mep gene shared about 89 and 66% sequence similarity with the conserved region of the microsporum canis mep gene ...200516116253
eighty-four consecutive cases of tinea faciei in siena, a retrospective study (1989-2003).consecutive cases of tinea faciei diagnosed in siena between 1989 and 2003 were studied retrospectively for differences in clinical form, demographic data and species of dermatophyte isolated. the series consisted of 84 cases (59 females, 25 males) with a mean age of 27 years. mean age of females (32.4 years) was significantly greater than that of males (14.2 years). the dermatophytes most frequently isolated were microsporum canis (38 cases) and trichophyton rubrum (31 cases). clinical form was ...200516115106
antifungal activities of extracts from thai medicinal plants against opportunistic fungal pathogens associated with aids patients.summary in this study, 36 extracts derived from 10 plant species were selected to screen for their antifungal activity against clinical isolates of candida albicans, cryptococcus neoformans and microsporum gypseum. selection was based on their use by traditional thai healers or their reported antimicrobial activities in an attempt to find bioactive medicines for use in the treatment of opportunistic fungal infections in aids patients. the disc diffusion and hyphal extension-inhibition assays wer ...200516115104
seasonal 4-year investigation into the role of the alpine marmot (marmota marmota) as a carrier of zoophilic dermatophytes.two hundred and six samples of alpine marmot (mamota marmota) hair (148 from adults and 58 from young subjects), 102 soil samples from the entrances to the burrows of the above individuals and 20 control specimens (obtained from adjoining areas away from the burrow systems where the rodents are not usually present) were examined from may 1994 to september 1997. seventy-five isolates belonging to six species of dermatophytes were found in 69 of the 206 hair samples examined (33.5%). two species w ...200516110784
dermatophytes growth curve and in vitro susceptibility test: a broth micro-titration method.the introduction of systemic antifungal drugs which act upon different targets is the main issue of the in vivo antifungal resistance control. different factors, such as growth curve phase, quality of the specimen, quantity of the inoculum, temperature, ph, culture medium composition, incubation duration and solvent, are believed important factors affecting minimum inhibitory concentration (mic) value to most of the antifungal agents. we assayed an in vitro susceptibility test with 40 isolates o ...200516110777
[an unusual cause of pulmonary cysts].multiple pathologies may be associated with cystic appearances in the lungs. lymphangioleiomyomatosis, langerhans cell histiocytosis and lymphocytic interstitial pneumonia are the principal causes of thin walled pulmonary cysts.200516092168
antifungal susceptibilities of dermatophytic agents isolated from clinical specimens.the aim of this study was to investigate the susceptibility to four antifungal agents: ketoconazole, terbinafine, itraconazole and fluconazole, of the different species of dermatophyte strains isolated from clinical specimens. a total of 128 specimens were collected from toe nail, foot, inguinal region, trunk, hands and head. the dermatophytes tested included trichophyton rubrum 108 (84.4%), trichophyton mentagrophytes 11 (8.6%), epidermophyton floccosum 5 (3.9%), microsporum canis 2 (1.5%) and ...200516048753
evaluation of antimicrobial activities of several mannich bases and their derivatives.the aim of this study was to evaluate the antimicrobial activities of several mannich bases and their derivatives against pathogenic bacteria and fungi. 3-dimethylamino-1-phenyl-1-propanone hydrochloride (ig1) as mono-mannich base, bis(beta-aroylethyl)methylamine hydrochlorides (b1, b5) as bis-mannich bases, 3-aroyl-4-aryl-1-methyl-4-piperidinol hydrochlorides (c1, c5) as piperidinol derivatives, which are structural isomers of bis-mannich bases, n,n'-bis(3-dimethylamino-1-phenylpropylidene)hydr ...200515981301
inter-single-sequence-repeat-pcr typing as a new tool for identification of microsporum canis strains.microsporum canis is a ubiquitous dermatophyte that commonly causes human infections. since contact with infected animals is the usual way of infection, tracing its source is an essential preventive measure.200515978415
in-vitro antibacterial, antifungal and cytotoxic properties of sulfonamide--derived schiff's bases and their metal complexes.a series of new antibacterial and antifungal schiff's bases derived from sulfonamides, as well as their transition metal complexes incorporating cobalt (ii), copper (ii), nickel (ii) and zinc (ii) were synthesized, characterized and screened for their in-vitro antibacterial activity against six gram-negative (escherichia coli, klebsiella pneumoniae, proteus mirabilis, pseudomonas aeruginosa, salmonella typhi and shigella dysentriae) and four gram-positive (bacillus cereus, corynebacterium diphth ...200515968823
[evaluation the antimycotic activity of itraconazole in human stratum corneum with vitro fungi cultivation].to establish a new model to evaluate the antifungal activity of antimycotics.200515949332
[incidence, immunity and treatment of feline dermatophytosis].feline dermatophytosis is a superficial skin infection characterized by the invasion of cornified tissues such as hair and nails. this infection is nearly always caused by microsporum canis. infected animals release infective spores in the environment which will then contaminate other animals or humans. infected animals usually develop immunity so the infection will spontaneously disappear after a few weeks to months. long haired and immunocom-promised cats do not have the same ability to acquir ...200515929601
fluconazole upregulates sconc expression and inhibits sulphur metabolism in microsporum canis.azole derivatives such as fluconazole are the mainstay of therapeutic agents for the treatment of fungal infections. their mode of action involving alteration in the conversion of lanosterol to ergosterol is well established. here we report the effect of fluconazole on the sulphur metabolism negative regulator gene (sconc) in microsporum canis. characterization of the m. canis sconc gene revealed that its orf is comprised of 495bp interrupted by four introns of 47-70bp. exposure of m. canis in s ...200515922636
antidermatophyte activity of ether extract of nigella sativa and its active principle, thymoquinone.the antifungal activity of ether extract of nigella sativa seed and its active principle thymoquinone was tested against eight species of dermatophytes: four species of trichophyton rubrum and one each of trichophyton interdigitale, trichophyton mentagrophytes, epidermophyton floccosum and microsporum canis. agar diffusion method with serial dilutions of ether extract of nigella sativa, thymoquinone and griseofulvin was employed. the incubation was carried out at 30 degrees c for 14 days. the di ...200515908151
therapeutic options for the treatment of tinea capitis: griseofulvin versus fluconazole.tinea capitis is a relatively common fungal infection of childhood. griseofulvin has been the mainstay of treatment for many years. however, newer oral antifungal agents are being used more frequently.200515897167
organometallic-based antibacterial and antifungal compounds: transition metal complexes of 1,1'-diacetylferrocene-derived thiocarbohydrazone, carbohydrazone, thiosemicarbazone and semicarbazone.organometallic-based, 1,1'-diacetylferrocene-derived antibacterial and antifungal thiocarbohydrazone, carbohydrazone, thiosemicarbazone and semicarbazone have been prepared by condensing equimolar amount of 1,1'-diacetylferrocene with thiocarbohydrazide, carbohydrazide thiosemicarbazide and semicarbazide, respectively. these were used as ligands for the preparation of their cobalt (ii), copper (ii), nickel (ii) and zinc (ii) metal complexes. all the synthesized ligands and their complexes were c ...200515895689
antifungal activities of six south african terminalia species (combretaceae).a serial microplate dilution method developed for bacteria was modified slightly and gave good results with several fungi. the antifungal activity of acetone, hexane, dichloromethane and methanol leaf extracts of six terminalia species (terminalia prunioides, terminalia brachystemma, terminalia sericea, terminalia gazensis, terminalia mollis and terminalia sambesiaca) were tested against five fungal animal pathogens (candida albicans, cryptococcus neoformans, aspergillus fumigatus, microsporum c ...200515894142
etiologic agents of dermatophyte infection in lebanon.dermatophytes are common and cause important human fungal infections in many parts of the world, including lebanon. the prevalence of these fungi, however, tends to vary with time and geographic location. in our region, studies on the prevalence of dermatophytoses and the distribution of the various dermatophyte species involved are rare. in lebanon, only one study was published on this subject over the last forty years.200415884683
in vitro susceptibility testing of microsporum gypseum isolated from healthy cattle and soil samples against itraconazole, terbinafine, fluconazole and topical veterinarian drugs.the present study evaluated in vitro susceptibility testing of dermatophytes isolates from healthy cattle and soil samples against three antifungal agents and three topical veterinarian drugs. itraconazole and terbinafine showed a higher in vitro fungicidal activity than fluconazole. the veterinarian drugs lepecid and iodine 5% were more active in vitro than the unguento spray. all drugs showed fungicidal activity against microsporum gypseum, and they may be considered as efficient agents for th ...200515883722
production of heptaene antifungal antibiotic by streptomyces purpeofuscus cm 1261.a strain of streptomyces purpeofuscus cm 1261 isolated from a sample of compost collected locally was found to possess strong antagonistic activity against 4 human pathogenic fungi i.e., candida albicans, aspergillus niger, microsporum gypseum and trichophyton sp. the active antifungal compound produced by it was found to be a heptaene group of polyene antifungal antibiotic.200515875718
repetitive-sequence-pcr-based dna fingerprinting using the diversilab system for identification of commonly encountered dermatophytes.the performance of repetitive-sequence-based pcr (rep-pcr) using the diversilab system for identification of dermatophytes commonly isolated in a clinical laboratory was assessed by comparing results to those of conventional tests (colony morphology, microscopic examination of slide cultures, and, for suspected trichophyton species, use of additional media). sixty-one cultures were tested in phase 1, the feasibility portion of the study; 64 additional cultures were tested in phase 2, the validat ...200515872233
once-weekly fluconazole in children with tinea capitis due to microsporum canis. 200515868642
mycoses in thailand: current concerns.scytalidium dimidiatum is the leading cause of fungal foot diseases in thailand, in contrast to similar studies in which dermatophytes have been identified as the predominant pathogens. by contrast, the prevalence of candida albicans in our study was only 2.6 approximately 3.0%. scytalidium fungal foot infection is clinically indistinguishable from that caused by dermatophytes and should be included as a possible cause of treatment failure in tinea pedis and onychomycosis. without proper culture ...200515864252
inhibitory effect of the plant boerhavia diffusa l. against the dermatophytic fungus microsporum fulvum.antifungal activity (reduction in colony diameter) of various extracts (pt. ether, chloroform, ethyl acetate, ethyl alcohol and aqueous) of aerial and root parts of boerhavia diffusa (nictaginaceae) was screened against dermatophytic fungi microsporum fulvum. statistically significant increase has been recorded in the % inhibition of the target fungal species with increasing test concentrations (1000-5000 ppm) of chloroform, ethyl acetate and ethyl alcohol extracts of the root. the maximum % inh ...200415847339
development of an enzyme-linked immunosorbant assay (elisa) for the serodiagnosis of canine dermatophytosis caused by microsporum canis.abstract in dogs, dermatophytosis should be considered in any case of alopecic, papular or pustular lesion. the aim of this study was to develop an enzyme-linked immunosorbant assay (elisa) as an aid in the diagnosis of canine dermatophytosis. the antigen used was a whole fungal extract obtained from an isolate of microsporum canis cultured on a liquid medium from the parasitized hair of a cat with patches of alopecia. to assess the elisa performances, sera from 18 dogs with dermatophytosis caus ...200515842540
dermatophyte infections in the ljubljana region, slovenia, 1995-2002.we studied dermatophyte infections in patients, examined in the mycological laboratory of the department of dermatology, university medical centre ljubljana during the period 1995-2002. a total of 42,494 samples were collected from 33,974 patients suspected to have dermatomycosis. dermatophytes were identified in 8286 (71.2%) positive cultures. microsporum canis was the most frequent dermatophyte isolated (46.8%), followed by trichophyton rubrum (36.7%), t. mentagrophytes var. interdigitale (7.9 ...200515842334
antifungal activity of ocimum gratissimum towards dermatophytes.the development of more effective and less toxic antifungal agents is required for the treatment of dermatophytosis. plants and their preparations have been used as medicines against infectious diseases. extracts of ocimum gratissimum leaves were investigated for in vitro antifungal activity, using agar dilution technique against dermatophytes. the extracts (hexane, chloroform fractions, the essential oil and eugenol) produced antifungal activities against microsporum canis, m. gypseum, trichoph ...200515842332
scutular tinea of the scrotum: report of two cases.infections caused by dermathophytes in the scrotal skin are uncommon especially due to microsporum gypseum, which may form scutular or favus-like lesions. we report two patients with this type of tinea: one immune suppressed by hiv infection and another immunocompetent without comorbidity. in the literature we found only two reports in immunocompetent patients and some in immune suppressed with similar symptoms.200515842330
in vitro activities of posaconazole, ravuconazole, terbinafine, itraconazole and fluconazole against dermatophyte, yeast and non-dermatophyte species.the in vitro activities of two new triazole antifungal agents with broad-spectrum antifungal activity, posaconazole and ravuconazole, were compared with those of three well-established antifungal agents, terbinafine, itraconazole and fluconazole, against 184 clinical isolates. these included 129 dermatophyte isolates (twelve species), 25 yeast isolates (five species) and 28 non-dermatophyte isolates (nine species). in vitro testing was conducted using microdilution plates with rpmi 1640 and nati ...200515832561
tinea capitis: a treatment update.currently, many experts consider griseofulvin to be the drug of choice for tinea capitis. it is fda approved for this indication, highly efficacious, and has an excellent long-term safety record. nonetheless, there is now ample evidence documenting the efficacy and safety of other antifungal agents. terbinafine, itraconazole, and fluconazole have been used off-label in the united states and united kingdom for tinea capitis. several studies have shown that short-term terbinafine, itraconazole, or ...200515792111
[animal dermatophytosis. recent advances].the proportion of positive samples in relation to the number of samples examined from cases of dog and cat dermatophytosis varies considerably from one investigation to another. in dogs, it ranges between 4% and 10% and few studies show higher prevalences. on the other hand, the percentages of positive cultures cited in the reviewed literature from dogs with or without suspected dermatophytosis are quite similar. in dogs with suspected lesions of dermatophytosis, with few exceptions, microsporum ...200015762784
keratinophilic fungi isolated from hospital dust and soils of public places at gulbarga, india.keratinophilic fungi were isolated from corridor dust of 11 hospitals and soils of 21 public places using a hair baiting technique. a total of 41 species belonging to 24 genera were recovered. among the dermatophytes and related species, microsporum gypseum was predominant, followed by chrysosporium keratinophilum, trichophyton mentagrophytes, m. nanum and ch. tropicum. other species were represented by 32 species belonging to 21 genera. most of the species isolated are known to be agents of hum ...200515750728
new triorganotin(iv) derivatives of dipeptides as anti-inflammatory-antimicrobial agents.new triorganotin(iv) derivatives of dipeptides with general formulae r(3)sn(hl), where r = me and/or n-bu and/or ph and hl is the monoanion of glycylglycine (h(2)l-1), glycylvaline (h(2)l-2), glycylleucine (h(2)l-3), glycyltryptophane (h(2)l-4) and glycyltyrosine (h(2)l-5) have been synthesized and characterized on the basis of infrared, multinuclear nmr and (119)sn mossbauer spectroscopic studies. all the newly synthesized compounds were examined for their in vivo anti-inflammatory activity (us ...200515725498
comparison of disk diffusion method and broth microdilution method for antifungal susceptibility testing of dermatophytes.the use of the agar diffusion neo-sensitabs method to determine antifungal susceptibility of 59 isolates of dermatophytes, namely epidermophyton floccosum, microsporum canis, m. gypseum, trichophyton mentagrophytes, t. rubrum and t. tonsurans to clotrimazole (clz), itraconazole (itz) and terbinafine (tbf) is described. results obtained are compared to the minimum inhibitory concentrations (mic) determined by an adaptation of the nccls-m38-a procedure. using the diffusion method, all strains show ...200515712608
[dermatophytoses due to microsporum gypseum: report of eight cases and literature review].microsporum gypseum is a geophilic fungus infrequent agent of human dermatophytoses and world-wide in distribution. in cadiz, spain, between 1997 and 2003, a study of 133 positive cases showed that the fifth more isolated dermatophyte was m. gypseum (6.0%), followed by trichophyton mentagrophytes (24,8%), microsporun canis (24,6%), trichophyton rubrum (21,8%) y trichophyton violaceum (6,8%). during 2003 the infection due to this fungus has been repeatedly observed in our area (17.5%). we report ...200415709790
in vitro antifungal activity of dragon's blood from croton urucurana against dermatophytes.based on ethnobotanical approach, the dragon's blood collected from croton urucurana baill. bark (euphorbiaceae) was tested for antifungal activity against five dermatophytes by paper disk diffusion method. the minimal inhibitory concentration (mic) showing no visible fungal growth was also determined, using tube dilution technique. the test dermatophytes were tricophyton tonsurans, trichophyton mentagrophytes, trichophyton rubrum, microsporum canis and epidermophyton floccossum. the dragon's bl ...200515707783
[investigation of the inter-observer agreement rates for morphometric evaluation of the growth of microsporum canis colonies].morphometry is a newly applied method for investigation of the in-vitro growth dynamics of dermatophyte colonies. this study was undertaken to evaluate the correlation and agreement rates between the morphometric data obtained by different observers. for this purpose, five different microsporum canis growth data were evaluated by six observers. the results of the study suggested that the agreement rates among the data obtained by different observers were low (r1 = -5.3509), while the results obt ...200415700671
[dermatophyte species isolated from patients prediagnosed as onychomycosis and the value of fungal culture].in this study, the clinical specimens taken from 390 patients who were prediagnosed as onychomycosis have been investigated by direct microscopy and culture methods, in the mycology unit of central laboratory of kocaeli university medical faculty. twenty-one (41.2%) of the 51 microscopically positive samples revealed positive cultures for dermatophytes, whereas 32 (9.4%) samples were culture positive among the 399 samples which were microscopically negative. the most frequently isolated dermatop ...200415700670
evaluation of microsporum canis in different methods of storage.the main objective of this investigation was to evaluate different methods of storage for microsporum canis based on materials and equipment that are readily available in developing countries. we tested 32 strains of m. canis at - 20 degrees c in potato dextrose agar (pda) in its plain condition, or amended with 10% dimethyl sulfoxide or with 10% glycerol. in addition, we tested 25 degrees c storage of isolates in plain saline (0.9% nacl) and in saline covered with a mineral-oil layer. after 9 m ...200415682637
dermatophytosis on the eyelid caused by microsporum gypseum.we report a case of tinea on the eyelid in a woman with psoriasis. due to the history of psoriasis and clinical aspect of the lesion the diagnosis of psoriasis was suggested in the first place; however, laboratory examination revealed microsporum gypseum. the patient was treated with oral itraconazole resulting in clinical and mycological cure. we emphasize the uncommon location of tinea caused by m. gypseum and the importance of searching for fungal infection on scaly lesions.200515679671
characteristics of dermatophytoses among children in an area south of tehran, iran.the aim of this study was to determine the prevalence and etiological agents of dermatophytoses, and also their distribution according to age, gender, and body site among children in an area south of tehran. a total of 382 children aged </=16 years suspected to have dermatophytic lesions were examined over a period of 3 years (1999-2001). the incidence rate of dermatophytoses was 6.6 per 100 000 person-years. trichophyton violaceum was the most frequent isolate (28.3%) followed by microsporum ca ...200515679663
epidemiology of dermatomycoses in children living in northern greece 1996-2000.in the 5-years period, 1996-2000, 1045 children under 13 years old were examined for suspected dermatomycosis. in 611 cases fungi were isolated. male children were mainly affected on the scalp and body area. girls were more affected in the location of the arms and legs. there was a greater proportion of cases in the age range 2-12 years. the most prominent fungus was microsporum canis (515 cases) followed by trichophyton rubrum (34) and candida albicans (20). tinea capitis (280 cases) mainly cau ...200515679659
tinea capitis in diyarbakir, turkey.the incidence and types of tinea capitis in 234 children aged 1-12 referred to our laboratory with a preliminary diagnosis of tinea capitis infection in the past 5 years were investigated. tinea capitis was determined in 149 (63.7%) of these patients, of which agents grew in culture in 124 (83.2%). the most frequently isolated agents, in order of frequency, are as follows: trichophyton violaceum (43.6%), microsporum canis (37.9%), t. mentagrophytes (8.1%) and t. verrucosum (4.8%).200515679658
use of magnetic beads to extract fungal dna.authors compare two methods of extracting dna from different fungi: the classic method with phenol/chloroform (p/c) and that with magnetic beads. both were tested on candida albicans and cryptococcus neoformans var. neoformans, belonging to the yeast group and microsporum canis, m. gypseum, trichophyton rubrum, t. interdigitale, t. ajelloi, epidermophyton floccosum, belonging to the dermatophytes group. extraction products underwent polymerase chain reaction (pcr) fingerprinting with the appropr ...200515679657
[inflammatory lesion with a black scab on the face of a 16-year old girl]. 200515657728
isatin-derived antibacterial and antifungal compounds and their transition metal complexes.a series of isatins incorporating thiazole, thiadiazole, benzothiazole and p-toluene sulfonyl hydrazide moieties, along with their cobalt(ii), copper(ii), nickel(ii) and zinc(ii) metal complexes have been synthesized and characterized by elemental analyses, molar conductances, magnetic moments, ir, nmr and electronic spectral data. these compounds have been screened for antibacterial activity against escherichia coli, bacillus subtillis, shigella flexneri, staphylococcus aureus, pseudomonas aeru ...200415648656
keratinophilic fungi of poultry farm and feather dumping soil in tamil nadu, india.soils of 10 poultry farms from namakkal and 12 feather dumping sites from chennai were studied for the presence of keratinophilic fungi. a total of 34 species belonging to 19 genera and one non-sporulating fungus were recovered. sixteen species of fungi and one non-sporulating fungi were common to both sites, eight species were specific to namakkal and nine species were specific to chennai. dermatophytes and closely related fungi were represented by six species belonging to five genera. fungal s ...200415645172
evaluation of inhibitory effect of the plant phyllanthus amarus against dermatophytic fungi microsporum gypseum.the antifungal activity of various solvent extracts (such as ether, chloroform, ethyl acetate and ethyl alcohol) of the plant phyllanthus amarus against dermatophytic fungi microsporum gypseum was observed.200415602834
the epidemiology of canine and feline dermatophytoses in southern italy.a total of 424 animals (268 dogs and 156 cats) with skin lesions (alopecia and peripheral scaling) were examined from january 1999 to december 2002. of the 424 samples examined, 99 (23.3%) yielded a positive culture and, in particular, 20.5% of the dog samples and 28.2% of the cat samples. microsporum canis was the most common dermatophyte isolated from dogs and cats (77.7%), followed by geophilic dermatophyte species (m. gypseum, trichophyton terrestre). young dogs and cats, especially those yo ...200415601458
in vitro evaluation of griseofulvin against clinical isolates of dermatophytes from isfahan.fifty dermatophyte isolates, recently obtained from clinical materials, belonging to trichophyton mentagrophytes, t. verrucosum, microsporum canis and epidermophyton floccosum were examined for their susceptibility to griseofulvin. the minimum inhibitory concentration (mic) values were obtained using the modified microdilution method. all 100% tested isolates had mic geometric mean at a concentration between 0.43 and 0.95 microg ml(-1) the mic(90)s and mic(50)s were 8 microg ml(-1) and <0.25-1 m ...200415601457
efficacy of pre-treatment with lufenuron for the prevention of microsporum canis infection in a feline direct topical challenge model.oral lufenuron is reportedly an effective treatment for some cats with dermatophytosis. the purpose of this study was to determine if lufenuron, when used as a pre-treatment prior to challenge exposure, would be protective against the development of infection after the direct topical application of fungal macrocondia (microsporum canis spores). three groups (n = 6/group) of juvenile cats were treated with either monthly oral lufenuron (30 or 133 mg/kg) or placebo. after 2 months of treatment, ki ...200415585010
antimicrobial and free radical scavenging activity of gentianella nitida.the antimicrobial and free radical scavenging activity of the ethanol extract and fractions of gentianella nitida have been assessed. the most susceptible microorganisms were candida albicans, trichophyton mentagrophytes and microsporum gypseum. the antifungal activity was concentrated in the 90% methanol and nonsoluble fractions, while the radical scavenging activity was stronger in the ethyl acetate and nonsoluble fractions.200415567257
clinical and epidemiological study in an aids patient with microsporum gypseum infection.a 37 years old homosexual male with aids was diagnosed as having tinea cruris and tinea corporis. the patient was a garden designer and therefore he used to handle soil very often. microsporum gypseum was identified on cultures from skin-scrapings and biopsy material taken from different cutaneous lesion. the same species was isolated from samples of soil the patient used to work with. the clinical history of the patient and its epidemiological aspects were deeply studied by the authors. we stre ...199715538824
myths and misconceptions: not all that glitters under the watch is gold (nickel) dermatitis. 200415538087
diversity of keratinophilic mycoflora in the soil of agra (india).diversity of keratinophilic mycoflora in the soil of agra was under observation for 1 year (july 2001-june 2002) and isolation of keratinophilic fungi was followed by the hair-baiting method. the frequency of occurrence of keratinophilic fungi in 284 soil samples collected from various hospitals, cattle yards, poultry farms, crop fields and playgrounds was determined, 204 samples (72%) having been found to be positive. a total of 33 species classified into 11 genera (acremonium, aspergillus, chr ...200415530009
griseofulvin versus terbinafine in the treatment of tinea capitis: a meta-analysis of randomized, clinical trials.tinea capitis, a common pediatric infection in the united states, is caused mainly by trichophyton species and affects many urban children. although the current treatment of choice is oral griseofulvin, terbinafine has been shown to be variably effective in several comparative, randomized trials. the purpose of this study was to perform a meta-analysis of randomized, clinical trials comparing the efficacies of oral terbinafine and oral griseofulvin for the treatment of childhood tinea capitis.200415520113
bizarre annular lesion emerging as tinea incognito.tinea incognito has first been described in 1968. the term describes a tinea infection whose clinical morphology has been modified by the application of topical corticosteroids. the clinical manifestation can masquerade a number of other dermatoses and leads to misdiagnosis of annular eruptions. we describe a patient who showed a bizarre appearance of annular, inflammatory skin lesions at the umbilical region. mycological culture yielded microsporum canis.200415504132
tinea capitis caused by microsporum canis treated with terbinafine.tinea capitis is a disease found throughout the world. it frequently affects children and only rarely adults, usually post-menopausal women. numerous dermatophytes of the genus microsporum and tricophyton can cause tinea capitis and griseofulvin is still today the treatment of choice. to study the effectiveness and tolerability of terbinafine treatment in tinea capitis caused by microsporum canis we treated 26 patients - 22 children and four women - for a period of 12 weeks. dosage adopted was 6 ...200415504128
stereoselective synthesis and antifungal activity of (z)-trans-3-azolyl-2-methylchromanone oxime ethers.a series of (z)-trans-3-azolyl-2-methylchromanone oxime ethers were stereoselectively synthesized and tested for in vitro antifungal activity. many of these derivatives exhibit high activity against candida albicans, saccharomyces cerevisiae, aspergillus niger, and microsporum gypseum.200415498664
tinea capitis in infants in their first year of life.tinea capitis is the most common type of dermatophytosis in children, but is uncommon in the first year of life.200415491432
[tinea capitis by microsporum audouinii].we report the case of a four year-old girl from equatorial guinea who had been living in spain for the last month. she presented several alopecic patches on the scalp. the direct study of the hair with 40% koh showed an ectothrix infection and the mycological study revealed the etiologic agent was microsporum audouinii. we present this case because of its rarity in our country and we point out the increasing interest of the imported tineas due to immigration from african countries.200115487914
[epidemiology of tinea capitis in abidjan, cote d'ivoire].tinea capitis is a dermatosis of the scalp due to dermatophytes that can cause hair loss. it remains a significant endemic problem mainly in school children in tropical regions. the purpose of this case-control study carried out in the dermatology center of treichville hospital was to identify risk factors for tinea capitis in abidjan, cote d'ivoire. a total of 80 cases were recruited on the basis of clinical findings showing one or several plaques showing desquamation or parakeratosis suggestiv ...200415460148
[superficial infections caused by microsporum canis in humans and animals].dermatophytic infections caused by m. canis in humans and animals have a world wide distribution and they are zoonotic. the objective in this work was to know the frequency of m. canis infections in humans and pets. we studied our cases from january 1994 to december 2002. the human samples were obtained from a dermatological department in a general hospital and we registered the next data: age, sex, job, and affected area. the animal samples were obtained from a mycological veterinary laboratory ...200415458362
[canine onychomycosis produced by microsporum gypseum. a case report].one case of severe canine onychomycosis is described. the aetiological agent was identified as microsporum gypseum. the incidence of this fungus in this kind of pathology is discussed, with special attention to the successful treatment with topic enilconazole and systemic griseofulvin.200315456357
[dermatophyte infection and colonization in dogs from south santiago, chile].our main aim was to determine the dermatophyte infection and colonization prevalence in canines from south santiago, chile. we studied 241 dogs, 121 of them presented cutaneous lesions suggestive of dermatophytosis and the other 120 were free from lesions and were considered clinically healthy. dermatophytes were isolated from the lesions of 48.8% of animals with cutaneous diseases and from 5% of healthy dogs. microsporum canis was the principal species isolated with a frequency of 98.3% from de ...200315456352
lung cancer epidemiology and risk factors in asia and africa.in industrialised countries, lung cancer is the most common form of cancer among males and it is growing among females. for both sexes, rates reflect smoking behaviours. the pattern appears to be different in asia, particularly in china, where lung cancer rates in men reflect high smoking rates but high rates among non-smoking women appear to be related to other factors. the incidence of lung cancer is low in most african countries, but it is increasing. in addition to tobacco smoking, a number ...200415455588
origins of onychomycosis.onychomycosis, or tinea unguium, is generically thought of as a fungus infection of the nails characterized by thickening, splitting, roughening, and discoloration. this article discusses the origins of this condition as well as methods of classification and evaluation.200415450895
population structure and evolutionary origins of microsporum canis, m. ferrugineum and m. audouinii.the recurrent evolutionary emergence of asexual lineages within sexual zoo- and anthropophilic dermatophyte species living in animal-frequented soil is likely to be triggered by changes in ecological niche, i.e., shifts of host animal. subsequent adaptation to the new host species is noted. sometimes geographic isolation or intrinsic host factors like human race may also play a role in speciation. in the present study, we elaborate concepts of speciation in dermatophytes using the microsporum ca ...200415450196
antibacterial and antifugal mono- and di-substituted symmetrical and unsymmetrical triazine-derived schiff-bases and their transition metal complexes.a new series of antibacterial and antifungal triazine-derived mono- and di-substituted (symmetrical and unsymmetrical) schiff-bases and their cobalt(ii), copper(ii), nickel(ii) and zinc(ii) metal complexes have been synthesized and characterized by their elemental analyses, molar conductances, magnetic moments and ir and electronic spectral measurements. ir spectra indicated the ligands to act as tridentate towards divalent metal ions via a trazine-n, the azomethine-n and, indole-nh and deproton ...200415449731
[epidemiologic and sociohygenic observations on two epidemics of microsporia in cologne]. 195015439940
[microsporotic focus on the scalp]. 195015435114
[microsporotic focus on lanuginous skin, clinically indifferentiable from trichophytosis]. 195015435113
[data on the symptomatology of superficial microsporiasis of the scalp]. 195015434203
large spores (macroconidia, fuseaux) of microsporum audouini in vivo; report of a case. 195015433436
effect of yeast extract on microsporum audouini and microsporum canis. 195015433400
endemic of infection with microsporum audouinii in a family of eight persons. 195015426315
physiological studies on the genus microsporum. 195015422186
immunity of the adult scalp to infection with microsporum audouinii. 195015422183
[efficacy sex hormones in the treatment of microsporia]. 195015412006
[determatologica; results of different methods of treatment of trichophytosis]. 195015411408
microsporum gypsum as an etiologic agent of tinea in the united states. 195015411223
fuseaux formation of the genus microsporum. 195015404858
what is your diagnosis? dermatophytic pseudomycetoma. 200415352405
a survey on the pathogenic fungi in soil samples of potted plants from sari hospitals, iran.a total of 23 soil samples of potted plants was collected from hospitals in sari, iran. each sample contained approximately 200 g soil, taken from a depth of 0-10 cm of the pots. samples were analysed by two different methods. (1) culture on sabouraud's dextrose agar medium containing chloramphenicol (sc); cultured fungi were identified by macroscopic and microscopic characterization. (2) the hair-baiting technique (hbt) was used to isolate the keratinophilic fungi. after culture on sc medium, 1 ...200415350715
[identification of geophilic and zoophilic dermatophytes in siblings with tinea capitis. a pathogenic factor or contamination?].two siblings of african origin presented with multiple scaling patches and alopecia on the scalp four weeks after returning from a vacation in eritrea. direct koh examination revealed fungal elements; trichophyton mentagrophytes and trichophyton terrestre were identified in the fungal culture. we discuss the putative pathogenic role of both microorganisms in causing disease. although infection with microsporum canis currently accounts for almost fifty percent of all cases of tinea capitis in ger ...200415340708
the novel azole r126638 is a selective inhibitor of ergosterol synthesis in candida albicans, trichophyton spp., and microsporum canis.r126638 is a novel triazole with in vitro activity similar to that of itraconazole against dermatophytes, candida spp., and malassezia spp. in animal models of dermatophyte infections, r126638 showed superior antifungal activity. r126638 inhibits ergosterol synthesis in candida albicans, trichophyton mentagrophytes, trichophyton rubrum, and microsporum canis at nanomolar concentrations, with 50% inhibitory concentrations (ic(50)s) similar to those of itraconazole. the decreased synthesis of ergo ...200415328084
dermatophytosis in children and adolescents in gdansk, poland.during a 3-year period (1999-2001) a total of 94 cases of dermatophytosis were seen in patients from 0 to 18 years of age attending the department of dermatology, venerology and allergology of gdaƄsk medical university. mycoses were diagnosed on the basis of clinical picture and direct microscopy and were confirmed by positive cultures. the most frequent pathogens were microsporum canis (62%) and trichophyton rubrum (12%). the most often forms of dermatophytosis in children were tinea cutis glab ...200415310339
Displaying items 501 - 600 of 3121